Amino acid dipepetide frequency for Anaerovirgula multivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.032AlaAla: 5.032 ± 0.076
0.684AlaCys: 0.684 ± 0.025
2.827AlaAsp: 2.827 ± 0.047
4.258AlaGlu: 4.258 ± 0.064
2.812AlaPhe: 2.812 ± 0.049
4.632AlaGly: 4.632 ± 0.068
0.995AlaHis: 0.995 ± 0.025
6.262AlaIle: 6.262 ± 0.075
4.574AlaLys: 4.574 ± 0.056
6.559AlaLeu: 6.559 ± 0.077
2.034AlaMet: 2.034 ± 0.037
2.635AlaAsn: 2.635 ± 0.042
1.665AlaPro: 1.665 ± 0.035
1.73AlaGln: 1.73 ± 0.033
2.296AlaArg: 2.296 ± 0.037
3.63AlaSer: 3.63 ± 0.05
3.508AlaThr: 3.508 ± 0.127
4.993AlaVal: 4.993 ± 0.067
0.462AlaTrp: 0.462 ± 0.019
2.318AlaTyr: 2.318 ± 0.046
0.0AlaXaa: 0.0 ± 0.0
Cys
0.527CysAla: 0.527 ± 0.02
0.174CysCys: 0.174 ± 0.012
0.524CysAsp: 0.524 ± 0.019
0.59CysGlu: 0.59 ± 0.023
0.426CysPhe: 0.426 ± 0.016
0.956CysGly: 0.956 ± 0.028
0.233CysHis: 0.233 ± 0.013
0.894CysIle: 0.894 ± 0.025
0.721CysLys: 0.721 ± 0.023
0.774CysLeu: 0.774 ± 0.025
0.27CysMet: 0.27 ± 0.014
0.554CysAsn: 0.554 ± 0.019
0.466CysPro: 0.466 ± 0.02
0.317CysGln: 0.317 ± 0.015
0.379CysArg: 0.379 ± 0.015
0.721CysSer: 0.721 ± 0.02
0.49CysThr: 0.49 ± 0.02
0.582CysVal: 0.582 ± 0.023
0.066CysTrp: 0.066 ± 0.006
0.361CysTyr: 0.361 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
3.058AspAla: 3.058 ± 0.05
0.557AspCys: 0.557 ± 0.022
2.311AspAsp: 2.311 ± 0.042
4.089AspGlu: 4.089 ± 0.059
2.586AspPhe: 2.586 ± 0.045
3.169AspGly: 3.169 ± 0.055
0.949AspHis: 0.949 ± 0.029
5.632AspIle: 5.632 ± 0.065
3.98AspLys: 3.98 ± 0.049
4.765AspLeu: 4.765 ± 0.059
1.537AspMet: 1.537 ± 0.032
2.367AspAsn: 2.367 ± 0.045
1.543AspPro: 1.543 ± 0.03
1.281AspGln: 1.281 ± 0.026
2.142AspArg: 2.142 ± 0.037
2.619AspSer: 2.619 ± 0.044
2.662AspThr: 2.662 ± 0.047
3.508AspVal: 3.508 ± 0.046
0.499AspTrp: 0.499 ± 0.019
2.504AspTyr: 2.504 ± 0.047
0.0AspXaa: 0.0 ± 0.0
Glu
5.349GluAla: 5.349 ± 0.073
0.535GluCys: 0.535 ± 0.02
4.35GluAsp: 4.35 ± 0.061
8.013GluGlu: 8.013 ± 0.115
2.58GluPhe: 2.58 ± 0.045
4.991GluGly: 4.991 ± 0.067
1.081GluHis: 1.081 ± 0.027
7.63GluIle: 7.63 ± 0.085
7.657GluLys: 7.657 ± 0.083
6.737GluLeu: 6.737 ± 0.069
2.346GluMet: 2.346 ± 0.041
4.598GluAsn: 4.598 ± 0.059
1.66GluPro: 1.66 ± 0.037
1.944GluGln: 1.944 ± 0.043
2.892GluArg: 2.892 ± 0.046
3.22GluSer: 3.22 ± 0.051
3.459GluThr: 3.459 ± 0.054
5.418GluVal: 5.418 ± 0.071
0.55GluTrp: 0.55 ± 0.02
2.666GluTyr: 2.666 ± 0.043
0.0GluXaa: 0.0 ± 0.0
Phe
2.5PheAla: 2.5 ± 0.049
0.459PheCys: 0.459 ± 0.019
2.305PheAsp: 2.305 ± 0.037
2.604PheGlu: 2.604 ± 0.043
2.009PhePhe: 2.009 ± 0.047
2.838PheGly: 2.838 ± 0.046
0.81PheHis: 0.81 ± 0.024
4.114PheIle: 4.114 ± 0.063
2.885PheLys: 2.885 ± 0.044
3.997PheLeu: 3.997 ± 0.061
1.153PheMet: 1.153 ± 0.028
2.209PheAsn: 2.209 ± 0.041
1.338PhePro: 1.338 ± 0.031
1.423PheGln: 1.423 ± 0.032
1.391PheArg: 1.391 ± 0.033
2.909PheSer: 2.909 ± 0.051
2.472PheThr: 2.472 ± 0.044
2.719PheVal: 2.719 ± 0.051
0.34PheTrp: 0.34 ± 0.015
1.602PheTyr: 1.602 ± 0.035
0.0PheXaa: 0.0 ± 0.0
Gly
4.574GlyAla: 4.574 ± 0.131
0.883GlyCys: 0.883 ± 0.028
3.198GlyAsp: 3.198 ± 0.049
4.682GlyGlu: 4.682 ± 0.065
3.229GlyPhe: 3.229 ± 0.056
4.894GlyGly: 4.894 ± 0.081
1.135GlyHis: 1.135 ± 0.026
6.896GlyIle: 6.896 ± 0.076
5.208GlyLys: 5.208 ± 0.064
6.275GlyLeu: 6.275 ± 0.078
2.145GlyMet: 2.145 ± 0.044
3.178GlyAsn: 3.178 ± 0.055
1.377GlyPro: 1.377 ± 0.034
1.762GlyGln: 1.762 ± 0.038
2.521GlyArg: 2.521 ± 0.041
3.587GlySer: 3.587 ± 0.058
3.8GlyThr: 3.8 ± 0.063
4.814GlyVal: 4.814 ± 0.065
0.588GlyTrp: 0.588 ± 0.022
3.028GlyTyr: 3.028 ± 0.054
0.0GlyXaa: 0.0 ± 0.0
His
0.93HisAla: 0.93 ± 0.024
0.222HisCys: 0.222 ± 0.013
0.825HisAsp: 0.825 ± 0.026
1.137HisGlu: 1.137 ± 0.028
0.802HisPhe: 0.802 ± 0.024
1.152HisGly: 1.152 ± 0.031
0.497HisHis: 0.497 ± 0.022
1.649HisIle: 1.649 ± 0.042
1.113HisLys: 1.113 ± 0.029
1.675HisLeu: 1.675 ± 0.034
0.475HisMet: 0.475 ± 0.017
0.85HisAsn: 0.85 ± 0.025
0.861HisPro: 0.861 ± 0.029
0.663HisGln: 0.663 ± 0.025
0.76HisArg: 0.76 ± 0.025
1.034HisSer: 1.034 ± 0.028
0.858HisThr: 0.858 ± 0.024
1.039HisVal: 1.039 ± 0.027
0.176HisTrp: 0.176 ± 0.01
0.732HisTyr: 0.732 ± 0.023
0.0HisXaa: 0.0 ± 0.0
Ile
6.482IleAla: 6.482 ± 0.078
0.973IleCys: 0.973 ± 0.024
5.612IleAsp: 5.612 ± 0.057
7.454IleGlu: 7.454 ± 0.08
3.884IlePhe: 3.884 ± 0.067
6.366IleGly: 6.366 ± 0.068
1.691IleHis: 1.691 ± 0.039
8.308IleIle: 8.308 ± 0.104
6.979IleLys: 6.979 ± 0.077
8.675IleLeu: 8.675 ± 0.093
2.453IleMet: 2.453 ± 0.045
4.72IleAsn: 4.72 ± 0.063
3.652IlePro: 3.652 ± 0.052
2.867IleGln: 2.867 ± 0.045
3.371IleArg: 3.371 ± 0.05
5.917IleSer: 5.917 ± 0.075
5.162IleThr: 5.162 ± 0.073
6.036IleVal: 6.036 ± 0.066
0.586IleTrp: 0.586 ± 0.02
3.256IleTyr: 3.256 ± 0.052
0.0IleXaa: 0.0 ± 0.0
Lys
4.92LysAla: 4.92 ± 0.063
0.606LysCys: 0.606 ± 0.022
4.629LysAsp: 4.629 ± 0.059
7.99LysGlu: 7.99 ± 0.089
2.25LysPhe: 2.25 ± 0.034
4.895LysGly: 4.895 ± 0.057
1.296LysHis: 1.296 ± 0.031
7.029LysIle: 7.029 ± 0.074
6.903LysLys: 6.903 ± 0.079
6.517LysLeu: 6.517 ± 0.06
2.241LysMet: 2.241 ± 0.037
4.538LysAsn: 4.538 ± 0.064
2.083LysPro: 2.083 ± 0.036
2.449LysGln: 2.449 ± 0.043
3.071LysArg: 3.071 ± 0.056
4.125LysSer: 4.125 ± 0.057
3.981LysThr: 3.981 ± 0.05
5.109LysVal: 5.109 ± 0.066
0.591LysTrp: 0.591 ± 0.02
3.116LysTyr: 3.116 ± 0.048
0.0LysXaa: 0.0 ± 0.0
Leu
6.011LeuAla: 6.011 ± 0.071
0.914LeuCys: 0.914 ± 0.026
4.804LeuAsp: 4.804 ± 0.061
7.256LeuGlu: 7.256 ± 0.077
3.913LeuPhe: 3.913 ± 0.07
6.498LeuGly: 6.498 ± 0.079
1.49LeuHis: 1.49 ± 0.029
7.862LeuIle: 7.862 ± 0.09
7.742LeuLys: 7.742 ± 0.078
9.24LeuLeu: 9.24 ± 0.115
2.726LeuMet: 2.726 ± 0.045
4.714LeuAsn: 4.714 ± 0.058
3.296LeuPro: 3.296 ± 0.043
3.283LeuGln: 3.283 ± 0.051
3.493LeuArg: 3.493 ± 0.054
6.123LeuSer: 6.123 ± 0.07
4.807LeuThr: 4.807 ± 0.058
5.64LeuVal: 5.64 ± 0.073
0.694LeuTrp: 0.694 ± 0.024
3.197LeuTyr: 3.197 ± 0.054
0.0LeuXaa: 0.0 ± 0.0
Met
2.039MetAla: 2.039 ± 0.037
0.197MetCys: 0.197 ± 0.012
1.534MetAsp: 1.534 ± 0.031
2.333MetGlu: 2.333 ± 0.044
0.972MetPhe: 0.972 ± 0.028
2.038MetGly: 2.038 ± 0.036
0.39MetHis: 0.39 ± 0.019
2.627MetIle: 2.627 ± 0.048
2.723MetLys: 2.723 ± 0.045
2.599MetLeu: 2.599 ± 0.045
1.0MetMet: 1.0 ± 0.025
1.63MetAsn: 1.63 ± 0.032
1.035MetPro: 1.035 ± 0.03
0.864MetGln: 0.864 ± 0.025
1.008MetArg: 1.008 ± 0.024
1.545MetSer: 1.545 ± 0.031
1.463MetThr: 1.463 ± 0.029
1.899MetVal: 1.899 ± 0.031
0.162MetTrp: 0.162 ± 0.01
0.782MetTyr: 0.782 ± 0.023
0.0MetXaa: 0.0 ± 0.0
Asn
2.783AsnAla: 2.783 ± 0.047
0.556AsnCys: 0.556 ± 0.019
2.26AsnAsp: 2.26 ± 0.039
3.397AsnGlu: 3.397 ± 0.054
2.046AsnPhe: 2.046 ± 0.034
2.975AsnGly: 2.975 ± 0.048
1.115AsnHis: 1.115 ± 0.028
5.38AsnIle: 5.38 ± 0.068
4.015AsnLys: 4.015 ± 0.055
4.852AsnLeu: 4.852 ± 0.065
1.435AsnMet: 1.435 ± 0.029
3.004AsnAsn: 3.004 ± 0.054
2.244AsnPro: 2.244 ± 0.044
1.851AsnGln: 1.851 ± 0.04
2.172AsnArg: 2.172 ± 0.041
2.791AsnSer: 2.791 ± 0.048
2.78AsnThr: 2.78 ± 0.043
3.073AsnVal: 3.073 ± 0.048
0.465AsnTrp: 0.465 ± 0.016
2.156AsnTyr: 2.156 ± 0.042
0.0AsnXaa: 0.0 ± 0.0
Pro
1.876ProAla: 1.876 ± 0.036
0.312ProCys: 0.312 ± 0.016
1.622ProAsp: 1.622 ± 0.034
2.486ProGlu: 2.486 ± 0.045
1.491ProPhe: 1.491 ± 0.033
1.987ProGly: 1.987 ± 0.042
0.631ProHis: 0.631 ± 0.021
3.004ProIle: 3.004 ± 0.054
2.116ProLys: 2.116 ± 0.04
2.973ProLeu: 2.973 ± 0.042
0.837ProMet: 0.837 ± 0.021
1.518ProAsn: 1.518 ± 0.036
0.859ProPro: 0.859 ± 0.026
1.1ProGln: 1.1 ± 0.029
1.028ProArg: 1.028 ± 0.031
1.894ProSer: 1.894 ± 0.036
1.771ProThr: 1.771 ± 0.033
2.374ProVal: 2.374 ± 0.043
0.261ProTrp: 0.261 ± 0.014
1.397ProTyr: 1.397 ± 0.026
0.0ProXaa: 0.0 ± 0.0
Gln
1.873GlnAla: 1.873 ± 0.034
0.294GlnCys: 0.294 ± 0.015
1.469GlnAsp: 1.469 ± 0.035
2.766GlnGlu: 2.766 ± 0.044
1.117GlnPhe: 1.117 ± 0.027
1.881GlnGly: 1.881 ± 0.033
0.617GlnHis: 0.617 ± 0.021
2.426GlnIle: 2.426 ± 0.042
2.374GlnLys: 2.374 ± 0.04
3.177GlnLeu: 3.177 ± 0.045
0.965GlnMet: 0.965 ± 0.025
1.555GlnAsn: 1.555 ± 0.036
0.844GlnPro: 0.844 ± 0.024
1.485GlnGln: 1.485 ± 0.044
1.292GlnArg: 1.292 ± 0.031
1.636GlnSer: 1.636 ± 0.032
1.31GlnThr: 1.31 ± 0.029
1.949GlnVal: 1.949 ± 0.041
0.346GlnTrp: 0.346 ± 0.014
1.397GlnTyr: 1.397 ± 0.029
0.0GlnXaa: 0.0 ± 0.0
Arg
2.142ArgAla: 2.142 ± 0.036
0.376ArgCys: 0.376 ± 0.018
1.963ArgAsp: 1.963 ± 0.031
3.29ArgGlu: 3.29 ± 0.052
1.626ArgPhe: 1.626 ± 0.035
2.414ArgGly: 2.414 ± 0.042
0.596ArgHis: 0.596 ± 0.021
3.488ArgIle: 3.488 ± 0.05
3.227ArgLys: 3.227 ± 0.052
3.51ArgLeu: 3.51 ± 0.051
1.092ArgMet: 1.092 ± 0.025
2.044ArgAsn: 2.044 ± 0.035
1.01ArgPro: 1.01 ± 0.025
1.307ArgGln: 1.307 ± 0.027
1.762ArgArg: 1.762 ± 0.038
1.801ArgSer: 1.801 ± 0.034
1.752ArgThr: 1.752 ± 0.041
2.535ArgVal: 2.535 ± 0.044
0.33ArgTrp: 0.33 ± 0.016
1.524ArgTyr: 1.524 ± 0.034
0.0ArgXaa: 0.0 ± 0.0
Ser
3.038SerAla: 3.038 ± 0.049
0.588SerCys: 0.588 ± 0.021
2.637SerAsp: 2.637 ± 0.044
3.412SerGlu: 3.412 ± 0.054
3.012SerPhe: 3.012 ± 0.047
3.985SerGly: 3.985 ± 0.057
1.081SerHis: 1.081 ± 0.029
5.891SerIle: 5.891 ± 0.071
4.373SerLys: 4.373 ± 0.068
5.632SerLeu: 5.632 ± 0.062
1.683SerMet: 1.683 ± 0.035
2.982SerAsn: 2.982 ± 0.047
1.803SerPro: 1.803 ± 0.04
1.883SerGln: 1.883 ± 0.038
2.152SerArg: 2.152 ± 0.041
3.683SerSer: 3.683 ± 0.06
3.066SerThr: 3.066 ± 0.044
3.469SerVal: 3.469 ± 0.055
0.455SerTrp: 0.455 ± 0.019
2.331SerTyr: 2.331 ± 0.047
0.0SerXaa: 0.0 ± 0.0
Thr
3.634ThrAla: 3.634 ± 0.058
0.458ThrCys: 0.458 ± 0.017
2.475ThrAsp: 2.475 ± 0.044
3.357ThrGlu: 3.357 ± 0.046
2.228ThrPhe: 2.228 ± 0.039
4.187ThrGly: 4.187 ± 0.134
0.867ThrHis: 0.867 ± 0.023
5.073ThrIle: 5.073 ± 0.064
3.577ThrLys: 3.577 ± 0.055
4.975ThrLeu: 4.975 ± 0.057
1.384ThrMet: 1.384 ± 0.03
2.468ThrAsn: 2.468 ± 0.046
2.055ThrPro: 2.055 ± 0.04
1.367ThrGln: 1.367 ± 0.032
1.789ThrArg: 1.789 ± 0.037
3.165ThrSer: 3.165 ± 0.049
2.984ThrThr: 2.984 ± 0.054
3.809ThrVal: 3.809 ± 0.061
0.394ThrTrp: 0.394 ± 0.018
1.982ThrTyr: 1.982 ± 0.045
0.0ThrXaa: 0.0 ± 0.0
Val
4.619ValAla: 4.619 ± 0.06
0.683ValCys: 0.683 ± 0.022
3.76ValAsp: 3.76 ± 0.049
5.307ValGlu: 5.307 ± 0.064
2.925ValPhe: 2.925 ± 0.044
4.559ValGly: 4.559 ± 0.062
1.028ValHis: 1.028 ± 0.03
6.096ValIle: 6.096 ± 0.064
4.888ValLys: 4.888 ± 0.062
6.347ValLeu: 6.347 ± 0.08
1.866ValMet: 1.866 ± 0.039
3.189ValAsn: 3.189 ± 0.05
2.193ValPro: 2.193 ± 0.039
1.661ValGln: 1.661 ± 0.038
2.205ValArg: 2.205 ± 0.044
4.017ValSer: 4.017 ± 0.053
3.524ValThr: 3.524 ± 0.055
4.887ValVal: 4.887 ± 0.066
0.451ValTrp: 0.451 ± 0.018
2.337ValTyr: 2.337 ± 0.047
0.0ValXaa: 0.0 ± 0.0
Trp
0.452TrpAla: 0.452 ± 0.019
0.083TrpCys: 0.083 ± 0.007
0.43TrpAsp: 0.43 ± 0.02
0.518TrpGlu: 0.518 ± 0.019
0.351TrpPhe: 0.351 ± 0.014
0.638TrpGly: 0.638 ± 0.021
0.151TrpHis: 0.151 ± 0.009
0.695TrpIle: 0.695 ± 0.025
0.546TrpLys: 0.546 ± 0.02
0.756TrpLeu: 0.756 ± 0.024
0.237TrpMet: 0.237 ± 0.012
0.458TrpAsn: 0.458 ± 0.02
0.197TrpPro: 0.197 ± 0.011
0.302TrpGln: 0.302 ± 0.013
0.327TrpArg: 0.327 ± 0.014
0.441TrpSer: 0.441 ± 0.019
0.359TrpThr: 0.359 ± 0.016
0.51TrpVal: 0.51 ± 0.019
0.094TrpTrp: 0.094 ± 0.007
0.299TrpTyr: 0.299 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.067TyrAla: 2.067 ± 0.037
0.47TyrCys: 0.47 ± 0.017
2.221TyrAsp: 2.221 ± 0.049
2.737TyrGlu: 2.737 ± 0.049
1.818TyrPhe: 1.818 ± 0.038
2.719TyrGly: 2.719 ± 0.046
0.799TyrHis: 0.799 ± 0.022
3.487TyrIle: 3.487 ± 0.051
2.74TyrLys: 2.74 ± 0.05
3.666TyrLeu: 3.666 ± 0.056
0.961TyrMet: 0.961 ± 0.027
2.139TyrAsn: 2.139 ± 0.047
1.36TyrPro: 1.36 ± 0.032
1.234TyrGln: 1.234 ± 0.029
1.734TyrArg: 1.734 ± 0.037
2.299TyrSer: 2.299 ± 0.041
2.021TyrThr: 2.021 ± 0.041
2.178TyrVal: 2.178 ± 0.036
0.335TyrTrp: 0.335 ± 0.015
1.801TyrTyr: 1.801 ± 0.036
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5186 proteins (1509487 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski