Amino acid dipepetide frequency for Feline herpesvirus 1 (FeHV-1) (Feline viral rhinotracheitis virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.628AlaAla: 5.628 ± 0.537
1.387AlaCys: 1.387 ± 0.186
3.334AlaAsp: 3.334 ± 0.324
3.067AlaGlu: 3.067 ± 0.315
2.587AlaPhe: 2.587 ± 0.264
3.387AlaGly: 3.387 ± 0.349
1.6AlaHis: 1.6 ± 0.201
4.908AlaIle: 4.908 ± 0.452
1.92AlaLys: 1.92 ± 0.272
7.255AlaLeu: 7.255 ± 0.554
1.334AlaMet: 1.334 ± 0.184
2.481AlaAsn: 2.481 ± 0.234
3.227AlaPro: 3.227 ± 0.343
1.894AlaGln: 1.894 ± 0.22
4.401AlaArg: 4.401 ± 0.281
5.468AlaSer: 5.468 ± 0.339
4.614AlaThr: 4.614 ± 0.354
4.774AlaVal: 4.774 ± 0.416
0.613AlaTrp: 0.613 ± 0.133
2.747AlaTyr: 2.747 ± 0.223
0.0AlaXaa: 0.0 ± 0.0
Cys
1.227CysAla: 1.227 ± 0.171
0.427CysCys: 0.427 ± 0.098
1.414CysAsp: 1.414 ± 0.256
0.854CysGlu: 0.854 ± 0.146
0.693CysPhe: 0.693 ± 0.121
1.307CysGly: 1.307 ± 0.178
0.64CysHis: 0.64 ± 0.124
1.52CysIle: 1.52 ± 0.228
0.72CysLys: 0.72 ± 0.133
2.0CysLeu: 2.0 ± 0.253
0.533CysMet: 0.533 ± 0.143
0.88CysAsn: 0.88 ± 0.198
0.934CysPro: 0.934 ± 0.191
0.453CysGln: 0.453 ± 0.103
1.04CysArg: 1.04 ± 0.159
0.934CysSer: 0.934 ± 0.157
1.414CysThr: 1.414 ± 0.196
1.414CysVal: 1.414 ± 0.21
0.293CysTrp: 0.293 ± 0.097
0.774CysTyr: 0.774 ± 0.161
0.0CysXaa: 0.0 ± 0.0
Asp
3.548AspAla: 3.548 ± 0.353
1.014AspCys: 1.014 ± 0.188
3.628AspAsp: 3.628 ± 0.393
3.467AspGlu: 3.467 ± 0.289
2.054AspPhe: 2.054 ± 0.259
4.348AspGly: 4.348 ± 0.365
1.627AspHis: 1.627 ± 0.245
4.214AspIle: 4.214 ± 0.374
1.734AspLys: 1.734 ± 0.272
5.788AspLeu: 5.788 ± 0.445
1.787AspMet: 1.787 ± 0.218
1.84AspAsn: 1.84 ± 0.276
3.494AspPro: 3.494 ± 0.36
1.174AspGln: 1.174 ± 0.193
3.307AspArg: 3.307 ± 0.27
4.641AspSer: 4.641 ± 0.474
3.761AspThr: 3.761 ± 0.313
4.054AspVal: 4.054 ± 0.412
0.72AspTrp: 0.72 ± 0.13
1.707AspTyr: 1.707 ± 0.227
0.0AspXaa: 0.0 ± 0.0
Glu
4.081GluAla: 4.081 ± 0.366
1.28GluCys: 1.28 ± 0.187
3.307GluAsp: 3.307 ± 0.351
2.881GluGlu: 2.881 ± 0.373
1.867GluPhe: 1.867 ± 0.238
2.881GluGly: 2.881 ± 0.267
1.2GluHis: 1.2 ± 0.197
2.534GluIle: 2.534 ± 0.254
1.92GluLys: 1.92 ± 0.273
4.961GluLeu: 4.961 ± 0.368
1.334GluMet: 1.334 ± 0.205
2.187GluAsn: 2.187 ± 0.227
2.294GluPro: 2.294 ± 0.248
1.254GluGln: 1.254 ± 0.196
3.361GluArg: 3.361 ± 0.287
3.628GluSer: 3.628 ± 0.323
4.401GluThr: 4.401 ± 0.343
3.201GluVal: 3.201 ± 0.305
0.373GluTrp: 0.373 ± 0.087
1.6GluTyr: 1.6 ± 0.193
0.0GluXaa: 0.0 ± 0.0
Phe
1.52PheAla: 1.52 ± 0.211
0.88PheCys: 0.88 ± 0.17
2.721PheAsp: 2.721 ± 0.291
2.027PheGlu: 2.027 ± 0.204
2.054PhePhe: 2.054 ± 0.28
2.374PheGly: 2.374 ± 0.256
1.094PheHis: 1.094 ± 0.148
2.987PheIle: 2.987 ± 0.291
1.947PheLys: 1.947 ± 0.276
3.654PheLeu: 3.654 ± 0.345
0.96PheMet: 0.96 ± 0.165
1.68PheAsn: 1.68 ± 0.244
1.867PhePro: 1.867 ± 0.229
0.96PheGln: 0.96 ± 0.125
2.134PheArg: 2.134 ± 0.215
3.467PheSer: 3.467 ± 0.377
2.587PheThr: 2.587 ± 0.307
2.214PheVal: 2.214 ± 0.312
0.347PheTrp: 0.347 ± 0.105
1.414PheTyr: 1.414 ± 0.224
0.0PheXaa: 0.0 ± 0.0
Gly
3.894GlyAla: 3.894 ± 0.315
1.067GlyCys: 1.067 ± 0.243
4.374GlyAsp: 4.374 ± 0.317
3.494GlyGlu: 3.494 ± 0.239
2.401GlyPhe: 2.401 ± 0.242
4.641GlyGly: 4.641 ± 0.568
1.387GlyHis: 1.387 ± 0.158
4.668GlyIle: 4.668 ± 0.406
2.0GlyLys: 2.0 ± 0.21
5.681GlyLeu: 5.681 ± 0.328
1.6GlyMet: 1.6 ± 0.187
2.401GlyAsn: 2.401 ± 0.336
2.667GlyPro: 2.667 ± 0.417
1.494GlyGln: 1.494 ± 0.191
4.054GlyArg: 4.054 ± 0.315
5.468GlySer: 5.468 ± 0.355
3.094GlyThr: 3.094 ± 0.268
4.268GlyVal: 4.268 ± 0.411
0.587GlyTrp: 0.587 ± 0.133
2.0GlyTyr: 2.0 ± 0.244
0.0GlyXaa: 0.0 ± 0.0
His
1.707HisAla: 1.707 ± 0.218
0.427HisCys: 0.427 ± 0.113
1.094HisAsp: 1.094 ± 0.182
1.174HisGlu: 1.174 ± 0.177
0.8HisPhe: 0.8 ± 0.178
1.814HisGly: 1.814 ± 0.21
0.934HisHis: 0.934 ± 0.177
1.76HisIle: 1.76 ± 0.191
0.8HisLys: 0.8 ± 0.147
2.961HisLeu: 2.961 ± 0.267
0.533HisMet: 0.533 ± 0.111
1.014HisAsn: 1.014 ± 0.149
2.401HisPro: 2.401 ± 0.24
1.334HisGln: 1.334 ± 0.208
1.894HisArg: 1.894 ± 0.238
1.92HisSer: 1.92 ± 0.224
1.867HisThr: 1.867 ± 0.208
1.414HisVal: 1.414 ± 0.195
0.053HisTrp: 0.053 ± 0.04
0.854HisTyr: 0.854 ± 0.165
0.0HisXaa: 0.0 ± 0.0
Ile
4.214IleAla: 4.214 ± 0.351
1.36IleCys: 1.36 ± 0.234
3.788IleAsp: 3.788 ± 0.511
3.681IleGlu: 3.681 ± 0.377
3.147IlePhe: 3.147 ± 0.368
3.628IleGly: 3.628 ± 0.317
2.027IleHis: 2.027 ± 0.182
4.268IleIle: 4.268 ± 0.431
2.321IleLys: 2.321 ± 0.262
5.975IleLeu: 5.975 ± 0.396
1.307IleMet: 1.307 ± 0.219
3.094IleAsn: 3.094 ± 0.356
3.628IlePro: 3.628 ± 0.32
2.881IleGln: 2.881 ± 0.263
3.894IleArg: 3.894 ± 0.333
6.055IleSer: 6.055 ± 0.432
4.908IleThr: 4.908 ± 0.423
2.987IleVal: 2.987 ± 0.278
0.667IleTrp: 0.667 ± 0.13
3.014IleTyr: 3.014 ± 0.319
0.0IleXaa: 0.0 ± 0.0
Lys
2.08LysAla: 2.08 ± 0.22
0.613LysCys: 0.613 ± 0.153
1.6LysAsp: 1.6 ± 0.2
1.254LysGlu: 1.254 ± 0.156
1.44LysPhe: 1.44 ± 0.199
1.494LysGly: 1.494 ± 0.185
0.987LysHis: 0.987 ± 0.244
2.0LysIle: 2.0 ± 0.269
1.414LysLys: 1.414 ± 0.263
3.601LysLeu: 3.601 ± 0.449
0.827LysMet: 0.827 ± 0.17
2.08LysAsn: 2.08 ± 0.223
2.027LysPro: 2.027 ± 0.247
1.36LysGln: 1.36 ± 0.19
2.827LysArg: 2.827 ± 0.228
2.454LysSer: 2.454 ± 0.273
3.121LysThr: 3.121 ± 0.26
1.76LysVal: 1.76 ± 0.207
0.453LysTrp: 0.453 ± 0.112
1.334LysTyr: 1.334 ± 0.231
0.0LysXaa: 0.0 ± 0.0
Leu
7.202LeuAla: 7.202 ± 0.409
2.054LeuCys: 2.054 ± 0.271
4.908LeuAsp: 4.908 ± 0.475
5.361LeuGlu: 5.361 ± 0.555
3.974LeuPhe: 3.974 ± 0.377
6.081LeuGly: 6.081 ± 0.444
2.641LeuHis: 2.641 ± 0.256
6.108LeuIle: 6.108 ± 0.4
3.788LeuLys: 3.788 ± 0.432
10.563LeuLeu: 10.563 ± 0.586
2.214LeuMet: 2.214 ± 0.231
4.214LeuAsn: 4.214 ± 0.326
5.095LeuPro: 5.095 ± 0.338
3.227LeuGln: 3.227 ± 0.279
6.455LeuArg: 6.455 ± 0.355
6.908LeuSer: 6.908 ± 0.478
7.202LeuThr: 7.202 ± 0.535
5.841LeuVal: 5.841 ± 0.397
0.854LeuTrp: 0.854 ± 0.15
3.121LeuTyr: 3.121 ± 0.34
0.0LeuXaa: 0.0 ± 0.0
Met
2.294MetAla: 2.294 ± 0.242
0.587MetCys: 0.587 ± 0.117
1.867MetAsp: 1.867 ± 0.186
1.574MetGlu: 1.574 ± 0.215
0.96MetPhe: 0.96 ± 0.182
1.574MetGly: 1.574 ± 0.188
0.4MetHis: 0.4 ± 0.1
1.387MetIle: 1.387 ± 0.221
0.8MetLys: 0.8 ± 0.142
2.321MetLeu: 2.321 ± 0.266
0.774MetMet: 0.774 ± 0.134
0.747MetAsn: 0.747 ± 0.176
0.72MetPro: 0.72 ± 0.163
0.347MetGln: 0.347 ± 0.074
1.76MetArg: 1.76 ± 0.229
1.734MetSer: 1.734 ± 0.242
1.414MetThr: 1.414 ± 0.2
1.52MetVal: 1.52 ± 0.193
0.24MetTrp: 0.24 ± 0.082
0.56MetTyr: 0.56 ± 0.15
0.0MetXaa: 0.0 ± 0.0
Asn
2.294AsnAla: 2.294 ± 0.216
0.693AsnCys: 0.693 ± 0.14
2.054AsnAsp: 2.054 ± 0.247
1.654AsnGlu: 1.654 ± 0.24
1.76AsnPhe: 1.76 ± 0.263
2.721AsnGly: 2.721 ± 0.302
1.414AsnHis: 1.414 ± 0.263
3.494AsnIle: 3.494 ± 0.317
1.254AsnLys: 1.254 ± 0.202
3.814AsnLeu: 3.814 ± 0.425
0.987AsnMet: 0.987 ± 0.167
2.08AsnAsn: 2.08 ± 0.277
2.854AsnPro: 2.854 ± 0.295
1.494AsnGln: 1.494 ± 0.252
2.454AsnArg: 2.454 ± 0.211
2.907AsnSer: 2.907 ± 0.281
3.387AsnThr: 3.387 ± 0.322
2.454AsnVal: 2.454 ± 0.226
0.187AsnTrp: 0.187 ± 0.065
1.627AsnTyr: 1.627 ± 0.255
0.0AsnXaa: 0.0 ± 0.0
Pro
3.147ProAla: 3.147 ± 0.324
1.04ProCys: 1.04 ± 0.149
3.174ProAsp: 3.174 ± 0.288
3.574ProGlu: 3.574 ± 0.308
1.814ProPhe: 1.814 ± 0.198
3.441ProGly: 3.441 ± 0.389
1.334ProHis: 1.334 ± 0.187
4.054ProIle: 4.054 ± 0.359
2.0ProLys: 2.0 ± 0.288
5.041ProLeu: 5.041 ± 0.428
1.52ProMet: 1.52 ± 0.237
2.347ProAsn: 2.347 ± 0.27
5.468ProPro: 5.468 ± 0.604
1.814ProGln: 1.814 ± 0.198
4.294ProArg: 4.294 ± 0.455
4.748ProSer: 4.748 ± 0.43
3.894ProThr: 3.894 ± 0.435
3.494ProVal: 3.494 ± 0.352
0.4ProTrp: 0.4 ± 0.116
1.334ProTyr: 1.334 ± 0.195
0.0ProXaa: 0.0 ± 0.0
Gln
2.161GlnAla: 2.161 ± 0.256
0.347GlnCys: 0.347 ± 0.103
1.68GlnAsp: 1.68 ± 0.176
1.387GlnGlu: 1.387 ± 0.162
1.6GlnPhe: 1.6 ± 0.278
1.467GlnGly: 1.467 ± 0.182
0.8GlnHis: 0.8 ± 0.123
2.107GlnIle: 2.107 ± 0.179
0.934GlnLys: 0.934 ± 0.15
2.747GlnLeu: 2.747 ± 0.272
0.587GlnMet: 0.587 ± 0.107
1.227GlnAsn: 1.227 ± 0.243
2.427GlnPro: 2.427 ± 0.277
1.12GlnGln: 1.12 ± 0.185
2.694GlnArg: 2.694 ± 0.29
2.481GlnSer: 2.481 ± 0.268
2.507GlnThr: 2.507 ± 0.243
1.654GlnVal: 1.654 ± 0.226
0.347GlnTrp: 0.347 ± 0.078
1.014GlnTyr: 1.014 ± 0.2
0.0GlnXaa: 0.0 ± 0.0
Arg
4.694ArgAla: 4.694 ± 0.418
1.12ArgCys: 1.12 ± 0.202
4.268ArgAsp: 4.268 ± 0.345
3.201ArgGlu: 3.201 ± 0.301
2.267ArgPhe: 2.267 ± 0.266
4.428ArgGly: 4.428 ± 0.489
2.321ArgHis: 2.321 ± 0.208
3.361ArgIle: 3.361 ± 0.224
2.0ArgLys: 2.0 ± 0.286
7.468ArgLeu: 7.468 ± 0.476
1.12ArgMet: 1.12 ± 0.188
2.0ArgAsn: 2.0 ± 0.225
3.548ArgPro: 3.548 ± 0.335
2.134ArgGln: 2.134 ± 0.236
6.722ArgArg: 6.722 ± 0.691
5.335ArgSer: 5.335 ± 0.39
3.334ArgThr: 3.334 ± 0.316
4.374ArgVal: 4.374 ± 0.355
0.693ArgTrp: 0.693 ± 0.139
2.427ArgTyr: 2.427 ± 0.28
0.0ArgXaa: 0.0 ± 0.0
Ser
5.148SerAla: 5.148 ± 0.36
1.574SerCys: 1.574 ± 0.225
4.561SerAsp: 4.561 ± 0.372
3.761SerGlu: 3.761 ± 0.358
2.481SerPhe: 2.481 ± 0.244
5.895SerGly: 5.895 ± 0.424
2.0SerHis: 2.0 ± 0.233
5.175SerIle: 5.175 ± 0.313
2.881SerLys: 2.881 ± 0.338
7.575SerLeu: 7.575 ± 0.424
2.0SerMet: 2.0 ± 0.199
3.521SerAsn: 3.521 ± 0.268
4.428SerPro: 4.428 ± 0.503
3.147SerGln: 3.147 ± 0.342
4.668SerArg: 4.668 ± 0.373
8.509SerSer: 8.509 ± 0.749
6.882SerThr: 6.882 ± 0.444
4.428SerVal: 4.428 ± 0.454
0.8SerTrp: 0.8 ± 0.149
1.974SerTyr: 1.974 ± 0.257
0.0SerXaa: 0.0 ± 0.0
Thr
4.881ThrAla: 4.881 ± 0.348
1.307ThrCys: 1.307 ± 0.198
3.761ThrAsp: 3.761 ± 0.306
3.014ThrGlu: 3.014 ± 0.329
2.747ThrPhe: 2.747 ± 0.253
4.108ThrGly: 4.108 ± 0.357
1.84ThrHis: 1.84 ± 0.256
4.401ThrIle: 4.401 ± 0.34
2.427ThrLys: 2.427 ± 0.193
6.988ThrLeu: 6.988 ± 0.378
1.414ThrMet: 1.414 ± 0.166
2.934ThrAsn: 2.934 ± 0.265
5.868ThrPro: 5.868 ± 0.478
2.401ThrGln: 2.401 ± 0.273
4.748ThrArg: 4.748 ± 0.284
6.482ThrSer: 6.482 ± 0.372
6.081ThrThr: 6.081 ± 0.463
4.134ThrVal: 4.134 ± 0.321
0.8ThrTrp: 0.8 ± 0.14
2.374ThrTyr: 2.374 ± 0.242
0.0ThrXaa: 0.0 ± 0.0
Val
4.428ValAla: 4.428 ± 0.288
1.307ValCys: 1.307 ± 0.192
3.734ValAsp: 3.734 ± 0.311
3.334ValGlu: 3.334 ± 0.334
2.507ValPhe: 2.507 ± 0.282
3.121ValGly: 3.121 ± 0.241
1.387ValHis: 1.387 ± 0.145
4.321ValIle: 4.321 ± 0.332
2.187ValLys: 2.187 ± 0.25
5.495ValLeu: 5.495 ± 0.363
1.547ValMet: 1.547 ± 0.192
2.694ValAsn: 2.694 ± 0.363
2.907ValPro: 2.907 ± 0.31
1.627ValGln: 1.627 ± 0.206
3.227ValArg: 3.227 ± 0.308
5.228ValSer: 5.228 ± 0.376
4.348ValThr: 4.348 ± 0.307
3.628ValVal: 3.628 ± 0.335
0.613ValTrp: 0.613 ± 0.118
2.587ValTyr: 2.587 ± 0.291
0.0ValXaa: 0.0 ± 0.0
Trp
0.587TrpAla: 0.587 ± 0.116
0.24TrpCys: 0.24 ± 0.101
0.747TrpAsp: 0.747 ± 0.119
0.373TrpGlu: 0.373 ± 0.113
0.427TrpPhe: 0.427 ± 0.128
0.453TrpGly: 0.453 ± 0.094
0.16TrpHis: 0.16 ± 0.055
0.56TrpIle: 0.56 ± 0.113
0.347TrpLys: 0.347 ± 0.102
0.827TrpLeu: 0.827 ± 0.124
0.267TrpMet: 0.267 ± 0.091
0.4TrpAsn: 0.4 ± 0.103
0.427TrpPro: 0.427 ± 0.132
0.267TrpGln: 0.267 ± 0.082
0.774TrpArg: 0.774 ± 0.145
0.907TrpSer: 0.907 ± 0.145
0.88TrpThr: 0.88 ± 0.138
0.56TrpVal: 0.56 ± 0.114
0.16TrpTrp: 0.16 ± 0.064
0.32TrpTyr: 0.32 ± 0.094
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.894TyrAla: 1.894 ± 0.249
0.747TyrCys: 0.747 ± 0.148
1.894TyrAsp: 1.894 ± 0.224
1.414TyrGlu: 1.414 ± 0.259
1.307TyrPhe: 1.307 ± 0.18
2.08TyrGly: 2.08 ± 0.201
0.96TyrHis: 0.96 ± 0.172
3.014TyrIle: 3.014 ± 0.408
1.334TyrLys: 1.334 ± 0.222
3.094TyrLeu: 3.094 ± 0.329
0.907TyrMet: 0.907 ± 0.146
1.76TyrAsn: 1.76 ± 0.197
1.68TyrPro: 1.68 ± 0.248
0.907TyrGln: 0.907 ± 0.178
2.107TyrArg: 2.107 ± 0.216
2.134TyrSer: 2.134 ± 0.224
3.014TyrThr: 3.014 ± 0.246
2.054TyrVal: 2.054 ± 0.228
0.48TyrTrp: 0.48 ± 0.128
1.174TyrTyr: 1.174 ± 0.165
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 73 proteins (37492 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski