Bovine viral diarrhea virus (isolate NADL) (BVDV) (Mucosal disease virus)

Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Flasuviricetes; Amarillovirales; Flaviviridae; Pestivirus; Pestivirus A

Average proteome isoelectric point is 7.61

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

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Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|P19711|POLG_BVDVN Genome polyprotein OS=Bovine viral diarrhea virus (isolate NADL) OX=11100 PE=1 SV=2
MM1 pKa = 7.41EE2 pKa = 6.74LITNEE7 pKa = 4.62LLYY10 pKa = 9.4KK11 pKa = 9.83TYY13 pKa = 9.89KK14 pKa = 9.11QKK16 pKa = 10.7PVGVEE21 pKa = 3.81EE22 pKa = 4.22PVYY25 pKa = 10.8DD26 pKa = 4.0QAGDD30 pKa = 3.63PLFGEE35 pKa = 5.1RR36 pKa = 11.84GAVHH40 pKa = 6.19PQSTLKK46 pKa = 10.68LPHH49 pKa = 6.51KK50 pKa = 10.18RR51 pKa = 11.84GEE53 pKa = 4.03RR54 pKa = 11.84DD55 pKa = 3.18VPTNLASLPKK65 pKa = 10.43RR66 pKa = 11.84GDD68 pKa = 3.51CRR70 pKa = 11.84SGNSRR75 pKa = 11.84GPVSGIYY82 pKa = 10.08LKK84 pKa = 10.52PGPLFYY90 pKa = 10.26QDD92 pKa = 3.33YY93 pKa = 9.91KK94 pKa = 11.05GPVYY98 pKa = 10.46HH99 pKa = 7.33RR100 pKa = 11.84APLEE104 pKa = 3.95LFEE107 pKa = 4.98EE108 pKa = 5.6GSMCEE113 pKa = 3.74TTKK116 pKa = 10.73RR117 pKa = 11.84IGRR120 pKa = 11.84VTGSDD125 pKa = 2.65GKK127 pKa = 10.74LYY129 pKa = 10.41HH130 pKa = 7.02IYY132 pKa = 10.63VCIDD136 pKa = 2.83GCIIIKK142 pKa = 10.14SATRR146 pKa = 11.84SYY148 pKa = 10.87QRR150 pKa = 11.84VFRR153 pKa = 11.84WVHH156 pKa = 5.25NRR158 pKa = 11.84LDD160 pKa = 3.76CPLWVTTCSDD170 pKa = 3.5TKK172 pKa = 11.27EE173 pKa = 3.75EE174 pKa = 4.27GATKK178 pKa = 10.54KK179 pKa = 8.99KK180 pKa = 6.95TQKK183 pKa = 9.8PDD185 pKa = 2.97RR186 pKa = 11.84LEE188 pKa = 4.04RR189 pKa = 11.84GKK191 pKa = 10.2MKK193 pKa = 10.29IVPKK197 pKa = 10.38EE198 pKa = 3.93SEE200 pKa = 4.35KK201 pKa = 11.0DD202 pKa = 3.72SKK204 pKa = 9.91TKK206 pKa = 10.63PPDD209 pKa = 3.05ATIVVEE215 pKa = 4.27GVKK218 pKa = 10.48YY219 pKa = 8.33QVRR222 pKa = 11.84KK223 pKa = 9.75KK224 pKa = 11.07GKK226 pKa = 7.62TKK228 pKa = 10.72SKK230 pKa = 8.85NTQDD234 pKa = 3.54GLYY237 pKa = 10.13HH238 pKa = 6.52NKK240 pKa = 9.96NKK242 pKa = 9.57PQEE245 pKa = 4.14SRR247 pKa = 11.84KK248 pKa = 9.96KK249 pKa = 10.59LEE251 pKa = 3.96KK252 pKa = 10.65ALLAWAIIAIVLFQVTMGEE271 pKa = 6.12NITQWNLQDD280 pKa = 4.15NGTEE284 pKa = 4.93GIQRR288 pKa = 11.84AMFQRR293 pKa = 11.84GVNRR297 pKa = 11.84SLHH300 pKa = 6.13GIWPEE305 pKa = 4.1KK306 pKa = 10.07ICTGVPSHH314 pKa = 7.06LATDD318 pKa = 4.03IEE320 pKa = 4.73LKK322 pKa = 9.73TIHH325 pKa = 6.61GMMDD329 pKa = 2.99ASEE332 pKa = 4.21KK333 pKa = 10.28TNYY336 pKa = 7.46TCCRR340 pKa = 11.84LQRR343 pKa = 11.84HH344 pKa = 5.77EE345 pKa = 4.26WNKK348 pKa = 10.67HH349 pKa = 4.0GWCNWYY355 pKa = 10.51NIEE358 pKa = 4.09PWILVMNRR366 pKa = 11.84TQANLTEE373 pKa = 4.42GQPPRR378 pKa = 11.84EE379 pKa = 4.2CAVTCRR385 pKa = 11.84YY386 pKa = 10.25DD387 pKa = 3.27RR388 pKa = 11.84ASDD391 pKa = 3.98LNVVTQARR399 pKa = 11.84DD400 pKa = 3.24SPTPLTGCKK409 pKa = 9.63KK410 pKa = 10.51GKK412 pKa = 9.45NFSFAGILMRR422 pKa = 11.84GPCNFEE428 pKa = 3.5IAASDD433 pKa = 3.74VLFKK437 pKa = 10.38EE438 pKa = 4.47HH439 pKa = 6.15EE440 pKa = 4.83RR441 pKa = 11.84ISMFQDD447 pKa = 2.91TTLYY451 pKa = 11.0LVDD454 pKa = 4.22GLTNSLEE461 pKa = 4.33GARR464 pKa = 11.84QGTAKK469 pKa = 9.65LTTWLGKK476 pKa = 9.55QLGILGKK483 pKa = 10.58KK484 pKa = 9.99LEE486 pKa = 4.64NKK488 pKa = 9.86SKK490 pKa = 8.64TWFGAYY496 pKa = 9.21AASPYY501 pKa = 10.34CDD503 pKa = 3.41VDD505 pKa = 4.19RR506 pKa = 11.84KK507 pKa = 10.22IGYY510 pKa = 8.08IWYY513 pKa = 7.53TKK515 pKa = 10.63NCTPACLPKK524 pKa = 9.26NTKK527 pKa = 9.59IVGPGKK533 pKa = 10.44FGTNAEE539 pKa = 4.3DD540 pKa = 3.83GKK542 pKa = 10.63ILHH545 pKa = 6.58EE546 pKa = 4.44MGGHH550 pKa = 6.07LSEE553 pKa = 4.56VLLLSLVVLSDD564 pKa = 3.92FAPEE568 pKa = 4.12TASVMYY574 pKa = 10.33LILHH578 pKa = 6.01FSIPQSHH585 pKa = 6.48VDD587 pKa = 5.17VMDD590 pKa = 4.6CDD592 pKa = 3.72KK593 pKa = 10.79TQLNLTVEE601 pKa = 4.5LTTAEE606 pKa = 4.42VIPGSVWNLGKK617 pKa = 10.13YY618 pKa = 9.24VCIRR622 pKa = 11.84PNWWPYY628 pKa = 7.13EE629 pKa = 4.26TTVVLAFEE637 pKa = 4.61EE638 pKa = 4.81VSQVVKK644 pKa = 10.68LVLRR648 pKa = 11.84ALRR651 pKa = 11.84DD652 pKa = 3.38LTRR655 pKa = 11.84IWNAATTTAFLVCLVKK671 pKa = 10.38IVRR674 pKa = 11.84GQMVQGILWLLLITGVQGHH693 pKa = 7.11LDD695 pKa = 3.8CKK697 pKa = 10.81PEE699 pKa = 3.85FSYY702 pKa = 11.22AIAKK706 pKa = 9.68DD707 pKa = 3.59EE708 pKa = 5.35RR709 pKa = 11.84IGQLGAEE716 pKa = 4.57GLTTTWKK723 pKa = 10.29EE724 pKa = 3.76YY725 pKa = 10.45SPGMKK730 pKa = 10.27LEE732 pKa = 4.12DD733 pKa = 3.32TMVIAWCEE741 pKa = 3.97DD742 pKa = 2.9GKK744 pKa = 11.61LMYY747 pKa = 10.26LQRR750 pKa = 11.84CTRR753 pKa = 11.84EE754 pKa = 3.7TRR756 pKa = 11.84YY757 pKa = 10.0LAILHH762 pKa = 5.65TRR764 pKa = 11.84ALPTSVVFKK773 pKa = 10.91KK774 pKa = 10.85LFDD777 pKa = 3.52GRR779 pKa = 11.84KK780 pKa = 8.57QEE782 pKa = 5.49DD783 pKa = 3.99VVEE786 pKa = 4.23MNDD789 pKa = 3.13NFEE792 pKa = 5.69FGLCPCDD799 pKa = 3.09AKK801 pKa = 10.98PIVRR805 pKa = 11.84GKK807 pKa = 11.06FNTTLLNGPAFQMVCPIGWTGTVSCTSFNMDD838 pKa = 3.25TLATTVVRR846 pKa = 11.84TYY848 pKa = 10.73RR849 pKa = 11.84RR850 pKa = 11.84SKK852 pKa = 10.26PFPHH856 pKa = 6.63RR857 pKa = 11.84QGCITQKK864 pKa = 11.02NLGEE868 pKa = 4.55DD869 pKa = 3.51LHH871 pKa = 8.05NCILGGNWTCVPGDD885 pKa = 3.36QLLYY889 pKa = 10.49KK890 pKa = 10.21GGSIEE895 pKa = 4.07SCKK898 pKa = 8.95WCGYY902 pKa = 6.98QFKK905 pKa = 10.12EE906 pKa = 4.79SEE908 pKa = 4.48GLPHH912 pKa = 6.82YY913 pKa = 10.14PIGKK917 pKa = 9.32CKK919 pKa = 10.69LEE921 pKa = 4.12NEE923 pKa = 4.05TGYY926 pKa = 11.28RR927 pKa = 11.84LVDD930 pKa = 3.34STSCNRR936 pKa = 11.84EE937 pKa = 3.24GVAIVPQGTLKK948 pKa = 10.89CKK950 pKa = 9.98IGKK953 pKa = 6.63TTVQVIAMDD962 pKa = 4.04TKK964 pKa = 10.6LGPMPCRR971 pKa = 11.84PYY973 pKa = 10.71EE974 pKa = 4.51IISSEE979 pKa = 4.29GPVEE983 pKa = 4.0KK984 pKa = 9.47TACTFNYY991 pKa = 8.82TKK993 pKa = 9.86TLKK996 pKa = 10.55NKK998 pKa = 9.56YY999 pKa = 9.45FEE1001 pKa = 4.9PRR1003 pKa = 11.84DD1004 pKa = 3.8SYY1006 pKa = 10.55FQQYY1010 pKa = 7.2MLKK1013 pKa = 10.68GEE1015 pKa = 3.98YY1016 pKa = 9.97QYY1018 pKa = 11.36WFDD1021 pKa = 5.68LEE1023 pKa = 4.6VTDD1026 pKa = 4.22HH1027 pKa = 6.42HH1028 pKa = 7.2RR1029 pKa = 11.84DD1030 pKa = 3.46YY1031 pKa = 10.69FAEE1034 pKa = 4.69SILVVVVALLGGRR1047 pKa = 11.84YY1048 pKa = 8.74VLWLLVTYY1056 pKa = 9.29MVLSEE1061 pKa = 4.04QKK1063 pKa = 10.97ALGIQYY1069 pKa = 10.82GSGEE1073 pKa = 4.26VVMMGNLLTHH1083 pKa = 6.35NNIEE1087 pKa = 4.21VVTYY1091 pKa = 9.57FLLLYY1096 pKa = 10.57LLLRR1100 pKa = 11.84EE1101 pKa = 4.2EE1102 pKa = 4.7SVKK1105 pKa = 10.59KK1106 pKa = 9.55WVLLLYY1112 pKa = 10.15HH1113 pKa = 7.0ILVVHH1118 pKa = 6.85PIKK1121 pKa = 10.8SVIVILLMIGDD1132 pKa = 4.1VVKK1135 pKa = 10.82ADD1137 pKa = 3.68SGGQEE1142 pKa = 4.0YY1143 pKa = 10.58LGKK1146 pKa = 9.81IDD1148 pKa = 4.33LCFTTVVLIVIGLIIARR1165 pKa = 11.84RR1166 pKa = 11.84DD1167 pKa = 3.49PTIVPLVTIMAALRR1181 pKa = 11.84VTEE1184 pKa = 4.5LTHH1187 pKa = 6.74QPGVDD1192 pKa = 2.75IAVAVMTITLLMVSYY1207 pKa = 9.15VTDD1210 pKa = 3.18YY1211 pKa = 11.0FRR1213 pKa = 11.84YY1214 pKa = 9.9KK1215 pKa = 10.42KK1216 pKa = 9.28WLQCILSLVSAVFLIRR1232 pKa = 11.84SLIYY1236 pKa = 10.11LGRR1239 pKa = 11.84IEE1241 pKa = 4.44MPEE1244 pKa = 3.57VTIPNWRR1251 pKa = 11.84PLTLILLYY1259 pKa = 10.63LISTTIVTRR1268 pKa = 11.84WKK1270 pKa = 10.58VDD1272 pKa = 3.25VAGLLLQCVPILLLVTTLWADD1293 pKa = 4.13FLTLILILPTYY1304 pKa = 9.99EE1305 pKa = 4.28LVKK1308 pKa = 10.49LYY1310 pKa = 10.36YY1311 pKa = 10.39LKK1313 pKa = 9.76TVRR1316 pKa = 11.84TDD1318 pKa = 3.47TEE1320 pKa = 4.34RR1321 pKa = 11.84SWLGGIDD1328 pKa = 3.63YY1329 pKa = 9.36TRR1331 pKa = 11.84VDD1333 pKa = 3.57SIYY1336 pKa = 11.05DD1337 pKa = 3.29VDD1339 pKa = 3.74EE1340 pKa = 4.92SGEE1343 pKa = 4.23GVYY1346 pKa = 10.49LFPSRR1351 pKa = 11.84QKK1353 pKa = 10.59AQGNFSILLPLIKK1366 pKa = 9.73ATLISCVSSKK1376 pKa = 9.44WQLIYY1381 pKa = 10.31MSYY1384 pKa = 9.29LTLDD1388 pKa = 3.58FMYY1391 pKa = 10.85YY1392 pKa = 6.66MHH1394 pKa = 7.33RR1395 pKa = 11.84KK1396 pKa = 9.12VIEE1399 pKa = 4.64EE1400 pKa = 3.8ISGGTNIISRR1410 pKa = 11.84LVAALIEE1417 pKa = 4.96LNWSMEE1423 pKa = 4.07EE1424 pKa = 4.11EE1425 pKa = 4.06EE1426 pKa = 4.97SKK1428 pKa = 11.04GLKK1431 pKa = 9.87KK1432 pKa = 10.57FYY1434 pKa = 10.51LLSGRR1439 pKa = 11.84LRR1441 pKa = 11.84NLIIKK1446 pKa = 9.67HH1447 pKa = 4.95KK1448 pKa = 10.31VRR1450 pKa = 11.84NEE1452 pKa = 4.18TVASWYY1458 pKa = 10.77GEE1460 pKa = 3.99EE1461 pKa = 4.41EE1462 pKa = 4.82VYY1464 pKa = 11.12GMPKK1468 pKa = 9.84IMTIIKK1474 pKa = 10.35ASTLSKK1480 pKa = 10.45SRR1482 pKa = 11.84HH1483 pKa = 5.93CIICTVCEE1491 pKa = 3.82GRR1493 pKa = 11.84EE1494 pKa = 4.29WKK1496 pKa = 10.8GGTCPKK1502 pKa = 9.94CGRR1505 pKa = 11.84HH1506 pKa = 5.56GKK1508 pKa = 9.47PITCGMSLADD1518 pKa = 4.02FEE1520 pKa = 4.36EE1521 pKa = 4.17RR1522 pKa = 11.84HH1523 pKa = 5.64YY1524 pKa = 11.36KK1525 pKa = 10.34RR1526 pKa = 11.84IFIRR1530 pKa = 11.84EE1531 pKa = 4.08GNFEE1535 pKa = 4.33GMCSRR1540 pKa = 11.84CQGKK1544 pKa = 8.5HH1545 pKa = 4.94RR1546 pKa = 11.84RR1547 pKa = 11.84FEE1549 pKa = 3.89MDD1551 pKa = 3.94RR1552 pKa = 11.84EE1553 pKa = 4.32PKK1555 pKa = 9.15SARR1558 pKa = 11.84YY1559 pKa = 8.76CAEE1562 pKa = 4.06CNRR1565 pKa = 11.84LHH1567 pKa = 6.65PAEE1570 pKa = 5.35EE1571 pKa = 4.25GDD1573 pKa = 3.94FWAEE1577 pKa = 3.63SSMLGLKK1584 pKa = 8.2ITYY1587 pKa = 8.35FALMDD1592 pKa = 3.85GKK1594 pKa = 11.16VYY1596 pKa = 10.65DD1597 pKa = 3.45ITEE1600 pKa = 3.88WAGCQRR1606 pKa = 11.84VGISPDD1612 pKa = 3.07THH1614 pKa = 6.82RR1615 pKa = 11.84VPCHH1619 pKa = 5.71ISFGSRR1625 pKa = 11.84MPFRR1629 pKa = 11.84QEE1631 pKa = 3.44YY1632 pKa = 10.32NGFVQYY1638 pKa = 7.76TARR1641 pKa = 11.84GQLFLRR1647 pKa = 11.84NLPVLATKK1655 pKa = 10.78VKK1657 pKa = 9.45MLMVGNLGEE1666 pKa = 4.38EE1667 pKa = 4.2IGNLEE1672 pKa = 3.89HH1673 pKa = 7.03LGWILRR1679 pKa = 11.84GPAVCKK1685 pKa = 10.48KK1686 pKa = 8.65ITEE1689 pKa = 4.21HH1690 pKa = 6.35EE1691 pKa = 4.25KK1692 pKa = 10.34CHH1694 pKa = 7.42INILDD1699 pKa = 3.77KK1700 pKa = 10.62LTAFFGIMPRR1710 pKa = 11.84GTTPRR1715 pKa = 11.84APVRR1719 pKa = 11.84FPTSLLKK1726 pKa = 10.4VRR1728 pKa = 11.84RR1729 pKa = 11.84GLEE1732 pKa = 3.9TAWAYY1737 pKa = 6.64THH1739 pKa = 6.28QGGISSVDD1747 pKa = 3.13HH1748 pKa = 5.0VTAGKK1753 pKa = 10.16DD1754 pKa = 3.45LLVCDD1759 pKa = 3.45SMGRR1763 pKa = 11.84TRR1765 pKa = 11.84VVCQSNNRR1773 pKa = 11.84LTDD1776 pKa = 3.32EE1777 pKa = 4.26TEE1779 pKa = 4.22YY1780 pKa = 11.29GVKK1783 pKa = 9.44TDD1785 pKa = 3.77SGCPDD1790 pKa = 3.59GARR1793 pKa = 11.84CYY1795 pKa = 10.55VLNPEE1800 pKa = 4.53AVNISGSKK1808 pKa = 9.47GAVVHH1813 pKa = 5.68LQKK1816 pKa = 9.97TGGEE1820 pKa = 4.5FTCVTASGTPAFFDD1834 pKa = 4.19LKK1836 pKa = 10.87NLKK1839 pKa = 9.3GWSGLPIFEE1848 pKa = 4.7ASSGRR1853 pKa = 11.84VVGRR1857 pKa = 11.84VKK1859 pKa = 10.55VGKK1862 pKa = 9.99NEE1864 pKa = 3.77EE1865 pKa = 4.22SKK1867 pKa = 9.14PTKK1870 pKa = 10.02IMSGIQTVSKK1880 pKa = 10.79NRR1882 pKa = 11.84ADD1884 pKa = 3.46LTEE1887 pKa = 4.11MVKK1890 pKa = 10.53KK1891 pKa = 8.4ITSMNRR1897 pKa = 11.84GDD1899 pKa = 4.11FKK1901 pKa = 11.2QITLATGAGKK1911 pKa = 7.33TTEE1914 pKa = 4.17LPKK1917 pKa = 10.84AVIEE1921 pKa = 4.36EE1922 pKa = 4.12IGRR1925 pKa = 11.84HH1926 pKa = 4.72KK1927 pKa = 10.47RR1928 pKa = 11.84VLVLIPLRR1936 pKa = 11.84AAAEE1940 pKa = 4.05SVYY1943 pKa = 10.7QYY1945 pKa = 10.44MRR1947 pKa = 11.84LKK1949 pKa = 10.55HH1950 pKa = 5.79PSISFNLRR1958 pKa = 11.84IGDD1961 pKa = 3.78MKK1963 pKa = 10.67EE1964 pKa = 3.53GDD1966 pKa = 3.78MATGITYY1973 pKa = 10.43ASYY1976 pKa = 10.71GYY1978 pKa = 9.22FCQMPQPKK1986 pKa = 9.4LRR1988 pKa = 11.84AAMVEE1993 pKa = 3.71YY1994 pKa = 10.51SYY1996 pKa = 11.48IFLDD2000 pKa = 4.62EE2001 pKa = 4.17YY2002 pKa = 11.34HH2003 pKa = 7.01CATPEE2008 pKa = 3.58QLAIIGKK2015 pKa = 6.99IHH2017 pKa = 6.95RR2018 pKa = 11.84FSEE2021 pKa = 4.56SIRR2024 pKa = 11.84VVAMTATPAGSVTTTGQKK2042 pKa = 10.29HH2043 pKa = 6.11PIEE2046 pKa = 4.35EE2047 pKa = 4.85FIAPEE2052 pKa = 4.02VMKK2055 pKa = 11.22GEE2057 pKa = 4.31DD2058 pKa = 4.0LGSQFLDD2065 pKa = 2.94IAGLKK2070 pKa = 10.17IPVDD2074 pKa = 3.64EE2075 pKa = 4.83MKK2077 pKa = 11.25GNMLVFVPTRR2087 pKa = 11.84NMAVEE2092 pKa = 4.11VAKK2095 pKa = 10.61KK2096 pKa = 10.32LKK2098 pKa = 10.7AKK2100 pKa = 10.02GYY2102 pKa = 9.43NSGYY2106 pKa = 9.53YY2107 pKa = 9.94YY2108 pKa = 10.81SGEE2111 pKa = 4.04DD2112 pKa = 3.5PANLRR2117 pKa = 11.84VVTSQSPYY2125 pKa = 10.84VIVATNAIEE2134 pKa = 4.44SGVTLPDD2141 pKa = 4.12LDD2143 pKa = 4.14TVIDD2147 pKa = 3.75TGLKK2151 pKa = 8.46CEE2153 pKa = 3.79KK2154 pKa = 9.92RR2155 pKa = 11.84VRR2157 pKa = 11.84VSSKK2161 pKa = 10.1IPFIVTGLKK2170 pKa = 10.35RR2171 pKa = 11.84MAVTVGEE2178 pKa = 4.11QAQRR2182 pKa = 11.84RR2183 pKa = 11.84GRR2185 pKa = 11.84VGRR2188 pKa = 11.84VKK2190 pKa = 10.24PGRR2193 pKa = 11.84YY2194 pKa = 8.98YY2195 pKa = 10.84RR2196 pKa = 11.84SQEE2199 pKa = 3.93TATGSKK2205 pKa = 10.16DD2206 pKa = 3.27YY2207 pKa = 10.94HH2208 pKa = 6.9YY2209 pKa = 11.34DD2210 pKa = 3.2LLQAQRR2216 pKa = 11.84YY2217 pKa = 8.49GIEE2220 pKa = 4.21DD2221 pKa = 4.92GINVTKK2227 pKa = 10.54SFRR2230 pKa = 11.84EE2231 pKa = 3.95MNYY2234 pKa = 10.12DD2235 pKa = 2.79WSLYY2239 pKa = 10.66EE2240 pKa = 4.56EE2241 pKa = 5.14DD2242 pKa = 4.9SLLITQLEE2250 pKa = 4.21ILNNLLISEE2259 pKa = 4.96DD2260 pKa = 3.34LPAAVKK2266 pKa = 10.78NIMARR2271 pKa = 11.84TDD2273 pKa = 3.38HH2274 pKa = 7.2PEE2276 pKa = 4.72PIQLAYY2282 pKa = 10.72NSYY2285 pKa = 8.86EE2286 pKa = 3.89VQVPVLFPKK2295 pKa = 10.05IRR2297 pKa = 11.84NGEE2300 pKa = 4.05VTDD2303 pKa = 3.69TYY2305 pKa = 11.55EE2306 pKa = 4.41NYY2308 pKa = 10.84SFLNARR2314 pKa = 11.84KK2315 pKa = 9.63LGEE2318 pKa = 4.39DD2319 pKa = 3.56VPVYY2323 pKa = 10.17IYY2325 pKa = 10.16ATEE2328 pKa = 4.6DD2329 pKa = 3.09EE2330 pKa = 4.93DD2331 pKa = 5.36LAVDD2335 pKa = 5.31LLGLDD2340 pKa = 3.5WPDD2343 pKa = 4.02PGNQQVVEE2351 pKa = 4.14TGKK2354 pKa = 10.61ALKK2357 pKa = 10.14QVTGLSSAEE2366 pKa = 3.96NALLVALFGYY2376 pKa = 9.85VGYY2379 pKa = 10.05QALSKK2384 pKa = 10.33RR2385 pKa = 11.84HH2386 pKa = 5.26VPMITDD2392 pKa = 3.73IYY2394 pKa = 9.59TIEE2397 pKa = 4.16DD2398 pKa = 3.24QRR2400 pKa = 11.84LEE2402 pKa = 4.35DD2403 pKa = 3.85TTHH2406 pKa = 6.42LQYY2409 pKa = 11.32APNAIKK2415 pKa = 9.89TDD2417 pKa = 3.58GTEE2420 pKa = 4.13TEE2422 pKa = 4.31LKK2424 pKa = 9.84EE2425 pKa = 4.0LASGDD2430 pKa = 3.51VEE2432 pKa = 5.05KK2433 pKa = 11.05IMGAISDD2440 pKa = 4.05YY2441 pKa = 11.35AAGGLEE2447 pKa = 4.19FVKK2450 pKa = 10.83SQAEE2454 pKa = 4.32KK2455 pKa = 10.63IKK2457 pKa = 9.57TAPLFKK2463 pKa = 10.71EE2464 pKa = 3.69NAEE2467 pKa = 3.97AAKK2470 pKa = 10.63GYY2472 pKa = 7.13VQKK2475 pKa = 11.06FIDD2478 pKa = 3.67SLIEE2482 pKa = 3.94NKK2484 pKa = 10.52EE2485 pKa = 3.75EE2486 pKa = 4.16IIRR2489 pKa = 11.84YY2490 pKa = 7.49GLWGTHH2496 pKa = 3.78TALYY2500 pKa = 10.29KK2501 pKa = 10.84SIAARR2506 pKa = 11.84LGHH2509 pKa = 5.63EE2510 pKa = 4.18TAFATLVLKK2519 pKa = 9.93WLAFGGEE2526 pKa = 4.46SVSDD2530 pKa = 3.73HH2531 pKa = 5.91VKK2533 pKa = 9.91QAAVDD2538 pKa = 3.8LVVYY2542 pKa = 9.96YY2543 pKa = 10.87VMNKK2547 pKa = 9.73PSFPGDD2553 pKa = 3.42SEE2555 pKa = 4.39TQQEE2559 pKa = 4.21GRR2561 pKa = 11.84RR2562 pKa = 11.84FVASLFISALATYY2575 pKa = 8.07TYY2577 pKa = 9.07KK2578 pKa = 9.39TWNYY2582 pKa = 8.88HH2583 pKa = 4.73NLSKK2587 pKa = 10.92VVEE2590 pKa = 4.14PALAYY2595 pKa = 10.45LPYY2598 pKa = 9.59ATSALKK2604 pKa = 10.23MFTPTRR2610 pKa = 11.84LEE2612 pKa = 4.09SVVILSTTIYY2622 pKa = 9.06KK2623 pKa = 9.82TYY2625 pKa = 10.94LSIRR2629 pKa = 11.84KK2630 pKa = 8.83GKK2632 pKa = 10.32SDD2634 pKa = 3.4GLLGTGISAAMEE2646 pKa = 4.0ILSQNPVSVGISVMLGVGAIAAHH2669 pKa = 5.76NAIEE2673 pKa = 4.12SSEE2676 pKa = 4.04QKK2678 pKa = 9.15RR2679 pKa = 11.84TLLMKK2684 pKa = 10.23VFVKK2688 pKa = 10.87NFLDD2692 pKa = 3.73QAATDD2697 pKa = 3.92EE2698 pKa = 4.37LVKK2701 pKa = 10.75EE2702 pKa = 4.17NPEE2705 pKa = 4.28KK2706 pKa = 10.47IIMALFEE2713 pKa = 4.24AVQTIGNPLRR2723 pKa = 11.84LIYY2726 pKa = 10.16HH2727 pKa = 7.2LYY2729 pKa = 8.76GVYY2732 pKa = 10.53YY2733 pKa = 10.11KK2734 pKa = 10.76GWEE2737 pKa = 3.92AKK2739 pKa = 9.77EE2740 pKa = 3.87LSEE2743 pKa = 4.17RR2744 pKa = 11.84TAGRR2748 pKa = 11.84NLFTLIMFEE2757 pKa = 4.03AFEE2760 pKa = 4.29LLGMDD2765 pKa = 3.41SQGKK2769 pKa = 8.77IRR2771 pKa = 11.84NLSGNYY2777 pKa = 9.52ILDD2780 pKa = 5.09LIYY2783 pKa = 10.87GLHH2786 pKa = 5.45KK2787 pKa = 10.5QINRR2791 pKa = 11.84GLKK2794 pKa = 10.41KK2795 pKa = 9.75MVLGWAPAPFSCDD2808 pKa = 2.41WTPSDD2813 pKa = 4.09EE2814 pKa = 4.9RR2815 pKa = 11.84IRR2817 pKa = 11.84LPTDD2821 pKa = 2.73NYY2823 pKa = 10.71LRR2825 pKa = 11.84VEE2827 pKa = 4.36TRR2829 pKa = 11.84CPCGYY2834 pKa = 10.42EE2835 pKa = 3.61MKK2837 pKa = 10.55AFKK2840 pKa = 10.78NVGGKK2845 pKa = 7.38LTKK2848 pKa = 10.25VEE2850 pKa = 4.03EE2851 pKa = 4.47SGPFLCRR2858 pKa = 11.84NRR2860 pKa = 11.84PGRR2863 pKa = 11.84GPVNYY2868 pKa = 9.76RR2869 pKa = 11.84VTKK2872 pKa = 10.77YY2873 pKa = 10.84YY2874 pKa = 10.74DD2875 pKa = 3.44DD2876 pKa = 3.87NLRR2879 pKa = 11.84EE2880 pKa = 4.17IKK2882 pKa = 10.17PVAKK2886 pKa = 10.69LEE2888 pKa = 4.26GQVEE2892 pKa = 4.58HH2893 pKa = 6.82YY2894 pKa = 10.35YY2895 pKa = 10.91KK2896 pKa = 10.98GVTAKK2901 pKa = 9.87IDD2903 pKa = 3.59YY2904 pKa = 10.72SKK2906 pKa = 11.58GKK2908 pKa = 8.82MLLATDD2914 pKa = 3.16KK2915 pKa = 10.92WEE2917 pKa = 4.15VEE2919 pKa = 4.0HH2920 pKa = 7.32GVITRR2925 pKa = 11.84LAKK2928 pKa = 10.24RR2929 pKa = 11.84YY2930 pKa = 8.18TGVGFNGAYY2939 pKa = 10.57LGDD2942 pKa = 4.19EE2943 pKa = 4.36PNHH2946 pKa = 6.05RR2947 pKa = 11.84ALVEE2951 pKa = 4.1RR2952 pKa = 11.84DD2953 pKa = 3.14CATITKK2959 pKa = 8.64NTVQFLKK2966 pKa = 9.92MKK2968 pKa = 9.76KK2969 pKa = 9.75GCAFTYY2975 pKa = 10.77DD2976 pKa = 3.71LTISNLTRR2984 pKa = 11.84LIEE2987 pKa = 4.08LVHH2990 pKa = 6.61RR2991 pKa = 11.84NNLEE2995 pKa = 3.95EE2996 pKa = 4.73KK2997 pKa = 9.54EE2998 pKa = 4.23IPTATVTTWLAYY3010 pKa = 9.18TFVNEE3015 pKa = 4.55DD3016 pKa = 3.02VGTIKK3021 pKa = 10.45PVLGEE3026 pKa = 4.05RR3027 pKa = 11.84VIPDD3031 pKa = 3.47PVVDD3035 pKa = 4.3INLQPEE3041 pKa = 4.5VQVDD3045 pKa = 3.69TSEE3048 pKa = 4.03VGITIIGRR3056 pKa = 11.84EE3057 pKa = 3.99TLMTTGVTPVLEE3069 pKa = 4.25KK3070 pKa = 11.01VEE3072 pKa = 4.64PDD3074 pKa = 3.24ASDD3077 pKa = 3.28NQNSVKK3083 pKa = 10.38IGLDD3087 pKa = 3.0EE3088 pKa = 4.64GNYY3091 pKa = 8.99PGPGIQTHH3099 pKa = 5.72TLTEE3103 pKa = 4.66EE3104 pKa = 3.51IHH3106 pKa = 6.37NRR3108 pKa = 11.84DD3109 pKa = 3.39ARR3111 pKa = 11.84PFIMILGSRR3120 pKa = 11.84NSISNRR3126 pKa = 11.84AKK3128 pKa = 8.99TARR3131 pKa = 11.84NINLYY3136 pKa = 9.12TGNDD3140 pKa = 3.2PRR3142 pKa = 11.84EE3143 pKa = 4.1IRR3145 pKa = 11.84DD3146 pKa = 3.37LMAAGRR3152 pKa = 11.84MLVVALRR3159 pKa = 11.84DD3160 pKa = 3.52VDD3162 pKa = 4.14PEE3164 pKa = 4.06LSEE3167 pKa = 4.07MVDD3170 pKa = 3.83FKK3172 pKa = 11.42GTFLDD3177 pKa = 4.4RR3178 pKa = 11.84EE3179 pKa = 4.24ALEE3182 pKa = 4.48ALSLGQPKK3190 pKa = 9.66PKK3192 pKa = 10.06QVTKK3196 pKa = 10.25EE3197 pKa = 3.73AVRR3200 pKa = 11.84NLIEE3204 pKa = 3.96QKK3206 pKa = 10.71KK3207 pKa = 10.47DD3208 pKa = 3.25VEE3210 pKa = 4.26IPNWFASDD3218 pKa = 3.76DD3219 pKa = 3.92PVFLEE3224 pKa = 4.85VALKK3228 pKa = 9.85NDD3230 pKa = 2.94KK3231 pKa = 10.73YY3232 pKa = 11.53YY3233 pKa = 11.26LVGDD3237 pKa = 3.63VGEE3240 pKa = 5.26LKK3242 pKa = 10.8DD3243 pKa = 3.43QAKK3246 pKa = 10.68ALGATDD3252 pKa = 3.05QTRR3255 pKa = 11.84IIKK3258 pKa = 9.81EE3259 pKa = 4.08VGSRR3263 pKa = 11.84TYY3265 pKa = 11.65AMKK3268 pKa = 10.65LSSWFLKK3275 pKa = 10.69ASNKK3279 pKa = 9.54QMSLTPLFEE3288 pKa = 4.57EE3289 pKa = 4.82LLLRR3293 pKa = 11.84CPPATKK3299 pKa = 10.3SNKK3302 pKa = 8.82GHH3304 pKa = 6.29MASAYY3309 pKa = 10.17QLAQGNWEE3317 pKa = 3.88PLGCGVHH3324 pKa = 6.69LGTIPARR3331 pKa = 11.84RR3332 pKa = 11.84VKK3334 pKa = 9.66IHH3336 pKa = 6.99PYY3338 pKa = 9.36EE3339 pKa = 5.22AYY3341 pKa = 10.63LKK3343 pKa = 10.47LKK3345 pKa = 10.72DD3346 pKa = 4.63FIEE3349 pKa = 4.52EE3350 pKa = 4.11EE3351 pKa = 4.16EE3352 pKa = 4.16KK3353 pKa = 10.81KK3354 pKa = 10.51PRR3356 pKa = 11.84VKK3358 pKa = 10.21DD3359 pKa = 3.41TVIRR3363 pKa = 11.84EE3364 pKa = 4.05HH3365 pKa = 6.63NKK3367 pKa = 9.55WILKK3371 pKa = 9.93KK3372 pKa = 10.36IRR3374 pKa = 11.84FQGNLNTKK3382 pKa = 10.2KK3383 pKa = 9.8MLNPGKK3389 pKa = 10.35LSEE3392 pKa = 4.04QLDD3395 pKa = 3.74RR3396 pKa = 11.84EE3397 pKa = 4.33GRR3399 pKa = 11.84KK3400 pKa = 9.69RR3401 pKa = 11.84NIYY3404 pKa = 8.67NHH3406 pKa = 6.29QIGTIMSSAGIRR3418 pKa = 11.84LEE3420 pKa = 3.66KK3421 pKa = 10.74LPIVRR3426 pKa = 11.84AQTDD3430 pKa = 3.31TKK3432 pKa = 10.07TFHH3435 pKa = 6.09EE3436 pKa = 5.1AIRR3439 pKa = 11.84DD3440 pKa = 3.96KK3441 pKa = 10.75IDD3443 pKa = 3.31KK3444 pKa = 10.65SEE3446 pKa = 3.82NRR3448 pKa = 11.84QNPEE3452 pKa = 3.63LHH3454 pKa = 6.53NKK3456 pKa = 9.61LLEE3459 pKa = 4.33IFHH3462 pKa = 6.81TIAQPTLKK3470 pKa = 8.89HH3471 pKa = 5.8TYY3473 pKa = 11.01GEE3475 pKa = 4.56VTWEE3479 pKa = 3.73QLEE3482 pKa = 4.19AGVNRR3487 pKa = 11.84KK3488 pKa = 8.53GAAGFLEE3495 pKa = 4.29KK3496 pKa = 10.87KK3497 pKa = 10.67NIGEE3501 pKa = 4.07VLDD3504 pKa = 4.09SEE3506 pKa = 4.46KK3507 pKa = 10.99HH3508 pKa = 5.47LVEE3511 pKa = 4.37QLVRR3515 pKa = 11.84DD3516 pKa = 4.36LKK3518 pKa = 10.87AGRR3521 pKa = 11.84KK3522 pKa = 7.6IKK3524 pKa = 10.55YY3525 pKa = 9.53YY3526 pKa = 9.35EE3527 pKa = 3.67TAIPKK3532 pKa = 9.65NEE3534 pKa = 3.99KK3535 pKa = 10.09RR3536 pKa = 11.84DD3537 pKa = 4.15VSDD3540 pKa = 3.47DD3541 pKa = 3.29WQAGDD3546 pKa = 3.83LVVEE3550 pKa = 4.15KK3551 pKa = 10.22RR3552 pKa = 11.84PRR3554 pKa = 11.84VIQYY3558 pKa = 9.86PEE3560 pKa = 3.77AKK3562 pKa = 9.03TRR3564 pKa = 11.84LAITKK3569 pKa = 9.68VMYY3572 pKa = 10.46NWVKK3576 pKa = 9.42QQPVVIPGYY3585 pKa = 9.68EE3586 pKa = 4.0GKK3588 pKa = 8.33TPLFNIFDD3596 pKa = 4.19KK3597 pKa = 11.07VRR3599 pKa = 11.84KK3600 pKa = 9.09EE3601 pKa = 3.34WDD3603 pKa = 3.44SFNEE3607 pKa = 3.9PVAVSFDD3614 pKa = 3.36TKK3616 pKa = 11.12AWDD3619 pKa = 3.73TQVTSKK3625 pKa = 10.85DD3626 pKa = 3.33LQLIGEE3632 pKa = 4.19IQKK3635 pKa = 10.83YY3636 pKa = 8.05YY3637 pKa = 10.42YY3638 pKa = 10.05KK3639 pKa = 10.64KK3640 pKa = 9.4EE3641 pKa = 3.45WHH3643 pKa = 6.59KK3644 pKa = 11.08FIDD3647 pKa = 4.45TITDD3651 pKa = 2.84HH3652 pKa = 5.41MTEE3655 pKa = 4.29VPVITADD3662 pKa = 3.48GEE3664 pKa = 4.61VYY3666 pKa = 10.09IRR3668 pKa = 11.84NGQRR3672 pKa = 11.84GSGQPDD3678 pKa = 3.48TSAGNSMLNVLTMMYY3693 pKa = 9.3GFCEE3697 pKa = 4.43STGVPYY3703 pKa = 10.78KK3704 pKa = 10.66SFNRR3708 pKa = 11.84VARR3711 pKa = 11.84IHH3713 pKa = 6.09VCGDD3717 pKa = 3.2DD3718 pKa = 3.59GFLITEE3724 pKa = 4.61KK3725 pKa = 11.12GLGLKK3730 pKa = 9.49FANKK3734 pKa = 9.37GMQILHH3740 pKa = 6.5EE3741 pKa = 4.61AGKK3744 pKa = 8.28PQKK3747 pKa = 9.05ITEE3750 pKa = 4.09GEE3752 pKa = 4.21KK3753 pKa = 9.99MKK3755 pKa = 10.64VAYY3758 pKa = 9.93RR3759 pKa = 11.84FEE3761 pKa = 6.63DD3762 pKa = 3.49IEE3764 pKa = 4.64FCSHH3768 pKa = 5.71TPVPVRR3774 pKa = 11.84WSDD3777 pKa = 3.28NTSSHH3782 pKa = 5.01MAGRR3786 pKa = 11.84DD3787 pKa = 3.24TAVILSKK3794 pKa = 10.27MATRR3798 pKa = 11.84LDD3800 pKa = 3.66SSGEE3804 pKa = 4.1RR3805 pKa = 11.84GTTAYY3810 pKa = 9.28EE3811 pKa = 3.82KK3812 pKa = 10.75AVAFSFLLMYY3822 pKa = 10.28SWNPLVRR3829 pKa = 11.84RR3830 pKa = 11.84ICLLVLSQQPEE3841 pKa = 4.15TDD3843 pKa = 3.59PSKK3846 pKa = 10.75HH3847 pKa = 4.24ATYY3850 pKa = 10.15YY3851 pKa = 10.93YY3852 pKa = 10.67KK3853 pKa = 10.69GDD3855 pKa = 4.37PIGAYY3860 pKa = 9.61KK3861 pKa = 10.53DD3862 pKa = 3.56VIGRR3866 pKa = 11.84NLSEE3870 pKa = 4.29LKK3872 pKa = 9.68RR3873 pKa = 11.84TGFEE3877 pKa = 3.83KK3878 pKa = 10.7LANLNLSLSTLGVWTKK3894 pKa = 9.02HH3895 pKa = 3.65TSKK3898 pKa = 10.81RR3899 pKa = 11.84IIQDD3903 pKa = 3.14CVAIGKK3909 pKa = 9.58EE3910 pKa = 3.89EE3911 pKa = 4.28GNWLVKK3917 pKa = 9.67PDD3919 pKa = 3.96RR3920 pKa = 11.84LISSKK3925 pKa = 9.57TGHH3928 pKa = 7.19LYY3930 pKa = 10.26IPDD3933 pKa = 3.79KK3934 pKa = 11.36GFTLQGKK3941 pKa = 9.3HH3942 pKa = 5.55YY3943 pKa = 9.61EE3944 pKa = 4.06QLQLRR3949 pKa = 11.84TEE3951 pKa = 4.38TNPVMGVGTEE3961 pKa = 4.19RR3962 pKa = 11.84YY3963 pKa = 9.44KK3964 pKa = 11.03LGPIVNLLLRR3974 pKa = 11.84RR3975 pKa = 11.84LKK3977 pKa = 10.31ILLMTAVGVSSS3988 pKa = 3.53

Molecular weight:
449.16 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|P19711|POLG_BVDVN Genome polyprotein OS=Bovine viral diarrhea virus (isolate NADL) OX=11100 PE=1 SV=2
MM1 pKa = 7.41EE2 pKa = 6.74LITNEE7 pKa = 4.62LLYY10 pKa = 9.4KK11 pKa = 9.83TYY13 pKa = 9.89KK14 pKa = 9.11QKK16 pKa = 10.7PVGVEE21 pKa = 3.81EE22 pKa = 4.22PVYY25 pKa = 10.8DD26 pKa = 4.0QAGDD30 pKa = 3.63PLFGEE35 pKa = 5.1RR36 pKa = 11.84GAVHH40 pKa = 6.19PQSTLKK46 pKa = 10.68LPHH49 pKa = 6.51KK50 pKa = 10.18RR51 pKa = 11.84GEE53 pKa = 4.03RR54 pKa = 11.84DD55 pKa = 3.18VPTNLASLPKK65 pKa = 10.43RR66 pKa = 11.84GDD68 pKa = 3.51CRR70 pKa = 11.84SGNSRR75 pKa = 11.84GPVSGIYY82 pKa = 10.08LKK84 pKa = 10.52PGPLFYY90 pKa = 10.26QDD92 pKa = 3.33YY93 pKa = 9.91KK94 pKa = 11.05GPVYY98 pKa = 10.46HH99 pKa = 7.33RR100 pKa = 11.84APLEE104 pKa = 3.95LFEE107 pKa = 4.98EE108 pKa = 5.6GSMCEE113 pKa = 3.74TTKK116 pKa = 10.73RR117 pKa = 11.84IGRR120 pKa = 11.84VTGSDD125 pKa = 2.65GKK127 pKa = 10.74LYY129 pKa = 10.41HH130 pKa = 7.02IYY132 pKa = 10.63VCIDD136 pKa = 2.83GCIIIKK142 pKa = 10.14SATRR146 pKa = 11.84SYY148 pKa = 10.87QRR150 pKa = 11.84VFRR153 pKa = 11.84WVHH156 pKa = 5.25NRR158 pKa = 11.84LDD160 pKa = 3.76CPLWVTTCSDD170 pKa = 3.5TKK172 pKa = 11.27EE173 pKa = 3.75EE174 pKa = 4.27GATKK178 pKa = 10.54KK179 pKa = 8.99KK180 pKa = 6.95TQKK183 pKa = 9.8PDD185 pKa = 2.97RR186 pKa = 11.84LEE188 pKa = 4.04RR189 pKa = 11.84GKK191 pKa = 10.2MKK193 pKa = 10.29IVPKK197 pKa = 10.38EE198 pKa = 3.93SEE200 pKa = 4.35KK201 pKa = 11.0DD202 pKa = 3.72SKK204 pKa = 9.91TKK206 pKa = 10.63PPDD209 pKa = 3.05ATIVVEE215 pKa = 4.27GVKK218 pKa = 10.48YY219 pKa = 8.33QVRR222 pKa = 11.84KK223 pKa = 9.75KK224 pKa = 11.07GKK226 pKa = 7.62TKK228 pKa = 10.72SKK230 pKa = 8.85NTQDD234 pKa = 3.54GLYY237 pKa = 10.13HH238 pKa = 6.52NKK240 pKa = 9.96NKK242 pKa = 9.57PQEE245 pKa = 4.14SRR247 pKa = 11.84KK248 pKa = 9.96KK249 pKa = 10.59LEE251 pKa = 3.96KK252 pKa = 10.65ALLAWAIIAIVLFQVTMGEE271 pKa = 6.12NITQWNLQDD280 pKa = 4.15NGTEE284 pKa = 4.93GIQRR288 pKa = 11.84AMFQRR293 pKa = 11.84GVNRR297 pKa = 11.84SLHH300 pKa = 6.13GIWPEE305 pKa = 4.1KK306 pKa = 10.07ICTGVPSHH314 pKa = 7.06LATDD318 pKa = 4.03IEE320 pKa = 4.73LKK322 pKa = 9.73TIHH325 pKa = 6.61GMMDD329 pKa = 2.99ASEE332 pKa = 4.21KK333 pKa = 10.28TNYY336 pKa = 7.46TCCRR340 pKa = 11.84LQRR343 pKa = 11.84HH344 pKa = 5.77EE345 pKa = 4.26WNKK348 pKa = 10.67HH349 pKa = 4.0GWCNWYY355 pKa = 10.51NIEE358 pKa = 4.09PWILVMNRR366 pKa = 11.84TQANLTEE373 pKa = 4.42GQPPRR378 pKa = 11.84EE379 pKa = 4.2CAVTCRR385 pKa = 11.84YY386 pKa = 10.25DD387 pKa = 3.27RR388 pKa = 11.84ASDD391 pKa = 3.98LNVVTQARR399 pKa = 11.84DD400 pKa = 3.24SPTPLTGCKK409 pKa = 9.63KK410 pKa = 10.51GKK412 pKa = 9.45NFSFAGILMRR422 pKa = 11.84GPCNFEE428 pKa = 3.5IAASDD433 pKa = 3.74VLFKK437 pKa = 10.38EE438 pKa = 4.47HH439 pKa = 6.15EE440 pKa = 4.83RR441 pKa = 11.84ISMFQDD447 pKa = 2.91TTLYY451 pKa = 11.0LVDD454 pKa = 4.22GLTNSLEE461 pKa = 4.33GARR464 pKa = 11.84QGTAKK469 pKa = 9.65LTTWLGKK476 pKa = 9.55QLGILGKK483 pKa = 10.58KK484 pKa = 9.99LEE486 pKa = 4.64NKK488 pKa = 9.86SKK490 pKa = 8.64TWFGAYY496 pKa = 9.21AASPYY501 pKa = 10.34CDD503 pKa = 3.41VDD505 pKa = 4.19RR506 pKa = 11.84KK507 pKa = 10.22IGYY510 pKa = 8.08IWYY513 pKa = 7.53TKK515 pKa = 10.63NCTPACLPKK524 pKa = 9.26NTKK527 pKa = 9.59IVGPGKK533 pKa = 10.44FGTNAEE539 pKa = 4.3DD540 pKa = 3.83GKK542 pKa = 10.63ILHH545 pKa = 6.58EE546 pKa = 4.44MGGHH550 pKa = 6.07LSEE553 pKa = 4.56VLLLSLVVLSDD564 pKa = 3.92FAPEE568 pKa = 4.12TASVMYY574 pKa = 10.33LILHH578 pKa = 6.01FSIPQSHH585 pKa = 6.48VDD587 pKa = 5.17VMDD590 pKa = 4.6CDD592 pKa = 3.72KK593 pKa = 10.79TQLNLTVEE601 pKa = 4.5LTTAEE606 pKa = 4.42VIPGSVWNLGKK617 pKa = 10.13YY618 pKa = 9.24VCIRR622 pKa = 11.84PNWWPYY628 pKa = 7.13EE629 pKa = 4.26TTVVLAFEE637 pKa = 4.61EE638 pKa = 4.81VSQVVKK644 pKa = 10.68LVLRR648 pKa = 11.84ALRR651 pKa = 11.84DD652 pKa = 3.38LTRR655 pKa = 11.84IWNAATTTAFLVCLVKK671 pKa = 10.38IVRR674 pKa = 11.84GQMVQGILWLLLITGVQGHH693 pKa = 7.11LDD695 pKa = 3.8CKK697 pKa = 10.81PEE699 pKa = 3.85FSYY702 pKa = 11.22AIAKK706 pKa = 9.68DD707 pKa = 3.59EE708 pKa = 5.35RR709 pKa = 11.84IGQLGAEE716 pKa = 4.57GLTTTWKK723 pKa = 10.29EE724 pKa = 3.76YY725 pKa = 10.45SPGMKK730 pKa = 10.27LEE732 pKa = 4.12DD733 pKa = 3.32TMVIAWCEE741 pKa = 3.97DD742 pKa = 2.9GKK744 pKa = 11.61LMYY747 pKa = 10.26LQRR750 pKa = 11.84CTRR753 pKa = 11.84EE754 pKa = 3.7TRR756 pKa = 11.84YY757 pKa = 10.0LAILHH762 pKa = 5.65TRR764 pKa = 11.84ALPTSVVFKK773 pKa = 10.91KK774 pKa = 10.85LFDD777 pKa = 3.52GRR779 pKa = 11.84KK780 pKa = 8.57QEE782 pKa = 5.49DD783 pKa = 3.99VVEE786 pKa = 4.23MNDD789 pKa = 3.13NFEE792 pKa = 5.69FGLCPCDD799 pKa = 3.09AKK801 pKa = 10.98PIVRR805 pKa = 11.84GKK807 pKa = 11.06FNTTLLNGPAFQMVCPIGWTGTVSCTSFNMDD838 pKa = 3.25TLATTVVRR846 pKa = 11.84TYY848 pKa = 10.73RR849 pKa = 11.84RR850 pKa = 11.84SKK852 pKa = 10.26PFPHH856 pKa = 6.63RR857 pKa = 11.84QGCITQKK864 pKa = 11.02NLGEE868 pKa = 4.55DD869 pKa = 3.51LHH871 pKa = 8.05NCILGGNWTCVPGDD885 pKa = 3.36QLLYY889 pKa = 10.49KK890 pKa = 10.21GGSIEE895 pKa = 4.07SCKK898 pKa = 8.95WCGYY902 pKa = 6.98QFKK905 pKa = 10.12EE906 pKa = 4.79SEE908 pKa = 4.48GLPHH912 pKa = 6.82YY913 pKa = 10.14PIGKK917 pKa = 9.32CKK919 pKa = 10.69LEE921 pKa = 4.12NEE923 pKa = 4.05TGYY926 pKa = 11.28RR927 pKa = 11.84LVDD930 pKa = 3.34STSCNRR936 pKa = 11.84EE937 pKa = 3.24GVAIVPQGTLKK948 pKa = 10.89CKK950 pKa = 9.98IGKK953 pKa = 6.63TTVQVIAMDD962 pKa = 4.04TKK964 pKa = 10.6LGPMPCRR971 pKa = 11.84PYY973 pKa = 10.71EE974 pKa = 4.51IISSEE979 pKa = 4.29GPVEE983 pKa = 4.0KK984 pKa = 9.47TACTFNYY991 pKa = 8.82TKK993 pKa = 9.86TLKK996 pKa = 10.55NKK998 pKa = 9.56YY999 pKa = 9.45FEE1001 pKa = 4.9PRR1003 pKa = 11.84DD1004 pKa = 3.8SYY1006 pKa = 10.55FQQYY1010 pKa = 7.2MLKK1013 pKa = 10.68GEE1015 pKa = 3.98YY1016 pKa = 9.97QYY1018 pKa = 11.36WFDD1021 pKa = 5.68LEE1023 pKa = 4.6VTDD1026 pKa = 4.22HH1027 pKa = 6.42HH1028 pKa = 7.2RR1029 pKa = 11.84DD1030 pKa = 3.46YY1031 pKa = 10.69FAEE1034 pKa = 4.69SILVVVVALLGGRR1047 pKa = 11.84YY1048 pKa = 8.74VLWLLVTYY1056 pKa = 9.29MVLSEE1061 pKa = 4.04QKK1063 pKa = 10.97ALGIQYY1069 pKa = 10.82GSGEE1073 pKa = 4.26VVMMGNLLTHH1083 pKa = 6.35NNIEE1087 pKa = 4.21VVTYY1091 pKa = 9.57FLLLYY1096 pKa = 10.57LLLRR1100 pKa = 11.84EE1101 pKa = 4.2EE1102 pKa = 4.7SVKK1105 pKa = 10.59KK1106 pKa = 9.55WVLLLYY1112 pKa = 10.15HH1113 pKa = 7.0ILVVHH1118 pKa = 6.85PIKK1121 pKa = 10.8SVIVILLMIGDD1132 pKa = 4.1VVKK1135 pKa = 10.82ADD1137 pKa = 3.68SGGQEE1142 pKa = 4.0YY1143 pKa = 10.58LGKK1146 pKa = 9.81IDD1148 pKa = 4.33LCFTTVVLIVIGLIIARR1165 pKa = 11.84RR1166 pKa = 11.84DD1167 pKa = 3.49PTIVPLVTIMAALRR1181 pKa = 11.84VTEE1184 pKa = 4.5LTHH1187 pKa = 6.74QPGVDD1192 pKa = 2.75IAVAVMTITLLMVSYY1207 pKa = 9.15VTDD1210 pKa = 3.18YY1211 pKa = 11.0FRR1213 pKa = 11.84YY1214 pKa = 9.9KK1215 pKa = 10.42KK1216 pKa = 9.28WLQCILSLVSAVFLIRR1232 pKa = 11.84SLIYY1236 pKa = 10.11LGRR1239 pKa = 11.84IEE1241 pKa = 4.44MPEE1244 pKa = 3.57VTIPNWRR1251 pKa = 11.84PLTLILLYY1259 pKa = 10.63LISTTIVTRR1268 pKa = 11.84WKK1270 pKa = 10.58VDD1272 pKa = 3.25VAGLLLQCVPILLLVTTLWADD1293 pKa = 4.13FLTLILILPTYY1304 pKa = 9.99EE1305 pKa = 4.28LVKK1308 pKa = 10.49LYY1310 pKa = 10.36YY1311 pKa = 10.39LKK1313 pKa = 9.76TVRR1316 pKa = 11.84TDD1318 pKa = 3.47TEE1320 pKa = 4.34RR1321 pKa = 11.84SWLGGIDD1328 pKa = 3.63YY1329 pKa = 9.36TRR1331 pKa = 11.84VDD1333 pKa = 3.57SIYY1336 pKa = 11.05DD1337 pKa = 3.29VDD1339 pKa = 3.74EE1340 pKa = 4.92SGEE1343 pKa = 4.23GVYY1346 pKa = 10.49LFPSRR1351 pKa = 11.84QKK1353 pKa = 10.59AQGNFSILLPLIKK1366 pKa = 9.73ATLISCVSSKK1376 pKa = 9.44WQLIYY1381 pKa = 10.31MSYY1384 pKa = 9.29LTLDD1388 pKa = 3.58FMYY1391 pKa = 10.85YY1392 pKa = 6.66MHH1394 pKa = 7.33RR1395 pKa = 11.84KK1396 pKa = 9.12VIEE1399 pKa = 4.64EE1400 pKa = 3.8ISGGTNIISRR1410 pKa = 11.84LVAALIEE1417 pKa = 4.96LNWSMEE1423 pKa = 4.07EE1424 pKa = 4.11EE1425 pKa = 4.06EE1426 pKa = 4.97SKK1428 pKa = 11.04GLKK1431 pKa = 9.87KK1432 pKa = 10.57FYY1434 pKa = 10.51LLSGRR1439 pKa = 11.84LRR1441 pKa = 11.84NLIIKK1446 pKa = 9.67HH1447 pKa = 4.95KK1448 pKa = 10.31VRR1450 pKa = 11.84NEE1452 pKa = 4.18TVASWYY1458 pKa = 10.77GEE1460 pKa = 3.99EE1461 pKa = 4.41EE1462 pKa = 4.82VYY1464 pKa = 11.12GMPKK1468 pKa = 9.84IMTIIKK1474 pKa = 10.35ASTLSKK1480 pKa = 10.45SRR1482 pKa = 11.84HH1483 pKa = 5.93CIICTVCEE1491 pKa = 3.82GRR1493 pKa = 11.84EE1494 pKa = 4.29WKK1496 pKa = 10.8GGTCPKK1502 pKa = 9.94CGRR1505 pKa = 11.84HH1506 pKa = 5.56GKK1508 pKa = 9.47PITCGMSLADD1518 pKa = 4.02FEE1520 pKa = 4.36EE1521 pKa = 4.17RR1522 pKa = 11.84HH1523 pKa = 5.64YY1524 pKa = 11.36KK1525 pKa = 10.34RR1526 pKa = 11.84IFIRR1530 pKa = 11.84EE1531 pKa = 4.08GNFEE1535 pKa = 4.33GMCSRR1540 pKa = 11.84CQGKK1544 pKa = 8.5HH1545 pKa = 4.94RR1546 pKa = 11.84RR1547 pKa = 11.84FEE1549 pKa = 3.89MDD1551 pKa = 3.94RR1552 pKa = 11.84EE1553 pKa = 4.32PKK1555 pKa = 9.15SARR1558 pKa = 11.84YY1559 pKa = 8.76CAEE1562 pKa = 4.06CNRR1565 pKa = 11.84LHH1567 pKa = 6.65PAEE1570 pKa = 5.35EE1571 pKa = 4.25GDD1573 pKa = 3.94FWAEE1577 pKa = 3.63SSMLGLKK1584 pKa = 8.2ITYY1587 pKa = 8.35FALMDD1592 pKa = 3.85GKK1594 pKa = 11.16VYY1596 pKa = 10.65DD1597 pKa = 3.45ITEE1600 pKa = 3.88WAGCQRR1606 pKa = 11.84VGISPDD1612 pKa = 3.07THH1614 pKa = 6.82RR1615 pKa = 11.84VPCHH1619 pKa = 5.71ISFGSRR1625 pKa = 11.84MPFRR1629 pKa = 11.84QEE1631 pKa = 3.44YY1632 pKa = 10.32NGFVQYY1638 pKa = 7.76TARR1641 pKa = 11.84GQLFLRR1647 pKa = 11.84NLPVLATKK1655 pKa = 10.78VKK1657 pKa = 9.45MLMVGNLGEE1666 pKa = 4.38EE1667 pKa = 4.2IGNLEE1672 pKa = 3.89HH1673 pKa = 7.03LGWILRR1679 pKa = 11.84GPAVCKK1685 pKa = 10.48KK1686 pKa = 8.65ITEE1689 pKa = 4.21HH1690 pKa = 6.35EE1691 pKa = 4.25KK1692 pKa = 10.34CHH1694 pKa = 7.42INILDD1699 pKa = 3.77KK1700 pKa = 10.62LTAFFGIMPRR1710 pKa = 11.84GTTPRR1715 pKa = 11.84APVRR1719 pKa = 11.84FPTSLLKK1726 pKa = 10.4VRR1728 pKa = 11.84RR1729 pKa = 11.84GLEE1732 pKa = 3.9TAWAYY1737 pKa = 6.64THH1739 pKa = 6.28QGGISSVDD1747 pKa = 3.13HH1748 pKa = 5.0VTAGKK1753 pKa = 10.16DD1754 pKa = 3.45LLVCDD1759 pKa = 3.45SMGRR1763 pKa = 11.84TRR1765 pKa = 11.84VVCQSNNRR1773 pKa = 11.84LTDD1776 pKa = 3.32EE1777 pKa = 4.26TEE1779 pKa = 4.22YY1780 pKa = 11.29GVKK1783 pKa = 9.44TDD1785 pKa = 3.77SGCPDD1790 pKa = 3.59GARR1793 pKa = 11.84CYY1795 pKa = 10.55VLNPEE1800 pKa = 4.53AVNISGSKK1808 pKa = 9.47GAVVHH1813 pKa = 5.68LQKK1816 pKa = 9.97TGGEE1820 pKa = 4.5FTCVTASGTPAFFDD1834 pKa = 4.19LKK1836 pKa = 10.87NLKK1839 pKa = 9.3GWSGLPIFEE1848 pKa = 4.7ASSGRR1853 pKa = 11.84VVGRR1857 pKa = 11.84VKK1859 pKa = 10.55VGKK1862 pKa = 9.99NEE1864 pKa = 3.77EE1865 pKa = 4.22SKK1867 pKa = 9.14PTKK1870 pKa = 10.02IMSGIQTVSKK1880 pKa = 10.79NRR1882 pKa = 11.84ADD1884 pKa = 3.46LTEE1887 pKa = 4.11MVKK1890 pKa = 10.53KK1891 pKa = 8.4ITSMNRR1897 pKa = 11.84GDD1899 pKa = 4.11FKK1901 pKa = 11.2QITLATGAGKK1911 pKa = 7.33TTEE1914 pKa = 4.17LPKK1917 pKa = 10.84AVIEE1921 pKa = 4.36EE1922 pKa = 4.12IGRR1925 pKa = 11.84HH1926 pKa = 4.72KK1927 pKa = 10.47RR1928 pKa = 11.84VLVLIPLRR1936 pKa = 11.84AAAEE1940 pKa = 4.05SVYY1943 pKa = 10.7QYY1945 pKa = 10.44MRR1947 pKa = 11.84LKK1949 pKa = 10.55HH1950 pKa = 5.79PSISFNLRR1958 pKa = 11.84IGDD1961 pKa = 3.78MKK1963 pKa = 10.67EE1964 pKa = 3.53GDD1966 pKa = 3.78MATGITYY1973 pKa = 10.43ASYY1976 pKa = 10.71GYY1978 pKa = 9.22FCQMPQPKK1986 pKa = 9.4LRR1988 pKa = 11.84AAMVEE1993 pKa = 3.71YY1994 pKa = 10.51SYY1996 pKa = 11.48IFLDD2000 pKa = 4.62EE2001 pKa = 4.17YY2002 pKa = 11.34HH2003 pKa = 7.01CATPEE2008 pKa = 3.58QLAIIGKK2015 pKa = 6.99IHH2017 pKa = 6.95RR2018 pKa = 11.84FSEE2021 pKa = 4.56SIRR2024 pKa = 11.84VVAMTATPAGSVTTTGQKK2042 pKa = 10.29HH2043 pKa = 6.11PIEE2046 pKa = 4.35EE2047 pKa = 4.85FIAPEE2052 pKa = 4.02VMKK2055 pKa = 11.22GEE2057 pKa = 4.31DD2058 pKa = 4.0LGSQFLDD2065 pKa = 2.94IAGLKK2070 pKa = 10.17IPVDD2074 pKa = 3.64EE2075 pKa = 4.83MKK2077 pKa = 11.25GNMLVFVPTRR2087 pKa = 11.84NMAVEE2092 pKa = 4.11VAKK2095 pKa = 10.61KK2096 pKa = 10.32LKK2098 pKa = 10.7AKK2100 pKa = 10.02GYY2102 pKa = 9.43NSGYY2106 pKa = 9.53YY2107 pKa = 9.94YY2108 pKa = 10.81SGEE2111 pKa = 4.04DD2112 pKa = 3.5PANLRR2117 pKa = 11.84VVTSQSPYY2125 pKa = 10.84VIVATNAIEE2134 pKa = 4.44SGVTLPDD2141 pKa = 4.12LDD2143 pKa = 4.14TVIDD2147 pKa = 3.75TGLKK2151 pKa = 8.46CEE2153 pKa = 3.79KK2154 pKa = 9.92RR2155 pKa = 11.84VRR2157 pKa = 11.84VSSKK2161 pKa = 10.1IPFIVTGLKK2170 pKa = 10.35RR2171 pKa = 11.84MAVTVGEE2178 pKa = 4.11QAQRR2182 pKa = 11.84RR2183 pKa = 11.84GRR2185 pKa = 11.84VGRR2188 pKa = 11.84VKK2190 pKa = 10.24PGRR2193 pKa = 11.84YY2194 pKa = 8.98YY2195 pKa = 10.84RR2196 pKa = 11.84SQEE2199 pKa = 3.93TATGSKK2205 pKa = 10.16DD2206 pKa = 3.27YY2207 pKa = 10.94HH2208 pKa = 6.9YY2209 pKa = 11.34DD2210 pKa = 3.2LLQAQRR2216 pKa = 11.84YY2217 pKa = 8.49GIEE2220 pKa = 4.21DD2221 pKa = 4.92GINVTKK2227 pKa = 10.54SFRR2230 pKa = 11.84EE2231 pKa = 3.95MNYY2234 pKa = 10.12DD2235 pKa = 2.79WSLYY2239 pKa = 10.66EE2240 pKa = 4.56EE2241 pKa = 5.14DD2242 pKa = 4.9SLLITQLEE2250 pKa = 4.21ILNNLLISEE2259 pKa = 4.96DD2260 pKa = 3.34LPAAVKK2266 pKa = 10.78NIMARR2271 pKa = 11.84TDD2273 pKa = 3.38HH2274 pKa = 7.2PEE2276 pKa = 4.72PIQLAYY2282 pKa = 10.72NSYY2285 pKa = 8.86EE2286 pKa = 3.89VQVPVLFPKK2295 pKa = 10.05IRR2297 pKa = 11.84NGEE2300 pKa = 4.05VTDD2303 pKa = 3.69TYY2305 pKa = 11.55EE2306 pKa = 4.41NYY2308 pKa = 10.84SFLNARR2314 pKa = 11.84KK2315 pKa = 9.63LGEE2318 pKa = 4.39DD2319 pKa = 3.56VPVYY2323 pKa = 10.17IYY2325 pKa = 10.16ATEE2328 pKa = 4.6DD2329 pKa = 3.09EE2330 pKa = 4.93DD2331 pKa = 5.36LAVDD2335 pKa = 5.31LLGLDD2340 pKa = 3.5WPDD2343 pKa = 4.02PGNQQVVEE2351 pKa = 4.14TGKK2354 pKa = 10.61ALKK2357 pKa = 10.14QVTGLSSAEE2366 pKa = 3.96NALLVALFGYY2376 pKa = 9.85VGYY2379 pKa = 10.05QALSKK2384 pKa = 10.33RR2385 pKa = 11.84HH2386 pKa = 5.26VPMITDD2392 pKa = 3.73IYY2394 pKa = 9.59TIEE2397 pKa = 4.16DD2398 pKa = 3.24QRR2400 pKa = 11.84LEE2402 pKa = 4.35DD2403 pKa = 3.85TTHH2406 pKa = 6.42LQYY2409 pKa = 11.32APNAIKK2415 pKa = 9.89TDD2417 pKa = 3.58GTEE2420 pKa = 4.13TEE2422 pKa = 4.31LKK2424 pKa = 9.84EE2425 pKa = 4.0LASGDD2430 pKa = 3.51VEE2432 pKa = 5.05KK2433 pKa = 11.05IMGAISDD2440 pKa = 4.05YY2441 pKa = 11.35AAGGLEE2447 pKa = 4.19FVKK2450 pKa = 10.83SQAEE2454 pKa = 4.32KK2455 pKa = 10.63IKK2457 pKa = 9.57TAPLFKK2463 pKa = 10.71EE2464 pKa = 3.69NAEE2467 pKa = 3.97AAKK2470 pKa = 10.63GYY2472 pKa = 7.13VQKK2475 pKa = 11.06FIDD2478 pKa = 3.67SLIEE2482 pKa = 3.94NKK2484 pKa = 10.52EE2485 pKa = 3.75EE2486 pKa = 4.16IIRR2489 pKa = 11.84YY2490 pKa = 7.49GLWGTHH2496 pKa = 3.78TALYY2500 pKa = 10.29KK2501 pKa = 10.84SIAARR2506 pKa = 11.84LGHH2509 pKa = 5.63EE2510 pKa = 4.18TAFATLVLKK2519 pKa = 9.93WLAFGGEE2526 pKa = 4.46SVSDD2530 pKa = 3.73HH2531 pKa = 5.91VKK2533 pKa = 9.91QAAVDD2538 pKa = 3.8LVVYY2542 pKa = 9.96YY2543 pKa = 10.87VMNKK2547 pKa = 9.73PSFPGDD2553 pKa = 3.42SEE2555 pKa = 4.39TQQEE2559 pKa = 4.21GRR2561 pKa = 11.84RR2562 pKa = 11.84FVASLFISALATYY2575 pKa = 8.07TYY2577 pKa = 9.07KK2578 pKa = 9.39TWNYY2582 pKa = 8.88HH2583 pKa = 4.73NLSKK2587 pKa = 10.92VVEE2590 pKa = 4.14PALAYY2595 pKa = 10.45LPYY2598 pKa = 9.59ATSALKK2604 pKa = 10.23MFTPTRR2610 pKa = 11.84LEE2612 pKa = 4.09SVVILSTTIYY2622 pKa = 9.06KK2623 pKa = 9.82TYY2625 pKa = 10.94LSIRR2629 pKa = 11.84KK2630 pKa = 8.83GKK2632 pKa = 10.32SDD2634 pKa = 3.4GLLGTGISAAMEE2646 pKa = 4.0ILSQNPVSVGISVMLGVGAIAAHH2669 pKa = 5.76NAIEE2673 pKa = 4.12SSEE2676 pKa = 4.04QKK2678 pKa = 9.15RR2679 pKa = 11.84TLLMKK2684 pKa = 10.23VFVKK2688 pKa = 10.87NFLDD2692 pKa = 3.73QAATDD2697 pKa = 3.92EE2698 pKa = 4.37LVKK2701 pKa = 10.75EE2702 pKa = 4.17NPEE2705 pKa = 4.28KK2706 pKa = 10.47IIMALFEE2713 pKa = 4.24AVQTIGNPLRR2723 pKa = 11.84LIYY2726 pKa = 10.16HH2727 pKa = 7.2LYY2729 pKa = 8.76GVYY2732 pKa = 10.53YY2733 pKa = 10.11KK2734 pKa = 10.76GWEE2737 pKa = 3.92AKK2739 pKa = 9.77EE2740 pKa = 3.87LSEE2743 pKa = 4.17RR2744 pKa = 11.84TAGRR2748 pKa = 11.84NLFTLIMFEE2757 pKa = 4.03AFEE2760 pKa = 4.29LLGMDD2765 pKa = 3.41SQGKK2769 pKa = 8.77IRR2771 pKa = 11.84NLSGNYY2777 pKa = 9.52ILDD2780 pKa = 5.09LIYY2783 pKa = 10.87GLHH2786 pKa = 5.45KK2787 pKa = 10.5QINRR2791 pKa = 11.84GLKK2794 pKa = 10.41KK2795 pKa = 9.75MVLGWAPAPFSCDD2808 pKa = 2.41WTPSDD2813 pKa = 4.09EE2814 pKa = 4.9RR2815 pKa = 11.84IRR2817 pKa = 11.84LPTDD2821 pKa = 2.73NYY2823 pKa = 10.71LRR2825 pKa = 11.84VEE2827 pKa = 4.36TRR2829 pKa = 11.84CPCGYY2834 pKa = 10.42EE2835 pKa = 3.61MKK2837 pKa = 10.55AFKK2840 pKa = 10.78NVGGKK2845 pKa = 7.38LTKK2848 pKa = 10.25VEE2850 pKa = 4.03EE2851 pKa = 4.47SGPFLCRR2858 pKa = 11.84NRR2860 pKa = 11.84PGRR2863 pKa = 11.84GPVNYY2868 pKa = 9.76RR2869 pKa = 11.84VTKK2872 pKa = 10.77YY2873 pKa = 10.84YY2874 pKa = 10.74DD2875 pKa = 3.44DD2876 pKa = 3.87NLRR2879 pKa = 11.84EE2880 pKa = 4.17IKK2882 pKa = 10.17PVAKK2886 pKa = 10.69LEE2888 pKa = 4.26GQVEE2892 pKa = 4.58HH2893 pKa = 6.82YY2894 pKa = 10.35YY2895 pKa = 10.91KK2896 pKa = 10.98GVTAKK2901 pKa = 9.87IDD2903 pKa = 3.59YY2904 pKa = 10.72SKK2906 pKa = 11.58GKK2908 pKa = 8.82MLLATDD2914 pKa = 3.16KK2915 pKa = 10.92WEE2917 pKa = 4.15VEE2919 pKa = 4.0HH2920 pKa = 7.32GVITRR2925 pKa = 11.84LAKK2928 pKa = 10.24RR2929 pKa = 11.84YY2930 pKa = 8.18TGVGFNGAYY2939 pKa = 10.57LGDD2942 pKa = 4.19EE2943 pKa = 4.36PNHH2946 pKa = 6.05RR2947 pKa = 11.84ALVEE2951 pKa = 4.1RR2952 pKa = 11.84DD2953 pKa = 3.14CATITKK2959 pKa = 8.64NTVQFLKK2966 pKa = 9.92MKK2968 pKa = 9.76KK2969 pKa = 9.75GCAFTYY2975 pKa = 10.77DD2976 pKa = 3.71LTISNLTRR2984 pKa = 11.84LIEE2987 pKa = 4.08LVHH2990 pKa = 6.61RR2991 pKa = 11.84NNLEE2995 pKa = 3.95EE2996 pKa = 4.73KK2997 pKa = 9.54EE2998 pKa = 4.23IPTATVTTWLAYY3010 pKa = 9.18TFVNEE3015 pKa = 4.55DD3016 pKa = 3.02VGTIKK3021 pKa = 10.45PVLGEE3026 pKa = 4.05RR3027 pKa = 11.84VIPDD3031 pKa = 3.47PVVDD3035 pKa = 4.3INLQPEE3041 pKa = 4.5VQVDD3045 pKa = 3.69TSEE3048 pKa = 4.03VGITIIGRR3056 pKa = 11.84EE3057 pKa = 3.99TLMTTGVTPVLEE3069 pKa = 4.25KK3070 pKa = 11.01VEE3072 pKa = 4.64PDD3074 pKa = 3.24ASDD3077 pKa = 3.28NQNSVKK3083 pKa = 10.38IGLDD3087 pKa = 3.0EE3088 pKa = 4.64GNYY3091 pKa = 8.99PGPGIQTHH3099 pKa = 5.72TLTEE3103 pKa = 4.66EE3104 pKa = 3.51IHH3106 pKa = 6.37NRR3108 pKa = 11.84DD3109 pKa = 3.39ARR3111 pKa = 11.84PFIMILGSRR3120 pKa = 11.84NSISNRR3126 pKa = 11.84AKK3128 pKa = 8.99TARR3131 pKa = 11.84NINLYY3136 pKa = 9.12TGNDD3140 pKa = 3.2PRR3142 pKa = 11.84EE3143 pKa = 4.1IRR3145 pKa = 11.84DD3146 pKa = 3.37LMAAGRR3152 pKa = 11.84MLVVALRR3159 pKa = 11.84DD3160 pKa = 3.52VDD3162 pKa = 4.14PEE3164 pKa = 4.06LSEE3167 pKa = 4.07MVDD3170 pKa = 3.83FKK3172 pKa = 11.42GTFLDD3177 pKa = 4.4RR3178 pKa = 11.84EE3179 pKa = 4.24ALEE3182 pKa = 4.48ALSLGQPKK3190 pKa = 9.66PKK3192 pKa = 10.06QVTKK3196 pKa = 10.25EE3197 pKa = 3.73AVRR3200 pKa = 11.84NLIEE3204 pKa = 3.96QKK3206 pKa = 10.71KK3207 pKa = 10.47DD3208 pKa = 3.25VEE3210 pKa = 4.26IPNWFASDD3218 pKa = 3.76DD3219 pKa = 3.92PVFLEE3224 pKa = 4.85VALKK3228 pKa = 9.85NDD3230 pKa = 2.94KK3231 pKa = 10.73YY3232 pKa = 11.53YY3233 pKa = 11.26LVGDD3237 pKa = 3.63VGEE3240 pKa = 5.26LKK3242 pKa = 10.8DD3243 pKa = 3.43QAKK3246 pKa = 10.68ALGATDD3252 pKa = 3.05QTRR3255 pKa = 11.84IIKK3258 pKa = 9.81EE3259 pKa = 4.08VGSRR3263 pKa = 11.84TYY3265 pKa = 11.65AMKK3268 pKa = 10.65LSSWFLKK3275 pKa = 10.69ASNKK3279 pKa = 9.54QMSLTPLFEE3288 pKa = 4.57EE3289 pKa = 4.82LLLRR3293 pKa = 11.84CPPATKK3299 pKa = 10.3SNKK3302 pKa = 8.82GHH3304 pKa = 6.29MASAYY3309 pKa = 10.17QLAQGNWEE3317 pKa = 3.88PLGCGVHH3324 pKa = 6.69LGTIPARR3331 pKa = 11.84RR3332 pKa = 11.84VKK3334 pKa = 9.66IHH3336 pKa = 6.99PYY3338 pKa = 9.36EE3339 pKa = 5.22AYY3341 pKa = 10.63LKK3343 pKa = 10.47LKK3345 pKa = 10.72DD3346 pKa = 4.63FIEE3349 pKa = 4.52EE3350 pKa = 4.11EE3351 pKa = 4.16EE3352 pKa = 4.16KK3353 pKa = 10.81KK3354 pKa = 10.51PRR3356 pKa = 11.84VKK3358 pKa = 10.21DD3359 pKa = 3.41TVIRR3363 pKa = 11.84EE3364 pKa = 4.05HH3365 pKa = 6.63NKK3367 pKa = 9.55WILKK3371 pKa = 9.93KK3372 pKa = 10.36IRR3374 pKa = 11.84FQGNLNTKK3382 pKa = 10.2KK3383 pKa = 9.8MLNPGKK3389 pKa = 10.35LSEE3392 pKa = 4.04QLDD3395 pKa = 3.74RR3396 pKa = 11.84EE3397 pKa = 4.33GRR3399 pKa = 11.84KK3400 pKa = 9.69RR3401 pKa = 11.84NIYY3404 pKa = 8.67NHH3406 pKa = 6.29QIGTIMSSAGIRR3418 pKa = 11.84LEE3420 pKa = 3.66KK3421 pKa = 10.74LPIVRR3426 pKa = 11.84AQTDD3430 pKa = 3.31TKK3432 pKa = 10.07TFHH3435 pKa = 6.09EE3436 pKa = 5.1AIRR3439 pKa = 11.84DD3440 pKa = 3.96KK3441 pKa = 10.75IDD3443 pKa = 3.31KK3444 pKa = 10.65SEE3446 pKa = 3.82NRR3448 pKa = 11.84QNPEE3452 pKa = 3.63LHH3454 pKa = 6.53NKK3456 pKa = 9.61LLEE3459 pKa = 4.33IFHH3462 pKa = 6.81TIAQPTLKK3470 pKa = 8.89HH3471 pKa = 5.8TYY3473 pKa = 11.01GEE3475 pKa = 4.56VTWEE3479 pKa = 3.73QLEE3482 pKa = 4.19AGVNRR3487 pKa = 11.84KK3488 pKa = 8.53GAAGFLEE3495 pKa = 4.29KK3496 pKa = 10.87KK3497 pKa = 10.67NIGEE3501 pKa = 4.07VLDD3504 pKa = 4.09SEE3506 pKa = 4.46KK3507 pKa = 10.99HH3508 pKa = 5.47LVEE3511 pKa = 4.37QLVRR3515 pKa = 11.84DD3516 pKa = 4.36LKK3518 pKa = 10.87AGRR3521 pKa = 11.84KK3522 pKa = 7.6IKK3524 pKa = 10.55YY3525 pKa = 9.53YY3526 pKa = 9.35EE3527 pKa = 3.67TAIPKK3532 pKa = 9.65NEE3534 pKa = 3.99KK3535 pKa = 10.09RR3536 pKa = 11.84DD3537 pKa = 4.15VSDD3540 pKa = 3.47DD3541 pKa = 3.29WQAGDD3546 pKa = 3.83LVVEE3550 pKa = 4.15KK3551 pKa = 10.22RR3552 pKa = 11.84PRR3554 pKa = 11.84VIQYY3558 pKa = 9.86PEE3560 pKa = 3.77AKK3562 pKa = 9.03TRR3564 pKa = 11.84LAITKK3569 pKa = 9.68VMYY3572 pKa = 10.46NWVKK3576 pKa = 9.42QQPVVIPGYY3585 pKa = 9.68EE3586 pKa = 4.0GKK3588 pKa = 8.33TPLFNIFDD3596 pKa = 4.19KK3597 pKa = 11.07VRR3599 pKa = 11.84KK3600 pKa = 9.09EE3601 pKa = 3.34WDD3603 pKa = 3.44SFNEE3607 pKa = 3.9PVAVSFDD3614 pKa = 3.36TKK3616 pKa = 11.12AWDD3619 pKa = 3.73TQVTSKK3625 pKa = 10.85DD3626 pKa = 3.33LQLIGEE3632 pKa = 4.19IQKK3635 pKa = 10.83YY3636 pKa = 8.05YY3637 pKa = 10.42YY3638 pKa = 10.05KK3639 pKa = 10.64KK3640 pKa = 9.4EE3641 pKa = 3.45WHH3643 pKa = 6.59KK3644 pKa = 11.08FIDD3647 pKa = 4.45TITDD3651 pKa = 2.84HH3652 pKa = 5.41MTEE3655 pKa = 4.29VPVITADD3662 pKa = 3.48GEE3664 pKa = 4.61VYY3666 pKa = 10.09IRR3668 pKa = 11.84NGQRR3672 pKa = 11.84GSGQPDD3678 pKa = 3.48TSAGNSMLNVLTMMYY3693 pKa = 9.3GFCEE3697 pKa = 4.43STGVPYY3703 pKa = 10.78KK3704 pKa = 10.66SFNRR3708 pKa = 11.84VARR3711 pKa = 11.84IHH3713 pKa = 6.09VCGDD3717 pKa = 3.2DD3718 pKa = 3.59GFLITEE3724 pKa = 4.61KK3725 pKa = 11.12GLGLKK3730 pKa = 9.49FANKK3734 pKa = 9.37GMQILHH3740 pKa = 6.5EE3741 pKa = 4.61AGKK3744 pKa = 8.28PQKK3747 pKa = 9.05ITEE3750 pKa = 4.09GEE3752 pKa = 4.21KK3753 pKa = 9.99MKK3755 pKa = 10.64VAYY3758 pKa = 9.93RR3759 pKa = 11.84FEE3761 pKa = 6.63DD3762 pKa = 3.49IEE3764 pKa = 4.64FCSHH3768 pKa = 5.71TPVPVRR3774 pKa = 11.84WSDD3777 pKa = 3.28NTSSHH3782 pKa = 5.01MAGRR3786 pKa = 11.84DD3787 pKa = 3.24TAVILSKK3794 pKa = 10.27MATRR3798 pKa = 11.84LDD3800 pKa = 3.66SSGEE3804 pKa = 4.1RR3805 pKa = 11.84GTTAYY3810 pKa = 9.28EE3811 pKa = 3.82KK3812 pKa = 10.75AVAFSFLLMYY3822 pKa = 10.28SWNPLVRR3829 pKa = 11.84RR3830 pKa = 11.84ICLLVLSQQPEE3841 pKa = 4.15TDD3843 pKa = 3.59PSKK3846 pKa = 10.75HH3847 pKa = 4.24ATYY3850 pKa = 10.15YY3851 pKa = 10.93YY3852 pKa = 10.67KK3853 pKa = 10.69GDD3855 pKa = 4.37PIGAYY3860 pKa = 9.61KK3861 pKa = 10.53DD3862 pKa = 3.56VIGRR3866 pKa = 11.84NLSEE3870 pKa = 4.29LKK3872 pKa = 9.68RR3873 pKa = 11.84TGFEE3877 pKa = 3.83KK3878 pKa = 10.7LANLNLSLSTLGVWTKK3894 pKa = 9.02HH3895 pKa = 3.65TSKK3898 pKa = 10.81RR3899 pKa = 11.84IIQDD3903 pKa = 3.14CVAIGKK3909 pKa = 9.58EE3910 pKa = 3.89EE3911 pKa = 4.28GNWLVKK3917 pKa = 9.67PDD3919 pKa = 3.96RR3920 pKa = 11.84LISSKK3925 pKa = 9.57TGHH3928 pKa = 7.19LYY3930 pKa = 10.26IPDD3933 pKa = 3.79KK3934 pKa = 11.36GFTLQGKK3941 pKa = 9.3HH3942 pKa = 5.55YY3943 pKa = 9.61EE3944 pKa = 4.06QLQLRR3949 pKa = 11.84TEE3951 pKa = 4.38TNPVMGVGTEE3961 pKa = 4.19RR3962 pKa = 11.84YY3963 pKa = 9.44KK3964 pKa = 11.03LGPIVNLLLRR3974 pKa = 11.84RR3975 pKa = 11.84LKK3977 pKa = 10.31ILLMTAVGVSSS3988 pKa = 3.53

Molecular weight:
449.16 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

3988

3988

3988

3988.0

449.16

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.843 ± 0.0

1.906 ± 0.0

4.514 ± 0.0

6.795 ± 0.0

3.009 ± 0.0

7.523 ± 0.0

2.106 ± 0.0

6.194 ± 0.0

7.447 ± 0.0

9.855 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.482 ± 0.0

3.837 ± 0.0

4.413 ± 0.0

3.26 ± 0.0

5.291 ± 0.0

5.191 ± 0.0

7.146 ± 0.0

7.447 ± 0.0

1.58 ± 0.0

4.162 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski