Amino acid dipepetide frequency for Oidiodendron maius Zn

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.383AlaAla: 8.383 ± 0.05
1.138AlaCys: 1.138 ± 0.014
3.908AlaAsp: 3.908 ± 0.025
4.838AlaGlu: 4.838 ± 0.032
3.277AlaPhe: 3.277 ± 0.023
5.701AlaGly: 5.701 ± 0.036
1.686AlaHis: 1.686 ± 0.016
4.784AlaIle: 4.784 ± 0.03
3.884AlaLys: 3.884 ± 0.03
7.935AlaLeu: 7.935 ± 0.043
1.913AlaMet: 1.913 ± 0.017
2.988AlaAsn: 2.988 ± 0.025
4.082AlaPro: 4.082 ± 0.033
3.118AlaGln: 3.118 ± 0.022
4.455AlaArg: 4.455 ± 0.028
6.818AlaSer: 6.818 ± 0.035
5.195AlaThr: 5.195 ± 0.027
5.279AlaVal: 5.279 ± 0.028
1.228AlaTrp: 1.228 ± 0.015
2.263AlaTyr: 2.263 ± 0.018
0.0AlaXaa: 0.0 ± 0.0
Cys
0.992CysAla: 0.992 ± 0.012
0.292CysCys: 0.292 ± 0.008
0.728CysAsp: 0.728 ± 0.012
0.645CysGlu: 0.645 ± 0.01
0.598CysPhe: 0.598 ± 0.01
1.021CysGly: 1.021 ± 0.013
0.349CysHis: 0.349 ± 0.008
0.88CysIle: 0.88 ± 0.011
0.564CysLys: 0.564 ± 0.01
1.408CysLeu: 1.408 ± 0.017
0.301CysMet: 0.301 ± 0.007
0.492CysAsn: 0.492 ± 0.01
0.667CysPro: 0.667 ± 0.01
0.51CysGln: 0.51 ± 0.01
0.79CysArg: 0.79 ± 0.012
1.076CysSer: 1.076 ± 0.013
0.773CysThr: 0.773 ± 0.011
0.836CysVal: 0.836 ± 0.012
0.24CysTrp: 0.24 ± 0.006
0.419CysTyr: 0.419 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
4.302AspAla: 4.302 ± 0.023
0.676AspCys: 0.676 ± 0.011
3.552AspAsp: 3.552 ± 0.034
3.942AspGlu: 3.942 ± 0.026
2.223AspPhe: 2.223 ± 0.02
4.039AspGly: 4.039 ± 0.027
1.168AspHis: 1.168 ± 0.015
3.555AspIle: 3.555 ± 0.026
2.267AspLys: 2.267 ± 0.019
5.069AspLeu: 5.069 ± 0.03
1.238AspMet: 1.238 ± 0.014
1.958AspAsn: 1.958 ± 0.02
3.125AspPro: 3.125 ± 0.024
1.78AspGln: 1.78 ± 0.016
2.788AspArg: 2.788 ± 0.026
3.966AspSer: 3.966 ± 0.022
2.919AspThr: 2.919 ± 0.02
3.482AspVal: 3.482 ± 0.024
0.91AspTrp: 0.91 ± 0.012
1.613AspTyr: 1.613 ± 0.014
0.0AspXaa: 0.0 ± 0.0
Glu
5.072GluAla: 5.072 ± 0.034
0.69GluCys: 0.69 ± 0.012
3.796GluAsp: 3.796 ± 0.027
4.955GluGlu: 4.955 ± 0.042
2.046GluPhe: 2.046 ± 0.017
3.696GluGly: 3.696 ± 0.026
1.337GluHis: 1.337 ± 0.016
3.404GluIle: 3.404 ± 0.02
3.537GluLys: 3.537 ± 0.03
5.129GluLeu: 5.129 ± 0.03
1.44GluMet: 1.44 ± 0.016
2.399GluAsn: 2.399 ± 0.019
2.392GluPro: 2.392 ± 0.023
2.236GluGln: 2.236 ± 0.019
3.723GluArg: 3.723 ± 0.029
4.166GluSer: 4.166 ± 0.028
3.281GluThr: 3.281 ± 0.021
3.543GluVal: 3.543 ± 0.024
0.937GluTrp: 0.937 ± 0.012
1.746GluTyr: 1.746 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
3.138PheAla: 3.138 ± 0.025
0.621PheCys: 0.621 ± 0.01
2.303PheAsp: 2.303 ± 0.018
2.226PheGlu: 2.226 ± 0.018
1.697PhePhe: 1.697 ± 0.018
2.995PheGly: 2.995 ± 0.022
0.918PheHis: 0.918 ± 0.012
2.138PheIle: 2.138 ± 0.02
1.6PheLys: 1.6 ± 0.016
3.668PheLeu: 3.668 ± 0.027
0.825PheMet: 0.825 ± 0.01
1.572PheAsn: 1.572 ± 0.016
2.012PhePro: 2.012 ± 0.019
1.51PheGln: 1.51 ± 0.015
1.967PheArg: 1.967 ± 0.018
3.242PheSer: 3.242 ± 0.021
2.302PheThr: 2.302 ± 0.018
2.449PheVal: 2.449 ± 0.018
0.73PheTrp: 0.73 ± 0.011
1.228PheTyr: 1.228 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.202GlyAla: 5.202 ± 0.033
0.985GlyCys: 0.985 ± 0.014
3.545GlyAsp: 3.545 ± 0.021
3.586GlyGlu: 3.586 ± 0.026
2.918GlyPhe: 2.918 ± 0.02
5.605GlyGly: 5.605 ± 0.043
1.688GlyHis: 1.688 ± 0.015
4.057GlyIle: 4.057 ± 0.024
3.538GlyLys: 3.538 ± 0.026
6.276GlyLeu: 6.276 ± 0.035
1.648GlyMet: 1.648 ± 0.015
2.717GlyAsn: 2.717 ± 0.021
3.254GlyPro: 3.254 ± 0.025
2.509GlyGln: 2.509 ± 0.017
4.001GlyArg: 4.001 ± 0.024
5.742GlySer: 5.742 ± 0.03
4.163GlyThr: 4.163 ± 0.029
4.449GlyVal: 4.449 ± 0.029
1.257GlyTrp: 1.257 ± 0.013
2.274GlyTyr: 2.274 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
1.74HisAla: 1.74 ± 0.014
0.37HisCys: 0.37 ± 0.007
1.263HisAsp: 1.263 ± 0.013
1.24HisGlu: 1.24 ± 0.014
0.932HisPhe: 0.932 ± 0.011
1.666HisGly: 1.666 ± 0.015
0.742HisHis: 0.742 ± 0.012
1.346HisIle: 1.346 ± 0.015
0.904HisLys: 0.904 ± 0.013
2.259HisLeu: 2.259 ± 0.019
0.497HisMet: 0.497 ± 0.008
0.882HisAsn: 0.882 ± 0.012
1.56HisPro: 1.56 ± 0.015
0.887HisGln: 0.887 ± 0.011
1.414HisArg: 1.414 ± 0.016
1.81HisSer: 1.81 ± 0.015
1.272HisThr: 1.272 ± 0.014
1.353HisVal: 1.353 ± 0.015
0.357HisTrp: 0.357 ± 0.007
0.71HisTyr: 0.71 ± 0.009
0.0HisXaa: 0.0 ± 0.0
Ile
4.622IleAla: 4.622 ± 0.032
0.912IleCys: 0.912 ± 0.012
3.145IleAsp: 3.145 ± 0.023
3.15IleGlu: 3.15 ± 0.021
2.42IlePhe: 2.42 ± 0.022
3.741IleGly: 3.741 ± 0.026
1.306IleHis: 1.306 ± 0.013
3.195IleIle: 3.195 ± 0.023
2.414IleLys: 2.414 ± 0.018
5.352IleLeu: 5.352 ± 0.032
1.168IleMet: 1.168 ± 0.013
2.184IleAsn: 2.184 ± 0.018
3.32IlePro: 3.32 ± 0.025
2.154IleGln: 2.154 ± 0.018
2.973IleArg: 2.973 ± 0.02
4.639IleSer: 4.639 ± 0.027
3.337IleThr: 3.337 ± 0.024
3.557IleVal: 3.557 ± 0.025
0.896IleTrp: 0.896 ± 0.012
1.768IleTyr: 1.768 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
4.027LysAla: 4.027 ± 0.031
0.554LysCys: 0.554 ± 0.01
2.716LysAsp: 2.716 ± 0.024
3.271LysGlu: 3.271 ± 0.027
1.591LysPhe: 1.591 ± 0.016
2.967LysGly: 2.967 ± 0.024
1.072LysHis: 1.072 ± 0.014
2.562LysIle: 2.562 ± 0.02
2.96LysLys: 2.96 ± 0.032
4.194LysLeu: 4.194 ± 0.025
1.032LysMet: 1.032 ± 0.013
1.762LysAsn: 1.762 ± 0.016
2.392LysPro: 2.392 ± 0.02
1.702LysGln: 1.702 ± 0.014
3.174LysArg: 3.174 ± 0.025
3.584LysSer: 3.584 ± 0.022
2.775LysThr: 2.775 ± 0.02
2.852LysVal: 2.852 ± 0.023
0.713LysTrp: 0.713 ± 0.01
1.525LysTyr: 1.525 ± 0.016
0.0LysXaa: 0.0 ± 0.0
Leu
7.893LeuAla: 7.893 ± 0.038
1.353LeuCys: 1.353 ± 0.013
5.245LeuAsp: 5.245 ± 0.028
5.671LeuGlu: 5.671 ± 0.034
3.514LeuPhe: 3.514 ± 0.026
6.33LeuGly: 6.33 ± 0.033
2.321LeuHis: 2.321 ± 0.018
4.517LeuIle: 4.517 ± 0.026
4.333LeuLys: 4.333 ± 0.028
8.92LeuLeu: 8.92 ± 0.051
1.874LeuMet: 1.874 ± 0.019
3.384LeuAsn: 3.384 ± 0.021
5.474LeuPro: 5.474 ± 0.029
4.014LeuGln: 4.014 ± 0.025
5.517LeuArg: 5.517 ± 0.03
7.669LeuSer: 7.669 ± 0.036
4.999LeuThr: 4.999 ± 0.03
5.585LeuVal: 5.585 ± 0.033
1.381LeuTrp: 1.381 ± 0.014
2.674LeuTyr: 2.674 ± 0.024
0.0LeuXaa: 0.0 ± 0.0
Met
2.213MetAla: 2.213 ± 0.015
0.277MetCys: 0.277 ± 0.006
1.201MetAsp: 1.201 ± 0.013
1.271MetGlu: 1.271 ± 0.014
0.784MetPhe: 0.784 ± 0.012
1.445MetGly: 1.445 ± 0.016
0.498MetHis: 0.498 ± 0.008
1.109MetIle: 1.109 ± 0.013
1.051MetLys: 1.051 ± 0.014
1.891MetLeu: 1.891 ± 0.017
0.551MetMet: 0.551 ± 0.01
0.837MetAsn: 0.837 ± 0.011
1.217MetPro: 1.217 ± 0.013
0.845MetGln: 0.845 ± 0.011
1.237MetArg: 1.237 ± 0.011
1.832MetSer: 1.832 ± 0.017
1.298MetThr: 1.298 ± 0.013
1.316MetVal: 1.316 ± 0.014
0.304MetTrp: 0.304 ± 0.007
0.564MetTyr: 0.564 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.136AsnAla: 3.136 ± 0.02
0.528AsnCys: 0.528 ± 0.011
1.933AsnAsp: 1.933 ± 0.018
2.071AsnGlu: 2.071 ± 0.017
1.585AsnPhe: 1.585 ± 0.017
3.115AsnGly: 3.115 ± 0.022
0.859AsnHis: 0.859 ± 0.011
2.51AsnIle: 2.51 ± 0.019
1.531AsnLys: 1.531 ± 0.016
3.609AsnLeu: 3.609 ± 0.025
0.856AsnMet: 0.856 ± 0.011
1.599AsnAsn: 1.599 ± 0.017
2.449AsnPro: 2.449 ± 0.021
1.361AsnGln: 1.361 ± 0.016
1.911AsnArg: 1.911 ± 0.02
3.087AsnSer: 3.087 ± 0.02
2.324AsnThr: 2.324 ± 0.021
2.364AsnVal: 2.364 ± 0.017
0.652AsnTrp: 0.652 ± 0.009
1.209AsnTyr: 1.209 ± 0.016
0.0AsnXaa: 0.0 ± 0.0
Pro
4.509ProAla: 4.509 ± 0.031
0.54ProCys: 0.54 ± 0.01
2.993ProAsp: 2.993 ± 0.023
3.441ProGlu: 3.441 ± 0.026
2.081ProPhe: 2.081 ± 0.019
3.71ProGly: 3.71 ± 0.028
1.215ProHis: 1.215 ± 0.014
2.774ProIle: 2.774 ± 0.021
2.432ProLys: 2.432 ± 0.021
4.772ProLeu: 4.772 ± 0.026
0.977ProMet: 0.977 ± 0.014
2.258ProAsn: 2.258 ± 0.019
4.129ProPro: 4.129 ± 0.036
2.215ProGln: 2.215 ± 0.019
2.993ProArg: 2.993 ± 0.025
5.466ProSer: 5.466 ± 0.035
3.686ProThr: 3.686 ± 0.024
3.267ProVal: 3.267 ± 0.023
0.777ProTrp: 0.777 ± 0.01
1.567ProTyr: 1.567 ± 0.015
0.0ProXaa: 0.0 ± 0.0
Gln
3.223GlnAla: 3.223 ± 0.027
0.507GlnCys: 0.507 ± 0.009
2.016GlnAsp: 2.016 ± 0.017
2.273GlnGlu: 2.273 ± 0.019
1.368GlnPhe: 1.368 ± 0.014
2.398GlnGly: 2.398 ± 0.019
0.955GlnHis: 0.955 ± 0.012
2.11GlnIle: 2.11 ± 0.017
1.923GlnLys: 1.923 ± 0.018
3.491GlnLeu: 3.491 ± 0.024
0.846GlnMet: 0.846 ± 0.012
1.621GlnAsn: 1.621 ± 0.015
2.125GlnPro: 2.125 ± 0.021
1.95GlnGln: 1.95 ± 0.031
2.404GlnArg: 2.404 ± 0.022
3.031GlnSer: 3.031 ± 0.023
2.27GlnThr: 2.27 ± 0.018
2.19GlnVal: 2.19 ± 0.018
0.618GlnTrp: 0.618 ± 0.01
1.252GlnTyr: 1.252 ± 0.013
0.0GlnXaa: 0.0 ± 0.0
Arg
4.31ArgAla: 4.31 ± 0.032
0.75ArgCys: 0.75 ± 0.011
3.19ArgAsp: 3.19 ± 0.026
3.626ArgGlu: 3.626 ± 0.03
2.041ArgPhe: 2.041 ± 0.014
3.571ArgGly: 3.571 ± 0.026
1.459ArgHis: 1.459 ± 0.015
3.068ArgIle: 3.068 ± 0.021
3.219ArgLys: 3.219 ± 0.024
5.395ArgLeu: 5.395 ± 0.034
1.247ArgMet: 1.247 ± 0.013
2.218ArgAsn: 2.218 ± 0.02
3.065ArgPro: 3.065 ± 0.025
2.411ArgGln: 2.411 ± 0.018
4.417ArgArg: 4.417 ± 0.036
4.343ArgSer: 4.343 ± 0.034
3.071ArgThr: 3.071 ± 0.023
3.207ArgVal: 3.207 ± 0.02
0.939ArgTrp: 0.939 ± 0.011
1.694ArgTyr: 1.694 ± 0.017
0.0ArgXaa: 0.0 ± 0.0
Ser
6.311SerAla: 6.311 ± 0.034
1.027SerCys: 1.027 ± 0.014
4.042SerAsp: 4.042 ± 0.024
4.005SerGlu: 4.005 ± 0.027
3.174SerPhe: 3.174 ± 0.024
5.699SerGly: 5.699 ± 0.03
1.887SerHis: 1.887 ± 0.019
4.661SerIle: 4.661 ± 0.024
3.765SerLys: 3.765 ± 0.023
7.556SerLeu: 7.556 ± 0.033
1.771SerMet: 1.771 ± 0.018
3.247SerAsn: 3.247 ± 0.022
5.047SerPro: 5.047 ± 0.042
3.226SerGln: 3.226 ± 0.022
4.661SerArg: 4.661 ± 0.034
8.414SerSer: 8.414 ± 0.062
5.63SerThr: 5.63 ± 0.036
4.613SerVal: 4.613 ± 0.029
1.299SerTrp: 1.299 ± 0.014
2.297SerTyr: 2.297 ± 0.018
0.0SerXaa: 0.0 ± 0.0
Thr
5.159ThrAla: 5.159 ± 0.03
0.81ThrCys: 0.81 ± 0.012
2.789ThrAsp: 2.789 ± 0.021
3.014ThrGlu: 3.014 ± 0.022
2.451ThrPhe: 2.451 ± 0.021
4.286ThrGly: 4.286 ± 0.026
1.23ThrHis: 1.23 ± 0.013
3.557ThrIle: 3.557 ± 0.023
2.576ThrLys: 2.576 ± 0.021
5.547ThrLeu: 5.547 ± 0.036
1.18ThrMet: 1.18 ± 0.013
2.257ThrAsn: 2.257 ± 0.021
3.886ThrPro: 3.886 ± 0.03
2.016ThrGln: 2.016 ± 0.018
2.945ThrArg: 2.945 ± 0.021
5.399ThrSer: 5.399 ± 0.032
4.293ThrThr: 4.293 ± 0.044
3.809ThrVal: 3.809 ± 0.022
0.95ThrTrp: 0.95 ± 0.012
1.822ThrTyr: 1.822 ± 0.017
0.0ThrXaa: 0.0 ± 0.0
Val
5.155ValAla: 5.155 ± 0.031
0.848ValCys: 0.848 ± 0.013
3.562ValAsp: 3.562 ± 0.023
3.768ValGlu: 3.768 ± 0.029
2.493ValPhe: 2.493 ± 0.02
4.126ValGly: 4.126 ± 0.029
1.346ValHis: 1.346 ± 0.015
3.354ValIle: 3.354 ± 0.025
2.855ValLys: 2.855 ± 0.023
5.788ValLeu: 5.788 ± 0.03
1.332ValMet: 1.332 ± 0.013
2.308ValAsn: 2.308 ± 0.02
3.354ValPro: 3.354 ± 0.021
2.332ValGln: 2.332 ± 0.017
3.263ValArg: 3.263 ± 0.024
4.61ValSer: 4.61 ± 0.026
3.588ValThr: 3.588 ± 0.026
4.233ValVal: 4.233 ± 0.026
0.925ValTrp: 0.925 ± 0.012
1.835ValTyr: 1.835 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.235TrpAla: 1.235 ± 0.014
0.22TrpCys: 0.22 ± 0.006
0.975TrpAsp: 0.975 ± 0.013
0.915TrpGlu: 0.915 ± 0.012
0.593TrpPhe: 0.593 ± 0.009
1.046TrpGly: 1.046 ± 0.014
0.379TrpHis: 0.379 ± 0.007
0.941TrpIle: 0.941 ± 0.014
0.85TrpLys: 0.85 ± 0.012
1.465TrpLeu: 1.465 ± 0.016
0.398TrpMet: 0.398 ± 0.008
0.713TrpAsn: 0.713 ± 0.011
0.669TrpPro: 0.669 ± 0.009
0.613TrpGln: 0.613 ± 0.009
0.954TrpArg: 0.954 ± 0.011
1.153TrpSer: 1.153 ± 0.014
1.023TrpThr: 1.023 ± 0.013
0.986TrpVal: 0.986 ± 0.012
0.316TrpTrp: 0.316 ± 0.008
0.494TrpTyr: 0.494 ± 0.008
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.251TyrAla: 2.251 ± 0.019
0.484TyrCys: 0.484 ± 0.009
1.671TyrAsp: 1.671 ± 0.015
1.619TyrGlu: 1.619 ± 0.015
1.354TyrPhe: 1.354 ± 0.014
2.255TyrGly: 2.255 ± 0.019
0.788TyrHis: 0.788 ± 0.012
1.73TyrIle: 1.73 ± 0.017
1.221TyrLys: 1.221 ± 0.013
2.944TyrLeu: 2.944 ± 0.022
0.646TyrMet: 0.646 ± 0.009
1.295TyrAsn: 1.295 ± 0.014
1.583TyrPro: 1.583 ± 0.016
1.183TyrGln: 1.183 ± 0.015
1.655TyrArg: 1.655 ± 0.016
2.283TyrSer: 2.283 ± 0.019
1.776TyrThr: 1.776 ± 0.015
1.704TyrVal: 1.704 ± 0.016
0.507TyrTrp: 0.507 ± 0.009
1.035TyrTyr: 1.035 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 16697 proteins (7153503 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski