Amino acid dipepetide frequency for Bemisia-associated genomovirus AdDF

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.284AlaAla: 3.284 ± 0.11
0.0AlaCys: 0.0 ± 0.0
4.926AlaAsp: 4.926 ± 0.952
4.926AlaGlu: 4.926 ± 3.185
3.284AlaPhe: 3.284 ± 0.11
4.926AlaGly: 4.926 ± 3.515
0.0AlaHis: 0.0 ± 0.0
3.284AlaIle: 3.284 ± 2.123
4.926AlaLys: 4.926 ± 1.282
1.642AlaLeu: 1.642 ± 1.172
0.0AlaMet: 0.0 ± 0.0
3.284AlaAsn: 3.284 ± 0.11
0.0AlaPro: 0.0 ± 0.0
4.926AlaGln: 4.926 ± 0.952
11.494AlaArg: 11.494 ± 0.732
6.568AlaSer: 6.568 ± 2.453
6.568AlaThr: 6.568 ± 2.453
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
6.568CysAla: 6.568 ± 0.22
0.0CysCys: 0.0 ± 0.0
1.642CysAsp: 1.642 ± 1.062
0.0CysGlu: 0.0 ± 0.0
3.284CysPhe: 3.284 ± 0.11
1.642CysGly: 1.642 ± 1.062
0.0CysHis: 0.0 ± 0.0
3.284CysIle: 3.284 ± 2.123
0.0CysLys: 0.0 ± 0.0
1.642CysLeu: 1.642 ± 1.062
0.0CysMet: 0.0 ± 0.0
1.642CysAsn: 1.642 ± 1.062
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.568AspAla: 6.568 ± 2.013
1.642AspCys: 1.642 ± 1.062
8.21AspAsp: 8.21 ± 5.308
1.642AspGlu: 1.642 ± 1.172
3.284AspPhe: 3.284 ± 0.11
6.568AspGly: 6.568 ± 2.013
0.0AspHis: 0.0 ± 0.0
4.926AspIle: 4.926 ± 3.185
1.642AspLys: 1.642 ± 1.062
3.284AspLeu: 3.284 ± 0.11
3.284AspMet: 3.284 ± 2.123
4.926AspAsn: 4.926 ± 3.515
6.568AspPro: 6.568 ± 4.246
1.642AspGln: 1.642 ± 1.172
1.642AspArg: 1.642 ± 1.172
4.926AspSer: 4.926 ± 0.952
4.926AspThr: 4.926 ± 1.282
1.642AspVal: 1.642 ± 1.062
6.568AspTrp: 6.568 ± 2.013
6.568AspTyr: 6.568 ± 2.013
0.0AspXaa: 0.0 ± 0.0
Glu
3.284GluAla: 3.284 ± 2.343
1.642GluCys: 1.642 ± 1.062
1.642GluAsp: 1.642 ± 1.062
3.284GluGlu: 3.284 ± 2.123
0.0GluPhe: 0.0 ± 0.0
1.642GluGly: 1.642 ± 1.062
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
6.568GluLys: 6.568 ± 0.22
6.568GluLeu: 6.568 ± 4.246
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
1.642GluArg: 1.642 ± 1.062
8.21GluSer: 8.21 ± 1.392
3.284GluThr: 3.284 ± 0.11
0.0GluVal: 0.0 ± 0.0
1.642GluTrp: 1.642 ± 1.062
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.642PheAla: 1.642 ± 1.062
0.0PheCys: 0.0 ± 0.0
8.21PheAsp: 8.21 ± 5.308
1.642PheGlu: 1.642 ± 1.062
4.926PhePhe: 4.926 ± 3.185
3.284PheGly: 3.284 ± 2.123
0.0PheHis: 0.0 ± 0.0
1.642PheIle: 1.642 ± 1.172
3.284PheLys: 3.284 ± 2.343
1.642PheLeu: 1.642 ± 1.172
1.642PheMet: 1.642 ± 1.062
0.0PheAsn: 0.0 ± 0.0
3.284PhePro: 3.284 ± 0.11
3.284PheGln: 3.284 ± 2.123
3.284PheArg: 3.284 ± 0.11
1.642PheSer: 1.642 ± 1.172
6.568PheThr: 6.568 ± 2.453
1.642PheVal: 1.642 ± 1.062
3.284PheTrp: 3.284 ± 2.123
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.284GlyAla: 3.284 ± 2.123
0.0GlyCys: 0.0 ± 0.0
4.926GlyAsp: 4.926 ± 0.952
3.284GlyGlu: 3.284 ± 0.11
0.0GlyPhe: 0.0 ± 0.0
9.852GlyGly: 9.852 ± 6.37
1.642GlyHis: 1.642 ± 1.062
1.642GlyIle: 1.642 ± 1.062
4.926GlyLys: 4.926 ± 3.185
9.852GlyLeu: 9.852 ± 4.136
1.642GlyMet: 1.642 ± 1.172
6.568GlyAsn: 6.568 ± 2.453
4.926GlyPro: 4.926 ± 0.952
1.642GlyGln: 1.642 ± 1.062
13.136GlyArg: 13.136 ± 1.793
0.0GlySer: 0.0 ± 0.0
4.926GlyThr: 4.926 ± 1.282
6.568GlyVal: 6.568 ± 0.22
1.642GlyTrp: 1.642 ± 1.172
3.284GlyTyr: 3.284 ± 2.343
0.0GlyXaa: 0.0 ± 0.0
His
3.284HisAla: 3.284 ± 0.11
0.0HisCys: 0.0 ± 0.0
3.284HisAsp: 3.284 ± 2.123
1.642HisGlu: 1.642 ± 1.172
1.642HisPhe: 1.642 ± 1.062
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.642HisLys: 1.642 ± 1.172
1.642HisLeu: 1.642 ± 1.062
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.642HisPro: 1.642 ± 1.062
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.642HisSer: 1.642 ± 1.172
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
1.642HisTrp: 1.642 ± 1.172
1.642HisTyr: 1.642 ± 1.062
0.0HisXaa: 0.0 ± 0.0
Ile
3.284IleAla: 3.284 ± 0.11
3.284IleCys: 3.284 ± 0.11
1.642IleAsp: 1.642 ± 1.062
0.0IleGlu: 0.0 ± 0.0
3.284IlePhe: 3.284 ± 2.123
0.0IleGly: 0.0 ± 0.0
1.642IleHis: 1.642 ± 1.062
0.0IleIle: 0.0 ± 0.0
6.568IleLys: 6.568 ± 2.013
4.926IleLeu: 4.926 ± 1.282
0.0IleMet: 0.0 ± 0.0
4.926IleAsn: 4.926 ± 3.515
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
0.0IleArg: 0.0 ± 0.0
0.0IleSer: 0.0 ± 0.0
4.926IleThr: 4.926 ± 3.515
3.284IleVal: 3.284 ± 2.123
1.642IleTrp: 1.642 ± 1.062
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.642LysAla: 1.642 ± 1.062
0.0LysCys: 0.0 ± 0.0
1.642LysAsp: 1.642 ± 1.062
3.284LysGlu: 3.284 ± 0.11
3.284LysPhe: 3.284 ± 2.123
4.926LysGly: 4.926 ± 1.282
1.642LysHis: 1.642 ± 1.172
1.642LysIle: 1.642 ± 1.172
3.284LysLys: 3.284 ± 0.11
0.0LysLeu: 0.0 ± 0.0
3.284LysMet: 3.284 ± 0.771
3.284LysAsn: 3.284 ± 0.11
1.642LysPro: 1.642 ± 1.062
3.284LysGln: 3.284 ± 0.11
0.0LysArg: 0.0 ± 0.0
0.0LysSer: 0.0 ± 0.0
3.284LysThr: 3.284 ± 2.123
1.642LysVal: 1.642 ± 1.172
0.0LysTrp: 0.0 ± 0.0
8.21LysTyr: 8.21 ± 3.075
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
0.0LeuCys: 0.0 ± 0.0
8.21LeuAsp: 8.21 ± 0.842
4.926LeuGlu: 4.926 ± 0.952
3.284LeuPhe: 3.284 ± 0.11
14.778LeuGly: 14.778 ± 5.088
1.642LeuHis: 1.642 ± 1.062
3.284LeuIle: 3.284 ± 2.123
3.284LeuLys: 3.284 ± 0.11
4.926LeuLeu: 4.926 ± 1.282
1.642LeuMet: 1.642 ± 1.172
1.642LeuAsn: 1.642 ± 1.172
1.642LeuPro: 1.642 ± 1.172
0.0LeuGln: 0.0 ± 0.0
3.284LeuArg: 3.284 ± 2.123
1.642LeuSer: 1.642 ± 1.062
8.21LeuThr: 8.21 ± 1.392
4.926LeuVal: 4.926 ± 0.952
1.642LeuTrp: 1.642 ± 1.172
1.642LeuTyr: 1.642 ± 1.172
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
1.642MetCys: 1.642 ± 1.062
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.642MetPhe: 1.642 ± 1.062
3.284MetGly: 3.284 ± 0.11
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
4.926MetLeu: 4.926 ± 3.515
1.642MetMet: 1.642 ± 1.172
1.642MetAsn: 1.642 ± 1.172
3.284MetPro: 3.284 ± 0.11
0.0MetGln: 0.0 ± 0.0
1.642MetArg: 1.642 ± 1.172
0.0MetSer: 0.0 ± 0.0
1.642MetThr: 1.642 ± 1.062
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.284MetTyr: 3.284 ± 0.11
0.0MetXaa: 0.0 ± 0.0
Asn
4.926AsnAla: 4.926 ± 1.282
1.642AsnCys: 1.642 ± 1.062
6.568AsnAsp: 6.568 ± 2.453
0.0AsnGlu: 0.0 ± 0.0
3.284AsnPhe: 3.284 ± 0.11
3.284AsnGly: 3.284 ± 2.343
3.284AsnHis: 3.284 ± 0.11
8.21AsnIle: 8.21 ± 3.625
0.0AsnLys: 0.0 ± 0.0
1.642AsnLeu: 1.642 ± 1.172
1.642AsnMet: 1.642 ± 1.172
6.568AsnAsn: 6.568 ± 0.22
0.0AsnPro: 0.0 ± 0.0
6.568AsnGln: 6.568 ± 4.687
3.284AsnArg: 3.284 ± 0.11
1.642AsnSer: 1.642 ± 1.172
1.642AsnThr: 1.642 ± 1.172
3.284AsnVal: 3.284 ± 0.11
1.642AsnTrp: 1.642 ± 1.172
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.284ProAla: 3.284 ± 0.11
0.0ProCys: 0.0 ± 0.0
4.926ProAsp: 4.926 ± 3.185
4.926ProGlu: 4.926 ± 0.952
1.642ProPhe: 1.642 ± 1.172
3.284ProGly: 3.284 ± 0.11
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
0.0ProLys: 0.0 ± 0.0
6.568ProLeu: 6.568 ± 2.013
3.284ProMet: 3.284 ± 2.343
1.642ProAsn: 1.642 ± 1.062
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
4.926ProArg: 4.926 ± 3.185
1.642ProSer: 1.642 ± 1.062
3.284ProThr: 3.284 ± 0.11
3.284ProVal: 3.284 ± 0.11
0.0ProTrp: 0.0 ± 0.0
1.642ProTyr: 1.642 ± 1.062
0.0ProXaa: 0.0 ± 0.0
Gln
1.642GlnAla: 1.642 ± 1.172
0.0GlnCys: 0.0 ± 0.0
3.284GlnAsp: 3.284 ± 0.11
0.0GlnGlu: 0.0 ± 0.0
1.642GlnPhe: 1.642 ± 1.172
3.284GlnGly: 3.284 ± 2.343
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
1.642GlnLeu: 1.642 ± 1.062
0.0GlnMet: 0.0 ± 0.796
1.642GlnAsn: 1.642 ± 1.172
1.642GlnPro: 1.642 ± 1.172
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
4.926GlnSer: 4.926 ± 0.952
1.642GlnThr: 1.642 ± 1.172
1.642GlnVal: 1.642 ± 1.062
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.284ArgAla: 3.284 ± 0.11
3.284ArgCys: 3.284 ± 2.123
4.926ArgAsp: 4.926 ± 1.282
6.568ArgGlu: 6.568 ± 2.013
1.642ArgPhe: 1.642 ± 1.062
8.21ArgGly: 8.21 ± 3.075
0.0ArgHis: 0.0 ± 0.0
3.284ArgIle: 3.284 ± 2.343
0.0ArgLys: 0.0 ± 0.0
1.642ArgLeu: 1.642 ± 1.172
0.0ArgMet: 0.0 ± 0.0
4.926ArgAsn: 4.926 ± 1.282
8.21ArgPro: 8.21 ± 0.842
0.0ArgGln: 0.0 ± 0.0
21.346ArgArg: 21.346 ± 10.765
6.568ArgSer: 6.568 ± 0.22
4.926ArgThr: 4.926 ± 1.282
6.568ArgVal: 6.568 ± 2.453
0.0ArgTrp: 0.0 ± 0.0
4.926ArgTyr: 4.926 ± 1.282
0.0ArgXaa: 0.0 ± 0.0
Ser
3.284SerAla: 3.284 ± 2.343
0.0SerCys: 0.0 ± 0.0
3.284SerAsp: 3.284 ± 0.11
1.642SerGlu: 1.642 ± 1.172
0.0SerPhe: 0.0 ± 0.0
3.284SerGly: 3.284 ± 2.343
1.642SerHis: 1.642 ± 1.172
3.284SerIle: 3.284 ± 0.11
1.642SerLys: 1.642 ± 1.062
4.926SerLeu: 4.926 ± 0.952
1.642SerMet: 1.642 ± 1.062
4.926SerAsn: 4.926 ± 3.515
1.642SerPro: 1.642 ± 1.062
0.0SerGln: 0.0 ± 0.0
4.926SerArg: 4.926 ± 0.952
4.926SerSer: 4.926 ± 1.282
6.568SerThr: 6.568 ± 4.687
1.642SerVal: 1.642 ± 1.172
1.642SerTrp: 1.642 ± 1.172
3.284SerTyr: 3.284 ± 2.123
0.0SerXaa: 0.0 ± 0.0
Thr
6.568ThrAla: 6.568 ± 4.687
1.642ThrCys: 1.642 ± 1.172
3.284ThrAsp: 3.284 ± 2.123
0.0ThrGlu: 0.0 ± 0.0
3.284ThrPhe: 3.284 ± 2.123
1.642ThrGly: 1.642 ± 1.062
1.642ThrHis: 1.642 ± 1.062
3.284ThrIle: 3.284 ± 2.343
3.284ThrLys: 3.284 ± 0.11
4.926ThrLeu: 4.926 ± 1.282
1.642ThrMet: 1.642 ± 1.172
4.926ThrAsn: 4.926 ± 3.515
3.284ThrPro: 3.284 ± 0.11
3.284ThrGln: 3.284 ± 2.343
9.852ThrArg: 9.852 ± 7.03
4.926ThrSer: 4.926 ± 3.515
9.852ThrThr: 9.852 ± 4.797
3.284ThrVal: 3.284 ± 0.11
3.284ThrTrp: 3.284 ± 2.123
1.642ThrTyr: 1.642 ± 1.062
0.0ThrXaa: 0.0 ± 0.0
Val
1.642ValAla: 1.642 ± 1.172
0.0ValCys: 0.0 ± 0.0
4.926ValAsp: 4.926 ± 1.282
0.0ValGlu: 0.0 ± 0.0
4.926ValPhe: 4.926 ± 0.952
6.568ValGly: 6.568 ± 2.013
0.0ValHis: 0.0 ± 0.0
1.642ValIle: 1.642 ± 1.062
0.0ValLys: 0.0 ± 0.0
3.284ValLeu: 3.284 ± 0.11
0.0ValMet: 0.0 ± 0.0
4.926ValAsn: 4.926 ± 0.952
3.284ValPro: 3.284 ± 0.11
0.0ValGln: 0.0 ± 0.0
4.926ValArg: 4.926 ± 1.282
3.284ValSer: 3.284 ± 2.343
3.284ValThr: 3.284 ± 0.11
1.642ValVal: 1.642 ± 1.172
0.0ValTrp: 0.0 ± 0.0
1.642ValTyr: 1.642 ± 1.172
0.0ValXaa: 0.0 ± 0.0
Trp
1.642TrpAla: 1.642 ± 1.062
4.926TrpCys: 4.926 ± 0.952
0.0TrpAsp: 0.0 ± 0.0
1.642TrpGlu: 1.642 ± 1.062
1.642TrpPhe: 1.642 ± 1.172
1.642TrpGly: 1.642 ± 1.062
3.284TrpHis: 3.284 ± 2.343
0.0TrpIle: 0.0 ± 0.0
1.642TrpLys: 1.642 ± 1.062
3.284TrpLeu: 3.284 ± 2.123
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
3.284TrpArg: 3.284 ± 0.11
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.642TrpVal: 1.642 ± 1.172
0.0TrpTrp: 0.0 ± 0.0
1.642TrpTyr: 1.642 ± 1.172
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.926TyrAla: 4.926 ± 3.185
0.0TyrCys: 0.0 ± 0.0
4.926TyrAsp: 4.926 ± 1.282
0.0TyrGlu: 0.0 ± 0.0
4.926TyrPhe: 4.926 ± 0.952
1.642TyrGly: 1.642 ± 1.062
3.284TyrHis: 3.284 ± 2.123
0.0TyrIle: 0.0 ± 0.0
3.284TyrLys: 3.284 ± 2.123
1.642TyrLeu: 1.642 ± 1.062
1.642TyrMet: 1.642 ± 1.172
1.642TyrAsn: 1.642 ± 1.172
3.284TyrPro: 3.284 ± 2.123
0.0TyrGln: 0.0 ± 0.0
1.642TyrArg: 1.642 ± 1.172
1.642TyrSer: 1.642 ± 1.172
0.0TyrThr: 0.0 ± 0.0
3.284TyrVal: 3.284 ± 2.343
1.642TyrTrp: 1.642 ± 1.172
3.284TyrTyr: 3.284 ± 0.11
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (610 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski