Amino acid dipepetide frequency for Simian adenovirus 24

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.529AlaAla: 10.529 ± 1.658
1.036AlaCys: 1.036 ± 0.448
3.28AlaAsp: 3.28 ± 0.632
4.229AlaGlu: 4.229 ± 0.707
2.675AlaPhe: 2.675 ± 0.505
4.747AlaGly: 4.747 ± 0.68
2.244AlaHis: 2.244 ± 0.486
3.366AlaIle: 3.366 ± 0.591
1.726AlaLys: 1.726 ± 0.387
8.976AlaLeu: 8.976 ± 1.148
1.295AlaMet: 1.295 ± 0.335
3.193AlaAsn: 3.193 ± 0.673
5.265AlaPro: 5.265 ± 0.82
2.158AlaGln: 2.158 ± 0.478
4.833AlaArg: 4.833 ± 0.95
6.214AlaSer: 6.214 ± 0.647
4.401AlaThr: 4.401 ± 0.552
6.3AlaVal: 6.3 ± 0.628
0.69AlaTrp: 0.69 ± 0.186
3.193AlaTyr: 3.193 ± 0.444
0.0AlaXaa: 0.0 ± 0.0
Cys
1.381CysAla: 1.381 ± 0.386
1.295CysCys: 1.295 ± 0.478
1.036CysAsp: 1.036 ± 0.28
0.863CysGlu: 0.863 ± 0.275
0.604CysPhe: 0.604 ± 0.239
1.553CysGly: 1.553 ± 0.376
0.604CysHis: 0.604 ± 0.228
1.122CysIle: 1.122 ± 0.361
0.777CysLys: 0.777 ± 0.3
1.899CysLeu: 1.899 ± 0.397
0.777CysMet: 0.777 ± 0.37
1.467CysAsn: 1.467 ± 0.464
0.863CysPro: 0.863 ± 0.283
0.345CysGln: 0.345 ± 0.15
0.777CysArg: 0.777 ± 0.261
1.122CysSer: 1.122 ± 0.334
0.863CysThr: 0.863 ± 0.284
1.122CysVal: 1.122 ± 0.359
0.432CysTrp: 0.432 ± 0.192
1.381CysTyr: 1.381 ± 0.351
0.0CysXaa: 0.0 ± 0.0
Asp
3.797AspAla: 3.797 ± 0.78
0.863AspCys: 0.863 ± 0.296
1.899AspAsp: 1.899 ± 0.413
4.401AspGlu: 4.401 ± 0.567
1.812AspPhe: 1.812 ± 0.488
3.107AspGly: 3.107 ± 0.441
0.949AspHis: 0.949 ± 0.307
1.812AspIle: 1.812 ± 0.425
1.467AspLys: 1.467 ± 0.391
5.523AspLeu: 5.523 ± 0.841
1.985AspMet: 1.985 ± 0.381
1.812AspAsn: 1.812 ± 0.523
4.315AspPro: 4.315 ± 0.546
1.122AspGln: 1.122 ± 0.247
3.452AspArg: 3.452 ± 0.83
3.28AspSer: 3.28 ± 0.623
2.071AspThr: 2.071 ± 0.558
3.107AspVal: 3.107 ± 0.448
0.949AspTrp: 0.949 ± 0.267
1.812AspTyr: 1.812 ± 0.459
0.0AspXaa: 0.0 ± 0.0
Glu
5.006GluAla: 5.006 ± 0.7
1.208GluCys: 1.208 ± 0.345
4.574GluAsp: 4.574 ± 0.722
8.285GluGlu: 8.285 ± 1.902
1.812GluPhe: 1.812 ± 0.43
3.884GluGly: 3.884 ± 0.733
1.553GluHis: 1.553 ± 0.343
2.33GluIle: 2.33 ± 0.552
2.762GluLys: 2.762 ± 0.49
6.3GluLeu: 6.3 ± 0.91
1.467GluMet: 1.467 ± 0.385
2.417GluAsn: 2.417 ± 0.564
2.589GluPro: 2.589 ± 0.53
2.762GluGln: 2.762 ± 0.522
4.143GluArg: 4.143 ± 0.706
3.452GluSer: 3.452 ± 0.776
3.797GluThr: 3.797 ± 0.48
3.797GluVal: 3.797 ± 0.564
0.604GluTrp: 0.604 ± 0.211
1.122GluTyr: 1.122 ± 0.305
0.0GluXaa: 0.0 ± 0.0
Phe
2.589PheAla: 2.589 ± 0.438
0.69PheCys: 0.69 ± 0.23
2.417PheAsp: 2.417 ± 0.499
1.726PheGlu: 1.726 ± 0.298
1.64PhePhe: 1.64 ± 0.339
1.295PheGly: 1.295 ± 0.337
0.863PheHis: 0.863 ± 0.246
1.899PheIle: 1.899 ± 0.449
1.122PheLys: 1.122 ± 0.24
3.28PheLeu: 3.28 ± 0.653
1.467PheMet: 1.467 ± 0.329
1.812PheAsn: 1.812 ± 0.311
1.726PhePro: 1.726 ± 0.319
1.985PheGln: 1.985 ± 0.318
2.244PheArg: 2.244 ± 0.378
3.193PheSer: 3.193 ± 0.402
1.899PheThr: 1.899 ± 0.394
2.417PheVal: 2.417 ± 0.368
0.086PheTrp: 0.086 ± 0.084
1.381PheTyr: 1.381 ± 0.332
0.0PheXaa: 0.0 ± 0.0
Gly
4.143GlyAla: 4.143 ± 0.574
1.295GlyCys: 1.295 ± 0.449
3.28GlyAsp: 3.28 ± 0.472
3.452GlyGlu: 3.452 ± 0.664
2.417GlyPhe: 2.417 ± 0.323
6.386GlyGly: 6.386 ± 1.084
1.553GlyHis: 1.553 ± 0.529
3.107GlyIle: 3.107 ± 0.38
1.726GlyLys: 1.726 ± 0.419
6.3GlyLeu: 6.3 ± 0.702
1.467GlyMet: 1.467 ± 0.353
2.675GlyAsn: 2.675 ± 0.634
2.589GlyPro: 2.589 ± 0.46
2.33GlyGln: 2.33 ± 0.566
5.523GlyArg: 5.523 ± 0.571
4.488GlySer: 4.488 ± 0.537
3.452GlyThr: 3.452 ± 0.625
4.747GlyVal: 4.747 ± 0.925
0.777GlyTrp: 0.777 ± 0.21
1.726GlyTyr: 1.726 ± 0.352
0.0GlyXaa: 0.0 ± 0.0
His
1.64HisAla: 1.64 ± 0.413
1.036HisCys: 1.036 ± 0.296
0.777HisAsp: 0.777 ± 0.257
1.208HisGlu: 1.208 ± 0.33
0.863HisPhe: 0.863 ± 0.29
2.244HisGly: 2.244 ± 0.422
1.122HisHis: 1.122 ± 0.325
0.604HisIle: 0.604 ± 0.24
0.604HisLys: 0.604 ± 0.229
2.158HisLeu: 2.158 ± 0.451
0.69HisMet: 0.69 ± 0.269
0.949HisAsn: 0.949 ± 0.291
2.244HisPro: 2.244 ± 0.54
0.949HisGln: 0.949 ± 0.334
2.417HisArg: 2.417 ± 0.402
1.295HisSer: 1.295 ± 0.335
1.467HisThr: 1.467 ± 0.335
1.295HisVal: 1.295 ± 0.433
0.345HisTrp: 0.345 ± 0.221
0.259HisTyr: 0.259 ± 0.124
0.0HisXaa: 0.0 ± 0.0
Ile
2.848IleAla: 2.848 ± 0.519
0.949IleCys: 0.949 ± 0.311
1.122IleAsp: 1.122 ± 0.333
1.381IleGlu: 1.381 ± 0.255
1.553IlePhe: 1.553 ± 0.354
2.071IleGly: 2.071 ± 0.439
0.777IleHis: 0.777 ± 0.271
1.812IleIle: 1.812 ± 0.408
1.899IleLys: 1.899 ± 0.376
3.193IleLeu: 3.193 ± 0.609
0.949IleMet: 0.949 ± 0.308
1.812IleAsn: 1.812 ± 0.454
2.503IlePro: 2.503 ± 0.539
1.553IleGln: 1.553 ± 0.356
2.158IleArg: 2.158 ± 0.451
3.021IleSer: 3.021 ± 0.457
3.625IleThr: 3.625 ± 0.604
3.107IleVal: 3.107 ± 0.483
0.345IleTrp: 0.345 ± 0.201
1.381IleTyr: 1.381 ± 0.358
0.0IleXaa: 0.0 ± 0.0
Lys
2.244LysAla: 2.244 ± 0.325
0.69LysCys: 0.69 ± 0.3
1.726LysAsp: 1.726 ± 0.444
2.244LysGlu: 2.244 ± 0.489
1.381LysPhe: 1.381 ± 0.417
2.503LysGly: 2.503 ± 0.586
0.949LysHis: 0.949 ± 0.398
2.158LysIle: 2.158 ± 0.41
2.244LysLys: 2.244 ± 0.521
3.193LysLeu: 3.193 ± 0.704
0.949LysMet: 0.949 ± 0.438
1.726LysAsn: 1.726 ± 0.398
2.33LysPro: 2.33 ± 0.509
1.208LysGln: 1.208 ± 0.316
2.934LysArg: 2.934 ± 0.585
2.158LysSer: 2.158 ± 0.407
1.64LysThr: 1.64 ± 0.39
1.64LysVal: 1.64 ± 0.375
0.432LysTrp: 0.432 ± 0.175
1.381LysTyr: 1.381 ± 0.32
0.0LysXaa: 0.0 ± 0.0
Leu
8.285LeuAla: 8.285 ± 0.838
1.899LeuCys: 1.899 ± 0.467
4.833LeuAsp: 4.833 ± 0.936
5.696LeuGlu: 5.696 ± 0.68
2.158LeuPhe: 2.158 ± 0.477
5.265LeuGly: 5.265 ± 0.792
2.158LeuHis: 2.158 ± 0.518
3.107LeuIle: 3.107 ± 0.712
4.315LeuLys: 4.315 ± 0.709
9.839LeuLeu: 9.839 ± 1.317
2.675LeuMet: 2.675 ± 0.463
3.711LeuAsn: 3.711 ± 0.719
7.163LeuPro: 7.163 ± 0.795
4.056LeuGln: 4.056 ± 0.501
7.94LeuArg: 7.94 ± 0.906
5.782LeuSer: 5.782 ± 0.678
6.645LeuThr: 6.645 ± 0.618
5.869LeuVal: 5.869 ± 0.844
1.64LeuTrp: 1.64 ± 0.383
3.28LeuTyr: 3.28 ± 0.671
0.0LeuXaa: 0.0 ± 0.0
Met
2.071MetAla: 2.071 ± 0.395
0.345MetCys: 0.345 ± 0.136
1.036MetAsp: 1.036 ± 0.263
1.726MetGlu: 1.726 ± 0.295
0.518MetPhe: 0.518 ± 0.223
1.295MetGly: 1.295 ± 0.26
1.122MetHis: 1.122 ± 0.424
0.949MetIle: 0.949 ± 0.293
0.863MetLys: 0.863 ± 0.268
2.417MetLeu: 2.417 ± 0.504
0.949MetMet: 0.949 ± 0.284
1.381MetAsn: 1.381 ± 0.379
1.899MetPro: 1.899 ± 0.326
1.295MetGln: 1.295 ± 0.358
1.553MetArg: 1.553 ± 0.434
2.244MetSer: 2.244 ± 0.504
1.381MetThr: 1.381 ± 0.282
1.208MetVal: 1.208 ± 0.33
0.518MetTrp: 0.518 ± 0.252
1.036MetTyr: 1.036 ± 0.198
0.0MetXaa: 0.0 ± 0.0
Asn
2.503AsnAla: 2.503 ± 0.485
0.777AsnCys: 0.777 ± 0.251
2.244AsnAsp: 2.244 ± 0.481
2.158AsnGlu: 2.158 ± 0.401
2.589AsnPhe: 2.589 ± 0.571
2.589AsnGly: 2.589 ± 0.444
0.949AsnHis: 0.949 ± 0.294
2.244AsnIle: 2.244 ± 0.516
1.208AsnLys: 1.208 ± 0.279
3.625AsnLeu: 3.625 ± 0.72
1.64AsnMet: 1.64 ± 0.564
1.985AsnAsn: 1.985 ± 0.486
2.934AsnPro: 2.934 ± 0.48
1.64AsnGln: 1.64 ± 0.386
2.071AsnArg: 2.071 ± 0.445
2.589AsnSer: 2.589 ± 0.604
2.33AsnThr: 2.33 ± 0.665
2.762AsnVal: 2.762 ± 0.576
0.777AsnTrp: 0.777 ± 0.283
2.158AsnTyr: 2.158 ± 0.584
0.0AsnXaa: 0.0 ± 0.0
Pro
6.041ProAla: 6.041 ± 0.671
0.863ProCys: 0.863 ± 0.32
3.193ProAsp: 3.193 ± 0.436
5.61ProGlu: 5.61 ± 0.66
2.503ProPhe: 2.503 ± 0.502
4.488ProGly: 4.488 ± 0.529
0.949ProHis: 0.949 ± 0.265
1.726ProIle: 1.726 ± 0.377
1.553ProLys: 1.553 ± 0.401
5.437ProLeu: 5.437 ± 0.891
1.295ProMet: 1.295 ± 0.379
2.417ProAsn: 2.417 ± 0.371
7.508ProPro: 7.508 ± 1.486
3.711ProGln: 3.711 ± 0.778
5.178ProArg: 5.178 ± 0.887
4.488ProSer: 4.488 ± 0.619
4.056ProThr: 4.056 ± 0.682
4.574ProVal: 4.574 ± 0.611
0.604ProTrp: 0.604 ± 0.2
1.726ProTyr: 1.726 ± 0.397
0.0ProXaa: 0.0 ± 0.0
Gln
3.711GlnAla: 3.711 ± 0.587
0.863GlnCys: 0.863 ± 0.272
1.899GlnAsp: 1.899 ± 0.419
3.28GlnGlu: 3.28 ± 0.571
1.295GlnPhe: 1.295 ± 0.38
2.244GlnGly: 2.244 ± 0.472
1.036GlnHis: 1.036 ± 0.3
1.122GlnIle: 1.122 ± 0.273
1.467GlnLys: 1.467 ± 0.352
3.797GlnLeu: 3.797 ± 0.577
1.122GlnMet: 1.122 ± 0.301
1.812GlnAsn: 1.812 ± 0.54
4.143GlnPro: 4.143 ± 0.608
3.452GlnGln: 3.452 ± 0.739
2.934GlnArg: 2.934 ± 0.489
2.589GlnSer: 2.589 ± 0.566
2.848GlnThr: 2.848 ± 0.523
2.503GlnVal: 2.503 ± 0.445
0.518GlnTrp: 0.518 ± 0.206
0.69GlnTyr: 0.69 ± 0.266
0.0GlnXaa: 0.0 ± 0.0
Arg
7.336ArgAla: 7.336 ± 1.369
2.071ArgCys: 2.071 ± 0.562
3.021ArgAsp: 3.021 ± 0.618
3.884ArgGlu: 3.884 ± 0.667
2.417ArgPhe: 2.417 ± 0.425
5.869ArgGly: 5.869 ± 0.648
2.158ArgHis: 2.158 ± 0.583
2.589ArgIle: 2.589 ± 0.435
2.675ArgLys: 2.675 ± 0.614
5.869ArgLeu: 5.869 ± 0.944
1.208ArgMet: 1.208 ± 0.32
3.107ArgAsn: 3.107 ± 0.546
4.919ArgPro: 4.919 ± 0.897
3.625ArgGln: 3.625 ± 0.564
8.889ArgArg: 8.889 ± 1.982
4.833ArgSer: 4.833 ± 0.796
3.452ArgThr: 3.452 ± 0.558
3.711ArgVal: 3.711 ± 0.586
1.122ArgTrp: 1.122 ± 0.235
1.208ArgTyr: 1.208 ± 0.319
0.0ArgXaa: 0.0 ± 0.0
Ser
5.265SerAla: 5.265 ± 0.668
1.036SerCys: 1.036 ± 0.287
3.538SerAsp: 3.538 ± 0.621
2.675SerGlu: 2.675 ± 0.463
2.762SerPhe: 2.762 ± 0.405
5.437SerGly: 5.437 ± 0.973
1.64SerHis: 1.64 ± 0.41
3.021SerIle: 3.021 ± 0.639
2.33SerLys: 2.33 ± 0.559
6.645SerLeu: 6.645 ± 0.758
1.553SerMet: 1.553 ± 0.407
2.503SerAsn: 2.503 ± 0.473
3.797SerPro: 3.797 ± 0.696
2.503SerGln: 2.503 ± 0.467
5.351SerArg: 5.351 ± 0.766
7.854SerSer: 7.854 ± 1.334
4.747SerThr: 4.747 ± 0.929
3.538SerVal: 3.538 ± 0.722
0.863SerTrp: 0.863 ± 0.287
2.33SerTyr: 2.33 ± 0.361
0.0SerXaa: 0.0 ± 0.0
Thr
3.452ThrAla: 3.452 ± 0.562
1.553ThrCys: 1.553 ± 0.287
2.503ThrAsp: 2.503 ± 0.661
4.056ThrGlu: 4.056 ± 0.742
2.33ThrPhe: 2.33 ± 0.529
3.711ThrGly: 3.711 ± 0.589
1.295ThrHis: 1.295 ± 0.33
1.812ThrIle: 1.812 ± 0.516
1.985ThrLys: 1.985 ± 0.61
6.473ThrLeu: 6.473 ± 0.598
0.949ThrMet: 0.949 ± 0.314
2.244ThrAsn: 2.244 ± 0.471
4.919ThrPro: 4.919 ± 0.613
2.503ThrGln: 2.503 ± 0.496
4.315ThrArg: 4.315 ± 0.573
2.934ThrSer: 2.934 ± 0.483
6.3ThrThr: 6.3 ± 1.596
5.265ThrVal: 5.265 ± 0.571
0.777ThrTrp: 0.777 ± 0.212
2.158ThrTyr: 2.158 ± 0.725
0.0ThrXaa: 0.0 ± 0.0
Val
5.092ValAla: 5.092 ± 0.642
1.036ValCys: 1.036 ± 0.367
4.056ValAsp: 4.056 ± 0.631
4.315ValGlu: 4.315 ± 0.657
2.503ValPhe: 2.503 ± 0.356
2.33ValGly: 2.33 ± 0.413
0.949ValHis: 0.949 ± 0.336
1.985ValIle: 1.985 ± 0.515
2.503ValLys: 2.503 ± 0.621
6.214ValLeu: 6.214 ± 0.851
1.985ValMet: 1.985 ± 0.405
2.589ValAsn: 2.589 ± 0.375
3.97ValPro: 3.97 ± 0.467
3.538ValGln: 3.538 ± 0.637
4.056ValArg: 4.056 ± 0.703
4.66ValSer: 4.66 ± 0.673
3.538ValThr: 3.538 ± 0.683
4.66ValVal: 4.66 ± 0.652
0.777ValTrp: 0.777 ± 0.232
2.934ValTyr: 2.934 ± 0.591
0.0ValXaa: 0.0 ± 0.0
Trp
0.432TrpAla: 0.432 ± 0.199
0.0TrpCys: 0.0 ± 0.0
0.863TrpAsp: 0.863 ± 0.275
0.777TrpGlu: 0.777 ± 0.261
0.345TrpPhe: 0.345 ± 0.162
0.863TrpGly: 0.863 ± 0.232
0.259TrpHis: 0.259 ± 0.113
0.345TrpIle: 0.345 ± 0.157
0.949TrpLys: 0.949 ± 0.321
1.208TrpLeu: 1.208 ± 0.316
0.518TrpMet: 0.518 ± 0.166
0.949TrpAsn: 0.949 ± 0.292
0.604TrpPro: 0.604 ± 0.2
0.69TrpGln: 0.69 ± 0.262
0.69TrpArg: 0.69 ± 0.304
1.208TrpSer: 1.208 ± 0.352
1.036TrpThr: 1.036 ± 0.32
0.345TrpVal: 0.345 ± 0.152
0.173TrpTrp: 0.173 ± 0.1
0.518TrpTyr: 0.518 ± 0.238
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.985TyrAla: 1.985 ± 0.442
0.777TyrCys: 0.777 ± 0.22
2.244TyrAsp: 2.244 ± 0.46
1.899TyrGlu: 1.899 ± 0.449
1.553TyrPhe: 1.553 ± 0.408
1.553TyrGly: 1.553 ± 0.422
1.036TyrHis: 1.036 ± 0.411
0.949TyrIle: 0.949 ± 0.247
1.553TyrLys: 1.553 ± 0.495
3.97TyrLeu: 3.97 ± 0.76
0.777TyrMet: 0.777 ± 0.205
1.208TyrAsn: 1.208 ± 0.347
1.64TyrPro: 1.64 ± 0.41
1.899TyrGln: 1.899 ± 0.568
2.503TyrArg: 2.503 ± 0.521
1.985TyrSer: 1.985 ± 0.484
2.071TyrThr: 2.071 ± 0.441
1.726TyrVal: 1.726 ± 0.405
0.345TyrTrp: 0.345 ± 0.146
0.69TyrTyr: 0.69 ± 0.256
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 36 proteins (11588 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski