Amino acid dipepetide frequency for Wuhan spider virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.998AlaAla: 2.998 ± 1.605
0.899AlaCys: 0.899 ± 0.693
4.796AlaAsp: 4.796 ± 1.971
4.197AlaGlu: 4.197 ± 0.749
5.096AlaPhe: 5.096 ± 0.557
3.297AlaGly: 3.297 ± 2.412
2.098AlaHis: 2.098 ± 0.646
6.295AlaIle: 6.295 ± 2.417
2.998AlaLys: 2.998 ± 0.616
5.396AlaLeu: 5.396 ± 2.212
1.499AlaMet: 1.499 ± 0.878
3.297AlaAsn: 3.297 ± 1.852
2.098AlaPro: 2.098 ± 2.128
2.098AlaGln: 2.098 ± 1.726
4.197AlaArg: 4.197 ± 1.701
4.496AlaSer: 4.496 ± 1.821
3.597AlaThr: 3.597 ± 2.044
3.297AlaVal: 3.297 ± 0.908
0.0AlaTrp: 0.0 ± 0.0
3.297AlaTyr: 3.297 ± 0.884
0.0AlaXaa: 0.0 ± 0.0
Cys
1.199CysAla: 1.199 ± 0.978
0.0CysCys: 0.0 ± 0.0
0.6CysAsp: 0.6 ± 0.308
0.6CysGlu: 0.6 ± 0.308
1.199CysPhe: 1.199 ± 0.349
0.899CysGly: 0.899 ± 0.462
0.3CysHis: 0.3 ± 0.444
1.499CysIle: 1.499 ± 0.438
0.899CysLys: 0.899 ± 0.462
0.6CysLeu: 0.6 ± 0.308
0.6CysMet: 0.6 ± 0.308
2.098CysAsn: 2.098 ± 1.079
0.6CysPro: 0.6 ± 0.308
1.499CysGln: 1.499 ± 0.463
0.3CysArg: 0.3 ± 0.154
1.499CysSer: 1.499 ± 0.65
1.199CysThr: 1.199 ± 0.617
1.199CysVal: 1.199 ± 0.349
0.6CysTrp: 0.6 ± 0.631
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.297AspAla: 3.297 ± 3.199
1.199AspCys: 1.199 ± 0.617
4.197AspAsp: 4.197 ± 0.742
2.698AspGlu: 2.698 ± 1.158
4.796AspPhe: 4.796 ± 1.925
4.496AspGly: 4.496 ± 0.731
1.499AspHis: 1.499 ± 0.438
4.197AspIle: 4.197 ± 0.749
2.398AspLys: 2.398 ± 1.233
4.197AspLeu: 4.197 ± 1.048
1.499AspMet: 1.499 ± 0.814
2.698AspAsn: 2.698 ± 0.973
3.597AspPro: 3.597 ± 0.613
2.398AspGln: 2.398 ± 0.478
2.098AspArg: 2.098 ± 1.259
3.297AspSer: 3.297 ± 0.952
1.499AspThr: 1.499 ± 0.878
3.597AspVal: 3.597 ± 0.51
1.199AspTrp: 1.199 ± 0.617
1.499AspTyr: 1.499 ± 0.822
0.0AspXaa: 0.0 ± 0.0
Glu
3.597GluAla: 3.597 ± 0.932
1.199GluCys: 1.199 ± 0.705
5.396GluAsp: 5.396 ± 1.971
2.698GluGlu: 2.698 ± 1.387
3.897GluPhe: 3.897 ± 0.745
2.698GluGly: 2.698 ± 0.406
0.6GluHis: 0.6 ± 0.308
2.698GluIle: 2.698 ± 0.406
3.597GluLys: 3.597 ± 1.112
5.096GluLeu: 5.096 ± 1.467
1.499GluMet: 1.499 ± 0.599
2.398GluAsn: 2.398 ± 0.864
1.199GluPro: 1.199 ± 0.617
2.098GluGln: 2.098 ± 1.079
2.098GluArg: 2.098 ± 0.371
3.597GluSer: 3.597 ± 0.78
3.297GluThr: 3.297 ± 0.989
3.597GluVal: 3.597 ± 0.78
0.899GluTrp: 0.899 ± 0.693
1.799GluTyr: 1.799 ± 0.556
0.0GluXaa: 0.0 ± 0.0
Phe
1.799PheAla: 1.799 ± 0.705
0.6PheCys: 0.6 ± 0.352
4.197PheAsp: 4.197 ± 1.401
2.398PheGlu: 2.398 ± 0.959
3.597PhePhe: 3.597 ± 1.41
4.197PheGly: 4.197 ± 2.227
0.6PheHis: 0.6 ± 0.887
3.597PheIle: 3.597 ± 1.061
4.197PheLys: 4.197 ± 1.292
3.897PheLeu: 3.897 ± 1.242
0.6PheMet: 0.6 ± 0.308
2.698PheAsn: 2.698 ± 0.879
2.998PhePro: 2.998 ± 2.406
2.998PheGln: 2.998 ± 1.198
1.799PheArg: 1.799 ± 0.63
6.894PheSer: 6.894 ± 1.74
2.998PheThr: 2.998 ± 0.91
3.297PheVal: 3.297 ± 1.555
1.499PheTrp: 1.499 ± 0.822
1.499PheTyr: 1.499 ± 0.771
0.0PheXaa: 0.0 ± 0.0
Gly
4.197GlyAla: 4.197 ± 0.922
1.199GlyCys: 1.199 ± 0.349
2.098GlyAsp: 2.098 ± 0.371
3.597GlyGlu: 3.597 ± 1.112
2.998GlyPhe: 2.998 ± 0.925
2.398GlyGly: 2.398 ± 0.478
0.3GlyHis: 0.3 ± 0.444
4.197GlyIle: 4.197 ± 0.749
4.796GlyLys: 4.796 ± 1.424
5.396GlyLeu: 5.396 ± 3.218
0.6GlyMet: 0.6 ± 0.308
2.998GlyAsn: 2.998 ± 1.891
1.799GlyPro: 1.799 ± 1.057
2.098GlyGln: 2.098 ± 1.668
0.899GlyArg: 0.899 ± 0.581
3.897GlySer: 3.897 ± 1.284
2.998GlyThr: 2.998 ± 1.088
2.398GlyVal: 2.398 ± 0.959
0.6GlyTrp: 0.6 ± 0.875
3.297GlyTyr: 3.297 ± 0.425
0.0GlyXaa: 0.0 ± 0.0
His
2.398HisAla: 2.398 ± 1.92
0.6HisCys: 0.6 ± 0.308
1.499HisAsp: 1.499 ± 0.438
0.6HisGlu: 0.6 ± 0.308
1.499HisPhe: 1.499 ± 0.438
0.6HisGly: 0.6 ± 0.631
0.3HisHis: 0.3 ± 0.154
1.799HisIle: 1.799 ± 0.63
1.199HisLys: 1.199 ± 0.569
0.899HisLeu: 0.899 ± 0.462
0.0HisMet: 0.0 ± 0.0
1.199HisAsn: 1.199 ± 0.349
1.499HisPro: 1.499 ± 0.463
1.199HisGln: 1.199 ± 0.705
0.6HisArg: 0.6 ± 0.308
0.899HisSer: 0.899 ± 0.462
1.499HisThr: 1.499 ± 0.599
0.899HisVal: 0.899 ± 0.462
0.899HisTrp: 0.899 ± 0.462
0.6HisTyr: 0.6 ± 0.352
0.0HisXaa: 0.0 ± 0.0
Ile
4.796IleAla: 4.796 ± 0.955
0.6IleCys: 0.6 ± 0.308
6.595IleAsp: 6.595 ± 1.264
3.897IleGlu: 3.897 ± 0.622
2.998IlePhe: 2.998 ± 0.743
4.796IleGly: 4.796 ± 0.77
2.698IleHis: 2.698 ± 0.406
5.695IleIle: 5.695 ± 2.482
7.194IleLys: 7.194 ± 1.819
4.796IleLeu: 4.796 ± 1.085
3.897IleMet: 3.897 ± 1.481
5.096IleAsn: 5.096 ± 1.743
4.796IlePro: 4.796 ± 1.394
3.597IleGln: 3.597 ± 0.51
1.499IleArg: 1.499 ± 0.438
5.695IleSer: 5.695 ± 1.113
3.597IleThr: 3.597 ± 1.584
3.297IleVal: 3.297 ± 0.908
1.199IleTrp: 1.199 ± 0.569
2.998IleTyr: 2.998 ± 0.875
0.0IleXaa: 0.0 ± 0.0
Lys
3.597LysAla: 3.597 ± 0.683
1.499LysCys: 1.499 ± 0.771
2.998LysAsp: 2.998 ± 0.616
5.096LysGlu: 5.096 ± 1.801
3.597LysPhe: 3.597 ± 0.936
3.897LysGly: 3.897 ± 0.599
0.899LysHis: 0.899 ± 0.693
5.695LysIle: 5.695 ± 1.916
4.796LysLys: 4.796 ± 2.467
4.496LysLeu: 4.496 ± 1.316
1.499LysMet: 1.499 ± 0.438
5.396LysAsn: 5.396 ± 0.993
3.297LysPro: 3.297 ± 1.271
2.698LysGln: 2.698 ± 1.721
2.398LysArg: 2.398 ± 1.781
5.096LysSer: 5.096 ± 1.435
3.297LysThr: 3.297 ± 1.271
5.396LysVal: 5.396 ± 1.552
0.899LysTrp: 0.899 ± 0.462
2.698LysTyr: 2.698 ± 0.986
0.0LysXaa: 0.0 ± 0.0
Leu
5.995LeuAla: 5.995 ± 1.711
1.499LeuCys: 1.499 ± 0.771
3.597LeuAsp: 3.597 ± 0.882
5.396LeuGlu: 5.396 ± 1.331
4.197LeuPhe: 4.197 ± 1.048
4.197LeuGly: 4.197 ± 1.586
1.499LeuHis: 1.499 ± 0.438
6.894LeuIle: 6.894 ± 1.089
4.796LeuLys: 4.796 ± 0.951
8.094LeuLeu: 8.094 ± 1.357
2.398LeuMet: 2.398 ± 0.823
5.695LeuAsn: 5.695 ± 2.263
5.396LeuPro: 5.396 ± 2.395
4.796LeuGln: 4.796 ± 2.781
3.597LeuArg: 3.597 ± 2.044
2.098LeuSer: 2.098 ± 1.075
2.998LeuThr: 2.998 ± 0.386
2.998LeuVal: 2.998 ± 0.875
0.0LeuTrp: 0.0 ± 0.0
2.998LeuTyr: 2.998 ± 0.955
0.0LeuXaa: 0.0 ± 0.0
Met
2.398MetAla: 2.398 ± 2.247
0.899MetCys: 0.899 ± 0.693
1.799MetAsp: 1.799 ± 0.793
0.899MetGlu: 0.899 ± 0.462
0.6MetPhe: 0.6 ± 0.308
1.199MetGly: 1.199 ± 0.569
0.3MetHis: 0.3 ± 0.154
1.799MetIle: 1.799 ± 0.925
2.098MetLys: 2.098 ± 1.007
1.499MetLeu: 1.499 ± 1.203
0.3MetMet: 0.3 ± 0.154
1.499MetAsn: 1.499 ± 0.771
0.899MetPro: 0.899 ± 0.315
0.6MetGln: 0.6 ± 0.308
1.799MetArg: 1.799 ± 1.893
2.698MetSer: 2.698 ± 0.879
0.899MetThr: 0.899 ± 0.462
1.799MetVal: 1.799 ± 0.556
0.899MetTrp: 0.899 ± 0.462
1.199MetTyr: 1.199 ± 0.705
0.0MetXaa: 0.0 ± 0.0
Asn
3.597AsnAla: 3.597 ± 1.728
0.6AsnCys: 0.6 ± 0.631
1.199AsnAsp: 1.199 ± 2.168
3.897AsnGlu: 3.897 ± 0.622
2.098AsnPhe: 2.098 ± 1.691
2.998AsnGly: 2.998 ± 0.875
1.499AsnHis: 1.499 ± 0.463
5.995AsnIle: 5.995 ± 0.495
3.297AsnLys: 3.297 ± 1.052
5.695AsnLeu: 5.695 ± 1.679
2.398AsnMet: 2.398 ± 0.413
3.297AsnAsn: 3.297 ± 1.8
3.297AsnPro: 3.297 ± 1.25
2.998AsnGln: 2.998 ± 0.616
2.098AsnArg: 2.098 ± 0.805
6.894AsnSer: 6.894 ± 1.462
2.998AsnThr: 2.998 ± 1.089
3.897AsnVal: 3.897 ± 0.982
0.3AsnTrp: 0.3 ± 0.154
3.297AsnTyr: 3.297 ± 4.676
0.0AsnXaa: 0.0 ± 0.0
Pro
3.597ProAla: 3.597 ± 1.046
0.899ProCys: 0.899 ± 0.315
1.499ProAsp: 1.499 ± 0.599
4.197ProGlu: 4.197 ± 0.742
3.897ProPhe: 3.897 ± 1.711
3.897ProGly: 3.897 ± 1.253
0.3ProHis: 0.3 ± 0.154
3.897ProIle: 3.897 ± 0.599
3.597ProLys: 3.597 ± 1.046
3.897ProLeu: 3.897 ± 1.266
0.6ProMet: 0.6 ± 0.485
3.297ProAsn: 3.297 ± 0.989
1.499ProPro: 1.499 ± 1.135
2.098ProGln: 2.098 ± 0.688
1.499ProArg: 1.499 ± 0.438
3.597ProSer: 3.597 ± 0.823
1.799ProThr: 1.799 ± 0.91
3.297ProVal: 3.297 ± 0.664
0.3ProTrp: 0.3 ± 0.154
1.499ProTyr: 1.499 ± 1.528
0.0ProXaa: 0.0 ± 0.0
Gln
4.197GlnAla: 4.197 ± 2.333
0.3GlnCys: 0.3 ± 0.154
1.799GlnAsp: 1.799 ± 1.533
2.398GlnGlu: 2.398 ± 0.864
2.098GlnPhe: 2.098 ± 1.079
1.199GlnGly: 1.199 ± 1.152
0.3GlnHis: 0.3 ± 0.154
1.799GlnIle: 1.799 ± 0.705
4.496GlnLys: 4.496 ± 1.759
2.398GlnLeu: 2.398 ± 0.829
1.199GlnMet: 1.199 ± 0.569
2.698GlnAsn: 2.698 ± 3.776
3.297GlnPro: 3.297 ± 0.842
1.199GlnGln: 1.199 ± 0.349
2.098GlnArg: 2.098 ± 0.793
3.897GlnSer: 3.897 ± 0.467
1.799GlnThr: 1.799 ± 0.664
2.398GlnVal: 2.398 ± 0.829
0.6GlnTrp: 0.6 ± 0.887
1.799GlnTyr: 1.799 ± 0.556
0.0GlnXaa: 0.0 ± 0.0
Arg
3.597ArgAla: 3.597 ± 2.88
0.6ArgCys: 0.6 ± 0.308
2.098ArgAsp: 2.098 ± 1.061
1.499ArgGlu: 1.499 ± 0.463
0.899ArgPhe: 0.899 ± 1.479
0.899ArgGly: 0.899 ± 0.786
0.3ArgHis: 0.3 ± 0.154
3.897ArgIle: 3.897 ± 1.242
1.799ArgLys: 1.799 ± 1.387
3.297ArgLeu: 3.297 ± 0.745
0.899ArgMet: 0.899 ± 1.336
2.998ArgAsn: 2.998 ± 0.925
1.499ArgPro: 1.499 ± 0.599
1.199ArgGln: 1.199 ± 0.349
1.799ArgArg: 1.799 ± 0.664
1.499ArgSer: 1.499 ± 0.944
2.098ArgThr: 2.098 ± 1.485
3.297ArgVal: 3.297 ± 0.908
0.0ArgTrp: 0.0 ± 0.0
1.799ArgTyr: 1.799 ± 0.63
0.0ArgXaa: 0.0 ± 0.0
Ser
5.096SerAla: 5.096 ± 2.14
1.499SerCys: 1.499 ± 0.771
3.297SerAsp: 3.297 ± 1.155
2.998SerGlu: 2.998 ± 0.91
3.597SerPhe: 3.597 ± 1.112
3.897SerGly: 3.897 ± 1.578
1.199SerHis: 1.199 ± 0.569
6.894SerIle: 6.894 ± 1.626
5.096SerLys: 5.096 ± 1.208
5.096SerLeu: 5.096 ± 0.557
1.499SerMet: 1.499 ± 0.889
6.295SerAsn: 6.295 ± 2.873
3.297SerPro: 3.297 ± 0.908
1.499SerGln: 1.499 ± 1.101
3.297SerArg: 3.297 ± 0.745
5.995SerSer: 5.995 ± 1.415
4.197SerThr: 4.197 ± 1.815
5.396SerVal: 5.396 ± 1.634
0.6SerTrp: 0.6 ± 0.308
2.098SerTyr: 2.098 ± 0.88
0.0SerXaa: 0.0 ± 0.0
Thr
2.998ThrAla: 2.998 ± 0.386
0.899ThrCys: 0.899 ± 0.462
1.199ThrAsp: 1.199 ± 0.569
3.597ThrGlu: 3.597 ± 0.51
2.698ThrPhe: 2.698 ± 0.406
2.998ThrGly: 2.998 ± 1.998
1.499ThrHis: 1.499 ± 0.438
6.295ThrIle: 6.295 ± 1.885
3.597ThrLys: 3.597 ± 0.882
3.897ThrLeu: 3.897 ± 2.823
1.199ThrMet: 1.199 ± 0.569
0.899ThrAsn: 0.899 ± 1.121
3.597ThrPro: 3.597 ± 1.16
1.799ThrGln: 1.799 ± 0.793
1.199ThrArg: 1.199 ± 0.569
2.998ThrSer: 2.998 ± 0.955
1.799ThrThr: 1.799 ± 1.778
2.098ThrVal: 2.098 ± 0.997
0.6ThrTrp: 0.6 ± 0.352
2.998ThrTyr: 2.998 ± 0.688
0.0ThrXaa: 0.0 ± 0.0
Val
2.398ValAla: 2.398 ± 0.697
1.199ValCys: 1.199 ± 0.349
3.897ValAsp: 3.897 ± 2.369
2.098ValGlu: 2.098 ± 0.371
2.698ValPhe: 2.698 ± 0.776
1.499ValGly: 1.499 ± 0.65
2.698ValHis: 2.698 ± 1.387
3.897ValIle: 3.897 ± 1.266
5.396ValLys: 5.396 ± 1.668
4.796ValLeu: 4.796 ± 1.301
2.098ValMet: 2.098 ± 0.997
4.496ValAsn: 4.496 ± 0.683
2.698ValPro: 2.698 ± 0.776
2.998ValGln: 2.998 ± 0.91
1.799ValArg: 1.799 ± 0.39
4.197ValSer: 4.197 ± 0.749
2.698ValThr: 2.698 ± 0.776
2.998ValVal: 2.998 ± 1.12
0.3ValTrp: 0.3 ± 0.444
3.297ValTyr: 3.297 ± 0.425
0.0ValXaa: 0.0 ± 0.0
Trp
1.799TrpAla: 1.799 ± 0.705
0.3TrpCys: 0.3 ± 0.154
0.899TrpAsp: 0.899 ± 0.786
0.0TrpGlu: 0.0 ± 0.0
0.899TrpPhe: 0.899 ± 0.462
0.6TrpGly: 0.6 ± 0.875
0.6TrpHis: 0.6 ± 0.308
0.6TrpIle: 0.6 ± 0.308
0.3TrpLys: 0.3 ± 0.154
1.499TrpLeu: 1.499 ± 1.203
0.3TrpMet: 0.3 ± 0.444
0.899TrpAsn: 0.899 ± 0.849
0.6TrpPro: 0.6 ± 0.308
0.6TrpGln: 0.6 ± 0.308
0.3TrpArg: 0.3 ± 0.154
0.6TrpSer: 0.6 ± 0.308
0.6TrpThr: 0.6 ± 0.352
0.6TrpVal: 0.6 ± 0.308
0.3TrpTrp: 0.3 ± 0.154
0.3TrpTyr: 0.3 ± 0.712
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.398TyrAla: 2.398 ± 0.823
0.899TyrCys: 0.899 ± 0.315
2.698TyrAsp: 2.698 ± 0.986
1.199TyrGlu: 1.199 ± 0.617
2.998TyrPhe: 2.998 ± 0.743
2.098TyrGly: 2.098 ± 1.079
1.199TyrHis: 1.199 ± 0.349
2.098TyrIle: 2.098 ± 0.371
2.698TyrLys: 2.698 ± 0.501
4.197TyrLeu: 4.197 ± 3.312
1.199TyrMet: 1.199 ± 0.67
2.398TyrAsn: 2.398 ± 0.885
1.199TyrPro: 1.199 ± 0.569
1.499TyrGln: 1.499 ± 2.286
0.6TyrArg: 0.6 ± 0.887
3.297TyrSer: 3.297 ± 1.431
2.998TyrThr: 2.998 ± 0.875
2.398TyrVal: 2.398 ± 0.959
0.899TyrTrp: 0.899 ± 0.581
1.499TyrTyr: 1.499 ± 1.203
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3337 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski