Amino acid dipepetide frequency for Croceibacter atlanticus (strain ATCC BAA-628 / HTCC2559 / KCTC 12090)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.906AlaAla: 3.906 ± 0.098	0.535AlaCys: 0.535 ± 0.026	3.28AlaAsp: 3.28 ± 0.087	4.18AlaGlu: 4.18 ± 0.085	3.339AlaPhe: 3.339 ± 0.063	4.09AlaGly: 4.09 ± 0.133	1.13AlaHis: 1.13 ± 0.038	5.56AlaIle: 5.56 ± 0.082	4.777AlaLys: 4.777 ± 0.099	6.431AlaLeu: 6.431 ± 0.096	1.595AlaMet: 1.595 ± 0.047	3.751AlaAsn: 3.751 ± 0.073	1.913AlaPro: 1.913 ± 0.061	2.535AlaGln: 2.535 ± 0.056	2.01AlaArg: 2.01 ± 0.052	4.45AlaSer: 4.45 ± 0.076	4.181AlaThr: 4.181 ± 0.13	4.227AlaVal: 4.227 ± 0.072	0.545AlaTrp: 0.545 ± 0.029	2.477AlaTyr: 2.477 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.452CysAla: 0.452 ± 0.027	0.085CysCys: 0.085 ± 0.009	0.439CysAsp: 0.439 ± 0.032	0.466CysGlu: 0.466 ± 0.026	0.388CysPhe: 0.388 ± 0.019	0.6CysGly: 0.6 ± 0.032	0.166CysHis: 0.166 ± 0.016	0.588CysIle: 0.588 ± 0.026	0.432CysLys: 0.432 ± 0.023	0.686CysLeu: 0.686 ± 0.029	0.116CysMet: 0.116 ± 0.01	0.43CysAsn: 0.43 ± 0.028	0.308CysPro: 0.308 ± 0.021	0.203CysGln: 0.203 ± 0.024	0.164CysArg: 0.164 ± 0.014	0.539CysSer: 0.539 ± 0.028	0.402CysThr: 0.402 ± 0.026	0.45CysVal: 0.45 ± 0.022	0.061CysTrp: 0.061 ± 0.009	0.277CysTyr: 0.277 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.342AspAla: 4.342 ± 0.119	0.428AspCys: 0.428 ± 0.023	3.39AspAsp: 3.39 ± 0.171	3.929AspGlu: 3.929 ± 0.094	3.416AspPhe: 3.416 ± 0.064	4.163AspGly: 4.163 ± 0.204	0.935AspHis: 0.935 ± 0.038	4.631AspIle: 4.631 ± 0.079	3.891AspLys: 3.891 ± 0.092	5.209AspLeu: 5.209 ± 0.089	1.219AspMet: 1.219 ± 0.039	3.713AspAsn: 3.713 ± 0.124	1.824AspPro: 1.824 ± 0.11	1.538AspGln: 1.538 ± 0.049	1.856AspArg: 1.856 ± 0.047	3.385AspSer: 3.385 ± 0.073	3.519AspThr: 3.519 ± 0.116	4.329AspVal: 4.329 ± 0.126	0.698AspTrp: 0.698 ± 0.03	2.887AspTyr: 2.887 ± 0.062	0.0AspXaa: 0.0 ± 0.0
Glu	4.624GluAla: 4.624 ± 0.088	0.325GluCys: 0.325 ± 0.026	4.876GluAsp: 4.876 ± 0.079	4.906GluGlu: 4.906 ± 0.101	3.152GluPhe: 3.152 ± 0.065	3.692GluGly: 3.692 ± 0.066	1.317GluHis: 1.317 ± 0.043	4.876GluIle: 4.876 ± 0.082	4.817GluLys: 4.817 ± 0.107	5.986GluLeu: 5.986 ± 0.101	1.441GluMet: 1.441 ± 0.041	4.326GluAsn: 4.326 ± 0.078	1.705GluPro: 1.705 ± 0.044	2.581GluGln: 2.581 ± 0.059	2.677GluArg: 2.677 ± 0.064	3.42GluSer: 3.42 ± 0.062	4.4GluThr: 4.4 ± 0.069	4.308GluVal: 4.308 ± 0.071	0.542GluTrp: 0.542 ± 0.026	2.179GluTyr: 2.179 ± 0.051	0.0GluXaa: 0.0 ± 0.0
Phe	2.838PheAla: 2.838 ± 0.063	0.388PheCys: 0.388 ± 0.028	2.903PheAsp: 2.903 ± 0.059	3.426PheGlu: 3.426 ± 0.079	2.495PhePhe: 2.495 ± 0.069	3.579PheGly: 3.579 ± 0.077	0.734PheHis: 0.734 ± 0.029	3.758PheIle: 3.758 ± 0.082	4.037PheLys: 4.037 ± 0.087	4.218PheLeu: 4.218 ± 0.094	0.972PheMet: 0.972 ± 0.035	3.542PheAsn: 3.542 ± 0.076	1.668PhePro: 1.668 ± 0.05	1.531PheGln: 1.531 ± 0.044	1.488PheArg: 1.488 ± 0.039	3.999PheSer: 3.999 ± 0.071	3.219PheThr: 3.219 ± 0.067	2.983PheVal: 2.983 ± 0.068	0.562PheTrp: 0.562 ± 0.023	2.112PheTyr: 2.112 ± 0.061	0.0PheXaa: 0.0 ± 0.0
Gly	4.203GlyAla: 4.203 ± 0.093	0.584GlyCys: 0.584 ± 0.029	3.721GlyAsp: 3.721 ± 0.139	3.664GlyGlu: 3.664 ± 0.069	3.576GlyPhe: 3.576 ± 0.073	4.58GlyGly: 4.58 ± 0.194	1.132GlyHis: 1.132 ± 0.042	5.119GlyIle: 5.119 ± 0.095	4.469GlyLys: 4.469 ± 0.09	5.682GlyLeu: 5.682 ± 0.094	1.515GlyMet: 1.515 ± 0.049	3.851GlyAsn: 3.851 ± 0.141	1.315GlyPro: 1.315 ± 0.042	1.974GlyGln: 1.974 ± 0.045	1.969GlyArg: 1.969 ± 0.061	4.168GlySer: 4.168 ± 0.109	4.246GlyThr: 4.246 ± 0.108	4.407GlyVal: 4.407 ± 0.092	0.69GlyTrp: 0.69 ± 0.031	2.748GlyTyr: 2.748 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	0.85HisAla: 0.85 ± 0.036	0.183HisCys: 0.183 ± 0.015	0.8HisAsp: 0.8 ± 0.032	0.847HisGlu: 0.847 ± 0.031	1.048HisPhe: 1.048 ± 0.04	0.96HisGly: 0.96 ± 0.037	0.465HisHis: 0.465 ± 0.025	1.496HisIle: 1.496 ± 0.043	1.255HisLys: 1.255 ± 0.044	1.817HisLeu: 1.817 ± 0.053	0.354HisMet: 0.354 ± 0.023	1.006HisAsn: 1.006 ± 0.038	0.847HisPro: 0.847 ± 0.033	0.725HisGln: 0.725 ± 0.03	0.64HisArg: 0.64 ± 0.025	1.022HisSer: 1.022 ± 0.033	0.982HisThr: 0.982 ± 0.04	0.919HisVal: 0.919 ± 0.039	0.202HisTrp: 0.202 ± 0.016	0.851HisTyr: 0.851 ± 0.035	0.0HisXaa: 0.0 ± 0.0
Ile	5.487IleAla: 5.487 ± 0.079	0.597IleCys: 0.597 ± 0.029	4.68IleAsp: 4.68 ± 0.085	5.27IleGlu: 5.27 ± 0.093	3.262IlePhe: 3.262 ± 0.071	4.986IleGly: 4.986 ± 0.083	1.151IleHis: 1.151 ± 0.042	5.797IleIle: 5.797 ± 0.117	5.466IleLys: 5.466 ± 0.099	6.979IleLeu: 6.979 ± 0.106	1.235IleMet: 1.235 ± 0.036	4.735IleAsn: 4.735 ± 0.08	3.12IlePro: 3.12 ± 0.057	2.409IleGln: 2.409 ± 0.049	2.302IleArg: 2.302 ± 0.057	5.722IleSer: 5.722 ± 0.089	5.194IleThr: 5.194 ± 0.126	4.639IleVal: 4.639 ± 0.084	0.665IleTrp: 0.665 ± 0.03	2.601IleTyr: 2.601 ± 0.064	0.0IleXaa: 0.0 ± 0.0
Lys	5.047LysAla: 5.047 ± 0.105	0.294LysCys: 0.294 ± 0.017	5.03LysAsp: 5.03 ± 0.103	5.754LysGlu: 5.754 ± 0.106	2.84LysPhe: 2.84 ± 0.077	4.19LysGly: 4.19 ± 0.093	1.526LysHis: 1.526 ± 0.052	4.965LysIle: 4.965 ± 0.098	5.586LysLys: 5.586 ± 0.128	6.564LysLeu: 6.564 ± 0.123	1.736LysMet: 1.736 ± 0.06	4.405LysAsn: 4.405 ± 0.079	2.423LysPro: 2.423 ± 0.06	2.936LysGln: 2.936 ± 0.061	2.979LysArg: 2.979 ± 0.08	4.367LysSer: 4.367 ± 0.092	4.869LysThr: 4.869 ± 0.082	4.405LysVal: 4.405 ± 0.093	0.611LysTrp: 0.611 ± 0.03	2.625LysTyr: 2.625 ± 0.058	0.0LysXaa: 0.0 ± 0.0
Leu	5.773LeuAla: 5.773 ± 0.089	0.644LeuCys: 0.644 ± 0.032	5.364LeuAsp: 5.364 ± 0.086	6.245LeuGlu: 6.245 ± 0.102	4.491LeuPhe: 4.491 ± 0.088	5.974LeuGly: 5.974 ± 0.087	1.522LeuHis: 1.522 ± 0.051	6.717LeuIle: 6.717 ± 0.119	7.85LeuLys: 7.85 ± 0.123	8.519LeuLeu: 8.519 ± 0.148	1.966LeuMet: 1.966 ± 0.051	6.102LeuAsn: 6.102 ± 0.085	3.446LeuPro: 3.446 ± 0.065	3.422LeuGln: 3.422 ± 0.063	3.323LeuArg: 3.323 ± 0.072	6.687LeuSer: 6.687 ± 0.099	5.465LeuThr: 5.465 ± 0.115	5.563LeuVal: 5.563 ± 0.098	0.769LeuTrp: 0.769 ± 0.03	3.004LeuTyr: 3.004 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	1.655MetAla: 1.655 ± 0.05	0.136MetCys: 0.136 ± 0.013	1.002MetAsp: 1.002 ± 0.039	1.121MetGlu: 1.121 ± 0.039	0.819MetPhe: 0.819 ± 0.029	1.231MetGly: 1.231 ± 0.039	0.368MetHis: 0.368 ± 0.021	1.344MetIle: 1.344 ± 0.041	1.924MetLys: 1.924 ± 0.049	1.952MetLeu: 1.952 ± 0.055	0.523MetMet: 0.523 ± 0.027	1.207MetAsn: 1.207 ± 0.037	0.855MetPro: 0.855 ± 0.035	0.785MetGln: 0.785 ± 0.031	0.872MetArg: 0.872 ± 0.032	1.493MetSer: 1.493 ± 0.042	1.335MetThr: 1.335 ± 0.039	1.313MetVal: 1.313 ± 0.04	0.142MetTrp: 0.142 ± 0.014	0.709MetTyr: 0.709 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	4.238AsnAla: 4.238 ± 0.086	0.456AsnCys: 0.456 ± 0.03	3.619AsnAsp: 3.619 ± 0.113	3.704AsnGlu: 3.704 ± 0.062	3.084AsnPhe: 3.084 ± 0.062	4.201AsnGly: 4.201 ± 0.151	0.992AsnHis: 0.992 ± 0.034	4.664AsnIle: 4.664 ± 0.075	3.98AsnLys: 3.98 ± 0.088	5.602AsnLeu: 5.602 ± 0.104	1.213AsnMet: 1.213 ± 0.035	4.037AsnAsn: 4.037 ± 0.111	2.749AsnPro: 2.749 ± 0.065	1.99AsnGln: 1.99 ± 0.052	2.101AsnArg: 2.101 ± 0.054	4.057AsnSer: 4.057 ± 0.092	4.386AsnThr: 4.386 ± 0.104	4.003AsnVal: 4.003 ± 0.109	0.722AsnTrp: 0.722 ± 0.029	2.845AsnTyr: 2.845 ± 0.063	0.0AsnXaa: 0.0 ± 0.0
Pro	1.702ProAla: 1.702 ± 0.052	0.211ProCys: 0.211 ± 0.015	2.089ProAsp: 2.089 ± 0.066	2.82ProGlu: 2.82 ± 0.07	1.829ProPhe: 1.829 ± 0.048	1.758ProGly: 1.758 ± 0.062	0.564ProHis: 0.564 ± 0.025	2.716ProIle: 2.716 ± 0.057	2.727ProLys: 2.727 ± 0.078	3.057ProLeu: 3.057 ± 0.057	0.699ProMet: 0.699 ± 0.03	2.337ProAsn: 2.337 ± 0.061	0.725ProPro: 0.725 ± 0.042	1.299ProGln: 1.299 ± 0.04	0.885ProArg: 0.885 ± 0.03	2.143ProSer: 2.143 ± 0.059	2.147ProThr: 2.147 ± 0.075	2.305ProVal: 2.305 ± 0.056	0.289ProTrp: 0.289 ± 0.018	1.343ProTyr: 1.343 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.208GlnAla: 2.208 ± 0.057	0.181GlnCys: 0.181 ± 0.018	2.3GlnAsp: 2.3 ± 0.069	2.406GlnGlu: 2.406 ± 0.058	1.759GlnPhe: 1.759 ± 0.05	1.875GlnGly: 1.875 ± 0.049	0.658GlnHis: 0.658 ± 0.031	2.416GlnIle: 2.416 ± 0.059	2.371GlnLys: 2.371 ± 0.058	3.573GlnLeu: 3.573 ± 0.078	0.81GlnMet: 0.81 ± 0.032	2.109GlnAsn: 2.109 ± 0.056	1.232GlnPro: 1.232 ± 0.038	1.607GlnGln: 1.607 ± 0.05	1.324GlnArg: 1.324 ± 0.038	1.991GlnSer: 1.991 ± 0.042	2.086GlnThr: 2.086 ± 0.066	2.163GlnVal: 2.163 ± 0.053	0.345GlnTrp: 0.345 ± 0.021	1.277GlnTyr: 1.277 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.147ArgAla: 2.147 ± 0.055	0.207ArgCys: 0.207 ± 0.016	1.898ArgAsp: 1.898 ± 0.051	2.184ArgGlu: 2.184 ± 0.054	1.934ArgPhe: 1.934 ± 0.049	1.919ArgGly: 1.919 ± 0.048	0.607ArgHis: 0.607 ± 0.028	2.712ArgIle: 2.712 ± 0.06	2.502ArgLys: 2.502 ± 0.073	3.304ArgLeu: 3.304 ± 0.071	0.831ArgMet: 0.831 ± 0.032	1.881ArgAsn: 1.881 ± 0.047	1.042ArgPro: 1.042 ± 0.035	1.218ArgGln: 1.218 ± 0.042	1.337ArgArg: 1.337 ± 0.043	1.901ArgSer: 1.901 ± 0.054	1.883ArgThr: 1.883 ± 0.05	2.197ArgVal: 2.197 ± 0.06	0.327ArgTrp: 0.327 ± 0.018	1.521ArgTyr: 1.521 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	3.917SerAla: 3.917 ± 0.075	0.661SerCys: 0.661 ± 0.03	3.513SerAsp: 3.513 ± 0.126	4.293SerGlu: 4.293 ± 0.079	3.626SerPhe: 3.626 ± 0.08	4.619SerGly: 4.619 ± 0.102	1.095SerHis: 1.095 ± 0.038	5.218SerIle: 5.218 ± 0.077	4.982SerLys: 4.982 ± 0.094	6.192SerLeu: 6.192 ± 0.103	1.234SerMet: 1.234 ± 0.04	4.019SerAsn: 4.019 ± 0.083	2.087SerPro: 2.087 ± 0.048	2.349SerGln: 2.349 ± 0.057	2.01SerArg: 2.01 ± 0.051	4.255SerSer: 4.255 ± 0.095	3.927SerThr: 3.927 ± 0.083	4.202SerVal: 4.202 ± 0.072	0.649SerTrp: 0.649 ± 0.029	2.802SerTyr: 2.802 ± 0.062	0.0SerXaa: 0.0 ± 0.0
Thr	4.299ThrAla: 4.299 ± 0.129	0.396ThrCys: 0.396 ± 0.023	3.62ThrAsp: 3.62 ± 0.145	3.898ThrGlu: 3.898 ± 0.082	3.237ThrPhe: 3.237 ± 0.061	4.165ThrGly: 4.165 ± 0.138	1.037ThrHis: 1.037 ± 0.032	5.287ThrIle: 5.287 ± 0.089	4.009ThrLys: 4.009 ± 0.077	6.328ThrLeu: 6.328 ± 0.123	1.003ThrMet: 1.003 ± 0.037	3.789ThrAsn: 3.789 ± 0.097	2.663ThrPro: 2.663 ± 0.078	2.154ThrGln: 2.154 ± 0.06	1.72ThrArg: 1.72 ± 0.052	4.233ThrSer: 4.233 ± 0.09	4.716ThrThr: 4.716 ± 0.174	4.578ThrVal: 4.578 ± 0.176	0.595ThrTrp: 0.595 ± 0.037	2.727ThrTyr: 2.727 ± 0.064	0.0ThrXaa: 0.0 ± 0.0
Val	4.295ValAla: 4.295 ± 0.079	0.518ValCys: 0.518 ± 0.027	3.787ValAsp: 3.787 ± 0.13	4.141ValGlu: 4.141 ± 0.068	3.353ValPhe: 3.353 ± 0.07	3.955ValGly: 3.955 ± 0.062	0.967ValHis: 0.967 ± 0.03	5.079ValIle: 5.079 ± 0.098	4.306ValLys: 4.306 ± 0.09	6.063ValLeu: 6.063 ± 0.083	1.387ValMet: 1.387 ± 0.038	4.005ValAsn: 4.005 ± 0.077	2.135ValPro: 2.135 ± 0.052	1.744ValGln: 1.744 ± 0.047	2.001ValArg: 2.001 ± 0.046	4.684ValSer: 4.684 ± 0.077	4.39ValThr: 4.39 ± 0.171	4.49ValVal: 4.49 ± 0.081	0.559ValTrp: 0.559 ± 0.021	2.411ValTyr: 2.411 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.573TrpAla: 0.573 ± 0.026	0.095TrpCys: 0.095 ± 0.01	0.588TrpAsp: 0.588 ± 0.027	0.559TrpGlu: 0.559 ± 0.027	0.57TrpPhe: 0.57 ± 0.028	0.524TrpGly: 0.524 ± 0.023	0.186TrpHis: 0.186 ± 0.015	0.621TrpIle: 0.621 ± 0.029	0.671TrpLys: 0.671 ± 0.034	0.97TrpLeu: 0.97 ± 0.033	0.287TrpMet: 0.287 ± 0.017	0.611TrpAsn: 0.611 ± 0.028	0.24TrpPro: 0.24 ± 0.019	0.395TrpGln: 0.395 ± 0.022	0.37TrpArg: 0.37 ± 0.021	0.592TrpSer: 0.592 ± 0.027	0.527TrpThr: 0.527 ± 0.031	0.591TrpVal: 0.591 ± 0.026	0.144TrpTrp: 0.144 ± 0.014	0.426TrpTyr: 0.426 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.356TyrAla: 2.356 ± 0.061	0.326TyrCys: 0.326 ± 0.02	2.405TyrAsp: 2.405 ± 0.058	2.336TyrGlu: 2.336 ± 0.054	2.235TyrPhe: 2.235 ± 0.058	2.553TyrGly: 2.553 ± 0.058	0.715TyrHis: 0.715 ± 0.028	2.733TyrIle: 2.733 ± 0.061	3.099TyrLys: 3.099 ± 0.072	3.714TyrLeu: 3.714 ± 0.074	0.65TyrMet: 0.65 ± 0.028	2.789TyrAsn: 2.789 ± 0.062	1.347TyrPro: 1.347 ± 0.038	1.298TyrGln: 1.298 ± 0.04	1.526TyrArg: 1.526 ± 0.041	2.541TyrSer: 2.541 ± 0.058	2.581TyrThr: 2.581 ± 0.075	2.197TyrVal: 2.197 ± 0.047	0.421TyrTrp: 0.421 ± 0.023	1.703TyrTyr: 1.703 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2702 proteins (907128 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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