Amino acid dipepetide frequency for Phasianus colchicus (Common pheasant)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.283AlaAla: 7.283 ± 0.039	1.366AlaCys: 1.366 ± 0.012	3.093AlaAsp: 3.093 ± 0.014	5.07AlaGlu: 5.07 ± 0.026	2.524AlaPhe: 2.524 ± 0.015	4.566AlaGly: 4.566 ± 0.023	1.422AlaHis: 1.422 ± 0.009	2.957AlaIle: 2.957 ± 0.016	3.567AlaLys: 3.567 ± 0.021	6.878AlaLeu: 6.878 ± 0.033	1.588AlaMet: 1.588 ± 0.011	2.181AlaAsn: 2.181 ± 0.012	3.503AlaPro: 3.503 ± 0.023	2.933AlaGln: 2.933 ± 0.017	3.358AlaArg: 3.358 ± 0.017	5.371AlaSer: 5.371 ± 0.026	3.326AlaThr: 3.326 ± 0.016	5.076AlaVal: 5.076 ± 0.022	0.754AlaTrp: 0.754 ± 0.007	1.55AlaTyr: 1.55 ± 0.011	0.0AlaXaa: 0.0 ± 0.0
Cys	1.288CysAla: 1.288 ± 0.012	0.694CysCys: 0.694 ± 0.009	1.09CysAsp: 1.09 ± 0.014	1.364CysGlu: 1.364 ± 0.018	0.917CysPhe: 0.917 ± 0.009	1.527CysGly: 1.527 ± 0.018	0.673CysHis: 0.673 ± 0.008	1.155CysIle: 1.155 ± 0.015	1.272CysLys: 1.272 ± 0.012	2.19CysLeu: 2.19 ± 0.014	0.464CysMet: 0.464 ± 0.006	0.894CysAsn: 0.894 ± 0.011	1.378CysPro: 1.378 ± 0.018	1.068CysGln: 1.068 ± 0.012	1.304CysArg: 1.304 ± 0.012	2.162CysSer: 2.162 ± 0.016	1.212CysThr: 1.212 ± 0.012	1.414CysVal: 1.414 ± 0.014	0.305CysTrp: 0.305 ± 0.005	0.646CysTyr: 0.646 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	2.988AspAla: 2.988 ± 0.016	1.126AspCys: 1.126 ± 0.012	2.769AspAsp: 2.769 ± 0.019	3.707AspGlu: 3.707 ± 0.018	2.174AspPhe: 2.174 ± 0.014	3.481AspGly: 3.481 ± 0.022	1.099AspHis: 1.099 ± 0.009	2.888AspIle: 2.888 ± 0.018	2.688AspLys: 2.688 ± 0.015	4.896AspLeu: 4.896 ± 0.023	1.135AspMet: 1.135 ± 0.008	1.913AspAsn: 1.913 ± 0.014	2.697AspPro: 2.697 ± 0.015	1.774AspGln: 1.774 ± 0.011	2.344AspArg: 2.344 ± 0.014	4.155AspSer: 4.155 ± 0.018	2.502AspThr: 2.502 ± 0.013	3.211AspVal: 3.211 ± 0.016	0.63AspTrp: 0.63 ± 0.007	1.56AspTyr: 1.56 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	4.807GluAla: 4.807 ± 0.029	1.389GluCys: 1.389 ± 0.021	4.445GluAsp: 4.445 ± 0.022	7.915GluGlu: 7.915 ± 0.048	2.1GluPhe: 2.1 ± 0.013	4.025GluGly: 4.025 ± 0.018	1.591GluHis: 1.591 ± 0.013	3.433GluIle: 3.433 ± 0.016	5.589GluLys: 5.589 ± 0.038	6.599GluLeu: 6.599 ± 0.039	1.833GluMet: 1.833 ± 0.012	3.34GluAsn: 3.34 ± 0.019	2.833GluPro: 2.833 ± 0.018	3.329GluGln: 3.329 ± 0.021	4.091GluArg: 4.091 ± 0.022	4.521GluSer: 4.521 ± 0.022	3.473GluThr: 3.473 ± 0.018	4.217GluVal: 4.217 ± 0.019	0.741GluTrp: 0.741 ± 0.007	1.749GluTyr: 1.749 ± 0.011	0.001GluXaa: 0.001 ± 0.0
Phe	2.101PheAla: 2.101 ± 0.013	0.972PheCys: 0.972 ± 0.01	1.761PheAsp: 1.761 ± 0.011	2.072PheGlu: 2.072 ± 0.011	1.725PhePhe: 1.725 ± 0.014	2.184PheGly: 2.184 ± 0.016	1.054PheHis: 1.054 ± 0.009	1.973PheIle: 1.973 ± 0.014	1.834PheLys: 1.834 ± 0.013	4.008PheLeu: 4.008 ± 0.02	0.785PheMet: 0.785 ± 0.007	1.426PheAsn: 1.426 ± 0.011	1.941PhePro: 1.941 ± 0.013	1.801PheGln: 1.801 ± 0.012	1.899PheArg: 1.899 ± 0.013	3.382PheSer: 3.382 ± 0.017	2.076PheThr: 2.076 ± 0.014	2.283PheVal: 2.283 ± 0.014	0.503PheTrp: 0.503 ± 0.006	1.224PheTyr: 1.224 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	4.197GlyAla: 4.197 ± 0.028	1.337GlyCys: 1.337 ± 0.012	3.062GlyAsp: 3.062 ± 0.019	3.904GlyGlu: 3.904 ± 0.022	2.383GlyPhe: 2.383 ± 0.016	4.854GlyGly: 4.854 ± 0.041	1.554GlyHis: 1.554 ± 0.012	2.93GlyIle: 2.93 ± 0.016	3.831GlyLys: 3.831 ± 0.017	5.206GlyLeu: 5.206 ± 0.023	1.392GlyMet: 1.392 ± 0.01	2.52GlyAsn: 2.52 ± 0.014	3.107GlyPro: 3.107 ± 0.035	2.585GlyGln: 2.585 ± 0.015	3.711GlyArg: 3.711 ± 0.022	5.596GlySer: 5.596 ± 0.027	3.606GlyThr: 3.606 ± 0.02	3.5GlyVal: 3.5 ± 0.023	0.854GlyTrp: 0.854 ± 0.009	1.804GlyTyr: 1.804 ± 0.015	0.002GlyXaa: 0.002 ± 0.0
His	1.375HisAla: 1.375 ± 0.01	0.753HisCys: 0.753 ± 0.008	0.933HisAsp: 0.933 ± 0.009	1.364HisGlu: 1.364 ± 0.009	1.056HisPhe: 1.056 ± 0.007	1.568HisGly: 1.568 ± 0.012	0.87HisHis: 0.87 ± 0.011	1.313HisIle: 1.313 ± 0.009	1.296HisLys: 1.296 ± 0.011	2.735HisLeu: 2.735 ± 0.015	0.564HisMet: 0.564 ± 0.007	0.936HisAsn: 0.936 ± 0.008	1.608HisPro: 1.608 ± 0.014	1.187HisGln: 1.187 ± 0.009	1.493HisArg: 1.493 ± 0.011	2.271HisSer: 2.271 ± 0.013	1.298HisThr: 1.298 ± 0.01	1.483HisVal: 1.483 ± 0.01	0.34HisTrp: 0.34 ± 0.005	0.851HisTyr: 0.851 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.909IleAla: 2.909 ± 0.015	1.177IleCys: 1.177 ± 0.011	2.296IleAsp: 2.296 ± 0.015	2.845IleGlu: 2.845 ± 0.016	2.048IlePhe: 2.048 ± 0.014	2.406IleGly: 2.406 ± 0.017	1.317IleHis: 1.317 ± 0.011	2.601IleIle: 2.601 ± 0.016	2.868IleLys: 2.868 ± 0.015	4.699IleLeu: 4.699 ± 0.022	1.046IleMet: 1.046 ± 0.007	2.143IleAsn: 2.143 ± 0.015	2.72IlePro: 2.72 ± 0.014	2.438IleGln: 2.438 ± 0.015	2.451IleArg: 2.451 ± 0.013	4.052IleSer: 4.052 ± 0.019	2.8IleThr: 2.8 ± 0.016	2.718IleVal: 2.718 ± 0.016	0.535IleTrp: 0.535 ± 0.005	1.512IleTyr: 1.512 ± 0.011	0.0IleXaa: 0.0 ± 0.0
Lys	4.006LysAla: 4.006 ± 0.021	1.198LysCys: 1.198 ± 0.01	3.346LysAsp: 3.346 ± 0.018	5.383LysGlu: 5.383 ± 0.035	1.785LysPhe: 1.785 ± 0.011	3.257LysGly: 3.257 ± 0.017	1.506LysHis: 1.506 ± 0.013	2.994LysIle: 2.994 ± 0.016	4.937LysLys: 4.937 ± 0.03	5.505LysLeu: 5.505 ± 0.029	1.525LysMet: 1.525 ± 0.011	2.659LysAsn: 2.659 ± 0.015	2.887LysPro: 2.887 ± 0.018	2.908LysGln: 2.908 ± 0.019	3.337LysArg: 3.337 ± 0.018	4.145LysSer: 4.145 ± 0.02	3.198LysThr: 3.198 ± 0.016	3.573LysVal: 3.573 ± 0.016	0.649LysTrp: 0.649 ± 0.006	1.719LysTyr: 1.719 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	6.22LeuAla: 6.22 ± 0.022	2.309LeuCys: 2.309 ± 0.017	4.723LeuAsp: 4.723 ± 0.018	7.095LeuGlu: 7.095 ± 0.046	3.47LeuPhe: 3.47 ± 0.022	5.235LeuGly: 5.235 ± 0.025	2.755LeuHis: 2.755 ± 0.018	4.082LeuIle: 4.082 ± 0.022	6.099LeuLys: 6.099 ± 0.031	10.466LeuLeu: 10.466 ± 0.046	2.029LeuMet: 2.029 ± 0.013	3.777LeuAsn: 3.777 ± 0.018	5.577LeuPro: 5.577 ± 0.02	5.788LeuGln: 5.788 ± 0.037	5.563LeuArg: 5.563 ± 0.023	7.806LeuSer: 7.806 ± 0.024	4.887LeuThr: 4.887 ± 0.019	5.203LeuVal: 5.203 ± 0.022	1.123LeuTrp: 1.123 ± 0.009	2.634LeuTyr: 2.634 ± 0.015	0.001LeuXaa: 0.001 ± 0.0
Met	1.815MetAla: 1.815 ± 0.014	0.433MetCys: 0.433 ± 0.006	1.305MetAsp: 1.305 ± 0.009	1.97MetGlu: 1.97 ± 0.012	0.785MetPhe: 0.785 ± 0.007	1.338MetGly: 1.338 ± 0.015	0.513MetHis: 0.513 ± 0.005	0.921MetIle: 0.921 ± 0.008	1.565MetLys: 1.565 ± 0.01	2.058MetLeu: 2.058 ± 0.012	0.602MetMet: 0.602 ± 0.007	0.982MetAsn: 0.982 ± 0.009	1.061MetPro: 1.061 ± 0.009	1.055MetGln: 1.055 ± 0.009	1.077MetArg: 1.077 ± 0.009	1.599MetSer: 1.599 ± 0.009	1.098MetThr: 1.098 ± 0.009	1.393MetVal: 1.393 ± 0.01	0.255MetTrp: 0.255 ± 0.004	0.607MetTyr: 0.607 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.336AsnAla: 2.336 ± 0.014	0.972AsnCys: 0.972 ± 0.011	1.699AsnAsp: 1.699 ± 0.011	2.532AsnGlu: 2.532 ± 0.017	1.546AsnPhe: 1.546 ± 0.012	2.756AsnGly: 2.756 ± 0.022	0.958AsnHis: 0.958 ± 0.007	2.367AsnIle: 2.367 ± 0.013	2.431AsnLys: 2.431 ± 0.014	3.899AsnLeu: 3.899 ± 0.018	0.985AsnMet: 0.985 ± 0.008	1.741AsnAsn: 1.741 ± 0.013	2.19AsnPro: 2.19 ± 0.012	1.684AsnGln: 1.684 ± 0.012	1.926AsnArg: 1.926 ± 0.011	3.395AsnSer: 3.395 ± 0.018	2.191AsnThr: 2.191 ± 0.014	2.425AsnVal: 2.425 ± 0.015	0.479AsnTrp: 0.479 ± 0.005	1.21AsnTyr: 1.21 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	4.399ProAla: 4.399 ± 0.026	1.151ProCys: 1.151 ± 0.014	2.596ProAsp: 2.596 ± 0.015	3.881ProGlu: 3.881 ± 0.02	1.818ProPhe: 1.818 ± 0.013	4.182ProGly: 4.182 ± 0.042	1.431ProHis: 1.431 ± 0.014	1.954ProIle: 1.954 ± 0.011	2.648ProLys: 2.648 ± 0.016	4.836ProLeu: 4.836 ± 0.024	1.012ProMet: 1.012 ± 0.01	1.893ProAsn: 1.893 ± 0.014	5.174ProPro: 5.174 ± 0.046	2.523ProGln: 2.523 ± 0.019	2.908ProArg: 2.908 ± 0.02	5.208ProSer: 5.208 ± 0.027	2.807ProThr: 2.807 ± 0.018	3.65ProVal: 3.65 ± 0.019	0.599ProTrp: 0.599 ± 0.007	1.413ProTyr: 1.413 ± 0.01	0.001ProXaa: 0.001 ± 0.0
Gln	3.15GlnAla: 3.15 ± 0.022	1.056GlnCys: 1.056 ± 0.012	2.207GlnAsp: 2.207 ± 0.013	3.725GlnGlu: 3.725 ± 0.026	1.414GlnPhe: 1.414 ± 0.009	2.552GlnGly: 2.552 ± 0.015	1.379GlnHis: 1.379 ± 0.01	2.167GlnIle: 2.167 ± 0.013	3.071GlnLys: 3.071 ± 0.021	4.727GlnLeu: 4.727 ± 0.028	1.129GlnMet: 1.129 ± 0.01	1.971GlnAsn: 1.971 ± 0.011	2.606GlnPro: 2.606 ± 0.02	3.17GlnGln: 3.17 ± 0.03	2.801GlnArg: 2.801 ± 0.017	3.243GlnSer: 3.243 ± 0.02	2.32GlnThr: 2.32 ± 0.014	2.705GlnVal: 2.705 ± 0.015	0.57GlnTrp: 0.57 ± 0.007	1.249GlnTyr: 1.249 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.697ArgAla: 3.697 ± 0.021	1.327ArgCys: 1.327 ± 0.016	2.668ArgAsp: 2.668 ± 0.015	3.777ArgGlu: 3.777 ± 0.022	1.846ArgPhe: 1.846 ± 0.011	3.41ArgGly: 3.41 ± 0.022	1.419ArgHis: 1.419 ± 0.01	2.543ArgIle: 2.543 ± 0.012	3.598ArgLys: 3.598 ± 0.017	4.963ArgLeu: 4.963 ± 0.021	1.216ArgMet: 1.216 ± 0.008	2.214ArgAsn: 2.214 ± 0.012	2.784ArgPro: 2.784 ± 0.019	2.552ArgGln: 2.552 ± 0.014	4.22ArgArg: 4.22 ± 0.025	4.239ArgSer: 4.239 ± 0.025	2.787ArgThr: 2.787 ± 0.012	2.999ArgVal: 2.999 ± 0.014	0.7ArgTrp: 0.7 ± 0.007	1.519ArgTyr: 1.519 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	5.522SerAla: 5.522 ± 0.022	1.929SerCys: 1.929 ± 0.014	4.059SerAsp: 4.059 ± 0.023	5.219SerGlu: 5.219 ± 0.022	3.105SerPhe: 3.105 ± 0.014	5.244SerGly: 5.244 ± 0.025	2.023SerHis: 2.023 ± 0.012	3.592SerIle: 3.592 ± 0.017	4.311SerLys: 4.311 ± 0.02	7.92SerLeu: 7.92 ± 0.028	1.677SerMet: 1.677 ± 0.011	2.976SerAsn: 2.976 ± 0.016	5.501SerPro: 5.501 ± 0.033	3.684SerGln: 3.684 ± 0.021	4.25SerArg: 4.25 ± 0.022	9.374SerSer: 9.374 ± 0.055	4.622SerThr: 4.622 ± 0.025	5.074SerVal: 5.074 ± 0.023	0.995SerTrp: 0.995 ± 0.008	2.162SerTyr: 2.162 ± 0.014	0.0SerXaa: 0.0 ± 0.0
Thr	4.012ThrAla: 4.012 ± 0.015	1.322ThrCys: 1.322 ± 0.017	2.718ThrAsp: 2.718 ± 0.013	3.732ThrGlu: 3.732 ± 0.018	2.083ThrPhe: 2.083 ± 0.014	3.443ThrGly: 3.443 ± 0.018	1.167ThrHis: 1.167 ± 0.008	2.503ThrIle: 2.503 ± 0.015	2.791ThrLys: 2.791 ± 0.016	5.003ThrLeu: 5.003 ± 0.018	1.112ThrMet: 1.112 ± 0.009	1.898ThrAsn: 1.898 ± 0.013	3.181ThrPro: 3.181 ± 0.022	2.134ThrGln: 2.134 ± 0.014	2.321ThrArg: 2.321 ± 0.013	4.595ThrSer: 4.595 ± 0.023	2.937ThrThr: 2.937 ± 0.022	3.97ThrVal: 3.97 ± 0.019	0.663ThrTrp: 0.663 ± 0.007	1.486ThrTyr: 1.486 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	4.063ValAla: 4.063 ± 0.018	1.516ValCys: 1.516 ± 0.011	2.915ValAsp: 2.915 ± 0.016	3.917ValGlu: 3.917 ± 0.019	2.48ValPhe: 2.48 ± 0.015	3.381ValGly: 3.381 ± 0.021	1.482ValHis: 1.482 ± 0.009	3.047ValIle: 3.047 ± 0.016	3.643ValLys: 3.643 ± 0.017	6.315ValLeu: 6.315 ± 0.029	1.38ValMet: 1.38 ± 0.01	2.48ValAsn: 2.48 ± 0.014	3.594ValPro: 3.594 ± 0.02	2.809ValGln: 2.809 ± 0.016	3.06ValArg: 3.06 ± 0.015	4.947ValSer: 4.947 ± 0.021	3.759ValThr: 3.759 ± 0.022	4.018ValVal: 4.018 ± 0.022	0.723ValTrp: 0.723 ± 0.007	1.678ValTyr: 1.678 ± 0.012	0.0ValXaa: 0.0 ± 0.0
Trp	0.708TrpAla: 0.708 ± 0.007	0.26TrpCys: 0.26 ± 0.005	0.66TrpAsp: 0.66 ± 0.009	0.797TrpGlu: 0.797 ± 0.008	0.436TrpPhe: 0.436 ± 0.005	0.752TrpGly: 0.752 ± 0.011	0.318TrpHis: 0.318 ± 0.005	0.617TrpIle: 0.617 ± 0.008	0.851TrpLys: 0.851 ± 0.007	1.239TrpLeu: 1.239 ± 0.01	0.331TrpMet: 0.331 ± 0.005	0.575TrpAsn: 0.575 ± 0.007	0.468TrpPro: 0.468 ± 0.006	0.549TrpGln: 0.549 ± 0.006	0.709TrpArg: 0.709 ± 0.008	0.874TrpSer: 0.874 ± 0.009	0.628TrpThr: 0.628 ± 0.007	0.688TrpVal: 0.688 ± 0.008	0.197TrpTrp: 0.197 ± 0.004	0.35TrpTyr: 0.35 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.491TyrAla: 1.491 ± 0.011	0.726TyrCys: 0.726 ± 0.008	1.393TyrAsp: 1.393 ± 0.01	1.755TyrGlu: 1.755 ± 0.012	1.306TyrPhe: 1.306 ± 0.011	1.773TyrGly: 1.773 ± 0.014	0.764TyrHis: 0.764 ± 0.007	1.543TyrIle: 1.543 ± 0.01	1.626TyrLys: 1.626 ± 0.016	2.698TyrLeu: 2.698 ± 0.013	0.629TyrMet: 0.629 ± 0.006	1.205TyrAsn: 1.205 ± 0.009	1.27TyrPro: 1.27 ± 0.01	1.239TyrGln: 1.239 ± 0.009	1.655TyrArg: 1.655 ± 0.012	2.303TyrSer: 2.303 ± 0.014	1.547TyrThr: 1.547 ± 0.012	1.607TyrVal: 1.607 ± 0.011	0.39TyrTrp: 0.39 ± 0.008	1.002TyrTyr: 1.002 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.3XaaXaa: 0.3 ± 0.086

Statistics based on 25507 proteins (17908591 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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