Amino acid dipepetide frequency for Ferrimonas marina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.481AlaAla: 10.481 ± 0.113	1.124AlaCys: 1.124 ± 0.029	5.68AlaAsp: 5.68 ± 0.077	7.262AlaGlu: 7.262 ± 0.077	3.555AlaPhe: 3.555 ± 0.051	7.554AlaGly: 7.554 ± 0.08	1.946AlaHis: 1.946 ± 0.039	5.233AlaIle: 5.233 ± 0.063	4.09AlaLys: 4.09 ± 0.067	13.475AlaLeu: 13.475 ± 0.115	3.233AlaMet: 3.233 ± 0.049	3.379AlaAsn: 3.379 ± 0.054	4.343AlaPro: 4.343 ± 0.071	5.88AlaGln: 5.88 ± 0.078	5.584AlaArg: 5.584 ± 0.063	5.911AlaSer: 5.911 ± 0.067	4.752AlaThr: 4.752 ± 0.057	6.956AlaVal: 6.956 ± 0.076	1.423AlaTrp: 1.423 ± 0.041	2.452AlaTyr: 2.452 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.948CysAla: 0.948 ± 0.03	0.159CysCys: 0.159 ± 0.012	0.65CysAsp: 0.65 ± 0.02	0.563CysGlu: 0.563 ± 0.021	0.351CysPhe: 0.351 ± 0.017	0.983CysGly: 0.983 ± 0.03	0.507CysHis: 0.507 ± 0.03	0.416CysIle: 0.416 ± 0.018	0.261CysLys: 0.261 ± 0.014	1.085CysLeu: 1.085 ± 0.027	0.208CysMet: 0.208 ± 0.011	0.311CysAsn: 0.311 ± 0.015	0.614CysPro: 0.614 ± 0.024	0.648CysGln: 0.648 ± 0.023	0.647CysArg: 0.647 ± 0.023	0.644CysSer: 0.644 ± 0.022	0.478CysThr: 0.478 ± 0.018	0.579CysVal: 0.579 ± 0.02	0.147CysTrp: 0.147 ± 0.01	0.296CysTyr: 0.296 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.404AspAla: 5.404 ± 0.07	0.576AspCys: 0.576 ± 0.021	3.025AspAsp: 3.025 ± 0.052	3.451AspGlu: 3.451 ± 0.055	2.103AspPhe: 2.103 ± 0.041	4.811AspGly: 4.811 ± 0.075	1.305AspHis: 1.305 ± 0.034	2.48AspIle: 2.48 ± 0.045	2.289AspLys: 2.289 ± 0.044	5.81AspLeu: 5.81 ± 0.074	1.227AspMet: 1.227 ± 0.027	2.159AspAsn: 2.159 ± 0.039	3.168AspPro: 3.168 ± 0.06	2.632AspGln: 2.632 ± 0.049	3.226AspArg: 3.226 ± 0.057	3.36AspSer: 3.36 ± 0.052	2.676AspThr: 2.676 ± 0.049	3.145AspVal: 3.145 ± 0.053	1.02AspTrp: 1.02 ± 0.029	1.877AspTyr: 1.877 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	6.801GluAla: 6.801 ± 0.081	0.461GluCys: 0.461 ± 0.02	2.712GluAsp: 2.712 ± 0.048	3.438GluGlu: 3.438 ± 0.068	2.033GluPhe: 2.033 ± 0.049	4.395GluGly: 4.395 ± 0.059	1.647GluHis: 1.647 ± 0.032	2.78GluIle: 2.78 ± 0.043	1.971GluLys: 1.971 ± 0.044	7.344GluLeu: 7.344 ± 0.088	1.663GluMet: 1.663 ± 0.034	1.57GluAsn: 1.57 ± 0.034	2.778GluPro: 2.778 ± 0.05	5.129GluGln: 5.129 ± 0.067	4.372GluArg: 4.372 ± 0.063	3.196GluSer: 3.196 ± 0.054	2.62GluThr: 2.62 ± 0.049	4.486GluVal: 4.486 ± 0.066	0.722GluTrp: 0.722 ± 0.026	1.437GluTyr: 1.437 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.923PheAla: 3.923 ± 0.059	0.423PheCys: 0.423 ± 0.02	2.716PheAsp: 2.716 ± 0.044	2.384PheGlu: 2.384 ± 0.04	1.293PhePhe: 1.293 ± 0.033	3.102PheGly: 3.102 ± 0.051	0.779PheHis: 0.779 ± 0.024	1.675PheIle: 1.675 ± 0.039	1.103PheLys: 1.103 ± 0.028	3.116PheLeu: 3.116 ± 0.046	0.82PheMet: 0.82 ± 0.023	1.42PheAsn: 1.42 ± 0.033	1.324PhePro: 1.324 ± 0.035	1.27PheGln: 1.27 ± 0.029	1.719PheArg: 1.719 ± 0.034	2.486PheSer: 2.486 ± 0.044	1.92PheThr: 1.92 ± 0.041	2.554PheVal: 2.554 ± 0.045	0.523PheTrp: 0.523 ± 0.021	1.135PheTyr: 1.135 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	6.663GlyAla: 6.663 ± 0.086	1.033GlyCys: 1.033 ± 0.028	4.325GlyAsp: 4.325 ± 0.071	5.019GlyGlu: 5.019 ± 0.073	3.27GlyPhe: 3.27 ± 0.049	5.611GlyGly: 5.611 ± 0.088	1.934GlyHis: 1.934 ± 0.042	4.03GlyIle: 4.03 ± 0.053	3.133GlyLys: 3.133 ± 0.06	8.549GlyLeu: 8.549 ± 0.088	2.315GlyMet: 2.315 ± 0.043	2.483GlyAsn: 2.483 ± 0.05	2.625GlyPro: 2.625 ± 0.046	4.321GlyGln: 4.321 ± 0.06	4.332GlyArg: 4.332 ± 0.059	4.45GlySer: 4.45 ± 0.067	3.681GlyThr: 3.681 ± 0.054	5.598GlyVal: 5.598 ± 0.068	1.296GlyTrp: 1.296 ± 0.034	2.633GlyTyr: 2.633 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.91HisAla: 1.91 ± 0.044	0.421HisCys: 0.421 ± 0.02	1.104HisAsp: 1.104 ± 0.03	0.97HisGlu: 0.97 ± 0.031	1.041HisPhe: 1.041 ± 0.028	1.986HisGly: 1.986 ± 0.038	0.87HisHis: 0.87 ± 0.031	0.976HisIle: 0.976 ± 0.026	0.785HisLys: 0.785 ± 0.024	2.528HisLeu: 2.528 ± 0.039	0.494HisMet: 0.494 ± 0.019	0.827HisAsn: 0.827 ± 0.029	1.505HisPro: 1.505 ± 0.035	1.472HisGln: 1.472 ± 0.031	1.626HisArg: 1.626 ± 0.033	1.402HisSer: 1.402 ± 0.03	1.124HisThr: 1.124 ± 0.028	1.089HisVal: 1.089 ± 0.027	0.539HisTrp: 0.539 ± 0.022	0.952HisTyr: 0.952 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.265IleAla: 5.265 ± 0.069	0.498IleCys: 0.498 ± 0.019	3.189IleAsp: 3.189 ± 0.052	3.431IleGlu: 3.431 ± 0.057	1.279IlePhe: 1.279 ± 0.033	3.938IleGly: 3.938 ± 0.049	1.05IleHis: 1.05 ± 0.027	1.785IleIle: 1.785 ± 0.045	1.656IleLys: 1.656 ± 0.04	4.037IleLeu: 4.037 ± 0.058	0.782IleMet: 0.782 ± 0.028	1.872IleAsn: 1.872 ± 0.039	2.194IlePro: 2.194 ± 0.04	1.855IleGln: 1.855 ± 0.035	2.616IleArg: 2.616 ± 0.045	2.87IleSer: 2.87 ± 0.045	2.722IleThr: 2.722 ± 0.05	2.656IleVal: 2.656 ± 0.049	0.553IleTrp: 0.553 ± 0.021	1.178IleTyr: 1.178 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.18LysAla: 4.18 ± 0.071	0.187LysCys: 0.187 ± 0.011	1.692LysAsp: 1.692 ± 0.038	2.004LysGlu: 2.004 ± 0.042	0.858LysPhe: 0.858 ± 0.024	2.668LysGly: 2.668 ± 0.044	0.809LysHis: 0.809 ± 0.023	1.547LysIle: 1.547 ± 0.033	1.298LysLys: 1.298 ± 0.039	3.754LysLeu: 3.754 ± 0.057	0.883LysMet: 0.883 ± 0.023	0.905LysAsn: 0.905 ± 0.026	1.957LysPro: 1.957 ± 0.039	1.943LysGln: 1.943 ± 0.04	2.35LysArg: 2.35 ± 0.046	1.746LysSer: 1.746 ± 0.038	1.724LysThr: 1.724 ± 0.034	2.767LysVal: 2.767 ± 0.051	0.342LysTrp: 0.342 ± 0.014	0.775LysTyr: 0.775 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.214LeuAla: 14.214 ± 0.123	1.257LeuCys: 1.257 ± 0.033	6.391LeuAsp: 6.391 ± 0.07	6.746LeuGlu: 6.746 ± 0.071	3.972LeuPhe: 3.972 ± 0.057	8.503LeuGly: 8.503 ± 0.08	2.307LeuHis: 2.307 ± 0.041	4.7LeuIle: 4.7 ± 0.064	4.067LeuLys: 4.067 ± 0.061	12.712LeuLeu: 12.712 ± 0.158	3.096LeuMet: 3.096 ± 0.048	3.63LeuAsn: 3.63 ± 0.052	6.081LeuPro: 6.081 ± 0.073	4.609LeuGln: 4.609 ± 0.069	5.767LeuArg: 5.767 ± 0.069	7.841LeuSer: 7.841 ± 0.096	6.303LeuThr: 6.303 ± 0.069	8.256LeuVal: 8.256 ± 0.089	1.455LeuTrp: 1.455 ± 0.041	2.804LeuTyr: 2.804 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	3.371MetAla: 3.371 ± 0.056	0.166MetCys: 0.166 ± 0.011	1.324MetAsp: 1.324 ± 0.029	1.424MetGlu: 1.424 ± 0.032	0.687MetPhe: 0.687 ± 0.024	1.961MetGly: 1.961 ± 0.038	0.471MetHis: 0.471 ± 0.019	1.16MetIle: 1.16 ± 0.028	1.127MetLys: 1.127 ± 0.027	2.862MetLeu: 2.862 ± 0.045	0.792MetMet: 0.792 ± 0.026	0.815MetAsn: 0.815 ± 0.023	1.248MetPro: 1.248 ± 0.027	1.069MetGln: 1.069 ± 0.03	1.338MetArg: 1.338 ± 0.029	1.675MetSer: 1.675 ± 0.036	1.621MetThr: 1.621 ± 0.034	2.021MetVal: 2.021 ± 0.041	0.239MetTrp: 0.239 ± 0.013	0.401MetTyr: 0.401 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.135AsnAla: 3.135 ± 0.056	0.342AsnCys: 0.342 ± 0.019	1.768AsnAsp: 1.768 ± 0.04	1.705AsnGlu: 1.705 ± 0.038	1.052AsnPhe: 1.052 ± 0.03	2.69AsnGly: 2.69 ± 0.048	0.792AsnHis: 0.792 ± 0.022	1.433AsnIle: 1.433 ± 0.034	1.071AsnLys: 1.071 ± 0.03	3.463AsnLeu: 3.463 ± 0.054	0.663AsnMet: 0.663 ± 0.022	1.146AsnAsn: 1.146 ± 0.031	2.047AsnPro: 2.047 ± 0.033	1.734AsnGln: 1.734 ± 0.034	2.007AsnArg: 2.007 ± 0.038	1.679AsnSer: 1.679 ± 0.038	1.578AsnThr: 1.578 ± 0.033	1.907AsnVal: 1.907 ± 0.04	0.523AsnTrp: 0.523 ± 0.022	0.951AsnTyr: 0.951 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	4.716ProAla: 4.716 ± 0.066	0.386ProCys: 0.386 ± 0.016	2.945ProAsp: 2.945 ± 0.052	3.886ProGlu: 3.886 ± 0.053	1.717ProPhe: 1.717 ± 0.033	3.738ProGly: 3.738 ± 0.057	1.08ProHis: 1.08 ± 0.025	2.088ProIle: 2.088 ± 0.035	1.727ProLys: 1.727 ± 0.038	5.384ProLeu: 5.384 ± 0.067	1.381ProMet: 1.381 ± 0.029	1.504ProAsn: 1.504 ± 0.035	1.693ProPro: 1.693 ± 0.049	2.395ProGln: 2.395 ± 0.042	2.103ProArg: 2.103 ± 0.042	2.819ProSer: 2.819 ± 0.051	2.32ProThr: 2.32 ± 0.041	3.816ProVal: 3.816 ± 0.065	0.75ProTrp: 0.75 ± 0.026	1.291ProTyr: 1.291 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	6.45GlnAla: 6.45 ± 0.083	0.552GlnCys: 0.552 ± 0.02	2.3GlnAsp: 2.3 ± 0.043	2.418GlnGlu: 2.418 ± 0.045	1.824GlnPhe: 1.824 ± 0.04	4.329GlnGly: 4.329 ± 0.06	1.424GlnHis: 1.424 ± 0.03	2.253GlnIle: 2.253 ± 0.042	1.253GlnLys: 1.253 ± 0.033	6.646GlnLeu: 6.646 ± 0.093	1.398GlnMet: 1.398 ± 0.033	1.089GlnAsn: 1.089 ± 0.035	2.73GlnPro: 2.73 ± 0.052	4.192GlnGln: 4.192 ± 0.088	3.948GlnArg: 3.948 ± 0.067	2.92GlnSer: 2.92 ± 0.055	2.248GlnThr: 2.248 ± 0.04	3.792GlnVal: 3.792 ± 0.057	1.1GlnTrp: 1.1 ± 0.033	1.345GlnTyr: 1.345 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	5.113ArgAla: 5.113 ± 0.063	0.653ArgCys: 0.653 ± 0.023	3.055ArgAsp: 3.055 ± 0.053	3.315ArgGlu: 3.315 ± 0.055	2.873ArgPhe: 2.873 ± 0.041	3.535ArgGly: 3.535 ± 0.055	1.685ArgHis: 1.685 ± 0.037	2.975ArgIle: 2.975 ± 0.057	1.856ArgLys: 1.856 ± 0.04	6.907ArgLeu: 6.907 ± 0.08	1.496ArgMet: 1.496 ± 0.034	1.818ArgAsn: 1.818 ± 0.034	2.523ArgPro: 2.523 ± 0.045	3.637ArgGln: 3.637 ± 0.061	3.809ArgArg: 3.809 ± 0.069	3.11ArgSer: 3.11 ± 0.053	2.521ArgThr: 2.521 ± 0.037	3.825ArgVal: 3.825 ± 0.058	1.119ArgTrp: 1.119 ± 0.036	2.203ArgTyr: 2.203 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.778SerAla: 5.778 ± 0.062	0.615SerCys: 0.615 ± 0.026	3.515SerAsp: 3.515 ± 0.06	3.844SerGlu: 3.844 ± 0.062	2.11SerPhe: 2.11 ± 0.041	5.109SerGly: 5.109 ± 0.075	1.451SerHis: 1.451 ± 0.038	2.417SerIle: 2.417 ± 0.042	1.917SerLys: 1.917 ± 0.037	6.792SerLeu: 6.792 ± 0.075	1.407SerMet: 1.407 ± 0.03	1.865SerAsn: 1.865 ± 0.034	2.682SerPro: 2.682 ± 0.044	3.109SerGln: 3.109 ± 0.046	3.192SerArg: 3.192 ± 0.045	3.294SerSer: 3.294 ± 0.057	2.59SerThr: 2.59 ± 0.044	4.118SerVal: 4.118 ± 0.056	0.905SerTrp: 0.905 ± 0.024	1.759SerTyr: 1.759 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	4.706ThrAla: 4.706 ± 0.069	0.419ThrCys: 0.419 ± 0.019	2.762ThrAsp: 2.762 ± 0.063	3.175ThrGlu: 3.175 ± 0.049	1.662ThrPhe: 1.662 ± 0.031	4.188ThrGly: 4.188 ± 0.064	1.04ThrHis: 1.04 ± 0.026	2.286ThrIle: 2.286 ± 0.043	1.324ThrLys: 1.324 ± 0.03	6.945ThrLeu: 6.945 ± 0.081	1.043ThrMet: 1.043 ± 0.029	1.361ThrAsn: 1.361 ± 0.035	2.979ThrPro: 2.979 ± 0.045	2.279ThrGln: 2.279 ± 0.039	2.503ThrArg: 2.503 ± 0.043	2.395ThrSer: 2.395 ± 0.042	2.503ThrThr: 2.503 ± 0.054	3.789ThrVal: 3.789 ± 0.065	0.583ThrTrp: 0.583 ± 0.021	1.18ThrTyr: 1.18 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.798ValAla: 7.798 ± 0.074	0.703ValCys: 0.703 ± 0.024	4.155ValAsp: 4.155 ± 0.055	4.675ValGlu: 4.675 ± 0.062	2.364ValPhe: 2.364 ± 0.047	4.896ValGly: 4.896 ± 0.068	1.268ValHis: 1.268 ± 0.03	3.617ValIle: 3.617 ± 0.054	2.42ValLys: 2.42 ± 0.045	7.625ValLeu: 7.625 ± 0.087	1.985ValMet: 1.985 ± 0.038	2.291ValAsn: 2.291 ± 0.045	3.126ValPro: 3.126 ± 0.049	2.685ValGln: 2.685 ± 0.048	3.618ValArg: 3.618 ± 0.045	4.294ValSer: 4.294 ± 0.061	3.899ValThr: 3.899 ± 0.069	5.49ValVal: 5.49 ± 0.065	0.807ValTrp: 0.807 ± 0.026	1.643ValTyr: 1.643 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.169TrpAla: 1.169 ± 0.033	0.177TrpCys: 0.177 ± 0.011	0.766TrpAsp: 0.766 ± 0.023	0.564TrpGlu: 0.564 ± 0.02	0.557TrpPhe: 0.557 ± 0.021	1.044TrpGly: 1.044 ± 0.029	0.478TrpHis: 0.478 ± 0.02	0.548TrpIle: 0.548 ± 0.026	0.315TrpLys: 0.315 ± 0.016	2.168TrpLeu: 2.168 ± 0.049	0.387TrpMet: 0.387 ± 0.014	0.374TrpAsn: 0.374 ± 0.017	0.71TrpPro: 0.71 ± 0.023	1.443TrpGln: 1.443 ± 0.034	1.054TrpArg: 1.054 ± 0.033	0.813TrpSer: 0.813 ± 0.029	0.568TrpThr: 0.568 ± 0.022	0.954TrpVal: 0.954 ± 0.028	0.268TrpTrp: 0.268 ± 0.016	0.414TrpTyr: 0.414 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.292TyrAla: 2.292 ± 0.042	0.345TyrCys: 0.345 ± 0.016	1.671TyrAsp: 1.671 ± 0.038	1.279TyrGlu: 1.279 ± 0.034	1.084TyrPhe: 1.084 ± 0.029	2.259TyrGly: 2.259 ± 0.047	0.779TyrHis: 0.779 ± 0.022	1.024TyrIle: 1.024 ± 0.027	0.727TyrLys: 0.727 ± 0.027	3.505TyrLeu: 3.505 ± 0.051	0.499TyrMet: 0.499 ± 0.019	0.866TyrAsn: 0.866 ± 0.025	1.414TyrPro: 1.414 ± 0.035	1.907TyrGln: 1.907 ± 0.039	2.216TyrArg: 2.216 ± 0.043	1.566TyrSer: 1.566 ± 0.037	1.275TyrThr: 1.275 ± 0.033	1.563TyrVal: 1.563 ± 0.036	0.457TyrTrp: 0.457 ± 0.017	0.875TyrTyr: 0.875 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4625 proteins (1462360 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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