Amino acid dipepetide frequency for Fall chinook aquareovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.665AlaAla: 10.665 ± 1.927
1.2AlaCys: 1.2 ± 0.479
3.333AlaAsp: 3.333 ± 0.576
3.066AlaGlu: 3.066 ± 0.453
4.533AlaPhe: 4.533 ± 0.705
5.599AlaGly: 5.599 ± 0.908
3.2AlaHis: 3.2 ± 0.542
5.333AlaIle: 5.333 ± 0.591
2.0AlaLys: 2.0 ± 0.437
8.266AlaLeu: 8.266 ± 0.967
3.333AlaMet: 3.333 ± 1.051
5.333AlaAsn: 5.333 ± 0.862
4.666AlaPro: 4.666 ± 0.797
3.866AlaGln: 3.866 ± 1.047
5.066AlaArg: 5.066 ± 0.679
8.532AlaSer: 8.532 ± 1.287
8.132AlaThr: 8.132 ± 0.867
7.599AlaVal: 7.599 ± 1.023
1.733AlaTrp: 1.733 ± 0.549
2.533AlaTyr: 2.533 ± 0.942
0.0AlaXaa: 0.0 ± 0.0
Cys
1.2CysAla: 1.2 ± 0.376
0.8CysCys: 0.8 ± 0.92
0.933CysAsp: 0.933 ± 0.301
0.667CysGlu: 0.667 ± 0.342
0.667CysPhe: 0.667 ± 0.281
1.2CysGly: 1.2 ± 0.345
0.8CysHis: 0.8 ± 0.358
0.8CysIle: 0.8 ± 0.363
0.4CysLys: 0.4 ± 0.24
0.667CysLeu: 0.667 ± 0.229
0.133CysMet: 0.133 ± 0.142
0.4CysAsn: 0.4 ± 0.222
0.933CysPro: 0.933 ± 0.307
0.8CysGln: 0.8 ± 0.254
0.667CysArg: 0.667 ± 0.252
0.267CysSer: 0.267 ± 0.214
0.533CysThr: 0.533 ± 0.257
0.933CysVal: 0.933 ± 0.439
0.0CysTrp: 0.0 ± 0.0
0.133CysTyr: 0.133 ± 0.123
0.0CysXaa: 0.0 ± 0.0
Asp
6.133AspAla: 6.133 ± 0.848
0.533AspCys: 0.533 ± 0.314
2.8AspAsp: 2.8 ± 0.601
1.466AspGlu: 1.466 ± 0.494
1.733AspPhe: 1.733 ± 0.334
3.999AspGly: 3.999 ± 0.497
1.067AspHis: 1.067 ± 0.384
3.6AspIle: 3.6 ± 0.754
0.933AspLys: 0.933 ± 0.282
5.866AspLeu: 5.866 ± 0.74
1.466AspMet: 1.466 ± 0.466
1.733AspAsn: 1.733 ± 0.574
4.799AspPro: 4.799 ± 0.924
1.333AspGln: 1.333 ± 0.364
2.533AspArg: 2.533 ± 0.721
3.2AspSer: 3.2 ± 0.71
2.266AspThr: 2.266 ± 0.281
5.066AspVal: 5.066 ± 1.057
0.933AspTrp: 0.933 ± 0.323
1.733AspTyr: 1.733 ± 0.623
0.0AspXaa: 0.0 ± 0.0
Glu
2.133GluAla: 2.133 ± 0.534
0.667GluCys: 0.667 ± 0.593
1.2GluAsp: 1.2 ± 0.341
1.067GluGlu: 1.067 ± 0.252
1.466GluPhe: 1.466 ± 0.513
1.333GluGly: 1.333 ± 0.218
0.933GluHis: 0.933 ± 0.285
0.933GluIle: 0.933 ± 0.326
0.667GluLys: 0.667 ± 0.605
3.999GluLeu: 3.999 ± 0.766
1.333GluMet: 1.333 ± 0.458
1.2GluAsn: 1.2 ± 0.473
1.733GluPro: 1.733 ± 0.25
0.8GluGln: 0.8 ± 0.384
2.266GluArg: 2.266 ± 0.628
2.933GluSer: 2.933 ± 0.651
2.266GluThr: 2.266 ± 0.414
2.8GluVal: 2.8 ± 0.608
0.8GluTrp: 0.8 ± 0.354
1.067GluTyr: 1.067 ± 0.378
0.0GluXaa: 0.0 ± 0.0
Phe
3.733PheAla: 3.733 ± 0.642
0.0PheCys: 0.0 ± 0.0
2.533PheAsp: 2.533 ± 0.469
0.933PheGlu: 0.933 ± 0.436
0.667PhePhe: 0.667 ± 0.145
1.866PheGly: 1.866 ± 0.392
0.667PheHis: 0.667 ± 0.253
2.133PheIle: 2.133 ± 0.493
1.733PheLys: 1.733 ± 0.496
3.6PheLeu: 3.6 ± 0.571
1.466PheMet: 1.466 ± 0.409
1.466PheAsn: 1.466 ± 0.358
2.933PhePro: 2.933 ± 0.635
0.8PheGln: 0.8 ± 0.272
0.8PheArg: 0.8 ± 0.315
3.466PheSer: 3.466 ± 0.282
2.533PheThr: 2.533 ± 0.521
1.733PheVal: 1.733 ± 0.598
0.533PheTrp: 0.533 ± 0.324
1.2PheTyr: 1.2 ± 0.294
0.0PheXaa: 0.0 ± 0.0
Gly
3.6GlyAla: 3.6 ± 0.64
0.933GlyCys: 0.933 ± 0.439
3.6GlyAsp: 3.6 ± 0.762
1.466GlyGlu: 1.466 ± 0.425
2.266GlyPhe: 2.266 ± 0.539
2.933GlyGly: 2.933 ± 0.458
1.067GlyHis: 1.067 ± 0.286
3.2GlyIle: 3.2 ± 0.775
2.4GlyLys: 2.4 ± 0.834
5.733GlyLeu: 5.733 ± 0.756
2.266GlyMet: 2.266 ± 0.572
2.666GlyAsn: 2.666 ± 0.643
3.6GlyPro: 3.6 ± 0.664
2.133GlyGln: 2.133 ± 0.482
3.066GlyArg: 3.066 ± 0.549
5.199GlySer: 5.199 ± 0.474
3.733GlyThr: 3.733 ± 0.565
4.399GlyVal: 4.399 ± 0.582
0.8GlyTrp: 0.8 ± 0.274
1.733GlyTyr: 1.733 ± 0.396
0.0GlyXaa: 0.0 ± 0.0
His
2.666HisAla: 2.666 ± 0.416
0.133HisCys: 0.133 ± 0.123
1.733HisAsp: 1.733 ± 0.355
0.267HisGlu: 0.267 ± 0.189
0.667HisPhe: 0.667 ± 0.337
1.733HisGly: 1.733 ± 0.484
0.8HisHis: 0.8 ± 0.355
1.6HisIle: 1.6 ± 0.431
0.667HisLys: 0.667 ± 0.493
3.466HisLeu: 3.466 ± 0.65
0.4HisMet: 0.4 ± 0.231
0.533HisAsn: 0.533 ± 0.209
2.666HisPro: 2.666 ± 0.608
0.933HisGln: 0.933 ± 0.378
1.067HisArg: 1.067 ± 0.34
2.266HisSer: 2.266 ± 0.451
1.466HisThr: 1.466 ± 0.58
2.666HisVal: 2.666 ± 0.382
0.4HisTrp: 0.4 ± 0.211
0.933HisTyr: 0.933 ± 0.319
0.0HisXaa: 0.0 ± 0.0
Ile
4.666IleAla: 4.666 ± 0.98
0.267IleCys: 0.267 ± 0.147
4.133IleAsp: 4.133 ± 0.697
1.333IleGlu: 1.333 ± 0.346
1.2IlePhe: 1.2 ± 0.447
3.6IleGly: 3.6 ± 0.809
1.466IleHis: 1.466 ± 0.411
3.333IleIle: 3.333 ± 0.426
1.466IleLys: 1.466 ± 0.326
3.333IleLeu: 3.333 ± 0.618
1.333IleMet: 1.333 ± 0.35
3.066IleAsn: 3.066 ± 0.319
4.399IlePro: 4.399 ± 0.718
2.8IleGln: 2.8 ± 0.433
2.266IleArg: 2.266 ± 0.631
4.799IleSer: 4.799 ± 0.719
4.799IleThr: 4.799 ± 0.897
3.866IleVal: 3.866 ± 0.575
0.667IleTrp: 0.667 ± 0.199
1.067IleTyr: 1.067 ± 0.231
0.0IleXaa: 0.0 ± 0.0
Lys
2.0LysAla: 2.0 ± 0.437
0.533LysCys: 0.533 ± 0.28
1.466LysAsp: 1.466 ± 0.307
0.4LysGlu: 0.4 ± 0.215
0.667LysPhe: 0.667 ± 0.222
1.6LysGly: 1.6 ± 0.498
0.533LysHis: 0.533 ± 0.214
0.933LysIle: 0.933 ± 0.297
0.4LysLys: 0.4 ± 0.255
2.0LysLeu: 2.0 ± 0.516
0.667LysMet: 0.667 ± 0.267
0.933LysAsn: 0.933 ± 0.481
1.733LysPro: 1.733 ± 0.479
0.933LysGln: 0.933 ± 0.26
1.6LysArg: 1.6 ± 0.458
2.266LysSer: 2.266 ± 0.604
1.333LysThr: 1.333 ± 0.431
2.266LysVal: 2.266 ± 0.805
0.533LysTrp: 0.533 ± 0.24
0.4LysTyr: 0.4 ± 0.183
0.0LysXaa: 0.0 ± 0.0
Leu
9.199LeuAla: 9.199 ± 0.893
1.466LeuCys: 1.466 ± 0.571
5.466LeuAsp: 5.466 ± 0.992
3.733LeuGlu: 3.733 ± 0.717
3.6LeuPhe: 3.6 ± 0.679
5.466LeuGly: 5.466 ± 0.843
2.533LeuHis: 2.533 ± 0.504
4.799LeuIle: 4.799 ± 0.508
2.8LeuLys: 2.8 ± 0.57
9.332LeuLeu: 9.332 ± 1.056
2.4LeuMet: 2.4 ± 0.716
4.399LeuAsn: 4.399 ± 0.732
6.532LeuPro: 6.532 ± 0.97
4.133LeuGln: 4.133 ± 0.428
6.266LeuArg: 6.266 ± 0.664
8.932LeuSer: 8.932 ± 0.733
7.999LeuThr: 7.999 ± 1.423
3.999LeuVal: 3.999 ± 0.837
1.333LeuTrp: 1.333 ± 0.52
2.8LeuTyr: 2.8 ± 0.543
0.0LeuXaa: 0.0 ± 0.0
Met
3.2MetAla: 3.2 ± 0.553
0.267MetCys: 0.267 ± 0.142
1.6MetAsp: 1.6 ± 0.442
2.0MetGlu: 2.0 ± 0.379
0.8MetPhe: 0.8 ± 0.29
1.2MetGly: 1.2 ± 0.285
0.8MetHis: 0.8 ± 0.296
1.6MetIle: 1.6 ± 0.574
0.667MetLys: 0.667 ± 0.26
2.666MetLeu: 2.666 ± 0.709
0.533MetMet: 0.533 ± 0.241
1.866MetAsn: 1.866 ± 0.567
1.333MetPro: 1.333 ± 0.454
0.8MetGln: 0.8 ± 0.311
0.667MetArg: 0.667 ± 0.21
2.933MetSer: 2.933 ± 0.73
1.866MetThr: 1.866 ± 0.455
2.266MetVal: 2.266 ± 0.557
0.4MetTrp: 0.4 ± 0.215
0.667MetTyr: 0.667 ± 0.494
0.0MetXaa: 0.0 ± 0.0
Asn
5.599AsnAla: 5.599 ± 0.932
0.4AsnCys: 0.4 ± 0.177
1.866AsnAsp: 1.866 ± 0.352
0.933AsnGlu: 0.933 ± 0.239
1.466AsnPhe: 1.466 ± 0.524
2.133AsnGly: 2.133 ± 0.501
1.2AsnHis: 1.2 ± 0.368
1.733AsnIle: 1.733 ± 0.353
0.8AsnLys: 0.8 ± 0.302
4.399AsnLeu: 4.399 ± 0.721
0.667AsnMet: 0.667 ± 0.24
0.933AsnAsn: 0.933 ± 0.274
3.466AsnPro: 3.466 ± 0.597
2.266AsnGln: 2.266 ± 0.72
3.2AsnArg: 3.2 ± 0.609
1.866AsnSer: 1.866 ± 0.626
3.2AsnThr: 3.2 ± 0.746
3.2AsnVal: 3.2 ± 0.531
0.4AsnTrp: 0.4 ± 0.207
1.6AsnTyr: 1.6 ± 0.488
0.0AsnXaa: 0.0 ± 0.0
Pro
8.266ProAla: 8.266 ± 0.986
0.4ProCys: 0.4 ± 0.34
4.533ProAsp: 4.533 ± 0.657
2.4ProGlu: 2.4 ± 0.58
2.8ProPhe: 2.8 ± 0.661
3.466ProGly: 3.466 ± 0.707
1.466ProHis: 1.466 ± 0.661
4.933ProIle: 4.933 ± 0.501
0.8ProLys: 0.8 ± 0.383
9.065ProLeu: 9.065 ± 1.095
1.6ProMet: 1.6 ± 0.443
3.2ProAsn: 3.2 ± 0.42
5.866ProPro: 5.866 ± 0.759
2.133ProGln: 2.133 ± 0.56
3.6ProArg: 3.6 ± 0.736
7.066ProSer: 7.066 ± 0.453
7.066ProThr: 7.066 ± 0.707
4.533ProVal: 4.533 ± 0.588
1.466ProTrp: 1.466 ± 0.36
2.0ProTyr: 2.0 ± 0.475
0.0ProXaa: 0.0 ± 0.0
Gln
4.666GlnAla: 4.666 ± 0.732
0.4GlnCys: 0.4 ± 0.267
2.0GlnAsp: 2.0 ± 0.581
0.667GlnGlu: 0.667 ± 0.255
1.333GlnPhe: 1.333 ± 0.329
1.6GlnGly: 1.6 ± 0.403
0.933GlnHis: 0.933 ± 0.389
1.733GlnIle: 1.733 ± 0.403
0.4GlnLys: 0.4 ± 0.205
5.199GlnLeu: 5.199 ± 0.768
0.8GlnMet: 0.8 ± 0.371
1.2GlnAsn: 1.2 ± 0.335
2.933GlnPro: 2.933 ± 0.754
1.466GlnGln: 1.466 ± 0.412
1.866GlnArg: 1.866 ± 0.405
2.4GlnSer: 2.4 ± 0.353
2.533GlnThr: 2.533 ± 0.514
3.466GlnVal: 3.466 ± 0.594
0.4GlnTrp: 0.4 ± 0.215
1.6GlnTyr: 1.6 ± 0.459
0.0GlnXaa: 0.0 ± 0.0
Arg
5.199ArgAla: 5.199 ± 0.531
0.933ArgCys: 0.933 ± 0.417
2.8ArgAsp: 2.8 ± 0.832
1.866ArgGlu: 1.866 ± 0.469
0.933ArgPhe: 0.933 ± 0.258
3.2ArgGly: 3.2 ± 0.58
1.6ArgHis: 1.6 ± 0.543
3.466ArgIle: 3.466 ± 0.544
0.667ArgLys: 0.667 ± 0.251
6.133ArgLeu: 6.133 ± 0.824
1.733ArgMet: 1.733 ± 0.725
1.466ArgAsn: 1.466 ± 0.449
3.733ArgPro: 3.733 ± 0.646
2.133ArgGln: 2.133 ± 0.619
3.333ArgArg: 3.333 ± 0.704
4.399ArgSer: 4.399 ± 1.278
2.8ArgThr: 2.8 ± 0.519
3.733ArgVal: 3.733 ± 0.751
1.2ArgTrp: 1.2 ± 0.296
1.733ArgTyr: 1.733 ± 0.438
0.0ArgXaa: 0.0 ± 0.0
Ser
8.132SerAla: 8.132 ± 1.07
0.8SerCys: 0.8 ± 0.517
3.999SerAsp: 3.999 ± 0.711
2.666SerGlu: 2.666 ± 0.718
3.066SerPhe: 3.066 ± 0.471
5.333SerGly: 5.333 ± 0.912
2.133SerHis: 2.133 ± 0.675
4.133SerIle: 4.133 ± 0.568
2.0SerLys: 2.0 ± 0.507
6.932SerLeu: 6.932 ± 0.895
1.466SerMet: 1.466 ± 0.432
2.8SerAsn: 2.8 ± 0.619
6.932SerPro: 6.932 ± 0.883
3.333SerGln: 3.333 ± 0.624
5.466SerArg: 5.466 ± 0.938
8.132SerSer: 8.132 ± 1.307
6.399SerThr: 6.399 ± 0.452
7.066SerVal: 7.066 ± 0.959
1.2SerTrp: 1.2 ± 0.346
2.4SerTyr: 2.4 ± 0.573
0.0SerXaa: 0.0 ± 0.0
Thr
6.666ThrAla: 6.666 ± 1.231
1.2ThrCys: 1.2 ± 0.432
3.066ThrAsp: 3.066 ± 0.443
2.533ThrGlu: 2.533 ± 0.39
2.533ThrPhe: 2.533 ± 0.483
4.533ThrGly: 4.533 ± 0.97
2.933ThrHis: 2.933 ± 0.768
2.666ThrIle: 2.666 ± 0.698
0.933ThrLys: 0.933 ± 0.24
6.399ThrLeu: 6.399 ± 0.679
2.266ThrMet: 2.266 ± 0.424
3.466ThrAsn: 3.466 ± 0.794
6.399ThrPro: 6.399 ± 0.967
2.4ThrGln: 2.4 ± 0.518
2.8ThrArg: 2.8 ± 0.424
6.266ThrSer: 6.266 ± 1.036
6.266ThrThr: 6.266 ± 1.093
6.133ThrVal: 6.133 ± 0.645
0.933ThrTrp: 0.933 ± 0.33
2.666ThrTyr: 2.666 ± 0.53
0.0ThrXaa: 0.0 ± 0.0
Val
6.532ValAla: 6.532 ± 0.711
1.466ValCys: 1.466 ± 0.334
3.2ValAsp: 3.2 ± 0.769
2.8ValGlu: 2.8 ± 0.563
2.4ValPhe: 2.4 ± 0.804
3.2ValGly: 3.2 ± 0.628
2.0ValHis: 2.0 ± 0.358
3.866ValIle: 3.866 ± 0.552
1.333ValLys: 1.333 ± 0.311
5.733ValLeu: 5.733 ± 1.207
3.066ValMet: 3.066 ± 0.429
3.333ValAsn: 3.333 ± 0.757
7.732ValPro: 7.732 ± 1.012
2.533ValGln: 2.533 ± 0.612
3.866ValArg: 3.866 ± 0.647
6.399ValSer: 6.399 ± 1.187
5.599ValThr: 5.599 ± 0.826
4.399ValVal: 4.399 ± 0.474
0.8ValTrp: 0.8 ± 0.211
2.4ValTyr: 2.4 ± 0.347
0.0ValXaa: 0.0 ± 0.0
Trp
1.2TrpAla: 1.2 ± 0.32
0.133TrpCys: 0.133 ± 0.123
0.667TrpAsp: 0.667 ± 0.268
0.667TrpGlu: 0.667 ± 0.384
1.067TrpPhe: 1.067 ± 0.314
0.4TrpGly: 0.4 ± 0.207
0.4TrpHis: 0.4 ± 0.219
0.933TrpIle: 0.933 ± 0.453
0.667TrpLys: 0.667 ± 0.145
1.866TrpLeu: 1.866 ± 0.375
0.533TrpMet: 0.533 ± 0.364
0.533TrpAsn: 0.533 ± 0.279
1.466TrpPro: 1.466 ± 0.522
0.667TrpGln: 0.667 ± 0.307
0.933TrpArg: 0.933 ± 0.41
1.067TrpSer: 1.067 ± 0.34
0.933TrpThr: 0.933 ± 0.324
0.4TrpVal: 0.4 ± 0.176
0.533TrpTrp: 0.533 ± 0.35
0.267TrpTyr: 0.267 ± 0.181
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.533TyrAla: 2.533 ± 0.753
0.4TyrCys: 0.4 ± 0.211
2.266TyrAsp: 2.266 ± 0.457
0.667TyrGlu: 0.667 ± 0.268
0.933TyrPhe: 0.933 ± 0.349
2.4TyrGly: 2.4 ± 0.426
0.533TyrHis: 0.533 ± 0.242
2.133TyrIle: 2.133 ± 0.355
1.466TyrLys: 1.466 ± 0.473
2.533TyrLeu: 2.533 ± 0.566
0.533TyrMet: 0.533 ± 0.29
0.8TyrAsn: 0.8 ± 0.272
2.8TyrPro: 2.8 ± 0.551
1.333TyrGln: 1.333 ± 0.411
1.733TyrArg: 1.733 ± 0.448
2.0TyrSer: 2.0 ± 0.312
1.333TyrThr: 1.333 ± 0.533
2.133TyrVal: 2.133 ± 0.533
0.267TyrTrp: 0.267 ± 0.242
0.4TyrTyr: 0.4 ± 0.219
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (7502 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski