Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis agent) (Calyptromyces circinelloides)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina; Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor; Mucor circinelloides

Average proteome isoelectric point is 6.5

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 12143 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|S2K4Q1|S2K4Q1_MUCC1 TLC domain-containing protein OS=Mucor circinelloides f. circinelloides (strain 1006PhL) OX=1220926 GN=HMPREF1544_02848 PE=3 SV=1
MM1 pKa = 7.5FKK3 pKa = 9.97PSKK6 pKa = 10.39SIAIFLIAFLVTMIQVSAAPVEE28 pKa = 4.56RR29 pKa = 11.84PANSAVEE36 pKa = 3.87ASGAEE41 pKa = 4.06EE42 pKa = 4.05ASFDD46 pKa = 4.63SLYY49 pKa = 11.56DD50 pKa = 3.44MYY52 pKa = 11.37KK53 pKa = 10.26PLYY56 pKa = 8.63DD57 pKa = 3.24QYY59 pKa = 9.99YY60 pKa = 7.5THH62 pKa = 7.46LASKK66 pKa = 10.64SLIARR71 pKa = 11.84SNEE74 pKa = 3.95DD75 pKa = 3.67EE76 pKa = 5.12DD77 pKa = 6.05HH78 pKa = 7.68DD79 pKa = 4.33EE80 pKa = 4.69CDD82 pKa = 5.42DD83 pKa = 6.09DD84 pKa = 5.96GSCDD88 pKa = 5.53DD89 pKa = 5.91RR90 pKa = 11.84DD91 pKa = 4.18DD92 pKa = 4.33DD93 pKa = 6.19HH94 pKa = 7.61NGCDD98 pKa = 5.84DD99 pKa = 6.47DD100 pKa = 7.26DD101 pKa = 5.47DD102 pKa = 4.67SCNDD106 pKa = 3.32RR107 pKa = 11.84DD108 pKa = 4.2NNHH111 pKa = 7.09DD112 pKa = 3.81EE113 pKa = 5.02CDD115 pKa = 4.29DD116 pKa = 5.87DD117 pKa = 6.08SDD119 pKa = 4.24SCNGRR124 pKa = 11.84DD125 pKa = 4.32DD126 pKa = 4.28EE127 pKa = 4.65NNEE130 pKa = 4.16HH131 pKa = 6.93EE132 pKa = 4.6STSASSATVIYY143 pKa = 9.95PPFPPFPPPPTFPPFPPPPVFPPFPPFSS171 pKa = 3.59

Molecular weight: 18.94 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|S2J1L7|S2J1L7_MUCC1 Uncharacterized protein OS=Mucor circinelloides f. circinelloides (strain 1006PhL) OX=1220926 GN=HMPREF1544_09290 PE=4 SV=1
MM1 pKa = 7.57GNTHH5 pKa = 5.23STATRR10 pKa = 11.84RR11 pKa = 11.84QAAPRR16 pKa = 11.84AVKK19 pKa = 8.98TRR21 pKa = 11.84KK22 pKa = 8.79SPRR25 pKa = 11.84RR26 pKa = 11.84FGLPSQRR33 pKa = 11.84RR34 pKa = 11.84AAAAPVTVKK43 pKa = 10.12PRR45 pKa = 11.84RR46 pKa = 11.84KK47 pKa = 9.59FGFGSSRR54 pKa = 11.84KK55 pKa = 8.66HH56 pKa = 4.25RR57 pKa = 11.84HH58 pKa = 4.73GAAAAPVAATTVPSNSMTLRR78 pKa = 11.84KK79 pKa = 9.52LKK81 pKa = 10.81AKK83 pKa = 10.19ISPGPKK89 pKa = 9.35VATTSKK95 pKa = 10.38RR96 pKa = 11.84SRR98 pKa = 11.84KK99 pKa = 8.71HH100 pKa = 5.66AKK102 pKa = 9.23KK103 pKa = 10.58DD104 pKa = 3.61PVSGLVDD111 pKa = 3.66KK112 pKa = 10.21LAPAAGVSAAPRR124 pKa = 11.84HH125 pKa = 5.83RR126 pKa = 11.84SRR128 pKa = 11.84GFGFGRR134 pKa = 11.84RR135 pKa = 11.84RR136 pKa = 11.84PAQPPVTTKK145 pKa = 10.47RR146 pKa = 11.84GMFSRR151 pKa = 11.84FQRR154 pKa = 11.84ARR156 pKa = 11.84AYY158 pKa = 10.3

Molecular weight: 17.11 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

12143

0

12143

5338243

49

6146

439.6

49.45

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.111 ± 0.021

1.36 ± 0.009

5.866 ± 0.016

6.182 ± 0.024

3.935 ± 0.013

5.013 ± 0.022

2.585 ± 0.011

5.856 ± 0.016

6.243 ± 0.025

8.89 ± 0.024

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.479 ± 0.008

4.948 ± 0.013

4.881 ± 0.018

4.922 ± 0.024

4.767 ± 0.016

8.373 ± 0.03

6.216 ± 0.021

5.92 ± 0.016

1.119 ± 0.007

3.336 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski