Amino acid dipepetide frequency for Parasphingopyxis lamellibrachiae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.292AlaAla: 16.292 ± 0.198	1.026AlaCys: 1.026 ± 0.035	7.578AlaAsp: 7.578 ± 0.107	8.506AlaGlu: 8.506 ± 0.112	4.356AlaPhe: 4.356 ± 0.075	10.42AlaGly: 10.42 ± 0.142	2.126AlaHis: 2.126 ± 0.049	7.371AlaIle: 7.371 ± 0.104	3.66AlaLys: 3.66 ± 0.081	12.922AlaLeu: 12.922 ± 0.168	3.847AlaMet: 3.847 ± 0.069	3.225AlaAsn: 3.225 ± 0.07	5.321AlaPro: 5.321 ± 0.077	4.015AlaGln: 4.015 ± 0.07	8.689AlaArg: 8.689 ± 0.128	6.172AlaSer: 6.172 ± 0.091	5.857AlaThr: 5.857 ± 0.097	7.758AlaVal: 7.758 ± 0.109	1.401AlaTrp: 1.401 ± 0.044	2.515AlaTyr: 2.515 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.989CysAla: 0.989 ± 0.031	0.104CysCys: 0.104 ± 0.012	0.553CysAsp: 0.553 ± 0.027	0.477CysGlu: 0.477 ± 0.026	0.332CysPhe: 0.332 ± 0.022	0.917CysGly: 0.917 ± 0.038	0.238CysHis: 0.238 ± 0.021	0.425CysIle: 0.425 ± 0.024	0.165CysLys: 0.165 ± 0.013	0.687CysLeu: 0.687 ± 0.028	0.168CysMet: 0.168 ± 0.012	0.246CysAsn: 0.246 ± 0.018	0.47CysPro: 0.47 ± 0.029	0.237CysGln: 0.237 ± 0.016	0.563CysArg: 0.563 ± 0.028	0.497CysSer: 0.497 ± 0.024	0.414CysThr: 0.414 ± 0.022	0.53CysVal: 0.53 ± 0.024	0.121CysTrp: 0.121 ± 0.013	0.189CysTyr: 0.189 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.462AspAla: 7.462 ± 0.116	0.553AspCys: 0.553 ± 0.028	3.789AspAsp: 3.789 ± 0.074	4.183AspGlu: 4.183 ± 0.072	2.418AspPhe: 2.418 ± 0.049	5.847AspGly: 5.847 ± 0.097	1.329AspHis: 1.329 ± 0.046	3.822AspIle: 3.822 ± 0.074	1.596AspLys: 1.596 ± 0.047	5.436AspLeu: 5.436 ± 0.085	1.642AspMet: 1.642 ± 0.04	1.56AspAsn: 1.56 ± 0.046	3.784AspPro: 3.784 ± 0.072	1.823AspGln: 1.823 ± 0.052	4.848AspArg: 4.848 ± 0.082	2.865AspSer: 2.865 ± 0.058	3.041AspThr: 3.041 ± 0.058	3.871AspVal: 3.871 ± 0.064	1.189AspTrp: 1.189 ± 0.04	1.744AspTyr: 1.744 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	8.603GluAla: 8.603 ± 0.125	0.368GluCys: 0.368 ± 0.021	3.577GluAsp: 3.577 ± 0.07	4.457GluGlu: 4.457 ± 0.079	1.947GluPhe: 1.947 ± 0.055	4.944GluGly: 4.944 ± 0.09	1.182GluHis: 1.182 ± 0.04	3.904GluIle: 3.904 ± 0.072	2.323GluLys: 2.323 ± 0.064	5.548GluLeu: 5.548 ± 0.084	1.844GluMet: 1.844 ± 0.057	2.085GluAsn: 2.085 ± 0.054	3.088GluPro: 3.088 ± 0.066	2.434GluGln: 2.434 ± 0.061	5.401GluArg: 5.401 ± 0.085	2.955GluSer: 2.955 ± 0.059	4.249GluThr: 4.249 ± 0.073	3.494GluVal: 3.494 ± 0.061	0.845GluTrp: 0.845 ± 0.028	1.191GluTyr: 1.191 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	4.79PheAla: 4.79 ± 0.072	0.368PheCys: 0.368 ± 0.021	2.847PheAsp: 2.847 ± 0.058	2.448PheGlu: 2.448 ± 0.056	1.449PhePhe: 1.449 ± 0.045	3.834PheGly: 3.834 ± 0.071	0.709PheHis: 0.709 ± 0.029	1.652PheIle: 1.652 ± 0.045	0.78PheLys: 0.78 ± 0.035	3.316PheLeu: 3.316 ± 0.07	0.768PheMet: 0.768 ± 0.029	1.09PheAsn: 1.09 ± 0.042	1.502PhePro: 1.502 ± 0.041	0.913PheGln: 0.913 ± 0.032	2.297PheArg: 2.297 ± 0.055	2.342PheSer: 2.342 ± 0.064	2.079PheThr: 2.079 ± 0.045	2.663PheVal: 2.663 ± 0.055	0.58PheTrp: 0.58 ± 0.027	0.962PheTyr: 0.962 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	9.104GlyAla: 9.104 ± 0.117	0.878GlyCys: 0.878 ± 0.037	5.39GlyAsp: 5.39 ± 0.083	5.882GlyGlu: 5.882 ± 0.088	3.709GlyPhe: 3.709 ± 0.076	7.919GlyGly: 7.919 ± 0.173	1.866GlyHis: 1.866 ± 0.058	4.881GlyIle: 4.881 ± 0.086	2.998GlyLys: 2.998 ± 0.066	8.42GlyLeu: 8.42 ± 0.107	2.512GlyMet: 2.512 ± 0.057	2.47GlyAsn: 2.47 ± 0.073	3.567GlyPro: 3.567 ± 0.062	3.041GlyGln: 3.041 ± 0.062	5.954GlyArg: 5.954 ± 0.101	4.967GlySer: 4.967 ± 0.095	4.757GlyThr: 4.757 ± 0.093	5.641GlyVal: 5.641 ± 0.09	1.582GlyTrp: 1.582 ± 0.046	2.32GlyTyr: 2.32 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	2.12HisAla: 2.12 ± 0.052	0.268HisCys: 0.268 ± 0.016	1.299HisAsp: 1.299 ± 0.043	1.096HisGlu: 1.096 ± 0.037	0.839HisPhe: 0.839 ± 0.03	1.93HisGly: 1.93 ± 0.057	0.552HisHis: 0.552 ± 0.027	1.145HisIle: 1.145 ± 0.034	0.502HisLys: 0.502 ± 0.024	1.76HisLeu: 1.76 ± 0.054	0.479HisMet: 0.479 ± 0.024	0.54HisAsn: 0.54 ± 0.024	1.271HisPro: 1.271 ± 0.044	0.547HisGln: 0.547 ± 0.023	1.438HisArg: 1.438 ± 0.043	0.98HisSer: 0.98 ± 0.034	0.679HisThr: 0.679 ± 0.03	1.322HisVal: 1.322 ± 0.045	0.348HisTrp: 0.348 ± 0.02	0.581HisTyr: 0.581 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	8.403IleAla: 8.403 ± 0.114	0.51IleCys: 0.51 ± 0.022	4.229IleAsp: 4.229 ± 0.078	4.075IleGlu: 4.075 ± 0.072	1.924IlePhe: 1.924 ± 0.054	5.629IleGly: 5.629 ± 0.078	0.917IleHis: 0.917 ± 0.032	2.574IleIle: 2.574 ± 0.07	1.159IleLys: 1.159 ± 0.046	4.81IleLeu: 4.81 ± 0.075	1.118IleMet: 1.118 ± 0.04	1.419IleAsn: 1.419 ± 0.042	2.486IlePro: 2.486 ± 0.051	1.277IleGln: 1.277 ± 0.038	3.415IleArg: 3.415 ± 0.06	3.088IleSer: 3.088 ± 0.062	2.812IleThr: 2.812 ± 0.06	4.682IleVal: 4.682 ± 0.07	0.717IleTrp: 0.717 ± 0.028	1.085IleTyr: 1.085 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	3.614LysAla: 3.614 ± 0.082	0.168LysCys: 0.168 ± 0.014	1.399LysAsp: 1.399 ± 0.045	1.395LysGlu: 1.395 ± 0.047	0.842LysPhe: 0.842 ± 0.034	2.223LysGly: 2.223 ± 0.053	0.565LysHis: 0.565 ± 0.033	1.571LysIle: 1.571 ± 0.051	1.288LysLys: 1.288 ± 0.05	2.974LysLeu: 2.974 ± 0.072	0.788LysMet: 0.788 ± 0.033	0.783LysAsn: 0.783 ± 0.033	1.713LysPro: 1.713 ± 0.051	0.872LysGln: 0.872 ± 0.033	2.228LysArg: 2.228 ± 0.051	1.64LysSer: 1.64 ± 0.047	1.779LysThr: 1.779 ± 0.056	1.783LysVal: 1.783 ± 0.053	0.339LysTrp: 0.339 ± 0.021	0.582LysTyr: 0.582 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	12.715LeuAla: 12.715 ± 0.139	0.779LeuCys: 0.779 ± 0.035	6.182LeuAsp: 6.182 ± 0.091	5.684LeuGlu: 5.684 ± 0.085	3.784LeuPhe: 3.784 ± 0.074	8.079LeuGly: 8.079 ± 0.12	1.729LeuHis: 1.729 ± 0.045	5.235LeuIle: 5.235 ± 0.101	2.652LeuLys: 2.652 ± 0.068	9.047LeuLeu: 9.047 ± 0.135	2.116LeuMet: 2.116 ± 0.049	2.624LeuAsn: 2.624 ± 0.058	5.004LeuPro: 5.004 ± 0.078	2.422LeuGln: 2.422 ± 0.056	6.081LeuArg: 6.081 ± 0.078	5.881LeuSer: 5.881 ± 0.086	5.295LeuThr: 5.295 ± 0.084	6.816LeuVal: 6.816 ± 0.089	1.184LeuTrp: 1.184 ± 0.04	1.982LeuTyr: 1.982 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.4MetAla: 3.4 ± 0.064	0.174MetCys: 0.174 ± 0.013	1.25MetAsp: 1.25 ± 0.039	1.345MetGlu: 1.345 ± 0.036	0.745MetPhe: 0.745 ± 0.031	1.942MetGly: 1.942 ± 0.054	0.488MetHis: 0.488 ± 0.027	1.512MetIle: 1.512 ± 0.043	0.884MetLys: 0.884 ± 0.032	2.679MetLeu: 2.679 ± 0.051	0.648MetMet: 0.648 ± 0.024	0.752MetAsn: 0.752 ± 0.029	1.543MetPro: 1.543 ± 0.038	0.808MetGln: 0.808 ± 0.029	1.924MetArg: 1.924 ± 0.044	1.538MetSer: 1.538 ± 0.044	1.935MetThr: 1.935 ± 0.051	1.672MetVal: 1.672 ± 0.05	0.227MetTrp: 0.227 ± 0.017	0.279MetTyr: 0.279 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.394AsnAla: 3.394 ± 0.073	0.261AsnCys: 0.261 ± 0.019	1.581AsnAsp: 1.581 ± 0.043	1.386AsnGlu: 1.386 ± 0.041	1.114AsnPhe: 1.114 ± 0.04	2.64AsnGly: 2.64 ± 0.076	0.524AsnHis: 0.524 ± 0.028	1.634AsnIle: 1.634 ± 0.048	0.603AsnLys: 0.603 ± 0.028	2.548AsnLeu: 2.548 ± 0.055	0.67AsnMet: 0.67 ± 0.026	0.726AsnAsn: 0.726 ± 0.034	1.925AsnPro: 1.925 ± 0.052	0.821AsnGln: 0.821 ± 0.032	2.189AsnArg: 2.189 ± 0.061	1.455AsnSer: 1.455 ± 0.043	1.125AsnThr: 1.125 ± 0.038	1.937AsnVal: 1.937 ± 0.047	0.5AsnTrp: 0.5 ± 0.024	0.753AsnTyr: 0.753 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	5.826ProAla: 5.826 ± 0.084	0.331ProCys: 0.331 ± 0.021	4.024ProAsp: 4.024 ± 0.066	4.185ProGlu: 4.185 ± 0.069	1.9ProPhe: 1.9 ± 0.053	4.603ProGly: 4.603 ± 0.079	0.992ProHis: 0.992 ± 0.035	2.566ProIle: 2.566 ± 0.054	1.412ProLys: 1.412 ± 0.052	4.591ProLeu: 4.591 ± 0.072	1.219ProMet: 1.219 ± 0.041	1.408ProAsn: 1.408 ± 0.045	2.689ProPro: 2.689 ± 0.091	1.5ProGln: 1.5 ± 0.038	2.685ProArg: 2.685 ± 0.056	2.589ProSer: 2.589 ± 0.056	2.314ProThr: 2.314 ± 0.046	4.091ProVal: 4.091 ± 0.065	0.62ProTrp: 0.62 ± 0.027	1.083ProTyr: 1.083 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.774GlnAla: 3.774 ± 0.073	0.26GlnCys: 0.26 ± 0.018	1.464GlnAsp: 1.464 ± 0.042	1.468GlnGlu: 1.468 ± 0.042	1.12GlnPhe: 1.12 ± 0.033	2.364GlnGly: 2.364 ± 0.056	0.613GlnHis: 0.613 ± 0.025	1.886GlnIle: 1.886 ± 0.049	0.885GlnLys: 0.885 ± 0.036	3.021GlnLeu: 3.021 ± 0.063	0.888GlnMet: 0.888 ± 0.03	0.846GlnAsn: 0.846 ± 0.034	1.628GlnPro: 1.628 ± 0.045	1.122GlnGln: 1.122 ± 0.044	2.341GlnArg: 2.341 ± 0.055	1.911GlnSer: 1.911 ± 0.049	1.713GlnThr: 1.713 ± 0.047	2.004GlnVal: 2.004 ± 0.049	0.445GlnTrp: 0.445 ± 0.021	0.599GlnTyr: 0.599 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	7.85ArgAla: 7.85 ± 0.107	0.516ArgCys: 0.516 ± 0.023	4.307ArgAsp: 4.307 ± 0.067	4.576ArgGlu: 4.576 ± 0.073	3.053ArgPhe: 3.053 ± 0.061	4.892ArgGly: 4.892 ± 0.075	1.576ArgHis: 1.576 ± 0.046	4.288ArgIle: 4.288 ± 0.076	2.218ArgLys: 2.218 ± 0.053	7.402ArgLeu: 7.402 ± 0.104	1.926ArgMet: 1.926 ± 0.049	2.153ArgAsn: 2.153 ± 0.049	3.387ArgPro: 3.387 ± 0.065	2.267ArgGln: 2.267 ± 0.055	5.252ArgArg: 5.252 ± 0.102	3.81ArgSer: 3.81 ± 0.067	3.331ArgThr: 3.331 ± 0.066	4.329ArgVal: 4.329 ± 0.075	1.175ArgTrp: 1.175 ± 0.036	1.982ArgTyr: 1.982 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.402SerAla: 6.402 ± 0.101	0.466SerCys: 0.466 ± 0.023	3.556SerAsp: 3.556 ± 0.073	3.421SerGlu: 3.421 ± 0.062	2.246SerPhe: 2.246 ± 0.056	5.769SerGly: 5.769 ± 0.089	1.083SerHis: 1.083 ± 0.039	2.925SerIle: 2.925 ± 0.058	1.46SerLys: 1.46 ± 0.043	5.117SerLeu: 5.117 ± 0.089	1.33SerMet: 1.33 ± 0.04	1.542SerAsn: 1.542 ± 0.042	2.733SerPro: 2.733 ± 0.058	1.591SerGln: 1.591 ± 0.041	3.638SerArg: 3.638 ± 0.061	3.031SerSer: 3.031 ± 0.068	2.56SerThr: 2.56 ± 0.056	3.694SerVal: 3.694 ± 0.062	0.843SerTrp: 0.843 ± 0.03	1.364SerTyr: 1.364 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	6.129ThrAla: 6.129 ± 0.094	0.385ThrCys: 0.385 ± 0.02	3.164ThrAsp: 3.164 ± 0.062	3.008ThrGlu: 3.008 ± 0.055	1.812ThrPhe: 1.812 ± 0.045	5.461ThrGly: 5.461 ± 0.089	0.944ThrHis: 0.944 ± 0.037	3.268ThrIle: 3.268 ± 0.066	1.266ThrLys: 1.266 ± 0.042	5.644ThrLeu: 5.644 ± 0.077	1.236ThrMet: 1.236 ± 0.039	1.37ThrAsn: 1.37 ± 0.046	3.219ThrPro: 3.219 ± 0.062	1.48ThrGln: 1.48 ± 0.043	3.244ThrArg: 3.244 ± 0.063	2.56ThrSer: 2.56 ± 0.058	2.547ThrThr: 2.547 ± 0.061	4.103ThrVal: 4.103 ± 0.073	0.523ThrTrp: 0.523 ± 0.022	1.147ThrTyr: 1.147 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	8.208ValAla: 8.208 ± 0.096	0.551ValCys: 0.551 ± 0.027	4.362ValAsp: 4.362 ± 0.066	4.839ValGlu: 4.839 ± 0.084	2.299ValPhe: 2.299 ± 0.053	5.318ValGly: 5.318 ± 0.089	1.409ValHis: 1.409 ± 0.04	3.853ValIle: 3.853 ± 0.069	1.746ValLys: 1.746 ± 0.05	5.546ValLeu: 5.546 ± 0.086	1.699ValMet: 1.699 ± 0.043	1.904ValAsn: 1.904 ± 0.047	3.587ValPro: 3.587 ± 0.059	1.93ValGln: 1.93 ± 0.047	4.802ValArg: 4.802 ± 0.083	4.279ValSer: 4.279 ± 0.068	4.182ValThr: 4.182 ± 0.064	4.646ValVal: 4.646 ± 0.075	0.802ValTrp: 0.802 ± 0.033	1.428ValTyr: 1.428 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.32TrpAla: 1.32 ± 0.04	0.116TrpCys: 0.116 ± 0.012	0.681TrpAsp: 0.681 ± 0.025	0.696TrpGlu: 0.696 ± 0.031	0.562TrpPhe: 0.562 ± 0.026	0.944TrpGly: 0.944 ± 0.033	0.356TrpHis: 0.356 ± 0.018	0.777TrpIle: 0.777 ± 0.029	0.449TrpLys: 0.449 ± 0.025	1.694TrpLeu: 1.694 ± 0.049	0.407TrpMet: 0.407 ± 0.023	0.47TrpAsn: 0.47 ± 0.023	0.69TrpPro: 0.69 ± 0.031	0.58TrpGln: 0.58 ± 0.025	1.278TrpArg: 1.278 ± 0.044	0.881TrpSer: 0.881 ± 0.028	0.776TrpThr: 0.776 ± 0.03	0.83TrpVal: 0.83 ± 0.031	0.22TrpTrp: 0.22 ± 0.017	0.319TrpTyr: 0.319 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.662TyrAla: 2.662 ± 0.052	0.239TyrCys: 0.239 ± 0.017	1.571TyrAsp: 1.571 ± 0.045	1.312TyrGlu: 1.312 ± 0.035	0.939TyrPhe: 0.939 ± 0.032	2.185TyrGly: 2.185 ± 0.052	0.497TyrHis: 0.497 ± 0.026	1.041TyrIle: 1.041 ± 0.038	0.499TyrLys: 0.499 ± 0.022	2.129TyrLeu: 2.129 ± 0.05	0.436TyrMet: 0.436 ± 0.019	0.573TyrAsn: 0.573 ± 0.026	1.021TyrPro: 1.021 ± 0.032	0.673TyrGln: 0.673 ± 0.03	2.025TyrArg: 2.025 ± 0.051	1.33TyrSer: 1.33 ± 0.041	1.065TyrThr: 1.065 ± 0.034	1.526TyrVal: 1.526 ± 0.041	0.385TyrTrp: 0.385 ± 0.021	0.649TyrTyr: 0.649 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2877 proteins (903915 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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