Amino acid dipepetide frequency for Hubei picorna-like virus 54

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.901AlaAla: 4.901 ± 0.0
2.018AlaCys: 2.018 ± 0.0
1.73AlaAsp: 1.73 ± 0.0
2.018AlaGlu: 2.018 ± 0.0
4.901AlaPhe: 4.901 ± 0.0
3.459AlaGly: 3.459 ± 0.0
0.865AlaHis: 0.865 ± 0.0
3.747AlaIle: 3.747 ± 0.0
4.901AlaLys: 4.901 ± 0.0
4.901AlaLeu: 4.901 ± 0.0
1.441AlaMet: 1.441 ± 0.0
4.612AlaAsn: 4.612 ± 0.0
2.306AlaPro: 2.306 ± 0.0
3.459AlaGln: 3.459 ± 0.0
1.441AlaArg: 1.441 ± 0.0
4.612AlaSer: 4.612 ± 0.0
6.054AlaThr: 6.054 ± 0.0
2.883AlaVal: 2.883 ± 0.0
0.288AlaTrp: 0.288 ± 0.0
2.883AlaTyr: 2.883 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.577CysAla: 0.577 ± 0.0
0.577CysCys: 0.577 ± 0.0
0.577CysAsp: 0.577 ± 0.0
0.577CysGlu: 0.577 ± 0.0
0.865CysPhe: 0.865 ± 0.0
0.865CysGly: 0.865 ± 0.0
0.288CysHis: 0.288 ± 0.0
0.577CysIle: 0.577 ± 0.0
1.441CysLys: 1.441 ± 0.0
1.73CysLeu: 1.73 ± 0.0
0.288CysMet: 0.288 ± 0.0
1.153CysAsn: 1.153 ± 0.0
0.288CysPro: 0.288 ± 0.0
0.865CysGln: 0.865 ± 0.0
0.577CysArg: 0.577 ± 0.0
1.441CysSer: 1.441 ± 0.0
1.153CysThr: 1.153 ± 0.0
0.577CysVal: 0.577 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.865CysTyr: 0.865 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.594AspAla: 2.594 ± 0.0
0.288AspCys: 0.288 ± 0.0
2.883AspAsp: 2.883 ± 0.0
2.594AspGlu: 2.594 ± 0.0
4.901AspPhe: 4.901 ± 0.0
3.171AspGly: 3.171 ± 0.0
1.73AspHis: 1.73 ± 0.0
4.901AspIle: 4.901 ± 0.0
4.036AspLys: 4.036 ± 0.0
4.324AspLeu: 4.324 ± 0.0
1.153AspMet: 1.153 ± 0.0
2.018AspAsn: 2.018 ± 0.0
2.306AspPro: 2.306 ± 0.0
1.441AspGln: 1.441 ± 0.0
1.441AspArg: 1.441 ± 0.0
3.747AspSer: 3.747 ± 0.0
1.73AspThr: 1.73 ± 0.0
3.747AspVal: 3.747 ± 0.0
1.441AspTrp: 1.441 ± 0.0
3.171AspTyr: 3.171 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.612GluAla: 4.612 ± 0.0
0.865GluCys: 0.865 ± 0.0
2.306GluAsp: 2.306 ± 0.0
4.324GluGlu: 4.324 ± 0.0
4.324GluPhe: 4.324 ± 0.0
3.171GluGly: 3.171 ± 0.0
0.288GluHis: 0.288 ± 0.0
6.054GluIle: 6.054 ± 0.0
4.324GluLys: 4.324 ± 0.0
5.189GluLeu: 5.189 ± 0.0
0.865GluMet: 0.865 ± 0.0
3.459GluAsn: 3.459 ± 0.0
1.441GluPro: 1.441 ± 0.0
2.018GluGln: 2.018 ± 0.0
2.018GluArg: 2.018 ± 0.0
1.73GluSer: 1.73 ± 0.0
3.747GluThr: 3.747 ± 0.0
3.459GluVal: 3.459 ± 0.0
0.0GluTrp: 0.0 ± 0.0
2.883GluTyr: 2.883 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.459PheAla: 3.459 ± 0.0
0.577PheCys: 0.577 ± 0.0
2.883PheAsp: 2.883 ± 0.0
2.883PheGlu: 2.883 ± 0.0
2.594PhePhe: 2.594 ± 0.0
1.73PheGly: 1.73 ± 0.0
0.865PheHis: 0.865 ± 0.0
4.036PheIle: 4.036 ± 0.0
5.189PheLys: 5.189 ± 0.0
2.306PheLeu: 2.306 ± 0.0
1.153PheMet: 1.153 ± 0.0
2.883PheAsn: 2.883 ± 0.0
3.459PhePro: 3.459 ± 0.0
1.73PheGln: 1.73 ± 0.0
1.441PheArg: 1.441 ± 0.0
4.324PheSer: 4.324 ± 0.0
3.747PheThr: 3.747 ± 0.0
1.73PheVal: 1.73 ± 0.0
0.0PheTrp: 0.0 ± 0.0
2.018PheTyr: 2.018 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.883GlyAla: 2.883 ± 0.0
1.153GlyCys: 1.153 ± 0.0
4.036GlyAsp: 4.036 ± 0.0
1.441GlyGlu: 1.441 ± 0.0
1.73GlyPhe: 1.73 ± 0.0
2.306GlyGly: 2.306 ± 0.0
0.865GlyHis: 0.865 ± 0.0
5.477GlyIle: 5.477 ± 0.0
3.747GlyLys: 3.747 ± 0.0
5.189GlyLeu: 5.189 ± 0.0
1.153GlyMet: 1.153 ± 0.0
4.036GlyAsn: 4.036 ± 0.0
1.153GlyPro: 1.153 ± 0.0
2.594GlyGln: 2.594 ± 0.0
0.865GlyArg: 0.865 ± 0.0
5.477GlySer: 5.477 ± 0.0
3.459GlyThr: 3.459 ± 0.0
2.018GlyVal: 2.018 ± 0.0
1.441GlyTrp: 1.441 ± 0.0
1.441GlyTyr: 1.441 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.153HisAla: 1.153 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.865HisAsp: 0.865 ± 0.0
1.153HisGlu: 1.153 ± 0.0
1.441HisPhe: 1.441 ± 0.0
0.865HisGly: 0.865 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.594HisIle: 2.594 ± 0.0
1.153HisLys: 1.153 ± 0.0
3.171HisLeu: 3.171 ± 0.0
0.288HisMet: 0.288 ± 0.0
1.73HisAsn: 1.73 ± 0.0
1.73HisPro: 1.73 ± 0.0
1.153HisGln: 1.153 ± 0.0
0.865HisArg: 0.865 ± 0.0
0.577HisSer: 0.577 ± 0.0
1.441HisThr: 1.441 ± 0.0
1.441HisVal: 1.441 ± 0.0
0.288HisTrp: 0.288 ± 0.0
0.865HisTyr: 0.865 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.324IleAla: 4.324 ± 0.0
1.441IleCys: 1.441 ± 0.0
3.459IleAsp: 3.459 ± 0.0
4.901IleGlu: 4.901 ± 0.0
3.459IlePhe: 3.459 ± 0.0
4.324IleGly: 4.324 ± 0.0
1.73IleHis: 1.73 ± 0.0
4.901IleIle: 4.901 ± 0.0
6.63IleLys: 6.63 ± 0.0
7.207IleLeu: 7.207 ± 0.0
2.018IleMet: 2.018 ± 0.0
4.036IleAsn: 4.036 ± 0.0
2.594IlePro: 2.594 ± 0.0
3.747IleGln: 3.747 ± 0.0
2.883IleArg: 2.883 ± 0.0
5.477IleSer: 5.477 ± 0.0
7.207IleThr: 7.207 ± 0.0
5.765IleVal: 5.765 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.73IleTyr: 1.73 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.901LysAla: 4.901 ± 0.0
0.865LysCys: 0.865 ± 0.0
5.477LysAsp: 5.477 ± 0.0
3.747LysGlu: 3.747 ± 0.0
2.306LysPhe: 2.306 ± 0.0
2.594LysGly: 2.594 ± 0.0
2.594LysHis: 2.594 ± 0.0
4.612LysIle: 4.612 ± 0.0
4.036LysLys: 4.036 ± 0.0
9.513LysLeu: 9.513 ± 0.0
1.153LysMet: 1.153 ± 0.0
3.171LysAsn: 3.171 ± 0.0
3.747LysPro: 3.747 ± 0.0
2.306LysGln: 2.306 ± 0.0
3.459LysArg: 3.459 ± 0.0
3.459LysSer: 3.459 ± 0.0
6.054LysThr: 6.054 ± 0.0
2.594LysVal: 2.594 ± 0.0
0.288LysTrp: 0.288 ± 0.0
3.747LysTyr: 3.747 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.342LeuAla: 6.342 ± 0.0
2.018LeuCys: 2.018 ± 0.0
5.765LeuAsp: 5.765 ± 0.0
4.612LeuGlu: 4.612 ± 0.0
4.324LeuPhe: 4.324 ± 0.0
3.459LeuGly: 3.459 ± 0.0
2.883LeuHis: 2.883 ± 0.0
6.918LeuIle: 6.918 ± 0.0
7.495LeuLys: 7.495 ± 0.0
8.071LeuLeu: 8.071 ± 0.0
1.441LeuMet: 1.441 ± 0.0
4.612LeuAsn: 4.612 ± 0.0
4.324LeuPro: 4.324 ± 0.0
6.054LeuGln: 6.054 ± 0.0
1.73LeuArg: 1.73 ± 0.0
5.477LeuSer: 5.477 ± 0.0
10.089LeuThr: 10.089 ± 0.0
4.324LeuVal: 4.324 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
3.171LeuTyr: 3.171 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.577MetAla: 0.577 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.73MetAsp: 1.73 ± 0.0
1.73MetGlu: 1.73 ± 0.0
2.306MetPhe: 2.306 ± 0.0
1.441MetGly: 1.441 ± 0.0
0.288MetHis: 0.288 ± 0.0
0.288MetIle: 0.288 ± 0.0
1.73MetLys: 1.73 ± 0.0
2.594MetLeu: 2.594 ± 0.0
0.865MetMet: 0.865 ± 0.0
2.594MetAsn: 2.594 ± 0.0
1.153MetPro: 1.153 ± 0.0
0.865MetGln: 0.865 ± 0.0
0.865MetArg: 0.865 ± 0.0
1.73MetSer: 1.73 ± 0.0
1.153MetThr: 1.153 ± 0.0
0.577MetVal: 0.577 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.288MetTyr: 0.288 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.459AsnAla: 3.459 ± 0.0
0.577AsnCys: 0.577 ± 0.0
2.306AsnAsp: 2.306 ± 0.0
3.171AsnGlu: 3.171 ± 0.0
2.018AsnPhe: 2.018 ± 0.0
2.018AsnGly: 2.018 ± 0.0
1.441AsnHis: 1.441 ± 0.0
3.747AsnIle: 3.747 ± 0.0
2.594AsnLys: 2.594 ± 0.0
5.189AsnLeu: 5.189 ± 0.0
1.441AsnMet: 1.441 ± 0.0
1.73AsnAsn: 1.73 ± 0.0
2.306AsnPro: 2.306 ± 0.0
2.594AsnGln: 2.594 ± 0.0
2.883AsnArg: 2.883 ± 0.0
3.171AsnSer: 3.171 ± 0.0
4.036AsnThr: 4.036 ± 0.0
3.747AsnVal: 3.747 ± 0.0
0.577AsnTrp: 0.577 ± 0.0
2.018AsnTyr: 2.018 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.018ProAla: 2.018 ± 0.0
0.288ProCys: 0.288 ± 0.0
3.171ProAsp: 3.171 ± 0.0
3.171ProGlu: 3.171 ± 0.0
1.441ProPhe: 1.441 ± 0.0
2.594ProGly: 2.594 ± 0.0
0.288ProHis: 0.288 ± 0.0
4.324ProIle: 4.324 ± 0.0
3.171ProLys: 3.171 ± 0.0
3.171ProLeu: 3.171 ± 0.0
0.577ProMet: 0.577 ± 0.0
1.441ProAsn: 1.441 ± 0.0
1.153ProPro: 1.153 ± 0.0
2.018ProGln: 2.018 ± 0.0
1.153ProArg: 1.153 ± 0.0
4.324ProSer: 4.324 ± 0.0
3.747ProThr: 3.747 ± 0.0
1.441ProVal: 1.441 ± 0.0
0.577ProTrp: 0.577 ± 0.0
2.018ProTyr: 2.018 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.747GlnAla: 3.747 ± 0.0
0.577GlnCys: 0.577 ± 0.0
1.73GlnAsp: 1.73 ± 0.0
4.036GlnGlu: 4.036 ± 0.0
1.73GlnPhe: 1.73 ± 0.0
4.036GlnGly: 4.036 ± 0.0
1.153GlnHis: 1.153 ± 0.0
6.918GlnIle: 6.918 ± 0.0
2.306GlnLys: 2.306 ± 0.0
4.901GlnLeu: 4.901 ± 0.0
1.73GlnMet: 1.73 ± 0.0
2.306GlnAsn: 2.306 ± 0.0
1.73GlnPro: 1.73 ± 0.0
3.171GlnGln: 3.171 ± 0.0
2.018GlnArg: 2.018 ± 0.0
3.171GlnSer: 3.171 ± 0.0
1.73GlnThr: 1.73 ± 0.0
1.153GlnVal: 1.153 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.577GlnTyr: 0.577 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.73ArgAla: 1.73 ± 0.0
0.577ArgCys: 0.577 ± 0.0
2.594ArgAsp: 2.594 ± 0.0
2.594ArgGlu: 2.594 ± 0.0
2.594ArgPhe: 2.594 ± 0.0
1.153ArgGly: 1.153 ± 0.0
0.577ArgHis: 0.577 ± 0.0
2.883ArgIle: 2.883 ± 0.0
1.153ArgLys: 1.153 ± 0.0
3.747ArgLeu: 3.747 ± 0.0
0.865ArgMet: 0.865 ± 0.0
1.153ArgAsn: 1.153 ± 0.0
1.441ArgPro: 1.441 ± 0.0
1.153ArgGln: 1.153 ± 0.0
2.018ArgArg: 2.018 ± 0.0
2.018ArgSer: 2.018 ± 0.0
3.171ArgThr: 3.171 ± 0.0
2.306ArgVal: 2.306 ± 0.0
0.577ArgTrp: 0.577 ± 0.0
1.441ArgTyr: 1.441 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.594SerAla: 2.594 ± 0.0
0.865SerCys: 0.865 ± 0.0
2.883SerAsp: 2.883 ± 0.0
3.171SerGlu: 3.171 ± 0.0
2.883SerPhe: 2.883 ± 0.0
4.612SerGly: 4.612 ± 0.0
2.594SerHis: 2.594 ± 0.0
4.036SerIle: 4.036 ± 0.0
4.324SerLys: 4.324 ± 0.0
6.342SerLeu: 6.342 ± 0.0
1.441SerMet: 1.441 ± 0.0
3.459SerAsn: 3.459 ± 0.0
2.306SerPro: 2.306 ± 0.0
5.765SerGln: 5.765 ± 0.0
4.036SerArg: 4.036 ± 0.0
6.342SerSer: 6.342 ± 0.0
7.207SerThr: 7.207 ± 0.0
2.306SerVal: 2.306 ± 0.0
1.441SerTrp: 1.441 ± 0.0
1.441SerTyr: 1.441 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.63ThrAla: 6.63 ± 0.0
1.73ThrCys: 1.73 ± 0.0
3.747ThrAsp: 3.747 ± 0.0
4.036ThrGlu: 4.036 ± 0.0
2.306ThrPhe: 2.306 ± 0.0
6.054ThrGly: 6.054 ± 0.0
2.018ThrHis: 2.018 ± 0.0
4.612ThrIle: 4.612 ± 0.0
5.477ThrLys: 5.477 ± 0.0
7.207ThrLeu: 7.207 ± 0.0
1.73ThrMet: 1.73 ± 0.0
2.594ThrAsn: 2.594 ± 0.0
4.612ThrPro: 4.612 ± 0.0
4.612ThrGln: 4.612 ± 0.0
2.883ThrArg: 2.883 ± 0.0
5.189ThrSer: 5.189 ± 0.0
7.783ThrThr: 7.783 ± 0.0
4.036ThrVal: 4.036 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
2.594ThrTyr: 2.594 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.036ValAla: 4.036 ± 0.0
0.865ValCys: 0.865 ± 0.0
3.171ValAsp: 3.171 ± 0.0
3.459ValGlu: 3.459 ± 0.0
1.153ValPhe: 1.153 ± 0.0
2.018ValGly: 2.018 ± 0.0
1.153ValHis: 1.153 ± 0.0
4.036ValIle: 4.036 ± 0.0
2.883ValLys: 2.883 ± 0.0
4.036ValLeu: 4.036 ± 0.0
1.153ValMet: 1.153 ± 0.0
1.73ValAsn: 1.73 ± 0.0
2.594ValPro: 2.594 ± 0.0
2.594ValGln: 2.594 ± 0.0
0.865ValArg: 0.865 ± 0.0
4.324ValSer: 4.324 ± 0.0
3.747ValThr: 3.747 ± 0.0
2.018ValVal: 2.018 ± 0.0
0.577ValTrp: 0.577 ± 0.0
2.594ValTyr: 2.594 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.577TrpAla: 0.577 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.577TrpAsp: 0.577 ± 0.0
0.288TrpGlu: 0.288 ± 0.0
0.577TrpPhe: 0.577 ± 0.0
0.577TrpGly: 0.577 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.288TrpIle: 0.288 ± 0.0
0.865TrpLys: 0.865 ± 0.0
0.288TrpLeu: 0.288 ± 0.0
0.288TrpMet: 0.288 ± 0.0
0.577TrpAsn: 0.577 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.577TrpGln: 0.577 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.577TrpSer: 0.577 ± 0.0
0.865TrpThr: 0.865 ± 0.0
0.288TrpVal: 0.288 ± 0.0
0.288TrpTrp: 0.288 ± 0.0
0.865TrpTyr: 0.865 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.306TyrAla: 2.306 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.73TyrAsp: 1.73 ± 0.0
3.171TyrGlu: 3.171 ± 0.0
1.153TyrPhe: 1.153 ± 0.0
2.018TyrGly: 2.018 ± 0.0
1.153TyrHis: 1.153 ± 0.0
2.883TyrIle: 2.883 ± 0.0
3.171TyrLys: 3.171 ± 0.0
4.036TyrLeu: 4.036 ± 0.0
1.441TyrMet: 1.441 ± 0.0
1.73TyrAsn: 1.73 ± 0.0
1.441TyrPro: 1.441 ± 0.0
0.288TyrGln: 0.288 ± 0.0
2.306TyrArg: 2.306 ± 0.0
2.883TyrSer: 2.883 ± 0.0
1.73TyrThr: 1.73 ± 0.0
2.594TyrVal: 2.594 ± 0.0
0.577TyrTrp: 0.577 ± 0.0
0.577TyrTyr: 0.577 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3470 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski