Plasmodium falciparum (isolate Dd2)

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum

Average proteome isoelectric point is 7.12

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5132 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0L7LYD7|A0A0L7LYD7_PLAF4 Uncharacterized protein OS=Plasmodium falciparum (isolate Dd2) OX=57267 GN=PFDG_01042 PE=4 SV=1
MM1 pKa = 7.55DD2 pKa = 6.06TILEE6 pKa = 4.49DD7 pKa = 3.43LDD9 pKa = 4.49KK10 pKa = 11.55YY11 pKa = 10.97NEE13 pKa = 4.23PYY15 pKa = 10.95YY16 pKa = 10.59DD17 pKa = 3.76VQDD20 pKa = 4.67DD21 pKa = 3.99IYY23 pKa = 11.33YY24 pKa = 10.36DD25 pKa = 3.66VHH27 pKa = 8.11DD28 pKa = 5.32HH29 pKa = 7.29DD30 pKa = 5.08VSTVDD35 pKa = 3.83SNNMDD40 pKa = 3.38VPSKK44 pKa = 10.83VQIEE48 pKa = 3.94MDD50 pKa = 3.36INTKK54 pKa = 9.2LVKK57 pKa = 9.79EE58 pKa = 4.59KK59 pKa = 11.31YY60 pKa = 9.73PIADD64 pKa = 2.87VWDD67 pKa = 3.47II68 pKa = 3.77

Molecular weight: 8.07 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0L7LWE4|A0A0L7LWE4_PLAF4 Uncharacterized protein OS=Plasmodium falciparum (isolate Dd2) OX=57267 GN=PFDG_00407 PE=4 SV=1
MM1 pKa = 7.53LVTLRR6 pKa = 11.84PILLTLRR13 pKa = 11.84PTLVTIRR20 pKa = 11.84PNLRR24 pKa = 11.84PTSVNPKK31 pKa = 9.16PILVILGPILLHH43 pKa = 5.57VRR45 pKa = 11.84PTFVIIGPILVILVPILVTLRR66 pKa = 11.84TKK68 pKa = 10.72LVIRR72 pKa = 11.84GPILVTLRR80 pKa = 11.84PKK82 pKa = 10.38LVNLRR87 pKa = 11.84LTFLL91 pKa = 4.03

Molecular weight: 10.18 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5132

0

5132

3041645

10

10240

592.7

69.84

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

1.959 ± 0.03

1.756 ± 0.019

6.562 ± 0.035

7.131 ± 0.074

4.216 ± 0.03

2.889 ± 0.036

2.445 ± 0.018

9.111 ± 0.046

11.539 ± 0.055

7.485 ± 0.043

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.269 ± 0.017

14.452 ± 0.125

2.077 ± 0.027

2.788 ± 0.021

2.692 ± 0.021

6.467 ± 0.033

4.156 ± 0.026

3.866 ± 0.041

0.497 ± 0.011

5.641 ± 0.033
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski