Amino acid dipepetide frequency for Trichoplusia ni ascovirus 2c (TnAV-2c)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.163AlaAla: 2.163 ± 0.266
1.061AlaCys: 1.061 ± 0.156
1.633AlaAsp: 1.633 ± 0.149
1.857AlaGlu: 1.857 ± 0.168
1.755AlaPhe: 1.755 ± 0.193
2.082AlaGly: 2.082 ± 0.289
0.837AlaHis: 0.837 ± 0.131
3.306AlaIle: 3.306 ± 0.266
2.449AlaLys: 2.449 ± 0.238
4.163AlaLeu: 4.163 ± 0.266
1.347AlaMet: 1.347 ± 0.116
2.633AlaAsn: 2.633 ± 0.241
1.061AlaPro: 1.061 ± 0.161
1.184AlaGln: 1.184 ± 0.167
2.143AlaArg: 2.143 ± 0.285
3.775AlaSer: 3.775 ± 0.295
2.857AlaThr: 2.857 ± 0.275
2.837AlaVal: 2.837 ± 0.266
0.571AlaTrp: 0.571 ± 0.124
1.837AlaTyr: 1.837 ± 0.223
0.0AlaXaa: 0.0 ± 0.0
Cys
1.143CysAla: 1.143 ± 0.152
0.673CysCys: 0.673 ± 0.126
1.877CysAsp: 1.877 ± 0.222
1.429CysGlu: 1.429 ± 0.178
0.714CysPhe: 0.714 ± 0.123
1.469CysGly: 1.469 ± 0.172
0.388CysHis: 0.388 ± 0.088
2.02CysIle: 2.02 ± 0.186
1.816CysLys: 1.816 ± 0.241
1.714CysLeu: 1.714 ± 0.214
0.837CysMet: 0.837 ± 0.133
2.041CysAsn: 2.041 ± 0.237
0.714CysPro: 0.714 ± 0.111
0.694CysGln: 0.694 ± 0.109
1.49CysArg: 1.49 ± 0.205
1.898CysSer: 1.898 ± 0.224
1.265CysThr: 1.265 ± 0.143
1.694CysVal: 1.694 ± 0.192
0.163CysTrp: 0.163 ± 0.055
0.898CysTyr: 0.898 ± 0.178
0.0CysXaa: 0.0 ± 0.0
Asp
2.571AspAla: 2.571 ± 0.221
1.326AspCys: 1.326 ± 0.173
9.877AspAsp: 9.877 ± 0.861
4.714AspGlu: 4.714 ± 0.34
2.102AspPhe: 2.102 ± 0.21
3.286AspGly: 3.286 ± 0.231
1.347AspHis: 1.347 ± 0.161
5.551AspIle: 5.551 ± 0.277
3.653AspLys: 3.653 ± 0.23
4.204AspLeu: 4.204 ± 0.287
1.714AspMet: 1.714 ± 0.154
5.204AspAsn: 5.204 ± 0.359
1.592AspPro: 1.592 ± 0.21
1.143AspGln: 1.143 ± 0.16
2.286AspArg: 2.286 ± 0.195
3.775AspSer: 3.775 ± 0.283
3.612AspThr: 3.612 ± 0.228
4.388AspVal: 4.388 ± 0.294
0.775AspTrp: 0.775 ± 0.132
2.979AspTyr: 2.979 ± 0.241
0.0AspXaa: 0.0 ± 0.0
Glu
2.306GluAla: 2.306 ± 0.235
1.469GluCys: 1.469 ± 0.203
4.122GluAsp: 4.122 ± 0.285
3.653GluGlu: 3.653 ± 0.352
1.959GluPhe: 1.959 ± 0.217
1.673GluGly: 1.673 ± 0.183
1.224GluHis: 1.224 ± 0.156
4.184GluIle: 4.184 ± 0.329
3.326GluLys: 3.326 ± 0.363
5.571GluLeu: 5.571 ± 0.552
1.184GluMet: 1.184 ± 0.138
4.673GluAsn: 4.673 ± 0.43
1.122GluPro: 1.122 ± 0.144
1.592GluGln: 1.592 ± 0.151
2.388GluArg: 2.388 ± 0.306
3.428GluSer: 3.428 ± 0.297
3.0GluThr: 3.0 ± 0.248
2.653GluVal: 2.653 ± 0.204
0.551GluTrp: 0.551 ± 0.101
2.633GluTyr: 2.633 ± 0.247
0.0GluXaa: 0.0 ± 0.0
Phe
1.714PheAla: 1.714 ± 0.197
1.122PheCys: 1.122 ± 0.161
2.775PheAsp: 2.775 ± 0.239
1.898PheGlu: 1.898 ± 0.23
1.245PhePhe: 1.245 ± 0.174
1.51PheGly: 1.51 ± 0.174
0.918PheHis: 0.918 ± 0.127
3.061PheIle: 3.061 ± 0.241
3.143PheLys: 3.143 ± 0.244
2.714PheLeu: 2.714 ± 0.247
0.878PheMet: 0.878 ± 0.144
2.653PheAsn: 2.653 ± 0.256
1.163PhePro: 1.163 ± 0.148
1.082PheGln: 1.082 ± 0.156
1.612PheArg: 1.612 ± 0.21
2.265PheSer: 2.265 ± 0.199
2.408PheThr: 2.408 ± 0.215
2.265PheVal: 2.265 ± 0.22
0.347PheTrp: 0.347 ± 0.091
1.449PheTyr: 1.449 ± 0.213
0.0PheXaa: 0.0 ± 0.0
Gly
2.633GlyAla: 2.633 ± 0.349
0.816GlyCys: 0.816 ± 0.12
3.49GlyAsp: 3.49 ± 0.294
2.245GlyGlu: 2.245 ± 0.214
1.694GlyPhe: 1.694 ± 0.199
2.816GlyGly: 2.816 ± 0.296
0.857GlyHis: 0.857 ± 0.157
3.408GlyIle: 3.408 ± 0.28
2.673GlyLys: 2.673 ± 0.221
2.898GlyLeu: 2.898 ± 0.324
1.041GlyMet: 1.041 ± 0.144
2.326GlyAsn: 2.326 ± 0.212
1.082GlyPro: 1.082 ± 0.156
0.98GlyGln: 0.98 ± 0.141
1.918GlyArg: 1.918 ± 0.217
3.102GlySer: 3.102 ± 0.332
2.306GlyThr: 2.306 ± 0.279
3.163GlyVal: 3.163 ± 0.255
0.51GlyTrp: 0.51 ± 0.106
1.633GlyTyr: 1.633 ± 0.182
0.0GlyXaa: 0.0 ± 0.0
His
1.0HisAla: 1.0 ± 0.151
0.449HisCys: 0.449 ± 0.093
1.49HisAsp: 1.49 ± 0.154
1.306HisGlu: 1.306 ± 0.197
0.775HisPhe: 0.775 ± 0.121
1.347HisGly: 1.347 ± 0.165
1.082HisHis: 1.082 ± 0.158
1.49HisIle: 1.49 ± 0.176
1.653HisLys: 1.653 ± 0.189
1.714HisLeu: 1.714 ± 0.166
0.633HisMet: 0.633 ± 0.097
1.816HisAsn: 1.816 ± 0.181
0.571HisPro: 0.571 ± 0.088
1.061HisGln: 1.061 ± 0.161
1.367HisArg: 1.367 ± 0.153
1.347HisSer: 1.347 ± 0.158
1.265HisThr: 1.265 ± 0.127
1.714HisVal: 1.714 ± 0.165
0.204HisTrp: 0.204 ± 0.055
1.0HisTyr: 1.0 ± 0.12
0.0HisXaa: 0.0 ± 0.0
Ile
3.02IleAla: 3.02 ± 0.303
1.857IleCys: 1.857 ± 0.201
5.163IleAsp: 5.163 ± 0.289
4.041IleGlu: 4.041 ± 0.332
2.469IlePhe: 2.469 ± 0.228
3.204IleGly: 3.204 ± 0.331
1.98IleHis: 1.98 ± 0.2
7.061IleIle: 7.061 ± 0.39
5.49IleLys: 5.49 ± 0.326
6.347IleLeu: 6.347 ± 0.414
2.326IleMet: 2.326 ± 0.244
6.265IleAsn: 6.265 ± 0.316
4.0IlePro: 4.0 ± 0.303
2.326IleGln: 2.326 ± 0.224
3.796IleArg: 3.796 ± 0.29
6.041IleSer: 6.041 ± 0.364
5.122IleThr: 5.122 ± 0.379
5.02IleVal: 5.02 ± 0.36
0.551IleTrp: 0.551 ± 0.136
3.082IleTyr: 3.082 ± 0.285
0.0IleXaa: 0.0 ± 0.0
Lys
2.163LysAla: 2.163 ± 0.221
1.939LysCys: 1.939 ± 0.211
3.53LysAsp: 3.53 ± 0.242
3.367LysGlu: 3.367 ± 0.261
3.0LysPhe: 3.0 ± 0.252
1.51LysGly: 1.51 ± 0.184
1.531LysHis: 1.531 ± 0.182
5.49LysIle: 5.49 ± 0.244
5.877LysLys: 5.877 ± 0.419
6.592LysLeu: 6.592 ± 0.416
1.592LysMet: 1.592 ± 0.208
5.061LysAsn: 5.061 ± 0.342
2.041LysPro: 2.041 ± 0.192
2.612LysGln: 2.612 ± 0.229
4.428LysArg: 4.428 ± 0.324
5.51LysSer: 5.51 ± 0.375
4.306LysThr: 4.306 ± 0.257
3.265LysVal: 3.265 ± 0.303
0.755LysTrp: 0.755 ± 0.115
4.02LysTyr: 4.02 ± 0.244
0.0LysXaa: 0.0 ± 0.0
Leu
3.265LeuAla: 3.265 ± 0.282
2.184LeuCys: 2.184 ± 0.222
4.061LeuAsp: 4.061 ± 0.336
4.041LeuGlu: 4.041 ± 0.464
3.102LeuPhe: 3.102 ± 0.258
2.633LeuGly: 2.633 ± 0.261
2.326LeuHis: 2.326 ± 0.237
5.285LeuIle: 5.285 ± 0.34
6.326LeuLys: 6.326 ± 0.41
7.796LeuLeu: 7.796 ± 0.386
2.571LeuMet: 2.571 ± 0.252
6.449LeuAsn: 6.449 ± 0.538
3.877LeuPro: 3.877 ± 0.32
3.204LeuGln: 3.204 ± 0.327
4.796LeuArg: 4.796 ± 0.329
6.734LeuSer: 6.734 ± 0.349
4.449LeuThr: 4.449 ± 0.264
4.755LeuVal: 4.755 ± 0.364
0.653LeuTrp: 0.653 ± 0.113
3.694LeuTyr: 3.694 ± 0.278
0.0LeuXaa: 0.0 ± 0.0
Met
1.429MetAla: 1.429 ± 0.175
0.939MetCys: 0.939 ± 0.176
1.408MetAsp: 1.408 ± 0.184
1.694MetGlu: 1.694 ± 0.196
1.082MetPhe: 1.082 ± 0.178
0.837MetGly: 0.837 ± 0.128
0.592MetHis: 0.592 ± 0.116
2.061MetIle: 2.061 ± 0.208
2.306MetLys: 2.306 ± 0.203
2.122MetLeu: 2.122 ± 0.194
1.347MetMet: 1.347 ± 0.193
2.367MetAsn: 2.367 ± 0.221
0.612MetPro: 0.612 ± 0.113
0.755MetGln: 0.755 ± 0.137
1.469MetArg: 1.469 ± 0.184
2.367MetSer: 2.367 ± 0.191
1.653MetThr: 1.653 ± 0.185
2.224MetVal: 2.224 ± 0.204
0.245MetTrp: 0.245 ± 0.081
1.571MetTyr: 1.571 ± 0.175
0.0MetXaa: 0.0 ± 0.0
Asn
2.979AsnAla: 2.979 ± 0.227
1.531AsnCys: 1.531 ± 0.168
5.673AsnAsp: 5.673 ± 0.428
4.49AsnGlu: 4.49 ± 0.432
2.592AsnPhe: 2.592 ± 0.217
4.02AsnGly: 4.02 ± 0.325
1.571AsnHis: 1.571 ± 0.174
6.857AsnIle: 6.857 ± 0.377
4.735AsnLys: 4.735 ± 0.35
5.183AsnLeu: 5.183 ± 0.346
2.204AsnMet: 2.204 ± 0.195
7.122AsnAsn: 7.122 ± 0.516
2.143AsnPro: 2.143 ± 0.225
1.408AsnGln: 1.408 ± 0.189
3.653AsnArg: 3.653 ± 0.299
6.163AsnSer: 6.163 ± 0.4
4.775AsnThr: 4.775 ± 0.312
4.816AsnVal: 4.816 ± 0.35
0.347AsnTrp: 0.347 ± 0.073
3.959AsnTyr: 3.959 ± 0.274
0.0AsnXaa: 0.0 ± 0.0
Pro
1.429ProAla: 1.429 ± 0.285
1.0ProCys: 1.0 ± 0.176
1.918ProAsp: 1.918 ± 0.193
1.429ProGlu: 1.429 ± 0.147
1.143ProPhe: 1.143 ± 0.139
1.102ProGly: 1.102 ± 0.184
0.959ProHis: 0.959 ± 0.144
2.449ProIle: 2.449 ± 0.263
2.408ProLys: 2.408 ± 0.194
3.551ProLeu: 3.551 ± 0.278
1.49ProMet: 1.49 ± 0.244
2.082ProAsn: 2.082 ± 0.229
2.143ProPro: 2.143 ± 0.287
1.367ProGln: 1.367 ± 0.235
1.877ProArg: 1.877 ± 0.231
3.326ProSer: 3.326 ± 0.387
2.367ProThr: 2.367 ± 0.242
1.816ProVal: 1.816 ± 0.193
0.367ProTrp: 0.367 ± 0.091
1.449ProTyr: 1.449 ± 0.176
0.0ProXaa: 0.0 ± 0.0
Gln
0.98GlnAla: 0.98 ± 0.131
1.143GlnCys: 1.143 ± 0.15
1.061GlnAsp: 1.061 ± 0.162
1.51GlnGlu: 1.51 ± 0.2
1.0GlnPhe: 1.0 ± 0.145
0.775GlnGly: 0.775 ± 0.118
0.939GlnHis: 0.939 ± 0.135
2.408GlnIle: 2.408 ± 0.273
1.796GlnLys: 1.796 ± 0.185
2.959GlnLeu: 2.959 ± 0.337
0.857GlnMet: 0.857 ± 0.131
2.143GlnAsn: 2.143 ± 0.277
1.326GlnPro: 1.326 ± 0.223
1.837GlnGln: 1.837 ± 0.374
1.633GlnArg: 1.633 ± 0.174
2.184GlnSer: 2.184 ± 0.194
1.49GlnThr: 1.49 ± 0.205
1.449GlnVal: 1.449 ± 0.18
0.367GlnTrp: 0.367 ± 0.086
1.796GlnTyr: 1.796 ± 0.175
0.0GlnXaa: 0.0 ± 0.0
Arg
1.877ArgAla: 1.877 ± 0.191
1.265ArgCys: 1.265 ± 0.181
3.224ArgAsp: 3.224 ± 0.295
2.571ArgGlu: 2.571 ± 0.252
1.959ArgPhe: 1.959 ± 0.178
2.204ArgGly: 2.204 ± 0.237
1.163ArgHis: 1.163 ± 0.142
4.02ArgIle: 4.02 ± 0.243
3.061ArgLys: 3.061 ± 0.305
4.53ArgLeu: 4.53 ± 0.329
1.551ArgMet: 1.551 ± 0.188
3.939ArgAsn: 3.939 ± 0.287
1.612ArgPro: 1.612 ± 0.198
1.653ArgGln: 1.653 ± 0.189
4.367ArgArg: 4.367 ± 0.639
5.408ArgSer: 5.408 ± 1.409
2.531ArgThr: 2.531 ± 0.234
2.837ArgVal: 2.837 ± 0.225
0.429ArgTrp: 0.429 ± 0.082
2.592ArgTyr: 2.592 ± 0.378
0.0ArgXaa: 0.0 ± 0.0
Ser
3.122SerAla: 3.122 ± 0.307
1.735SerCys: 1.735 ± 0.218
4.735SerAsp: 4.735 ± 0.329
4.02SerGlu: 4.02 ± 0.301
2.449SerPhe: 2.449 ± 0.234
3.388SerGly: 3.388 ± 0.288
1.653SerHis: 1.653 ± 0.154
6.163SerIle: 6.163 ± 0.36
5.041SerLys: 5.041 ± 0.375
5.918SerLeu: 5.918 ± 0.376
1.877SerMet: 1.877 ± 0.177
5.714SerAsn: 5.714 ± 0.328
4.041SerPro: 4.041 ± 0.677
1.918SerGln: 1.918 ± 0.24
5.0SerArg: 5.0 ± 1.005
12.04SerSer: 12.04 ± 1.086
5.347SerThr: 5.347 ± 0.352
4.979SerVal: 4.979 ± 0.338
0.633SerTrp: 0.633 ± 0.095
2.755SerTyr: 2.755 ± 0.239
0.0SerXaa: 0.0 ± 0.0
Thr
2.735ThrAla: 2.735 ± 0.24
1.286ThrCys: 1.286 ± 0.155
2.694ThrAsp: 2.694 ± 0.19
2.347ThrGlu: 2.347 ± 0.182
2.347ThrPhe: 2.347 ± 0.199
2.469ThrGly: 2.469 ± 0.244
1.224ThrHis: 1.224 ± 0.163
5.285ThrIle: 5.285 ± 0.338
4.449ThrLys: 4.449 ± 0.287
5.53ThrLeu: 5.53 ± 0.312
2.184ThrMet: 2.184 ± 0.205
4.428ThrAsn: 4.428 ± 0.329
2.755ThrPro: 2.755 ± 0.281
1.755ThrGln: 1.755 ± 0.209
2.939ThrArg: 2.939 ± 0.324
4.857ThrSer: 4.857 ± 0.312
5.469ThrThr: 5.469 ± 0.41
3.979ThrVal: 3.979 ± 0.304
0.469ThrTrp: 0.469 ± 0.1
2.51ThrTyr: 2.51 ± 0.235
0.0ThrXaa: 0.0 ± 0.0
Val
2.735ValAla: 2.735 ± 0.224
1.592ValCys: 1.592 ± 0.185
3.612ValAsp: 3.612 ± 0.273
3.163ValGlu: 3.163 ± 0.271
2.551ValPhe: 2.551 ± 0.198
2.837ValGly: 2.837 ± 0.314
1.429ValHis: 1.429 ± 0.167
5.183ValIle: 5.183 ± 0.38
4.551ValLys: 4.551 ± 0.334
4.837ValLeu: 4.837 ± 0.37
1.775ValMet: 1.775 ± 0.159
4.612ValAsn: 4.612 ± 0.295
1.796ValPro: 1.796 ± 0.185
1.633ValGln: 1.633 ± 0.141
2.673ValArg: 2.673 ± 0.284
4.326ValSer: 4.326 ± 0.314
4.061ValThr: 4.061 ± 0.359
4.551ValVal: 4.551 ± 0.372
0.612ValTrp: 0.612 ± 0.12
2.612ValTyr: 2.612 ± 0.267
0.0ValXaa: 0.0 ± 0.0
Trp
0.327TrpAla: 0.327 ± 0.077
0.347TrpCys: 0.347 ± 0.064
0.408TrpAsp: 0.408 ± 0.098
0.224TrpGlu: 0.224 ± 0.066
0.469TrpPhe: 0.469 ± 0.1
0.367TrpGly: 0.367 ± 0.108
0.143TrpHis: 0.143 ± 0.045
0.633TrpIle: 0.633 ± 0.103
0.673TrpLys: 0.673 ± 0.142
0.796TrpLeu: 0.796 ± 0.144
0.367TrpMet: 0.367 ± 0.087
0.755TrpAsn: 0.755 ± 0.147
0.204TrpPro: 0.204 ± 0.069
0.204TrpGln: 0.204 ± 0.068
0.551TrpArg: 0.551 ± 0.099
0.694TrpSer: 0.694 ± 0.124
0.551TrpThr: 0.551 ± 0.119
0.429TrpVal: 0.429 ± 0.089
0.327TrpTrp: 0.327 ± 0.087
0.694TrpTyr: 0.694 ± 0.109
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.959TyrAla: 1.959 ± 0.194
1.204TyrCys: 1.204 ± 0.199
3.347TyrAsp: 3.347 ± 0.268
2.714TyrGlu: 2.714 ± 0.222
1.816TyrPhe: 1.816 ± 0.19
2.061TyrGly: 2.061 ± 0.209
1.122TyrHis: 1.122 ± 0.154
3.245TyrIle: 3.245 ± 0.288
3.163TyrLys: 3.163 ± 0.242
3.082TyrLeu: 3.082 ± 0.249
1.286TyrMet: 1.286 ± 0.155
3.939TyrAsn: 3.939 ± 0.261
1.816TyrPro: 1.816 ± 0.248
1.245TyrGln: 1.245 ± 0.152
2.408TyrArg: 2.408 ± 0.214
3.286TyrSer: 3.286 ± 0.361
2.877TyrThr: 2.877 ± 0.285
2.306TyrVal: 2.306 ± 0.221
0.286TyrTrp: 0.286 ± 0.093
2.531TyrTyr: 2.531 ± 0.35
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 161 proteins (49003 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski