Amino acid dipepetide frequency for Barrientosiimonas humi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.282AlaAla: 19.282 ± 0.212	0.876AlaCys: 0.876 ± 0.031	8.355AlaAsp: 8.355 ± 0.105	7.769AlaGlu: 7.769 ± 0.112	3.223AlaPhe: 3.223 ± 0.063	12.537AlaGly: 12.537 ± 0.145	2.233AlaHis: 2.233 ± 0.051	4.057AlaIle: 4.057 ± 0.076	2.632AlaLys: 2.632 ± 0.065	13.54AlaLeu: 13.54 ± 0.171	2.86AlaMet: 2.86 ± 0.055	1.793AlaAsn: 1.793 ± 0.046	6.677AlaPro: 6.677 ± 0.104	4.385AlaGln: 4.385 ± 0.068	9.829AlaArg: 9.829 ± 0.125	6.174AlaSer: 6.174 ± 0.078	7.746AlaThr: 7.746 ± 0.091	11.226AlaVal: 11.226 ± 0.129	1.933AlaTrp: 1.933 ± 0.045	2.648AlaTyr: 2.648 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.849CysAla: 0.849 ± 0.027	0.094CysCys: 0.094 ± 0.01	0.416CysAsp: 0.416 ± 0.017	0.322CysGlu: 0.322 ± 0.017	0.22CysPhe: 0.22 ± 0.015	0.764CysGly: 0.764 ± 0.028	0.152CysHis: 0.152 ± 0.012	0.183CysIle: 0.183 ± 0.013	0.081CysLys: 0.081 ± 0.009	0.632CysLeu: 0.632 ± 0.022	0.09CysMet: 0.09 ± 0.01	0.129CysAsn: 0.129 ± 0.012	0.439CysPro: 0.439 ± 0.022	0.175CysGln: 0.175 ± 0.012	0.478CysArg: 0.478 ± 0.02	0.38CysSer: 0.38 ± 0.018	0.415CysThr: 0.415 ± 0.017	0.562CysVal: 0.562 ± 0.023	0.105CysTrp: 0.105 ± 0.009	0.154CysTyr: 0.154 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.995AspAla: 7.995 ± 0.088	0.303AspCys: 0.303 ± 0.018	5.02AspAsp: 5.02 ± 0.089	4.597AspGlu: 4.597 ± 0.078	1.506AspPhe: 1.506 ± 0.036	6.184AspGly: 6.184 ± 0.071	1.352AspHis: 1.352 ± 0.035	1.768AspIle: 1.768 ± 0.046	1.214AspLys: 1.214 ± 0.041	7.168AspLeu: 7.168 ± 0.096	0.834AspMet: 0.834 ± 0.027	1.041AspAsn: 1.041 ± 0.033	4.787AspPro: 4.787 ± 0.077	2.098AspGln: 2.098 ± 0.047	5.164AspArg: 5.164 ± 0.097	2.605AspSer: 2.605 ± 0.049	2.822AspThr: 2.822 ± 0.049	5.867AspVal: 5.867 ± 0.099	0.935AspTrp: 0.935 ± 0.032	1.245AspTyr: 1.245 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	6.78GluAla: 6.78 ± 0.086	0.31GluCys: 0.31 ± 0.016	2.565GluAsp: 2.565 ± 0.053	3.112GluGlu: 3.112 ± 0.069	1.373GluPhe: 1.373 ± 0.036	4.388GluGly: 4.388 ± 0.065	1.647GluHis: 1.647 ± 0.044	2.17GluIle: 2.17 ± 0.047	1.169GluLys: 1.169 ± 0.04	6.644GluLeu: 6.644 ± 0.101	0.98GluMet: 0.98 ± 0.033	0.814GluAsn: 0.814 ± 0.028	3.661GluPro: 3.661 ± 0.068	3.221GluGln: 3.221 ± 0.049	5.889GluArg: 5.889 ± 0.091	2.746GluSer: 2.746 ± 0.05	2.978GluThr: 2.978 ± 0.053	5.199GluVal: 5.199 ± 0.071	0.773GluTrp: 0.773 ± 0.028	0.718GluTyr: 0.718 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	3.548PheAla: 3.548 ± 0.065	0.217PheCys: 0.217 ± 0.016	1.965PheAsp: 1.965 ± 0.05	1.451PheGlu: 1.451 ± 0.037	0.939PhePhe: 0.939 ± 0.036	2.957PheGly: 2.957 ± 0.052	0.495PheHis: 0.495 ± 0.02	0.623PheIle: 0.623 ± 0.026	0.403PheLys: 0.403 ± 0.022	2.442PheLeu: 2.442 ± 0.052	0.377PheMet: 0.377 ± 0.019	0.541PheAsn: 0.541 ± 0.024	1.298PhePro: 1.298 ± 0.035	0.64PheGln: 0.64 ± 0.021	1.689PheArg: 1.689 ± 0.038	1.463PheSer: 1.463 ± 0.04	1.763PheThr: 1.763 ± 0.038	2.662PheVal: 2.662 ± 0.061	0.455PheTrp: 0.455 ± 0.024	0.529PheTyr: 0.529 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	10.852GlyAla: 10.852 ± 0.112	0.705GlyCys: 0.705 ± 0.026	5.609GlyAsp: 5.609 ± 0.082	5.485GlyGlu: 5.485 ± 0.08	2.923GlyPhe: 2.923 ± 0.056	8.469GlyGly: 8.469 ± 0.122	1.858GlyHis: 1.858 ± 0.051	3.519GlyIle: 3.519 ± 0.058	2.254GlyLys: 2.254 ± 0.056	9.367GlyLeu: 9.367 ± 0.119	2.08GlyMet: 2.08 ± 0.043	1.639GlyAsn: 1.639 ± 0.046	4.688GlyPro: 4.688 ± 0.075	3.258GlyGln: 3.258 ± 0.087	7.509GlyArg: 7.509 ± 0.081	5.776GlySer: 5.776 ± 0.092	5.401GlyThr: 5.401 ± 0.088	8.017GlyVal: 8.017 ± 0.094	1.75GlyTrp: 1.75 ± 0.042	2.112GlyTyr: 2.112 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	2.338HisAla: 2.338 ± 0.047	0.153HisCys: 0.153 ± 0.011	1.6HisAsp: 1.6 ± 0.04	1.283HisGlu: 1.283 ± 0.035	0.48HisPhe: 0.48 ± 0.021	1.998HisGly: 1.998 ± 0.045	0.601HisHis: 0.601 ± 0.026	0.452HisIle: 0.452 ± 0.019	0.295HisLys: 0.295 ± 0.017	2.215HisLeu: 2.215 ± 0.047	0.227HisMet: 0.227 ± 0.015	0.32HisAsn: 0.32 ± 0.016	1.548HisPro: 1.548 ± 0.038	0.611HisGln: 0.611 ± 0.023	1.74HisArg: 1.74 ± 0.044	0.791HisSer: 0.791 ± 0.029	1.014HisThr: 1.014 ± 0.03	1.756HisVal: 1.756 ± 0.05	0.283HisTrp: 0.283 ± 0.015	0.4HisTyr: 0.4 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	4.53IleAla: 4.53 ± 0.07	0.296IleCys: 0.296 ± 0.017	2.576IleAsp: 2.576 ± 0.044	2.037IleGlu: 2.037 ± 0.048	0.934IlePhe: 0.934 ± 0.03	3.548IleGly: 3.548 ± 0.054	0.567IleHis: 0.567 ± 0.027	0.9IleIle: 0.9 ± 0.03	0.727IleLys: 0.727 ± 0.03	2.34IleLeu: 2.34 ± 0.05	0.456IleMet: 0.456 ± 0.019	0.7IleAsn: 0.7 ± 0.03	1.686IlePro: 1.686 ± 0.041	0.739IleGln: 0.739 ± 0.026	2.051IleArg: 2.051 ± 0.042	1.759IleSer: 1.759 ± 0.044	2.282IleThr: 2.282 ± 0.051	3.142IleVal: 3.142 ± 0.061	0.35IleTrp: 0.35 ± 0.016	0.604IleTyr: 0.604 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.42LysAla: 2.42 ± 0.06	0.083LysCys: 0.083 ± 0.009	1.154LysAsp: 1.154 ± 0.041	0.929LysGlu: 0.929 ± 0.029	0.455LysPhe: 0.455 ± 0.025	1.639LysGly: 1.639 ± 0.048	0.42LysHis: 0.42 ± 0.02	0.771LysIle: 0.771 ± 0.026	0.767LysLys: 0.767 ± 0.044	1.602LysLeu: 1.602 ± 0.043	0.339LysMet: 0.339 ± 0.019	0.453LysAsn: 0.453 ± 0.022	1.231LysPro: 1.231 ± 0.045	0.772LysGln: 0.772 ± 0.029	1.328LysArg: 1.328 ± 0.043	1.094LysSer: 1.094 ± 0.041	1.196LysThr: 1.196 ± 0.035	1.897LysVal: 1.897 ± 0.058	0.194LysTrp: 0.194 ± 0.012	0.422LysTyr: 0.422 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.911LeuAla: 14.911 ± 0.169	0.64LeuCys: 0.64 ± 0.027	6.991LeuAsp: 6.991 ± 0.108	5.199LeuGlu: 5.199 ± 0.077	2.233LeuPhe: 2.233 ± 0.05	9.844LeuGly: 9.844 ± 0.117	1.943LeuHis: 1.943 ± 0.042	2.967LeuIle: 2.967 ± 0.058	1.563LeuLys: 1.563 ± 0.05	11.446LeuLeu: 11.446 ± 0.149	1.607LeuMet: 1.607 ± 0.045	1.473LeuAsn: 1.473 ± 0.034	6.039LeuPro: 6.039 ± 0.076	2.809LeuGln: 2.809 ± 0.051	8.63LeuArg: 8.63 ± 0.12	5.166LeuSer: 5.166 ± 0.072	6.441LeuThr: 6.441 ± 0.076	10.394LeuVal: 10.394 ± 0.13	1.234LeuTrp: 1.234 ± 0.037	1.404LeuTyr: 1.404 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.243MetAla: 2.243 ± 0.043	0.145MetCys: 0.145 ± 0.012	0.761MetAsp: 0.761 ± 0.026	0.644MetGlu: 0.644 ± 0.025	0.504MetPhe: 0.504 ± 0.023	1.384MetGly: 1.384 ± 0.039	0.376MetHis: 0.376 ± 0.019	0.706MetIle: 0.706 ± 0.029	0.398MetLys: 0.398 ± 0.019	1.949MetLeu: 1.949 ± 0.041	0.271MetMet: 0.271 ± 0.017	0.396MetAsn: 0.396 ± 0.02	1.146MetPro: 1.146 ± 0.033	0.552MetGln: 0.552 ± 0.024	1.435MetArg: 1.435 ± 0.039	1.663MetSer: 1.663 ± 0.04	1.721MetThr: 1.721 ± 0.042	1.462MetVal: 1.462 ± 0.037	0.193MetTrp: 0.193 ± 0.014	0.269MetTyr: 0.269 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.053AsnAla: 2.053 ± 0.048	0.122AsnCys: 0.122 ± 0.011	0.984AsnAsp: 0.984 ± 0.032	0.749AsnGlu: 0.749 ± 0.025	0.462AsnPhe: 0.462 ± 0.02	1.519AsnGly: 1.519 ± 0.044	0.345AsnHis: 0.345 ± 0.019	0.566AsnIle: 0.566 ± 0.024	0.368AsnLys: 0.368 ± 0.019	1.752AsnLeu: 1.752 ± 0.043	0.255AsnMet: 0.255 ± 0.018	0.391AsnAsn: 0.391 ± 0.018	1.447AsnPro: 1.447 ± 0.036	0.534AsnGln: 0.534 ± 0.025	1.191AsnArg: 1.191 ± 0.038	0.757AsnSer: 0.757 ± 0.028	0.884AsnThr: 0.884 ± 0.032	1.463AsnVal: 1.463 ± 0.034	0.216AsnTrp: 0.216 ± 0.016	0.38AsnTyr: 0.38 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.849ProAla: 7.849 ± 0.108	0.264ProCys: 0.264 ± 0.015	4.591ProAsp: 4.591 ± 0.066	4.221ProGlu: 4.221 ± 0.068	1.503ProPhe: 1.503 ± 0.039	6.248ProGly: 6.248 ± 0.097	1.174ProHis: 1.174 ± 0.031	1.622ProIle: 1.622 ± 0.037	1.078ProLys: 1.078 ± 0.039	4.952ProLeu: 4.952 ± 0.068	1.078ProMet: 1.078 ± 0.028	0.841ProAsn: 0.841 ± 0.032	3.139ProPro: 3.139 ± 0.072	2.25ProGln: 2.25 ± 0.051	4.054ProArg: 4.054 ± 0.069	3.291ProSer: 3.291 ± 0.068	3.886ProThr: 3.886 ± 0.067	5.396ProVal: 5.396 ± 0.072	0.94ProTrp: 0.94 ± 0.029	1.102ProTyr: 1.102 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.165GlnAla: 4.165 ± 0.065	0.173GlnCys: 0.173 ± 0.012	1.423GlnAsp: 1.423 ± 0.038	1.58GlnGlu: 1.58 ± 0.044	0.727GlnPhe: 0.727 ± 0.027	2.732GlnGly: 2.732 ± 0.063	0.846GlnHis: 0.846 ± 0.027	1.281GlnIle: 1.281 ± 0.033	0.489GlnLys: 0.489 ± 0.02	3.739GlnLeu: 3.739 ± 0.065	0.563GlnMet: 0.563 ± 0.021	0.513GlnAsn: 0.513 ± 0.023	2.249GlnPro: 2.249 ± 0.059	1.925GlnGln: 1.925 ± 0.058	3.122GlnArg: 3.122 ± 0.053	1.36GlnSer: 1.36 ± 0.042	1.779GlnThr: 1.779 ± 0.04	3.568GlnVal: 3.568 ± 0.06	0.49GlnTrp: 0.49 ± 0.022	0.471GlnTyr: 0.471 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	9.529ArgAla: 9.529 ± 0.107	0.52ArgCys: 0.52 ± 0.022	5.05ArgAsp: 5.05 ± 0.08	5.095ArgGlu: 5.095 ± 0.088	2.299ArgPhe: 2.299 ± 0.055	6.12ArgGly: 6.12 ± 0.082	1.718ArgHis: 1.718 ± 0.047	2.812ArgIle: 2.812 ± 0.054	1.443ArgLys: 1.443 ± 0.037	8.484ArgLeu: 8.484 ± 0.11	1.78ArgMet: 1.78 ± 0.041	1.216ArgAsn: 1.216 ± 0.036	4.939ArgPro: 4.939 ± 0.084	2.443ArgGln: 2.443 ± 0.056	7.817ArgArg: 7.817 ± 0.106	4.503ArgSer: 4.503 ± 0.065	5.024ArgThr: 5.024 ± 0.073	6.545ArgVal: 6.545 ± 0.088	1.437ArgTrp: 1.437 ± 0.04	1.534ArgTyr: 1.534 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.56SerAla: 6.56 ± 0.094	0.344SerCys: 0.344 ± 0.018	3.227SerAsp: 3.227 ± 0.061	2.479SerGlu: 2.479 ± 0.053	1.575SerPhe: 1.575 ± 0.04	5.864SerGly: 5.864 ± 0.093	0.862SerHis: 0.862 ± 0.027	1.745SerIle: 1.745 ± 0.044	1.0SerLys: 1.0 ± 0.038	4.943SerLeu: 4.943 ± 0.074	1.28SerMet: 1.28 ± 0.036	0.941SerAsn: 0.941 ± 0.029	3.299SerPro: 3.299 ± 0.061	1.485SerGln: 1.485 ± 0.038	3.853SerArg: 3.853 ± 0.069	3.312SerSer: 3.312 ± 0.08	3.649SerThr: 3.649 ± 0.069	4.338SerVal: 4.338 ± 0.072	0.952SerTrp: 0.952 ± 0.031	1.185SerTyr: 1.185 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	7.349ThrAla: 7.349 ± 0.1	0.425ThrCys: 0.425 ± 0.024	3.865ThrAsp: 3.865 ± 0.048	3.064ThrGlu: 3.064 ± 0.057	1.757ThrPhe: 1.757 ± 0.039	6.141ThrGly: 6.141 ± 0.089	1.142ThrHis: 1.142 ± 0.032	2.145ThrIle: 2.145 ± 0.045	1.147ThrLys: 1.147 ± 0.043	5.808ThrLeu: 5.808 ± 0.064	1.114ThrMet: 1.114 ± 0.03	1.065ThrAsn: 1.065 ± 0.037	4.126ThrPro: 4.126 ± 0.076	1.62ThrGln: 1.62 ± 0.043	4.17ThrArg: 4.17 ± 0.066	3.566ThrSer: 3.566 ± 0.066	4.096ThrThr: 4.096 ± 0.071	5.754ThrVal: 5.754 ± 0.081	1.006ThrTrp: 1.006 ± 0.031	1.491ThrTyr: 1.491 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	12.233ValAla: 12.233 ± 0.122	0.68ValCys: 0.68 ± 0.025	5.974ValAsp: 5.974 ± 0.081	5.58ValGlu: 5.58 ± 0.073	2.242ValPhe: 2.242 ± 0.048	7.981ValGly: 7.981 ± 0.096	1.736ValHis: 1.736 ± 0.04	3.001ValIle: 3.001 ± 0.055	1.553ValLys: 1.553 ± 0.052	10.045ValLeu: 10.045 ± 0.127	1.514ValMet: 1.514 ± 0.039	1.523ValAsn: 1.523 ± 0.035	5.249ValPro: 5.249 ± 0.072	2.566ValGln: 2.566 ± 0.051	7.467ValArg: 7.467 ± 0.088	4.63ValSer: 4.63 ± 0.068	5.889ValThr: 5.889 ± 0.074	10.209ValVal: 10.209 ± 0.12	1.229ValTrp: 1.229 ± 0.035	1.313ValTyr: 1.313 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.602TrpAla: 1.602 ± 0.045	0.146TrpCys: 0.146 ± 0.011	0.813TrpAsp: 0.813 ± 0.03	0.643TrpGlu: 0.643 ± 0.023	0.55TrpPhe: 0.55 ± 0.025	1.114TrpGly: 1.114 ± 0.035	0.333TrpHis: 0.333 ± 0.019	0.536TrpIle: 0.536 ± 0.024	0.282TrpLys: 0.282 ± 0.016	1.835TrpLeu: 1.835 ± 0.042	0.318TrpMet: 0.318 ± 0.018	0.313TrpAsn: 0.313 ± 0.02	0.814TrpPro: 0.814 ± 0.029	0.622TrpGln: 0.622 ± 0.023	1.367TrpArg: 1.367 ± 0.037	1.028TrpSer: 1.028 ± 0.033	0.913TrpThr: 0.913 ± 0.029	1.294TrpVal: 1.294 ± 0.039	0.41TrpTrp: 0.41 ± 0.023	0.24TrpTyr: 0.24 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.685TyrAla: 2.685 ± 0.05	0.143TyrCys: 0.143 ± 0.011	1.567TyrAsp: 1.567 ± 0.04	0.9TyrGlu: 0.9 ± 0.033	0.552TyrPhe: 0.552 ± 0.023	1.841TyrGly: 1.841 ± 0.05	0.305TyrHis: 0.305 ± 0.017	0.402TyrIle: 0.402 ± 0.022	0.301TyrLys: 0.301 ± 0.017	2.029TyrLeu: 2.029 ± 0.04	0.194TyrMet: 0.194 ± 0.013	0.34TyrAsn: 0.34 ± 0.016	1.017TyrPro: 1.017 ± 0.035	0.489TyrGln: 0.489 ± 0.025	1.524TyrArg: 1.524 ± 0.036	0.828TyrSer: 0.828 ± 0.031	0.953TyrThr: 0.953 ± 0.032	1.863TyrVal: 1.863 ± 0.04	0.289TyrTrp: 0.289 ± 0.017	0.406TyrTyr: 0.406 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3329 proteins (1100107 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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