Candidatus Acidianus copahuensis

Taxonomy: cellular organisms; Archaea; TACK group; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae; Acidianus

Average proteome isoelectric point is 6.88

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2328 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A031LUH0|A0A031LUH0_9CREN HTH_34 domain-containing protein OS=Candidatus Acidianus copahuensis OX=1160895 GN=CM19_00175 PE=4 SV=1
MM1 pKa = 7.37YY2 pKa = 10.39SLSNVSSSADD12 pKa = 3.27LDD14 pKa = 3.75YY15 pKa = 11.68SMNMSSNFYY24 pKa = 9.55QVEE27 pKa = 3.58IRR29 pKa = 11.84EE30 pKa = 4.19FDD32 pKa = 3.62DD33 pKa = 4.0GVYY36 pKa = 10.23ISFGGEE42 pKa = 3.62PFNAEE47 pKa = 3.69SHH49 pKa = 6.67DD50 pKa = 3.98ANVQIWRR57 pKa = 11.84DD58 pKa = 2.94KK59 pKa = 10.81DD60 pKa = 3.43GRR62 pKa = 11.84IVAIDD67 pKa = 3.49IFYY70 pKa = 10.71DD71 pKa = 3.85EE72 pKa = 4.65PP73 pKa = 5.47

Molecular weight: 8.37 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A031LMP9|A0A031LMP9_9CREN GTPase OS=Candidatus Acidianus copahuensis OX=1160895 GN=CM19_08240 PE=3 SV=1
MM1 pKa = 7.38SRR3 pKa = 11.84NKK5 pKa = 10.24PSGKK9 pKa = 9.93KK10 pKa = 9.72NRR12 pKa = 11.84LGKK15 pKa = 10.56AMNSNKK21 pKa = 10.21AIPAWVILRR30 pKa = 11.84TGAKK34 pKa = 10.08LKK36 pKa = 9.8TNPLKK41 pKa = 10.96RR42 pKa = 11.84NWRR45 pKa = 11.84RR46 pKa = 11.84SKK48 pKa = 11.12LKK50 pKa = 10.42VV51 pKa = 3.04

Molecular weight: 5.84 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2328

0

2328

650260

41

1434

279.3

31.41

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.694 ± 0.049

0.636 ± 0.016

4.881 ± 0.045

6.904 ± 0.059

4.584 ± 0.046

7.029 ± 0.049

1.271 ± 0.016

9.405 ± 0.059

7.56 ± 0.06

9.824 ± 0.067

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.428 ± 0.026

4.497 ± 0.038

3.984 ± 0.034

2.109 ± 0.027

4.415 ± 0.047

7.371 ± 0.051

4.743 ± 0.042

7.341 ± 0.043

1.036 ± 0.02

4.288 ± 0.037
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski