Amino acid dipepetide frequency for Parana mammarenavirus (isolate Rat/Paraguay/12056/1965) (PARV) (Paran mammarenavirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.272AlaAla: 3.272 ± 0.587
1.785AlaCys: 1.785 ± 0.905
1.487AlaAsp: 1.487 ± 0.511
1.19AlaGlu: 1.19 ± 0.635
1.785AlaPhe: 1.785 ± 0.64
3.272AlaGly: 3.272 ± 1.511
0.297AlaHis: 0.297 ± 0.155
2.974AlaIle: 2.974 ± 1.127
2.082AlaLys: 2.082 ± 0.665
6.544AlaLeu: 6.544 ± 1.637
0.297AlaMet: 0.297 ± 0.155
1.19AlaAsn: 1.19 ± 0.743
1.785AlaPro: 1.785 ± 0.905
0.892AlaGln: 0.892 ± 0.85
2.38AlaArg: 2.38 ± 0.97
0.595AlaSer: 0.595 ± 0.372
2.082AlaThr: 2.082 ± 1.696
3.569AlaVal: 3.569 ± 1.39
0.595AlaTrp: 0.595 ± 0.573
1.785AlaTyr: 1.785 ± 0.643
0.0AlaXaa: 0.0 ± 0.0
Cys
0.297CysAla: 0.297 ± 0.378
0.297CysCys: 0.297 ± 0.155
1.487CysAsp: 1.487 ± 1.201
2.38CysGlu: 2.38 ± 0.686
2.38CysPhe: 2.38 ± 0.993
1.487CysGly: 1.487 ± 1.303
0.892CysHis: 0.892 ± 0.464
1.487CysIle: 1.487 ± 0.702
1.785CysLys: 1.785 ± 0.806
4.164CysLeu: 4.164 ± 1.523
0.595CysMet: 0.595 ± 0.756
0.892CysAsn: 0.892 ± 0.833
0.892CysPro: 0.892 ± 0.322
0.0CysGln: 0.0 ± 0.0
1.487CysArg: 1.487 ± 0.421
2.38CysSer: 2.38 ± 2.024
0.595CysThr: 0.595 ± 0.309
1.487CysVal: 1.487 ± 0.773
0.595CysTrp: 0.595 ± 1.163
0.892CysTyr: 0.892 ± 0.326
0.0CysXaa: 0.0 ± 0.0
Asp
1.487AspAla: 1.487 ± 0.993
1.19AspCys: 1.19 ± 0.4
3.867AspAsp: 3.867 ± 0.773
4.759AspGlu: 4.759 ± 2.128
3.569AspPhe: 3.569 ± 0.997
2.974AspGly: 2.974 ± 1.514
1.785AspHis: 1.785 ± 0.837
4.462AspIle: 4.462 ± 0.49
3.569AspLys: 3.569 ± 0.991
7.139AspLeu: 7.139 ± 2.609
2.677AspMet: 2.677 ± 0.541
1.487AspAsn: 1.487 ± 0.163
2.082AspPro: 2.082 ± 0.713
1.487AspGln: 1.487 ± 0.511
2.082AspArg: 2.082 ± 0.762
3.272AspSer: 3.272 ± 0.708
1.19AspThr: 1.19 ± 0.743
4.164AspVal: 4.164 ± 1.592
1.487AspTrp: 1.487 ± 0.421
2.38AspTyr: 2.38 ± 0.804
0.0AspXaa: 0.0 ± 0.0
Glu
1.785GluAla: 1.785 ± 0.643
2.38GluCys: 2.38 ± 1.236
2.974GluAsp: 2.974 ± 1.022
6.246GluGlu: 6.246 ± 1.626
2.677GluPhe: 2.677 ± 0.751
3.272GluGly: 3.272 ± 1.532
1.487GluHis: 1.487 ± 0.511
3.569GluIle: 3.569 ± 1.075
3.867GluLys: 3.867 ± 1.568
6.841GluLeu: 6.841 ± 1.299
1.785GluMet: 1.785 ± 0.889
2.082GluAsn: 2.082 ± 0.472
1.19GluPro: 1.19 ± 0.4
4.164GluGln: 4.164 ± 1.287
2.082GluArg: 2.082 ± 0.665
5.651GluSer: 5.651 ± 0.617
2.974GluThr: 2.974 ± 0.66
5.949GluVal: 5.949 ± 1.698
0.595GluTrp: 0.595 ± 0.309
1.785GluTyr: 1.785 ± 0.535
0.0GluXaa: 0.0 ± 0.0
Phe
1.19PheAla: 1.19 ± 0.757
0.595PheCys: 0.595 ± 1.163
2.677PheAsp: 2.677 ± 0.378
2.974PheGlu: 2.974 ± 0.881
1.785PhePhe: 1.785 ± 0.535
1.19PheGly: 1.19 ± 0.4
0.892PheHis: 0.892 ± 0.464
1.19PheIle: 1.19 ± 0.618
3.569PheLys: 3.569 ± 1.28
4.759PheLeu: 4.759 ± 1.608
1.19PheMet: 1.19 ± 0.618
4.164PheAsn: 4.164 ± 2.043
0.297PhePro: 0.297 ± 0.378
1.487PheGln: 1.487 ± 0.677
1.487PheArg: 1.487 ± 0.163
2.38PheSer: 2.38 ± 0.923
3.272PheThr: 3.272 ± 0.95
1.785PheVal: 1.785 ± 0.64
1.487PheTrp: 1.487 ± 0.677
1.785PheTyr: 1.785 ± 0.927
0.0PheXaa: 0.0 ± 0.0
Gly
1.785GlyAla: 1.785 ± 0.471
0.595GlyCys: 0.595 ± 0.372
3.569GlyAsp: 3.569 ± 0.723
2.974GlyGlu: 2.974 ± 0.474
2.974GlyPhe: 2.974 ± 0.842
3.569GlyGly: 3.569 ± 1.41
0.892GlyHis: 0.892 ± 0.322
3.569GlyIle: 3.569 ± 1.721
2.677GlyLys: 2.677 ± 1.984
7.139GlyLeu: 7.139 ± 3.045
1.785GlyMet: 1.785 ± 0.797
3.569GlyAsn: 3.569 ± 1.607
2.38GlyPro: 2.38 ± 0.753
2.082GlyGln: 2.082 ± 0.472
2.677GlyArg: 2.677 ± 2.062
3.272GlySer: 3.272 ± 1.002
2.974GlyThr: 2.974 ± 0.96
3.272GlyVal: 3.272 ± 1.109
0.297GlyTrp: 0.297 ± 0.378
2.677GlyTyr: 2.677 ± 0.962
0.0GlyXaa: 0.0 ± 0.0
His
0.892HisAla: 0.892 ± 0.326
0.892HisCys: 0.892 ± 0.85
0.0HisAsp: 0.0 ± 0.0
0.892HisGlu: 0.892 ± 0.464
0.892HisPhe: 0.892 ± 0.833
0.892HisGly: 0.892 ± 0.681
1.19HisHis: 1.19 ± 0.341
2.677HisIle: 2.677 ± 0.751
1.785HisLys: 1.785 ± 0.535
2.38HisLeu: 2.38 ± 0.804
0.595HisMet: 0.595 ± 0.309
2.082HisAsn: 2.082 ± 0.389
0.892HisPro: 0.892 ± 0.326
0.0HisGln: 0.0 ± 0.0
0.595HisArg: 0.595 ± 0.939
1.487HisSer: 1.487 ± 0.421
1.785HisThr: 1.785 ± 0.146
1.19HisVal: 1.19 ± 0.743
0.0HisTrp: 0.0 ± 0.0
1.19HisTyr: 1.19 ± 1.411
0.0HisXaa: 0.0 ± 0.0
Ile
2.677IleAla: 2.677 ± 1.984
1.487IleCys: 1.487 ± 0.421
4.164IleAsp: 4.164 ± 0.984
5.057IleGlu: 5.057 ± 0.558
1.19IlePhe: 1.19 ± 0.341
2.38IleGly: 2.38 ± 0.399
0.892IleHis: 0.892 ± 0.464
4.164IleIle: 4.164 ± 0.591
5.651IleLys: 5.651 ± 1.342
5.949IleLeu: 5.949 ± 2.228
2.38IleMet: 2.38 ± 0.863
2.38IleAsn: 2.38 ± 1.894
3.867IlePro: 3.867 ± 1.063
2.38IleGln: 2.38 ± 0.683
3.867IleArg: 3.867 ± 0.517
6.246IleSer: 6.246 ± 0.759
2.677IleThr: 2.677 ± 0.378
3.569IleVal: 3.569 ± 1.112
0.297IleTrp: 0.297 ± 0.155
0.892IleTyr: 0.892 ± 0.326
0.0IleXaa: 0.0 ± 0.0
Lys
3.272LysAla: 3.272 ± 1.275
2.677LysCys: 2.677 ± 1.414
5.354LysAsp: 5.354 ± 1.53
4.759LysGlu: 4.759 ± 1.09
3.569LysPhe: 3.569 ± 0.997
5.057LysGly: 5.057 ± 0.726
1.19LysHis: 1.19 ± 0.4
3.569LysIle: 3.569 ± 1.425
3.867LysLys: 3.867 ± 1.535
8.626LysLeu: 8.626 ± 1.832
0.892LysMet: 0.892 ± 0.408
3.569LysAsn: 3.569 ± 0.715
2.082LysPro: 2.082 ± 0.703
2.082LysGln: 2.082 ± 0.253
5.057LysArg: 5.057 ± 0.905
4.759LysSer: 4.759 ± 2.128
3.569LysThr: 3.569 ± 1.229
5.057LysVal: 5.057 ± 1.217
0.892LysTrp: 0.892 ± 0.322
2.974LysTyr: 2.974 ± 1.174
0.0LysXaa: 0.0 ± 0.0
Leu
3.569LeuAla: 3.569 ± 1.124
5.057LeuCys: 5.057 ± 0.558
8.328LeuAsp: 8.328 ± 3.645
7.139LeuGlu: 7.139 ± 0.874
3.569LeuPhe: 3.569 ± 0.618
4.759LeuGly: 4.759 ± 1.612
2.082LeuHis: 2.082 ± 0.472
9.816LeuIle: 9.816 ± 0.285
10.41LeuLys: 10.41 ± 2.837
11.898LeuLeu: 11.898 ± 1.575
3.867LeuMet: 3.867 ± 1.793
8.031LeuAsn: 8.031 ± 1.418
2.974LeuPro: 2.974 ± 1.799
2.974LeuGln: 2.974 ± 0.418
5.354LeuArg: 5.354 ± 1.488
11.898LeuSer: 11.898 ± 3.553
8.328LeuThr: 8.328 ± 2.417
6.544LeuVal: 6.544 ± 1.328
0.892LeuTrp: 0.892 ± 0.322
2.974LeuTyr: 2.974 ± 0.628
0.0LeuXaa: 0.0 ± 0.0
Met
1.785MetAla: 1.785 ± 0.643
0.595MetCys: 0.595 ± 0.372
2.082MetAsp: 2.082 ± 0.779
1.487MetGlu: 1.487 ± 0.773
1.487MetPhe: 1.487 ± 1.059
1.785MetGly: 1.785 ± 0.859
0.297MetHis: 0.297 ± 0.378
2.38MetIle: 2.38 ± 0.799
2.082MetLys: 2.082 ± 0.253
2.082MetLeu: 2.082 ± 0.762
0.0MetMet: 0.0 ± 0.0
1.487MetAsn: 1.487 ± 0.625
0.297MetPro: 0.297 ± 0.378
0.297MetGln: 0.297 ± 0.155
0.892MetArg: 0.892 ± 0.85
4.759MetSer: 4.759 ± 0.418
2.082MetThr: 2.082 ± 0.706
1.19MetVal: 1.19 ± 0.4
0.0MetTrp: 0.0 ± 0.0
0.297MetTyr: 0.297 ± 0.155
0.0MetXaa: 0.0 ± 0.0
Asn
0.892AsnAla: 0.892 ± 0.322
2.082AsnCys: 2.082 ± 2.449
2.974AsnAsp: 2.974 ± 0.757
3.867AsnGlu: 3.867 ± 1.571
1.487AsnPhe: 1.487 ± 0.767
2.974AsnGly: 2.974 ± 1.405
1.19AsnHis: 1.19 ± 0.341
2.082AsnIle: 2.082 ± 1.04
4.164AsnLys: 4.164 ± 0.883
7.139AsnLeu: 7.139 ± 2.056
2.38AsnMet: 2.38 ± 0.393
1.785AsnAsn: 1.785 ± 1.115
3.569AsnPro: 3.569 ± 1.305
3.867AsnGln: 3.867 ± 0.966
2.082AsnArg: 2.082 ± 0.779
2.974AsnSer: 2.974 ± 0.96
2.677AsnThr: 2.677 ± 0.834
2.974AsnVal: 2.974 ± 0.692
0.892AsnTrp: 0.892 ± 0.424
2.38AsnTyr: 2.38 ± 0.93
0.0AsnXaa: 0.0 ± 0.0
Pro
1.487ProAla: 1.487 ± 0.993
0.595ProCys: 0.595 ± 0.317
2.677ProAsp: 2.677 ± 1.391
2.082ProGlu: 2.082 ± 0.472
0.595ProPhe: 0.595 ± 0.309
1.785ProGly: 1.785 ± 0.943
1.785ProHis: 1.785 ± 0.471
1.785ProIle: 1.785 ± 0.471
2.974ProLys: 2.974 ± 0.665
2.974ProLeu: 2.974 ± 1.022
1.19ProMet: 1.19 ± 1.422
2.38ProAsn: 2.38 ± 0.923
1.487ProPro: 1.487 ± 1.8
1.487ProGln: 1.487 ± 0.89
0.892ProArg: 0.892 ± 0.326
2.974ProSer: 2.974 ± 0.665
0.892ProThr: 0.892 ± 0.464
2.974ProVal: 2.974 ± 1.055
0.0ProTrp: 0.0 ± 0.0
1.487ProTyr: 1.487 ± 1.248
0.0ProXaa: 0.0 ± 0.0
Gln
0.892GlnAla: 0.892 ± 0.681
0.595GlnCys: 0.595 ± 0.372
1.487GlnAsp: 1.487 ± 0.773
2.677GlnGlu: 2.677 ± 0.904
1.487GlnPhe: 1.487 ± 0.511
2.974GlnGly: 2.974 ± 1.676
0.595GlnHis: 0.595 ± 0.756
2.974GlnIle: 2.974 ± 0.325
1.487GlnLys: 1.487 ± 0.511
5.949GlnLeu: 5.949 ± 1.513
0.297GlnMet: 0.297 ± 0.378
1.487GlnAsn: 1.487 ± 0.677
0.892GlnPro: 0.892 ± 0.326
0.595GlnGln: 0.595 ± 0.372
1.487GlnArg: 1.487 ± 0.993
3.867GlnSer: 3.867 ± 0.853
1.19GlnThr: 1.19 ± 0.618
2.677GlnVal: 2.677 ± 1.25
0.595GlnTrp: 0.595 ± 0.372
1.487GlnTyr: 1.487 ± 0.421
0.0GlnXaa: 0.0 ± 0.0
Arg
3.569ArgAla: 3.569 ± 2.006
1.19ArgCys: 1.19 ± 1.411
1.785ArgAsp: 1.785 ± 0.952
2.677ArgGlu: 2.677 ± 0.797
1.785ArgPhe: 1.785 ± 0.708
0.892ArgGly: 0.892 ± 0.326
1.785ArgHis: 1.785 ± 2.817
2.38ArgIle: 2.38 ± 0.399
2.974ArgLys: 2.974 ± 0.325
7.139ArgLeu: 7.139 ± 2.374
0.892ArgMet: 0.892 ± 0.833
3.569ArgAsn: 3.569 ± 0.687
1.19ArgPro: 1.19 ± 0.4
1.19ArgGln: 1.19 ± 0.282
2.677ArgArg: 2.677 ± 0.39
3.867ArgSer: 3.867 ± 0.449
1.487ArgThr: 1.487 ± 0.511
1.785ArgVal: 1.785 ± 0.652
1.19ArgTrp: 1.19 ± 0.282
1.487ArgTyr: 1.487 ± 0.744
0.0ArgXaa: 0.0 ± 0.0
Ser
4.164SerAla: 4.164 ± 2.322
1.487SerCys: 1.487 ± 0.677
4.462SerAsp: 4.462 ± 1.441
3.272SerGlu: 3.272 ± 1.109
1.785SerPhe: 1.785 ± 0.64
3.867SerGly: 3.867 ± 0.966
2.082SerHis: 2.082 ± 0.253
2.677SerIle: 2.677 ± 0.962
7.139SerLys: 7.139 ± 1.915
12.195SerLeu: 12.195 ± 2.949
3.272SerMet: 3.272 ± 1.148
3.867SerAsn: 3.867 ± 1.15
3.272SerPro: 3.272 ± 1.275
4.164SerGln: 4.164 ± 0.995
4.462SerArg: 4.462 ± 0.643
5.354SerSer: 5.354 ± 0.81
4.462SerThr: 4.462 ± 1.141
5.354SerVal: 5.354 ± 1.322
0.892SerTrp: 0.892 ± 0.464
2.082SerTyr: 2.082 ± 0.645
0.0SerXaa: 0.0 ± 0.0
Thr
2.082ThrAla: 2.082 ± 0.713
1.19ThrCys: 1.19 ± 0.341
3.272ThrAsp: 3.272 ± 0.505
2.974ThrGlu: 2.974 ± 0.474
1.785ThrPhe: 1.785 ± 0.927
1.785ThrGly: 1.785 ± 0.652
1.19ThrHis: 1.19 ± 1.3
2.974ThrIle: 2.974 ± 0.973
2.974ThrLys: 2.974 ± 0.974
6.246ThrLeu: 6.246 ± 1.715
1.487ThrMet: 1.487 ± 0.971
3.569ThrAsn: 3.569 ± 1.66
1.785ThrPro: 1.785 ± 0.535
2.082ThrGln: 2.082 ± 1.307
2.677ThrArg: 2.677 ± 0.378
2.974ThrSer: 2.974 ± 1.218
1.487ThrThr: 1.487 ± 0.702
3.867ThrVal: 3.867 ± 0.517
0.892ThrTrp: 0.892 ± 0.977
1.487ThrTyr: 1.487 ± 0.421
0.0ThrXaa: 0.0 ± 0.0
Val
2.677ValAla: 2.677 ± 0.834
0.595ValCys: 0.595 ± 0.828
2.082ValAsp: 2.082 ± 0.936
4.164ValGlu: 4.164 ± 1.304
2.677ValPhe: 2.677 ± 0.639
5.949ValGly: 5.949 ± 1.113
1.19ValHis: 1.19 ± 0.618
4.759ValIle: 4.759 ± 1.09
6.246ValLys: 6.246 ± 2.159
4.462ValLeu: 4.462 ± 0.972
1.487ValMet: 1.487 ± 0.421
4.164ValAsn: 4.164 ± 1.169
2.677ValPro: 2.677 ± 0.541
3.569ValGln: 3.569 ± 0.972
2.677ValArg: 2.677 ± 0.378
7.139ValSer: 7.139 ± 2.374
1.785ValThr: 1.785 ± 0.578
4.759ValVal: 4.759 ± 1.599
0.892ValTrp: 0.892 ± 0.85
2.38ValTyr: 2.38 ± 0.357
0.0ValXaa: 0.0 ± 0.0
Trp
1.19TrpAla: 1.19 ± 0.743
0.0TrpCys: 0.0 ± 0.0
1.487TrpAsp: 1.487 ± 1.059
0.595TrpGlu: 0.595 ± 0.372
0.297TrpPhe: 0.297 ± 0.902
0.595TrpGly: 0.595 ± 0.372
0.297TrpHis: 0.297 ± 0.155
0.297TrpIle: 0.297 ± 0.378
0.297TrpLys: 0.297 ± 0.47
2.38TrpLeu: 2.38 ± 0.993
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.595TrpPro: 0.595 ± 0.317
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.892TrpSer: 0.892 ± 0.322
0.595TrpThr: 0.595 ± 0.756
2.38TrpVal: 2.38 ± 0.683
0.0TrpTrp: 0.0 ± 0.0
0.595TrpTyr: 0.595 ± 0.372
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.892TyrAla: 0.892 ± 0.464
1.19TyrCys: 1.19 ± 0.743
0.892TyrAsp: 0.892 ± 0.778
1.19TyrGlu: 1.19 ± 0.282
2.38TyrPhe: 2.38 ± 0.804
3.272TyrGly: 3.272 ± 1.721
0.297TyrHis: 0.297 ± 0.155
2.38TyrIle: 2.38 ± 0.799
3.272TyrLys: 3.272 ± 0.844
4.759TyrLeu: 4.759 ± 0.842
0.0TyrMet: 0.0 ± 0.0
2.677TyrAsn: 2.677 ± 1.975
0.297TyrPro: 0.297 ± 0.155
0.892TyrGln: 0.892 ± 0.681
0.595TyrArg: 0.595 ± 0.317
3.569TyrSer: 3.569 ± 1.112
2.677TyrThr: 2.677 ± 0.378
1.785TyrVal: 1.785 ± 0.535
0.0TyrTrp: 0.0 ± 0.0
2.082TyrTyr: 2.082 ± 0.645
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3363 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski