Echinococcus multilocularis (Fox tapeworm)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda; Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus

Average proteome isoelectric point is 6.89

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10472 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A068XVC5|A0A068XVC5_ECHMU Forkhead box protein P4 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000320300 PE=4 SV=1
MM1 pKa = 7.54EE2 pKa = 6.48FIHH5 pKa = 6.83CEE7 pKa = 3.87KK8 pKa = 10.82NPTSDD13 pKa = 3.28VVKK16 pKa = 10.65SLEE19 pKa = 3.58EE20 pKa = 4.09LYY22 pKa = 10.66RR23 pKa = 11.84VEE25 pKa = 4.21TLVQIPEE32 pKa = 4.17WDD34 pKa = 3.58DD35 pKa = 2.96MGYY38 pKa = 10.75EE39 pKa = 4.3DD40 pKa = 5.08WHH42 pKa = 7.25ACNQPPQDD50 pKa = 4.38PNCEE54 pKa = 4.39VIPDD58 pKa = 3.67IAVDD62 pKa = 3.85ANVDD66 pKa = 4.38SIFGDD71 pKa = 3.53

Molecular weight: 8.15 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A087VYH0|A0A087VYH0_ECHMU Metaxin 1 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000092500 PE=3 SV=1
MM1 pKa = 7.66LGQLTRR7 pKa = 11.84RR8 pKa = 11.84HH9 pKa = 5.71HH10 pKa = 6.63RR11 pKa = 11.84PRR13 pKa = 11.84DD14 pKa = 3.8TPHH17 pKa = 6.5EE18 pKa = 4.2ACAADD23 pKa = 4.19RR24 pKa = 11.84FLHH27 pKa = 6.81ASTGKK32 pKa = 10.12NSNTISRR39 pKa = 11.84DD40 pKa = 3.35MIGVQRR46 pKa = 11.84LMLFIAILRR55 pKa = 11.84VFVLPTIHH63 pKa = 6.2FTRR66 pKa = 11.84SASLLLQFILAVFALFVLHH85 pKa = 6.44YY86 pKa = 10.6LSLLLSTHH94 pKa = 5.45VEE96 pKa = 4.22RR97 pKa = 11.84PKK99 pKa = 10.39HH100 pKa = 5.67RR101 pKa = 11.84EE102 pKa = 3.4RR103 pKa = 11.84KK104 pKa = 9.31EE105 pKa = 3.71FMEE108 pKa = 4.07MKK110 pKa = 9.91VRR112 pKa = 11.84PEE114 pKa = 4.18SLPSPPPACFSHH126 pKa = 8.45LDD128 pKa = 3.31ILRR131 pKa = 11.84SQIHH135 pKa = 6.75LSPFSSSSSCVILRR149 pKa = 11.84QCHH152 pKa = 5.18FAHH155 pKa = 6.8PRR157 pKa = 11.84PHH159 pKa = 7.31LFTLSSQFTPEE170 pKa = 4.57SEE172 pKa = 4.2DD173 pKa = 3.15SLYY176 pKa = 11.17ASSIAEE182 pKa = 3.85TDD184 pKa = 2.99SRR186 pKa = 11.84GGIKK190 pKa = 10.05RR191 pKa = 11.84GRR193 pKa = 11.84KK194 pKa = 9.11AGFVADD200 pKa = 3.87AVTPVISGNYY210 pKa = 8.85CSSPPKK216 pKa = 10.27LRR218 pKa = 11.84LNHH221 pKa = 6.81PYY223 pKa = 10.5SLSSGVNNHH232 pKa = 5.67GQVQRR237 pKa = 11.84EE238 pKa = 3.86NQRR241 pKa = 11.84RR242 pKa = 11.84NRR244 pKa = 11.84VIKK247 pKa = 10.54RR248 pKa = 11.84NEE250 pKa = 4.01GVVKK254 pKa = 10.7SS255 pKa = 3.91

Molecular weight: 28.81 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

10470

2

10472

5200134

8

11193

496.6

55.23

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.479 ± 0.023

2.154 ± 0.017

4.968 ± 0.018

6.204 ± 0.028

3.952 ± 0.015

5.79 ± 0.027

2.527 ± 0.012

4.852 ± 0.016

4.757 ± 0.024

9.827 ± 0.032

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.118 ± 0.01

3.99 ± 0.013

5.849 ± 0.028

4.006 ± 0.018

6.286 ± 0.018

9.169 ± 0.033

5.964 ± 0.022

6.381 ± 0.017

1.099 ± 0.007

2.628 ± 0.013
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski