Amino acid dipepetide frequency for Mumps virus (strain Miyahara vaccine) (MuV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.024AlaAla: 5.024 ± 1.826
1.005AlaCys: 1.005 ± 0.574
3.014AlaAsp: 3.014 ± 1.103
2.211AlaGlu: 2.211 ± 0.863
1.809AlaPhe: 1.809 ± 0.655
4.823AlaGly: 4.823 ± 1.137
1.005AlaHis: 1.005 ± 0.462
4.421AlaIle: 4.421 ± 1.191
3.014AlaLys: 3.014 ± 1.616
6.029AlaLeu: 6.029 ± 0.93
0.804AlaMet: 0.804 ± 0.512
3.617AlaAsn: 3.617 ± 0.707
3.014AlaPro: 3.014 ± 0.869
3.416AlaGln: 3.416 ± 1.08
5.225AlaArg: 5.225 ± 2.048
7.235AlaSer: 7.235 ± 1.699
4.823AlaThr: 4.823 ± 1.898
3.014AlaVal: 3.014 ± 1.723
0.402AlaTrp: 0.402 ± 0.328
2.412AlaTyr: 2.412 ± 0.739
0.0AlaXaa: 0.0 ± 0.0
Cys
1.005CysAla: 1.005 ± 0.463
0.603CysCys: 0.603 ± 0.264
0.402CysAsp: 0.402 ± 0.329
1.206CysGlu: 1.206 ± 0.476
1.005CysPhe: 1.005 ± 0.463
0.402CysGly: 0.402 ± 0.246
0.201CysHis: 0.201 ± 0.298
1.407CysIle: 1.407 ± 0.671
1.407CysLys: 1.407 ± 0.944
1.809CysLeu: 1.809 ± 0.653
0.402CysMet: 0.402 ± 0.381
0.603CysAsn: 0.603 ± 0.357
0.603CysPro: 0.603 ± 0.302
1.407CysGln: 1.407 ± 0.7
0.402CysArg: 0.402 ± 0.424
2.613CysSer: 2.613 ± 0.861
0.603CysThr: 0.603 ± 0.441
1.809CysVal: 1.809 ± 0.549
0.201CysTrp: 0.201 ± 0.261
1.206CysTyr: 1.206 ± 0.457
0.0CysXaa: 0.0 ± 0.0
Asp
2.01AspAla: 2.01 ± 0.403
0.804AspCys: 0.804 ± 0.354
3.014AspAsp: 3.014 ± 0.839
2.613AspGlu: 2.613 ± 0.798
1.608AspPhe: 1.608 ± 0.406
2.613AspGly: 2.613 ± 0.55
1.407AspHis: 1.407 ± 0.805
4.019AspIle: 4.019 ± 1.039
2.211AspLys: 2.211 ± 0.735
5.627AspLeu: 5.627 ± 1.171
0.402AspMet: 0.402 ± 0.255
2.814AspAsn: 2.814 ± 0.762
4.019AspPro: 4.019 ± 0.897
2.412AspGln: 2.412 ± 0.668
1.809AspArg: 1.809 ± 1.042
2.211AspSer: 2.211 ± 0.722
1.608AspThr: 1.608 ± 0.705
1.608AspVal: 1.608 ± 0.614
0.402AspTrp: 0.402 ± 0.234
2.412AspTyr: 2.412 ± 0.75
0.0AspXaa: 0.0 ± 0.0
Glu
1.809GluAla: 1.809 ± 0.833
0.603GluCys: 0.603 ± 0.389
2.211GluAsp: 2.211 ± 0.491
2.613GluGlu: 2.613 ± 0.989
1.809GluPhe: 1.809 ± 0.478
3.818GluGly: 3.818 ± 0.743
1.206GluHis: 1.206 ± 0.594
4.421GluIle: 4.421 ± 0.682
2.211GluLys: 2.211 ± 1.026
5.828GluLeu: 5.828 ± 0.989
1.407GluMet: 1.407 ± 0.518
2.412GluAsn: 2.412 ± 0.358
2.01GluPro: 2.01 ± 0.486
3.014GluGln: 3.014 ± 0.896
3.014GluArg: 3.014 ± 0.565
3.215GluSer: 3.215 ± 0.778
2.814GluThr: 2.814 ± 0.553
1.809GluVal: 1.809 ± 0.416
0.804GluTrp: 0.804 ± 0.492
1.407GluTyr: 1.407 ± 0.907
0.0GluXaa: 0.0 ± 0.0
Phe
2.412PheAla: 2.412 ± 0.574
0.804PheCys: 0.804 ± 0.45
0.804PheAsp: 0.804 ± 0.518
2.412PheGlu: 2.412 ± 0.504
1.407PhePhe: 1.407 ± 0.364
0.804PheGly: 0.804 ± 0.344
0.603PheHis: 0.603 ± 0.357
2.814PheIle: 2.814 ± 0.598
1.206PheLys: 1.206 ± 0.637
3.818PheLeu: 3.818 ± 0.626
0.603PheMet: 0.603 ± 0.297
2.01PheAsn: 2.01 ± 1.041
1.206PhePro: 1.206 ± 0.473
1.206PheGln: 1.206 ± 0.555
1.809PheArg: 1.809 ± 1.03
3.416PheSer: 3.416 ± 0.73
2.613PheThr: 2.613 ± 1.087
2.01PheVal: 2.01 ± 0.399
0.0PheTrp: 0.0 ± 0.0
1.608PheTyr: 1.608 ± 0.498
0.0PheXaa: 0.0 ± 0.0
Gly
3.617GlyAla: 3.617 ± 1.18
1.608GlyCys: 1.608 ± 0.634
3.818GlyAsp: 3.818 ± 0.824
3.215GlyGlu: 3.215 ± 0.854
1.407GlyPhe: 1.407 ± 0.418
4.019GlyGly: 4.019 ± 1.471
1.005GlyHis: 1.005 ± 0.358
4.421GlyIle: 4.421 ± 0.809
2.211GlyLys: 2.211 ± 0.379
4.22GlyLeu: 4.22 ± 0.843
1.608GlyMet: 1.608 ± 0.786
2.814GlyAsn: 2.814 ± 1.279
2.01GlyPro: 2.01 ± 0.809
2.412GlyGln: 2.412 ± 0.438
2.814GlyArg: 2.814 ± 0.523
5.627GlySer: 5.627 ± 1.593
3.416GlyThr: 3.416 ± 1.299
4.421GlyVal: 4.421 ± 1.04
0.402GlyTrp: 0.402 ± 0.255
1.407GlyTyr: 1.407 ± 0.361
0.0GlyXaa: 0.0 ± 0.0
His
1.809HisAla: 1.809 ± 0.468
0.201HisCys: 0.201 ± 0.13
0.603HisAsp: 0.603 ± 0.262
0.402HisGlu: 0.402 ± 0.259
0.402HisPhe: 0.402 ± 0.368
1.407HisGly: 1.407 ± 0.549
1.005HisHis: 1.005 ± 0.512
1.809HisIle: 1.809 ± 0.622
0.804HisLys: 0.804 ± 0.348
2.814HisLeu: 2.814 ± 0.944
0.603HisMet: 0.603 ± 0.324
0.402HisAsn: 0.402 ± 0.217
1.005HisPro: 1.005 ± 0.316
2.01HisGln: 2.01 ± 1.163
0.804HisArg: 0.804 ± 0.321
1.005HisSer: 1.005 ± 0.413
0.402HisThr: 0.402 ± 0.217
0.804HisVal: 0.804 ± 0.354
0.201HisTrp: 0.201 ± 0.242
0.201HisTyr: 0.201 ± 0.13
0.0HisXaa: 0.0 ± 0.0
Ile
5.627IleAla: 5.627 ± 1.227
0.804IleCys: 0.804 ± 0.338
3.014IleAsp: 3.014 ± 0.831
4.823IleGlu: 4.823 ± 1.445
1.608IlePhe: 1.608 ± 0.406
4.019IleGly: 4.019 ± 0.808
1.407IleHis: 1.407 ± 0.48
5.828IleIle: 5.828 ± 1.145
3.215IleLys: 3.215 ± 0.936
8.842IleLeu: 8.842 ± 2.273
2.01IleMet: 2.01 ± 0.64
6.029IleAsn: 6.029 ± 2.015
4.823IlePro: 4.823 ± 1.003
4.823IleGln: 4.823 ± 1.567
3.818IleArg: 3.818 ± 0.613
6.431IleSer: 6.431 ± 1.668
3.818IleThr: 3.818 ± 0.715
4.22IleVal: 4.22 ± 1.729
1.608IleTrp: 1.608 ± 1.036
1.608IleTyr: 1.608 ± 0.59
0.0IleXaa: 0.0 ± 0.0
Lys
2.814LysAla: 2.814 ± 0.661
1.206LysCys: 1.206 ± 0.539
1.608LysAsp: 1.608 ± 0.463
2.613LysGlu: 2.613 ± 0.791
1.005LysPhe: 1.005 ± 0.316
2.412LysGly: 2.412 ± 0.79
0.603LysHis: 0.603 ± 0.389
3.014LysIle: 3.014 ± 0.896
1.608LysLys: 1.608 ± 0.521
4.421LysLeu: 4.421 ± 0.839
0.804LysMet: 0.804 ± 0.285
1.608LysAsn: 1.608 ± 0.677
1.809LysPro: 1.809 ± 0.805
2.412LysGln: 2.412 ± 0.686
1.809LysArg: 1.809 ± 0.576
3.416LysSer: 3.416 ± 0.666
3.617LysThr: 3.617 ± 0.813
3.215LysVal: 3.215 ± 0.591
0.603LysTrp: 0.603 ± 0.297
2.01LysTyr: 2.01 ± 0.626
0.0LysXaa: 0.0 ± 0.0
Leu
7.838LeuAla: 7.838 ± 0.972
2.211LeuCys: 2.211 ± 0.72
5.828LeuAsp: 5.828 ± 1.177
5.627LeuGlu: 5.627 ± 1.568
3.617LeuPhe: 3.617 ± 0.417
3.416LeuGly: 3.416 ± 0.716
1.407LeuHis: 1.407 ± 0.737
7.838LeuIle: 7.838 ± 1.135
4.823LeuLys: 4.823 ± 1.658
10.651LeuLeu: 10.651 ± 1.76
2.814LeuMet: 2.814 ± 0.823
6.23LeuAsn: 6.23 ± 1.986
4.823LeuPro: 4.823 ± 0.798
3.215LeuGln: 3.215 ± 0.672
5.828LeuArg: 5.828 ± 1.129
11.254LeuSer: 11.254 ± 2.186
9.043LeuThr: 9.043 ± 2.165
5.426LeuVal: 5.426 ± 1.626
1.005LeuTrp: 1.005 ± 0.442
2.814LeuTyr: 2.814 ± 0.789
0.0LeuXaa: 0.0 ± 0.0
Met
1.608MetAla: 1.608 ± 0.73
0.402MetCys: 0.402 ± 0.259
1.407MetAsp: 1.407 ± 1.004
1.809MetGlu: 1.809 ± 0.32
0.201MetPhe: 0.201 ± 0.242
1.206MetGly: 1.206 ± 0.457
0.0MetHis: 0.0 ± 0.0
2.211MetIle: 2.211 ± 0.735
1.206MetLys: 1.206 ± 0.499
2.01MetLeu: 2.01 ± 0.943
0.402MetMet: 0.402 ± 0.337
1.608MetAsn: 1.608 ± 0.37
1.005MetPro: 1.005 ± 0.376
0.603MetGln: 0.603 ± 0.246
1.809MetArg: 1.809 ± 0.755
1.608MetSer: 1.608 ± 0.362
1.407MetThr: 1.407 ± 0.516
1.407MetVal: 1.407 ± 0.537
0.402MetTrp: 0.402 ± 0.255
0.804MetTyr: 0.804 ± 0.353
0.0MetXaa: 0.0 ± 0.0
Asn
3.416AsnAla: 3.416 ± 0.726
1.407AsnCys: 1.407 ± 1.1
2.211AsnAsp: 2.211 ± 0.676
2.412AsnGlu: 2.412 ± 0.599
1.407AsnPhe: 1.407 ± 0.302
2.613AsnGly: 2.613 ± 0.898
2.412AsnHis: 2.412 ± 0.602
4.22AsnIle: 4.22 ± 1.634
1.608AsnLys: 1.608 ± 0.39
4.421AsnLeu: 4.421 ± 1.191
1.005AsnMet: 1.005 ± 0.405
2.814AsnAsn: 2.814 ± 0.582
4.019AsnPro: 4.019 ± 0.897
3.416AsnGln: 3.416 ± 1.586
3.617AsnArg: 3.617 ± 0.667
4.22AsnSer: 4.22 ± 0.541
2.01AsnThr: 2.01 ± 0.891
2.211AsnVal: 2.211 ± 0.529
1.206AsnTrp: 1.206 ± 0.58
1.407AsnTyr: 1.407 ± 0.772
0.0AsnXaa: 0.0 ± 0.0
Pro
3.014ProAla: 3.014 ± 1.221
0.402ProCys: 0.402 ± 0.328
2.814ProAsp: 2.814 ± 0.656
3.014ProGlu: 3.014 ± 0.899
2.211ProPhe: 2.211 ± 0.777
3.215ProGly: 3.215 ± 1.062
0.402ProHis: 0.402 ± 0.259
4.823ProIle: 4.823 ± 1.276
1.809ProLys: 1.809 ± 0.594
5.627ProLeu: 5.627 ± 1.119
0.804ProMet: 0.804 ± 0.292
2.814ProAsn: 2.814 ± 0.964
3.215ProPro: 3.215 ± 0.836
2.814ProGln: 2.814 ± 0.804
1.608ProArg: 1.608 ± 0.645
3.818ProSer: 3.818 ± 0.848
5.627ProThr: 5.627 ± 1.435
3.617ProVal: 3.617 ± 1.594
0.201ProTrp: 0.201 ± 0.242
1.809ProTyr: 1.809 ± 0.851
0.0ProXaa: 0.0 ± 0.0
Gln
4.22GlnAla: 4.22 ± 0.933
0.201GlnCys: 0.201 ± 0.251
3.416GlnAsp: 3.416 ± 0.938
1.005GlnGlu: 1.005 ± 0.434
1.608GlnPhe: 1.608 ± 0.516
4.622GlnGly: 4.622 ± 1.393
0.402GlnHis: 0.402 ± 0.393
4.622GlnIle: 4.622 ± 1.337
1.608GlnLys: 1.608 ± 0.482
4.823GlnLeu: 4.823 ± 1.05
1.608GlnMet: 1.608 ± 0.505
1.809GlnAsn: 1.809 ± 1.312
3.416GlnPro: 3.416 ± 1.48
2.814GlnGln: 2.814 ± 1.673
2.211GlnArg: 2.211 ± 0.593
3.617GlnSer: 3.617 ± 0.483
3.014GlnThr: 3.014 ± 0.653
3.416GlnVal: 3.416 ± 0.434
0.201GlnTrp: 0.201 ± 0.261
2.211GlnTyr: 2.211 ± 0.42
0.0GlnXaa: 0.0 ± 0.0
Arg
2.412ArgAla: 2.412 ± 0.495
0.603ArgCys: 0.603 ± 0.449
1.608ArgAsp: 1.608 ± 0.516
1.608ArgGlu: 1.608 ± 0.581
2.01ArgPhe: 2.01 ± 0.698
2.613ArgGly: 2.613 ± 1.278
1.005ArgHis: 1.005 ± 0.714
4.421ArgIle: 4.421 ± 1.236
2.613ArgLys: 2.613 ± 0.908
6.632ArgLeu: 6.632 ± 1.128
1.206ArgMet: 1.206 ± 0.345
1.206ArgAsn: 1.206 ± 0.318
3.014ArgPro: 3.014 ± 0.679
2.01ArgGln: 2.01 ± 0.807
4.22ArgArg: 4.22 ± 0.885
5.426ArgSer: 5.426 ± 0.627
1.608ArgThr: 1.608 ± 0.442
4.22ArgVal: 4.22 ± 0.972
0.402ArgTrp: 0.402 ± 0.303
2.01ArgTyr: 2.01 ± 1.043
0.0ArgXaa: 0.0 ± 0.0
Ser
5.627SerAla: 5.627 ± 1.629
2.211SerCys: 2.211 ± 0.662
4.019SerAsp: 4.019 ± 1.371
3.416SerGlu: 3.416 ± 1.295
3.215SerPhe: 3.215 ± 0.797
5.426SerGly: 5.426 ± 1.821
1.809SerHis: 1.809 ± 0.429
4.421SerIle: 4.421 ± 1.549
4.22SerLys: 4.22 ± 1.197
10.45SerLeu: 10.45 ± 1.773
2.814SerMet: 2.814 ± 0.664
4.421SerAsn: 4.421 ± 1.011
4.22SerPro: 4.22 ± 0.838
4.019SerGln: 4.019 ± 1.094
2.01SerArg: 2.01 ± 0.648
8.24SerSer: 8.24 ± 1.783
5.627SerThr: 5.627 ± 1.26
4.421SerVal: 4.421 ± 0.851
1.608SerTrp: 1.608 ± 0.473
4.019SerTyr: 4.019 ± 0.874
0.0SerXaa: 0.0 ± 0.0
Thr
5.225ThrAla: 5.225 ± 0.887
1.407ThrCys: 1.407 ± 0.588
2.211ThrAsp: 2.211 ± 0.448
2.613ThrGlu: 2.613 ± 0.474
2.613ThrPhe: 2.613 ± 0.786
4.622ThrGly: 4.622 ± 1.777
0.804ThrHis: 0.804 ± 0.677
6.632ThrIle: 6.632 ± 1.571
2.211ThrLys: 2.211 ± 0.677
7.637ThrLeu: 7.637 ± 1.378
1.005ThrMet: 1.005 ± 0.624
2.412ThrAsn: 2.412 ± 0.802
3.416ThrPro: 3.416 ± 0.691
3.416ThrGln: 3.416 ± 1.041
3.416ThrArg: 3.416 ± 1.093
4.019ThrSer: 4.019 ± 0.676
4.421ThrThr: 4.421 ± 0.713
4.019ThrVal: 4.019 ± 0.543
0.603ThrTrp: 0.603 ± 0.389
1.407ThrTyr: 1.407 ± 0.563
0.0ThrXaa: 0.0 ± 0.0
Val
3.215ValAla: 3.215 ± 1.456
1.206ValCys: 1.206 ± 0.852
2.211ValAsp: 2.211 ± 0.461
3.014ValGlu: 3.014 ± 0.937
2.613ValPhe: 2.613 ± 1.104
2.211ValGly: 2.211 ± 1.002
1.809ValHis: 1.809 ± 0.754
3.215ValIle: 3.215 ± 0.794
2.814ValLys: 2.814 ± 1.062
5.627ValLeu: 5.627 ± 0.556
1.608ValMet: 1.608 ± 0.467
3.416ValAsn: 3.416 ± 0.944
3.014ValPro: 3.014 ± 0.78
3.014ValGln: 3.014 ± 0.773
2.613ValArg: 2.613 ± 0.509
4.421ValSer: 4.421 ± 1.067
5.426ValThr: 5.426 ± 2.242
3.014ValVal: 3.014 ± 0.781
0.603ValTrp: 0.603 ± 0.422
2.613ValTyr: 2.613 ± 0.825
0.0ValXaa: 0.0 ± 0.0
Trp
1.206TrpAla: 1.206 ± 0.371
0.603TrpCys: 0.603 ± 0.302
0.201TrpAsp: 0.201 ± 0.233
0.402TrpGlu: 0.402 ± 0.259
0.603TrpPhe: 0.603 ± 0.274
0.603TrpGly: 0.603 ± 0.274
0.0TrpHis: 0.0 ± 0.0
0.804TrpIle: 0.804 ± 0.358
0.603TrpLys: 0.603 ± 0.389
0.402TrpLeu: 0.402 ± 0.259
0.201TrpMet: 0.201 ± 0.13
0.603TrpAsn: 0.603 ± 0.262
0.804TrpPro: 0.804 ± 0.433
0.402TrpGln: 0.402 ± 0.259
0.402TrpArg: 0.402 ± 0.259
1.608TrpSer: 1.608 ± 0.729
0.402TrpThr: 0.402 ± 0.259
0.804TrpVal: 0.804 ± 0.397
0.201TrpTrp: 0.201 ± 0.242
0.402TrpTyr: 0.402 ± 0.259
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.412TyrAla: 2.412 ± 1.111
1.005TyrCys: 1.005 ± 0.46
1.206TyrAsp: 1.206 ± 0.431
1.407TyrGlu: 1.407 ± 0.503
1.407TyrPhe: 1.407 ± 0.969
1.608TyrGly: 1.608 ± 0.473
0.201TyrHis: 0.201 ± 0.233
3.014TyrIle: 3.014 ± 0.528
1.206TyrLys: 1.206 ± 0.477
4.22TyrLeu: 4.22 ± 1.411
0.804TyrMet: 0.804 ± 0.418
2.412TyrAsn: 2.412 ± 0.539
2.211TyrPro: 2.211 ± 0.586
2.01TyrGln: 2.01 ± 0.299
1.608TyrArg: 1.608 ± 0.513
2.814TyrSer: 2.814 ± 0.482
1.809TyrThr: 1.809 ± 0.664
2.211TyrVal: 2.211 ± 0.414
0.201TyrTrp: 0.201 ± 0.13
1.407TyrTyr: 1.407 ± 0.361
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (4977 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski