Amino acid dipepetide frequency for Lactonifactor longoviformis DSM 17459

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.347AlaAla: 8.347 ± 0.117	1.207AlaCys: 1.207 ± 0.032	4.385AlaAsp: 4.385 ± 0.059	5.574AlaGlu: 5.574 ± 0.073	3.219AlaPhe: 3.219 ± 0.065	7.008AlaGly: 7.008 ± 0.08	1.11AlaHis: 1.11 ± 0.028	4.773AlaIle: 4.773 ± 0.065	4.316AlaLys: 4.316 ± 0.059	7.344AlaLeu: 7.344 ± 0.09	2.522AlaMet: 2.522 ± 0.051	2.36AlaAsn: 2.36 ± 0.042	2.227AlaPro: 2.227 ± 0.043	2.298AlaGln: 2.298 ± 0.043	3.266AlaArg: 3.266 ± 0.056	4.228AlaSer: 4.228 ± 0.062	2.929AlaThr: 2.929 ± 0.057	7.058AlaVal: 7.058 ± 0.073	0.668AlaTrp: 0.668 ± 0.022	2.815AlaTyr: 2.815 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	1.066CysAla: 1.066 ± 0.03	0.31CysCys: 0.31 ± 0.015	0.772CysAsp: 0.772 ± 0.025	0.924CysGlu: 0.924 ± 0.027	0.626CysPhe: 0.626 ± 0.022	1.596CysGly: 1.596 ± 0.04	0.306CysHis: 0.306 ± 0.014	1.153CysIle: 1.153 ± 0.033	0.74CysLys: 0.74 ± 0.026	1.279CysLeu: 1.279 ± 0.034	0.49CysMet: 0.49 ± 0.021	0.525CysAsn: 0.525 ± 0.023	0.703CysPro: 0.703 ± 0.029	0.468CysGln: 0.468 ± 0.02	1.023CysArg: 1.023 ± 0.029	1.015CysSer: 1.015 ± 0.028	0.817CysThr: 0.817 ± 0.024	1.024CysVal: 1.024 ± 0.032	0.135CysTrp: 0.135 ± 0.009	0.582CysTyr: 0.582 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	3.983AspAla: 3.983 ± 0.062	0.818AspCys: 0.818 ± 0.026	2.272AspAsp: 2.272 ± 0.053	3.994AspGlu: 3.994 ± 0.055	2.306AspPhe: 2.306 ± 0.039	4.359AspGly: 4.359 ± 0.08	0.789AspHis: 0.789 ± 0.023	4.226AspIle: 4.226 ± 0.052	3.305AspLys: 3.305 ± 0.054	4.333AspLeu: 4.333 ± 0.057	1.768AspMet: 1.768 ± 0.033	1.981AspAsn: 1.981 ± 0.04	1.914AspPro: 1.914 ± 0.041	1.233AspGln: 1.233 ± 0.029	2.531AspArg: 2.531 ± 0.045	3.057AspSer: 3.057 ± 0.051	3.248AspThr: 3.248 ± 0.051	3.39AspVal: 3.39 ± 0.059	0.589AspTrp: 0.589 ± 0.021	2.478AspTyr: 2.478 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	6.066GluAla: 6.066 ± 0.08	0.832GluCys: 0.832 ± 0.024	4.423GluAsp: 4.423 ± 0.059	7.971GluGlu: 7.971 ± 0.09	2.529GluPhe: 2.529 ± 0.044	4.869GluGly: 4.869 ± 0.065	1.389GluHis: 1.389 ± 0.037	5.754GluIle: 5.754 ± 0.064	6.354GluLys: 6.354 ± 0.068	6.866GluLeu: 6.866 ± 0.07	2.42GluMet: 2.42 ± 0.043	3.668GluAsn: 3.668 ± 0.052	2.009GluPro: 2.009 ± 0.044	2.914GluGln: 2.914 ± 0.044	3.514GluArg: 3.514 ± 0.053	3.33GluSer: 3.33 ± 0.049	3.8GluThr: 3.8 ± 0.054	4.545GluVal: 4.545 ± 0.058	0.696GluTrp: 0.696 ± 0.026	3.149GluTyr: 3.149 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	3.003PheAla: 3.003 ± 0.049	0.767PheCys: 0.767 ± 0.026	2.196PheAsp: 2.196 ± 0.048	2.341PheGlu: 2.341 ± 0.04	1.737PhePhe: 1.737 ± 0.037	3.016PheGly: 3.016 ± 0.056	0.829PheHis: 0.829 ± 0.022	2.696PheIle: 2.696 ± 0.051	1.718PheLys: 1.718 ± 0.036	4.078PheLeu: 4.078 ± 0.065	1.187PheMet: 1.187 ± 0.027	1.261PheAsn: 1.261 ± 0.033	1.456PhePro: 1.456 ± 0.031	1.513PheGln: 1.513 ± 0.037	1.789PheArg: 1.789 ± 0.039	2.828PheSer: 2.828 ± 0.042	2.369PheThr: 2.369 ± 0.038	2.63PheVal: 2.63 ± 0.048	0.43PheTrp: 0.43 ± 0.017	1.668PheTyr: 1.668 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	5.6GlyAla: 5.6 ± 0.076	1.471GlyCys: 1.471 ± 0.036	3.688GlyAsp: 3.688 ± 0.052	5.446GlyGlu: 5.446 ± 0.073	3.161GlyPhe: 3.161 ± 0.046	5.644GlyGly: 5.644 ± 0.091	1.258GlyHis: 1.258 ± 0.032	6.893GlyIle: 6.893 ± 0.076	5.466GlyLys: 5.466 ± 0.063	6.307GlyLeu: 6.307 ± 0.08	2.678GlyMet: 2.678 ± 0.042	3.143GlyAsn: 3.143 ± 0.059	1.501GlyPro: 1.501 ± 0.032	2.241GlyGln: 2.241 ± 0.042	3.47GlyArg: 3.47 ± 0.057	4.393GlySer: 4.393 ± 0.067	4.575GlyThr: 4.575 ± 0.068	5.254GlyVal: 5.254 ± 0.063	1.007GlyTrp: 1.007 ± 0.05	3.541GlyTyr: 3.541 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.075HisAla: 1.075 ± 0.027	0.286HisCys: 0.286 ± 0.015	0.766HisAsp: 0.766 ± 0.025	1.04HisGlu: 1.04 ± 0.029	0.789HisPhe: 0.789 ± 0.021	1.243HisGly: 1.243 ± 0.035	0.404HisHis: 0.404 ± 0.021	1.307HisIle: 1.307 ± 0.034	0.939HisLys: 0.939 ± 0.027	1.582HisLeu: 1.582 ± 0.039	0.604HisMet: 0.604 ± 0.022	0.673HisAsn: 0.673 ± 0.022	0.899HisPro: 0.899 ± 0.023	0.55HisGln: 0.55 ± 0.02	0.897HisArg: 0.897 ± 0.025	0.964HisSer: 0.964 ± 0.024	1.011HisThr: 1.011 ± 0.028	1.057HisVal: 1.057 ± 0.03	0.205HisTrp: 0.205 ± 0.012	0.709HisTyr: 0.709 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.765IleAla: 5.765 ± 0.074	1.324IleCys: 1.324 ± 0.036	3.684IleAsp: 3.684 ± 0.053	4.501IleGlu: 4.501 ± 0.058	2.888IlePhe: 2.888 ± 0.054	5.214IleGly: 5.214 ± 0.069	1.364IleHis: 1.364 ± 0.026	4.889IleIle: 4.889 ± 0.077	3.777IleLys: 3.777 ± 0.052	7.522IleLeu: 7.522 ± 0.09	1.997IleMet: 1.997 ± 0.038	2.488IleAsn: 2.488 ± 0.04	3.433IlePro: 3.433 ± 0.053	2.548IleGln: 2.548 ± 0.044	3.702IleArg: 3.702 ± 0.05	4.706IleSer: 4.706 ± 0.068	4.255IleThr: 4.255 ± 0.053	4.636IleVal: 4.636 ± 0.067	0.628IleTrp: 0.628 ± 0.021	2.665IleTyr: 2.665 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	4.939LysAla: 4.939 ± 0.066	0.665LysCys: 0.665 ± 0.022	3.581LysAsp: 3.581 ± 0.057	6.555LysGlu: 6.555 ± 0.077	1.607LysPhe: 1.607 ± 0.034	4.454LysGly: 4.454 ± 0.068	0.842LysHis: 0.842 ± 0.027	4.457LysIle: 4.457 ± 0.062	5.542LysLys: 5.542 ± 0.07	5.043LysLeu: 5.043 ± 0.059	1.987LysMet: 1.987 ± 0.038	2.969LysAsn: 2.969 ± 0.044	1.962LysPro: 1.962 ± 0.041	2.073LysGln: 2.073 ± 0.035	3.028LysArg: 3.028 ± 0.05	3.158LysSer: 3.158 ± 0.051	3.534LysThr: 3.534 ± 0.054	4.132LysVal: 4.132 ± 0.059	0.583LysTrp: 0.583 ± 0.019	2.545LysTyr: 2.545 ± 0.046	0.0LysXaa: 0.0 ± 0.0
Leu	7.126LeuAla: 7.126 ± 0.068	1.619LeuCys: 1.619 ± 0.037	4.965LeuAsp: 4.965 ± 0.065	7.024LeuGlu: 7.024 ± 0.079	3.797LeuPhe: 3.797 ± 0.061	6.842LeuGly: 6.842 ± 0.078	1.556LeuHis: 1.556 ± 0.033	5.964LeuIle: 5.964 ± 0.086	5.917LeuLys: 5.917 ± 0.071	9.248LeuLeu: 9.248 ± 0.117	2.741LeuMet: 2.741 ± 0.048	3.471LeuAsn: 3.471 ± 0.056	3.829LeuPro: 3.829 ± 0.055	2.979LeuGln: 2.979 ± 0.05	4.067LeuArg: 4.067 ± 0.063	6.248LeuSer: 6.248 ± 0.079	5.351LeuThr: 5.351 ± 0.065	5.533LeuVal: 5.533 ± 0.071	0.81LeuTrp: 0.81 ± 0.03	3.346LeuTyr: 3.346 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.72MetAla: 2.72 ± 0.046	0.372MetCys: 0.372 ± 0.016	1.838MetAsp: 1.838 ± 0.036	2.75MetGlu: 2.75 ± 0.045	0.972MetPhe: 0.972 ± 0.03	2.412MetGly: 2.412 ± 0.043	0.486MetHis: 0.486 ± 0.019	2.136MetIle: 2.136 ± 0.041	2.415MetLys: 2.415 ± 0.04	2.716MetLeu: 2.716 ± 0.045	0.905MetMet: 0.905 ± 0.028	1.565MetAsn: 1.565 ± 0.033	1.149MetPro: 1.149 ± 0.033	1.006MetGln: 1.006 ± 0.029	1.319MetArg: 1.319 ± 0.032	1.75MetSer: 1.75 ± 0.037	1.756MetThr: 1.756 ± 0.036	1.97MetVal: 1.97 ± 0.039	0.224MetTrp: 0.224 ± 0.011	0.906MetTyr: 0.906 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.863AsnAla: 2.863 ± 0.051	0.635AsnCys: 0.635 ± 0.022	1.713AsnAsp: 1.713 ± 0.039	2.357AsnGlu: 2.357 ± 0.043	1.448AsnPhe: 1.448 ± 0.029	3.202AsnGly: 3.202 ± 0.061	0.774AsnHis: 0.774 ± 0.024	3.018AsnIle: 3.018 ± 0.05	2.207AsnLys: 2.207 ± 0.042	3.554AsnLeu: 3.554 ± 0.051	1.27AsnMet: 1.27 ± 0.031	1.499AsnAsn: 1.499 ± 0.037	2.011AsnPro: 2.011 ± 0.041	1.471AsnGln: 1.471 ± 0.032	1.942AsnArg: 1.942 ± 0.041	2.216AsnSer: 2.216 ± 0.043	2.239AsnThr: 2.239 ± 0.048	2.419AsnVal: 2.419 ± 0.043	0.402AsnTrp: 0.402 ± 0.017	1.681AsnTyr: 1.681 ± 0.039	0.001AsnXaa: 0.001 ± 0.001
Pro	2.684ProAla: 2.684 ± 0.048	0.546ProCys: 0.546 ± 0.019	2.415ProAsp: 2.415 ± 0.048	3.456ProGlu: 3.456 ± 0.061	1.578ProPhe: 1.578 ± 0.032	2.987ProGly: 2.987 ± 0.043	0.602ProHis: 0.602 ± 0.022	2.038ProIle: 2.038 ± 0.037	1.844ProLys: 1.844 ± 0.04	3.011ProLeu: 3.011 ± 0.053	0.974ProMet: 0.974 ± 0.027	1.222ProAsn: 1.222 ± 0.034	0.964ProPro: 0.964 ± 0.029	1.183ProGln: 1.183 ± 0.033	1.328ProArg: 1.328 ± 0.033	1.909ProSer: 1.909 ± 0.035	1.553ProThr: 1.553 ± 0.032	3.23ProVal: 3.23 ± 0.053	0.374ProTrp: 0.374 ± 0.016	1.538ProTyr: 1.538 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.567GlnAla: 2.567 ± 0.041	0.365GlnCys: 0.365 ± 0.018	1.591GlnAsp: 1.591 ± 0.035	2.987GlnGlu: 2.987 ± 0.055	1.086GlnPhe: 1.086 ± 0.026	2.37GlnGly: 2.37 ± 0.036	0.454GlnHis: 0.454 ± 0.019	2.526GlnIle: 2.526 ± 0.045	2.625GlnLys: 2.625 ± 0.048	2.866GlnLeu: 2.866 ± 0.048	1.209GlnMet: 1.209 ± 0.03	1.457GlnAsn: 1.457 ± 0.035	0.984GlnPro: 0.984 ± 0.025	1.13GlnGln: 1.13 ± 0.032	1.491GlnArg: 1.491 ± 0.04	1.68GlnSer: 1.68 ± 0.037	1.713GlnThr: 1.713 ± 0.038	2.219GlnVal: 2.219 ± 0.04	0.372GlnTrp: 0.372 ± 0.018	1.299GlnTyr: 1.299 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	2.927ArgAla: 2.927 ± 0.052	0.601ArgCys: 0.601 ± 0.021	2.439ArgAsp: 2.439 ± 0.046	4.767ArgGlu: 4.767 ± 0.065	1.809ArgPhe: 1.809 ± 0.036	2.9ArgGly: 2.9 ± 0.044	0.803ArgHis: 0.803 ± 0.026	3.667ArgIle: 3.667 ± 0.052	3.392ArgLys: 3.392 ± 0.053	4.19ArgLeu: 4.19 ± 0.064	1.717ArgMet: 1.717 ± 0.036	1.944ArgAsn: 1.944 ± 0.038	1.401ArgPro: 1.401 ± 0.033	1.871ArgGln: 1.871 ± 0.044	2.549ArgArg: 2.549 ± 0.05	2.125ArgSer: 2.125 ± 0.039	2.265ArgThr: 2.265 ± 0.043	2.766ArgVal: 2.766 ± 0.046	0.472ArgTrp: 0.472 ± 0.017	1.904ArgTyr: 1.904 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.204SerAla: 4.204 ± 0.06	0.937SerCys: 0.937 ± 0.025	2.86SerAsp: 2.86 ± 0.047	3.534SerGlu: 3.534 ± 0.053	2.647SerPhe: 2.647 ± 0.048	5.21SerGly: 5.21 ± 0.08	1.044SerHis: 1.044 ± 0.029	4.027SerIle: 4.027 ± 0.057	3.037SerLys: 3.037 ± 0.049	5.434SerLeu: 5.434 ± 0.06	1.85SerMet: 1.85 ± 0.033	2.069SerAsn: 2.069 ± 0.04	2.093SerPro: 2.093 ± 0.038	1.991SerGln: 1.991 ± 0.044	2.95SerArg: 2.95 ± 0.046	3.743SerSer: 3.743 ± 0.067	2.72SerThr: 2.72 ± 0.046	4.432SerVal: 4.432 ± 0.058	0.596SerTrp: 0.596 ± 0.02	2.397SerTyr: 2.397 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	4.762ThrAla: 4.762 ± 0.07	0.705ThrCys: 0.705 ± 0.022	2.89ThrAsp: 2.89 ± 0.054	3.756ThrGlu: 3.756 ± 0.061	2.143ThrPhe: 2.143 ± 0.039	5.153ThrGly: 5.153 ± 0.07	0.836ThrHis: 0.836 ± 0.025	3.802ThrIle: 3.802 ± 0.049	2.844ThrLys: 2.844 ± 0.048	4.992ThrLeu: 4.992 ± 0.064	1.451ThrMet: 1.451 ± 0.03	1.754ThrAsn: 1.754 ± 0.04	2.386ThrPro: 2.386 ± 0.042	1.5ThrGln: 1.5 ± 0.033	2.102ThrArg: 2.102 ± 0.037	2.942ThrSer: 2.942 ± 0.056	2.561ThrThr: 2.561 ± 0.052	4.456ThrVal: 4.456 ± 0.07	0.669ThrTrp: 0.669 ± 0.039	2.064ThrTyr: 2.064 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	4.572ValAla: 4.572 ± 0.063	1.288ValCys: 1.288 ± 0.032	3.375ValAsp: 3.375 ± 0.054	4.38ValGlu: 4.38 ± 0.066	2.979ValPhe: 2.979 ± 0.052	4.403ValGly: 4.403 ± 0.053	1.131ValHis: 1.131 ± 0.027	5.184ValIle: 5.184 ± 0.066	4.304ValLys: 4.304 ± 0.052	7.0ValLeu: 7.0 ± 0.074	2.169ValMet: 2.169 ± 0.037	2.826ValAsn: 2.826 ± 0.048	2.705ValPro: 2.705 ± 0.046	2.034ValGln: 2.034 ± 0.039	3.027ValArg: 3.027 ± 0.044	4.586ValSer: 4.586 ± 0.056	4.277ValThr: 4.277 ± 0.065	4.508ValVal: 4.508 ± 0.059	0.713ValTrp: 0.713 ± 0.027	2.737ValTyr: 2.737 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.585TrpAla: 0.585 ± 0.022	0.141TrpCys: 0.141 ± 0.011	0.547TrpAsp: 0.547 ± 0.02	0.83TrpGlu: 0.83 ± 0.026	0.415TrpPhe: 0.415 ± 0.016	0.752TrpGly: 0.752 ± 0.021	0.153TrpHis: 0.153 ± 0.01	0.764TrpIle: 0.764 ± 0.023	0.75TrpLys: 0.75 ± 0.024	0.937TrpLeu: 0.937 ± 0.032	0.34TrpMet: 0.34 ± 0.019	0.501TrpAsn: 0.501 ± 0.018	0.256TrpPro: 0.256 ± 0.015	0.348TrpGln: 0.348 ± 0.019	0.407TrpArg: 0.407 ± 0.019	0.502TrpSer: 0.502 ± 0.022	0.479TrpThr: 0.479 ± 0.019	0.568TrpVal: 0.568 ± 0.021	0.122TrpTrp: 0.122 ± 0.01	0.643TrpTyr: 0.643 ± 0.048	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.8TyrAla: 2.8 ± 0.049	0.669TyrCys: 0.669 ± 0.023	2.175TyrAsp: 2.175 ± 0.041	2.91TyrGlu: 2.91 ± 0.043	1.772TyrPhe: 1.772 ± 0.037	3.104TyrGly: 3.104 ± 0.051	0.872TyrHis: 0.872 ± 0.022	2.71TyrIle: 2.71 ± 0.05	2.161TyrLys: 2.161 ± 0.044	4.132TyrLeu: 4.132 ± 0.067	1.084TyrMet: 1.084 ± 0.027	1.544TyrAsn: 1.544 ± 0.038	1.556TyrPro: 1.556 ± 0.032	1.642TyrGln: 1.642 ± 0.038	2.105TyrArg: 2.105 ± 0.041	2.395TyrSer: 2.395 ± 0.047	2.317TyrThr: 2.317 ± 0.043	2.374TyrVal: 2.374 ± 0.041	0.345TyrTrp: 0.345 ± 0.016	2.128TyrTyr: 2.128 ± 0.056	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.001	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 4380 proteins (1447804 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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