Amino acid dipepetide frequency for Salarias fasciatus (Jewelled blenny) (Blennius fasciatus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.98AlaAla: 6.98 ± 0.024	1.361AlaCys: 1.361 ± 0.008	3.394AlaAsp: 3.394 ± 0.011	4.69AlaGlu: 4.69 ± 0.017	2.552AlaPhe: 2.552 ± 0.011	4.73AlaGly: 4.73 ± 0.026	1.535AlaHis: 1.535 ± 0.006	2.745AlaIle: 2.745 ± 0.01	3.283AlaLys: 3.283 ± 0.015	6.76AlaLeu: 6.76 ± 0.017	1.592AlaMet: 1.592 ± 0.007	2.113AlaAsn: 2.113 ± 0.01	3.645AlaPro: 3.645 ± 0.017	2.856AlaGln: 2.856 ± 0.011	3.354AlaArg: 3.354 ± 0.012	5.361AlaSer: 5.361 ± 0.017	3.304AlaThr: 3.304 ± 0.013	5.236AlaVal: 5.236 ± 0.016	0.684AlaTrp: 0.684 ± 0.005	1.608AlaTyr: 1.608 ± 0.007	0.0AlaXaa: 0.0 ± 0.0
Cys	1.223CysAla: 1.223 ± 0.007	0.673CysCys: 0.673 ± 0.006	1.148CysAsp: 1.148 ± 0.009	1.333CysGlu: 1.333 ± 0.011	1.009CysPhe: 1.009 ± 0.006	1.696CysGly: 1.696 ± 0.012	0.65CysHis: 0.65 ± 0.006	0.988CysIle: 0.988 ± 0.008	1.107CysLys: 1.107 ± 0.007	2.247CysLeu: 2.247 ± 0.011	0.465CysMet: 0.465 ± 0.004	0.778CysAsn: 0.778 ± 0.007	1.278CysPro: 1.278 ± 0.01	1.033CysGln: 1.033 ± 0.009	1.395CysArg: 1.395 ± 0.01	2.191CysSer: 2.191 ± 0.014	1.132CysThr: 1.132 ± 0.007	1.834CysVal: 1.834 ± 0.013	0.327CysTrp: 0.327 ± 0.003	0.622CysTyr: 0.622 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	3.202AspAla: 3.202 ± 0.012	1.19AspCys: 1.19 ± 0.008	3.068AspAsp: 3.068 ± 0.015	3.713AspGlu: 3.713 ± 0.014	2.308AspPhe: 2.308 ± 0.01	3.868AspGly: 3.868 ± 0.016	1.2AspHis: 1.2 ± 0.007	2.68AspIle: 2.68 ± 0.011	2.699AspLys: 2.699 ± 0.012	5.182AspLeu: 5.182 ± 0.014	1.271AspMet: 1.271 ± 0.006	1.898AspAsn: 1.898 ± 0.009	2.998AspPro: 2.998 ± 0.015	1.946AspGln: 1.946 ± 0.009	2.89AspArg: 2.89 ± 0.012	4.282AspSer: 4.282 ± 0.013	2.479AspThr: 2.479 ± 0.01	3.472AspVal: 3.472 ± 0.012	0.722AspTrp: 0.722 ± 0.005	1.604AspTyr: 1.604 ± 0.007	0.0AspXaa: 0.0 ± 0.0
Glu	4.846GluAla: 4.846 ± 0.02	1.257GluCys: 1.257 ± 0.009	4.334GluAsp: 4.334 ± 0.014	7.238GluGlu: 7.238 ± 0.036	2.068GluPhe: 2.068 ± 0.009	3.96GluGly: 3.96 ± 0.013	1.464GluHis: 1.464 ± 0.007	2.908GluIle: 2.908 ± 0.011	4.449GluLys: 4.449 ± 0.019	6.238GluLeu: 6.238 ± 0.022	1.681GluMet: 1.681 ± 0.008	2.699GluAsn: 2.699 ± 0.013	2.858GluPro: 2.858 ± 0.015	2.975GluGln: 2.975 ± 0.015	4.164GluArg: 4.164 ± 0.02	4.164GluSer: 4.164 ± 0.014	3.286GluThr: 3.286 ± 0.013	4.268GluVal: 4.268 ± 0.013	0.706GluTrp: 0.706 ± 0.005	1.652GluTyr: 1.652 ± 0.007	0.0GluXaa: 0.0 ± 0.0
Phe	2.072PheAla: 2.072 ± 0.008	1.004PheCys: 1.004 ± 0.006	1.927PheAsp: 1.927 ± 0.008	1.954PheGlu: 1.954 ± 0.008	1.915PhePhe: 1.915 ± 0.01	2.373PheGly: 2.373 ± 0.012	1.116PheHis: 1.116 ± 0.007	2.046PheIle: 2.046 ± 0.01	1.894PheLys: 1.894 ± 0.01	4.243PheLeu: 4.243 ± 0.015	0.864PheMet: 0.864 ± 0.005	1.554PheAsn: 1.554 ± 0.007	1.932PhePro: 1.932 ± 0.009	1.741PheGln: 1.741 ± 0.008	2.022PheArg: 2.022 ± 0.009	3.689PheSer: 3.689 ± 0.02	2.405PheThr: 2.405 ± 0.01	2.456PheVal: 2.456 ± 0.011	0.515PheTrp: 0.515 ± 0.005	1.312PheTyr: 1.312 ± 0.007	0.0PheXaa: 0.0 ± 0.0
Gly	4.274GlyAla: 4.274 ± 0.015	1.281GlyCys: 1.281 ± 0.009	3.287GlyAsp: 3.287 ± 0.014	4.107GlyGlu: 4.107 ± 0.015	2.69GlyPhe: 2.69 ± 0.021	5.561GlyGly: 5.561 ± 0.025	1.638GlyHis: 1.638 ± 0.008	2.62GlyIle: 2.62 ± 0.012	3.61GlyLys: 3.61 ± 0.011	5.638GlyLeu: 5.638 ± 0.017	1.442GlyMet: 1.442 ± 0.008	2.35GlyAsn: 2.35 ± 0.009	3.295GlyPro: 3.295 ± 0.024	2.661GlyGln: 2.661 ± 0.012	3.854GlyArg: 3.854 ± 0.015	5.627GlySer: 5.627 ± 0.026	3.338GlyThr: 3.338 ± 0.012	4.168GlyVal: 4.168 ± 0.014	0.8GlyTrp: 0.8 ± 0.005	1.873GlyTyr: 1.873 ± 0.01	0.0GlyXaa: 0.0 ± 0.0
His	1.406HisAla: 1.406 ± 0.007	0.8HisCys: 0.8 ± 0.006	1.012HisAsp: 1.012 ± 0.005	1.219HisGlu: 1.219 ± 0.006	1.133HisPhe: 1.133 ± 0.006	1.62HisGly: 1.62 ± 0.007	0.992HisHis: 0.992 ± 0.008	1.337HisIle: 1.337 ± 0.006	1.271HisLys: 1.271 ± 0.008	2.756HisLeu: 2.756 ± 0.011	0.686HisMet: 0.686 ± 0.005	1.014HisAsn: 1.014 ± 0.005	1.58HisPro: 1.58 ± 0.009	1.197HisGln: 1.197 ± 0.006	1.671HisArg: 1.671 ± 0.009	2.301HisSer: 2.301 ± 0.01	1.711HisThr: 1.711 ± 0.011	1.504HisVal: 1.504 ± 0.007	0.354HisTrp: 0.354 ± 0.003	0.856HisTyr: 0.856 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	2.579IleAla: 2.579 ± 0.009	1.063IleCys: 1.063 ± 0.006	2.184IleAsp: 2.184 ± 0.011	2.407IleGlu: 2.407 ± 0.01	1.934IlePhe: 1.934 ± 0.008	2.323IleGly: 2.323 ± 0.01	1.314IleHis: 1.314 ± 0.006	2.372IleIle: 2.372 ± 0.011	2.548IleLys: 2.548 ± 0.011	4.35IleLeu: 4.35 ± 0.014	1.087IleMet: 1.087 ± 0.006	1.991IleAsn: 1.991 ± 0.008	2.352IlePro: 2.352 ± 0.008	2.187IleGln: 2.187 ± 0.008	2.547IleArg: 2.547 ± 0.01	3.648IleSer: 3.648 ± 0.012	2.678IleThr: 2.678 ± 0.011	2.675IleVal: 2.675 ± 0.01	0.484IleTrp: 0.484 ± 0.005	1.461IleTyr: 1.461 ± 0.008	0.0IleXaa: 0.0 ± 0.0
Lys	3.663LysAla: 3.663 ± 0.014	1.019LysCys: 1.019 ± 0.007	3.173LysAsp: 3.173 ± 0.013	4.433LysGlu: 4.433 ± 0.019	1.73LysPhe: 1.73 ± 0.008	2.992LysGly: 2.992 ± 0.013	1.424LysHis: 1.424 ± 0.007	2.529LysIle: 2.529 ± 0.01	4.25LysLys: 4.25 ± 0.019	5.008LysLeu: 5.008 ± 0.014	1.41LysMet: 1.41 ± 0.007	2.233LysAsn: 2.233 ± 0.008	2.744LysPro: 2.744 ± 0.013	2.454LysGln: 2.454 ± 0.012	3.268LysArg: 3.268 ± 0.012	3.688LysSer: 3.688 ± 0.015	3.088LysThr: 3.088 ± 0.011	3.544LysVal: 3.544 ± 0.013	0.579LysTrp: 0.579 ± 0.005	1.561LysTyr: 1.561 ± 0.008	0.0LysXaa: 0.0 ± 0.0
Leu	6.185LeuAla: 6.185 ± 0.017	2.35LeuCys: 2.35 ± 0.012	5.112LeuAsp: 5.112 ± 0.013	6.412LeuGlu: 6.412 ± 0.027	3.726LeuPhe: 3.726 ± 0.014	5.213LeuGly: 5.213 ± 0.016	2.837LeuHis: 2.837 ± 0.012	3.986LeuIle: 3.986 ± 0.013	5.776LeuLys: 5.776 ± 0.019	10.537LeuLeu: 10.537 ± 0.028	2.182LeuMet: 2.182 ± 0.008	3.664LeuAsn: 3.664 ± 0.013	5.157LeuPro: 5.157 ± 0.015	5.543LeuGln: 5.543 ± 0.022	5.931LeuArg: 5.931 ± 0.018	8.368LeuSer: 8.368 ± 0.022	5.319LeuThr: 5.319 ± 0.013	5.678LeuVal: 5.678 ± 0.015	1.134LeuTrp: 1.134 ± 0.006	2.733LeuTyr: 2.733 ± 0.01	0.0LeuXaa: 0.0 ± 0.0
Met	1.837MetAla: 1.837 ± 0.008	0.501MetCys: 0.501 ± 0.003	1.398MetAsp: 1.398 ± 0.007	1.902MetGlu: 1.902 ± 0.008	0.908MetPhe: 0.908 ± 0.006	1.389MetGly: 1.389 ± 0.007	0.478MetHis: 0.478 ± 0.004	0.897MetIle: 0.897 ± 0.005	1.505MetLys: 1.505 ± 0.008	2.113MetLeu: 2.113 ± 0.01	0.674MetMet: 0.674 ± 0.004	0.919MetAsn: 0.919 ± 0.006	1.001MetPro: 1.001 ± 0.006	0.944MetGln: 0.944 ± 0.006	1.242MetArg: 1.242 ± 0.007	1.8MetSer: 1.8 ± 0.007	1.251MetThr: 1.251 ± 0.006	1.545MetVal: 1.545 ± 0.007	0.273MetTrp: 0.273 ± 0.003	0.654MetTyr: 0.654 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.183AsnAla: 2.183 ± 0.009	0.871AsnCys: 0.871 ± 0.007	1.693AsnAsp: 1.693 ± 0.009	2.016AsnGlu: 2.016 ± 0.01	1.476AsnPhe: 1.476 ± 0.007	2.663AsnGly: 2.663 ± 0.014	0.976AsnHis: 0.976 ± 0.006	2.125AsnIle: 2.125 ± 0.01	2.11AsnLys: 2.11 ± 0.008	3.623AsnLeu: 3.623 ± 0.01	1.009AsnMet: 1.009 ± 0.005	1.696AsnAsn: 1.696 ± 0.008	2.259AsnPro: 2.259 ± 0.011	1.694AsnGln: 1.694 ± 0.008	1.974AsnArg: 1.974 ± 0.009	2.956AsnSer: 2.956 ± 0.013	2.1AsnThr: 2.1 ± 0.008	2.34AsnVal: 2.34 ± 0.009	0.455AsnTrp: 0.455 ± 0.004	1.165AsnTyr: 1.165 ± 0.006	0.0AsnXaa: 0.0 ± 0.0
Pro	4.362ProAla: 4.362 ± 0.018	1.049ProCys: 1.049 ± 0.009	3.003ProAsp: 3.003 ± 0.012	3.776ProGlu: 3.776 ± 0.014	1.817ProPhe: 1.817 ± 0.008	4.253ProGly: 4.253 ± 0.031	1.483ProHis: 1.483 ± 0.007	1.766ProIle: 1.766 ± 0.008	2.32ProLys: 2.32 ± 0.01	4.837ProLeu: 4.837 ± 0.015	0.97ProMet: 0.97 ± 0.007	1.833ProAsn: 1.833 ± 0.009	5.379ProPro: 5.379 ± 0.034	2.51ProGln: 2.51 ± 0.013	2.78ProArg: 2.78 ± 0.012	5.103ProSer: 5.103 ± 0.019	2.758ProThr: 2.758 ± 0.013	3.666ProVal: 3.666 ± 0.014	0.571ProTrp: 0.571 ± 0.005	1.427ProTyr: 1.427 ± 0.008	0.0ProXaa: 0.0 ± 0.0
Gln	3.135GlnAla: 3.135 ± 0.014	0.97GlnCys: 0.97 ± 0.008	2.343GlnAsp: 2.343 ± 0.01	3.308GlnGlu: 3.308 ± 0.014	1.432GlnPhe: 1.432 ± 0.008	2.616GlnGly: 2.616 ± 0.012	1.282GlnHis: 1.282 ± 0.007	1.997GlnIle: 1.997 ± 0.008	2.507GlnLys: 2.507 ± 0.012	4.505GlnLeu: 4.505 ± 0.016	1.12GlnMet: 1.12 ± 0.006	1.673GlnAsn: 1.673 ± 0.009	2.356GlnPro: 2.356 ± 0.011	3.152GlnGln: 3.152 ± 0.024	3.016GlnArg: 3.016 ± 0.013	3.221GlnSer: 3.221 ± 0.013	2.491GlnThr: 2.491 ± 0.012	2.828GlnVal: 2.828 ± 0.01	0.574GlnTrp: 0.574 ± 0.004	1.276GlnTyr: 1.276 ± 0.007	0.0GlnXaa: 0.0 ± 0.0
Arg	3.62ArgAla: 3.62 ± 0.013	1.33ArgCys: 1.33 ± 0.009	3.071ArgAsp: 3.071 ± 0.012	3.887ArgGlu: 3.887 ± 0.015	2.156ArgPhe: 2.156 ± 0.01	3.557ArgGly: 3.557 ± 0.014	1.588ArgHis: 1.588 ± 0.008	2.489ArgIle: 2.489 ± 0.01	3.443ArgLys: 3.443 ± 0.011	5.729ArgLeu: 5.729 ± 0.02	1.296ArgMet: 1.296 ± 0.007	2.137ArgAsn: 2.137 ± 0.008	3.069ArgPro: 3.069 ± 0.013	2.629ArgGln: 2.629 ± 0.01	4.541ArgArg: 4.541 ± 0.015	4.522ArgSer: 4.522 ± 0.017	2.974ArgThr: 2.974 ± 0.011	3.476ArgVal: 3.476 ± 0.011	0.734ArgTrp: 0.734 ± 0.005	1.627ArgTyr: 1.627 ± 0.007	0.0ArgXaa: 0.0 ± 0.0
Ser	5.706SerAla: 5.706 ± 0.022	2.062SerCys: 2.062 ± 0.013	4.248SerAsp: 4.248 ± 0.013	4.836SerGlu: 4.836 ± 0.022	3.254SerPhe: 3.254 ± 0.011	5.629SerGly: 5.629 ± 0.021	2.118SerHis: 2.118 ± 0.01	3.212SerIle: 3.212 ± 0.011	3.696SerLys: 3.696 ± 0.014	8.242SerLeu: 8.242 ± 0.022	1.717SerMet: 1.717 ± 0.006	2.813SerAsn: 2.813 ± 0.011	5.411SerPro: 5.411 ± 0.021	3.552SerGln: 3.552 ± 0.013	4.602SerArg: 4.602 ± 0.017	9.463SerSer: 9.463 ± 0.04	4.292SerThr: 4.292 ± 0.022	5.45SerVal: 5.45 ± 0.017	1.026SerTrp: 1.026 ± 0.01	2.119SerTyr: 2.119 ± 0.009	0.0SerXaa: 0.0 ± 0.0
Thr	4.025ThrAla: 4.025 ± 0.012	1.387ThrCys: 1.387 ± 0.011	2.848ThrAsp: 2.848 ± 0.012	3.497ThrGlu: 3.497 ± 0.013	2.21ThrPhe: 2.21 ± 0.01	3.669ThrGly: 3.669 ± 0.016	1.558ThrHis: 1.558 ± 0.011	2.32ThrIle: 2.32 ± 0.009	2.469ThrLys: 2.469 ± 0.009	5.349ThrLeu: 5.349 ± 0.014	1.164ThrMet: 1.164 ± 0.007	1.808ThrAsn: 1.808 ± 0.009	3.369ThrPro: 3.369 ± 0.014	2.19ThrGln: 2.19 ± 0.01	2.502ThrArg: 2.502 ± 0.011	4.291ThrSer: 4.291 ± 0.016	2.968ThrThr: 2.968 ± 0.041	4.135ThrVal: 4.135 ± 0.014	0.66ThrTrp: 0.66 ± 0.005	1.438ThrTyr: 1.438 ± 0.008	0.0ThrXaa: 0.0 ± 0.0
Val	4.276ValAla: 4.276 ± 0.012	1.975ValCys: 1.975 ± 0.013	3.318ValAsp: 3.318 ± 0.011	4.059ValGlu: 4.059 ± 0.015	2.909ValPhe: 2.909 ± 0.011	3.599ValGly: 3.599 ± 0.012	1.684ValHis: 1.684 ± 0.007	3.06ValIle: 3.06 ± 0.011	3.615ValLys: 3.615 ± 0.013	6.514ValLeu: 6.514 ± 0.017	1.543ValMet: 1.543 ± 0.007	2.486ValAsn: 2.486 ± 0.01	3.24ValPro: 3.24 ± 0.012	2.783ValGln: 2.783 ± 0.011	3.589ValArg: 3.589 ± 0.012	5.402ValSer: 5.402 ± 0.015	3.902ValThr: 3.902 ± 0.014	4.562ValVal: 4.562 ± 0.014	0.831ValTrp: 0.831 ± 0.006	1.898ValTyr: 1.898 ± 0.009	0.0ValXaa: 0.0 ± 0.0
Trp	0.708TrpAla: 0.708 ± 0.005	0.259TrpCys: 0.259 ± 0.003	0.667TrpAsp: 0.667 ± 0.005	0.777TrpGlu: 0.777 ± 0.006	0.495TrpPhe: 0.495 ± 0.004	0.664TrpGly: 0.664 ± 0.006	0.268TrpHis: 0.268 ± 0.003	0.611TrpIle: 0.611 ± 0.005	0.751TrpLys: 0.751 ± 0.005	1.197TrpLeu: 1.197 ± 0.008	0.365TrpMet: 0.365 ± 0.003	0.53TrpAsn: 0.53 ± 0.005	0.439TrpPro: 0.439 ± 0.004	0.494TrpGln: 0.494 ± 0.004	0.78TrpArg: 0.78 ± 0.006	1.003TrpSer: 1.003 ± 0.007	0.744TrpThr: 0.744 ± 0.006	0.72TrpVal: 0.72 ± 0.005	0.215TrpTrp: 0.215 ± 0.004	0.359TrpTyr: 0.359 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.499TyrAla: 1.499 ± 0.007	0.726TyrCys: 0.726 ± 0.005	1.444TyrAsp: 1.444 ± 0.008	1.653TyrGlu: 1.653 ± 0.008	1.312TyrPhe: 1.312 ± 0.007	1.739TyrGly: 1.739 ± 0.009	0.811TyrHis: 0.811 ± 0.006	1.496TyrIle: 1.496 ± 0.007	1.49TyrLys: 1.49 ± 0.007	2.775TyrLeu: 2.775 ± 0.011	0.692TyrMet: 0.692 ± 0.005	1.196TyrAsn: 1.196 ± 0.006	1.301TyrPro: 1.301 ± 0.007	1.26TyrGln: 1.26 ± 0.007	1.754TyrArg: 1.754 ± 0.008	2.368TyrSer: 2.368 ± 0.01	1.638TyrThr: 1.638 ± 0.007	1.688TyrVal: 1.688 ± 0.007	0.401TyrTrp: 0.401 ± 0.004	1.012TyrTyr: 1.012 ± 0.006	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.004XaaXaa: 0.004 ± 0.002

Statistics based on 55738 proteins (33321467 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---