Amino acid dipepetide frequency for Bacillus taeanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.003AlaAla: 7.003 ± 0.095	0.63AlaCys: 0.63 ± 0.022	3.159AlaAsp: 3.159 ± 0.055	4.854AlaGlu: 4.854 ± 0.069	3.398AlaPhe: 3.398 ± 0.055	5.17AlaGly: 5.17 ± 0.075	1.316AlaHis: 1.316 ± 0.034	5.239AlaIle: 5.239 ± 0.075	4.702AlaLys: 4.702 ± 0.065	7.498AlaLeu: 7.498 ± 0.084	1.922AlaMet: 1.922 ± 0.036	2.795AlaAsn: 2.795 ± 0.047	2.085AlaPro: 2.085 ± 0.044	2.181AlaGln: 2.181 ± 0.045	2.412AlaArg: 2.412 ± 0.051	4.037AlaSer: 4.037 ± 0.055	2.54AlaThr: 2.54 ± 0.054	6.33AlaVal: 6.33 ± 0.071	0.594AlaTrp: 0.594 ± 0.023	2.329AlaTyr: 2.329 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.478CysAla: 0.478 ± 0.02	0.122CysCys: 0.122 ± 0.011	0.383CysAsp: 0.383 ± 0.017	0.516CysGlu: 0.516 ± 0.025	0.376CysPhe: 0.376 ± 0.02	0.716CysGly: 0.716 ± 0.025	0.225CysHis: 0.225 ± 0.014	0.495CysIle: 0.495 ± 0.019	0.413CysLys: 0.413 ± 0.017	0.711CysLeu: 0.711 ± 0.027	0.186CysMet: 0.186 ± 0.013	0.313CysAsn: 0.313 ± 0.016	0.382CysPro: 0.382 ± 0.02	0.248CysGln: 0.248 ± 0.015	0.3CysArg: 0.3 ± 0.017	0.559CysSer: 0.559 ± 0.022	0.422CysThr: 0.422 ± 0.018	0.403CysVal: 0.403 ± 0.017	0.089CysTrp: 0.089 ± 0.008	0.288CysTyr: 0.288 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	2.911AspAla: 2.911 ± 0.054	0.395AspCys: 0.395 ± 0.018	2.105AspAsp: 2.105 ± 0.052	4.022AspGlu: 4.022 ± 0.06	2.198AspPhe: 2.198 ± 0.042	3.131AspGly: 3.131 ± 0.056	1.222AspHis: 1.222 ± 0.03	3.735AspIle: 3.735 ± 0.056	2.811AspLys: 2.811 ± 0.046	4.725AspLeu: 4.725 ± 0.066	1.201AspMet: 1.201 ± 0.033	1.658AspAsn: 1.658 ± 0.041	1.894AspPro: 1.894 ± 0.04	1.886AspGln: 1.886 ± 0.039	2.022AspArg: 2.022 ± 0.038	2.266AspSer: 2.266 ± 0.045	2.14AspThr: 2.14 ± 0.044	3.548AspVal: 3.548 ± 0.057	0.608AspTrp: 0.608 ± 0.024	2.109AspTyr: 2.109 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.828GluAla: 5.828 ± 0.078	0.415GluCys: 0.415 ± 0.018	3.568GluAsp: 3.568 ± 0.055	8.062GluGlu: 8.062 ± 0.107	2.543GluPhe: 2.543 ± 0.051	4.511GluGly: 4.511 ± 0.065	1.637GluHis: 1.637 ± 0.04	5.714GluIle: 5.714 ± 0.068	7.362GluLys: 7.362 ± 0.087	7.286GluLeu: 7.286 ± 0.094	2.319GluMet: 2.319 ± 0.044	4.133GluAsn: 4.133 ± 0.059	1.875GluPro: 1.875 ± 0.041	3.476GluGln: 3.476 ± 0.061	3.606GluArg: 3.606 ± 0.061	3.533GluSer: 3.533 ± 0.059	3.998GluThr: 3.998 ± 0.056	5.461GluVal: 5.461 ± 0.073	0.85GluTrp: 0.85 ± 0.027	2.149GluTyr: 2.149 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	2.993PheAla: 2.993 ± 0.057	0.376PheCys: 0.376 ± 0.017	2.142PheAsp: 2.142 ± 0.048	2.84PheGlu: 2.84 ± 0.041	2.467PhePhe: 2.467 ± 0.064	3.312PheGly: 3.312 ± 0.06	1.095PheHis: 1.095 ± 0.025	4.006PheIle: 4.006 ± 0.081	2.569PheLys: 2.569 ± 0.046	4.883PheLeu: 4.883 ± 0.079	1.138PheMet: 1.138 ± 0.033	2.014PheAsn: 2.014 ± 0.041	1.721PhePro: 1.721 ± 0.035	1.742PheGln: 1.742 ± 0.04	1.46PheArg: 1.46 ± 0.034	3.325PheSer: 3.325 ± 0.058	2.573PheThr: 2.573 ± 0.049	3.058PheVal: 3.058 ± 0.057	0.436PheTrp: 0.436 ± 0.021	1.844PheTyr: 1.844 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.947GlyAla: 4.947 ± 0.08	0.642GlyCys: 0.642 ± 0.02	3.021GlyAsp: 3.021 ± 0.052	4.749GlyGlu: 4.749 ± 0.067	3.478GlyPhe: 3.478 ± 0.063	4.795GlyGly: 4.795 ± 0.089	1.327GlyHis: 1.327 ± 0.037	6.12GlyIle: 6.12 ± 0.081	5.107GlyLys: 5.107 ± 0.064	6.581GlyLeu: 6.581 ± 0.078	2.11GlyMet: 2.11 ± 0.047	2.621GlyAsn: 2.621 ± 0.05	1.724GlyPro: 1.724 ± 0.045	2.047GlyGln: 2.047 ± 0.045	2.46GlyArg: 2.46 ± 0.046	3.922GlySer: 3.922 ± 0.064	3.858GlyThr: 3.858 ± 0.057	5.027GlyVal: 5.027 ± 0.07	0.842GlyTrp: 0.842 ± 0.029	2.741GlyTyr: 2.741 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.322HisAla: 1.322 ± 0.033	0.208HisCys: 0.208 ± 0.012	1.012HisAsp: 1.012 ± 0.032	1.515HisGlu: 1.515 ± 0.033	1.154HisPhe: 1.154 ± 0.035	1.426HisGly: 1.426 ± 0.032	0.791HisHis: 0.791 ± 0.03	1.618HisIle: 1.618 ± 0.037	1.166HisLys: 1.166 ± 0.032	2.333HisLeu: 2.333 ± 0.043	0.504HisMet: 0.504 ± 0.021	0.893HisAsn: 0.893 ± 0.023	1.161HisPro: 1.161 ± 0.03	0.851HisGln: 0.851 ± 0.029	0.88HisArg: 0.88 ± 0.028	1.283HisSer: 1.283 ± 0.032	1.131HisThr: 1.131 ± 0.027	1.407HisVal: 1.407 ± 0.035	0.24HisTrp: 0.24 ± 0.015	1.057HisTyr: 1.057 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.967IleAla: 5.967 ± 0.09	0.716IleCys: 0.716 ± 0.022	4.156IleAsp: 4.156 ± 0.06	6.185IleGlu: 6.185 ± 0.075	3.258IlePhe: 3.258 ± 0.066	6.279IleGly: 6.279 ± 0.088	1.693IleHis: 1.693 ± 0.039	5.824IleIle: 5.824 ± 0.078	4.722IleLys: 4.722 ± 0.065	7.009IleLeu: 7.009 ± 0.096	1.698IleMet: 1.698 ± 0.041	3.433IleAsn: 3.433 ± 0.052	3.381IlePro: 3.381 ± 0.055	2.817IleGln: 2.817 ± 0.049	2.921IleArg: 2.921 ± 0.053	5.092IleSer: 5.092 ± 0.063	4.309IleThr: 4.309 ± 0.05	5.64IleVal: 5.64 ± 0.078	0.654IleTrp: 0.654 ± 0.026	2.485IleTyr: 2.485 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	4.984LysAla: 4.984 ± 0.058	0.363LysCys: 0.363 ± 0.014	3.508LysAsp: 3.508 ± 0.052	7.869LysGlu: 7.869 ± 0.099	1.943LysPhe: 1.943 ± 0.042	4.533LysGly: 4.533 ± 0.06	1.521LysHis: 1.521 ± 0.04	4.848LysIle: 4.848 ± 0.068	6.46LysLys: 6.46 ± 0.08	5.949LysLeu: 5.949 ± 0.082	2.21LysMet: 2.21 ± 0.041	3.546LysAsn: 3.546 ± 0.052	2.281LysPro: 2.281 ± 0.045	3.415LysGln: 3.415 ± 0.057	3.504LysArg: 3.504 ± 0.058	3.525LysSer: 3.525 ± 0.05	3.737LysThr: 3.737 ± 0.052	4.924LysVal: 4.924 ± 0.066	0.871LysTrp: 0.871 ± 0.029	2.067LysTyr: 2.067 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	7.204LeuAla: 7.204 ± 0.078	0.688LeuCys: 0.688 ± 0.021	4.357LeuAsp: 4.357 ± 0.061	6.81LeuGlu: 6.81 ± 0.085	5.037LeuPhe: 5.037 ± 0.078	6.451LeuGly: 6.451 ± 0.084	2.076LeuHis: 2.076 ± 0.048	7.445LeuIle: 7.445 ± 0.089	7.064LeuLys: 7.064 ± 0.082	10.598LeuLeu: 10.598 ± 0.124	2.409LeuMet: 2.409 ± 0.049	4.523LeuAsn: 4.523 ± 0.059	3.932LeuPro: 3.932 ± 0.053	3.694LeuGln: 3.694 ± 0.063	3.384LeuArg: 3.384 ± 0.053	6.97LeuSer: 6.97 ± 0.085	5.763LeuThr: 5.763 ± 0.065	6.198LeuVal: 6.198 ± 0.072	0.842LeuTrp: 0.842 ± 0.028	3.258LeuTyr: 3.258 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	1.888MetAla: 1.888 ± 0.035	0.151MetCys: 0.151 ± 0.011	1.182MetAsp: 1.182 ± 0.031	1.823MetGlu: 1.823 ± 0.041	1.081MetPhe: 1.081 ± 0.032	1.694MetGly: 1.694 ± 0.041	0.437MetHis: 0.437 ± 0.018	2.433MetIle: 2.433 ± 0.047	2.539MetLys: 2.539 ± 0.047	2.577MetLeu: 2.577 ± 0.05	0.945MetMet: 0.945 ± 0.031	1.585MetAsn: 1.585 ± 0.034	1.046MetPro: 1.046 ± 0.031	0.838MetGln: 0.838 ± 0.023	1.006MetArg: 1.006 ± 0.032	1.566MetSer: 1.566 ± 0.037	1.635MetThr: 1.635 ± 0.034	1.757MetVal: 1.757 ± 0.034	0.192MetTrp: 0.192 ± 0.012	0.734MetTyr: 0.734 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	2.737AsnAla: 2.737 ± 0.049	0.353AsnCys: 0.353 ± 0.017	2.292AsnAsp: 2.292 ± 0.045	3.947AsnGlu: 3.947 ± 0.054	1.69AsnPhe: 1.69 ± 0.037	3.282AsnGly: 3.282 ± 0.057	1.11AsnHis: 1.11 ± 0.03	3.584AsnIle: 3.584 ± 0.059	3.244AsnLys: 3.244 ± 0.05	3.905AsnLeu: 3.905 ± 0.052	1.261AsnMet: 1.261 ± 0.032	2.247AsnAsn: 2.247 ± 0.046	2.161AsnPro: 2.161 ± 0.047	1.901AsnGln: 1.901 ± 0.044	2.033AsnArg: 2.033 ± 0.042	2.327AsnSer: 2.327 ± 0.042	2.179AsnThr: 2.179 ± 0.046	3.084AsnVal: 3.084 ± 0.051	0.561AsnTrp: 0.561 ± 0.018	1.714AsnTyr: 1.714 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	2.226ProAla: 2.226 ± 0.046	0.255ProCys: 0.255 ± 0.015	1.796ProAsp: 1.796 ± 0.045	2.911ProGlu: 2.911 ± 0.047	2.013ProPhe: 2.013 ± 0.04	2.238ProGly: 2.238 ± 0.042	0.899ProHis: 0.899 ± 0.028	2.829ProIle: 2.829 ± 0.049	2.266ProLys: 2.266 ± 0.042	3.754ProLeu: 3.754 ± 0.06	0.84ProMet: 0.84 ± 0.024	1.828ProAsn: 1.828 ± 0.04	0.981ProPro: 0.981 ± 0.03	1.042ProGln: 1.042 ± 0.031	1.106ProArg: 1.106 ± 0.031	2.274ProSer: 2.274 ± 0.048	2.01ProThr: 2.01 ± 0.039	2.735ProVal: 2.735 ± 0.048	0.396ProTrp: 0.396 ± 0.018	1.45ProTyr: 1.45 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.585GlnAla: 2.585 ± 0.045	0.234GlnCys: 0.234 ± 0.014	1.488GlnAsp: 1.488 ± 0.036	2.957GlnGlu: 2.957 ± 0.051	1.679GlnPhe: 1.679 ± 0.035	2.153GlnGly: 2.153 ± 0.045	0.838GlnHis: 0.838 ± 0.027	2.48GlnIle: 2.48 ± 0.044	2.978GlnLys: 2.978 ± 0.058	3.927GlnLeu: 3.927 ± 0.064	1.036GlnMet: 1.036 ± 0.031	1.714GlnAsn: 1.714 ± 0.039	1.233GlnPro: 1.233 ± 0.028	1.816GlnGln: 1.816 ± 0.053	1.403GlnArg: 1.403 ± 0.034	2.232GlnSer: 2.232 ± 0.047	2.09GlnThr: 2.09 ± 0.042	2.191GlnVal: 2.191 ± 0.045	0.423GlnTrp: 0.423 ± 0.02	1.38GlnTyr: 1.38 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	2.326ArgAla: 2.326 ± 0.048	0.258ArgCys: 0.258 ± 0.015	1.837ArgAsp: 1.837 ± 0.039	3.103ArgGlu: 3.103 ± 0.049	1.941ArgPhe: 1.941 ± 0.041	2.235ArgGly: 2.235 ± 0.041	0.758ArgHis: 0.758 ± 0.025	2.974ArgIle: 2.974 ± 0.05	3.189ArgLys: 3.189 ± 0.053	3.833ArgLeu: 3.833 ± 0.065	1.145ArgMet: 1.145 ± 0.027	1.906ArgAsn: 1.906 ± 0.044	1.286ArgPro: 1.286 ± 0.032	1.406ArgGln: 1.406 ± 0.032	1.713ArgArg: 1.713 ± 0.041	2.224ArgSer: 2.224 ± 0.042	1.989ArgThr: 1.989 ± 0.045	2.437ArgVal: 2.437 ± 0.049	0.404ArgTrp: 0.404 ± 0.019	1.644ArgTyr: 1.644 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.801SerAla: 3.801 ± 0.053	0.446SerCys: 0.446 ± 0.019	2.624SerAsp: 2.624 ± 0.052	4.109SerGlu: 4.109 ± 0.061	3.467SerPhe: 3.467 ± 0.064	4.28SerGly: 4.28 ± 0.066	1.331SerHis: 1.331 ± 0.036	4.983SerIle: 4.983 ± 0.064	3.865SerLys: 3.865 ± 0.053	6.269SerLeu: 6.269 ± 0.086	1.691SerMet: 1.691 ± 0.037	2.485SerAsn: 2.485 ± 0.048	2.145SerPro: 2.145 ± 0.041	1.879SerGln: 1.879 ± 0.039	2.111SerArg: 2.111 ± 0.043	4.013SerSer: 4.013 ± 0.063	3.0SerThr: 3.0 ± 0.05	4.008SerVal: 4.008 ± 0.06	0.671SerTrp: 0.671 ± 0.023	2.319SerTyr: 2.319 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	4.176ThrAla: 4.176 ± 0.058	0.389ThrCys: 0.389 ± 0.018	2.305ThrAsp: 2.305 ± 0.044	3.437ThrGlu: 3.437 ± 0.057	2.652ThrPhe: 2.652 ± 0.048	3.933ThrGly: 3.933 ± 0.056	1.013ThrHis: 1.013 ± 0.031	4.617ThrIle: 4.617 ± 0.067	3.429ThrLys: 3.429 ± 0.056	5.216ThrLeu: 5.216 ± 0.059	1.35ThrMet: 1.35 ± 0.035	2.404ThrAsn: 2.404 ± 0.045	2.187ThrPro: 2.187 ± 0.044	1.252ThrGln: 1.252 ± 0.035	1.745ThrArg: 1.745 ± 0.035	3.066ThrSer: 3.066 ± 0.053	2.697ThrThr: 2.697 ± 0.049	4.074ThrVal: 4.074 ± 0.057	0.52ThrTrp: 0.52 ± 0.019	1.914ThrTyr: 1.914 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	4.185ValAla: 4.185 ± 0.063	0.591ValCys: 0.591 ± 0.024	3.322ValAsp: 3.322 ± 0.054	5.092ValGlu: 5.092 ± 0.065	3.239ValPhe: 3.239 ± 0.053	4.702ValGly: 4.702 ± 0.073	1.434ValHis: 1.434 ± 0.034	5.997ValIle: 5.997 ± 0.078	5.045ValLys: 5.045 ± 0.064	7.078ValLeu: 7.078 ± 0.085	1.919ValMet: 1.919 ± 0.037	3.324ValAsn: 3.324 ± 0.055	2.665ValPro: 2.665 ± 0.045	2.395ValGln: 2.395 ± 0.037	2.547ValArg: 2.547 ± 0.048	4.604ValSer: 4.604 ± 0.06	4.043ValThr: 4.043 ± 0.062	5.014ValVal: 5.014 ± 0.068	0.661ValTrp: 0.661 ± 0.024	2.339ValTyr: 2.339 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.603TrpAla: 0.603 ± 0.026	0.081TrpCys: 0.081 ± 0.008	0.509TrpAsp: 0.509 ± 0.021	0.712TrpGlu: 0.712 ± 0.023	0.54TrpPhe: 0.54 ± 0.021	0.682TrpGly: 0.682 ± 0.023	0.235TrpHis: 0.235 ± 0.013	0.874TrpIle: 0.874 ± 0.027	0.793TrpLys: 0.793 ± 0.025	1.147TrpLeu: 1.147 ± 0.033	0.336TrpMet: 0.336 ± 0.018	0.576TrpAsn: 0.576 ± 0.024	0.273TrpPro: 0.273 ± 0.014	0.419TrpGln: 0.419 ± 0.018	0.397TrpArg: 0.397 ± 0.02	0.609TrpSer: 0.609 ± 0.023	0.494TrpThr: 0.494 ± 0.019	0.648TrpVal: 0.648 ± 0.026	0.153TrpTrp: 0.153 ± 0.013	0.337TrpTyr: 0.337 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.028TyrAla: 2.028 ± 0.044	0.312TyrCys: 0.312 ± 0.016	1.826TyrAsp: 1.826 ± 0.037	2.813TyrGlu: 2.813 ± 0.056	1.839TyrPhe: 1.839 ± 0.045	2.599TyrGly: 2.599 ± 0.053	0.992TyrHis: 0.992 ± 0.029	2.425TyrIle: 2.425 ± 0.049	2.334TyrLys: 2.334 ± 0.05	3.426TyrLeu: 3.426 ± 0.048	0.887TyrMet: 0.887 ± 0.026	1.614TyrAsn: 1.614 ± 0.039	1.436TyrPro: 1.436 ± 0.036	1.531TyrGln: 1.531 ± 0.037	1.598TyrArg: 1.598 ± 0.036	2.07TyrSer: 2.07 ± 0.04	1.768TyrThr: 1.768 ± 0.039	2.249TyrVal: 2.249 ± 0.046	0.413TyrTrp: 0.413 ± 0.019	1.539TyrTyr: 1.539 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4392 proteins (1266379 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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