Amino acid dipepetide frequency for Alkaliphilus oremlandii (strain OhILAs) (Clostridium oremlandii (strain OhILAs))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.806AlaAla: 4.806 ± 0.114	0.672AlaCys: 0.672 ± 0.029	2.935AlaAsp: 2.935 ± 0.063	4.264AlaGlu: 4.264 ± 0.074	2.672AlaPhe: 2.672 ± 0.065	4.607AlaGly: 4.607 ± 0.103	1.061AlaHis: 1.061 ± 0.039	6.097AlaIle: 6.097 ± 0.096	4.627AlaLys: 4.627 ± 0.079	6.801AlaLeu: 6.801 ± 0.108	2.15AlaMet: 2.15 ± 0.055	2.674AlaAsn: 2.674 ± 0.057	1.74AlaPro: 1.74 ± 0.048	1.88AlaGln: 1.88 ± 0.051	2.254AlaArg: 2.254 ± 0.051	3.584AlaSer: 3.584 ± 0.071	3.398AlaThr: 3.398 ± 0.077	4.647AlaVal: 4.647 ± 0.093	0.37AlaTrp: 0.37 ± 0.021	2.273AlaTyr: 2.273 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.505CysAla: 0.505 ± 0.028	0.137CysCys: 0.137 ± 0.014	0.499CysAsp: 0.499 ± 0.025	0.539CysGlu: 0.539 ± 0.031	0.356CysPhe: 0.356 ± 0.022	0.926CysGly: 0.926 ± 0.038	0.244CysHis: 0.244 ± 0.015	0.906CysIle: 0.906 ± 0.033	0.68CysLys: 0.68 ± 0.03	0.661CysLeu: 0.661 ± 0.029	0.225CysMet: 0.225 ± 0.017	0.491CysAsn: 0.491 ± 0.026	0.501CysPro: 0.501 ± 0.032	0.255CysGln: 0.255 ± 0.019	0.385CysArg: 0.385 ± 0.026	0.671CysSer: 0.671 ± 0.03	0.5CysThr: 0.5 ± 0.024	0.543CysVal: 0.543 ± 0.026	0.063CysTrp: 0.063 ± 0.009	0.335CysTyr: 0.335 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.047AspAla: 3.047 ± 0.072	0.507AspCys: 0.507 ± 0.024	2.135AspAsp: 2.135 ± 0.062	4.282AspGlu: 4.282 ± 0.084	2.581AspPhe: 2.581 ± 0.066	3.491AspGly: 3.491 ± 0.077	1.124AspHis: 1.124 ± 0.038	5.614AspIle: 5.614 ± 0.086	3.748AspLys: 3.748 ± 0.06	5.303AspLeu: 5.303 ± 0.086	1.577AspMet: 1.577 ± 0.045	2.11AspAsn: 2.11 ± 0.05	1.576AspPro: 1.576 ± 0.049	1.506AspGln: 1.506 ± 0.039	2.408AspArg: 2.408 ± 0.059	2.703AspSer: 2.703 ± 0.058	2.565AspThr: 2.565 ± 0.058	3.676AspVal: 3.676 ± 0.075	0.425AspTrp: 0.425 ± 0.023	2.259AspTyr: 2.259 ± 0.056	0.0AspXaa: 0.0 ± 0.0
Glu	5.076GluAla: 5.076 ± 0.077	0.481GluCys: 0.481 ± 0.025	4.712GluAsp: 4.712 ± 0.082	7.787GluGlu: 7.787 ± 0.108	2.639GluPhe: 2.639 ± 0.054	4.857GluGly: 4.857 ± 0.081	1.228GluHis: 1.228 ± 0.039	7.828GluIle: 7.828 ± 0.096	7.269GluLys: 7.269 ± 0.109	6.752GluLeu: 6.752 ± 0.102	2.207GluMet: 2.207 ± 0.05	4.86GluAsn: 4.86 ± 0.071	1.657GluPro: 1.657 ± 0.049	2.216GluGln: 2.216 ± 0.057	3.178GluArg: 3.178 ± 0.069	3.605GluSer: 3.605 ± 0.062	3.235GluThr: 3.235 ± 0.064	5.294GluVal: 5.294 ± 0.085	0.492GluTrp: 0.492 ± 0.026	2.829GluTyr: 2.829 ± 0.065	0.0GluXaa: 0.0 ± 0.0
Phe	2.479PheAla: 2.479 ± 0.065	0.392PheCys: 0.392 ± 0.022	2.195PheAsp: 2.195 ± 0.053	2.686PheGlu: 2.686 ± 0.058	1.775PhePhe: 1.775 ± 0.052	2.841PheGly: 2.841 ± 0.062	0.762PheHis: 0.762 ± 0.033	4.203PheIle: 4.203 ± 0.089	3.027PheLys: 3.027 ± 0.064	3.788PheLeu: 3.788 ± 0.076	1.139PheMet: 1.139 ± 0.031	2.365PheAsn: 2.365 ± 0.055	1.276PhePro: 1.276 ± 0.042	1.155PheGln: 1.155 ± 0.034	1.315PheArg: 1.315 ± 0.038	3.0PheSer: 3.0 ± 0.063	2.313PheThr: 2.313 ± 0.052	2.674PheVal: 2.674 ± 0.055	0.296PheTrp: 0.296 ± 0.017	1.641PheTyr: 1.641 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	4.953GlyAla: 4.953 ± 0.108	0.853GlyCys: 0.853 ± 0.038	3.239GlyAsp: 3.239 ± 0.063	4.554GlyGlu: 4.554 ± 0.078	3.158GlyPhe: 3.158 ± 0.059	4.775GlyGly: 4.775 ± 0.102	1.227GlyHis: 1.227 ± 0.039	7.038GlyIle: 7.038 ± 0.112	5.381GlyLys: 5.381 ± 0.072	6.044GlyLeu: 6.044 ± 0.09	2.079GlyMet: 2.079 ± 0.056	3.294GlyAsn: 3.294 ± 0.061	1.636GlyPro: 1.636 ± 0.066	1.92GlyGln: 1.92 ± 0.048	2.758GlyArg: 2.758 ± 0.057	3.927GlySer: 3.927 ± 0.071	3.911GlyThr: 3.911 ± 0.076	4.822GlyVal: 4.822 ± 0.074	0.499GlyTrp: 0.499 ± 0.023	2.971GlyTyr: 2.971 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	0.854HisAla: 0.854 ± 0.03	0.229HisCys: 0.229 ± 0.018	0.788HisAsp: 0.788 ± 0.031	1.031HisGlu: 1.031 ± 0.04	0.719HisPhe: 0.719 ± 0.03	1.271HisGly: 1.271 ± 0.043	0.52HisHis: 0.52 ± 0.024	1.787HisIle: 1.787 ± 0.051	1.253HisLys: 1.253 ± 0.039	1.655HisLeu: 1.655 ± 0.047	0.56HisMet: 0.56 ± 0.024	0.892HisAsn: 0.892 ± 0.037	0.866HisPro: 0.866 ± 0.027	0.573HisGln: 0.573 ± 0.027	0.858HisArg: 0.858 ± 0.03	1.061HisSer: 1.061 ± 0.038	0.892HisThr: 0.892 ± 0.037	1.061HisVal: 1.061 ± 0.035	0.166HisTrp: 0.166 ± 0.015	0.719HisTyr: 0.719 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.361IleAla: 6.361 ± 0.103	0.927IleCys: 0.927 ± 0.036	5.254IleAsp: 5.254 ± 0.082	7.642IleGlu: 7.642 ± 0.11	3.842IlePhe: 3.842 ± 0.072	6.624IleGly: 6.624 ± 0.111	1.99IleHis: 1.99 ± 0.05	8.1IleIle: 8.1 ± 0.129	6.794IleLys: 6.794 ± 0.088	9.343IleLeu: 9.343 ± 0.135	2.322IleMet: 2.322 ± 0.05	4.417IleAsn: 4.417 ± 0.067	3.533IlePro: 3.533 ± 0.056	2.969IleGln: 2.969 ± 0.063	3.566IleArg: 3.566 ± 0.066	6.371IleSer: 6.371 ± 0.096	4.927IleThr: 4.927 ± 0.071	6.45IleVal: 6.45 ± 0.1	0.521IleTrp: 0.521 ± 0.026	3.254IleTyr: 3.254 ± 0.064	0.0IleXaa: 0.0 ± 0.0
Lys	4.752LysAla: 4.752 ± 0.08	0.559LysCys: 0.559 ± 0.031	4.823LysAsp: 4.823 ± 0.077	8.234LysGlu: 8.234 ± 0.115	2.37LysPhe: 2.37 ± 0.054	4.959LysGly: 4.959 ± 0.07	1.135LysHis: 1.135 ± 0.032	7.244LysIle: 7.244 ± 0.101	6.571LysLys: 6.571 ± 0.095	6.528LysLeu: 6.528 ± 0.104	2.282LysMet: 2.282 ± 0.051	4.814LysAsn: 4.814 ± 0.083	2.017LysPro: 2.017 ± 0.052	2.187LysGln: 2.187 ± 0.055	2.919LysArg: 2.919 ± 0.059	4.153LysSer: 4.153 ± 0.069	3.616LysThr: 3.616 ± 0.069	5.296LysVal: 5.296 ± 0.095	0.531LysTrp: 0.531 ± 0.029	2.903LysTyr: 2.903 ± 0.06	0.0LysXaa: 0.0 ± 0.0
Leu	5.75LeuAla: 5.75 ± 0.101	0.925LeuCys: 0.925 ± 0.035	5.149LeuAsp: 5.149 ± 0.084	7.365LeuGlu: 7.365 ± 0.111	3.892LeuPhe: 3.892 ± 0.083	6.705LeuGly: 6.705 ± 0.095	1.315LeuHis: 1.315 ± 0.039	7.874LeuIle: 7.874 ± 0.103	7.672LeuLys: 7.672 ± 0.096	8.545LeuLeu: 8.545 ± 0.12	2.689LeuMet: 2.689 ± 0.046	5.203LeuAsn: 5.203 ± 0.082	3.084LeuPro: 3.084 ± 0.07	2.686LeuGln: 2.686 ± 0.059	3.51LeuArg: 3.51 ± 0.059	6.54LeuSer: 6.54 ± 0.091	4.594LeuThr: 4.594 ± 0.08	5.675LeuVal: 5.675 ± 0.088	0.66LeuTrp: 0.66 ± 0.03	3.074LeuTyr: 3.074 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	2.17MetAla: 2.17 ± 0.055	0.184MetCys: 0.184 ± 0.014	2.0MetAsp: 2.0 ± 0.053	2.534MetGlu: 2.534 ± 0.055	0.887MetPhe: 0.887 ± 0.033	2.094MetGly: 2.094 ± 0.056	0.367MetHis: 0.367 ± 0.02	2.416MetIle: 2.416 ± 0.057	2.641MetLys: 2.641 ± 0.058	2.305MetLeu: 2.305 ± 0.055	0.836MetMet: 0.836 ± 0.035	1.719MetAsn: 1.719 ± 0.044	0.947MetPro: 0.947 ± 0.037	0.74MetGln: 0.74 ± 0.03	0.96MetArg: 0.96 ± 0.036	1.594MetSer: 1.594 ± 0.046	1.341MetThr: 1.341 ± 0.04	2.123MetVal: 2.123 ± 0.053	0.12MetTrp: 0.12 ± 0.011	0.696MetTyr: 0.696 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.926AsnAla: 2.926 ± 0.056	0.513AsnCys: 0.513 ± 0.027	2.131AsnAsp: 2.131 ± 0.05	3.608AsnGlu: 3.608 ± 0.073	2.146AsnPhe: 2.146 ± 0.043	3.165AsnGly: 3.165 ± 0.065	1.081AsnHis: 1.081 ± 0.034	5.593AsnIle: 5.593 ± 0.088	4.327AsnLys: 4.327 ± 0.087	4.961AsnLeu: 4.961 ± 0.08	1.545AsnMet: 1.545 ± 0.042	2.793AsnAsn: 2.793 ± 0.063	2.166AsnPro: 2.166 ± 0.057	1.792AsnGln: 1.792 ± 0.043	2.239AsnArg: 2.239 ± 0.05	2.807AsnSer: 2.807 ± 0.062	2.757AsnThr: 2.757 ± 0.057	3.123AsnVal: 3.123 ± 0.062	0.407AsnTrp: 0.407 ± 0.024	1.982AsnTyr: 1.982 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	1.8ProAla: 1.8 ± 0.052	0.296ProCys: 0.296 ± 0.02	1.507ProAsp: 1.507 ± 0.048	2.501ProGlu: 2.501 ± 0.064	1.472ProPhe: 1.472 ± 0.039	1.916ProGly: 1.916 ± 0.053	0.575ProHis: 0.575 ± 0.028	2.931ProIle: 2.931 ± 0.063	2.219ProLys: 2.219 ± 0.051	2.772ProLeu: 2.772 ± 0.06	0.946ProMet: 0.946 ± 0.034	1.584ProAsn: 1.584 ± 0.047	0.834ProPro: 0.834 ± 0.036	1.038ProGln: 1.038 ± 0.038	1.025ProArg: 1.025 ± 0.035	2.001ProSer: 2.001 ± 0.048	1.791ProThr: 1.791 ± 0.066	2.352ProVal: 2.352 ± 0.055	0.27ProTrp: 0.27 ± 0.019	1.37ProTyr: 1.37 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	1.647GlnAla: 1.647 ± 0.044	0.301GlnCys: 0.301 ± 0.02	1.442GlnAsp: 1.442 ± 0.041	2.245GlnGlu: 2.245 ± 0.05	1.163GlnPhe: 1.163 ± 0.037	1.937GlnGly: 1.937 ± 0.049	0.505GlnHis: 0.505 ± 0.027	2.624GlnIle: 2.624 ± 0.055	2.301GlnLys: 2.301 ± 0.047	2.925GlnLeu: 2.925 ± 0.069	0.854GlnMet: 0.854 ± 0.03	1.621GlnAsn: 1.621 ± 0.042	0.8GlnPro: 0.8 ± 0.031	1.026GlnGln: 1.026 ± 0.04	1.309GlnArg: 1.309 ± 0.039	1.698GlnSer: 1.698 ± 0.049	1.23GlnThr: 1.23 ± 0.035	1.913GlnVal: 1.913 ± 0.047	0.349GlnTrp: 0.349 ± 0.02	1.382GlnTyr: 1.382 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	2.344ArgAla: 2.344 ± 0.055	0.378ArgCys: 0.378 ± 0.023	2.051ArgAsp: 2.051 ± 0.055	3.291ArgGlu: 3.291 ± 0.063	1.64ArgPhe: 1.64 ± 0.044	2.437ArgGly: 2.437 ± 0.047	0.553ArgHis: 0.553 ± 0.026	3.722ArgIle: 3.722 ± 0.07	3.168ArgLys: 3.168 ± 0.06	3.483ArgLeu: 3.483 ± 0.068	1.252ArgMet: 1.252 ± 0.035	2.09ArgAsn: 2.09 ± 0.051	1.079ArgPro: 1.079 ± 0.04	1.191ArgGln: 1.191 ± 0.038	1.673ArgArg: 1.673 ± 0.045	1.983ArgSer: 1.983 ± 0.048	1.863ArgThr: 1.863 ± 0.046	2.567ArgVal: 2.567 ± 0.059	0.276ArgTrp: 0.276 ± 0.019	1.613ArgTyr: 1.613 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	3.525SerAla: 3.525 ± 0.067	0.548SerCys: 0.548 ± 0.028	2.805SerAsp: 2.805 ± 0.062	3.678SerGlu: 3.678 ± 0.067	2.908SerPhe: 2.908 ± 0.061	4.178SerGly: 4.178 ± 0.08	1.11SerHis: 1.11 ± 0.032	6.258SerIle: 6.258 ± 0.094	4.828SerLys: 4.828 ± 0.072	5.673SerLeu: 5.673 ± 0.094	1.764SerMet: 1.764 ± 0.045	3.155SerAsn: 3.155 ± 0.067	1.819SerPro: 1.819 ± 0.047	1.715SerGln: 1.715 ± 0.035	2.223SerArg: 2.223 ± 0.053	3.832SerSer: 3.832 ± 0.066	3.152SerThr: 3.152 ± 0.063	3.73SerVal: 3.73 ± 0.069	0.404SerTrp: 0.404 ± 0.02	2.25SerTyr: 2.25 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	3.415ThrAla: 3.415 ± 0.067	0.405ThrCys: 0.405 ± 0.023	2.354ThrAsp: 2.354 ± 0.053	3.409ThrGlu: 3.409 ± 0.06	2.066ThrPhe: 2.066 ± 0.047	4.242ThrGly: 4.242 ± 0.14	0.838ThrHis: 0.838 ± 0.032	4.81ThrIle: 4.81 ± 0.083	3.423ThrLys: 3.423 ± 0.062	4.936ThrLeu: 4.936 ± 0.071	1.38ThrMet: 1.38 ± 0.043	2.468ThrAsn: 2.468 ± 0.056	1.934ThrPro: 1.934 ± 0.059	1.219ThrGln: 1.219 ± 0.04	1.779ThrArg: 1.779 ± 0.048	3.043ThrSer: 3.043 ± 0.062	2.934ThrThr: 2.934 ± 0.068	3.971ThrVal: 3.971 ± 0.084	0.348ThrTrp: 0.348 ± 0.02	1.786ThrTyr: 1.786 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.63ValAla: 4.63 ± 0.084	0.64ValCys: 0.64 ± 0.028	4.024ValAsp: 4.024 ± 0.072	5.267ValGlu: 5.267 ± 0.085	2.942ValPhe: 2.942 ± 0.064	4.814ValGly: 4.814 ± 0.094	1.205ValHis: 1.205 ± 0.038	6.016ValIle: 6.016 ± 0.089	4.833ValLys: 4.833 ± 0.074	6.449ValLeu: 6.449 ± 0.083	1.661ValMet: 1.661 ± 0.049	3.158ValAsn: 3.158 ± 0.065	2.293ValPro: 2.293 ± 0.056	1.875ValGln: 1.875 ± 0.039	2.323ValArg: 2.323 ± 0.058	4.251ValSer: 4.251 ± 0.074	3.388ValThr: 3.388 ± 0.078	5.087ValVal: 5.087 ± 0.099	0.416ValTrp: 0.416 ± 0.021	2.253ValTyr: 2.253 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.449TrpAla: 0.449 ± 0.02	0.086TrpCys: 0.086 ± 0.011	0.407TrpAsp: 0.407 ± 0.023	0.487TrpGlu: 0.487 ± 0.025	0.272TrpPhe: 0.272 ± 0.016	0.523TrpGly: 0.523 ± 0.025	0.157TrpHis: 0.157 ± 0.014	0.703TrpIle: 0.703 ± 0.033	0.51TrpLys: 0.51 ± 0.028	0.604TrpLeu: 0.604 ± 0.023	0.221TrpMet: 0.221 ± 0.016	0.399TrpAsn: 0.399 ± 0.023	0.156TrpPro: 0.156 ± 0.014	0.242TrpGln: 0.242 ± 0.015	0.268TrpArg: 0.268 ± 0.018	0.386TrpSer: 0.386 ± 0.023	0.341TrpThr: 0.341 ± 0.023	0.423TrpVal: 0.423 ± 0.023	0.071TrpTrp: 0.071 ± 0.009	0.26TrpTyr: 0.26 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.023TyrAla: 2.023 ± 0.049	0.386TyrCys: 0.386 ± 0.021	2.186TyrAsp: 2.186 ± 0.057	2.799TyrGlu: 2.799 ± 0.052	1.823TyrPhe: 1.823 ± 0.05	2.676TyrGly: 2.676 ± 0.06	0.758TyrHis: 0.758 ± 0.035	3.446TyrIle: 3.446 ± 0.078	2.62TyrLys: 2.62 ± 0.059	3.381TyrLeu: 3.381 ± 0.069	0.984TyrMet: 0.984 ± 0.033	1.955TyrAsn: 1.955 ± 0.049	1.285TyrPro: 1.285 ± 0.038	1.086TyrGln: 1.086 ± 0.037	1.705TyrArg: 1.705 ± 0.05	2.344TyrSer: 2.344 ± 0.05	2.014TyrThr: 2.014 ± 0.045	2.097TyrVal: 2.097 ± 0.049	0.281TyrTrp: 0.281 ± 0.019	1.592TyrTyr: 1.592 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2828 proteins (874563 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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