Amino acid dipepetide frequency for Sulfolobus islandicus rod-shaped virus 1 (SIRV-1) (Sulfolobus virus SIRV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.0AlaCys: 0.0 ± 0.0
1.76AlaAsp: 1.76 ± 0.482
2.229AlaGlu: 2.229 ± 0.673
3.167AlaPhe: 3.167 ± 0.638
1.525AlaGly: 1.525 ± 0.475
0.117AlaHis: 0.117 ± 0.143
5.865AlaIle: 5.865 ± 0.985
5.161AlaLys: 5.161 ± 0.802
4.927AlaLeu: 4.927 ± 0.724
0.587AlaMet: 0.587 ± 0.349
2.815AlaAsn: 2.815 ± 0.4
0.938AlaPro: 0.938 ± 0.31
1.994AlaGln: 1.994 ± 0.569
1.76AlaArg: 1.76 ± 0.465
1.877AlaSer: 1.877 ± 0.452
1.408AlaThr: 1.408 ± 0.449
2.581AlaVal: 2.581 ± 0.599
0.821AlaTrp: 0.821 ± 0.278
2.111AlaTyr: 2.111 ± 0.394
0.0AlaXaa: 0.0 ± 0.0
Cys
0.117CysAla: 0.117 ± 0.121
0.117CysCys: 0.117 ± 0.103
0.235CysAsp: 0.235 ± 0.155
0.938CysGlu: 0.938 ± 0.427
0.235CysPhe: 0.235 ± 0.163
0.704CysGly: 0.704 ± 0.281
0.117CysHis: 0.117 ± 0.13
1.056CysIle: 1.056 ± 0.359
0.938CysLys: 0.938 ± 0.404
0.704CysLeu: 0.704 ± 0.312
0.117CysMet: 0.117 ± 0.14
0.821CysAsn: 0.821 ± 0.303
0.117CysPro: 0.117 ± 0.129
0.235CysGln: 0.235 ± 0.16
0.235CysArg: 0.235 ± 0.17
0.117CysSer: 0.117 ± 0.106
0.117CysThr: 0.117 ± 0.124
0.469CysVal: 0.469 ± 0.27
0.0CysTrp: 0.0 ± 0.0
0.469CysTyr: 0.469 ± 0.214
0.0CysXaa: 0.0 ± 0.0
Asp
1.173AspAla: 1.173 ± 0.302
0.469AspCys: 0.469 ± 0.263
1.76AspAsp: 1.76 ± 0.549
2.815AspGlu: 2.815 ± 0.455
3.05AspPhe: 3.05 ± 0.625
1.29AspGly: 1.29 ± 0.362
0.587AspHis: 0.587 ± 0.286
5.513AspIle: 5.513 ± 0.837
4.223AspLys: 4.223 ± 0.595
6.217AspLeu: 6.217 ± 0.579
1.056AspMet: 1.056 ± 0.362
4.223AspAsn: 4.223 ± 0.883
1.173AspPro: 1.173 ± 0.308
1.408AspGln: 1.408 ± 0.45
1.173AspArg: 1.173 ± 0.326
2.698AspSer: 2.698 ± 0.426
1.994AspThr: 1.994 ± 0.487
1.877AspVal: 1.877 ± 0.473
0.352AspTrp: 0.352 ± 0.189
2.581AspTyr: 2.581 ± 0.407
0.0AspXaa: 0.0 ± 0.0
Glu
1.173GluAla: 1.173 ± 0.328
0.352GluCys: 0.352 ± 0.232
2.815GluAsp: 2.815 ± 0.704
5.748GluGlu: 5.748 ± 1.047
4.457GluPhe: 4.457 ± 0.916
1.76GluGly: 1.76 ± 0.407
0.587GluHis: 0.587 ± 0.228
10.205GluIle: 10.205 ± 1.351
7.273GluLys: 7.273 ± 1.154
6.804GluLeu: 6.804 ± 1.243
1.29GluMet: 1.29 ± 0.464
4.575GluAsn: 4.575 ± 0.639
1.173GluPro: 1.173 ± 0.326
2.111GluGln: 2.111 ± 0.446
1.525GluArg: 1.525 ± 0.444
3.05GluSer: 3.05 ± 0.592
2.346GluThr: 2.346 ± 0.398
4.575GluVal: 4.575 ± 0.936
0.469GluTrp: 0.469 ± 0.22
4.692GluTyr: 4.692 ± 1.053
0.0GluXaa: 0.0 ± 0.0
Phe
2.463PheAla: 2.463 ± 0.657
1.056PheCys: 1.056 ± 0.421
3.167PheAsp: 3.167 ± 0.537
4.575PheGlu: 4.575 ± 0.794
2.463PhePhe: 2.463 ± 0.449
3.05PheGly: 3.05 ± 0.526
0.704PheHis: 0.704 ± 0.347
5.161PheIle: 5.161 ± 0.858
4.927PheLys: 4.927 ± 0.965
5.63PheLeu: 5.63 ± 0.914
1.29PheMet: 1.29 ± 0.3
3.636PheAsn: 3.636 ± 0.567
1.642PhePro: 1.642 ± 0.457
2.815PheGln: 2.815 ± 0.477
1.76PheArg: 1.76 ± 0.455
4.106PheSer: 4.106 ± 0.815
3.05PheThr: 3.05 ± 0.46
2.698PheVal: 2.698 ± 0.538
0.587PheTrp: 0.587 ± 0.311
3.519PheTyr: 3.519 ± 0.577
0.0PheXaa: 0.0 ± 0.0
Gly
1.642GlyAla: 1.642 ± 0.35
0.469GlyCys: 0.469 ± 0.213
1.76GlyAsp: 1.76 ± 0.39
2.346GlyGlu: 2.346 ± 0.465
2.933GlyPhe: 2.933 ± 0.553
1.76GlyGly: 1.76 ± 0.478
0.469GlyHis: 0.469 ± 0.231
5.748GlyIle: 5.748 ± 0.896
3.402GlyLys: 3.402 ± 0.554
3.402GlyLeu: 3.402 ± 0.545
1.29GlyMet: 1.29 ± 0.31
3.167GlyAsn: 3.167 ± 0.991
0.352GlyPro: 0.352 ± 0.25
1.76GlyGln: 1.76 ± 0.412
0.587GlyArg: 0.587 ± 0.247
2.229GlySer: 2.229 ± 0.562
2.463GlyThr: 2.463 ± 0.436
1.877GlyVal: 1.877 ± 0.53
0.352GlyTrp: 0.352 ± 0.187
2.463GlyTyr: 2.463 ± 0.65
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.704HisAsp: 0.704 ± 0.255
0.469HisGlu: 0.469 ± 0.234
0.352HisPhe: 0.352 ± 0.266
0.352HisGly: 0.352 ± 0.251
0.117HisHis: 0.117 ± 0.119
1.642HisIle: 1.642 ± 0.418
0.821HisLys: 0.821 ± 0.361
1.994HisLeu: 1.994 ± 0.502
0.235HisMet: 0.235 ± 0.144
0.821HisAsn: 0.821 ± 0.29
0.587HisPro: 0.587 ± 0.251
0.117HisGln: 0.117 ± 0.119
0.117HisArg: 0.117 ± 0.124
0.704HisSer: 0.704 ± 0.261
0.352HisThr: 0.352 ± 0.181
0.938HisVal: 0.938 ± 0.33
0.0HisTrp: 0.0 ± 0.0
0.587HisTyr: 0.587 ± 0.253
0.0HisXaa: 0.0 ± 0.0
Ile
6.804IleAla: 6.804 ± 0.931
0.821IleCys: 0.821 ± 0.344
5.865IleAsp: 5.865 ± 1.182
7.742IleGlu: 7.742 ± 0.838
5.865IlePhe: 5.865 ± 1.155
3.636IleGly: 3.636 ± 0.54
1.642IleHis: 1.642 ± 0.484
10.909IleIle: 10.909 ± 1.346
9.971IleLys: 9.971 ± 1.458
8.68IleLeu: 8.68 ± 0.984
0.821IleMet: 0.821 ± 0.286
10.205IleAsn: 10.205 ± 1.428
4.692IlePro: 4.692 ± 0.713
4.106IleGln: 4.106 ± 0.782
2.463IleArg: 2.463 ± 0.536
8.563IleSer: 8.563 ± 1.174
4.106IleThr: 4.106 ± 0.775
6.804IleVal: 6.804 ± 1.0
0.938IleTrp: 0.938 ± 0.242
5.865IleTyr: 5.865 ± 0.905
0.0IleXaa: 0.0 ± 0.0
Lys
2.463LysAla: 2.463 ± 0.617
0.587LysCys: 0.587 ± 0.286
4.34LysAsp: 4.34 ± 0.736
8.094LysGlu: 8.094 ± 1.2
4.106LysPhe: 4.106 ± 0.742
2.346LysGly: 2.346 ± 0.524
1.29LysHis: 1.29 ± 0.446
10.909LysIle: 10.909 ± 1.186
6.804LysLys: 6.804 ± 0.953
8.68LysLeu: 8.68 ± 1.16
2.463LysMet: 2.463 ± 0.767
5.279LysAsn: 5.279 ± 0.809
1.29LysPro: 1.29 ± 0.328
4.223LysGln: 4.223 ± 0.776
3.519LysArg: 3.519 ± 0.766
4.927LysSer: 4.927 ± 0.679
4.106LysThr: 4.106 ± 0.588
4.575LysVal: 4.575 ± 0.728
0.587LysTrp: 0.587 ± 0.217
4.927LysTyr: 4.927 ± 0.905
0.0LysXaa: 0.0 ± 0.0
Leu
5.044LeuAla: 5.044 ± 0.689
0.469LeuCys: 0.469 ± 0.234
5.396LeuAsp: 5.396 ± 0.633
6.1LeuGlu: 6.1 ± 0.986
5.161LeuPhe: 5.161 ± 0.951
3.988LeuGly: 3.988 ± 1.116
1.173LeuHis: 1.173 ± 0.323
9.032LeuIle: 9.032 ± 1.016
8.68LeuLys: 8.68 ± 1.322
9.384LeuLeu: 9.384 ± 1.481
1.994LeuMet: 1.994 ± 0.518
6.217LeuAsn: 6.217 ± 1.05
3.519LeuPro: 3.519 ± 0.557
5.748LeuGln: 5.748 ± 1.064
3.05LeuArg: 3.05 ± 0.605
6.921LeuSer: 6.921 ± 1.014
5.63LeuThr: 5.63 ± 0.818
3.754LeuVal: 3.754 ± 0.807
0.469LeuTrp: 0.469 ± 0.236
6.921LeuTyr: 6.921 ± 1.217
0.0LeuXaa: 0.0 ± 0.0
Met
0.704MetAla: 0.704 ± 0.324
0.117MetCys: 0.117 ± 0.119
1.173MetAsp: 1.173 ± 0.381
1.173MetGlu: 1.173 ± 0.35
1.056MetPhe: 1.056 ± 0.305
0.704MetGly: 0.704 ± 0.265
0.117MetHis: 0.117 ± 0.109
1.877MetIle: 1.877 ± 0.425
1.76MetLys: 1.76 ± 0.464
1.173MetLeu: 1.173 ± 0.306
0.117MetMet: 0.117 ± 0.124
2.111MetAsn: 2.111 ± 0.481
1.173MetPro: 1.173 ± 0.466
0.704MetGln: 0.704 ± 0.339
0.704MetArg: 0.704 ± 0.389
2.463MetSer: 2.463 ± 0.552
0.352MetThr: 0.352 ± 0.213
0.587MetVal: 0.587 ± 0.25
0.235MetTrp: 0.235 ± 0.156
1.173MetTyr: 1.173 ± 0.331
0.0MetXaa: 0.0 ± 0.0
Asn
3.871AsnAla: 3.871 ± 0.633
0.704AsnCys: 0.704 ± 0.245
2.346AsnAsp: 2.346 ± 0.533
5.63AsnGlu: 5.63 ± 0.804
5.513AsnPhe: 5.513 ± 0.67
4.223AsnGly: 4.223 ± 0.98
0.469AsnHis: 0.469 ± 0.194
6.452AsnIle: 6.452 ± 1.022
3.988AsnLys: 3.988 ± 0.744
8.328AsnLeu: 8.328 ± 1.381
1.877AsnMet: 1.877 ± 0.571
4.927AsnAsn: 4.927 ± 1.33
2.933AsnPro: 2.933 ± 0.498
2.815AsnGln: 2.815 ± 0.585
1.994AsnArg: 1.994 ± 0.471
4.809AsnSer: 4.809 ± 1.04
3.988AsnThr: 3.988 ± 0.809
4.575AsnVal: 4.575 ± 0.881
0.821AsnTrp: 0.821 ± 0.294
4.927AsnTyr: 4.927 ± 1.026
0.0AsnXaa: 0.0 ± 0.0
Pro
1.642ProAla: 1.642 ± 0.4
0.235ProCys: 0.235 ± 0.153
1.76ProAsp: 1.76 ± 0.391
1.76ProGlu: 1.76 ± 0.377
2.111ProPhe: 2.111 ± 0.421
0.938ProGly: 0.938 ± 0.311
0.469ProHis: 0.469 ± 0.232
3.05ProIle: 3.05 ± 0.64
1.994ProLys: 1.994 ± 0.594
3.284ProLeu: 3.284 ± 0.878
0.117ProMet: 0.117 ± 0.11
2.698ProAsn: 2.698 ± 0.56
1.525ProPro: 1.525 ± 0.478
1.642ProGln: 1.642 ± 0.462
1.056ProArg: 1.056 ± 0.403
2.229ProSer: 2.229 ± 0.512
1.877ProThr: 1.877 ± 0.484
2.463ProVal: 2.463 ± 0.681
0.352ProTrp: 0.352 ± 0.22
1.29ProTyr: 1.29 ± 0.286
0.0ProXaa: 0.0 ± 0.0
Gln
1.408GlnAla: 1.408 ± 0.355
0.352GlnCys: 0.352 ± 0.245
2.111GlnAsp: 2.111 ± 0.53
2.463GlnGlu: 2.463 ± 0.424
2.815GlnPhe: 2.815 ± 0.606
1.408GlnGly: 1.408 ± 0.388
0.235GlnHis: 0.235 ± 0.148
5.396GlnIle: 5.396 ± 0.58
4.809GlnLys: 4.809 ± 0.825
6.686GlnLeu: 6.686 ± 1.35
0.469GlnMet: 0.469 ± 0.238
3.871GlnAsn: 3.871 ± 0.614
0.938GlnPro: 0.938 ± 0.334
2.698GlnGln: 2.698 ± 0.552
0.821GlnArg: 0.821 ± 0.289
1.642GlnSer: 1.642 ± 0.364
2.229GlnThr: 2.229 ± 0.472
1.76GlnVal: 1.76 ± 0.432
0.235GlnTrp: 0.235 ± 0.158
3.05GlnTyr: 3.05 ± 0.626
0.0GlnXaa: 0.0 ± 0.0
Arg
0.704ArgAla: 0.704 ± 0.324
0.117ArgCys: 0.117 ± 0.109
0.821ArgAsp: 0.821 ± 0.27
2.229ArgGlu: 2.229 ± 0.574
1.29ArgPhe: 1.29 ± 0.402
0.821ArgGly: 0.821 ± 0.34
0.235ArgHis: 0.235 ± 0.161
3.402ArgIle: 3.402 ± 0.689
4.106ArgLys: 4.106 ± 0.615
2.111ArgLeu: 2.111 ± 0.45
0.704ArgMet: 0.704 ± 0.37
2.581ArgAsn: 2.581 ± 0.435
0.938ArgPro: 0.938 ± 0.308
1.056ArgGln: 1.056 ± 0.427
1.056ArgArg: 1.056 ± 0.299
1.642ArgSer: 1.642 ± 0.415
1.994ArgThr: 1.994 ± 0.352
1.173ArgVal: 1.173 ± 0.305
0.235ArgTrp: 0.235 ± 0.134
2.229ArgTyr: 2.229 ± 0.49
0.0ArgXaa: 0.0 ± 0.0
Ser
3.402SerAla: 3.402 ± 0.59
0.587SerCys: 0.587 ± 0.267
2.933SerAsp: 2.933 ± 0.63
3.519SerGlu: 3.519 ± 0.596
3.519SerPhe: 3.519 ± 0.817
3.284SerGly: 3.284 ± 0.51
0.704SerHis: 0.704 ± 0.287
6.334SerIle: 6.334 ± 0.969
3.05SerLys: 3.05 ± 0.646
4.457SerLeu: 4.457 ± 0.651
1.994SerMet: 1.994 ± 0.412
5.513SerAsn: 5.513 ± 0.903
1.877SerPro: 1.877 ± 0.492
3.988SerGln: 3.988 ± 0.691
2.229SerArg: 2.229 ± 0.44
4.457SerSer: 4.457 ± 1.121
2.815SerThr: 2.815 ± 0.703
2.815SerVal: 2.815 ± 0.584
0.469SerTrp: 0.469 ± 0.243
3.754SerTyr: 3.754 ± 0.812
0.0SerXaa: 0.0 ± 0.0
Thr
2.698ThrAla: 2.698 ± 0.615
0.235ThrCys: 0.235 ± 0.158
1.525ThrAsp: 1.525 ± 0.406
2.815ThrGlu: 2.815 ± 0.377
3.167ThrPhe: 3.167 ± 0.479
2.933ThrGly: 2.933 ± 0.704
0.117ThrHis: 0.117 ± 0.129
6.569ThrIle: 6.569 ± 0.809
3.871ThrLys: 3.871 ± 0.827
4.34ThrLeu: 4.34 ± 0.715
0.704ThrMet: 0.704 ± 0.247
3.636ThrAsn: 3.636 ± 0.724
2.346ThrPro: 2.346 ± 0.398
1.29ThrGln: 1.29 ± 0.347
1.29ThrArg: 1.29 ± 0.398
2.111ThrSer: 2.111 ± 0.567
3.284ThrThr: 3.284 ± 0.811
2.463ThrVal: 2.463 ± 0.785
0.587ThrTrp: 0.587 ± 0.295
2.815ThrTyr: 2.815 ± 0.555
0.0ThrXaa: 0.0 ± 0.0
Val
2.463ValAla: 2.463 ± 0.585
0.469ValCys: 0.469 ± 0.226
2.229ValAsp: 2.229 ± 0.568
3.402ValGlu: 3.402 ± 0.411
3.284ValPhe: 3.284 ± 0.522
2.698ValGly: 2.698 ± 0.503
0.704ValHis: 0.704 ± 0.3
3.519ValIle: 3.519 ± 0.552
5.044ValLys: 5.044 ± 0.945
4.809ValLeu: 4.809 ± 0.776
0.704ValMet: 0.704 ± 0.239
3.519ValAsn: 3.519 ± 0.582
2.346ValPro: 2.346 ± 0.577
2.229ValGln: 2.229 ± 0.485
2.229ValArg: 2.229 ± 0.477
3.636ValSer: 3.636 ± 0.595
2.698ValThr: 2.698 ± 0.639
2.111ValVal: 2.111 ± 0.666
0.235ValTrp: 0.235 ± 0.174
3.402ValTyr: 3.402 ± 0.8
0.0ValXaa: 0.0 ± 0.0
Trp
0.235TrpAla: 0.235 ± 0.157
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.117TrpGlu: 0.117 ± 0.119
0.587TrpPhe: 0.587 ± 0.22
0.235TrpGly: 0.235 ± 0.174
0.235TrpHis: 0.235 ± 0.153
0.938TrpIle: 0.938 ± 0.315
1.056TrpLys: 1.056 ± 0.298
1.173TrpLeu: 1.173 ± 0.371
0.235TrpMet: 0.235 ± 0.161
0.821TrpAsn: 0.821 ± 0.32
0.0TrpPro: 0.0 ± 0.0
0.469TrpGln: 0.469 ± 0.201
0.704TrpArg: 0.704 ± 0.247
0.235TrpSer: 0.235 ± 0.156
0.352TrpThr: 0.352 ± 0.189
0.587TrpVal: 0.587 ± 0.279
0.0TrpTrp: 0.0 ± 0.0
0.235TrpTyr: 0.235 ± 0.155
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.636TyrAla: 3.636 ± 0.66
0.704TyrCys: 0.704 ± 0.259
2.933TyrAsp: 2.933 ± 0.595
2.815TyrGlu: 2.815 ± 0.615
3.167TyrPhe: 3.167 ± 0.628
2.815TyrGly: 2.815 ± 0.677
0.821TyrHis: 0.821 ± 0.395
6.921TyrIle: 6.921 ± 1.025
3.636TyrLys: 3.636 ± 0.691
5.865TyrLeu: 5.865 ± 0.815
1.29TyrMet: 1.29 ± 0.308
3.754TyrAsn: 3.754 ± 0.571
2.933TyrPro: 2.933 ± 0.442
3.988TyrGln: 3.988 ± 0.645
1.173TyrArg: 1.173 ± 0.484
3.402TyrSer: 3.402 ± 0.556
3.636TyrThr: 3.636 ± 0.892
3.05TyrVal: 3.05 ± 0.626
0.469TyrTrp: 0.469 ± 0.205
4.106TyrTyr: 4.106 ± 0.67
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 43 proteins (8526 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski