Amino acid dipepetide frequency for Eptesicus serotinus papillomavirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.23AlaAla: 4.23 ± 0.915
0.846AlaCys: 0.846 ± 0.628
3.807AlaAsp: 3.807 ± 1.276
5.499AlaGlu: 5.499 ± 1.219
4.23AlaPhe: 4.23 ± 1.161
4.23AlaGly: 4.23 ± 0.63
0.423AlaHis: 0.423 ± 0.314
2.538AlaIle: 2.538 ± 0.625
2.961AlaLys: 2.961 ± 1.826
6.768AlaLeu: 6.768 ± 2.198
0.846AlaMet: 0.846 ± 0.628
2.115AlaAsn: 2.115 ± 1.138
3.384AlaPro: 3.384 ± 0.795
1.269AlaGln: 1.269 ± 0.751
5.499AlaArg: 5.499 ± 2.392
5.076AlaSer: 5.076 ± 2.166
4.653AlaThr: 4.653 ± 1.404
2.961AlaVal: 2.961 ± 0.793
1.269AlaTrp: 1.269 ± 0.799
0.846AlaTyr: 0.846 ± 0.514
0.0AlaXaa: 0.0 ± 0.0
Cys
2.115CysAla: 2.115 ± 1.138
0.423CysCys: 0.423 ± 0.445
0.846CysAsp: 0.846 ± 0.514
0.846CysGlu: 0.846 ± 0.628
0.423CysPhe: 0.423 ± 0.445
0.423CysGly: 0.423 ± 0.445
0.0CysHis: 0.0 ± 0.0
1.692CysIle: 1.692 ± 1.079
0.846CysLys: 0.846 ± 0.576
2.961CysLeu: 2.961 ± 1.915
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.692CysPro: 1.692 ± 0.882
0.0CysGln: 0.0 ± 0.0
0.423CysArg: 0.423 ± 0.314
1.692CysSer: 1.692 ± 0.86
1.269CysThr: 1.269 ± 0.533
0.846CysVal: 0.846 ± 0.895
0.423CysTrp: 0.423 ± 0.314
0.423CysTyr: 0.423 ± 0.409
0.0CysXaa: 0.0 ± 0.0
Asp
4.23AspAla: 4.23 ± 1.387
0.846AspCys: 0.846 ± 0.576
3.384AspAsp: 3.384 ± 1.361
4.653AspGlu: 4.653 ± 2.359
2.115AspPhe: 2.115 ± 0.427
2.115AspGly: 2.115 ± 0.697
2.115AspHis: 2.115 ± 0.659
5.499AspIle: 5.499 ± 3.511
3.384AspLys: 3.384 ± 1.401
6.345AspLeu: 6.345 ± 1.122
1.692AspMet: 1.692 ± 1.205
5.499AspAsn: 5.499 ± 1.354
3.807AspPro: 3.807 ± 1.782
1.692AspGln: 1.692 ± 0.695
1.692AspArg: 1.692 ± 0.708
6.345AspSer: 6.345 ± 2.145
2.115AspThr: 2.115 ± 1.415
5.499AspVal: 5.499 ± 1.401
0.846AspTrp: 0.846 ± 0.397
1.692AspTyr: 1.692 ± 0.652
0.0AspXaa: 0.0 ± 0.0
Glu
5.922GluAla: 5.922 ± 0.775
0.846GluCys: 0.846 ± 0.628
4.23GluAsp: 4.23 ± 0.858
6.345GluGlu: 6.345 ± 1.885
2.538GluPhe: 2.538 ± 0.974
4.23GluGly: 4.23 ± 1.5
0.423GluHis: 0.423 ± 0.448
3.384GluIle: 3.384 ± 0.987
2.115GluLys: 2.115 ± 0.61
3.384GluLeu: 3.384 ± 1.035
1.269GluMet: 1.269 ± 0.659
2.538GluAsn: 2.538 ± 1.063
2.961GluPro: 2.961 ± 1.073
5.499GluGln: 5.499 ± 0.715
4.23GluArg: 4.23 ± 1.004
4.23GluSer: 4.23 ± 0.714
2.961GluThr: 2.961 ± 0.736
2.538GluVal: 2.538 ± 1.873
1.269GluTrp: 1.269 ± 0.799
3.384GluTyr: 3.384 ± 0.923
0.0GluXaa: 0.0 ± 0.0
Phe
4.653PheAla: 4.653 ± 1.456
0.0PheCys: 0.0 ± 0.0
2.961PheAsp: 2.961 ± 0.57
2.538PheGlu: 2.538 ± 1.17
1.692PhePhe: 1.692 ± 0.795
3.384PheGly: 3.384 ± 0.987
0.423PheHis: 0.423 ± 0.314
2.961PheIle: 2.961 ± 1.316
2.115PheLys: 2.115 ± 0.775
4.23PheLeu: 4.23 ± 1.313
1.269PheMet: 1.269 ± 0.533
2.115PheAsn: 2.115 ± 1.041
1.692PhePro: 1.692 ± 0.501
3.807PheGln: 3.807 ± 0.605
2.115PheArg: 2.115 ± 0.764
2.538PheSer: 2.538 ± 1.468
0.846PheThr: 0.846 ± 0.421
3.807PheVal: 3.807 ± 1.001
2.115PheTrp: 2.115 ± 0.775
2.538PheTyr: 2.538 ± 0.537
0.0PheXaa: 0.0 ± 0.0
Gly
3.807GlyAla: 3.807 ± 1.415
1.269GlyCys: 1.269 ± 0.57
4.23GlyAsp: 4.23 ± 1.619
3.384GlyGlu: 3.384 ± 0.655
1.269GlyPhe: 1.269 ± 0.825
4.23GlyGly: 4.23 ± 1.995
2.115GlyHis: 2.115 ± 0.778
2.538GlyIle: 2.538 ± 1.162
2.538GlyLys: 2.538 ± 0.803
8.037GlyLeu: 8.037 ± 1.957
0.846GlyMet: 0.846 ± 0.834
2.538GlyAsn: 2.538 ± 1.017
2.115GlyPro: 2.115 ± 0.804
2.115GlyGln: 2.115 ± 1.041
5.499GlyArg: 5.499 ± 1.847
6.768GlySer: 6.768 ± 1.99
3.807GlyThr: 3.807 ± 1.455
4.23GlyVal: 4.23 ± 1.676
0.0GlyTrp: 0.0 ± 0.0
1.692GlyTyr: 1.692 ± 0.188
0.0GlyXaa: 0.0 ± 0.0
His
2.115HisAla: 2.115 ± 0.791
1.269HisCys: 1.269 ± 0.554
1.692HisAsp: 1.692 ± 0.585
1.269HisGlu: 1.269 ± 0.779
1.269HisPhe: 1.269 ± 0.732
0.423HisGly: 0.423 ± 0.375
0.423HisHis: 0.423 ± 0.314
0.846HisIle: 0.846 ± 0.421
0.423HisLys: 0.423 ± 0.409
0.846HisLeu: 0.846 ± 0.608
0.423HisMet: 0.423 ± 0.417
0.0HisAsn: 0.0 ± 0.0
1.692HisPro: 1.692 ± 0.659
0.423HisGln: 0.423 ± 0.314
1.692HisArg: 1.692 ± 0.929
2.115HisSer: 2.115 ± 0.659
0.846HisThr: 0.846 ± 0.397
1.692HisVal: 1.692 ± 0.925
0.423HisTrp: 0.423 ± 0.409
0.423HisTyr: 0.423 ± 0.314
0.0HisXaa: 0.0 ± 0.0
Ile
1.692IleAla: 1.692 ± 0.847
0.846IleCys: 0.846 ± 0.514
4.23IleAsp: 4.23 ± 1.34
4.23IleGlu: 4.23 ± 1.808
2.538IlePhe: 2.538 ± 0.987
4.23IleGly: 4.23 ± 3.357
0.846IleHis: 0.846 ± 0.421
3.807IleIle: 3.807 ± 2.035
2.115IleLys: 2.115 ± 0.346
4.23IleLeu: 4.23 ± 0.807
0.423IleMet: 0.423 ± 0.409
0.846IleAsn: 0.846 ± 0.397
1.692IlePro: 1.692 ± 1.096
2.961IleGln: 2.961 ± 0.901
2.961IleArg: 2.961 ± 1.36
2.961IleSer: 2.961 ± 0.547
3.807IleThr: 3.807 ± 2.006
4.653IleVal: 4.653 ± 1.092
0.846IleTrp: 0.846 ± 0.458
1.692IleTyr: 1.692 ± 0.861
0.0IleXaa: 0.0 ± 0.0
Lys
2.538LysAla: 2.538 ± 1.468
2.538LysCys: 2.538 ± 0.923
1.269LysAsp: 1.269 ± 0.583
2.115LysGlu: 2.115 ± 0.697
3.384LysPhe: 3.384 ± 1.006
2.538LysGly: 2.538 ± 1.348
0.423LysHis: 0.423 ± 0.314
4.23LysIle: 4.23 ± 1.019
2.961LysLys: 2.961 ± 1.189
0.846LysLeu: 0.846 ± 0.397
0.846LysMet: 0.846 ± 0.449
3.384LysAsn: 3.384 ± 0.808
0.423LysPro: 0.423 ± 0.314
1.269LysGln: 1.269 ± 0.411
5.076LysArg: 5.076 ± 0.563
2.961LysSer: 2.961 ± 1.35
2.961LysThr: 2.961 ± 0.833
4.23LysVal: 4.23 ± 1.109
0.423LysTrp: 0.423 ± 0.409
0.846LysTyr: 0.846 ± 0.421
0.0LysXaa: 0.0 ± 0.0
Leu
5.499LeuAla: 5.499 ± 0.89
1.692LeuCys: 1.692 ± 1.105
4.653LeuAsp: 4.653 ± 1.287
4.23LeuGlu: 4.23 ± 0.744
7.191LeuPhe: 7.191 ± 1.566
4.23LeuGly: 4.23 ± 0.846
1.692LeuHis: 1.692 ± 0.715
2.115LeuIle: 2.115 ± 0.771
4.653LeuLys: 4.653 ± 1.309
7.614LeuLeu: 7.614 ± 2.135
1.692LeuMet: 1.692 ± 0.714
2.538LeuAsn: 2.538 ± 0.978
5.499LeuPro: 5.499 ± 1.941
7.614LeuGln: 7.614 ± 1.791
5.076LeuArg: 5.076 ± 1.288
7.191LeuSer: 7.191 ± 1.283
3.807LeuThr: 3.807 ± 1.612
5.076LeuVal: 5.076 ± 1.467
0.423LeuTrp: 0.423 ± 0.409
3.384LeuTyr: 3.384 ± 0.844
0.0LeuXaa: 0.0 ± 0.0
Met
2.538MetAla: 2.538 ± 0.678
0.0MetCys: 0.0 ± 0.0
0.846MetAsp: 0.846 ± 0.458
1.692MetGlu: 1.692 ± 0.188
1.692MetPhe: 1.692 ± 0.717
0.423MetGly: 0.423 ± 0.417
0.0MetHis: 0.0 ± 0.0
0.846MetIle: 0.846 ± 0.628
1.692MetLys: 1.692 ± 0.847
1.692MetLeu: 1.692 ± 0.562
0.0MetMet: 0.0 ± 0.0
0.846MetAsn: 0.846 ± 0.397
0.846MetPro: 0.846 ± 0.449
0.0MetGln: 0.0 ± 0.0
0.846MetArg: 0.846 ± 0.397
2.538MetSer: 2.538 ± 0.905
0.423MetThr: 0.423 ± 0.445
1.269MetVal: 1.269 ± 0.583
0.0MetTrp: 0.0 ± 0.0
0.423MetTyr: 0.423 ± 0.417
0.0MetXaa: 0.0 ± 0.0
Asn
2.961AsnAla: 2.961 ± 1.05
0.0AsnCys: 0.0 ± 0.0
1.692AsnAsp: 1.692 ± 0.535
1.692AsnGlu: 1.692 ± 0.929
1.692AsnPhe: 1.692 ± 0.795
1.692AsnGly: 1.692 ± 0.922
2.115AsnHis: 2.115 ± 0.961
2.961AsnIle: 2.961 ± 0.979
2.115AsnLys: 2.115 ± 0.663
1.692AsnLeu: 1.692 ± 0.508
0.423AsnMet: 0.423 ± 0.417
4.23AsnAsn: 4.23 ± 0.992
2.538AsnPro: 2.538 ± 1.063
1.269AsnGln: 1.269 ± 0.583
2.115AsnArg: 2.115 ± 1.083
2.961AsnSer: 2.961 ± 1.481
4.23AsnThr: 4.23 ± 0.858
2.538AsnVal: 2.538 ± 0.586
0.423AsnTrp: 0.423 ± 0.417
0.846AsnTyr: 0.846 ± 0.608
0.0AsnXaa: 0.0 ± 0.0
Pro
5.076ProAla: 5.076 ± 0.981
0.423ProCys: 0.423 ± 0.448
5.922ProAsp: 5.922 ± 2.763
3.807ProGlu: 3.807 ± 0.893
2.115ProPhe: 2.115 ± 0.666
2.961ProGly: 2.961 ± 1.176
0.423ProHis: 0.423 ± 0.375
3.384ProIle: 3.384 ± 1.649
2.115ProLys: 2.115 ± 0.697
5.076ProLeu: 5.076 ± 1.474
0.423ProMet: 0.423 ± 0.314
1.692ProAsn: 1.692 ± 0.188
4.653ProPro: 4.653 ± 0.874
2.961ProGln: 2.961 ± 1.179
5.076ProArg: 5.076 ± 1.945
5.076ProSer: 5.076 ± 1.631
2.538ProThr: 2.538 ± 1.331
2.961ProVal: 2.961 ± 1.233
0.0ProTrp: 0.0 ± 0.0
1.269ProTyr: 1.269 ± 1.25
0.0ProXaa: 0.0 ± 0.0
Gln
1.269GlnAla: 1.269 ± 0.599
0.423GlnCys: 0.423 ± 0.448
3.807GlnAsp: 3.807 ± 0.67
2.115GlnGlu: 2.115 ± 0.61
2.538GlnPhe: 2.538 ± 0.83
2.538GlnGly: 2.538 ± 0.829
0.846GlnHis: 0.846 ± 0.519
1.692GlnIle: 1.692 ± 0.535
2.115GlnLys: 2.115 ± 0.775
4.653GlnLeu: 4.653 ± 2.004
1.269GlnMet: 1.269 ± 0.569
1.692GlnAsn: 1.692 ± 0.997
1.692GlnPro: 1.692 ± 0.708
0.846GlnGln: 0.846 ± 0.447
2.538GlnArg: 2.538 ± 1.23
2.538GlnSer: 2.538 ± 0.769
2.538GlnThr: 2.538 ± 1.503
2.961GlnVal: 2.961 ± 0.673
0.846GlnTrp: 0.846 ± 0.628
0.846GlnTyr: 0.846 ± 0.458
0.0GlnXaa: 0.0 ± 0.0
Arg
5.499ArgAla: 5.499 ± 1.123
1.269ArgCys: 1.269 ± 0.727
3.807ArgAsp: 3.807 ± 0.84
5.499ArgGlu: 5.499 ± 1.346
3.807ArgPhe: 3.807 ± 1.241
6.345ArgGly: 6.345 ± 1.106
2.538ArgHis: 2.538 ± 0.432
0.846ArgIle: 0.846 ± 0.749
3.807ArgLys: 3.807 ± 1.094
5.922ArgLeu: 5.922 ± 1.774
0.423ArgMet: 0.423 ± 0.417
1.692ArgAsn: 1.692 ± 1.323
6.345ArgPro: 6.345 ± 2.285
3.384ArgGln: 3.384 ± 0.607
5.922ArgArg: 5.922 ± 1.897
10.998ArgSer: 10.998 ± 7.602
3.384ArgThr: 3.384 ± 0.947
4.23ArgVal: 4.23 ± 1.424
0.0ArgTrp: 0.0 ± 0.0
1.692ArgTyr: 1.692 ± 0.717
0.0ArgXaa: 0.0 ± 0.0
Ser
2.538SerAla: 2.538 ± 1.097
1.269SerCys: 1.269 ± 0.533
5.922SerAsp: 5.922 ± 1.594
4.23SerGlu: 4.23 ± 1.319
3.384SerPhe: 3.384 ± 0.808
6.345SerGly: 6.345 ± 1.938
0.846SerHis: 0.846 ± 0.608
4.653SerIle: 4.653 ± 0.975
3.384SerLys: 3.384 ± 1.433
10.998SerLeu: 10.998 ± 2.132
2.538SerMet: 2.538 ± 0.627
2.115SerAsn: 2.115 ± 0.828
5.499SerPro: 5.499 ± 2.85
2.115SerGln: 2.115 ± 0.59
11.421SerArg: 11.421 ± 5.992
5.499SerSer: 5.499 ± 2.147
5.499SerThr: 5.499 ± 1.486
4.23SerVal: 4.23 ± 0.641
0.423SerTrp: 0.423 ± 0.314
0.423SerTyr: 0.423 ± 0.409
0.0SerXaa: 0.0 ± 0.0
Thr
2.115ThrAla: 2.115 ± 0.804
0.846ThrCys: 0.846 ± 0.552
3.384ThrAsp: 3.384 ± 0.375
3.384ThrGlu: 3.384 ± 0.828
1.269ThrPhe: 1.269 ± 0.411
5.922ThrGly: 5.922 ± 1.062
0.846ThrHis: 0.846 ± 0.749
2.961ThrIle: 2.961 ± 1.684
1.269ThrLys: 1.269 ± 0.823
3.807ThrLeu: 3.807 ± 1.64
2.115ThrMet: 2.115 ± 1.422
1.269ThrAsn: 1.269 ± 0.727
5.499ThrPro: 5.499 ± 2.312
0.846ThrGln: 0.846 ± 0.576
5.076ThrArg: 5.076 ± 1.837
2.961ThrSer: 2.961 ± 1.207
3.807ThrThr: 3.807 ± 0.795
5.499ThrVal: 5.499 ± 1.431
0.846ThrTrp: 0.846 ± 0.449
1.269ThrTyr: 1.269 ± 0.909
0.0ThrXaa: 0.0 ± 0.0
Val
2.538ValAla: 2.538 ± 0.42
1.692ValCys: 1.692 ± 1.028
5.922ValAsp: 5.922 ± 1.422
5.076ValGlu: 5.076 ± 1.824
1.692ValPhe: 1.692 ± 0.501
5.076ValGly: 5.076 ± 1.337
1.692ValHis: 1.692 ± 0.69
2.115ValIle: 2.115 ± 0.698
2.961ValLys: 2.961 ± 1.031
2.538ValLeu: 2.538 ± 1.906
0.423ValMet: 0.423 ± 0.409
3.384ValAsn: 3.384 ± 0.992
5.076ValPro: 5.076 ± 1.568
0.846ValGln: 0.846 ± 0.421
6.768ValArg: 6.768 ± 0.885
7.191ValSer: 7.191 ± 0.855
2.961ValThr: 2.961 ± 0.409
2.538ValVal: 2.538 ± 1.152
1.269ValTrp: 1.269 ± 0.902
1.692ValTyr: 1.692 ± 0.621
0.0ValXaa: 0.0 ± 0.0
Trp
0.846TrpAla: 0.846 ± 0.397
0.423TrpCys: 0.423 ± 0.314
1.692TrpAsp: 1.692 ± 1.205
0.0TrpGlu: 0.0 ± 0.0
0.423TrpPhe: 0.423 ± 0.409
0.0TrpGly: 0.0 ± 0.0
1.692TrpHis: 1.692 ± 0.893
0.846TrpIle: 0.846 ± 0.628
0.423TrpLys: 0.423 ± 0.314
1.692TrpLeu: 1.692 ± 0.695
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.423TrpGln: 0.423 ± 0.314
0.423TrpArg: 0.423 ± 0.417
0.846TrpSer: 0.846 ± 0.447
1.269TrpThr: 1.269 ± 0.799
0.846TrpVal: 0.846 ± 0.449
0.0TrpTrp: 0.0 ± 0.0
0.846TrpTyr: 0.846 ± 0.628
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.269TyrAla: 1.269 ± 0.533
0.423TyrCys: 0.423 ± 0.445
1.269TyrAsp: 1.269 ± 0.578
1.692TyrGlu: 1.692 ± 0.501
2.538TyrPhe: 2.538 ± 0.96
1.692TyrGly: 1.692 ± 0.709
0.423TyrHis: 0.423 ± 0.417
1.692TyrIle: 1.692 ± 1.183
1.269TyrLys: 1.269 ± 0.583
2.538TyrLeu: 2.538 ± 0.678
1.269TyrMet: 1.269 ± 0.674
1.692TyrAsn: 1.692 ± 0.621
0.846TyrPro: 0.846 ± 0.458
0.423TyrGln: 0.423 ± 0.314
2.961TyrArg: 2.961 ± 1.16
0.846TyrSer: 0.846 ± 0.498
1.692TyrThr: 1.692 ± 0.709
0.846TyrVal: 0.846 ± 0.458
0.846TyrTrp: 0.846 ± 0.834
0.846TyrTyr: 0.846 ± 0.498
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2365 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski