Amino acid dipepetide frequency for Pseudonaja textilis (Eastern brown snake)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.641AlaAla: 5.641 ± 0.033	1.319AlaCys: 1.319 ± 0.012	2.787AlaAsp: 2.787 ± 0.015	4.424AlaGlu: 4.424 ± 0.023	2.615AlaPhe: 2.615 ± 0.015	3.905AlaGly: 3.905 ± 0.023	1.366AlaHis: 1.366 ± 0.01	3.164AlaIle: 3.164 ± 0.014	3.636AlaLys: 3.636 ± 0.025	6.444AlaLeu: 6.444 ± 0.027	1.485AlaMet: 1.485 ± 0.01	2.249AlaAsn: 2.249 ± 0.011	2.933AlaPro: 2.933 ± 0.019	2.699AlaGln: 2.699 ± 0.019	2.957AlaArg: 2.957 ± 0.017	5.163AlaSer: 5.163 ± 0.021	3.386AlaThr: 3.386 ± 0.017	4.403AlaVal: 4.403 ± 0.017	0.72AlaTrp: 0.72 ± 0.007	1.581AlaTyr: 1.581 ± 0.009	0.0AlaXaa: 0.0 ± 0.0
Cys	1.172CysAla: 1.172 ± 0.011	0.638CysCys: 0.638 ± 0.008	1.034CysAsp: 1.034 ± 0.013	1.273CysGlu: 1.273 ± 0.015	1.023CysPhe: 1.023 ± 0.009	1.606CysGly: 1.606 ± 0.022	0.689CysHis: 0.689 ± 0.007	1.238CysIle: 1.238 ± 0.012	1.301CysLys: 1.301 ± 0.013	2.365CysLeu: 2.365 ± 0.015	0.482CysMet: 0.482 ± 0.007	0.947CysAsn: 0.947 ± 0.008	1.301CysPro: 1.301 ± 0.016	1.116CysGln: 1.116 ± 0.014	1.213CysArg: 1.213 ± 0.01	2.009CysSer: 2.009 ± 0.016	1.169CysThr: 1.169 ± 0.012	1.287CysVal: 1.287 ± 0.012	0.29CysTrp: 0.29 ± 0.004	0.68CysTyr: 0.68 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	2.723AspAla: 2.723 ± 0.015	1.102AspCys: 1.102 ± 0.012	2.607AspAsp: 2.607 ± 0.016	3.44AspGlu: 3.44 ± 0.018	2.224AspPhe: 2.224 ± 0.011	3.111AspGly: 3.111 ± 0.024	1.155AspHis: 1.155 ± 0.008	2.96AspIle: 2.96 ± 0.014	2.666AspLys: 2.666 ± 0.015	5.082AspLeu: 5.082 ± 0.019	1.134AspMet: 1.134 ± 0.009	1.965AspAsn: 1.965 ± 0.014	2.686AspPro: 2.686 ± 0.013	1.867AspGln: 1.867 ± 0.011	2.288AspArg: 2.288 ± 0.013	3.943AspSer: 3.943 ± 0.018	2.366AspThr: 2.366 ± 0.013	2.972AspVal: 2.972 ± 0.016	0.635AspTrp: 0.635 ± 0.006	1.624AspTyr: 1.624 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	4.732GluAla: 4.732 ± 0.024	1.442GluCys: 1.442 ± 0.022	4.252GluAsp: 4.252 ± 0.02	7.651GluGlu: 7.651 ± 0.05	2.165GluPhe: 2.165 ± 0.014	3.957GluGly: 3.957 ± 0.019	1.491GluHis: 1.491 ± 0.012	3.768GluIle: 3.768 ± 0.022	5.795GluLys: 5.795 ± 0.035	6.379GluLeu: 6.379 ± 0.034	1.823GluMet: 1.823 ± 0.014	3.451GluAsn: 3.451 ± 0.019	2.584GluPro: 2.584 ± 0.015	3.11GluGln: 3.11 ± 0.022	3.793GluArg: 3.793 ± 0.021	4.348GluSer: 4.348 ± 0.021	3.479GluThr: 3.479 ± 0.015	4.113GluVal: 4.113 ± 0.018	0.731GluTrp: 0.731 ± 0.007	1.766GluTyr: 1.766 ± 0.01	0.001GluXaa: 0.001 ± 0.0
Phe	2.182PheAla: 2.182 ± 0.013	1.089PheCys: 1.089 ± 0.008	1.802PheAsp: 1.802 ± 0.013	2.168PheGlu: 2.168 ± 0.014	1.99PhePhe: 1.99 ± 0.015	2.289PheGly: 2.289 ± 0.016	1.172PheHis: 1.172 ± 0.008	2.211PheIle: 2.211 ± 0.016	2.036PheLys: 2.036 ± 0.012	4.667PheLeu: 4.667 ± 0.024	0.851PheMet: 0.851 ± 0.008	1.602PheAsn: 1.602 ± 0.01	2.135PhePro: 2.135 ± 0.012	1.948PheGln: 1.948 ± 0.011	1.989PheArg: 1.989 ± 0.012	3.742PheSer: 3.742 ± 0.019	2.174PheThr: 2.174 ± 0.014	2.304PheVal: 2.304 ± 0.013	0.541PheTrp: 0.541 ± 0.006	1.395PheTyr: 1.395 ± 0.012	0.001PheXaa: 0.001 ± 0.0
Gly	3.465GlyAla: 3.465 ± 0.022	1.219GlyCys: 1.219 ± 0.011	2.875GlyAsp: 2.875 ± 0.017	3.895GlyGlu: 3.895 ± 0.02	2.471GlyPhe: 2.471 ± 0.016	4.474GlyGly: 4.474 ± 0.034	1.569GlyHis: 1.569 ± 0.012	3.199GlyIle: 3.199 ± 0.017	4.093GlyLys: 4.093 ± 0.021	5.3GlyLeu: 5.3 ± 0.024	1.327GlyMet: 1.327 ± 0.01	2.62GlyAsn: 2.62 ± 0.018	2.837GlyPro: 2.837 ± 0.027	2.537GlyGln: 2.537 ± 0.014	3.3GlyArg: 3.3 ± 0.022	5.088GlySer: 5.088 ± 0.027	3.33GlyThr: 3.33 ± 0.019	3.169GlyVal: 3.169 ± 0.017	0.809GlyTrp: 0.809 ± 0.009	1.842GlyTyr: 1.842 ± 0.017	0.002GlyXaa: 0.002 ± 0.0
His	1.297HisAla: 1.297 ± 0.01	0.75HisCys: 0.75 ± 0.008	0.923HisAsp: 0.923 ± 0.007	1.392HisGlu: 1.392 ± 0.011	1.22HisPhe: 1.22 ± 0.009	1.463HisGly: 1.463 ± 0.011	0.886HisHis: 0.886 ± 0.01	1.446HisIle: 1.446 ± 0.011	1.452HisLys: 1.452 ± 0.011	3.013HisLeu: 3.013 ± 0.015	0.567HisMet: 0.567 ± 0.006	1.047HisAsn: 1.047 ± 0.009	1.538HisPro: 1.538 ± 0.011	1.305HisGln: 1.305 ± 0.012	1.434HisArg: 1.434 ± 0.009	2.226HisSer: 2.226 ± 0.013	1.45HisThr: 1.45 ± 0.013	1.432HisVal: 1.432 ± 0.01	0.349HisTrp: 0.349 ± 0.006	0.898HisTyr: 0.898 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.037IleAla: 3.037 ± 0.017	1.361IleCys: 1.361 ± 0.013	2.401IleAsp: 2.401 ± 0.015	2.998IleGlu: 2.998 ± 0.018	2.353IlePhe: 2.353 ± 0.017	2.618IleGly: 2.618 ± 0.014	1.588IleHis: 1.588 ± 0.015	2.995IleIle: 2.995 ± 0.016	3.149IleLys: 3.149 ± 0.018	5.484IleLeu: 5.484 ± 0.026	1.17IleMet: 1.17 ± 0.009	2.351IleAsn: 2.351 ± 0.016	2.897IlePro: 2.897 ± 0.016	2.709IleGln: 2.709 ± 0.016	2.57IleArg: 2.57 ± 0.012	4.363IleSer: 4.363 ± 0.018	2.943IleThr: 2.943 ± 0.017	2.992IleVal: 2.992 ± 0.016	0.621IleTrp: 0.621 ± 0.007	1.729IleTyr: 1.729 ± 0.012	0.001IleXaa: 0.001 ± 0.0
Lys	3.996LysAla: 3.996 ± 0.023	1.328LysCys: 1.328 ± 0.015	3.365LysAsp: 3.365 ± 0.017	5.537LysGlu: 5.537 ± 0.033	1.932LysPhe: 1.932 ± 0.013	3.362LysGly: 3.362 ± 0.019	1.574LysHis: 1.574 ± 0.011	3.383LysIle: 3.383 ± 0.018	5.066LysLys: 5.066 ± 0.031	5.736LysLeu: 5.736 ± 0.03	1.608LysMet: 1.608 ± 0.011	2.869LysAsn: 2.869 ± 0.016	3.022LysPro: 3.022 ± 0.02	2.922LysGln: 2.922 ± 0.019	3.464LysArg: 3.464 ± 0.018	4.213LysSer: 4.213 ± 0.022	3.299LysThr: 3.299 ± 0.018	3.703LysVal: 3.703 ± 0.018	0.696LysTrp: 0.696 ± 0.007	1.867LysTyr: 1.867 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	6.427LeuAla: 6.427 ± 0.026	2.256LeuCys: 2.256 ± 0.015	4.88LeuAsp: 4.88 ± 0.02	7.21LeuGlu: 7.21 ± 0.041	3.86LeuPhe: 3.86 ± 0.019	5.377LeuGly: 5.377 ± 0.022	2.908LeuHis: 2.908 ± 0.016	4.585LeuIle: 4.585 ± 0.024	6.382LeuLys: 6.382 ± 0.03	10.892LeuLeu: 10.892 ± 0.042	2.147LeuMet: 2.147 ± 0.013	4.148LeuAsn: 4.148 ± 0.019	5.638LeuPro: 5.638 ± 0.024	5.832LeuGln: 5.832 ± 0.034	5.359LeuArg: 5.359 ± 0.022	8.095LeuSer: 8.095 ± 0.026	4.996LeuThr: 4.996 ± 0.017	5.456LeuVal: 5.456 ± 0.024	1.137LeuTrp: 1.137 ± 0.009	2.783LeuTyr: 2.783 ± 0.016	0.002LeuXaa: 0.002 ± 0.0
Met	1.787MetAla: 1.787 ± 0.011	0.428MetCys: 0.428 ± 0.006	1.338MetAsp: 1.338 ± 0.009	2.014MetGlu: 2.014 ± 0.012	0.861MetPhe: 0.861 ± 0.008	1.259MetGly: 1.259 ± 0.01	0.523MetHis: 0.523 ± 0.005	1.035MetIle: 1.035 ± 0.009	1.601MetLys: 1.601 ± 0.012	2.108MetLeu: 2.108 ± 0.013	0.587MetMet: 0.587 ± 0.007	1.033MetAsn: 1.033 ± 0.008	1.076MetPro: 1.076 ± 0.009	1.021MetGln: 1.021 ± 0.009	1.037MetArg: 1.037 ± 0.008	1.531MetSer: 1.531 ± 0.011	1.157MetThr: 1.157 ± 0.008	1.478MetVal: 1.478 ± 0.009	0.252MetTrp: 0.252 ± 0.004	0.629MetTyr: 0.629 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.309AsnAla: 2.309 ± 0.014	1.025AsnCys: 1.025 ± 0.01	1.753AsnAsp: 1.753 ± 0.013	2.597AsnGlu: 2.597 ± 0.017	1.743AsnPhe: 1.743 ± 0.012	2.746AsnGly: 2.746 ± 0.02	1.075AsnHis: 1.075 ± 0.009	2.728AsnIle: 2.728 ± 0.015	2.587AsnLys: 2.587 ± 0.016	4.301AsnLeu: 4.301 ± 0.017	1.049AsnMet: 1.049 ± 0.007	1.941AsnAsn: 1.941 ± 0.013	2.342AsnPro: 2.342 ± 0.013	1.903AsnGln: 1.903 ± 0.012	2.045AsnArg: 2.045 ± 0.012	3.547AsnSer: 3.547 ± 0.021	2.193AsnThr: 2.193 ± 0.013	2.485AsnVal: 2.485 ± 0.013	0.536AsnTrp: 0.536 ± 0.005	1.36AsnTyr: 1.36 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	3.596ProAla: 3.596 ± 0.023	1.058ProCys: 1.058 ± 0.012	2.564ProAsp: 2.564 ± 0.017	3.821ProGlu: 3.821 ± 0.016	2.093ProPhe: 2.093 ± 0.013	3.653ProGly: 3.653 ± 0.027	1.315ProHis: 1.315 ± 0.009	2.157ProIle: 2.157 ± 0.012	2.782ProLys: 2.782 ± 0.018	4.991ProLeu: 4.991 ± 0.023	0.968ProMet: 0.968 ± 0.008	1.99ProAsn: 1.99 ± 0.013	4.766ProPro: 4.766 ± 0.043	2.392ProGln: 2.392 ± 0.014	2.488ProArg: 2.488 ± 0.017	5.056ProSer: 5.056 ± 0.025	2.68ProThr: 2.68 ± 0.016	3.449ProVal: 3.449 ± 0.017	0.594ProTrp: 0.594 ± 0.006	1.551ProTyr: 1.551 ± 0.015	0.002ProXaa: 0.002 ± 0.0
Gln	3.096GlnAla: 3.096 ± 0.019	1.019GlnCys: 1.019 ± 0.012	2.22GlnAsp: 2.22 ± 0.012	3.731GlnGlu: 3.731 ± 0.024	1.557GlnPhe: 1.557 ± 0.012	2.495GlnGly: 2.495 ± 0.016	1.291GlnHis: 1.291 ± 0.011	2.377GlnIle: 2.377 ± 0.015	3.143GlnLys: 3.143 ± 0.021	4.767GlnLeu: 4.767 ± 0.027	1.179GlnMet: 1.179 ± 0.009	2.206GlnAsn: 2.206 ± 0.011	2.389GlnPro: 2.389 ± 0.018	3.051GlnGln: 3.051 ± 0.032	2.697GlnArg: 2.697 ± 0.017	3.107GlnSer: 3.107 ± 0.017	2.296GlnThr: 2.296 ± 0.013	2.775GlnVal: 2.775 ± 0.014	0.563GlnTrp: 0.563 ± 0.006	1.277GlnTyr: 1.277 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	2.967ArgAla: 2.967 ± 0.015	1.164ArgCys: 1.164 ± 0.012	2.497ArgAsp: 2.497 ± 0.016	3.548ArgGlu: 3.548 ± 0.018	1.954ArgPhe: 1.954 ± 0.011	2.924ArgGly: 2.924 ± 0.019	1.411ArgHis: 1.411 ± 0.012	2.8ArgIle: 2.8 ± 0.015	3.727ArgLys: 3.727 ± 0.02	5.006ArgLeu: 5.006 ± 0.022	1.235ArgMet: 1.235 ± 0.009	2.308ArgAsn: 2.308 ± 0.012	2.485ArgPro: 2.485 ± 0.017	2.476ArgGln: 2.476 ± 0.015	3.607ArgArg: 3.607 ± 0.025	3.884ArgSer: 3.884 ± 0.022	2.694ArgThr: 2.694 ± 0.014	2.751ArgVal: 2.751 ± 0.013	0.669ArgTrp: 0.669 ± 0.007	1.566ArgTyr: 1.566 ± 0.01	0.001ArgXaa: 0.001 ± 0.0
Ser	4.781SerAla: 4.781 ± 0.02	1.87SerCys: 1.87 ± 0.016	3.786SerAsp: 3.786 ± 0.019	5.038SerGlu: 5.038 ± 0.023	3.495SerPhe: 3.495 ± 0.02	5.019SerGly: 5.019 ± 0.025	2.125SerHis: 2.125 ± 0.015	3.87SerIle: 3.87 ± 0.018	4.35SerLys: 4.35 ± 0.023	8.298SerLeu: 8.298 ± 0.027	1.636SerMet: 1.636 ± 0.011	3.155SerAsn: 3.155 ± 0.017	5.264SerPro: 5.264 ± 0.03	3.639SerGln: 3.639 ± 0.022	4.085SerArg: 4.085 ± 0.021	8.961SerSer: 8.961 ± 0.05	4.365SerThr: 4.365 ± 0.02	4.804SerVal: 4.804 ± 0.017	1.044SerTrp: 1.044 ± 0.009	2.222SerTyr: 2.222 ± 0.016	0.002SerXaa: 0.002 ± 0.0
Thr	3.486ThrAla: 3.486 ± 0.017	1.3ThrCys: 1.3 ± 0.016	2.474ThrAsp: 2.474 ± 0.015	3.627ThrGlu: 3.627 ± 0.02	2.27ThrPhe: 2.27 ± 0.013	3.492ThrGly: 3.492 ± 0.022	1.257ThrHis: 1.257 ± 0.011	2.777ThrIle: 2.777 ± 0.014	2.828ThrLys: 2.828 ± 0.016	5.204ThrLeu: 5.204 ± 0.019	1.151ThrMet: 1.151 ± 0.009	1.966ThrAsn: 1.966 ± 0.011	3.089ThrPro: 3.089 ± 0.021	2.091ThrGln: 2.091 ± 0.013	2.216ThrArg: 2.216 ± 0.012	4.57ThrSer: 4.57 ± 0.021	2.916ThrThr: 2.916 ± 0.017	3.709ThrVal: 3.709 ± 0.017	0.694ThrTrp: 0.694 ± 0.007	1.551ThrTyr: 1.551 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	3.985ValAla: 3.985 ± 0.02	1.452ValCys: 1.452 ± 0.013	2.903ValAsp: 2.903 ± 0.017	3.868ValGlu: 3.868 ± 0.019	2.545ValPhe: 2.545 ± 0.015	3.235ValGly: 3.235 ± 0.016	1.535ValHis: 1.535 ± 0.01	3.216ValIle: 3.216 ± 0.017	3.61ValLys: 3.61 ± 0.015	6.057ValLeu: 6.057 ± 0.022	1.352ValMet: 1.352 ± 0.009	2.479ValAsn: 2.479 ± 0.014	3.182ValPro: 3.182 ± 0.016	2.691ValGln: 2.691 ± 0.015	2.833ValArg: 2.833 ± 0.014	4.717ValSer: 4.717 ± 0.016	3.523ValThr: 3.523 ± 0.018	3.805ValVal: 3.805 ± 0.019	0.701ValTrp: 0.701 ± 0.007	1.701ValTyr: 1.701 ± 0.011	0.0ValXaa: 0.0 ± 0.0
Trp	0.705TrpAla: 0.705 ± 0.006	0.247TrpCys: 0.247 ± 0.004	0.659TrpAsp: 0.659 ± 0.008	0.808TrpGlu: 0.808 ± 0.007	0.478TrpPhe: 0.478 ± 0.006	0.682TrpGly: 0.682 ± 0.008	0.319TrpHis: 0.319 ± 0.005	0.674TrpIle: 0.674 ± 0.007	0.889TrpLys: 0.889 ± 0.007	1.288TrpLeu: 1.288 ± 0.011	0.335TrpMet: 0.335 ± 0.005	0.609TrpAsn: 0.609 ± 0.006	0.484TrpPro: 0.484 ± 0.006	0.564TrpGln: 0.564 ± 0.005	0.661TrpArg: 0.661 ± 0.006	0.896TrpSer: 0.896 ± 0.009	0.644TrpThr: 0.644 ± 0.007	0.678TrpVal: 0.678 ± 0.007	0.208TrpTrp: 0.208 ± 0.004	0.357TrpTyr: 0.357 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.495TyrAla: 1.495 ± 0.01	0.764TyrCys: 0.764 ± 0.007	1.431TyrAsp: 1.431 ± 0.01	1.789TyrGlu: 1.789 ± 0.012	1.438TyrPhe: 1.438 ± 0.011	1.752TyrGly: 1.752 ± 0.013	0.837TyrHis: 0.837 ± 0.008	1.744TyrIle: 1.744 ± 0.013	1.849TyrLys: 1.849 ± 0.025	2.987TyrLeu: 2.987 ± 0.017	0.665TyrMet: 0.665 ± 0.006	1.332TyrAsn: 1.332 ± 0.01	1.319TyrPro: 1.319 ± 0.011	1.365TyrGln: 1.365 ± 0.009	1.637TyrArg: 1.637 ± 0.014	2.349TyrSer: 2.349 ± 0.014	1.609TyrThr: 1.609 ± 0.012	1.622TyrVal: 1.622 ± 0.012	0.394TyrTrp: 0.394 ± 0.006	1.067TyrTyr: 1.067 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.061XaaXaa: 0.061 ± 0.006

Statistics based on 27547 proteins (16957327 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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