Amino acid dipepetide frequency for Kiritimatiella glycovorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.002AlaAla: 13.002 ± 0.201	1.367AlaCys: 1.367 ± 0.044	5.814AlaAsp: 5.814 ± 0.082	7.89AlaGlu: 7.89 ± 0.101	3.705AlaPhe: 3.705 ± 0.082	9.88AlaGly: 9.88 ± 0.142	2.06AlaHis: 2.06 ± 0.052	3.823AlaIle: 3.823 ± 0.075	2.421AlaLys: 2.421 ± 0.06	10.674AlaLeu: 10.674 ± 0.148	2.525AlaMet: 2.525 ± 0.05	1.983AlaAsn: 1.983 ± 0.053	4.569AlaPro: 4.569 ± 0.075	2.693AlaGln: 2.693 ± 0.055	8.241AlaArg: 8.241 ± 0.126	4.725AlaSer: 4.725 ± 0.08	3.657AlaThr: 3.657 ± 0.067	8.29AlaVal: 8.29 ± 0.119	1.544AlaTrp: 1.544 ± 0.045	2.353AlaTyr: 2.353 ± 0.061	0.0AlaXaa: 0.0 ± 0.0
Cys	1.343CysAla: 1.343 ± 0.037	0.192CysCys: 0.192 ± 0.014	0.77CysAsp: 0.77 ± 0.033	0.854CysGlu: 0.854 ± 0.033	0.499CysPhe: 0.499 ± 0.024	1.48CysGly: 1.48 ± 0.045	0.314CysHis: 0.314 ± 0.022	0.497CysIle: 0.497 ± 0.023	0.201CysLys: 0.201 ± 0.016	0.978CysLeu: 0.978 ± 0.036	0.239CysMet: 0.239 ± 0.014	0.308CysAsn: 0.308 ± 0.02	0.758CysPro: 0.758 ± 0.042	0.2CysGln: 0.2 ± 0.015	1.274CysArg: 1.274 ± 0.041	0.654CysSer: 0.654 ± 0.026	0.653CysThr: 0.653 ± 0.03	0.815CysVal: 0.815 ± 0.028	0.169CysTrp: 0.169 ± 0.014	0.352CysTyr: 0.352 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	6.153AspAla: 6.153 ± 0.097	0.653AspCys: 0.653 ± 0.027	3.311AspAsp: 3.311 ± 0.071	4.538AspGlu: 4.538 ± 0.085	2.453AspPhe: 2.453 ± 0.051	5.267AspGly: 5.267 ± 0.093	1.411AspHis: 1.411 ± 0.044	2.591AspIle: 2.591 ± 0.057	1.34AspLys: 1.34 ± 0.046	6.199AspLeu: 6.199 ± 0.092	1.24AspMet: 1.24 ± 0.037	1.199AspAsn: 1.199 ± 0.04	4.181AspPro: 4.181 ± 0.074	1.489AspGln: 1.489 ± 0.046	5.977AspArg: 5.977 ± 0.089	2.359AspSer: 2.359 ± 0.059	2.898AspThr: 2.898 ± 0.058	3.87AspVal: 3.87 ± 0.077	1.081AspTrp: 1.081 ± 0.036	1.85AspTyr: 1.85 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	7.932GluAla: 7.932 ± 0.124	0.702GluCys: 0.702 ± 0.03	4.358GluAsp: 4.358 ± 0.075	5.656GluGlu: 5.656 ± 0.104	2.128GluPhe: 2.128 ± 0.045	5.746GluGly: 5.746 ± 0.084	1.924GluHis: 1.924 ± 0.054	3.687GluIle: 3.687 ± 0.067	3.002GluLys: 3.002 ± 0.077	6.893GluLeu: 6.893 ± 0.104	1.93GluMet: 1.93 ± 0.049	2.017GluAsn: 2.017 ± 0.059	3.425GluPro: 3.425 ± 0.068	2.856GluGln: 2.856 ± 0.067	6.687GluArg: 6.687 ± 0.106	3.743GluSer: 3.743 ± 0.072	4.03GluThr: 4.03 ± 0.066	4.848GluVal: 4.848 ± 0.077	1.076GluTrp: 1.076 ± 0.036	1.998GluTyr: 1.998 ± 0.053	0.0GluXaa: 0.0 ± 0.0
Phe	3.616PheAla: 3.616 ± 0.072	0.537PheCys: 0.537 ± 0.026	2.705PheAsp: 2.705 ± 0.063	2.896PheGlu: 2.896 ± 0.06	1.678PhePhe: 1.678 ± 0.054	3.217PheGly: 3.217 ± 0.068	0.887PheHis: 0.887 ± 0.033	1.679PheIle: 1.679 ± 0.052	1.008PheLys: 1.008 ± 0.041	3.397PheLeu: 3.397 ± 0.068	0.866PheMet: 0.866 ± 0.032	1.161PheAsn: 1.161 ± 0.037	1.811PhePro: 1.811 ± 0.048	0.892PheGln: 0.892 ± 0.034	3.274PheArg: 3.274 ± 0.069	2.273PheSer: 2.273 ± 0.045	2.078PheThr: 2.078 ± 0.053	2.455PheVal: 2.455 ± 0.054	0.55PheTrp: 0.55 ± 0.027	1.163PheTyr: 1.163 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	7.928GlyAla: 7.928 ± 0.111	1.225GlyCys: 1.225 ± 0.04	4.869GlyAsp: 4.869 ± 0.086	6.076GlyGlu: 6.076 ± 0.092	3.35GlyPhe: 3.35 ± 0.061	7.65GlyGly: 7.65 ± 0.105	2.01GlyHis: 2.01 ± 0.048	4.257GlyIle: 4.257 ± 0.075	2.964GlyLys: 2.964 ± 0.063	7.777GlyLeu: 7.777 ± 0.09	2.394GlyMet: 2.394 ± 0.06	2.143GlyAsn: 2.143 ± 0.061	3.518GlyPro: 3.518 ± 0.07	2.068GlyGln: 2.068 ± 0.044	7.573GlyArg: 7.573 ± 0.113	4.407GlySer: 4.407 ± 0.077	4.738GlyThr: 4.738 ± 0.098	6.089GlyVal: 6.089 ± 0.08	1.492GlyTrp: 1.492 ± 0.047	2.608GlyTyr: 2.608 ± 0.065	0.0GlyXaa: 0.0 ± 0.0
His	2.29HisAla: 2.29 ± 0.053	0.335HisCys: 0.335 ± 0.02	1.239HisAsp: 1.239 ± 0.038	1.577HisGlu: 1.577 ± 0.044	1.033HisPhe: 1.033 ± 0.036	2.037HisGly: 2.037 ± 0.056	0.671HisHis: 0.671 ± 0.027	0.988HisIle: 0.988 ± 0.029	0.598HisLys: 0.598 ± 0.025	2.419HisLeu: 2.419 ± 0.05	0.431HisMet: 0.431 ± 0.024	0.586HisAsn: 0.586 ± 0.031	1.721HisPro: 1.721 ± 0.045	0.591HisGln: 0.591 ± 0.024	1.978HisArg: 1.978 ± 0.05	1.038HisSer: 1.038 ± 0.036	1.189HisThr: 1.189 ± 0.041	1.543HisVal: 1.543 ± 0.044	0.408HisTrp: 0.408 ± 0.025	0.809HisTyr: 0.809 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	4.577IleAla: 4.577 ± 0.075	0.609IleCys: 0.609 ± 0.029	3.308IleAsp: 3.308 ± 0.062	3.884IleGlu: 3.884 ± 0.077	1.666IlePhe: 1.666 ± 0.045	3.955IleGly: 3.955 ± 0.076	1.127IleHis: 1.127 ± 0.034	1.833IleIle: 1.833 ± 0.062	1.182IleLys: 1.182 ± 0.039	4.035IleLeu: 4.035 ± 0.072	0.968IleMet: 0.968 ± 0.034	1.291IleAsn: 1.291 ± 0.041	2.644IlePro: 2.644 ± 0.063	1.133IleGln: 1.133 ± 0.039	4.266IleArg: 4.266 ± 0.073	2.39IleSer: 2.39 ± 0.053	2.419IleThr: 2.419 ± 0.055	3.062IleVal: 3.062 ± 0.061	0.453IleTrp: 0.453 ± 0.026	1.253IleTyr: 1.253 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	2.968LysAla: 2.968 ± 0.075	0.26LysCys: 0.26 ± 0.02	1.691LysAsp: 1.691 ± 0.053	1.967LysGlu: 1.967 ± 0.058	0.769LysPhe: 0.769 ± 0.032	2.321LysGly: 2.321 ± 0.052	0.68LysHis: 0.68 ± 0.03	1.603LysIle: 1.603 ± 0.048	1.794LysLys: 1.794 ± 0.073	2.828LysLeu: 2.828 ± 0.062	0.758LysMet: 0.758 ± 0.031	0.958LysAsn: 0.958 ± 0.038	1.756LysPro: 1.756 ± 0.05	1.118LysGln: 1.118 ± 0.044	2.651LysArg: 2.651 ± 0.061	1.699LysSer: 1.699 ± 0.046	1.957LysThr: 1.957 ± 0.05	2.053LysVal: 2.053 ± 0.046	0.474LysTrp: 0.474 ± 0.027	0.809LysTyr: 0.809 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	9.727LeuAla: 9.727 ± 0.137	1.327LeuCys: 1.327 ± 0.047	6.153LeuAsp: 6.153 ± 0.099	7.178LeuGlu: 7.178 ± 0.109	3.763LeuPhe: 3.763 ± 0.077	7.169LeuGly: 7.169 ± 0.101	2.228LeuHis: 2.228 ± 0.056	4.552LeuIle: 4.552 ± 0.079	3.499LeuLys: 3.499 ± 0.068	9.242LeuLeu: 9.242 ± 0.15	2.236LeuMet: 2.236 ± 0.051	2.798LeuAsn: 2.798 ± 0.059	4.969LeuPro: 4.969 ± 0.08	2.677LeuGln: 2.677 ± 0.058	8.591LeuArg: 8.591 ± 0.134	5.28LeuSer: 5.28 ± 0.089	4.817LeuThr: 4.817 ± 0.086	5.984LeuVal: 5.984 ± 0.098	1.27LeuTrp: 1.27 ± 0.04	2.748LeuTyr: 2.748 ± 0.07	0.0LeuXaa: 0.0 ± 0.0
Met	2.366MetAla: 2.366 ± 0.061	0.172MetCys: 0.172 ± 0.015	1.477MetAsp: 1.477 ± 0.043	1.604MetGlu: 1.604 ± 0.044	0.693MetPhe: 0.693 ± 0.029	1.694MetGly: 1.694 ± 0.048	0.548MetHis: 0.548 ± 0.024	1.386MetIle: 1.386 ± 0.038	1.418MetLys: 1.418 ± 0.034	2.344MetLeu: 2.344 ± 0.058	0.668MetMet: 0.668 ± 0.032	1.018MetAsn: 1.018 ± 0.034	1.271MetPro: 1.271 ± 0.035	0.679MetGln: 0.679 ± 0.029	2.0MetArg: 2.0 ± 0.055	1.319MetSer: 1.319 ± 0.037	1.458MetThr: 1.458 ± 0.04	1.353MetVal: 1.353 ± 0.041	0.195MetTrp: 0.195 ± 0.017	0.451MetTyr: 0.451 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.557AsnAla: 2.557 ± 0.055	0.324AsnCys: 0.324 ± 0.024	1.446AsnAsp: 1.446 ± 0.046	1.535AsnGlu: 1.535 ± 0.047	0.909AsnPhe: 0.909 ± 0.035	2.33AsnGly: 2.33 ± 0.056	0.687AsnHis: 0.687 ± 0.029	1.37AsnIle: 1.37 ± 0.053	0.666AsnLys: 0.666 ± 0.031	2.669AsnLeu: 2.669 ± 0.056	0.588AsnMet: 0.588 ± 0.027	0.715AsnAsn: 0.715 ± 0.032	1.899AsnPro: 1.899 ± 0.047	0.672AsnGln: 0.672 ± 0.026	2.43AsnArg: 2.43 ± 0.053	1.128AsnSer: 1.128 ± 0.04	1.446AsnThr: 1.446 ± 0.045	1.745AsnVal: 1.745 ± 0.048	0.465AsnTrp: 0.465 ± 0.028	0.783AsnTyr: 0.783 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	5.564ProAla: 5.564 ± 0.081	0.587ProCys: 0.587 ± 0.03	4.052ProAsp: 4.052 ± 0.076	5.441ProGlu: 5.441 ± 0.091	2.092ProPhe: 2.092 ± 0.05	5.098ProGly: 5.098 ± 0.089	1.284ProHis: 1.284 ± 0.04	1.489ProIle: 1.489 ± 0.044	1.259ProLys: 1.259 ± 0.044	4.374ProLeu: 4.374 ± 0.084	1.19ProMet: 1.19 ± 0.038	1.177ProAsn: 1.177 ± 0.037	2.882ProPro: 2.882 ± 0.068	1.357ProGln: 1.357 ± 0.042	3.656ProArg: 3.656 ± 0.078	2.695ProSer: 2.695 ± 0.065	1.78ProThr: 1.78 ± 0.054	4.412ProVal: 4.412 ± 0.082	0.84ProTrp: 0.84 ± 0.034	1.421ProTyr: 1.421 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.654GlnAla: 2.654 ± 0.064	0.363GlnCys: 0.363 ± 0.023	1.295GlnAsp: 1.295 ± 0.044	1.731GlnGlu: 1.731 ± 0.054	1.027GlnPhe: 1.027 ± 0.037	2.063GlnGly: 2.063 ± 0.047	0.624GlnHis: 0.624 ± 0.027	1.411GlnIle: 1.411 ± 0.042	1.085GlnLys: 1.085 ± 0.038	2.389GlnLeu: 2.389 ± 0.053	0.652GlnMet: 0.652 ± 0.032	0.839GlnAsn: 0.839 ± 0.032	1.32GlnPro: 1.32 ± 0.042	1.054GlnGln: 1.054 ± 0.045	2.397GlnArg: 2.397 ± 0.059	1.48GlnSer: 1.48 ± 0.046	1.484GlnThr: 1.484 ± 0.049	1.772GlnVal: 1.772 ± 0.045	0.483GlnTrp: 0.483 ± 0.025	0.846GlnTyr: 0.846 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	8.312ArgAla: 8.312 ± 0.118	1.059ArgCys: 1.059 ± 0.038	5.083ArgAsp: 5.083 ± 0.072	7.537ArgGlu: 7.537 ± 0.125	3.6ArgPhe: 3.6 ± 0.067	6.382ArgGly: 6.382 ± 0.108	2.086ArgHis: 2.086 ± 0.06	4.948ArgIle: 4.948 ± 0.087	3.042ArgLys: 3.042 ± 0.061	8.205ArgLeu: 8.205 ± 0.109	2.343ArgMet: 2.343 ± 0.054	2.344ArgAsn: 2.344 ± 0.053	4.208ArgPro: 4.208 ± 0.081	2.268ArgGln: 2.268 ± 0.056	8.684ArgArg: 8.684 ± 0.137	4.172ArgSer: 4.172 ± 0.077	4.28ArgThr: 4.28 ± 0.075	5.97ArgVal: 5.97 ± 0.088	1.377ArgTrp: 1.377 ± 0.041	2.637ArgTyr: 2.637 ± 0.064	0.0ArgXaa: 0.0 ± 0.0
Ser	5.11SerAla: 5.11 ± 0.071	0.643SerCys: 0.643 ± 0.03	2.841SerAsp: 2.841 ± 0.06	3.292SerGlu: 3.292 ± 0.063	2.123SerPhe: 2.123 ± 0.06	5.543SerGly: 5.543 ± 0.095	1.046SerHis: 1.046 ± 0.036	2.359SerIle: 2.359 ± 0.055	1.272SerLys: 1.272 ± 0.039	4.703SerLeu: 4.703 ± 0.079	1.331SerMet: 1.331 ± 0.04	1.266SerAsn: 1.266 ± 0.048	2.725SerPro: 2.725 ± 0.058	1.142SerGln: 1.142 ± 0.043	4.228SerArg: 4.228 ± 0.074	2.823SerSer: 2.823 ± 0.066	2.451SerThr: 2.451 ± 0.063	3.57SerVal: 3.57 ± 0.071	0.765SerTrp: 0.765 ± 0.032	1.347SerTyr: 1.347 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	5.147ThrAla: 5.147 ± 0.092	0.589ThrCys: 0.589 ± 0.031	2.756ThrAsp: 2.756 ± 0.059	3.032ThrGlu: 3.032 ± 0.06	2.03ThrPhe: 2.03 ± 0.051	5.217ThrGly: 5.217 ± 0.092	1.053ThrHis: 1.053 ± 0.034	2.224ThrIle: 2.224 ± 0.056	1.094ThrLys: 1.094 ± 0.041	5.356ThrLeu: 5.356 ± 0.089	1.047ThrMet: 1.047 ± 0.035	1.415ThrAsn: 1.415 ± 0.064	3.213ThrPro: 3.213 ± 0.074	1.114ThrGln: 1.114 ± 0.036	3.729ThrArg: 3.729 ± 0.064	2.272ThrSer: 2.272 ± 0.064	2.3ThrThr: 2.3 ± 0.066	4.08ThrVal: 4.08 ± 0.068	0.698ThrTrp: 0.698 ± 0.033	1.283ThrTyr: 1.283 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	6.066ValAla: 6.066 ± 0.095	1.069ValCys: 1.069 ± 0.035	4.16ValAsp: 4.16 ± 0.071	5.114ValGlu: 5.114 ± 0.084	2.883ValPhe: 2.883 ± 0.068	4.476ValGly: 4.476 ± 0.075	1.692ValHis: 1.692 ± 0.05	3.358ValIle: 3.358 ± 0.07	2.05ValLys: 2.05 ± 0.06	7.543ValLeu: 7.543 ± 0.123	1.663ValMet: 1.663 ± 0.048	1.866ValAsn: 1.866 ± 0.05	3.715ValPro: 3.715 ± 0.069	1.869ValGln: 1.869 ± 0.045	6.616ValArg: 6.616 ± 0.111	3.849ValSer: 3.849 ± 0.074	3.74ValThr: 3.74 ± 0.068	4.897ValVal: 4.897 ± 0.091	0.888ValTrp: 0.888 ± 0.033	1.989ValTyr: 1.989 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.113TrpAla: 1.113 ± 0.038	0.177TrpCys: 0.177 ± 0.015	0.849TrpAsp: 0.849 ± 0.033	0.863TrpGlu: 0.863 ± 0.036	0.597TrpPhe: 0.597 ± 0.03	1.011TrpGly: 1.011 ± 0.037	0.406TrpHis: 0.406 ± 0.025	0.89TrpIle: 0.89 ± 0.031	0.634TrpLys: 0.634 ± 0.028	1.424TrpLeu: 1.424 ± 0.043	0.54TrpMet: 0.54 ± 0.027	0.576TrpAsn: 0.576 ± 0.026	0.664TrpPro: 0.664 ± 0.029	0.466TrpGln: 0.466 ± 0.026	1.336TrpArg: 1.336 ± 0.039	0.906TrpSer: 0.906 ± 0.036	0.934TrpThr: 0.934 ± 0.035	0.881TrpVal: 0.881 ± 0.031	0.285TrpTrp: 0.285 ± 0.02	0.404TrpTyr: 0.404 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.79TyrAla: 2.79 ± 0.059	0.363TyrCys: 0.363 ± 0.018	1.88TyrAsp: 1.88 ± 0.052	1.972TyrGlu: 1.972 ± 0.058	1.143TyrPhe: 1.143 ± 0.037	2.601TyrGly: 2.601 ± 0.062	0.744TyrHis: 0.744 ± 0.034	1.11TyrIle: 1.11 ± 0.037	0.585TyrLys: 0.585 ± 0.026	2.759TyrLeu: 2.759 ± 0.054	0.504TyrMet: 0.504 ± 0.025	0.703TyrAsn: 0.703 ± 0.03	1.403TyrPro: 1.403 ± 0.045	0.632TyrGln: 0.632 ± 0.027	2.951TyrArg: 2.951 ± 0.059	1.365TyrSer: 1.365 ± 0.048	1.341TyrThr: 1.341 ± 0.041	1.814TyrVal: 1.814 ± 0.047	0.445TyrTrp: 0.445 ± 0.026	0.97TyrTyr: 0.97 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2373 proteins (860530 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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