Amino acid dipepetide frequency for Glossina hytrovirus (isolate Glossina pallidipes/Ethiopia/Seibersdorf/-) (GHV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.134AlaAla: 1.134 ± 0.143
0.402AlaCys: 0.402 ± 0.087
1.427AlaAsp: 1.427 ± 0.163
1.738AlaGlu: 1.738 ± 0.254
1.153AlaPhe: 1.153 ± 0.182
0.951AlaGly: 0.951 ± 0.154
0.622AlaHis: 0.622 ± 0.116
2.872AlaIle: 2.872 ± 0.241
1.994AlaLys: 1.994 ± 0.195
2.762AlaLeu: 2.762 ± 0.23
0.567AlaMet: 0.567 ± 0.091
2.25AlaAsn: 2.25 ± 0.203
0.787AlaPro: 0.787 ± 0.142
1.171AlaGln: 1.171 ± 0.176
1.153AlaArg: 1.153 ± 0.144
1.701AlaSer: 1.701 ± 0.163
1.738AlaThr: 1.738 ± 0.161
1.5AlaVal: 1.5 ± 0.17
0.183AlaTrp: 0.183 ± 0.058
1.171AlaTyr: 1.171 ± 0.156
0.0AlaXaa: 0.0 ± 0.0
Cys
0.494CysAla: 0.494 ± 0.106
0.366CysCys: 0.366 ± 0.093
1.079CysAsp: 1.079 ± 0.183
0.933CysGlu: 0.933 ± 0.175
1.061CysPhe: 1.061 ± 0.153
0.64CysGly: 0.64 ± 0.122
0.293CysHis: 0.293 ± 0.095
2.122CysIle: 2.122 ± 0.266
1.592CysLys: 1.592 ± 0.255
1.537CysLeu: 1.537 ± 0.17
0.494CysMet: 0.494 ± 0.089
1.628CysAsn: 1.628 ± 0.19
0.823CysPro: 0.823 ± 0.137
0.64CysGln: 0.64 ± 0.14
0.713CysArg: 0.713 ± 0.132
1.39CysSer: 1.39 ± 0.222
1.098CysThr: 1.098 ± 0.18
1.006CysVal: 1.006 ± 0.154
0.037CysTrp: 0.037 ± 0.024
0.842CysTyr: 0.842 ± 0.149
0.0CysXaa: 0.0 ± 0.0
Asp
1.592AspAla: 1.592 ± 0.147
0.896AspCys: 0.896 ± 0.153
4.921AspAsp: 4.921 ± 0.507
5.177AspGlu: 5.177 ± 0.669
3.348AspPhe: 3.348 ± 0.327
1.683AspGly: 1.683 ± 0.215
0.695AspHis: 0.695 ± 0.102
5.616AspIle: 5.616 ± 0.286
4.372AspLys: 4.372 ± 0.325
4.519AspLeu: 4.519 ± 0.3
1.226AspMet: 1.226 ± 0.151
5.324AspAsn: 5.324 ± 0.311
1.299AspPro: 1.299 ± 0.166
1.482AspGln: 1.482 ± 0.316
2.031AspArg: 2.031 ± 0.35
3.256AspSer: 3.256 ± 0.306
2.47AspThr: 2.47 ± 0.248
3.183AspVal: 3.183 ± 0.241
0.457AspTrp: 0.457 ± 0.098
2.488AspTyr: 2.488 ± 0.227
0.0AspXaa: 0.0 ± 0.0
Glu
1.5GluAla: 1.5 ± 0.291
0.823GluCys: 0.823 ± 0.155
3.293GluAsp: 3.293 ± 0.319
6.421GluGlu: 6.421 ± 1.903
3.165GluPhe: 3.165 ± 0.2
1.189GluGly: 1.189 ± 0.16
1.189GluHis: 1.189 ± 0.15
5.342GluIle: 5.342 ± 0.625
6.513GluLys: 6.513 ± 0.951
6.257GluLeu: 6.257 ± 0.652
1.427GluMet: 1.427 ± 0.201
5.525GluAsn: 5.525 ± 0.312
2.031GluPro: 2.031 ± 0.268
3.714GluGln: 3.714 ± 1.222
2.451GluArg: 2.451 ± 0.294
3.677GluSer: 3.677 ± 0.675
2.982GluThr: 2.982 ± 0.248
2.14GluVal: 2.14 ± 0.278
0.421GluTrp: 0.421 ± 0.089
3.366GluTyr: 3.366 ± 0.281
0.0GluXaa: 0.0 ± 0.0
Phe
1.39PheAla: 1.39 ± 0.186
1.226PheCys: 1.226 ± 0.161
3.22PheAsp: 3.22 ± 0.281
2.781PheGlu: 2.781 ± 0.245
3.403PhePhe: 3.403 ± 0.328
1.445PheGly: 1.445 ± 0.191
1.171PheHis: 1.171 ± 0.16
5.909PheIle: 5.909 ± 0.58
5.324PheLys: 5.324 ± 0.321
5.635PheLeu: 5.635 ± 0.397
0.622PheMet: 0.622 ± 0.1
5.854PheAsn: 5.854 ± 0.504
1.665PhePro: 1.665 ± 0.206
1.592PheGln: 1.592 ± 0.222
1.5PheArg: 1.5 ± 0.258
3.952PheSer: 3.952 ± 0.36
2.598PheThr: 2.598 ± 0.301
2.323PheVal: 2.323 ± 0.218
0.165PheTrp: 0.165 ± 0.05
3.037PheTyr: 3.037 ± 0.322
0.0PheXaa: 0.0 ± 0.0
Gly
0.531GlyAla: 0.531 ± 0.1
0.402GlyCys: 0.402 ± 0.102
1.628GlyAsp: 1.628 ± 0.184
1.848GlyGlu: 1.848 ± 0.173
1.573GlyPhe: 1.573 ± 0.166
1.079GlyGly: 1.079 ± 0.188
1.409GlyHis: 1.409 ± 0.397
2.708GlyIle: 2.708 ± 0.253
2.049GlyLys: 2.049 ± 0.188
1.903GlyLeu: 1.903 ± 0.152
0.329GlyMet: 0.329 ± 0.077
2.031GlyAsn: 2.031 ± 0.239
0.713GlyPro: 0.713 ± 0.132
0.805GlyGln: 0.805 ± 0.112
0.896GlyArg: 0.896 ± 0.168
1.683GlySer: 1.683 ± 0.204
1.445GlyThr: 1.445 ± 0.177
0.988GlyVal: 0.988 ± 0.156
0.165GlyTrp: 0.165 ± 0.056
1.134GlyTyr: 1.134 ± 0.171
0.0GlyXaa: 0.0 ± 0.0
His
0.787HisAla: 0.787 ± 0.132
0.311HisCys: 0.311 ± 0.087
1.153HisAsp: 1.153 ± 0.167
0.896HisGlu: 0.896 ± 0.141
1.793HisPhe: 1.793 ± 0.257
0.604HisGly: 0.604 ± 0.114
0.384HisHis: 0.384 ± 0.087
2.36HisIle: 2.36 ± 0.223
1.5HisLys: 1.5 ± 0.159
2.506HisLeu: 2.506 ± 0.258
0.421HisMet: 0.421 ± 0.102
1.281HisAsn: 1.281 ± 0.144
0.549HisPro: 0.549 ± 0.11
0.951HisGln: 0.951 ± 0.145
0.768HisArg: 0.768 ± 0.109
1.207HisSer: 1.207 ± 0.154
0.896HisThr: 0.896 ± 0.135
1.518HisVal: 1.518 ± 0.211
0.238HisTrp: 0.238 ± 0.068
1.336HisTyr: 1.336 ± 0.233
0.0HisXaa: 0.0 ± 0.0
Ile
3.073IleAla: 3.073 ± 0.272
1.848IleCys: 1.848 ± 0.244
6.037IleAsp: 6.037 ± 0.314
6.257IleGlu: 6.257 ± 0.556
5.287IlePhe: 5.287 ± 0.466
2.14IleGly: 2.14 ± 0.175
2.214IleHis: 2.214 ± 0.266
11.288IleIle: 11.288 ± 0.668
8.653IleLys: 8.653 ± 0.458
9.312IleLeu: 9.312 ± 0.431
2.616IleMet: 2.616 ± 0.276
11.233IleAsn: 11.233 ± 0.544
3.11IlePro: 3.11 ± 0.343
3.33IleGln: 3.33 ± 0.284
2.945IleArg: 2.945 ± 0.229
6.604IleSer: 6.604 ± 0.343
6.165IleThr: 6.165 ± 0.356
4.72IleVal: 4.72 ± 0.267
0.75IleTrp: 0.75 ± 0.107
5.488IleTyr: 5.488 ± 0.491
0.0IleXaa: 0.0 ± 0.0
Lys
1.829LysAla: 1.829 ± 0.2
2.14LysCys: 2.14 ± 0.339
4.098LysAsp: 4.098 ± 0.454
5.287LysGlu: 5.287 ± 0.784
4.537LysPhe: 4.537 ± 0.392
1.336LysGly: 1.336 ± 0.161
2.159LysHis: 2.159 ± 0.171
8.233LysIle: 8.233 ± 0.447
9.897LysLys: 9.897 ± 0.961
8.489LysLeu: 8.489 ± 0.42
2.36LysMet: 2.36 ± 0.218
8.397LysAsn: 8.397 ± 0.435
2.287LysPro: 2.287 ± 0.218
3.952LysGln: 3.952 ± 0.422
3.604LysArg: 3.604 ± 0.573
4.683LysSer: 4.683 ± 0.371
4.592LysThr: 4.592 ± 0.376
3.0LysVal: 3.0 ± 0.185
0.713LysTrp: 0.713 ± 0.109
5.763LysTyr: 5.763 ± 0.419
0.0LysXaa: 0.0 ± 0.0
Leu
2.762LeuAla: 2.762 ± 0.263
1.683LeuCys: 1.683 ± 0.229
5.031LeuAsp: 5.031 ± 0.356
5.36LeuGlu: 5.36 ± 0.674
5.379LeuPhe: 5.379 ± 0.382
2.031LeuGly: 2.031 ± 0.243
1.921LeuHis: 1.921 ± 0.176
8.727LeuIle: 8.727 ± 0.401
9.038LeuLys: 9.038 ± 0.484
9.806LeuLeu: 9.806 ± 0.561
2.122LeuMet: 2.122 ± 0.172
9.769LeuAsn: 9.769 ± 0.513
3.311LeuPro: 3.311 ± 0.344
4.244LeuGln: 4.244 ± 0.324
3.165LeuArg: 3.165 ± 0.224
6.129LeuSer: 6.129 ± 0.395
5.287LeuThr: 5.287 ± 0.295
3.769LeuVal: 3.769 ± 0.256
0.457LeuTrp: 0.457 ± 0.091
5.049LeuTyr: 5.049 ± 0.426
0.0LeuXaa: 0.0 ± 0.0
Met
1.207MetAla: 1.207 ± 0.122
0.512MetCys: 0.512 ± 0.108
1.226MetAsp: 1.226 ± 0.154
1.409MetGlu: 1.409 ± 0.196
1.079MetPhe: 1.079 ± 0.154
0.75MetGly: 0.75 ± 0.102
0.494MetHis: 0.494 ± 0.101
1.592MetIle: 1.592 ± 0.182
1.994MetLys: 1.994 ± 0.168
2.269MetLeu: 2.269 ± 0.175
0.439MetMet: 0.439 ± 0.1
2.653MetAsn: 2.653 ± 0.377
1.354MetPro: 1.354 ± 0.185
0.878MetGln: 0.878 ± 0.123
1.024MetArg: 1.024 ± 0.134
1.647MetSer: 1.647 ± 0.178
1.226MetThr: 1.226 ± 0.133
0.933MetVal: 0.933 ± 0.112
0.165MetTrp: 0.165 ± 0.057
1.024MetTyr: 1.024 ± 0.142
0.0MetXaa: 0.0 ± 0.0
Asn
2.488AsnAla: 2.488 ± 0.217
1.683AsnCys: 1.683 ± 0.236
5.69AsnAsp: 5.69 ± 0.41
5.836AsnGlu: 5.836 ± 0.413
5.36AsnPhe: 5.36 ± 0.439
2.58AsnGly: 2.58 ± 0.237
1.555AsnHis: 1.555 ± 0.2
11.818AsnIle: 11.818 ± 0.497
8.233AsnLys: 8.233 ± 0.455
8.214AsnLeu: 8.214 ± 0.386
2.909AsnMet: 2.909 ± 0.394
9.989AsnAsn: 9.989 ± 0.72
1.939AsnPro: 1.939 ± 0.231
2.287AsnGln: 2.287 ± 0.208
2.927AsnArg: 2.927 ± 0.193
6.092AsnSer: 6.092 ± 0.344
4.72AsnThr: 4.72 ± 0.42
4.976AsnVal: 4.976 ± 0.371
1.043AsnTrp: 1.043 ± 0.178
4.757AsnTyr: 4.757 ± 0.332
0.0AsnXaa: 0.0 ± 0.0
Pro
0.713ProAla: 0.713 ± 0.117
0.421ProCys: 0.421 ± 0.094
1.518ProAsp: 1.518 ± 0.206
1.518ProGlu: 1.518 ± 0.221
1.445ProPhe: 1.445 ± 0.176
1.244ProGly: 1.244 ± 0.261
0.787ProHis: 0.787 ± 0.129
3.805ProIle: 3.805 ± 0.331
1.829ProLys: 1.829 ± 0.205
3.073ProLeu: 3.073 ± 0.283
0.549ProMet: 0.549 ± 0.116
2.634ProAsn: 2.634 ± 0.291
1.884ProPro: 1.884 ± 0.255
1.5ProGln: 1.5 ± 0.161
1.098ProArg: 1.098 ± 0.17
3.0ProSer: 3.0 ± 0.278
1.994ProThr: 1.994 ± 0.233
1.5ProVal: 1.5 ± 0.174
0.165ProTrp: 0.165 ± 0.061
1.537ProTyr: 1.537 ± 0.178
0.0ProXaa: 0.0 ± 0.0
Gln
0.805GlnAla: 0.805 ± 0.117
0.75GlnCys: 0.75 ± 0.155
1.445GlnAsp: 1.445 ± 0.249
2.634GlnGlu: 2.634 ± 0.787
1.958GlnPhe: 1.958 ± 0.227
0.585GlnGly: 0.585 ± 0.117
0.988GlnHis: 0.988 ± 0.152
4.409GlnIle: 4.409 ± 0.384
2.36GlnLys: 2.36 ± 0.323
5.068GlnLeu: 5.068 ± 0.435
1.299GlnMet: 1.299 ± 0.132
2.14GlnAsn: 2.14 ± 0.209
1.701GlnPro: 1.701 ± 0.373
3.696GlnGln: 3.696 ± 0.648
1.61GlnArg: 1.61 ± 0.247
2.104GlnSer: 2.104 ± 0.337
1.811GlnThr: 1.811 ± 0.227
1.665GlnVal: 1.665 ± 0.184
0.311GlnTrp: 0.311 ± 0.084
1.903GlnTyr: 1.903 ± 0.196
0.0GlnXaa: 0.0 ± 0.0
Arg
0.768ArgAla: 0.768 ± 0.105
0.713ArgCys: 0.713 ± 0.14
1.756ArgAsp: 1.756 ± 0.217
2.214ArgGlu: 2.214 ± 0.32
1.903ArgPhe: 1.903 ± 0.237
1.079ArgGly: 1.079 ± 0.164
0.988ArgHis: 0.988 ± 0.14
2.872ArgIle: 2.872 ± 0.245
3.586ArgLys: 3.586 ± 0.414
3.0ArgLeu: 3.0 ± 0.249
0.805ArgMet: 0.805 ± 0.117
3.458ArgAsn: 3.458 ± 0.339
0.988ArgPro: 0.988 ± 0.137
1.756ArgGln: 1.756 ± 0.28
1.555ArgArg: 1.555 ± 0.152
1.994ArgSer: 1.994 ± 0.281
1.354ArgThr: 1.354 ± 0.173
1.573ArgVal: 1.573 ± 0.145
0.256ArgTrp: 0.256 ± 0.088
1.775ArgTyr: 1.775 ± 0.208
0.0ArgXaa: 0.0 ± 0.0
Ser
1.701SerAla: 1.701 ± 0.177
1.244SerCys: 1.244 ± 0.194
3.897SerAsp: 3.897 ± 0.387
3.787SerGlu: 3.787 ± 0.464
3.275SerPhe: 3.275 ± 0.343
2.012SerGly: 2.012 ± 0.221
1.317SerHis: 1.317 ± 0.161
7.043SerIle: 7.043 ± 0.359
4.83SerLys: 4.83 ± 0.362
5.873SerLeu: 5.873 ± 0.319
1.5SerMet: 1.5 ± 0.147
5.086SerAsn: 5.086 ± 0.323
2.067SerPro: 2.067 ± 0.207
2.122SerGln: 2.122 ± 0.176
2.195SerArg: 2.195 ± 0.222
5.488SerSer: 5.488 ± 0.412
4.409SerThr: 4.409 ± 0.385
3.384SerVal: 3.384 ± 0.245
0.384SerTrp: 0.384 ± 0.098
2.689SerTyr: 2.689 ± 0.26
0.0SerXaa: 0.0 ± 0.0
Thr
1.683ThrAla: 1.683 ± 0.215
0.823ThrCys: 0.823 ± 0.117
2.854ThrAsp: 2.854 ± 0.24
3.33ThrGlu: 3.33 ± 0.431
3.092ThrPhe: 3.092 ± 0.301
1.354ThrGly: 1.354 ± 0.182
1.134ThrHis: 1.134 ± 0.137
5.598ThrIle: 5.598 ± 0.397
4.299ThrLys: 4.299 ± 0.356
5.031ThrLeu: 5.031 ± 0.303
1.427ThrMet: 1.427 ± 0.188
5.251ThrAsn: 5.251 ± 0.408
1.811ThrPro: 1.811 ± 0.251
1.665ThrGln: 1.665 ± 0.204
1.811ThrArg: 1.811 ± 0.189
3.622ThrSer: 3.622 ± 0.19
4.757ThrThr: 4.757 ± 0.569
2.634ThrVal: 2.634 ± 0.213
0.293ThrTrp: 0.293 ± 0.07
1.939ThrTyr: 1.939 ± 0.227
0.0ThrXaa: 0.0 ± 0.0
Val
1.372ValAla: 1.372 ± 0.154
0.97ValCys: 0.97 ± 0.158
2.671ValAsp: 2.671 ± 0.205
3.055ValGlu: 3.055 ± 0.432
3.147ValPhe: 3.147 ± 0.294
1.226ValGly: 1.226 ± 0.177
0.988ValHis: 0.988 ± 0.129
4.482ValIle: 4.482 ± 0.268
3.75ValLys: 3.75 ± 0.235
3.586ValLeu: 3.586 ± 0.264
1.226ValMet: 1.226 ± 0.143
4.153ValAsn: 4.153 ± 0.315
1.848ValPro: 1.848 ± 0.184
1.738ValGln: 1.738 ± 0.203
1.427ValArg: 1.427 ± 0.178
2.689ValSer: 2.689 ± 0.207
2.122ValThr: 2.122 ± 0.191
2.305ValVal: 2.305 ± 0.283
0.201ValTrp: 0.201 ± 0.063
2.689ValTyr: 2.689 ± 0.279
0.0ValXaa: 0.0 ± 0.0
Trp
0.274TrpAla: 0.274 ± 0.067
0.348TrpCys: 0.348 ± 0.092
0.402TrpAsp: 0.402 ± 0.089
0.329TrpGlu: 0.329 ± 0.08
0.256TrpPhe: 0.256 ± 0.075
0.128TrpGly: 0.128 ± 0.048
0.201TrpHis: 0.201 ± 0.061
0.494TrpIle: 0.494 ± 0.117
0.768TrpLys: 0.768 ± 0.115
0.677TrpLeu: 0.677 ± 0.122
0.146TrpMet: 0.146 ± 0.05
0.366TrpAsn: 0.366 ± 0.103
0.402TrpPro: 0.402 ± 0.085
0.256TrpGln: 0.256 ± 0.092
0.183TrpArg: 0.183 ± 0.061
0.366TrpSer: 0.366 ± 0.074
0.348TrpThr: 0.348 ± 0.078
0.311TrpVal: 0.311 ± 0.065
0.037TrpTrp: 0.037 ± 0.027
0.439TrpTyr: 0.439 ± 0.088
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.171TyrAla: 1.171 ± 0.141
1.226TyrCys: 1.226 ± 0.178
2.689TyrAsp: 2.689 ± 0.194
2.634TyrGlu: 2.634 ± 0.189
2.598TyrPhe: 2.598 ± 0.302
1.262TyrGly: 1.262 ± 0.204
0.951TyrHis: 0.951 ± 0.143
5.781TyrIle: 5.781 ± 0.516
4.775TyrLys: 4.775 ± 0.441
5.525TyrLeu: 5.525 ± 0.471
1.372TyrMet: 1.372 ± 0.174
6.074TyrAsn: 6.074 ± 0.406
1.647TyrPro: 1.647 ± 0.197
1.464TyrGln: 1.464 ± 0.154
1.336TyrArg: 1.336 ± 0.147
3.019TyrSer: 3.019 ± 0.33
2.397TyrThr: 2.397 ± 0.307
2.214TyrVal: 2.214 ± 0.264
0.293TyrTrp: 0.293 ± 0.072
3.073TyrTyr: 3.073 ± 0.34
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 160 proteins (54662 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski