Amino acid dipepetide frequency for Piscine myocarditis virus AL V-708

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.475AlaAla: 8.475 ± 5.643
0.0AlaCys: 0.0 ± 0.0
4.767AlaAsp: 4.767 ± 2.01
6.356AlaGlu: 6.356 ± 0.4
2.648AlaPhe: 2.648 ± 1.175
7.945AlaGly: 7.945 ± 2.753
2.119AlaHis: 2.119 ± 0.838
1.589AlaIle: 1.589 ± 0.488
4.767AlaLys: 4.767 ± 2.318
7.415AlaLeu: 7.415 ± 1.332
3.708AlaMet: 3.708 ± 2.469
2.648AlaAsn: 2.648 ± 1.175
1.589AlaPro: 1.589 ± 1.058
4.237AlaGln: 4.237 ± 1.675
4.767AlaArg: 4.767 ± 1.889
3.708AlaSer: 3.708 ± 1.551
3.708AlaThr: 3.708 ± 1.209
7.415AlaVal: 7.415 ± 4.938
1.589AlaTrp: 1.589 ± 0.521
0.53AlaTyr: 0.53 ± 0.353
0.0AlaXaa: 0.0 ± 0.0
Cys
0.53CysAla: 0.53 ± 0.396
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.648CysGly: 2.648 ± 1.208
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.059CysLys: 1.059 ± 1.556
2.119CysLeu: 2.119 ± 2.232
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.53CysPro: 0.53 ± 0.353
0.53CysGln: 0.53 ± 0.778
2.119CysArg: 2.119 ± 0.599
1.059CysSer: 1.059 ± 0.793
1.589CysThr: 1.589 ± 1.471
2.119CysVal: 2.119 ± 0.556
0.0CysTrp: 0.0 ± 0.0
1.059CysTyr: 1.059 ± 0.744
0.0CysXaa: 0.0 ± 0.0
Asp
2.648AspAla: 2.648 ± 0.224
0.0AspCys: 0.0 ± 0.0
3.708AspAsp: 3.708 ± 1.349
2.119AspGlu: 2.119 ± 0.413
0.53AspPhe: 0.53 ± 0.353
1.059AspGly: 1.059 ± 0.793
0.0AspHis: 0.0 ± 0.0
1.589AspIle: 1.589 ± 0.488
1.589AspLys: 1.589 ± 0.904
4.237AspLeu: 4.237 ± 0.698
2.648AspMet: 2.648 ± 0.594
4.237AspAsn: 4.237 ± 1.6
1.589AspPro: 1.589 ± 0.521
0.53AspGln: 0.53 ± 0.353
4.767AspArg: 4.767 ± 1.562
2.648AspSer: 2.648 ± 1.208
1.589AspThr: 1.589 ± 1.058
4.767AspVal: 4.767 ± 2.01
2.119AspTrp: 2.119 ± 0.599
1.589AspTyr: 1.589 ± 0.608
0.0AspXaa: 0.0 ± 0.0
Glu
5.297GluAla: 5.297 ± 0.576
0.53GluCys: 0.53 ± 0.353
2.648GluAsp: 2.648 ± 1.175
6.356GluGlu: 6.356 ± 3.541
2.648GluPhe: 2.648 ± 1.208
10.064GluGly: 10.064 ± 3.009
2.648GluHis: 2.648 ± 1.132
3.178GluIle: 3.178 ± 1.807
2.648GluLys: 2.648 ± 1.208
4.237GluLeu: 4.237 ± 1.112
2.119GluMet: 2.119 ± 0.413
3.178GluAsn: 3.178 ± 0.899
4.237GluPro: 4.237 ± 1.6
1.059GluGln: 1.059 ± 0.3
5.826GluArg: 5.826 ± 2.433
3.708GluSer: 3.708 ± 0.833
1.589GluThr: 1.589 ± 1.189
5.826GluVal: 5.826 ± 1.736
1.059GluTrp: 1.059 ± 0.744
3.708GluTyr: 3.708 ± 1.583
0.0GluXaa: 0.0 ± 0.0
Phe
1.059PheAla: 1.059 ± 0.3
0.0PheCys: 0.0 ± 0.0
2.648PheAsp: 2.648 ± 0.224
1.589PheGlu: 1.589 ± 0.904
1.059PhePhe: 1.059 ± 0.694
2.119PheGly: 2.119 ± 0.413
0.53PheHis: 0.53 ± 0.778
0.53PheIle: 0.53 ± 0.396
1.589PheLys: 1.589 ± 1.189
2.119PheLeu: 2.119 ± 0.413
1.059PheMet: 1.059 ± 0.744
1.059PheAsn: 1.059 ± 0.694
1.589PhePro: 1.589 ± 1.058
0.53PheGln: 0.53 ± 0.396
2.648PheArg: 2.648 ± 1.132
1.589PheSer: 1.589 ± 0.521
1.059PheThr: 1.059 ± 0.3
1.589PheVal: 1.589 ± 1.058
1.589PheTrp: 1.589 ± 1.058
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
8.475GlyAla: 8.475 ± 3.868
2.119GlyCys: 2.119 ± 1.489
2.119GlyAsp: 2.119 ± 0.599
6.886GlyGlu: 6.886 ± 0.667
3.708GlyPhe: 3.708 ± 1.813
16.419GlyGly: 16.419 ± 3.65
0.53GlyHis: 0.53 ± 0.778
3.178GlyIle: 3.178 ± 1.102
9.004GlyLys: 9.004 ± 3.375
6.356GlyLeu: 6.356 ± 1.797
2.119GlyMet: 2.119 ± 1.411
5.826GlyAsn: 5.826 ± 2.076
4.237GlyPro: 4.237 ± 2.216
3.708GlyGln: 3.708 ± 1.209
3.178GlyArg: 3.178 ± 0.2
4.237GlySer: 4.237 ± 0.827
4.237GlyThr: 4.237 ± 1.675
7.415GlyVal: 7.415 ± 2.177
4.237GlyTrp: 4.237 ± 1.198
5.297GlyTyr: 5.297 ± 0.806
0.0GlyXaa: 0.0 ± 0.0
His
0.53HisAla: 0.53 ± 0.353
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.53HisGlu: 0.53 ± 0.778
0.53HisPhe: 0.53 ± 0.353
0.0HisGly: 0.0 ± 0.0
0.53HisHis: 0.53 ± 0.353
0.53HisIle: 0.53 ± 0.778
1.589HisLys: 1.589 ± 0.608
2.119HisLeu: 2.119 ± 2.198
0.53HisMet: 0.53 ± 0.353
0.53HisAsn: 0.53 ± 0.396
0.0HisPro: 0.0 ± 0.0
0.53HisGln: 0.53 ± 0.396
1.589HisArg: 1.589 ± 0.608
1.059HisSer: 1.059 ± 0.3
0.53HisThr: 0.53 ± 0.353
1.059HisVal: 1.059 ± 0.694
1.059HisTrp: 1.059 ± 0.705
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.648IleAla: 2.648 ± 0.594
0.0IleCys: 0.0 ± 0.0
3.178IleAsp: 3.178 ± 1.279
3.178IleGlu: 3.178 ± 1.955
0.53IlePhe: 0.53 ± 0.396
5.297IleGly: 5.297 ± 0.806
0.0IleHis: 0.0 ± 0.0
2.119IleIle: 2.119 ± 0.556
6.356IleLys: 6.356 ± 3.49
3.178IleLeu: 3.178 ± 1.18
1.059IleMet: 1.059 ± 0.343
3.708IleAsn: 3.708 ± 1.458
0.53IlePro: 0.53 ± 0.353
1.059IleGln: 1.059 ± 0.694
4.767IleArg: 4.767 ± 1.443
2.119IleSer: 2.119 ± 1.585
3.178IleThr: 3.178 ± 1.18
4.767IleVal: 4.767 ± 3.327
0.53IleTrp: 0.53 ± 0.353
0.53IleTyr: 0.53 ± 0.396
0.0IleXaa: 0.0 ± 0.0
Lys
2.648LysAla: 2.648 ± 1.368
1.059LysCys: 1.059 ± 0.744
1.059LysAsp: 1.059 ± 0.744
2.648LysGlu: 2.648 ± 1.608
0.53LysPhe: 0.53 ± 0.396
3.708LysGly: 3.708 ± 1.813
0.0LysHis: 0.0 ± 0.0
5.297LysIle: 5.297 ± 1.007
4.237LysLys: 4.237 ± 3.49
3.178LysLeu: 3.178 ± 1.868
1.589LysMet: 1.589 ± 0.904
2.119LysAsn: 2.119 ± 1.18
1.059LysPro: 1.059 ± 0.793
0.0LysGln: 0.0 ± 0.0
5.826LysArg: 5.826 ± 2.608
5.297LysSer: 5.297 ± 2.341
1.589LysThr: 1.589 ± 0.904
7.415LysVal: 7.415 ± 1.785
1.059LysTrp: 1.059 ± 0.793
1.589LysTyr: 1.589 ± 0.904
0.0LysXaa: 0.0 ± 0.0
Leu
6.356LeuAla: 6.356 ± 1.127
4.767LeuCys: 4.767 ± 2.689
3.708LeuAsp: 3.708 ± 1.154
4.237LeuGlu: 4.237 ± 2.018
1.059LeuPhe: 1.059 ± 0.694
8.475LeuGly: 8.475 ± 2.596
0.53LeuHis: 0.53 ± 0.353
4.237LeuIle: 4.237 ± 2.528
2.119LeuLys: 2.119 ± 1.585
5.297LeuLeu: 5.297 ± 1.666
1.059LeuMet: 1.059 ± 0.705
3.708LeuAsn: 3.708 ± 1.05
5.297LeuPro: 5.297 ± 1.187
0.53LeuGln: 0.53 ± 0.396
6.886LeuArg: 6.886 ± 2.578
4.767LeuSer: 4.767 ± 1.645
2.119LeuThr: 2.119 ± 0.556
5.826LeuVal: 5.826 ± 3.015
1.589LeuTrp: 1.589 ± 0.608
2.648LeuTyr: 2.648 ± 0.224
0.0LeuXaa: 0.0 ± 0.0
Met
3.178MetAla: 3.178 ± 1.519
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.589MetGlu: 1.589 ± 0.521
0.53MetPhe: 0.53 ± 0.778
3.708MetGly: 3.708 ± 1.182
0.0MetHis: 0.0 ± 0.0
2.119MetIle: 2.119 ± 1.585
1.589MetLys: 1.589 ± 0.904
2.119MetLeu: 2.119 ± 0.99
2.119MetMet: 2.119 ± 0.599
3.178MetAsn: 3.178 ± 2.116
0.53MetPro: 0.53 ± 0.396
0.53MetGln: 0.53 ± 0.353
4.237MetArg: 4.237 ± 1.546
2.648MetSer: 2.648 ± 0.224
0.53MetThr: 0.53 ± 0.353
3.178MetVal: 3.178 ± 0.899
0.53MetTrp: 0.53 ± 0.396
0.53MetTyr: 0.53 ± 0.353
0.0MetXaa: 0.0 ± 0.0
Asn
4.237AsnAla: 4.237 ± 0.875
0.0AsnCys: 0.0 ± 0.0
3.178AsnAsp: 3.178 ± 0.976
3.178AsnGlu: 3.178 ± 0.2
1.059AsnPhe: 1.059 ± 0.705
3.178AsnGly: 3.178 ± 1.557
1.589AsnHis: 1.589 ± 0.608
2.119AsnIle: 2.119 ± 0.556
1.059AsnLys: 1.059 ± 0.694
4.237AsnLeu: 4.237 ± 1.112
0.53AsnMet: 0.53 ± 0.353
0.0AsnAsn: 0.0 ± 0.0
2.648AsnPro: 2.648 ± 0.594
2.119AsnGln: 2.119 ± 0.413
2.648AsnArg: 2.648 ± 0.773
3.708AsnSer: 3.708 ± 2.065
5.297AsnThr: 5.297 ± 1.187
1.589AsnVal: 1.589 ± 0.778
2.648AsnTrp: 2.648 ± 1.368
0.53AsnTyr: 0.53 ± 0.353
0.0AsnXaa: 0.0 ± 0.0
Pro
5.826ProAla: 5.826 ± 1.312
1.059ProCys: 1.059 ± 0.3
1.589ProAsp: 1.589 ± 0.778
2.648ProGlu: 2.648 ± 1.432
2.119ProPhe: 2.119 ± 0.599
5.826ProGly: 5.826 ± 1.929
0.0ProHis: 0.0 ± 0.0
1.059ProIle: 1.059 ± 0.705
1.059ProLys: 1.059 ± 0.793
6.886ProLeu: 6.886 ± 0.716
0.53ProMet: 0.53 ± 0.778
1.589ProAsn: 1.589 ± 0.521
2.119ProPro: 2.119 ± 0.413
0.0ProGln: 0.0 ± 0.0
1.059ProArg: 1.059 ± 0.744
1.059ProSer: 1.059 ± 0.705
3.178ProThr: 3.178 ± 0.899
3.178ProVal: 3.178 ± 1.042
1.059ProTrp: 1.059 ± 0.705
1.059ProTyr: 1.059 ± 0.694
0.0ProXaa: 0.0 ± 0.0
Gln
2.119GlnAla: 2.119 ± 0.838
0.53GlnCys: 0.53 ± 0.778
1.059GlnAsp: 1.059 ± 0.694
1.589GlnGlu: 1.589 ± 0.904
0.0GlnPhe: 0.0 ± 0.0
3.708GlnGly: 3.708 ± 1.349
0.53GlnHis: 0.53 ± 0.778
1.059GlnIle: 1.059 ± 0.793
1.589GlnLys: 1.589 ± 0.608
0.53GlnLeu: 0.53 ± 0.353
2.648GlnMet: 2.648 ± 0.727
1.589GlnAsn: 1.589 ± 0.521
1.589GlnPro: 1.589 ± 1.058
1.589GlnGln: 1.589 ± 0.521
2.648GlnArg: 2.648 ± 0.224
1.589GlnSer: 1.589 ± 1.432
3.708GlnThr: 3.708 ± 1.349
1.589GlnVal: 1.589 ± 0.608
0.53GlnTrp: 0.53 ± 0.353
1.059GlnTyr: 1.059 ± 0.705
0.0GlnXaa: 0.0 ± 0.0
Arg
7.945ArgAla: 7.945 ± 3.981
1.589ArgCys: 1.589 ± 0.608
3.178ArgAsp: 3.178 ± 0.493
10.064ArgGlu: 10.064 ± 1.252
3.178ArgPhe: 3.178 ± 1.215
5.297ArgGly: 5.297 ± 0.563
0.0ArgHis: 0.0 ± 0.0
5.297ArgIle: 5.297 ± 1.744
1.059ArgLys: 1.059 ± 0.3
3.708ArgLeu: 3.708 ± 0.204
1.589ArgMet: 1.589 ± 0.608
1.059ArgAsn: 1.059 ± 0.744
3.708ArgPro: 3.708 ± 0.866
2.648ArgGln: 2.648 ± 1.511
3.708ArgArg: 3.708 ± 1.813
2.648ArgSer: 2.648 ± 0.773
3.178ArgThr: 3.178 ± 0.493
5.826ArgVal: 5.826 ± 0.792
3.178ArgTrp: 3.178 ± 1.18
1.059ArgTyr: 1.059 ± 0.3
0.0ArgXaa: 0.0 ± 0.0
Ser
2.648SerAla: 2.648 ± 0.594
0.53SerCys: 0.53 ± 0.396
2.648SerAsp: 2.648 ± 1.511
3.708SerGlu: 3.708 ± 1.551
2.119SerPhe: 2.119 ± 1.264
7.415SerGly: 7.415 ± 1.054
0.53SerHis: 0.53 ± 0.778
4.237SerIle: 4.237 ± 1.962
1.589SerLys: 1.589 ± 0.904
4.237SerLeu: 4.237 ± 1.284
3.178SerMet: 3.178 ± 1.042
3.708SerAsn: 3.708 ± 0.968
2.119SerPro: 2.119 ± 0.413
2.119SerGln: 2.119 ± 1.18
3.708SerArg: 3.708 ± 1.583
2.119SerSer: 2.119 ± 0.99
1.059SerThr: 1.059 ± 0.3
7.945SerVal: 7.945 ± 0.368
1.059SerTrp: 1.059 ± 0.3
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.237ThrAla: 4.237 ± 1.546
1.059ThrCys: 1.059 ± 0.744
1.059ThrAsp: 1.059 ± 0.705
4.237ThrGlu: 4.237 ± 0.297
0.0ThrPhe: 0.0 ± 0.0
2.648ThrGly: 2.648 ± 0.773
1.059ThrHis: 1.059 ± 0.705
3.708ThrIle: 3.708 ± 1.458
2.119ThrLys: 2.119 ± 1.585
2.648ThrLeu: 2.648 ± 0.224
2.119ThrMet: 2.119 ± 0.838
2.648ThrAsn: 2.648 ± 0.594
2.119ThrPro: 2.119 ± 0.599
2.648ThrGln: 2.648 ± 0.594
2.119ThrArg: 2.119 ± 0.599
4.767ThrSer: 4.767 ± 1.443
5.826ThrThr: 5.826 ± 1.8
4.767ThrVal: 4.767 ± 1.337
1.589ThrTrp: 1.589 ± 0.904
0.53ThrTyr: 0.53 ± 0.778
0.0ThrXaa: 0.0 ± 0.0
Val
9.534ValAla: 9.534 ± 3.125
0.53ValCys: 0.53 ± 0.353
3.708ValAsp: 3.708 ± 1.895
8.475ValGlu: 8.475 ± 1.386
3.178ValPhe: 3.178 ± 0.899
7.945ValGly: 7.945 ± 2.938
1.059ValHis: 1.059 ± 0.3
4.767ValIle: 4.767 ± 0.534
3.708ValLys: 3.708 ± 0.833
5.826ValLeu: 5.826 ± 2.004
1.589ValMet: 1.589 ± 0.935
4.237ValAsn: 4.237 ± 0.875
6.886ValPro: 6.886 ± 0.716
3.708ValGln: 3.708 ± 1.867
6.356ValArg: 6.356 ± 1.663
4.767ValSer: 4.767 ± 1.443
4.237ValThr: 4.237 ± 1.254
6.886ValVal: 6.886 ± 2.089
0.53ValTrp: 0.53 ± 0.353
1.059ValTyr: 1.059 ± 0.3
0.0ValXaa: 0.0 ± 0.0
Trp
1.059TrpAla: 1.059 ± 0.3
1.059TrpCys: 1.059 ± 1.556
2.119TrpAsp: 2.119 ± 0.838
2.648TrpGlu: 2.648 ± 1.368
0.53TrpPhe: 0.53 ± 0.353
3.178TrpGly: 3.178 ± 1.519
0.53TrpHis: 0.53 ± 0.353
1.059TrpIle: 1.059 ± 0.793
1.589TrpLys: 1.589 ± 0.904
2.119TrpLeu: 2.119 ± 1.585
1.589TrpMet: 1.589 ± 1.189
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.059TrpGln: 1.059 ± 0.3
0.53TrpArg: 0.53 ± 0.396
1.589TrpSer: 1.589 ± 1.058
2.648TrpThr: 2.648 ± 0.872
3.178TrpVal: 3.178 ± 1.042
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.53TyrAla: 0.53 ± 0.353
0.53TyrCys: 0.53 ± 0.778
1.589TyrAsp: 1.589 ± 0.488
0.53TyrGlu: 0.53 ± 0.396
0.0TyrPhe: 0.0 ± 0.0
2.648TyrGly: 2.648 ± 0.872
1.059TyrHis: 1.059 ± 0.793
1.059TyrIle: 1.059 ± 0.793
1.589TyrLys: 1.589 ± 0.904
2.648TyrLeu: 2.648 ± 0.833
0.53TyrMet: 0.53 ± 0.353
0.53TyrAsn: 0.53 ± 0.778
0.53TyrPro: 0.53 ± 0.353
2.119TyrGln: 2.119 ± 0.413
0.53TyrArg: 0.53 ± 0.353
1.589TyrSer: 1.589 ± 0.521
1.059TyrThr: 1.059 ± 0.705
3.178TyrVal: 3.178 ± 0.899
0.53TyrTrp: 0.53 ± 0.396
0.53TyrTyr: 0.53 ± 0.353
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1889 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski