Amino acid dipepetide frequency for Crocuta crocuta papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.532AlaAla: 5.532 ± 1.471
1.702AlaCys: 1.702 ± 0.961
3.83AlaAsp: 3.83 ± 1.684
2.128AlaGlu: 2.128 ± 0.643
3.83AlaPhe: 3.83 ± 1.018
1.277AlaGly: 1.277 ± 1.105
0.426AlaHis: 0.426 ± 0.35
2.128AlaIle: 2.128 ± 0.421
4.255AlaLys: 4.255 ± 1.735
5.106AlaLeu: 5.106 ± 0.867
1.277AlaMet: 1.277 ± 0.665
1.702AlaAsn: 1.702 ± 0.599
2.979AlaPro: 2.979 ± 1.689
1.277AlaGln: 1.277 ± 0.641
3.404AlaArg: 3.404 ± 1.169
3.404AlaSer: 3.404 ± 0.747
4.681AlaThr: 4.681 ± 1.301
3.83AlaVal: 3.83 ± 1.987
1.277AlaTrp: 1.277 ± 1.01
1.702AlaTyr: 1.702 ± 0.58
0.0AlaXaa: 0.0 ± 0.0
Cys
0.851CysAla: 0.851 ± 0.48
2.128CysCys: 2.128 ± 1.465
0.851CysAsp: 0.851 ± 0.421
1.277CysGlu: 1.277 ± 0.837
2.128CysPhe: 2.128 ± 0.82
1.702CysGly: 1.702 ± 1.16
0.426CysHis: 0.426 ± 0.514
0.851CysIle: 0.851 ± 0.463
2.979CysLys: 2.979 ± 1.218
2.979CysLeu: 2.979 ± 1.94
1.277CysMet: 1.277 ± 0.721
0.0CysAsn: 0.0 ± 0.0
1.702CysPro: 1.702 ± 0.599
0.426CysGln: 0.426 ± 0.376
1.702CysArg: 1.702 ± 1.088
0.851CysSer: 0.851 ± 0.699
0.851CysThr: 0.851 ± 0.513
0.851CysVal: 0.851 ± 0.746
0.426CysTrp: 0.426 ± 0.35
0.426CysTyr: 0.426 ± 0.434
0.0CysXaa: 0.0 ± 0.0
Asp
1.702AspAla: 1.702 ± 0.615
1.277AspCys: 1.277 ± 0.641
3.404AspAsp: 3.404 ± 1.027
3.83AspGlu: 3.83 ± 0.499
4.255AspPhe: 4.255 ± 1.06
2.979AspGly: 2.979 ± 1.252
0.851AspHis: 0.851 ± 0.737
4.681AspIle: 4.681 ± 1.659
2.128AspLys: 2.128 ± 0.744
5.957AspLeu: 5.957 ± 1.922
1.277AspMet: 1.277 ± 0.478
2.553AspAsn: 2.553 ± 0.962
5.106AspPro: 5.106 ± 1.898
2.128AspGln: 2.128 ± 0.802
2.553AspArg: 2.553 ± 0.888
4.255AspSer: 4.255 ± 2.239
1.702AspThr: 1.702 ± 0.832
4.681AspVal: 4.681 ± 1.091
1.702AspTrp: 1.702 ± 1.398
1.702AspTyr: 1.702 ± 0.573
0.0AspXaa: 0.0 ± 0.0
Glu
3.83GluAla: 3.83 ± 0.943
0.851GluCys: 0.851 ± 0.615
4.681GluAsp: 4.681 ± 0.746
8.511GluGlu: 8.511 ± 3.757
2.553GluPhe: 2.553 ± 0.898
2.553GluGly: 2.553 ± 0.813
2.128GluHis: 2.128 ± 0.609
3.404GluIle: 3.404 ± 1.012
4.681GluLys: 4.681 ± 1.092
4.255GluLeu: 4.255 ± 1.125
0.426GluMet: 0.426 ± 0.398
3.83GluAsn: 3.83 ± 1.086
1.702GluPro: 1.702 ± 0.567
6.383GluGln: 6.383 ± 0.96
2.128GluArg: 2.128 ± 1.205
3.83GluSer: 3.83 ± 1.091
5.106GluThr: 5.106 ± 1.9
1.277GluVal: 1.277 ± 0.478
0.426GluTrp: 0.426 ± 0.434
1.277GluTyr: 1.277 ± 0.671
0.0GluXaa: 0.0 ± 0.0
Phe
2.553PheAla: 2.553 ± 0.962
2.128PheCys: 2.128 ± 0.568
2.979PheAsp: 2.979 ± 1.228
2.128PheGlu: 2.128 ± 1.106
2.128PhePhe: 2.128 ± 0.741
3.404PheGly: 3.404 ± 0.717
0.426PheHis: 0.426 ± 0.474
2.979PheIle: 2.979 ± 1.687
2.979PheLys: 2.979 ± 0.661
6.809PheLeu: 6.809 ± 1.441
0.426PheMet: 0.426 ± 0.434
2.979PheAsn: 2.979 ± 1.1
3.404PhePro: 3.404 ± 1.615
2.128PheGln: 2.128 ± 0.741
1.702PheArg: 1.702 ± 0.876
1.277PheSer: 1.277 ± 0.545
1.702PheThr: 1.702 ± 0.583
1.702PheVal: 1.702 ± 0.629
1.702PheTrp: 1.702 ± 0.58
2.128PheTyr: 2.128 ± 1.059
0.0PheXaa: 0.0 ± 0.0
Gly
1.702GlyAla: 1.702 ± 0.855
1.702GlyCys: 1.702 ± 1.121
3.404GlyAsp: 3.404 ± 1.214
4.681GlyGlu: 4.681 ± 1.436
1.277GlyPhe: 1.277 ± 0.393
5.532GlyGly: 5.532 ± 1.419
2.128GlyHis: 2.128 ± 1.277
3.83GlyIle: 3.83 ± 0.824
2.128GlyLys: 2.128 ± 1.264
3.83GlyLeu: 3.83 ± 1.593
0.426GlyMet: 0.426 ± 0.4
1.702GlyAsn: 1.702 ± 0.58
2.128GlyPro: 2.128 ± 0.721
2.553GlyGln: 2.553 ± 1.22
3.404GlyArg: 3.404 ± 2.216
5.532GlySer: 5.532 ± 1.847
5.532GlyThr: 5.532 ± 2.076
4.681GlyVal: 4.681 ± 1.251
0.426GlyTrp: 0.426 ± 0.35
1.702GlyTyr: 1.702 ± 1.013
0.0GlyXaa: 0.0 ± 0.0
His
1.277HisAla: 1.277 ± 0.478
0.0HisCys: 0.0 ± 0.0
0.851HisAsp: 0.851 ± 0.486
1.277HisGlu: 1.277 ± 0.641
0.426HisPhe: 0.426 ± 0.434
0.851HisGly: 0.851 ± 0.903
0.0HisHis: 0.0 ± 0.0
1.702HisIle: 1.702 ± 1.037
0.851HisLys: 0.851 ± 0.416
2.128HisLeu: 2.128 ± 1.12
0.0HisMet: 0.0 ± 0.0
0.851HisAsn: 0.851 ± 0.539
2.553HisPro: 2.553 ± 0.827
1.277HisGln: 1.277 ± 0.67
0.851HisArg: 0.851 ± 0.648
1.702HisSer: 1.702 ± 0.274
1.277HisThr: 1.277 ± 0.677
2.128HisVal: 2.128 ± 0.408
0.851HisTrp: 0.851 ± 0.486
1.277HisTyr: 1.277 ± 0.393
0.0HisXaa: 0.0 ± 0.0
Ile
3.83IleAla: 3.83 ± 1.174
0.426IleCys: 0.426 ± 0.514
3.83IleAsp: 3.83 ± 1.046
3.83IleGlu: 3.83 ± 1.195
2.553IlePhe: 2.553 ± 0.949
5.106IleGly: 5.106 ± 0.863
1.277IleHis: 1.277 ± 0.665
3.404IleIle: 3.404 ± 1.327
1.702IleLys: 1.702 ± 0.58
3.83IleLeu: 3.83 ± 0.59
0.0IleMet: 0.0 ± 0.0
1.702IleAsn: 1.702 ± 0.629
2.553IlePro: 2.553 ± 1.475
0.426IleGln: 0.426 ± 0.337
2.553IleArg: 2.553 ± 0.481
5.957IleSer: 5.957 ± 2.419
2.979IleThr: 2.979 ± 0.779
3.404IleVal: 3.404 ± 0.418
0.426IleTrp: 0.426 ± 0.35
3.83IleTyr: 3.83 ± 0.728
0.0IleXaa: 0.0 ± 0.0
Lys
3.404LysAla: 3.404 ± 1.027
2.553LysCys: 2.553 ± 0.739
2.979LysAsp: 2.979 ± 0.521
3.83LysGlu: 3.83 ± 1.232
4.681LysPhe: 4.681 ± 0.89
2.979LysGly: 2.979 ± 2.033
1.702LysHis: 1.702 ± 1.27
3.83LysIle: 3.83 ± 1.456
6.809LysLys: 6.809 ± 1.448
3.404LysLeu: 3.404 ± 1.123
1.277LysMet: 1.277 ± 0.782
2.553LysAsn: 2.553 ± 1.147
2.553LysPro: 2.553 ± 0.535
2.128LysGln: 2.128 ± 0.767
3.404LysArg: 3.404 ± 0.653
4.681LysSer: 4.681 ± 1.502
5.106LysThr: 5.106 ± 0.973
1.702LysVal: 1.702 ± 0.832
0.851LysTrp: 0.851 ± 0.539
1.702LysTyr: 1.702 ± 0.58
0.0LysXaa: 0.0 ± 0.0
Leu
6.809LeuAla: 6.809 ± 1.209
2.553LeuCys: 2.553 ± 1.488
4.681LeuAsp: 4.681 ± 1.096
5.957LeuGlu: 5.957 ± 1.82
5.957LeuPhe: 5.957 ± 1.214
5.957LeuGly: 5.957 ± 1.538
1.702LeuHis: 1.702 ± 0.719
3.404LeuIle: 3.404 ± 1.011
2.979LeuLys: 2.979 ± 1.124
12.34LeuLeu: 12.34 ± 3.796
0.426LeuMet: 0.426 ± 0.474
5.957LeuAsn: 5.957 ± 1.424
2.979LeuPro: 2.979 ± 1.377
6.383LeuGln: 6.383 ± 1.516
3.83LeuArg: 3.83 ± 1.114
6.809LeuSer: 6.809 ± 1.938
7.66LeuThr: 7.66 ± 1.89
3.404LeuVal: 3.404 ± 0.999
1.277LeuTrp: 1.277 ± 0.641
3.83LeuTyr: 3.83 ± 1.664
0.0LeuXaa: 0.0 ± 0.0
Met
2.128MetAla: 2.128 ± 1.065
0.0MetCys: 0.0 ± 0.0
0.851MetAsp: 0.851 ± 0.673
1.277MetGlu: 1.277 ± 0.654
0.426MetPhe: 0.426 ± 0.337
0.0MetGly: 0.0 ± 0.0
0.426MetHis: 0.426 ± 0.368
0.0MetIle: 0.0 ± 0.0
0.851MetLys: 0.851 ± 0.869
0.851MetLeu: 0.851 ± 0.463
0.0MetMet: 0.0 ± 0.0
1.277MetAsn: 1.277 ± 0.393
0.426MetPro: 0.426 ± 0.514
1.277MetGln: 1.277 ± 0.67
0.426MetArg: 0.426 ± 0.514
0.851MetSer: 0.851 ± 0.699
0.426MetThr: 0.426 ± 0.35
0.851MetVal: 0.851 ± 0.416
0.0MetTrp: 0.0 ± 0.0
0.426MetTyr: 0.426 ± 0.337
0.0MetXaa: 0.0 ± 0.0
Asn
2.979AsnAla: 2.979 ± 1.109
0.851AsnCys: 0.851 ± 0.421
2.979AsnAsp: 2.979 ± 1.078
2.979AsnGlu: 2.979 ± 1.456
2.128AsnPhe: 2.128 ± 0.867
1.702AsnGly: 1.702 ± 0.764
1.277AsnHis: 1.277 ± 0.688
2.128AsnIle: 2.128 ± 0.89
3.404AsnLys: 3.404 ± 1.328
5.106AsnLeu: 5.106 ± 1.742
0.426AsnMet: 0.426 ± 0.35
3.83AsnAsn: 3.83 ± 1.4
3.404AsnPro: 3.404 ± 1.313
1.702AsnGln: 1.702 ± 0.832
2.128AsnArg: 2.128 ± 0.648
2.128AsnSer: 2.128 ± 0.867
3.404AsnThr: 3.404 ± 1.063
2.979AsnVal: 2.979 ± 1.216
0.426AsnTrp: 0.426 ± 0.35
0.851AsnTyr: 0.851 ± 0.416
0.0AsnXaa: 0.0 ± 0.0
Pro
5.532ProAla: 5.532 ± 2.47
1.277ProCys: 1.277 ± 0.641
3.404ProAsp: 3.404 ± 0.999
2.128ProGlu: 2.128 ± 1.209
1.702ProPhe: 1.702 ± 0.917
1.702ProGly: 1.702 ± 0.574
0.426ProHis: 0.426 ± 0.474
3.83ProIle: 3.83 ± 1.695
5.106ProLys: 5.106 ± 1.687
6.809ProLeu: 6.809 ± 1.669
0.0ProMet: 0.0 ± 0.0
2.979ProAsn: 2.979 ± 1.202
6.383ProPro: 6.383 ± 1.736
0.851ProGln: 0.851 ± 0.419
2.553ProArg: 2.553 ± 0.474
5.957ProSer: 5.957 ± 1.426
2.128ProThr: 2.128 ± 0.97
3.83ProVal: 3.83 ± 2.014
0.426ProTrp: 0.426 ± 0.474
2.553ProTyr: 2.553 ± 1.203
0.0ProXaa: 0.0 ± 0.0
Gln
0.851GlnAla: 0.851 ± 0.463
0.851GlnCys: 0.851 ± 0.699
1.277GlnAsp: 1.277 ± 0.696
2.979GlnGlu: 2.979 ± 0.903
0.0GlnPhe: 0.0 ± 0.0
1.277GlnGly: 1.277 ± 1.01
1.277GlnHis: 1.277 ± 0.626
3.404GlnIle: 3.404 ± 1.002
1.277GlnLys: 1.277 ± 0.837
5.106GlnLeu: 5.106 ± 1.389
1.277GlnMet: 1.277 ± 0.825
4.255GlnAsn: 4.255 ± 0.967
2.979GlnPro: 2.979 ± 0.971
1.702GlnGln: 1.702 ± 0.777
2.128GlnArg: 2.128 ± 1.221
1.702GlnSer: 1.702 ± 0.819
2.979GlnThr: 2.979 ± 0.82
2.128GlnVal: 2.128 ± 0.959
0.851GlnTrp: 0.851 ± 0.48
0.851GlnTyr: 0.851 ± 0.539
0.0GlnXaa: 0.0 ± 0.0
Arg
2.553ArgAla: 2.553 ± 0.518
0.851ArgCys: 0.851 ± 0.807
2.128ArgAsp: 2.128 ± 0.423
2.128ArgGlu: 2.128 ± 0.802
3.83ArgPhe: 3.83 ± 1.239
5.106ArgGly: 5.106 ± 1.6
1.702ArgHis: 1.702 ± 0.858
1.277ArgIle: 1.277 ± 0.869
4.255ArgLys: 4.255 ± 1.527
5.532ArgLeu: 5.532 ± 1.523
0.0ArgMet: 0.0 ± 0.0
1.702ArgAsn: 1.702 ± 0.648
2.979ArgPro: 2.979 ± 1.039
0.851ArgGln: 0.851 ± 0.7
5.106ArgArg: 5.106 ± 1.712
3.83ArgSer: 3.83 ± 1.123
2.128ArgThr: 2.128 ± 0.408
4.255ArgVal: 4.255 ± 0.819
0.426ArgTrp: 0.426 ± 0.35
2.553ArgTyr: 2.553 ± 0.667
0.0ArgXaa: 0.0 ± 0.0
Ser
2.128SerAla: 2.128 ± 0.973
1.702SerCys: 1.702 ± 0.797
5.106SerAsp: 5.106 ± 2.439
4.681SerGlu: 4.681 ± 1.253
2.979SerPhe: 2.979 ± 0.903
5.957SerGly: 5.957 ± 1.775
0.851SerHis: 0.851 ± 0.7
3.83SerIle: 3.83 ± 1.297
4.681SerLys: 4.681 ± 1.061
6.383SerLeu: 6.383 ± 1.454
1.277SerMet: 1.277 ± 0.507
4.255SerAsn: 4.255 ± 1.619
3.404SerPro: 3.404 ± 0.695
3.83SerGln: 3.83 ± 1.563
4.681SerArg: 4.681 ± 1.487
5.532SerSer: 5.532 ± 1.116
7.234SerThr: 7.234 ± 1.8
5.106SerVal: 5.106 ± 1.21
0.426SerTrp: 0.426 ± 0.474
1.702SerTyr: 1.702 ± 0.675
0.0SerXaa: 0.0 ± 0.0
Thr
3.404ThrAla: 3.404 ± 1.148
1.277ThrCys: 1.277 ± 0.769
4.681ThrAsp: 4.681 ± 1.111
4.681ThrGlu: 4.681 ± 0.883
2.128ThrPhe: 2.128 ± 1.33
3.404ThrGly: 3.404 ± 0.731
0.851ThrHis: 0.851 ± 0.463
0.426ThrIle: 0.426 ± 0.368
2.553ThrLys: 2.553 ± 0.968
5.957ThrLeu: 5.957 ± 1.472
1.277ThrMet: 1.277 ± 0.691
1.702ThrAsn: 1.702 ± 1.061
6.809ThrPro: 6.809 ± 2.076
1.702ThrGln: 1.702 ± 1.055
4.681ThrArg: 4.681 ± 1.193
8.085ThrSer: 8.085 ± 1.539
3.404ThrThr: 3.404 ± 1.402
4.681ThrVal: 4.681 ± 0.528
0.851ThrTrp: 0.851 ± 0.948
1.702ThrTyr: 1.702 ± 0.764
0.0ThrXaa: 0.0 ± 0.0
Val
2.553ValAla: 2.553 ± 1.031
0.0ValCys: 0.0 ± 0.0
5.106ValAsp: 5.106 ± 0.874
2.979ValGlu: 2.979 ± 0.955
1.277ValPhe: 1.277 ± 0.393
3.404ValGly: 3.404 ± 1.163
1.277ValHis: 1.277 ± 1.105
5.106ValIle: 5.106 ± 2.108
5.957ValLys: 5.957 ± 1.973
4.681ValLeu: 4.681 ± 1.207
0.426ValMet: 0.426 ± 0.35
1.702ValAsn: 1.702 ± 0.274
3.83ValPro: 3.83 ± 1.385
0.851ValGln: 0.851 ± 0.421
3.83ValArg: 3.83 ± 0.687
6.809ValSer: 6.809 ± 1.438
3.404ValThr: 3.404 ± 1.313
3.404ValVal: 3.404 ± 1.209
0.851ValTrp: 0.851 ± 0.673
0.851ValTyr: 0.851 ± 0.463
0.0ValXaa: 0.0 ± 0.0
Trp
1.277TrpAla: 1.277 ± 0.691
0.426TrpCys: 0.426 ± 0.337
0.851TrpAsp: 0.851 ± 0.463
0.851TrpGlu: 0.851 ± 0.416
0.0TrpPhe: 0.0 ± 0.0
1.702TrpGly: 1.702 ± 0.574
0.851TrpHis: 0.851 ± 0.486
1.702TrpIle: 1.702 ± 0.719
0.426TrpLys: 0.426 ± 0.474
0.851TrpLeu: 0.851 ± 0.416
0.0TrpMet: 0.0 ± 0.0
0.851TrpAsn: 0.851 ± 0.486
0.851TrpPro: 0.851 ± 0.48
0.0TrpGln: 0.0 ± 0.0
0.851TrpArg: 0.851 ± 0.463
0.851TrpSer: 0.851 ± 0.486
0.851TrpThr: 0.851 ± 0.463
0.851TrpVal: 0.851 ± 0.699
0.0TrpTrp: 0.0 ± 0.0
0.426TrpTyr: 0.426 ± 0.35
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.851TyrAla: 0.851 ± 0.416
2.128TyrCys: 2.128 ± 0.936
0.851TyrAsp: 0.851 ± 0.421
2.128TyrGlu: 2.128 ± 1.464
3.404TyrPhe: 3.404 ± 0.697
1.702TyrGly: 1.702 ± 0.972
2.128TyrHis: 2.128 ± 0.721
1.702TyrIle: 1.702 ± 0.764
2.128TyrLys: 2.128 ± 1.349
2.979TyrLeu: 2.979 ± 0.893
0.851TyrMet: 0.851 ± 0.449
0.426TyrAsn: 0.426 ± 0.474
0.851TyrPro: 0.851 ± 0.419
1.277TyrGln: 1.277 ± 0.934
1.277TyrArg: 1.277 ± 0.689
1.702TyrSer: 1.702 ± 0.638
1.702TyrThr: 1.702 ± 0.615
2.553TyrVal: 2.553 ± 1.281
0.851TyrTrp: 0.851 ± 0.416
2.553TyrTyr: 2.553 ± 1.682
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2351 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski