Amino acid dipepetide frequency for Leifsonia xyli subsp. xyli (strain CTCB07)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.568AlaAla: 20.568 ± 0.304	0.692AlaCys: 0.692 ± 0.038	7.293AlaAsp: 7.293 ± 0.12	8.459AlaGlu: 8.459 ± 0.149	4.083AlaPhe: 4.083 ± 0.082	12.611AlaGly: 12.611 ± 0.186	2.324AlaHis: 2.324 ± 0.073	5.946AlaIle: 5.946 ± 0.106	3.291AlaLys: 3.291 ± 0.084	14.236AlaLeu: 14.236 ± 0.206	2.542AlaMet: 2.542 ± 0.075	2.715AlaAsn: 2.715 ± 0.071	5.964AlaPro: 5.964 ± 0.128	3.857AlaGln: 3.857 ± 0.083	8.796AlaArg: 8.796 ± 0.143	7.079AlaSer: 7.079 ± 0.108	6.935AlaThr: 6.935 ± 0.129	11.774AlaVal: 11.774 ± 0.18	1.479AlaTrp: 1.479 ± 0.057	2.346AlaTyr: 2.346 ± 0.062	0.0AlaXaa: 0.0 ± 0.0
Cys	0.758CysAla: 0.758 ± 0.038	0.056CysCys: 0.056 ± 0.009	0.31CysAsp: 0.31 ± 0.022	0.278CysGlu: 0.278 ± 0.02	0.202CysPhe: 0.202 ± 0.02	0.63CysGly: 0.63 ± 0.037	0.133CysHis: 0.133 ± 0.017	0.141CysIle: 0.141 ± 0.017	0.074CysLys: 0.074 ± 0.012	0.504CysLeu: 0.504 ± 0.03	0.099CysMet: 0.099 ± 0.013	0.104CysAsn: 0.104 ± 0.013	0.376CysPro: 0.376 ± 0.028	0.14CysGln: 0.14 ± 0.016	0.377CysArg: 0.377 ± 0.024	0.436CysSer: 0.436 ± 0.025	0.303CysThr: 0.303 ± 0.022	0.517CysVal: 0.517 ± 0.031	0.081CysTrp: 0.081 ± 0.013	0.126CysTyr: 0.126 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.546AspAla: 7.546 ± 0.123	0.244AspCys: 0.244 ± 0.022	3.413AspAsp: 3.413 ± 0.074	3.662AspGlu: 3.662 ± 0.096	1.764AspPhe: 1.764 ± 0.054	5.499AspGly: 5.499 ± 0.115	1.086AspHis: 1.086 ± 0.042	2.554AspIle: 2.554 ± 0.067	1.159AspLys: 1.159 ± 0.052	5.782AspLeu: 5.782 ± 0.109	0.667AspMet: 0.667 ± 0.032	0.967AspAsn: 0.967 ± 0.043	3.728AspPro: 3.728 ± 0.081	1.622AspGln: 1.622 ± 0.053	4.443AspArg: 4.443 ± 0.077	2.838AspSer: 2.838 ± 0.072	2.772AspThr: 2.772 ± 0.06	4.524AspVal: 4.524 ± 0.097	0.783AspTrp: 0.783 ± 0.032	1.257AspTyr: 1.257 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	6.967GluAla: 6.967 ± 0.147	0.275GluCys: 0.275 ± 0.02	2.545GluAsp: 2.545 ± 0.061	3.237GluGlu: 3.237 ± 0.087	1.774GluPhe: 1.774 ± 0.062	3.997GluGly: 3.997 ± 0.087	1.285GluHis: 1.285 ± 0.047	2.786GluIle: 2.786 ± 0.077	1.676GluLys: 1.676 ± 0.061	6.539GluLeu: 6.539 ± 0.127	0.896GluMet: 0.896 ± 0.038	1.332GluAsn: 1.332 ± 0.042	3.037GluPro: 3.037 ± 0.086	1.998GluGln: 1.998 ± 0.074	5.582GluArg: 5.582 ± 0.118	2.949GluSer: 2.949 ± 0.078	3.416GluThr: 3.416 ± 0.079	4.361GluVal: 4.361 ± 0.098	0.753GluTrp: 0.753 ± 0.035	1.117GluTyr: 1.117 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	4.388PheAla: 4.388 ± 0.104	0.194PheCys: 0.194 ± 0.019	2.21PheAsp: 2.21 ± 0.06	1.876PheGlu: 1.876 ± 0.062	1.157PhePhe: 1.157 ± 0.052	3.542PheGly: 3.542 ± 0.078	0.574PheHis: 0.574 ± 0.033	1.095PheIle: 1.095 ± 0.046	0.574PheLys: 0.574 ± 0.033	3.0PheLeu: 3.0 ± 0.091	0.43PheMet: 0.43 ± 0.028	0.633PheAsn: 0.633 ± 0.032	1.42PhePro: 1.42 ± 0.048	0.849PheGln: 0.849 ± 0.046	1.956PheArg: 1.956 ± 0.058	1.966PheSer: 1.966 ± 0.047	1.942PheThr: 1.942 ± 0.061	2.88PheVal: 2.88 ± 0.079	0.453PheTrp: 0.453 ± 0.029	0.633PheTyr: 0.633 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	10.45GlyAla: 10.45 ± 0.169	0.625GlyCys: 0.625 ± 0.038	4.896GlyAsp: 4.896 ± 0.096	5.191GlyGlu: 5.191 ± 0.108	3.298GlyPhe: 3.298 ± 0.075	7.812GlyGly: 7.812 ± 0.146	1.881GlyHis: 1.881 ± 0.058	4.516GlyIle: 4.516 ± 0.098	2.759GlyLys: 2.759 ± 0.071	8.727GlyLeu: 8.727 ± 0.119	2.065GlyMet: 2.065 ± 0.057	1.843GlyAsn: 1.843 ± 0.052	3.886GlyPro: 3.886 ± 0.08	2.735GlyGln: 2.735 ± 0.073	6.793GlyArg: 6.793 ± 0.116	5.942GlySer: 5.942 ± 0.105	5.467GlyThr: 5.467 ± 0.1	8.001GlyVal: 8.001 ± 0.119	1.565GlyTrp: 1.565 ± 0.051	2.198GlyTyr: 2.198 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	2.052HisAla: 2.052 ± 0.065	0.135HisCys: 0.135 ± 0.016	1.225HisAsp: 1.225 ± 0.049	1.085HisGlu: 1.085 ± 0.046	0.49HisPhe: 0.49 ± 0.028	1.789HisGly: 1.789 ± 0.048	0.43HisHis: 0.43 ± 0.035	0.869HisIle: 0.869 ± 0.034	0.362HisLys: 0.362 ± 0.028	1.922HisLeu: 1.922 ± 0.058	0.264HisMet: 0.264 ± 0.024	0.392HisAsn: 0.392 ± 0.027	1.455HisPro: 1.455 ± 0.049	0.515HisGln: 0.515 ± 0.027	1.617HisArg: 1.617 ± 0.06	1.167HisSer: 1.167 ± 0.048	1.102HisThr: 1.102 ± 0.044	1.29HisVal: 1.29 ± 0.045	0.275HisTrp: 0.275 ± 0.022	0.47HisTyr: 0.47 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	7.059IleAla: 7.059 ± 0.133	0.231IleCys: 0.231 ± 0.019	3.05IleAsp: 3.05 ± 0.075	2.87IleGlu: 2.87 ± 0.081	1.09IlePhe: 1.09 ± 0.044	4.76IleGly: 4.76 ± 0.107	0.758IleHis: 0.758 ± 0.038	1.492IleIle: 1.492 ± 0.062	0.982IleLys: 0.982 ± 0.05	3.829IleLeu: 3.829 ± 0.083	0.64IleMet: 0.64 ± 0.038	0.926IleAsn: 0.926 ± 0.04	2.473IlePro: 2.473 ± 0.067	1.139IleGln: 1.139 ± 0.045	2.875IleArg: 2.875 ± 0.073	2.22IleSer: 2.22 ± 0.062	2.505IleThr: 2.505 ± 0.066	5.117IleVal: 5.117 ± 0.103	0.468IleTrp: 0.468 ± 0.031	0.718IleTyr: 0.718 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	2.909LysAla: 2.909 ± 0.079	0.088LysCys: 0.088 ± 0.012	1.395LysAsp: 1.395 ± 0.05	1.085LysGlu: 1.085 ± 0.042	0.534LysPhe: 0.534 ± 0.028	1.833LysGly: 1.833 ± 0.07	0.542LysHis: 0.542 ± 0.034	1.157LysIle: 1.157 ± 0.051	0.975LysLys: 0.975 ± 0.05	2.316LysLeu: 2.316 ± 0.068	0.428LysMet: 0.428 ± 0.027	0.724LysAsn: 0.724 ± 0.037	1.546LysPro: 1.546 ± 0.053	0.871LysGln: 0.871 ± 0.038	2.063LysArg: 2.063 ± 0.069	1.415LysSer: 1.415 ± 0.051	1.816LysThr: 1.816 ± 0.056	1.834LysVal: 1.834 ± 0.075	0.288LysTrp: 0.288 ± 0.021	0.534LysTyr: 0.534 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	14.637LeuAla: 14.637 ± 0.184	0.59LeuCys: 0.59 ± 0.036	6.359LeuAsp: 6.359 ± 0.101	4.87LeuGlu: 4.87 ± 0.102	3.123LeuPhe: 3.123 ± 0.094	9.301LeuGly: 9.301 ± 0.147	1.828LeuHis: 1.828 ± 0.058	4.588LeuIle: 4.588 ± 0.102	2.144LeuLys: 2.144 ± 0.07	10.682LeuLeu: 10.682 ± 0.179	1.502LeuMet: 1.502 ± 0.055	1.959LeuAsn: 1.959 ± 0.067	5.756LeuPro: 5.756 ± 0.106	2.383LeuGln: 2.383 ± 0.063	7.62LeuArg: 7.62 ± 0.116	6.369LeuSer: 6.369 ± 0.107	6.825LeuThr: 6.825 ± 0.114	8.829LeuVal: 8.829 ± 0.138	1.243LeuTrp: 1.243 ± 0.049	1.681LeuTyr: 1.681 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.035MetAla: 2.035 ± 0.062	0.098MetCys: 0.098 ± 0.013	0.785MetAsp: 0.785 ± 0.04	0.68MetGlu: 0.68 ± 0.034	0.514MetPhe: 0.514 ± 0.031	1.196MetGly: 1.196 ± 0.043	0.3MetHis: 0.3 ± 0.021	0.867MetIle: 0.867 ± 0.036	0.495MetLys: 0.495 ± 0.031	1.833MetLeu: 1.833 ± 0.057	0.342MetMet: 0.342 ± 0.024	0.462MetAsn: 0.462 ± 0.029	1.066MetPro: 1.066 ± 0.04	0.519MetGln: 0.519 ± 0.025	1.491MetArg: 1.491 ± 0.054	1.349MetSer: 1.349 ± 0.049	1.56MetThr: 1.56 ± 0.055	1.4MetVal: 1.4 ± 0.053	0.165MetTrp: 0.165 ± 0.017	0.303MetTyr: 0.303 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	2.761AsnAla: 2.761 ± 0.07	0.136AsnCys: 0.136 ± 0.017	1.113AsnAsp: 1.113 ± 0.045	1.075AsnGlu: 1.075 ± 0.049	0.62AsnPhe: 0.62 ± 0.033	2.252AsnGly: 2.252 ± 0.061	0.372AsnHis: 0.372 ± 0.022	0.972AsnIle: 0.972 ± 0.045	0.526AsnLys: 0.526 ± 0.031	1.998AsnLeu: 1.998 ± 0.057	0.33AsnMet: 0.33 ± 0.022	0.515AsnAsn: 0.515 ± 0.032	1.686AsnPro: 1.686 ± 0.054	0.64AsnGln: 0.64 ± 0.031	1.553AsnArg: 1.553 ± 0.057	1.038AsnSer: 1.038 ± 0.044	1.299AsnThr: 1.299 ± 0.052	1.728AsnVal: 1.728 ± 0.065	0.27AsnTrp: 0.27 ± 0.02	0.515AsnTyr: 0.515 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	7.327ProAla: 7.327 ± 0.14	0.258ProCys: 0.258 ± 0.022	3.391ProAsp: 3.391 ± 0.085	3.813ProGlu: 3.813 ± 0.079	1.669ProPhe: 1.669 ± 0.041	5.499ProGly: 5.499 ± 0.103	1.027ProHis: 1.027 ± 0.045	2.134ProIle: 2.134 ± 0.063	1.169ProLys: 1.169 ± 0.047	4.94ProLeu: 4.94 ± 0.103	0.871ProMet: 0.871 ± 0.04	1.191ProAsn: 1.191 ± 0.045	2.505ProPro: 2.505 ± 0.085	1.486ProGln: 1.486 ± 0.048	3.288ProArg: 3.288 ± 0.073	3.285ProSer: 3.285 ± 0.08	2.949ProThr: 2.949 ± 0.077	5.035ProVal: 5.035 ± 0.105	0.736ProTrp: 0.736 ± 0.041	1.039ProTyr: 1.039 ± 0.045	0.0ProXaa: 0.0 ± 0.0
Gln	3.493GlnAla: 3.493 ± 0.087	0.104GlnCys: 0.104 ± 0.013	1.268GlnAsp: 1.268 ± 0.049	1.391GlnGlu: 1.391 ± 0.054	0.852GlnPhe: 0.852 ± 0.04	2.092GlnGly: 2.092 ± 0.061	0.64GlnHis: 0.64 ± 0.035	1.491GlnIle: 1.491 ± 0.052	0.889GlnLys: 0.889 ± 0.04	3.409GlnLeu: 3.409 ± 0.072	0.472GlnMet: 0.472 ± 0.03	0.766GlnAsn: 0.766 ± 0.042	1.59GlnPro: 1.59 ± 0.059	1.272GlnGln: 1.272 ± 0.052	2.596GlnArg: 2.596 ± 0.075	1.597GlnSer: 1.597 ± 0.054	1.684GlnThr: 1.684 ± 0.053	2.299GlnVal: 2.299 ± 0.06	0.403GlnTrp: 0.403 ± 0.033	0.637GlnTyr: 0.637 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	8.643ArgAla: 8.643 ± 0.142	0.446ArgCys: 0.446 ± 0.026	3.985ArgAsp: 3.985 ± 0.095	4.538ArgGlu: 4.538 ± 0.101	2.545ArgPhe: 2.545 ± 0.067	5.579ArgGly: 5.579 ± 0.09	1.541ArgHis: 1.541 ± 0.053	3.778ArgIle: 3.778 ± 0.087	1.807ArgLys: 1.807 ± 0.054	7.753ArgLeu: 7.753 ± 0.125	1.748ArgMet: 1.748 ± 0.055	1.602ArgAsn: 1.602 ± 0.047	3.923ArgPro: 3.923 ± 0.096	2.222ArgGln: 2.222 ± 0.057	6.552ArgArg: 6.552 ± 0.143	4.649ArgSer: 4.649 ± 0.091	4.379ArgThr: 4.379 ± 0.1	6.015ArgVal: 6.015 ± 0.11	1.083ArgTrp: 1.083 ± 0.046	1.558ArgTyr: 1.558 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	7.746SerAla: 7.746 ± 0.134	0.355SerCys: 0.355 ± 0.025	3.008SerAsp: 3.008 ± 0.084	2.831SerGlu: 2.831 ± 0.078	1.966SerPhe: 1.966 ± 0.069	6.522SerGly: 6.522 ± 0.112	1.024SerHis: 1.024 ± 0.04	2.463SerIle: 2.463 ± 0.07	1.275SerLys: 1.275 ± 0.046	5.745SerLeu: 5.745 ± 0.103	1.105SerMet: 1.105 ± 0.043	1.174SerAsn: 1.174 ± 0.048	3.247SerPro: 3.247 ± 0.074	1.607SerGln: 1.607 ± 0.054	4.197SerArg: 4.197 ± 0.092	3.647SerSer: 3.647 ± 0.089	3.529SerThr: 3.529 ± 0.079	5.083SerVal: 5.083 ± 0.105	0.96SerTrp: 0.96 ± 0.047	1.255SerTyr: 1.255 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	8.152ThrAla: 8.152 ± 0.144	0.288ThrCys: 0.288 ± 0.023	3.165ThrAsp: 3.165 ± 0.077	3.0ThrGlu: 3.0 ± 0.073	1.784ThrPhe: 1.784 ± 0.057	6.084ThrGly: 6.084 ± 0.104	1.041ThrHis: 1.041 ± 0.039	2.961ThrIle: 2.961 ± 0.076	1.327ThrLys: 1.327 ± 0.057	5.956ThrLeu: 5.956 ± 0.116	1.021ThrMet: 1.021 ± 0.041	1.223ThrAsn: 1.223 ± 0.04	3.766ThrPro: 3.766 ± 0.085	1.508ThrGln: 1.508 ± 0.054	3.776ThrArg: 3.776 ± 0.089	3.315ThrSer: 3.315 ± 0.078	3.601ThrThr: 3.601 ± 0.087	6.163ThrVal: 6.163 ± 0.114	0.761ThrTrp: 0.761 ± 0.037	1.036ThrTyr: 1.036 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	11.548ValAla: 11.548 ± 0.151	0.608ValCys: 0.608 ± 0.032	5.085ValAsp: 5.085 ± 0.102	4.876ValGlu: 4.876 ± 0.097	3.072ValPhe: 3.072 ± 0.076	6.695ValGly: 6.695 ± 0.136	1.568ValHis: 1.568 ± 0.048	4.093ValIle: 4.093 ± 0.096	2.077ValLys: 2.077 ± 0.058	9.214ValLeu: 9.214 ± 0.15	1.447ValMet: 1.447 ± 0.049	1.907ValAsn: 1.907 ± 0.063	4.528ValPro: 4.528 ± 0.104	2.407ValGln: 2.407 ± 0.061	6.077ValArg: 6.077 ± 0.117	5.435ValSer: 5.435 ± 0.1	5.744ValThr: 5.744 ± 0.109	8.363ValVal: 8.363 ± 0.143	1.157ValTrp: 1.157 ± 0.045	1.726ValTyr: 1.726 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	1.551TrpAla: 1.551 ± 0.06	0.096TrpCys: 0.096 ± 0.013	0.6TrpAsp: 0.6 ± 0.037	0.59TrpGlu: 0.59 ± 0.031	0.529TrpPhe: 0.529 ± 0.032	0.962TrpGly: 0.962 ± 0.036	0.258TrpHis: 0.258 ± 0.021	0.568TrpIle: 0.568 ± 0.036	0.339TrpLys: 0.339 ± 0.025	1.684TrpLeu: 1.684 ± 0.059	0.317TrpMet: 0.317 ± 0.026	0.453TrpAsn: 0.453 ± 0.03	0.665TrpPro: 0.665 ± 0.034	0.524TrpGln: 0.524 ± 0.03	1.09TrpArg: 1.09 ± 0.048	0.886TrpSer: 0.886 ± 0.039	0.869TrpThr: 0.869 ± 0.039	0.942TrpVal: 0.942 ± 0.038	0.307TrpTrp: 0.307 ± 0.025	0.261TrpTyr: 0.261 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.402TyrAla: 2.402 ± 0.07	0.128TyrCys: 0.128 ± 0.014	1.214TyrAsp: 1.214 ± 0.05	1.113TyrGlu: 1.113 ± 0.046	0.707TyrPhe: 0.707 ± 0.035	1.996TyrGly: 1.996 ± 0.066	0.291TyrHis: 0.291 ± 0.022	0.731TyrIle: 0.731 ± 0.04	0.451TyrLys: 0.451 ± 0.032	2.22TyrLeu: 2.22 ± 0.067	0.271TyrMet: 0.271 ± 0.022	0.509TyrAsn: 0.509 ± 0.033	0.995TyrPro: 0.995 ± 0.047	0.654TyrGln: 0.654 ± 0.038	1.605TyrArg: 1.605 ± 0.053	1.159TyrSer: 1.159 ± 0.045	1.231TyrThr: 1.231 ± 0.051	1.472TyrVal: 1.472 ± 0.046	0.259TyrTrp: 0.259 ± 0.024	0.401TyrTyr: 0.401 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2001 proteins (593693 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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