Amino acid dipepetide frequency for Candidatus Cryosericum terrychapinii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.171AlaAla: 10.171 ± 0.175	1.164AlaCys: 1.164 ± 0.057	5.072AlaAsp: 5.072 ± 0.112	5.295AlaGlu: 5.295 ± 0.127	3.61AlaPhe: 3.61 ± 0.101	8.529AlaGly: 8.529 ± 0.145	1.962AlaHis: 1.962 ± 0.067	5.435AlaIle: 5.435 ± 0.123	3.66AlaLys: 3.66 ± 0.102	10.261AlaLeu: 10.261 ± 0.135	2.743AlaMet: 2.743 ± 0.078	2.507AlaAsn: 2.507 ± 0.098	3.586AlaPro: 3.586 ± 0.107	3.153AlaGln: 3.153 ± 0.082	6.171AlaArg: 6.171 ± 0.136	6.034AlaSer: 6.034 ± 0.127	5.822AlaThr: 5.822 ± 0.148	8.333AlaVal: 8.333 ± 0.159	1.011AlaTrp: 1.011 ± 0.054	2.516AlaTyr: 2.516 ± 0.07	0.0AlaXaa: 0.0 ± 0.0
Cys	0.887CysAla: 0.887 ± 0.052	0.173CysCys: 0.173 ± 0.02	0.644CysAsp: 0.644 ± 0.039	0.504CysGlu: 0.504 ± 0.032	0.351CysPhe: 0.351 ± 0.025	1.092CysGly: 1.092 ± 0.065	0.248CysHis: 0.248 ± 0.023	0.556CysIle: 0.556 ± 0.041	0.318CysLys: 0.318 ± 0.029	0.917CysLeu: 0.917 ± 0.049	0.266CysMet: 0.266 ± 0.025	0.286CysAsn: 0.286 ± 0.026	0.687CysPro: 0.687 ± 0.049	0.284CysGln: 0.284 ± 0.028	0.667CysArg: 0.667 ± 0.04	0.75CysSer: 0.75 ± 0.041	0.705CysThr: 0.705 ± 0.046	0.775CysVal: 0.775 ± 0.043	0.126CysTrp: 0.126 ± 0.018	0.268CysTyr: 0.268 ± 0.028	0.0CysXaa: 0.0 ± 0.0
Asp	5.293AspAla: 5.293 ± 0.111	0.509AspCys: 0.509 ± 0.037	2.613AspAsp: 2.613 ± 0.085	3.448AspGlu: 3.448 ± 0.101	2.056AspPhe: 2.056 ± 0.073	4.423AspGly: 4.423 ± 0.102	1.097AspHis: 1.097 ± 0.052	3.356AspIle: 3.356 ± 0.088	2.252AspLys: 2.252 ± 0.09	5.585AspLeu: 5.585 ± 0.102	1.421AspMet: 1.421 ± 0.061	1.484AspAsn: 1.484 ± 0.061	2.813AspPro: 2.813 ± 0.075	1.754AspGln: 1.754 ± 0.06	3.32AspArg: 3.32 ± 0.097	2.761AspSer: 2.761 ± 0.074	3.092AspThr: 3.092 ± 0.096	4.948AspVal: 4.948 ± 0.101	0.664AspTrp: 0.664 ± 0.034	1.64AspTyr: 1.64 ± 0.062	0.0AspXaa: 0.0 ± 0.0
Glu	5.626GluAla: 5.626 ± 0.14	0.504GluCys: 0.504 ± 0.041	2.811GluAsp: 2.811 ± 0.098	4.124GluGlu: 4.124 ± 0.133	1.919GluPhe: 1.919 ± 0.069	4.137GluGly: 4.137 ± 0.093	1.446GluHis: 1.446 ± 0.067	3.198GluIle: 3.198 ± 0.095	2.745GluLys: 2.745 ± 0.093	6.034GluLeu: 6.034 ± 0.129	1.491GluMet: 1.491 ± 0.054	1.804GluAsn: 1.804 ± 0.074	2.227GluPro: 2.227 ± 0.082	2.466GluGln: 2.466 ± 0.082	4.164GluArg: 4.164 ± 0.115	3.151GluSer: 3.151 ± 0.084	3.286GluThr: 3.286 ± 0.071	4.52GluVal: 4.52 ± 0.115	0.523GluTrp: 0.523 ± 0.037	1.498GluTyr: 1.498 ± 0.069	0.0GluXaa: 0.0 ± 0.0
Phe	3.568PheAla: 3.568 ± 0.089	0.446PheCys: 0.446 ± 0.031	2.286PheAsp: 2.286 ± 0.072	2.068PheGlu: 2.068 ± 0.066	1.556PhePhe: 1.556 ± 0.063	3.39PheGly: 3.39 ± 0.087	0.739PheHis: 0.739 ± 0.039	2.038PheIle: 2.038 ± 0.072	1.259PheLys: 1.259 ± 0.061	3.75PheLeu: 3.75 ± 0.098	0.923PheMet: 0.923 ± 0.051	1.072PheAsn: 1.072 ± 0.049	1.617PhePro: 1.617 ± 0.062	1.043PheGln: 1.043 ± 0.046	1.95PheArg: 1.95 ± 0.067	2.54PheSer: 2.54 ± 0.082	2.227PheThr: 2.227 ± 0.075	3.529PheVal: 3.529 ± 0.111	0.459PheTrp: 0.459 ± 0.037	0.984PheTyr: 0.984 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	7.14GlyAla: 7.14 ± 0.14	0.991GlyCys: 0.991 ± 0.062	4.158GlyAsp: 4.158 ± 0.092	4.067GlyGlu: 4.067 ± 0.11	3.281GlyPhe: 3.281 ± 0.077	6.313GlyGly: 6.313 ± 0.167	1.73GlyHis: 1.73 ± 0.061	5.552GlyIle: 5.552 ± 0.131	4.182GlyLys: 4.182 ± 0.118	8.212GlyLeu: 8.212 ± 0.134	2.349GlyMet: 2.349 ± 0.081	2.304GlyAsn: 2.304 ± 0.085	2.561GlyPro: 2.561 ± 0.08	2.435GlyGln: 2.435 ± 0.081	4.57GlyArg: 4.57 ± 0.101	5.441GlySer: 5.441 ± 0.137	5.786GlyThr: 5.786 ± 0.152	6.678GlyVal: 6.678 ± 0.129	1.061GlyTrp: 1.061 ± 0.054	2.599GlyTyr: 2.599 ± 0.087	0.0GlyXaa: 0.0 ± 0.0
His	1.887HisAla: 1.887 ± 0.066	0.268HisCys: 0.268 ± 0.029	1.176HisAsp: 1.176 ± 0.059	1.232HisGlu: 1.232 ± 0.059	0.797HisPhe: 0.797 ± 0.043	1.763HisGly: 1.763 ± 0.067	0.536HisHis: 0.536 ± 0.04	1.162HisIle: 1.162 ± 0.049	0.667HisLys: 0.667 ± 0.037	1.964HisLeu: 1.964 ± 0.073	0.579HisMet: 0.579 ± 0.039	0.559HisAsn: 0.559 ± 0.038	1.133HisPro: 1.133 ± 0.05	0.592HisGln: 0.592 ± 0.033	1.313HisArg: 1.313 ± 0.055	1.068HisSer: 1.068 ± 0.053	1.099HisThr: 1.099 ± 0.055	1.772HisVal: 1.772 ± 0.066	0.286HisTrp: 0.286 ± 0.029	0.518HisTyr: 0.518 ± 0.037	0.0HisXaa: 0.0 ± 0.0
Ile	5.923IleAla: 5.923 ± 0.115	0.554IleCys: 0.554 ± 0.039	3.68IleAsp: 3.68 ± 0.106	3.432IleGlu: 3.432 ± 0.085	1.66IlePhe: 1.66 ± 0.069	4.7IleGly: 4.7 ± 0.117	0.901IleHis: 0.901 ± 0.045	3.158IleIle: 3.158 ± 0.112	1.962IleLys: 1.962 ± 0.072	5.466IleLeu: 5.466 ± 0.141	1.39IleMet: 1.39 ± 0.061	1.597IleAsn: 1.597 ± 0.064	2.831IlePro: 2.831 ± 0.094	1.592IleGln: 1.592 ± 0.072	3.376IleArg: 3.376 ± 0.09	3.453IleSer: 3.453 ± 0.105	3.266IleThr: 3.266 ± 0.106	5.583IleVal: 5.583 ± 0.123	0.529IleTrp: 0.529 ± 0.039	1.311IleTyr: 1.311 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	3.962LysAla: 3.962 ± 0.114	0.304LysCys: 0.304 ± 0.029	2.27LysAsp: 2.27 ± 0.081	2.626LysGlu: 2.626 ± 0.109	1.079LysPhe: 1.079 ± 0.054	3.308LysGly: 3.308 ± 0.088	0.7LysHis: 0.7 ± 0.042	1.917LysIle: 1.917 ± 0.082	2.088LysLys: 2.088 ± 0.083	3.649LysLeu: 3.649 ± 0.106	1.117LysMet: 1.117 ± 0.055	1.272LysAsn: 1.272 ± 0.062	1.896LysPro: 1.896 ± 0.063	1.475LysGln: 1.475 ± 0.062	2.358LysArg: 2.358 ± 0.07	2.387LysSer: 2.387 ± 0.072	2.685LysThr: 2.685 ± 0.086	3.281LysVal: 3.281 ± 0.084	0.383LysTrp: 0.383 ± 0.032	1.218LysTyr: 1.218 ± 0.057	0.0LysXaa: 0.0 ± 0.0
Leu	10.651LeuAla: 10.651 ± 0.175	1.009LeuCys: 1.009 ± 0.057	5.752LeuAsp: 5.752 ± 0.126	5.594LeuGlu: 5.594 ± 0.146	3.775LeuPhe: 3.775 ± 0.106	8.054LeuGly: 8.054 ± 0.143	2.047LeuHis: 2.047 ± 0.067	4.822LeuIle: 4.822 ± 0.115	4.034LeuLys: 4.034 ± 0.108	10.284LeuLeu: 10.284 ± 0.193	2.462LeuMet: 2.462 ± 0.083	2.809LeuAsn: 2.809 ± 0.081	4.887LeuPro: 4.887 ± 0.106	3.401LeuGln: 3.401 ± 0.096	6.27LeuArg: 6.27 ± 0.142	6.869LeuSer: 6.869 ± 0.135	6.198LeuThr: 6.198 ± 0.138	8.709LeuVal: 8.709 ± 0.177	1.061LeuTrp: 1.061 ± 0.054	2.55LeuTyr: 2.55 ± 0.086	0.0LeuXaa: 0.0 ± 0.0
Met	2.595MetAla: 2.595 ± 0.086	0.198MetCys: 0.198 ± 0.022	1.504MetAsp: 1.504 ± 0.058	1.5MetGlu: 1.5 ± 0.063	0.923MetPhe: 0.923 ± 0.055	2.0MetGly: 2.0 ± 0.077	0.511MetHis: 0.511 ± 0.034	1.387MetIle: 1.387 ± 0.057	1.318MetLys: 1.318 ± 0.058	2.563MetLeu: 2.563 ± 0.08	0.633MetMet: 0.633 ± 0.045	1.072MetAsn: 1.072 ± 0.05	1.187MetPro: 1.187 ± 0.051	0.894MetGln: 0.894 ± 0.044	1.613MetArg: 1.613 ± 0.067	1.797MetSer: 1.797 ± 0.064	1.917MetThr: 1.917 ± 0.068	2.095MetVal: 2.095 ± 0.064	0.182MetTrp: 0.182 ± 0.02	0.577MetTyr: 0.577 ± 0.036	0.0MetXaa: 0.0 ± 0.0
Asn	2.669AsnAla: 2.669 ± 0.084	0.322AsnCys: 0.322 ± 0.027	1.405AsnAsp: 1.405 ± 0.061	1.459AsnGlu: 1.459 ± 0.065	0.887AsnPhe: 0.887 ± 0.041	2.477AsnGly: 2.477 ± 0.087	0.5AsnHis: 0.5 ± 0.034	1.664AsnIle: 1.664 ± 0.063	1.065AsnLys: 1.065 ± 0.056	2.973AsnLeu: 2.973 ± 0.073	0.878AsnMet: 0.878 ± 0.048	0.759AsnAsn: 0.759 ± 0.047	1.874AsnPro: 1.874 ± 0.078	0.8AsnGln: 0.8 ± 0.04	1.547AsnArg: 1.547 ± 0.061	1.489AsnSer: 1.489 ± 0.066	1.554AsnThr: 1.554 ± 0.071	2.538AsnVal: 2.538 ± 0.082	0.426AsnTrp: 0.426 ± 0.035	0.831AsnTyr: 0.831 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	4.455ProAla: 4.455 ± 0.125	0.417ProCys: 0.417 ± 0.029	2.689ProAsp: 2.689 ± 0.079	3.234ProGlu: 3.234 ± 0.091	1.851ProPhe: 1.851 ± 0.071	3.797ProGly: 3.797 ± 0.09	0.917ProHis: 0.917 ± 0.048	2.34ProIle: 2.34 ± 0.077	1.306ProLys: 1.306 ± 0.054	3.998ProLeu: 3.998 ± 0.102	1.187ProMet: 1.187 ± 0.057	1.146ProAsn: 1.146 ± 0.049	1.579ProPro: 1.579 ± 0.065	1.408ProGln: 1.408 ± 0.065	2.363ProArg: 2.363 ± 0.073	2.984ProSer: 2.984 ± 0.099	2.61ProThr: 2.61 ± 0.076	4.324ProVal: 4.324 ± 0.113	0.563ProTrp: 0.563 ± 0.037	1.367ProTyr: 1.367 ± 0.062	0.0ProXaa: 0.0 ± 0.0
Gln	3.263GlnAla: 3.263 ± 0.082	0.288GlnCys: 0.288 ± 0.026	1.579GlnAsp: 1.579 ± 0.06	2.092GlnGlu: 2.092 ± 0.074	1.227GlnPhe: 1.227 ± 0.054	2.635GlnGly: 2.635 ± 0.082	0.712GlnHis: 0.712 ± 0.039	1.615GlnIle: 1.615 ± 0.066	1.522GlnLys: 1.522 ± 0.058	3.435GlnLeu: 3.435 ± 0.111	0.86GlnMet: 0.86 ± 0.045	0.921GlnAsn: 0.921 ± 0.05	1.489GlnPro: 1.489 ± 0.064	1.374GlnGln: 1.374 ± 0.067	2.013GlnArg: 2.013 ± 0.07	1.881GlnSer: 1.881 ± 0.064	1.995GlnThr: 1.995 ± 0.073	2.617GlnVal: 2.617 ± 0.081	0.356GlnTrp: 0.356 ± 0.033	1.027GlnTyr: 1.027 ± 0.052	0.0GlnXaa: 0.0 ± 0.0
Arg	5.022ArgAla: 5.022 ± 0.121	0.637ArgCys: 0.637 ± 0.036	3.358ArgAsp: 3.358 ± 0.1	4.018ArgGlu: 4.018 ± 0.097	2.457ArgPhe: 2.457 ± 0.075	4.065ArgGly: 4.065 ± 0.096	1.329ArgHis: 1.329 ± 0.053	3.827ArgIle: 3.827 ± 0.089	2.763ArgLys: 2.763 ± 0.08	6.331ArgLeu: 6.331 ± 0.132	1.667ArgMet: 1.667 ± 0.059	1.804ArgAsn: 1.804 ± 0.064	2.302ArgPro: 2.302 ± 0.087	2.185ArgGln: 2.185 ± 0.081	4.198ArgArg: 4.198 ± 0.122	3.763ArgSer: 3.763 ± 0.1	3.84ArgThr: 3.84 ± 0.097	4.741ArgVal: 4.741 ± 0.104	0.642ArgTrp: 0.642 ± 0.04	1.754ArgTyr: 1.754 ± 0.06	0.0ArgXaa: 0.0 ± 0.0
Ser	5.522SerAla: 5.522 ± 0.127	0.68SerCys: 0.68 ± 0.043	3.234SerAsp: 3.234 ± 0.086	3.04SerGlu: 3.04 ± 0.098	2.691SerPhe: 2.691 ± 0.085	5.784SerGly: 5.784 ± 0.151	1.167SerHis: 1.167 ± 0.05	3.856SerIle: 3.856 ± 0.11	2.239SerLys: 2.239 ± 0.083	6.444SerLeu: 6.444 ± 0.146	1.829SerMet: 1.829 ± 0.07	1.579SerAsn: 1.579 ± 0.076	2.779SerPro: 2.779 ± 0.087	1.962SerGln: 1.962 ± 0.068	3.736SerArg: 3.736 ± 0.099	4.52SerSer: 4.52 ± 0.135	3.777SerThr: 3.777 ± 0.127	5.489SerVal: 5.489 ± 0.118	0.77SerTrp: 0.77 ± 0.051	1.766SerTyr: 1.766 ± 0.067	0.002SerXaa: 0.002 ± 0.002
Thr	6.054ThrAla: 6.054 ± 0.155	0.581ThrCys: 0.581 ± 0.039	3.198ThrAsp: 3.198 ± 0.098	3.02ThrGlu: 3.02 ± 0.082	2.304ThrPhe: 2.304 ± 0.091	5.462ThrGly: 5.462 ± 0.129	1.14ThrHis: 1.14 ± 0.056	3.817ThrIle: 3.817 ± 0.121	2.135ThrLys: 2.135 ± 0.073	6.016ThrLeu: 6.016 ± 0.122	1.727ThrMet: 1.727 ± 0.069	1.538ThrAsn: 1.538 ± 0.067	3.311ThrPro: 3.311 ± 0.095	1.806ThrGln: 1.806 ± 0.064	3.396ThrArg: 3.396 ± 0.085	3.955ThrSer: 3.955 ± 0.124	4.056ThrThr: 4.056 ± 0.131	5.912ThrVal: 5.912 ± 0.147	0.804ThrTrp: 0.804 ± 0.061	1.754ThrTyr: 1.754 ± 0.082	0.0ThrXaa: 0.0 ± 0.0
Val	8.754ValAla: 8.754 ± 0.146	1.018ValCys: 1.018 ± 0.046	4.935ValAsp: 4.935 ± 0.108	4.894ValGlu: 4.894 ± 0.12	3.466ValPhe: 3.466 ± 0.098	6.344ValGly: 6.344 ± 0.123	1.73ValHis: 1.73 ± 0.066	4.554ValIle: 4.554 ± 0.11	3.07ValLys: 3.07 ± 0.088	9.254ValLeu: 9.254 ± 0.157	2.088ValMet: 2.088 ± 0.077	2.365ValAsn: 2.365 ± 0.079	4.054ValPro: 4.054 ± 0.098	2.896ValGln: 2.896 ± 0.097	5.191ValArg: 5.191 ± 0.109	5.594ValSer: 5.594 ± 0.114	5.779ValThr: 5.779 ± 0.153	8.036ValVal: 8.036 ± 0.163	0.885ValTrp: 0.885 ± 0.042	2.106ValTyr: 2.106 ± 0.063	0.0ValXaa: 0.0 ± 0.0
Trp	0.876TrpAla: 0.876 ± 0.043	0.119TrpCys: 0.119 ± 0.017	0.536TrpAsp: 0.536 ± 0.035	0.559TrpGlu: 0.559 ± 0.04	0.52TrpPhe: 0.52 ± 0.038	0.759TrpGly: 0.759 ± 0.048	0.248TrpHis: 0.248 ± 0.024	0.624TrpIle: 0.624 ± 0.037	0.509TrpLys: 0.509 ± 0.033	1.212TrpLeu: 1.212 ± 0.071	0.259TrpMet: 0.259 ± 0.023	0.541TrpAsn: 0.541 ± 0.042	0.421TrpPro: 0.421 ± 0.036	0.502TrpGln: 0.502 ± 0.037	0.671TrpArg: 0.671 ± 0.038	0.838TrpSer: 0.838 ± 0.049	0.721TrpThr: 0.721 ± 0.06	0.741TrpVal: 0.741 ± 0.045	0.203TrpTrp: 0.203 ± 0.022	0.412TrpTyr: 0.412 ± 0.031	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.716TyrAla: 2.716 ± 0.082	0.32TyrCys: 0.32 ± 0.027	1.631TyrAsp: 1.631 ± 0.066	1.466TyrGlu: 1.466 ± 0.065	1.032TyrPhe: 1.032 ± 0.048	2.372TyrGly: 2.372 ± 0.074	0.714TyrHis: 0.714 ± 0.044	1.486TyrIle: 1.486 ± 0.066	0.885TyrLys: 0.885 ± 0.046	2.892TyrLeu: 2.892 ± 0.09	0.595TyrMet: 0.595 ± 0.034	0.7TyrAsn: 0.7 ± 0.041	1.302TyrPro: 1.302 ± 0.052	0.881TyrGln: 0.881 ± 0.042	1.815TyrArg: 1.815 ± 0.062	1.59TyrSer: 1.59 ± 0.07	1.572TyrThr: 1.572 ± 0.074	2.392TyrVal: 2.392 ± 0.084	0.336TyrTrp: 0.336 ± 0.031	0.89TyrTyr: 0.89 ± 0.052	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.002	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 1392 proteins (444009 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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