Amino acid dipepetide frequency for Rubripirellula tenax

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.178AlaAla: 11.178 ± 0.099	1.1AlaCys: 1.1 ± 0.023	6.747AlaAsp: 6.747 ± 0.065	5.814AlaGlu: 5.814 ± 0.067	3.394AlaPhe: 3.394 ± 0.039	7.899AlaGly: 7.899 ± 0.081	1.482AlaHis: 1.482 ± 0.029	6.507AlaIle: 6.507 ± 0.057	4.15AlaLys: 4.15 ± 0.053	7.208AlaLeu: 7.208 ± 0.06	3.136AlaMet: 3.136 ± 0.049	3.413AlaAsn: 3.413 ± 0.044	3.729AlaPro: 3.729 ± 0.048	2.8AlaGln: 2.8 ± 0.036	5.021AlaArg: 5.021 ± 0.059	7.214AlaSer: 7.214 ± 0.07	6.492AlaThr: 6.492 ± 0.074	7.036AlaVal: 7.036 ± 0.062	1.334AlaTrp: 1.334 ± 0.027	2.034AlaTyr: 2.034 ± 0.03	0.001AlaXaa: 0.001 ± 0.001
Cys	0.712CysAla: 0.712 ± 0.018	0.206CysCys: 0.206 ± 0.01	0.786CysAsp: 0.786 ± 0.025	0.691CysGlu: 0.691 ± 0.018	0.446CysPhe: 0.446 ± 0.012	1.067CysGly: 1.067 ± 0.033	0.418CysHis: 0.418 ± 0.019	0.461CysIle: 0.461 ± 0.014	0.296CysLys: 0.296 ± 0.014	1.002CysLeu: 1.002 ± 0.021	0.189CysMet: 0.189 ± 0.009	0.314CysAsn: 0.314 ± 0.013	0.532CysPro: 0.532 ± 0.016	0.384CysGln: 0.384 ± 0.013	0.77CysArg: 0.77 ± 0.019	0.647CysSer: 0.647 ± 0.021	0.486CysThr: 0.486 ± 0.016	0.868CysVal: 0.868 ± 0.022	0.165CysTrp: 0.165 ± 0.01	0.287CysTyr: 0.287 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.124AspAla: 7.124 ± 0.076	0.605AspCys: 0.605 ± 0.016	4.916AspAsp: 4.916 ± 0.063	4.49AspGlu: 4.49 ± 0.052	2.611AspPhe: 2.611 ± 0.036	6.227AspGly: 6.227 ± 0.094	1.551AspHis: 1.551 ± 0.027	2.669AspIle: 2.669 ± 0.04	1.796AspLys: 1.796 ± 0.034	5.777AspLeu: 5.777 ± 0.055	1.104AspMet: 1.104 ± 0.023	1.88AspAsn: 1.88 ± 0.036	3.801AspPro: 3.801 ± 0.046	2.682AspGln: 2.682 ± 0.036	4.862AspArg: 4.862 ± 0.05	4.274AspSer: 4.274 ± 0.046	2.944AspThr: 2.944 ± 0.056	4.982AspVal: 4.982 ± 0.06	1.161AspTrp: 1.161 ± 0.024	1.567AspTyr: 1.567 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	5.345GluAla: 5.345 ± 0.063	0.461GluCys: 0.461 ± 0.015	2.7GluAsp: 2.7 ± 0.042	2.603GluGlu: 2.603 ± 0.052	2.208GluPhe: 2.208 ± 0.031	3.329GluGly: 3.329 ± 0.043	1.246GluHis: 1.246 ± 0.025	3.318GluIle: 3.318 ± 0.035	2.369GluLys: 2.369 ± 0.04	6.065GluLeu: 6.065 ± 0.066	1.563GluMet: 1.563 ± 0.03	1.999GluAsn: 1.999 ± 0.03	2.612GluPro: 2.612 ± 0.038	2.41GluGln: 2.41 ± 0.039	3.543GluArg: 3.543 ± 0.056	4.703GluSer: 4.703 ± 0.047	3.806GluThr: 3.806 ± 0.041	4.009GluVal: 4.009 ± 0.049	0.635GluTrp: 0.635 ± 0.018	1.241GluTyr: 1.241 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.132PheAla: 4.132 ± 0.045	0.478PheCys: 0.478 ± 0.016	3.236PheAsp: 3.236 ± 0.046	2.205PheGlu: 2.205 ± 0.03	1.523PhePhe: 1.523 ± 0.026	3.504PheGly: 3.504 ± 0.041	0.801PheHis: 0.801 ± 0.018	1.479PheIle: 1.479 ± 0.027	1.025PheLys: 1.025 ± 0.022	3.208PheLeu: 3.208 ± 0.042	0.649PheMet: 0.649 ± 0.018	1.226PheAsn: 1.226 ± 0.026	1.587PhePro: 1.587 ± 0.026	1.311PheGln: 1.311 ± 0.02	2.406PheArg: 2.406 ± 0.031	2.401PheSer: 2.401 ± 0.033	2.151PheThr: 2.151 ± 0.042	3.034PheVal: 3.034 ± 0.041	0.544PheTrp: 0.544 ± 0.017	0.946PheTyr: 0.946 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	5.817GlyAla: 5.817 ± 0.068	1.001GlyCys: 1.001 ± 0.032	5.43GlyAsp: 5.43 ± 0.074	4.424GlyGlu: 4.424 ± 0.051	3.224GlyPhe: 3.224 ± 0.042	7.08GlyGly: 7.08 ± 0.118	1.681GlyHis: 1.681 ± 0.028	4.077GlyIle: 4.077 ± 0.046	3.527GlyLys: 3.527 ± 0.048	6.745GlyLeu: 6.745 ± 0.057	2.006GlyMet: 2.006 ± 0.042	3.067GlyAsn: 3.067 ± 0.072	3.115GlyPro: 3.115 ± 0.04	2.842GlyGln: 2.842 ± 0.038	5.071GlyArg: 5.071 ± 0.048	5.387GlySer: 5.387 ± 0.073	4.83GlyThr: 4.83 ± 0.097	5.545GlyVal: 5.545 ± 0.058	1.276GlyTrp: 1.276 ± 0.025	2.138GlyTyr: 2.138 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	1.987HisAla: 1.987 ± 0.031	0.332HisCys: 0.332 ± 0.013	1.388HisAsp: 1.388 ± 0.026	1.106HisGlu: 1.106 ± 0.023	0.916HisPhe: 0.916 ± 0.022	1.719HisGly: 1.719 ± 0.033	0.691HisHis: 0.691 ± 0.018	0.82HisIle: 0.82 ± 0.019	0.517HisLys: 0.517 ± 0.016	2.051HisLeu: 2.051 ± 0.032	0.374HisMet: 0.374 ± 0.012	0.607HisAsn: 0.607 ± 0.017	1.355HisPro: 1.355 ± 0.027	0.877HisGln: 0.877 ± 0.019	1.708HisArg: 1.708 ± 0.035	1.352HisSer: 1.352 ± 0.024	0.934HisThr: 0.934 ± 0.021	1.572HisVal: 1.572 ± 0.025	0.439HisTrp: 0.439 ± 0.014	0.594HisTyr: 0.594 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	6.69IleAla: 6.69 ± 0.063	0.578IleCys: 0.578 ± 0.018	4.728IleAsp: 4.728 ± 0.052	4.16IleGlu: 4.16 ± 0.044	1.465IlePhe: 1.465 ± 0.026	4.646IleGly: 4.646 ± 0.051	1.139IleHis: 1.139 ± 0.024	1.912IleIle: 1.912 ± 0.035	1.555IleLys: 1.555 ± 0.028	3.806IleLeu: 3.806 ± 0.042	0.731IleMet: 0.731 ± 0.017	1.735IleAsn: 1.735 ± 0.039	2.463IlePro: 2.463 ± 0.032	1.835IleGln: 1.835 ± 0.028	3.684IleArg: 3.684 ± 0.038	3.255IleSer: 3.255 ± 0.036	2.856IleThr: 2.856 ± 0.052	4.274IleVal: 4.274 ± 0.041	0.569IleTrp: 0.569 ± 0.016	1.166IleTyr: 1.166 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	3.008LysAla: 3.008 ± 0.042	0.309LysCys: 0.309 ± 0.012	1.735LysAsp: 1.735 ± 0.033	1.717LysGlu: 1.717 ± 0.03	1.264LysPhe: 1.264 ± 0.023	1.972LysGly: 1.972 ± 0.038	0.846LysHis: 0.846 ± 0.021	1.931LysIle: 1.931 ± 0.032	1.707LysLys: 1.707 ± 0.039	3.625LysLeu: 3.625 ± 0.05	0.944LysMet: 0.944 ± 0.022	1.216LysAsn: 1.216 ± 0.025	2.242LysPro: 2.242 ± 0.04	1.527LysGln: 1.527 ± 0.028	2.569LysArg: 2.569 ± 0.038	2.589LysSer: 2.589 ± 0.041	2.29LysThr: 2.29 ± 0.04	2.286LysVal: 2.286 ± 0.039	0.587LysTrp: 0.587 ± 0.017	0.861LysTyr: 0.861 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	10.179LeuAla: 10.179 ± 0.083	1.018LeuCys: 1.018 ± 0.025	5.93LeuAsp: 5.93 ± 0.051	4.712LeuGlu: 4.712 ± 0.059	3.204LeuPhe: 3.204 ± 0.039	6.737LeuGly: 6.737 ± 0.053	1.834LeuHis: 1.834 ± 0.031	4.748LeuIle: 4.748 ± 0.05	3.221LeuLys: 3.221 ± 0.049	8.319LeuLeu: 8.319 ± 0.083	2.198LeuMet: 2.198 ± 0.034	2.731LeuAsn: 2.731 ± 0.04	5.005LeuPro: 5.005 ± 0.055	3.135LeuGln: 3.135 ± 0.039	6.065LeuArg: 6.065 ± 0.066	6.475LeuSer: 6.475 ± 0.055	5.386LeuThr: 5.386 ± 0.057	6.873LeuVal: 6.873 ± 0.059	1.108LeuTrp: 1.108 ± 0.025	1.82LeuTyr: 1.82 ± 0.029	0.001LeuXaa: 0.001 ± 0.001
Met	2.335MetAla: 2.335 ± 0.034	0.209MetCys: 0.209 ± 0.009	1.191MetAsp: 1.191 ± 0.026	1.068MetGlu: 1.068 ± 0.023	0.814MetPhe: 0.814 ± 0.022	1.57MetGly: 1.57 ± 0.03	0.519MetHis: 0.519 ± 0.014	1.439MetIle: 1.439 ± 0.026	1.113MetLys: 1.113 ± 0.024	2.491MetLeu: 2.491 ± 0.04	0.717MetMet: 0.717 ± 0.02	0.985MetAsn: 0.985 ± 0.02	1.47MetPro: 1.47 ± 0.029	0.925MetGln: 0.925 ± 0.021	1.543MetArg: 1.543 ± 0.027	1.684MetSer: 1.684 ± 0.032	1.691MetThr: 1.691 ± 0.028	1.676MetVal: 1.676 ± 0.03	0.255MetTrp: 0.255 ± 0.011	0.393MetTyr: 0.393 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.235AsnAla: 3.235 ± 0.049	0.312AsnCys: 0.312 ± 0.013	2.37AsnAsp: 2.37 ± 0.05	2.002AsnGlu: 2.002 ± 0.028	1.25AsnPhe: 1.25 ± 0.023	2.885AsnGly: 2.885 ± 0.059	0.811AsnHis: 0.811 ± 0.018	1.418AsnIle: 1.418 ± 0.028	0.843AsnLys: 0.843 ± 0.02	2.898AsnLeu: 2.898 ± 0.039	0.561AsnMet: 0.561 ± 0.014	1.169AsnAsn: 1.169 ± 0.031	2.051AsnPro: 2.051 ± 0.035	1.465AsnGln: 1.465 ± 0.028	2.47AsnArg: 2.47 ± 0.032	2.02AsnSer: 2.02 ± 0.039	1.718AsnThr: 1.718 ± 0.039	2.673AsnVal: 2.673 ± 0.042	0.498AsnTrp: 0.498 ± 0.015	0.853AsnTyr: 0.853 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	4.751ProAla: 4.751 ± 0.051	0.368ProCys: 0.368 ± 0.015	3.522ProAsp: 3.522 ± 0.042	3.187ProGlu: 3.187 ± 0.046	1.785ProPhe: 1.785 ± 0.031	3.786ProGly: 3.786 ± 0.054	1.0ProHis: 1.0 ± 0.02	3.01ProIle: 3.01 ± 0.037	1.909ProLys: 1.909 ± 0.034	4.111ProLeu: 4.111 ± 0.043	1.38ProMet: 1.38 ± 0.029	1.953ProAsn: 1.953 ± 0.031	2.661ProPro: 2.661 ± 0.051	1.575ProGln: 1.575 ± 0.027	2.586ProArg: 2.586 ± 0.035	3.841ProSer: 3.841 ± 0.045	3.484ProThr: 3.484 ± 0.047	3.631ProVal: 3.631 ± 0.044	0.735ProTrp: 0.735 ± 0.018	1.118ProTyr: 1.118 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.289GlnAla: 3.289 ± 0.045	0.413GlnCys: 0.413 ± 0.015	1.578GlnAsp: 1.578 ± 0.026	1.437GlnGlu: 1.437 ± 0.028	1.553GlnPhe: 1.553 ± 0.028	2.1GlnGly: 2.1 ± 0.036	0.814GlnHis: 0.814 ± 0.018	2.15GlnIle: 2.15 ± 0.032	1.161GlnLys: 1.161 ± 0.021	3.774GlnLeu: 3.774 ± 0.042	0.95GlnMet: 0.95 ± 0.019	1.135GlnAsn: 1.135 ± 0.022	2.034GlnPro: 2.034 ± 0.034	1.647GlnGln: 1.647 ± 0.032	2.759GlnArg: 2.759 ± 0.034	3.026GlnSer: 3.026 ± 0.037	2.519GlnThr: 2.519 ± 0.04	2.533GlnVal: 2.533 ± 0.035	0.731GlnTrp: 0.731 ± 0.019	0.899GlnTyr: 0.899 ± 0.021	0.001GlnXaa: 0.001 ± 0.001
Arg	4.772ArgAla: 4.772 ± 0.052	0.759ArgCys: 0.759 ± 0.019	4.085ArgAsp: 4.085 ± 0.045	3.57ArgGlu: 3.57 ± 0.051	2.982ArgPhe: 2.982 ± 0.035	4.359ArgGly: 4.359 ± 0.044	1.45ArgHis: 1.45 ± 0.029	3.817ArgIle: 3.817 ± 0.04	2.302ArgLys: 2.302 ± 0.039	6.877ArgLeu: 6.877 ± 0.061	1.907ArgMet: 1.907 ± 0.03	2.125ArgAsn: 2.125 ± 0.029	3.076ArgPro: 3.076 ± 0.049	2.602ArgGln: 2.602 ± 0.033	5.21ArgArg: 5.21 ± 0.07	4.633ArgSer: 4.633 ± 0.053	3.431ArgThr: 3.431 ± 0.047	4.733ArgVal: 4.733 ± 0.048	1.257ArgTrp: 1.257 ± 0.027	1.839ArgTyr: 1.839 ± 0.031	0.001ArgXaa: 0.001 ± 0.001
Ser	6.127SerAla: 6.127 ± 0.057	0.622SerCys: 0.622 ± 0.018	4.832SerAsp: 4.832 ± 0.046	3.72SerGlu: 3.72 ± 0.045	2.546SerPhe: 2.546 ± 0.032	6.104SerGly: 6.104 ± 0.07	1.445SerHis: 1.445 ± 0.024	4.14SerIle: 4.14 ± 0.046	2.351SerLys: 2.351 ± 0.038	6.828SerLeu: 6.828 ± 0.064	1.756SerMet: 1.756 ± 0.031	2.312SerAsn: 2.312 ± 0.038	3.838SerPro: 3.838 ± 0.049	2.469SerGln: 2.469 ± 0.032	4.31SerArg: 4.31 ± 0.049	4.823SerSer: 4.823 ± 0.055	4.05SerThr: 4.05 ± 0.061	5.32SerVal: 5.32 ± 0.061	0.863SerTrp: 0.863 ± 0.019	1.395SerTyr: 1.395 ± 0.029	0.001SerXaa: 0.001 ± 0.001
Thr	5.689ThrAla: 5.689 ± 0.077	0.541ThrCys: 0.541 ± 0.016	3.963ThrAsp: 3.963 ± 0.06	3.1ThrGlu: 3.1 ± 0.044	2.31ThrPhe: 2.31 ± 0.048	4.849ThrGly: 4.849 ± 0.074	1.161ThrHis: 1.161 ± 0.024	3.652ThrIle: 3.652 ± 0.062	1.934ThrLys: 1.934 ± 0.033	5.756ThrLeu: 5.756 ± 0.064	1.317ThrMet: 1.317 ± 0.026	2.051ThrAsn: 2.051 ± 0.052	3.399ThrPro: 3.399 ± 0.043	1.922ThrGln: 1.922 ± 0.032	3.402ThrArg: 3.402 ± 0.046	4.073ThrSer: 4.073 ± 0.059	3.741ThrThr: 3.741 ± 0.071	4.563ThrVal: 4.563 ± 0.07	0.812ThrTrp: 0.812 ± 0.02	1.395ThrTyr: 1.395 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	8.111ValAla: 8.111 ± 0.077	0.916ValCys: 0.916 ± 0.024	5.408ValAsp: 5.408 ± 0.054	4.187ValGlu: 4.187 ± 0.04	2.704ValPhe: 2.704 ± 0.036	5.693ValGly: 5.693 ± 0.064	1.461ValHis: 1.461 ± 0.026	3.952ValIle: 3.952 ± 0.046	2.151ValLys: 2.151 ± 0.033	6.335ValLeu: 6.335 ± 0.05	1.754ValMet: 1.754 ± 0.028	2.296ValAsn: 2.296 ± 0.046	3.572ValPro: 3.572 ± 0.048	2.333ValGln: 2.333 ± 0.031	4.858ValArg: 4.858 ± 0.046	5.03ValSer: 5.03 ± 0.053	4.721ValThr: 4.721 ± 0.082	6.008ValVal: 6.008 ± 0.063	1.026ValTrp: 1.026 ± 0.023	1.625ValTyr: 1.625 ± 0.025	0.001ValXaa: 0.001 ± 0.001
Trp	1.075TrpAla: 1.075 ± 0.023	0.197TrpCys: 0.197 ± 0.01	0.819TrpAsp: 0.819 ± 0.017	0.609TrpGlu: 0.609 ± 0.018	0.605TrpPhe: 0.605 ± 0.018	0.873TrpGly: 0.873 ± 0.019	0.402TrpHis: 0.402 ± 0.015	0.971TrpIle: 0.971 ± 0.022	0.669TrpLys: 0.669 ± 0.021	1.594TrpLeu: 1.594 ± 0.03	0.481TrpMet: 0.481 ± 0.016	0.595TrpAsn: 0.595 ± 0.016	0.699TrpPro: 0.699 ± 0.022	0.706TrpGln: 0.706 ± 0.019	0.935TrpArg: 0.935 ± 0.022	0.988TrpSer: 0.988 ± 0.02	0.91TrpThr: 0.91 ± 0.023	0.917TrpVal: 0.917 ± 0.022	0.275TrpTrp: 0.275 ± 0.013	0.341TrpTyr: 0.341 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.131TyrAla: 2.131 ± 0.031	0.302TyrCys: 0.302 ± 0.014	1.66TyrAsp: 1.66 ± 0.042	1.361TyrGlu: 1.361 ± 0.025	1.044TyrPhe: 1.044 ± 0.021	1.882TyrGly: 1.882 ± 0.031	0.588TyrHis: 0.588 ± 0.016	0.777TyrIle: 0.777 ± 0.019	0.629TyrLys: 0.629 ± 0.018	2.226TyrLeu: 2.226 ± 0.035	0.373TyrMet: 0.373 ± 0.014	0.694TyrAsn: 0.694 ± 0.019	1.152TyrPro: 1.152 ± 0.024	1.055TyrGln: 1.055 ± 0.024	2.012TyrArg: 2.012 ± 0.029	1.435TyrSer: 1.435 ± 0.027	1.189TyrThr: 1.189 ± 0.035	1.609TyrVal: 1.609 ± 0.028	0.393TyrTrp: 0.393 ± 0.016	0.668TyrTyr: 0.668 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.001	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.002XaaArg: 0.002 ± 0.001	0.001XaaSer: 0.001 ± 0.001	0.001XaaThr: 0.001 ± 0.001	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 6268 proteins (2351484 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---