human papillomavirus 108

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 6

Average proteome isoelectric point is 6.31

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|C0MHS1|C0MHS1_9PAPI Replication protein E1 OS=human papillomavirus 108 OX=565537 GN=E1 PE=3 SV=1
MM1 pKa = 7.71RR2 pKa = 11.84GKK4 pKa = 10.55APTIKK9 pKa = 10.73DD10 pKa = 3.02VDD12 pKa = 4.41LEE14 pKa = 4.28LHH16 pKa = 6.52SLILPEE22 pKa = 4.48NLLCGEE28 pKa = 4.15EE29 pKa = 4.14VTFEE33 pKa = 4.19KK34 pKa = 10.81EE35 pKa = 3.84EE36 pKa = 3.93QEE38 pKa = 4.36EE39 pKa = 4.07QDD41 pKa = 3.19KK42 pKa = 11.23CPYY45 pKa = 10.1RR46 pKa = 11.84VVTEE50 pKa = 4.52CGVCHH55 pKa = 7.04KK56 pKa = 9.63GLCMYY61 pKa = 10.68VLATDD66 pKa = 3.37EE67 pKa = 4.8GIRR70 pKa = 11.84GFEE73 pKa = 3.83QQLCGDD79 pKa = 4.84LDD81 pKa = 4.05IVCPACAKK89 pKa = 9.58QRR91 pKa = 11.84EE92 pKa = 4.5RR93 pKa = 11.84NGGQRR98 pKa = 11.84HH99 pKa = 4.79

Molecular weight: 11.17 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|C0MHS3|C0MHS3_9PAPI Minor capsid protein L2 OS=human papillomavirus 108 OX=565537 GN=L2 PE=3 SV=1
MM1 pKa = 6.86EE2 pKa = 4.57TLVQRR7 pKa = 11.84FDD9 pKa = 3.64VVQDD13 pKa = 3.63KK14 pKa = 11.27LLGLYY19 pKa = 8.82EE20 pKa = 4.87AGHH23 pKa = 6.8TDD25 pKa = 4.16LDD27 pKa = 3.97SQIQYY32 pKa = 9.58WDD34 pKa = 3.5LVRR37 pKa = 11.84QEE39 pKa = 4.35NVLLNFARR47 pKa = 11.84RR48 pKa = 11.84HH49 pKa = 5.71GIQMLGLQRR58 pKa = 11.84VPPLAISEE66 pKa = 4.6SKK68 pKa = 10.95AKK70 pKa = 8.47TAIMMRR76 pKa = 11.84LVLDD80 pKa = 3.97SLKK83 pKa = 10.56KK84 pKa = 10.68SPFGQEE90 pKa = 3.37PWGLTDD96 pKa = 3.83TSHH99 pKa = 6.83EE100 pKa = 4.71LYY102 pKa = 7.47TTPPEE107 pKa = 3.97NTFKK111 pKa = 11.02KK112 pKa = 10.35GGAQVEE118 pKa = 4.25VLYY121 pKa = 11.13DD122 pKa = 3.63NEE124 pKa = 4.24EE125 pKa = 4.15NKK127 pKa = 10.7AMPYY131 pKa = 9.3TKK133 pKa = 9.36WKK135 pKa = 9.49YY136 pKa = 10.31IYY138 pKa = 10.16YY139 pKa = 9.77QDD141 pKa = 5.95SEE143 pKa = 4.8DD144 pKa = 3.88LWHH147 pKa = 6.49KK148 pKa = 8.6THH150 pKa = 6.63AQVDD154 pKa = 3.83AKK156 pKa = 10.89GLYY159 pKa = 9.94FVDD162 pKa = 3.87TQMHH166 pKa = 5.38KK167 pKa = 10.14HH168 pKa = 5.99YY169 pKa = 10.49YY170 pKa = 8.43VQFDD174 pKa = 4.22KK175 pKa = 11.4EE176 pKa = 4.09AMQYY180 pKa = 7.95GHH182 pKa = 6.89KK183 pKa = 10.55GVWQVRR189 pKa = 11.84TGTDD193 pKa = 3.46TIFGASSVASTSRR206 pKa = 11.84GPDD209 pKa = 3.02ATSTDD214 pKa = 3.75PQAGRR219 pKa = 11.84LPEE222 pKa = 4.09RR223 pKa = 11.84KK224 pKa = 8.37RR225 pKa = 11.84KK226 pKa = 9.14RR227 pKa = 11.84RR228 pKa = 11.84RR229 pKa = 11.84RR230 pKa = 11.84YY231 pKa = 9.49PSTTTTATSEE241 pKa = 4.16SDD243 pKa = 3.67TEE245 pKa = 4.44EE246 pKa = 3.98STSDD250 pKa = 2.66NRR252 pKa = 11.84RR253 pKa = 11.84RR254 pKa = 11.84KK255 pKa = 9.46RR256 pKa = 11.84RR257 pKa = 11.84RR258 pKa = 11.84LRR260 pKa = 11.84EE261 pKa = 3.59RR262 pKa = 11.84KK263 pKa = 9.11HH264 pKa = 6.39RR265 pKa = 11.84SRR267 pKa = 11.84HH268 pKa = 3.75RR269 pKa = 11.84WGTGTEE275 pKa = 4.31SASDD279 pKa = 3.43TSASVGSRR287 pKa = 11.84HH288 pKa = 6.32RR289 pKa = 11.84SPNRR293 pKa = 11.84HH294 pKa = 5.19YY295 pKa = 10.44PSRR298 pKa = 11.84LARR301 pKa = 11.84LQAEE305 pKa = 4.34ARR307 pKa = 11.84DD308 pKa = 3.91PPILIVKK315 pKa = 9.76GPSNTLKK322 pKa = 10.24CWRR325 pKa = 11.84YY326 pKa = 8.85RR327 pKa = 11.84CKK329 pKa = 10.14TKK331 pKa = 11.07YY332 pKa = 10.1SGLYY336 pKa = 9.88VNISTGFTWVTGAGTEE352 pKa = 3.94GHH354 pKa = 6.51ARR356 pKa = 11.84ILVAFKK362 pKa = 11.2DD363 pKa = 3.41KK364 pKa = 9.94MQRR367 pKa = 11.84DD368 pKa = 4.0LFMQTVKK375 pKa = 10.66LPKK378 pKa = 9.53GTSCALGNLEE388 pKa = 4.65SLL390 pKa = 4.17

Molecular weight: 44.75 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

2145

99

626

429.0

47.94

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.967 ± 0.401

2.005 ± 0.808

5.874 ± 0.198

5.781 ± 1.015

3.823 ± 0.395

6.34 ± 0.561

2.238 ± 0.26

4.709 ± 0.707

5.175 ± 0.932

8.065 ± 0.786

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.678 ± 0.41

3.776 ± 0.669

6.76 ± 1.175

4.755 ± 0.117

6.014 ± 1.017

8.298 ± 0.658

7.04 ± 0.706

7.086 ± 0.682

1.399 ± 0.317

3.217 ± 0.293
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski