Sphingomonas laterariae

Taxonomy: cellular organisms; Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales; Sphingomonadaceae; Sphingomonas

Average proteome isoelectric point is 6.51

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 4276 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A239J1C2|A0A239J1C2_9SPHN Integrase OS=Sphingomonas laterariae OX=861865 GN=SAMN06295912_12918 PE=4 SV=1
MM1 pKa = 7.36TSDD4 pKa = 3.11ILMNAILSLDD14 pKa = 3.68AYY16 pKa = 10.7NRR18 pKa = 11.84GYY20 pKa = 10.87DD21 pKa = 3.2AGVQITEE28 pKa = 4.58PDD30 pKa = 4.52DD31 pKa = 3.16ITPYY35 pKa = 10.71KK36 pKa = 10.33VGNATFLKK44 pKa = 9.49QSSVAEE50 pKa = 4.07SSEE53 pKa = 3.88GVTAGFYY60 pKa = 10.67AIAYY64 pKa = 8.08SYY66 pKa = 11.23NGEE69 pKa = 4.23TVISYY74 pKa = 10.46RR75 pKa = 11.84GTDD78 pKa = 3.81DD79 pKa = 3.57YY80 pKa = 12.03DD81 pKa = 5.27GITSIPSSLDD91 pKa = 3.21AANGWPMGGGSITTAQGRR109 pKa = 11.84MALEE113 pKa = 4.82FYY115 pKa = 10.94KK116 pKa = 10.83DD117 pKa = 3.83VADD120 pKa = 4.48LPYY123 pKa = 10.94GSDD126 pKa = 3.38LRR128 pKa = 11.84NVAITLTGHH137 pKa = 5.85SLGGGLAGYY146 pKa = 8.81VASLYY151 pKa = 9.94GQNADD156 pKa = 4.3IFDD159 pKa = 3.78SMAFKK164 pKa = 10.68LAATATINVAYY175 pKa = 10.02HH176 pKa = 6.1PEE178 pKa = 4.48YY179 pKa = 10.15YY180 pKa = 9.84TDD182 pKa = 3.52PEE184 pKa = 4.74YY185 pKa = 11.09YY186 pKa = 9.7PEE188 pKa = 5.76PIFSDD193 pKa = 3.43AQEE196 pKa = 4.06LVYY199 pKa = 10.84NGYY202 pKa = 7.98STPWEE207 pKa = 4.19NSHH210 pKa = 6.85PEE212 pKa = 3.97YY213 pKa = 11.22VNGYY217 pKa = 8.02EE218 pKa = 5.33LSGQVISEE226 pKa = 4.38EE227 pKa = 3.69NWYY230 pKa = 6.7PTPGVDD236 pKa = 3.19SVGYY240 pKa = 8.25NTYY243 pKa = 11.17DD244 pKa = 5.27DD245 pKa = 5.41GDD247 pKa = 4.03LDD249 pKa = 5.25SNDD252 pKa = 3.46KK253 pKa = 11.03HH254 pKa = 8.04SMSSFVIRR262 pKa = 11.84YY263 pKa = 6.44YY264 pKa = 11.44AEE266 pKa = 3.71VGGANDD272 pKa = 4.01SALSTDD278 pKa = 3.35WQNAAPYY285 pKa = 8.7FWAVLYY291 pKa = 10.49DD292 pKa = 3.84DD293 pKa = 5.3QLAQAIGADD302 pKa = 3.84AKK304 pKa = 11.17DD305 pKa = 3.56GTLKK309 pKa = 11.11DD310 pKa = 3.34EE311 pKa = 4.51GKK313 pKa = 9.86YY314 pKa = 10.81AEE316 pKa = 4.24IVRR319 pKa = 11.84TAIAYY324 pKa = 9.66SSLEE328 pKa = 4.08KK329 pKa = 11.0NVDD332 pKa = 3.14GTGLIFGDD340 pKa = 3.35TGIRR344 pKa = 11.84ALYY347 pKa = 10.61DD348 pKa = 3.52DD349 pKa = 5.58ANDD352 pKa = 3.55LGARR356 pKa = 11.84IADD359 pKa = 4.16PLSGDD364 pKa = 3.86LFDD367 pKa = 4.42TYY369 pKa = 11.01GTVISRR375 pKa = 11.84AFVEE379 pKa = 4.95FAGSLALHH387 pKa = 6.84EE388 pKa = 4.23IEE390 pKa = 4.08KK391 pKa = 10.17TEE393 pKa = 3.83FAGAINGVLSHH404 pKa = 7.57DD405 pKa = 4.14ATNHH409 pKa = 5.21TLTVNYY415 pKa = 10.6ADD417 pKa = 4.87ALWIAAGKK425 pKa = 8.94GANDD429 pKa = 3.76IIVSRR434 pKa = 11.84EE435 pKa = 3.96NIVEE439 pKa = 3.97QAFGVDD445 pKa = 3.49EE446 pKa = 4.48TQLRR450 pKa = 11.84TAMWDD455 pKa = 3.03LWQNDD460 pKa = 3.28GNAVFDD466 pKa = 3.87KK467 pKa = 11.33VIFSTVAHH475 pKa = 6.64SLTVIPSSADD485 pKa = 3.14TEE487 pKa = 4.46YY488 pKa = 11.73GLVIANGNNQDD499 pKa = 3.45YY500 pKa = 10.32QSRR503 pKa = 11.84VEE505 pKa = 4.79IDD507 pKa = 3.84DD508 pKa = 4.13DD509 pKa = 4.78ANYY512 pKa = 10.82LVIGSDD518 pKa = 3.07AKK520 pKa = 11.11DD521 pKa = 3.42IIVTGAGDD529 pKa = 4.0TIVSGGAGDD538 pKa = 4.97DD539 pKa = 4.83DD540 pKa = 3.7ITGGVGQDD548 pKa = 3.25IIFGGVGQDD557 pKa = 3.33HH558 pKa = 6.44VEE560 pKa = 4.29SGAGADD566 pKa = 3.53VVYY569 pKa = 10.79GGDD572 pKa = 4.5DD573 pKa = 3.6NDD575 pKa = 3.99TFIAQIGPMGLGGDD589 pKa = 3.95TYY591 pKa = 11.46YY592 pKa = 11.3GGDD595 pKa = 3.24ATSRR599 pKa = 11.84GSVDD603 pKa = 2.57GWDD606 pKa = 3.42VVDD609 pKa = 4.47YY610 pKa = 10.75RR611 pKa = 11.84QLDD614 pKa = 3.76TEE616 pKa = 4.71LYY618 pKa = 9.98GLAFEE623 pKa = 5.01QVDD626 pKa = 3.3AGHH629 pKa = 6.89RR630 pKa = 11.84RR631 pKa = 11.84LFMYY635 pKa = 9.59VKK637 pKa = 10.56NPGEE641 pKa = 4.03AQPLVFEE648 pKa = 5.23NYY650 pKa = 10.16DD651 pKa = 3.43DD652 pKa = 4.86LYY654 pKa = 10.93SIEE657 pKa = 5.24SILHH661 pKa = 5.69NDD663 pKa = 3.32YY664 pKa = 11.35LFDD667 pKa = 3.65VQFGDD672 pKa = 3.82EE673 pKa = 4.08VANNIRR679 pKa = 11.84AGDD682 pKa = 3.7SGGSGGGIVYY692 pKa = 10.15GRR694 pKa = 11.84GGNDD698 pKa = 3.27VLRR701 pKa = 11.84GASYY705 pKa = 8.36DD706 pKa = 3.57TNYY709 pKa = 10.97LFGEE713 pKa = 4.71DD714 pKa = 4.74GNDD717 pKa = 3.21TLYY720 pKa = 11.28SGDD723 pKa = 3.75AVNGSKK729 pKa = 10.7NFLWGGSGDD738 pKa = 3.76DD739 pKa = 3.7TLVGDD744 pKa = 3.89RR745 pKa = 11.84GEE747 pKa = 3.87NHH749 pKa = 7.45LYY751 pKa = 11.09GEE753 pKa = 4.55TGNDD757 pKa = 3.12TLTIANGGSGVYY769 pKa = 10.31DD770 pKa = 3.9GGADD774 pKa = 3.58FDD776 pKa = 4.64LVSGNLTNKK785 pKa = 9.39MYY787 pKa = 11.05LFADD791 pKa = 3.92TLSEE795 pKa = 4.15GGTYY799 pKa = 10.2TFVDD803 pKa = 3.23ADD805 pKa = 4.1GNNSLTVKK813 pKa = 10.47NMEE816 pKa = 4.2RR817 pKa = 11.84VGLTLSQTHH826 pKa = 6.22IAVTDD831 pKa = 3.62TQSFSNYY838 pKa = 9.2YY839 pKa = 8.59YY840 pKa = 11.37ANDD843 pKa = 3.95GEE845 pKa = 4.58FNYY848 pKa = 10.71LSLYY852 pKa = 10.02KK853 pKa = 10.61AIFDD857 pKa = 4.05FSGSEE862 pKa = 3.78TALTHH867 pKa = 6.08DD868 pKa = 3.68TAGYY872 pKa = 9.46GYY874 pKa = 11.09VNGVYY879 pKa = 9.98TLMDD883 pKa = 3.58YY884 pKa = 10.39EE885 pKa = 4.72VNGGSYY891 pKa = 7.43THH893 pKa = 6.27YY894 pKa = 8.83VQNVAGVVGSNMGDD908 pKa = 3.39TYY910 pKa = 11.67NLNSQQTTLYY920 pKa = 9.54MGTGDD925 pKa = 3.7DD926 pKa = 3.92TVNMGSRR933 pKa = 11.84TANDD937 pKa = 3.45VIYY940 pKa = 10.99SGGNDD945 pKa = 3.16VFYY948 pKa = 11.25SEE950 pKa = 5.49YY951 pKa = 9.27YY952 pKa = 10.63LPGITVDD959 pKa = 4.31AKK961 pKa = 10.88FLNTDD966 pKa = 2.98ATVTINSSLYY976 pKa = 10.92DD977 pKa = 3.58NGLSKK982 pKa = 11.08LDD984 pKa = 3.34ILFTFDD990 pKa = 4.14ADD992 pKa = 3.71NSIHH996 pKa = 6.7IIWEE1000 pKa = 4.31GSSYY1004 pKa = 10.85SASSSLKK1011 pKa = 9.75FYY1013 pKa = 10.72NATRR1017 pKa = 11.84IDD1019 pKa = 3.79FNGPQLMNPGSPDD1032 pKa = 3.38AYY1034 pKa = 10.57VKK1036 pKa = 10.46AAEE1039 pKa = 4.04YY1040 pKa = 10.58SLVGSTPVASTLEE1053 pKa = 4.18GTLGHH1058 pKa = 6.34DD1059 pKa = 4.1TIVSRR1064 pKa = 11.84SGYY1067 pKa = 8.56GQALIGLWGDD1077 pKa = 3.66DD1078 pKa = 3.55KK1079 pKa = 11.75LYY1081 pKa = 10.84GYY1083 pKa = 10.63DD1084 pKa = 4.96GADD1087 pKa = 3.45TLQGGAGDD1095 pKa = 3.75DD1096 pKa = 3.63TLYY1099 pKa = 11.22GGTGDD1104 pKa = 5.14DD1105 pKa = 4.15VLTGGADD1112 pKa = 3.15NDD1114 pKa = 3.65EE1115 pKa = 5.5FIFEE1119 pKa = 4.61SGFGHH1124 pKa = 6.95DD1125 pKa = 4.27TITDD1129 pKa = 4.13FVRR1132 pKa = 11.84GSDD1135 pKa = 3.78KK1136 pKa = 10.37ITFDD1140 pKa = 3.84SLSGIDD1146 pKa = 5.13DD1147 pKa = 3.73MSDD1150 pKa = 2.92LTFSAEE1156 pKa = 4.41TPTSTRR1162 pKa = 11.84IAVDD1166 pKa = 3.39SNNWVIVANQEE1177 pKa = 3.62FDD1179 pKa = 3.06SWLVSDD1185 pKa = 5.56FGFSTLLPVNGTSANDD1201 pKa = 3.45ILDD1204 pKa = 3.99GTSAAEE1210 pKa = 4.06EE1211 pKa = 3.99FHH1213 pKa = 7.16AGAGNDD1219 pKa = 3.57YY1220 pKa = 10.79VYY1222 pKa = 10.99AGAGNDD1228 pKa = 3.42VLYY1231 pKa = 11.23GEE1233 pKa = 5.57DD1234 pKa = 4.41GDD1236 pKa = 6.21DD1237 pKa = 3.35ILAGQFGNDD1246 pKa = 3.14TLYY1249 pKa = 11.2GGNGGDD1255 pKa = 3.64YY1256 pKa = 10.93LWGNEE1261 pKa = 4.53GNDD1264 pKa = 3.63TLYY1267 pKa = 11.33GGAGVDD1273 pKa = 3.4ALRR1276 pKa = 11.84GLEE1279 pKa = 4.42GDD1281 pKa = 5.04DD1282 pKa = 3.87ILHH1285 pKa = 6.83GGDD1288 pKa = 3.85GNDD1291 pKa = 3.45NLRR1294 pKa = 11.84GDD1296 pKa = 5.29DD1297 pKa = 3.76VDD1299 pKa = 4.74SDD1301 pKa = 4.08PSFAGAGNDD1310 pKa = 3.65ILYY1313 pKa = 10.78GDD1315 pKa = 5.01AGNDD1319 pKa = 3.49SLAGGAGNDD1328 pKa = 3.33ILRR1331 pKa = 11.84GGTGQDD1337 pKa = 3.8SLWGNAGSDD1346 pKa = 3.34TFLFMAEE1353 pKa = 4.4DD1354 pKa = 3.98LDD1356 pKa = 4.08GNRR1359 pKa = 11.84DD1360 pKa = 3.71YY1361 pKa = 10.93IYY1363 pKa = 10.79DD1364 pKa = 3.66FTVGSGGDD1372 pKa = 3.65MIDD1375 pKa = 3.3ISDD1378 pKa = 3.89VLSGYY1383 pKa = 10.95DD1384 pKa = 3.4SANDD1388 pKa = 3.45NLADD1392 pKa = 4.04FVSILTGGSYY1402 pKa = 9.82TRR1404 pKa = 11.84ISVDD1408 pKa = 2.79IDD1410 pKa = 3.59GTGTNYY1416 pKa = 10.39GSQSIIQIQGVTGLTLNDD1434 pKa = 3.35LTTNGNLIVEE1444 pKa = 4.82AAA1446 pKa = 3.69

Molecular weight: 153.52 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A239EUW1|A0A239EUW1_9SPHN 3-hydroxyisobutyrate dehydrogenase OS=Sphingomonas laterariae OX=861865 GN=SAMN06295912_107112 PE=4 SV=1
MM1 pKa = 7.45KK2 pKa = 9.61RR3 pKa = 11.84TFQPSNLVRR12 pKa = 11.84KK13 pKa = 8.96RR14 pKa = 11.84RR15 pKa = 11.84HH16 pKa = 4.61GFRR19 pKa = 11.84SRR21 pKa = 11.84SATPGGRR28 pKa = 11.84KK29 pKa = 9.04VLAARR34 pKa = 11.84RR35 pKa = 11.84ARR37 pKa = 11.84GRR39 pKa = 11.84KK40 pKa = 9.07SLSAA44 pKa = 3.93

Molecular weight: 5.01 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4276

0

4276

1329728

27

4406

311.0

33.53

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

14.033 ± 0.065

0.751 ± 0.011

6.17 ± 0.03

5.334 ± 0.04

3.496 ± 0.025

9.019 ± 0.062

1.998 ± 0.019

5.168 ± 0.028

2.878 ± 0.028

9.725 ± 0.043

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.402 ± 0.021

2.454 ± 0.024

5.376 ± 0.033

3.005 ± 0.021

7.568 ± 0.044

4.881 ± 0.027

5.141 ± 0.038

6.994 ± 0.033

1.44 ± 0.017

2.166 ± 0.022
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski