Amino acid dipepetide frequency for Torque teno virus (isolate Human/Japan/SANBAN/1999) (TTV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.897AlaAla: 6.897 ± 3.984
1.97AlaCys: 1.97 ± 2.738
4.926AlaAsp: 4.926 ± 1.246
2.956AlaGlu: 2.956 ± 1.492
0.985AlaPhe: 0.985 ± 0.497
6.897AlaGly: 6.897 ± 5.851
4.926AlaHis: 4.926 ± 4.979
4.926AlaIle: 4.926 ± 3.113
2.956AlaLys: 2.956 ± 1.492
2.956AlaLeu: 2.956 ± 0.374
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
2.956AlaPro: 2.956 ± 2.241
0.985AlaGln: 0.985 ± 1.369
4.926AlaArg: 4.926 ± 1.246
3.941AlaSer: 3.941 ± 0.123
2.956AlaThr: 2.956 ± 1.492
0.985AlaVal: 0.985 ± 0.497
0.985AlaTrp: 0.985 ± 0.497
2.956AlaTyr: 2.956 ± 1.492
0.0AlaXaa: 0.0 ± 0.0
Cys
0.985CysAla: 0.985 ± 0.497
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.985CysPhe: 0.985 ± 1.369
2.956CysGly: 2.956 ± 2.241
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.956CysLys: 2.956 ± 1.492
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.97CysPro: 1.97 ± 0.995
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.941CysSer: 3.941 ± 3.61
1.97CysThr: 1.97 ± 0.872
0.985CysVal: 0.985 ± 0.497
0.0CysTrp: 0.0 ± 0.0
0.985CysTyr: 0.985 ± 0.497
0.0CysXaa: 0.0 ± 0.0
Asp
6.897AspAla: 6.897 ± 5.851
0.0AspCys: 0.0 ± 0.0
2.956AspAsp: 2.956 ± 2.241
2.956AspGlu: 2.956 ± 0.374
0.985AspPhe: 0.985 ± 0.497
4.926AspGly: 4.926 ± 1.246
0.0AspHis: 0.0 ± 0.0
2.956AspIle: 2.956 ± 1.492
2.956AspLys: 2.956 ± 1.492
5.911AspLeu: 5.911 ± 0.749
0.0AspMet: 0.0 ± 0.0
0.985AspAsn: 0.985 ± 0.497
1.97AspPro: 1.97 ± 0.872
1.97AspGln: 1.97 ± 0.995
2.956AspArg: 2.956 ± 1.492
2.956AspSer: 2.956 ± 0.374
2.956AspThr: 2.956 ± 0.374
0.985AspVal: 0.985 ± 0.497
1.97AspTrp: 1.97 ± 0.995
2.956AspTyr: 2.956 ± 1.492
0.0AspXaa: 0.0 ± 0.0
Glu
1.97GluAla: 1.97 ± 0.872
0.0GluCys: 0.0 ± 0.0
2.956GluAsp: 2.956 ± 0.374
6.897GluGlu: 6.897 ± 0.251
1.97GluPhe: 1.97 ± 0.995
4.926GluGly: 4.926 ± 1.246
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
3.941GluLys: 3.941 ± 0.123
3.941GluLeu: 3.941 ± 1.743
1.97GluMet: 1.97 ± 0.995
0.985GluAsn: 0.985 ± 0.497
2.956GluPro: 2.956 ± 1.492
3.941GluGln: 3.941 ± 1.99
1.97GluArg: 1.97 ± 0.872
7.882GluSer: 7.882 ± 3.487
2.956GluThr: 2.956 ± 1.492
0.0GluVal: 0.0 ± 0.0
0.0GluTrp: 0.0 ± 0.0
1.97GluTyr: 1.97 ± 0.872
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.985PheCys: 0.985 ± 0.497
1.97PheAsp: 1.97 ± 0.995
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
2.956PheGly: 2.956 ± 1.492
0.985PheHis: 0.985 ± 0.497
2.956PheIle: 2.956 ± 0.374
1.97PheLys: 1.97 ± 0.995
4.926PheLeu: 4.926 ± 0.621
0.0PheMet: 0.0 ± 0.0
0.985PheAsn: 0.985 ± 0.497
2.956PhePro: 2.956 ± 1.492
3.941PheGln: 3.941 ± 1.99
2.956PheArg: 2.956 ± 0.374
3.941PheSer: 3.941 ± 1.99
2.956PheThr: 2.956 ± 0.374
1.97PheVal: 1.97 ± 0.995
0.0PheTrp: 0.0 ± 0.0
5.911PheTyr: 5.911 ± 2.985
0.0PheXaa: 0.0 ± 0.0
Gly
4.926GlyAla: 4.926 ± 3.113
2.956GlyCys: 2.956 ± 2.241
3.941GlyAsp: 3.941 ± 3.61
2.956GlyGlu: 2.956 ± 2.241
1.97GlyPhe: 1.97 ± 0.872
7.882GlyGly: 7.882 ± 5.354
0.985GlyHis: 0.985 ± 0.497
1.97GlyIle: 1.97 ± 0.872
1.97GlyLys: 1.97 ± 0.995
2.956GlyLeu: 2.956 ± 1.492
0.985GlyMet: 0.985 ± 0.497
4.926GlyAsn: 4.926 ± 0.621
7.882GlyPro: 7.882 ± 3.487
1.97GlyGln: 1.97 ± 0.995
7.882GlyArg: 7.882 ± 0.246
5.911GlySer: 5.911 ± 0.749
0.985GlyThr: 0.985 ± 1.369
0.985GlyVal: 0.985 ± 0.497
1.97GlyTrp: 1.97 ± 0.995
4.926GlyTyr: 4.926 ± 2.487
0.0GlyXaa: 0.0 ± 0.0
His
0.985HisAla: 0.985 ± 1.369
0.0HisCys: 0.0 ± 0.0
0.985HisAsp: 0.985 ± 1.369
0.985HisGlu: 0.985 ± 0.497
0.985HisPhe: 0.985 ± 0.497
0.985HisGly: 0.985 ± 1.369
0.0HisHis: 0.0 ± 0.0
3.941HisIle: 3.941 ± 1.743
1.97HisLys: 1.97 ± 0.995
1.97HisLeu: 1.97 ± 0.872
0.0HisMet: 0.0 ± 0.0
0.985HisAsn: 0.985 ± 1.369
2.956HisPro: 2.956 ± 1.492
0.985HisGln: 0.985 ± 0.497
0.985HisArg: 0.985 ± 0.497
1.97HisSer: 1.97 ± 0.995
0.985HisThr: 0.985 ± 0.497
0.985HisVal: 0.985 ± 0.497
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.985HisXaa: 0.985 ± 0.497
Ile
0.985IleAla: 0.985 ± 1.369
1.97IleCys: 1.97 ± 0.995
1.97IleAsp: 1.97 ± 0.872
4.926IleGlu: 4.926 ± 1.246
2.956IlePhe: 2.956 ± 1.492
1.97IleGly: 1.97 ± 0.995
0.0IleHis: 0.0 ± 0.0
0.985IleIle: 0.985 ± 0.497
2.956IleLys: 2.956 ± 1.492
2.956IleLeu: 2.956 ± 2.241
0.0IleMet: 0.0 ± 0.0
2.956IleAsn: 2.956 ± 0.374
2.956IlePro: 2.956 ± 1.492
1.97IleGln: 1.97 ± 0.872
0.0IleArg: 0.0 ± 0.0
1.97IleSer: 1.97 ± 0.995
1.97IleThr: 1.97 ± 0.995
3.941IleVal: 3.941 ± 1.99
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.926LysAla: 4.926 ± 1.246
0.985LysCys: 0.985 ± 1.369
1.97LysAsp: 1.97 ± 0.872
0.985LysGlu: 0.985 ± 0.497
2.956LysPhe: 2.956 ± 1.492
6.897LysGly: 6.897 ± 1.616
0.985LysHis: 0.985 ± 0.497
2.956LysIle: 2.956 ± 1.492
5.911LysLys: 5.911 ± 0.749
1.97LysLeu: 1.97 ± 0.995
0.0LysMet: 0.0 ± 0.0
3.941LysAsn: 3.941 ± 1.99
2.956LysPro: 2.956 ± 0.374
1.97LysGln: 1.97 ± 0.995
5.911LysArg: 5.911 ± 0.749
1.97LysSer: 1.97 ± 0.872
3.941LysThr: 3.941 ± 0.123
1.97LysVal: 1.97 ± 0.995
4.926LysTrp: 4.926 ± 1.246
1.97LysTyr: 1.97 ± 0.995
0.0LysXaa: 0.0 ± 0.0
Leu
5.911LeuAla: 5.911 ± 2.615
0.985LeuCys: 0.985 ± 0.497
3.941LeuAsp: 3.941 ± 0.123
2.956LeuGlu: 2.956 ± 2.241
2.956LeuPhe: 2.956 ± 1.492
2.956LeuGly: 2.956 ± 0.374
5.911LeuHis: 5.911 ± 1.118
4.926LeuIle: 4.926 ± 2.487
3.941LeuLys: 3.941 ± 1.99
4.926LeuLeu: 4.926 ± 1.246
0.985LeuMet: 0.985 ± 0.497
0.985LeuAsn: 0.985 ± 0.497
1.97LeuPro: 1.97 ± 0.872
2.956LeuGln: 2.956 ± 2.241
3.941LeuArg: 3.941 ± 1.99
4.926LeuSer: 4.926 ± 1.246
2.956LeuThr: 2.956 ± 0.374
1.97LeuVal: 1.97 ± 0.995
0.985LeuTrp: 0.985 ± 0.497
0.985LeuTyr: 0.985 ± 0.497
0.0LeuXaa: 0.0 ± 0.0
Met
1.97MetAla: 1.97 ± 0.995
0.0MetCys: 0.0 ± 0.0
0.985MetAsp: 0.985 ± 0.497
0.0MetGlu: 0.0 ± 0.0
2.956MetPhe: 2.956 ± 1.492
1.97MetGly: 1.97 ± 0.995
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.985MetLys: 0.985 ± 1.369
1.97MetLeu: 1.97 ± 0.995
1.97MetMet: 1.97 ± 0.995
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.97MetSer: 1.97 ± 0.872
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.985MetTyr: 0.985 ± 0.497
0.0MetXaa: 0.0 ± 0.0
Asn
1.97AsnAla: 1.97 ± 0.872
0.0AsnCys: 0.0 ± 0.0
1.97AsnAsp: 1.97 ± 0.995
0.0AsnGlu: 0.0 ± 0.0
1.97AsnPhe: 1.97 ± 0.872
0.0AsnGly: 0.0 ± 0.0
0.985AsnHis: 0.985 ± 0.497
0.985AsnIle: 0.985 ± 0.497
4.926AsnLys: 4.926 ± 0.621
3.941AsnLeu: 3.941 ± 1.743
0.985AsnMet: 0.985 ± 0.497
0.0AsnAsn: 0.0 ± 0.0
5.911AsnPro: 5.911 ± 2.985
0.985AsnGln: 0.985 ± 1.369
0.985AsnArg: 0.985 ± 1.369
3.941AsnSer: 3.941 ± 1.743
2.956AsnThr: 2.956 ± 1.492
1.97AsnVal: 1.97 ± 0.995
1.97AsnTrp: 1.97 ± 0.872
3.941AsnTyr: 3.941 ± 1.99
0.0AsnXaa: 0.0 ± 0.0
Pro
5.911ProAla: 5.911 ± 2.615
2.956ProCys: 2.956 ± 1.492
1.97ProAsp: 1.97 ± 0.995
3.941ProGlu: 3.941 ± 0.123
4.926ProPhe: 4.926 ± 2.487
4.926ProGly: 4.926 ± 4.979
0.0ProHis: 0.0 ± 0.0
1.97ProIle: 1.97 ± 0.872
1.97ProLys: 1.97 ± 0.872
5.911ProLeu: 5.911 ± 0.749
2.956ProMet: 2.956 ± 1.492
1.97ProAsn: 1.97 ± 0.995
12.808ProPro: 12.808 ± 10.333
4.926ProGln: 4.926 ± 1.246
4.926ProArg: 4.926 ± 2.487
0.985ProSer: 0.985 ± 0.497
3.941ProThr: 3.941 ± 0.123
1.97ProVal: 1.97 ± 0.872
0.985ProTrp: 0.985 ± 1.369
2.956ProTyr: 2.956 ± 1.492
0.985ProXaa: 0.985 ± 0.497
Gln
3.941GlnAla: 3.941 ± 1.99
0.985GlnCys: 0.985 ± 1.369
0.985GlnAsp: 0.985 ± 0.497
1.97GlnGlu: 1.97 ± 0.995
0.985GlnPhe: 0.985 ± 0.497
0.985GlnGly: 0.985 ± 0.497
0.985GlnHis: 0.985 ± 0.497
0.0GlnIle: 0.0 ± 0.0
2.956GlnLys: 2.956 ± 2.241
3.941GlnLeu: 3.941 ± 1.99
0.985GlnMet: 0.985 ± 0.497
0.0GlnAsn: 0.0 ± 0.0
3.941GlnPro: 3.941 ± 0.123
5.911GlnGln: 5.911 ± 2.615
5.911GlnArg: 5.911 ± 2.615
0.0GlnSer: 0.0 ± 0.0
4.926GlnThr: 4.926 ± 2.487
3.941GlnVal: 3.941 ± 0.123
1.97GlnTrp: 1.97 ± 0.995
2.956GlnTyr: 2.956 ± 0.374
0.0GlnXaa: 0.0 ± 0.0
Arg
4.926ArgAla: 4.926 ± 3.113
0.985ArgCys: 0.985 ± 0.497
0.0ArgAsp: 0.0 ± 0.0
4.926ArgGlu: 4.926 ± 1.246
0.985ArgPhe: 0.985 ± 0.497
6.897ArgGly: 6.897 ± 3.482
1.97ArgHis: 1.97 ± 0.995
0.985ArgIle: 0.985 ± 0.497
5.911ArgLys: 5.911 ± 2.615
2.956ArgLeu: 2.956 ± 1.492
0.985ArgMet: 0.985 ± 0.422
6.897ArgAsn: 6.897 ± 3.984
6.897ArgPro: 6.897 ± 1.616
3.941ArgGln: 3.941 ± 1.743
34.483ArgArg: 34.483 ± 6.212
1.97ArgSer: 1.97 ± 0.872
5.911ArgThr: 5.911 ± 0.749
0.985ArgVal: 0.985 ± 1.369
5.911ArgTrp: 5.911 ± 2.985
3.941ArgTyr: 3.941 ± 0.123
0.0ArgXaa: 0.0 ± 0.0
Ser
2.956SerAla: 2.956 ± 1.492
2.956SerCys: 2.956 ± 0.374
4.926SerAsp: 4.926 ± 0.621
6.897SerGlu: 6.897 ± 0.251
4.926SerPhe: 4.926 ± 0.621
0.985SerGly: 0.985 ± 1.369
1.97SerHis: 1.97 ± 0.995
0.0SerIle: 0.0 ± 0.0
1.97SerLys: 1.97 ± 2.738
1.97SerLeu: 1.97 ± 0.995
0.0SerMet: 0.0 ± 0.0
4.926SerAsn: 4.926 ± 3.113
4.926SerPro: 4.926 ± 3.113
2.956SerGln: 2.956 ± 1.492
2.956SerArg: 2.956 ± 2.241
11.823SerSer: 11.823 ± 14.564
5.911SerThr: 5.911 ± 2.615
0.985SerVal: 0.985 ± 0.497
0.985SerTrp: 0.985 ± 1.369
4.926SerTyr: 4.926 ± 2.487
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.0ThrCys: 0.0 ± 0.0
6.897ThrAsp: 6.897 ± 1.616
2.956ThrGlu: 2.956 ± 1.492
0.985ThrPhe: 0.985 ± 0.497
4.926ThrGly: 4.926 ± 1.246
0.0ThrHis: 0.0 ± 0.0
2.956ThrIle: 2.956 ± 1.492
3.941ThrLys: 3.941 ± 1.99
1.97ThrLeu: 1.97 ± 0.872
0.985ThrMet: 0.985 ± 2.087
2.956ThrAsn: 2.956 ± 1.492
5.911ThrPro: 5.911 ± 2.615
3.941ThrGln: 3.941 ± 1.99
5.911ThrArg: 5.911 ± 2.615
1.97ThrSer: 1.97 ± 0.995
3.941ThrThr: 3.941 ± 1.99
3.941ThrVal: 3.941 ± 1.99
0.985ThrTrp: 0.985 ± 0.497
2.956ThrTyr: 2.956 ± 1.492
0.985ThrXaa: 0.985 ± 0.497
Val
1.97ValAla: 1.97 ± 0.995
0.0ValCys: 0.0 ± 0.0
1.97ValAsp: 1.97 ± 0.995
0.0ValGlu: 0.0 ± 0.0
3.941ValPhe: 3.941 ± 1.99
1.97ValGly: 1.97 ± 0.995
0.985ValHis: 0.985 ± 1.369
1.97ValIle: 1.97 ± 0.995
1.97ValLys: 1.97 ± 0.995
3.941ValLeu: 3.941 ± 1.99
0.985ValMet: 0.985 ± 0.497
1.97ValAsn: 1.97 ± 0.995
0.985ValPro: 0.985 ± 0.497
0.985ValGln: 0.985 ± 0.497
3.941ValArg: 3.941 ± 0.123
2.956ValSer: 2.956 ± 0.374
1.97ValThr: 1.97 ± 0.995
0.0ValVal: 0.0 ± 0.0
0.985ValTrp: 0.985 ± 0.497
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.985TrpAla: 0.985 ± 0.497
0.0TrpCys: 0.0 ± 0.0
0.985TrpAsp: 0.985 ± 1.369
0.985TrpGlu: 0.985 ± 0.497
0.985TrpPhe: 0.985 ± 0.497
2.956TrpGly: 2.956 ± 1.492
0.985TrpHis: 0.985 ± 1.369
1.97TrpIle: 1.97 ± 0.995
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.985TrpPro: 0.985 ± 0.497
1.97TrpGln: 1.97 ± 0.995
7.882TrpArg: 7.882 ± 0.246
0.985TrpSer: 0.985 ± 0.497
0.985TrpThr: 0.985 ± 0.497
0.985TrpVal: 0.985 ± 0.497
0.985TrpTrp: 0.985 ± 0.497
2.956TrpTyr: 2.956 ± 0.374
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.97TyrAla: 1.97 ± 0.995
0.0TyrCys: 0.0 ± 0.0
2.956TyrAsp: 2.956 ± 1.492
3.941TyrGlu: 3.941 ± 0.123
2.956TyrPhe: 2.956 ± 1.492
1.97TyrGly: 1.97 ± 0.872
1.97TyrHis: 1.97 ± 0.995
0.0TyrIle: 0.0 ± 0.0
3.941TyrLys: 3.941 ± 0.123
1.97TyrLeu: 1.97 ± 0.995
0.985TyrMet: 0.985 ± 0.497
4.926TyrAsn: 4.926 ± 2.487
0.0TyrPro: 0.0 ± 0.0
1.97TyrGln: 1.97 ± 0.995
3.941TyrArg: 3.941 ± 1.99
3.941TyrSer: 3.941 ± 0.123
4.926TyrThr: 4.926 ± 2.487
3.941TyrVal: 3.941 ± 1.99
1.97TyrTrp: 1.97 ± 0.995
0.985TyrTyr: 0.985 ± 0.497
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.985XaaAsp: 0.985 ± 0.497
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.985XaaIle: 0.985 ± 0.497
0.0XaaLys: 0.0 ± 0.0
0.985XaaLeu: 0.985 ± 0.497
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1016 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski