Amino acid dipepetide frequency for Yongjia Tick Virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.54AlaAla: 2.54 ± 1.141
1.693AlaCys: 1.693 ± 0.992
2.258AlaAsp: 2.258 ± 1.044
3.387AlaGlu: 3.387 ± 0.923
1.129AlaPhe: 1.129 ± 0.276
2.822AlaGly: 2.822 ± 0.938
1.411AlaHis: 1.411 ± 0.454
3.105AlaIle: 3.105 ± 0.922
1.976AlaLys: 1.976 ± 1.037
4.798AlaLeu: 4.798 ± 1.406
0.564AlaMet: 0.564 ± 0.665
1.976AlaAsn: 1.976 ± 1.037
1.129AlaPro: 1.129 ± 0.443
2.822AlaGln: 2.822 ± 1.131
3.105AlaArg: 3.105 ± 0.955
2.54AlaSer: 2.54 ± 0.481
5.08AlaThr: 5.08 ± 1.961
1.693AlaVal: 1.693 ± 0.729
0.282AlaTrp: 0.282 ± 0.417
1.693AlaTyr: 1.693 ± 0.751
0.0AlaXaa: 0.0 ± 0.0
Cys
1.129CysAla: 1.129 ± 0.387
0.0CysCys: 0.0 ± 0.0
0.282CysAsp: 0.282 ± 0.165
1.129CysGlu: 1.129 ± 0.443
0.564CysPhe: 0.564 ± 0.331
0.847CysGly: 0.847 ± 0.683
1.976CysHis: 1.976 ± 1.818
0.847CysIle: 0.847 ± 0.496
1.129CysLys: 1.129 ± 0.433
3.387CysLeu: 3.387 ± 0.874
0.282CysMet: 0.282 ± 0.417
1.129CysAsn: 1.129 ± 0.387
1.693CysPro: 1.693 ± 0.729
0.564CysGln: 0.564 ± 0.331
0.564CysArg: 0.564 ± 0.351
1.411CysSer: 1.411 ± 0.508
1.411CysThr: 1.411 ± 0.56
0.847CysVal: 0.847 ± 0.683
0.282CysTrp: 0.282 ± 0.165
0.564CysTyr: 0.564 ± 0.31
0.0CysXaa: 0.0 ± 0.0
Asp
0.847AspAla: 0.847 ± 0.359
0.282AspCys: 0.282 ± 0.388
3.105AspAsp: 3.105 ± 1.156
4.516AspGlu: 4.516 ± 1.09
1.411AspPhe: 1.411 ± 0.826
2.54AspGly: 2.54 ± 0.74
1.129AspHis: 1.129 ± 0.661
1.693AspIle: 1.693 ± 0.393
1.976AspLys: 1.976 ± 0.951
7.903AspLeu: 7.903 ± 0.8
2.54AspMet: 2.54 ± 0.659
1.693AspAsn: 1.693 ± 0.698
3.951AspPro: 3.951 ± 0.519
2.822AspGln: 2.822 ± 1.324
1.693AspArg: 1.693 ± 0.349
3.669AspSer: 3.669 ± 1.456
5.363AspThr: 5.363 ± 0.897
3.105AspVal: 3.105 ± 0.683
0.564AspTrp: 0.564 ± 0.535
2.822AspTyr: 2.822 ± 1.098
0.0AspXaa: 0.0 ± 0.0
Glu
2.822GluAla: 2.822 ± 0.562
0.564GluCys: 0.564 ± 0.613
4.516GluAsp: 4.516 ± 1.819
4.234GluGlu: 4.234 ± 1.372
2.54GluPhe: 2.54 ± 0.568
7.056GluGly: 7.056 ± 1.073
1.411GluHis: 1.411 ± 0.697
4.234GluIle: 4.234 ± 0.156
3.669GluLys: 3.669 ± 0.246
6.209GluLeu: 6.209 ± 1.521
1.411GluMet: 1.411 ± 0.571
1.411GluAsn: 1.411 ± 1.184
4.234GluPro: 4.234 ± 1.258
0.847GluGln: 0.847 ± 0.767
3.105GluArg: 3.105 ± 0.322
5.08GluSer: 5.08 ± 1.284
2.822GluThr: 2.822 ± 1.006
4.234GluVal: 4.234 ± 1.037
0.282GluTrp: 0.282 ± 0.165
2.258GluTyr: 2.258 ± 0.477
0.0GluXaa: 0.0 ± 0.0
Phe
1.129PheAla: 1.129 ± 0.433
1.411PheCys: 1.411 ± 1.147
1.976PheAsp: 1.976 ± 0.544
1.411PheGlu: 1.411 ± 0.697
1.693PhePhe: 1.693 ± 0.552
2.258PheGly: 2.258 ± 0.577
1.129PheHis: 1.129 ± 0.697
0.564PheIle: 0.564 ± 0.331
3.387PheLys: 3.387 ± 0.527
3.669PheLeu: 3.669 ± 1.541
0.564PheMet: 0.564 ± 0.352
0.564PheAsn: 0.564 ± 0.535
2.54PhePro: 2.54 ± 0.619
2.258PheGln: 2.258 ± 0.249
3.105PheArg: 3.105 ± 1.46
3.387PheSer: 3.387 ± 0.977
0.847PheThr: 0.847 ± 0.496
2.54PheVal: 2.54 ± 1.107
0.282PheTrp: 0.282 ± 0.165
1.411PheTyr: 1.411 ± 0.571
0.0PheXaa: 0.0 ± 0.0
Gly
2.822GlyAla: 2.822 ± 1.098
0.847GlyCys: 0.847 ± 0.496
3.105GlyAsp: 3.105 ± 1.154
3.387GlyGlu: 3.387 ± 1.064
1.693GlyPhe: 1.693 ± 0.728
4.798GlyGly: 4.798 ± 1.218
0.564GlyHis: 0.564 ± 0.351
3.669GlyIle: 3.669 ± 0.948
4.798GlyLys: 4.798 ± 0.393
9.032GlyLeu: 9.032 ± 0.977
1.129GlyMet: 1.129 ± 0.534
1.976GlyAsn: 1.976 ± 0.83
4.234GlyPro: 4.234 ± 0.693
3.387GlyGln: 3.387 ± 1.0
2.822GlyArg: 2.822 ± 0.983
5.927GlySer: 5.927 ± 1.074
4.798GlyThr: 4.798 ± 0.926
4.798GlyVal: 4.798 ± 1.001
1.976GlyTrp: 1.976 ± 0.586
1.411GlyTyr: 1.411 ± 0.508
0.0GlyXaa: 0.0 ± 0.0
His
1.129HisAla: 1.129 ± 0.276
0.847HisCys: 0.847 ± 0.496
1.129HisAsp: 1.129 ± 1.049
1.693HisGlu: 1.693 ± 0.481
0.847HisPhe: 0.847 ± 0.359
1.129HisGly: 1.129 ± 0.417
2.258HisHis: 2.258 ± 0.897
1.411HisIle: 1.411 ± 0.549
2.54HisLys: 2.54 ± 1.305
3.951HisLeu: 3.951 ± 0.966
0.282HisMet: 0.282 ± 0.165
1.129HisAsn: 1.129 ± 0.619
2.54HisPro: 2.54 ± 1.115
1.411HisGln: 1.411 ± 0.826
1.693HisArg: 1.693 ± 0.652
2.258HisSer: 2.258 ± 0.58
0.847HisThr: 0.847 ± 0.496
2.258HisVal: 2.258 ± 0.693
0.847HisTrp: 0.847 ± 0.496
1.129HisTyr: 1.129 ± 0.411
0.0HisXaa: 0.0 ± 0.0
Ile
1.693IleAla: 1.693 ± 0.464
1.976IleCys: 1.976 ± 0.586
2.822IleAsp: 2.822 ± 0.979
2.54IleGlu: 2.54 ± 1.19
1.693IlePhe: 1.693 ± 0.685
4.516IleGly: 4.516 ± 1.844
3.387IleHis: 3.387 ± 1.299
4.234IleIle: 4.234 ± 1.014
3.669IleLys: 3.669 ± 0.948
7.621IleLeu: 7.621 ± 1.266
0.564IleMet: 0.564 ± 0.331
2.822IleAsn: 2.822 ± 0.836
4.516IlePro: 4.516 ± 2.271
1.976IleGln: 1.976 ± 0.479
2.258IleArg: 2.258 ± 0.249
2.54IleSer: 2.54 ± 0.36
4.516IleThr: 4.516 ± 1.886
2.54IleVal: 2.54 ± 0.518
0.564IleTrp: 0.564 ± 0.352
1.693IleTyr: 1.693 ± 1.415
0.0IleXaa: 0.0 ± 0.0
Lys
3.669LysAla: 3.669 ± 1.091
0.847LysCys: 0.847 ± 0.496
3.669LysAsp: 3.669 ± 0.52
5.363LysGlu: 5.363 ± 0.787
1.411LysPhe: 1.411 ± 0.636
3.951LysGly: 3.951 ± 0.489
1.411LysHis: 1.411 ± 0.637
3.951LysIle: 3.951 ± 0.614
4.234LysLys: 4.234 ± 1.003
5.08LysLeu: 5.08 ± 0.669
0.847LysMet: 0.847 ± 0.364
2.258LysAsn: 2.258 ± 0.65
1.693LysPro: 1.693 ± 0.552
2.258LysGln: 2.258 ± 0.997
5.363LysArg: 5.363 ± 0.866
3.105LysSer: 3.105 ± 1.071
3.669LysThr: 3.669 ± 0.799
3.105LysVal: 3.105 ± 0.622
1.411LysTrp: 1.411 ± 0.23
0.847LysTyr: 0.847 ± 0.342
0.0LysXaa: 0.0 ± 0.0
Leu
7.056LeuAla: 7.056 ± 1.514
3.105LeuCys: 3.105 ± 0.889
5.645LeuAsp: 5.645 ± 0.716
5.645LeuGlu: 5.645 ± 1.409
3.951LeuPhe: 3.951 ± 1.6
8.185LeuGly: 8.185 ± 1.17
2.258LeuHis: 2.258 ± 0.653
6.774LeuIle: 6.774 ± 1.546
7.338LeuLys: 7.338 ± 0.524
9.879LeuLeu: 9.879 ± 2.328
2.822LeuMet: 2.822 ± 0.869
6.209LeuAsn: 6.209 ± 1.379
5.363LeuPro: 5.363 ± 1.465
3.951LeuGln: 3.951 ± 0.614
7.903LeuArg: 7.903 ± 2.157
9.314LeuSer: 9.314 ± 0.737
5.645LeuThr: 5.645 ± 0.667
5.645LeuVal: 5.645 ± 0.544
1.411LeuTrp: 1.411 ± 0.23
1.693LeuTyr: 1.693 ± 0.698
0.0LeuXaa: 0.0 ± 0.0
Met
1.411MetAla: 1.411 ± 0.23
0.0MetCys: 0.0 ± 0.0
0.282MetAsp: 0.282 ± 0.429
2.54MetGlu: 2.54 ± 1.317
1.693MetPhe: 1.693 ± 0.685
1.693MetGly: 1.693 ± 0.469
0.0MetHis: 0.0 ± 0.0
1.411MetIle: 1.411 ± 0.436
1.693MetLys: 1.693 ± 1.228
2.822MetLeu: 2.822 ± 0.379
0.282MetMet: 0.282 ± 0.417
0.847MetAsn: 0.847 ± 0.393
0.564MetPro: 0.564 ± 0.331
0.847MetGln: 0.847 ± 0.393
1.129MetArg: 1.129 ± 0.387
1.129MetSer: 1.129 ± 0.433
1.693MetThr: 1.693 ± 0.698
0.847MetVal: 0.847 ± 1.004
0.0MetTrp: 0.0 ± 0.0
0.282MetTyr: 0.282 ± 0.165
0.0MetXaa: 0.0 ± 0.0
Asn
1.411AsnAla: 1.411 ± 1.147
0.282AsnCys: 0.282 ± 0.388
2.822AsnAsp: 2.822 ± 0.316
1.129AsnGlu: 1.129 ± 0.411
1.976AsnPhe: 1.976 ± 0.538
2.822AsnGly: 2.822 ± 1.215
2.258AsnHis: 2.258 ± 0.718
2.54AsnIle: 2.54 ± 0.888
0.564AsnLys: 0.564 ± 0.352
4.798AsnLeu: 4.798 ± 0.992
0.282AsnMet: 0.282 ± 0.165
1.693AsnAsn: 1.693 ± 0.552
1.693AsnPro: 1.693 ± 1.213
0.564AsnGln: 0.564 ± 0.331
1.693AsnArg: 1.693 ± 0.437
4.516AsnSer: 4.516 ± 0.802
1.693AsnThr: 1.693 ± 0.804
2.258AsnVal: 2.258 ± 0.614
1.129AsnTrp: 1.129 ± 0.387
1.693AsnTyr: 1.693 ± 0.698
0.282AsnXaa: 0.282 ± 0.165
Pro
1.976ProAla: 1.976 ± 0.587
0.282ProCys: 0.282 ± 0.412
2.258ProAsp: 2.258 ± 0.955
3.669ProGlu: 3.669 ± 0.841
1.411ProPhe: 1.411 ± 0.23
2.54ProGly: 2.54 ± 1.144
1.976ProHis: 1.976 ± 1.315
2.54ProIle: 2.54 ± 0.743
2.822ProLys: 2.822 ± 0.766
6.209ProLeu: 6.209 ± 1.262
0.847ProMet: 0.847 ± 0.502
1.976ProAsn: 1.976 ± 0.254
1.976ProPro: 1.976 ± 0.422
0.847ProGln: 0.847 ± 0.878
3.951ProArg: 3.951 ± 0.874
5.363ProSer: 5.363 ± 1.017
3.387ProThr: 3.387 ± 1.739
4.798ProVal: 4.798 ± 0.927
0.564ProTrp: 0.564 ± 0.352
2.54ProTyr: 2.54 ± 0.972
0.0ProXaa: 0.0 ± 0.0
Gln
1.411GlnAla: 1.411 ± 0.673
1.129GlnCys: 1.129 ± 1.067
1.976GlnAsp: 1.976 ± 1.968
1.976GlnGlu: 1.976 ± 1.068
1.693GlnPhe: 1.693 ± 0.29
1.411GlnGly: 1.411 ± 0.596
0.564GlnHis: 0.564 ± 0.331
3.951GlnIle: 3.951 ± 1.796
1.129GlnLys: 1.129 ± 0.632
2.822GlnLeu: 2.822 ± 0.466
0.847GlnMet: 0.847 ± 0.683
1.693GlnAsn: 1.693 ± 0.349
1.129GlnPro: 1.129 ± 0.443
1.693GlnGln: 1.693 ± 0.929
2.822GlnArg: 2.822 ± 0.508
1.976GlnSer: 1.976 ± 1.157
2.54GlnThr: 2.54 ± 0.787
3.951GlnVal: 3.951 ± 1.148
0.564GlnTrp: 0.564 ± 0.352
0.564GlnTyr: 0.564 ± 0.352
0.0GlnXaa: 0.0 ± 0.0
Arg
3.105ArgAla: 3.105 ± 0.715
1.693ArgCys: 1.693 ± 0.996
3.951ArgAsp: 3.951 ± 0.825
3.669ArgGlu: 3.669 ± 1.153
2.258ArgPhe: 2.258 ± 0.703
3.669ArgGly: 3.669 ± 1.043
2.54ArgHis: 2.54 ± 0.888
2.822ArgIle: 2.822 ± 0.535
2.822ArgLys: 2.822 ± 1.041
4.798ArgLeu: 4.798 ± 1.095
1.976ArgMet: 1.976 ± 0.561
1.693ArgAsn: 1.693 ± 0.649
3.105ArgPro: 3.105 ± 0.649
3.105ArgGln: 3.105 ± 0.622
2.54ArgArg: 2.54 ± 0.486
4.798ArgSer: 4.798 ± 1.489
3.105ArgThr: 3.105 ± 0.618
3.387ArgVal: 3.387 ± 0.439
1.129ArgTrp: 1.129 ± 0.387
2.54ArgTyr: 2.54 ± 0.493
0.0ArgXaa: 0.0 ± 0.0
Ser
2.822SerAla: 2.822 ± 0.886
1.129SerCys: 1.129 ± 0.276
5.08SerAsp: 5.08 ± 1.217
4.516SerGlu: 4.516 ± 0.97
3.387SerPhe: 3.387 ± 0.988
5.363SerGly: 5.363 ± 1.077
2.54SerHis: 2.54 ± 0.888
3.105SerIle: 3.105 ± 0.683
4.798SerLys: 4.798 ± 1.216
8.467SerLeu: 8.467 ± 3.357
1.976SerMet: 1.976 ± 1.171
1.129SerAsn: 1.129 ± 0.406
1.976SerPro: 1.976 ± 0.658
0.847SerGln: 0.847 ± 0.359
5.363SerArg: 5.363 ± 0.514
7.056SerSer: 7.056 ± 2.922
4.516SerThr: 4.516 ± 1.226
4.234SerVal: 4.234 ± 0.413
2.822SerTrp: 2.822 ± 1.653
2.54SerTyr: 2.54 ± 0.568
0.0SerXaa: 0.0 ± 0.0
Thr
3.669ThrAla: 3.669 ± 1.159
0.847ThrCys: 0.847 ± 0.364
3.105ThrAsp: 3.105 ± 1.156
4.798ThrGlu: 4.798 ± 2.228
1.411ThrPhe: 1.411 ± 0.508
4.516ThrGly: 4.516 ± 1.127
1.411ThrHis: 1.411 ± 0.719
2.258ThrIle: 2.258 ± 0.7
2.822ThrLys: 2.822 ± 1.273
7.338ThrLeu: 7.338 ± 1.575
1.129ThrMet: 1.129 ± 0.406
2.258ThrAsn: 2.258 ± 0.936
3.669ThrPro: 3.669 ± 0.931
1.976ThrGln: 1.976 ± 0.254
4.516ThrArg: 4.516 ± 1.165
3.105ThrSer: 3.105 ± 1.46
3.669ThrThr: 3.669 ± 1.456
5.645ThrVal: 5.645 ± 2.384
1.976ThrTrp: 1.976 ± 1.452
2.258ThrTyr: 2.258 ± 0.944
0.0ThrXaa: 0.0 ± 0.0
Val
2.54ValAla: 2.54 ± 0.844
2.258ValCys: 2.258 ± 0.95
3.105ValAsp: 3.105 ± 1.167
5.08ValGlu: 5.08 ± 1.684
2.822ValPhe: 2.822 ± 0.669
3.105ValGly: 3.105 ± 1.745
1.693ValHis: 1.693 ± 0.921
6.492ValIle: 6.492 ± 0.878
2.822ValLys: 2.822 ± 0.522
6.209ValLeu: 6.209 ± 0.912
1.129ValMet: 1.129 ± 0.469
2.54ValAsn: 2.54 ± 0.737
3.669ValPro: 3.669 ± 1.193
1.693ValGln: 1.693 ± 0.791
3.105ValArg: 3.105 ± 0.781
4.234ValSer: 4.234 ± 1.182
2.822ValThr: 2.822 ± 0.898
4.234ValVal: 4.234 ± 1.518
1.411ValTrp: 1.411 ± 0.475
2.54ValTyr: 2.54 ± 0.69
0.0ValXaa: 0.0 ± 0.0
Trp
1.976TrpAla: 1.976 ± 0.413
0.0TrpCys: 0.0 ± 0.0
0.847TrpAsp: 0.847 ± 0.309
1.129TrpGlu: 1.129 ± 0.661
1.411TrpPhe: 1.411 ± 0.23
1.693TrpGly: 1.693 ± 0.649
0.847TrpHis: 0.847 ± 0.496
0.564TrpIle: 0.564 ± 0.535
1.129TrpLys: 1.129 ± 0.387
0.847TrpLeu: 0.847 ± 0.496
0.847TrpMet: 0.847 ± 0.393
0.847TrpAsn: 0.847 ± 0.364
0.847TrpPro: 0.847 ± 0.496
0.282TrpGln: 0.282 ± 0.412
0.564TrpArg: 0.564 ± 0.31
0.564TrpSer: 0.564 ± 0.331
1.693TrpThr: 1.693 ± 0.936
1.411TrpVal: 1.411 ± 0.845
0.564TrpTrp: 0.564 ± 0.331
0.564TrpTyr: 0.564 ± 0.535
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.847TyrAla: 0.847 ± 0.359
0.847TyrCys: 0.847 ± 0.342
1.693TyrAsp: 1.693 ± 0.729
1.129TyrGlu: 1.129 ± 0.433
1.129TyrPhe: 1.129 ± 0.417
2.258TyrGly: 2.258 ± 0.742
0.564TyrHis: 0.564 ± 0.31
1.693TyrIle: 1.693 ± 0.552
2.822TyrLys: 2.822 ± 0.666
3.951TyrLeu: 3.951 ± 0.646
0.564TyrMet: 0.564 ± 0.31
2.258TyrAsn: 2.258 ± 0.812
1.411TyrPro: 1.411 ± 0.454
1.693TyrGln: 1.693 ± 0.649
1.693TyrArg: 1.693 ± 0.552
1.693TyrSer: 1.693 ± 0.552
2.258TyrThr: 2.258 ± 1.025
1.976TyrVal: 1.976 ± 0.672
0.564TyrTrp: 0.564 ± 0.31
1.411TyrTyr: 1.411 ± 0.517
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.282XaaIle: 0.282 ± 0.165
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3544 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski