Amino acid dipepetide frequency for Hubei picorna-like virus 62

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.823AlaAla: 4.823 ± 0.0
0.0AlaCys: 0.0 ± 0.0
3.445AlaAsp: 3.445 ± 0.0
3.1AlaGlu: 3.1 ± 0.0
2.067AlaPhe: 2.067 ± 0.0
4.823AlaGly: 4.823 ± 0.0
1.378AlaHis: 1.378 ± 0.0
4.478AlaIle: 4.478 ± 0.0
6.2AlaLys: 6.2 ± 0.0
6.545AlaLeu: 6.545 ± 0.0
2.411AlaMet: 2.411 ± 0.0
2.067AlaAsn: 2.067 ± 0.0
3.1AlaPro: 3.1 ± 0.0
2.411AlaGln: 2.411 ± 0.0
2.756AlaArg: 2.756 ± 0.0
5.167AlaSer: 5.167 ± 0.0
4.134AlaThr: 4.134 ± 0.0
4.823AlaVal: 4.823 ± 0.0
0.689AlaTrp: 0.689 ± 0.0
1.378AlaTyr: 1.378 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.033CysAsp: 1.033 ± 0.0
0.344CysGlu: 0.344 ± 0.0
0.689CysPhe: 0.689 ± 0.0
0.689CysGly: 0.689 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.689CysIle: 0.689 ± 0.0
0.689CysLys: 0.689 ± 0.0
1.378CysLeu: 1.378 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.344CysAsn: 0.344 ± 0.0
1.033CysPro: 1.033 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.689CysArg: 0.689 ± 0.0
1.378CysSer: 1.378 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.689CysVal: 0.689 ± 0.0
0.344CysTrp: 0.344 ± 0.0
0.344CysTyr: 0.344 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.789AspAla: 3.789 ± 0.0
1.378AspCys: 1.378 ± 0.0
2.756AspAsp: 2.756 ± 0.0
3.1AspGlu: 3.1 ± 0.0
2.756AspPhe: 2.756 ± 0.0
2.756AspGly: 2.756 ± 0.0
0.689AspHis: 0.689 ± 0.0
5.167AspIle: 5.167 ± 0.0
3.1AspLys: 3.1 ± 0.0
5.167AspLeu: 5.167 ± 0.0
3.1AspMet: 3.1 ± 0.0
3.445AspAsn: 3.445 ± 0.0
1.722AspPro: 1.722 ± 0.0
0.344AspGln: 0.344 ± 0.0
2.756AspArg: 2.756 ± 0.0
2.067AspSer: 2.067 ± 0.0
2.067AspThr: 2.067 ± 0.0
2.411AspVal: 2.411 ± 0.0
0.344AspTrp: 0.344 ± 0.0
2.067AspTyr: 2.067 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.789GluAla: 3.789 ± 0.0
0.344GluCys: 0.344 ± 0.0
3.445GluAsp: 3.445 ± 0.0
4.478GluGlu: 4.478 ± 0.0
1.722GluPhe: 1.722 ± 0.0
4.134GluGly: 4.134 ± 0.0
1.378GluHis: 1.378 ± 0.0
3.445GluIle: 3.445 ± 0.0
2.411GluLys: 2.411 ± 0.0
6.889GluLeu: 6.889 ± 0.0
2.756GluMet: 2.756 ± 0.0
1.378GluAsn: 1.378 ± 0.0
3.1GluPro: 3.1 ± 0.0
2.756GluGln: 2.756 ± 0.0
2.756GluArg: 2.756 ± 0.0
3.445GluSer: 3.445 ± 0.0
4.823GluThr: 4.823 ± 0.0
3.789GluVal: 3.789 ± 0.0
0.689GluTrp: 0.689 ± 0.0
4.134GluTyr: 4.134 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.134PheAla: 4.134 ± 0.0
0.689PheCys: 0.689 ± 0.0
1.722PheAsp: 1.722 ± 0.0
3.445PheGlu: 3.445 ± 0.0
1.722PhePhe: 1.722 ± 0.0
2.067PheGly: 2.067 ± 0.0
0.344PheHis: 0.344 ± 0.0
1.722PheIle: 1.722 ± 0.0
3.445PheLys: 3.445 ± 0.0
3.1PheLeu: 3.1 ± 0.0
1.033PheMet: 1.033 ± 0.0
3.445PheAsn: 3.445 ± 0.0
1.378PhePro: 1.378 ± 0.0
1.378PheGln: 1.378 ± 0.0
2.067PheArg: 2.067 ± 0.0
4.134PheSer: 4.134 ± 0.0
5.167PheThr: 5.167 ± 0.0
2.756PheVal: 2.756 ± 0.0
0.689PheTrp: 0.689 ± 0.0
1.722PheTyr: 1.722 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.756GlyAla: 2.756 ± 0.0
0.0GlyCys: 0.0 ± 0.0
1.722GlyAsp: 1.722 ± 0.0
2.756GlyGlu: 2.756 ± 0.0
2.756GlyPhe: 2.756 ± 0.0
2.756GlyGly: 2.756 ± 0.0
1.033GlyHis: 1.033 ± 0.0
3.445GlyIle: 3.445 ± 0.0
2.411GlyLys: 2.411 ± 0.0
4.478GlyLeu: 4.478 ± 0.0
2.067GlyMet: 2.067 ± 0.0
4.134GlyAsn: 4.134 ± 0.0
1.722GlyPro: 1.722 ± 0.0
0.689GlyGln: 0.689 ± 0.0
3.1GlyArg: 3.1 ± 0.0
3.445GlySer: 3.445 ± 0.0
2.411GlyThr: 2.411 ± 0.0
4.823GlyVal: 4.823 ± 0.0
0.689GlyTrp: 0.689 ± 0.0
2.756GlyTyr: 2.756 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.033HisAla: 1.033 ± 0.0
0.344HisCys: 0.344 ± 0.0
1.378HisAsp: 1.378 ± 0.0
2.067HisGlu: 2.067 ± 0.0
0.689HisPhe: 0.689 ± 0.0
1.033HisGly: 1.033 ± 0.0
0.344HisHis: 0.344 ± 0.0
1.722HisIle: 1.722 ± 0.0
1.378HisLys: 1.378 ± 0.0
2.411HisLeu: 2.411 ± 0.0
0.344HisMet: 0.344 ± 0.0
1.722HisAsn: 1.722 ± 0.0
0.344HisPro: 0.344 ± 0.0
2.411HisGln: 2.411 ± 0.0
1.033HisArg: 1.033 ± 0.0
0.689HisSer: 0.689 ± 0.0
1.378HisThr: 1.378 ± 0.0
1.378HisVal: 1.378 ± 0.0
0.344HisTrp: 0.344 ± 0.0
0.689HisTyr: 0.689 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.1IleAla: 3.1 ± 0.0
1.033IleCys: 1.033 ± 0.0
3.789IleAsp: 3.789 ± 0.0
3.445IleGlu: 3.445 ± 0.0
2.067IlePhe: 2.067 ± 0.0
3.789IleGly: 3.789 ± 0.0
2.411IleHis: 2.411 ± 0.0
4.823IleIle: 4.823 ± 0.0
4.823IleLys: 4.823 ± 0.0
5.167IleLeu: 5.167 ± 0.0
0.344IleMet: 0.344 ± 0.0
2.411IleAsn: 2.411 ± 0.0
3.1IlePro: 3.1 ± 0.0
1.378IleGln: 1.378 ± 0.0
4.478IleArg: 4.478 ± 0.0
6.545IleSer: 6.545 ± 0.0
6.2IleThr: 6.2 ± 0.0
4.478IleVal: 4.478 ± 0.0
0.689IleTrp: 0.689 ± 0.0
1.722IleTyr: 1.722 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.067LysAla: 2.067 ± 0.0
0.0LysCys: 0.0 ± 0.0
2.411LysAsp: 2.411 ± 0.0
4.478LysGlu: 4.478 ± 0.0
1.722LysPhe: 1.722 ± 0.0
2.756LysGly: 2.756 ± 0.0
2.067LysHis: 2.067 ± 0.0
4.823LysIle: 4.823 ± 0.0
4.134LysLys: 4.134 ± 0.0
4.478LysLeu: 4.478 ± 0.0
1.378LysMet: 1.378 ± 0.0
0.689LysAsn: 0.689 ± 0.0
2.411LysPro: 2.411 ± 0.0
2.411LysGln: 2.411 ± 0.0
2.756LysArg: 2.756 ± 0.0
3.445LysSer: 3.445 ± 0.0
6.2LysThr: 6.2 ± 0.0
4.134LysVal: 4.134 ± 0.0
0.689LysTrp: 0.689 ± 0.0
1.722LysTyr: 1.722 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.267LeuAla: 8.267 ± 0.0
0.344LeuCys: 0.344 ± 0.0
6.2LeuAsp: 6.2 ± 0.0
4.134LeuGlu: 4.134 ± 0.0
5.167LeuPhe: 5.167 ± 0.0
3.789LeuGly: 3.789 ± 0.0
3.1LeuHis: 3.1 ± 0.0
2.411LeuIle: 2.411 ± 0.0
4.478LeuLys: 4.478 ± 0.0
6.2LeuLeu: 6.2 ± 0.0
3.1LeuMet: 3.1 ± 0.0
3.445LeuAsn: 3.445 ± 0.0
5.512LeuPro: 5.512 ± 0.0
3.445LeuGln: 3.445 ± 0.0
5.856LeuArg: 5.856 ± 0.0
6.2LeuSer: 6.2 ± 0.0
6.889LeuThr: 6.889 ± 0.0
3.789LeuVal: 3.789 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
2.067LeuTyr: 2.067 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.067MetAla: 2.067 ± 0.0
0.689MetCys: 0.689 ± 0.0
0.689MetAsp: 0.689 ± 0.0
1.033MetGlu: 1.033 ± 0.0
2.411MetPhe: 2.411 ± 0.0
1.033MetGly: 1.033 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.033MetIle: 1.033 ± 0.0
2.067MetLys: 2.067 ± 0.0
1.378MetLeu: 1.378 ± 0.0
0.344MetMet: 0.344 ± 0.0
2.756MetAsn: 2.756 ± 0.0
3.1MetPro: 3.1 ± 0.0
1.722MetGln: 1.722 ± 0.0
1.033MetArg: 1.033 ± 0.0
1.378MetSer: 1.378 ± 0.0
2.756MetThr: 2.756 ± 0.0
0.689MetVal: 0.689 ± 0.0
0.344MetTrp: 0.344 ± 0.0
0.689MetTyr: 0.689 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.445AsnAla: 3.445 ± 0.0
0.344AsnCys: 0.344 ± 0.0
1.722AsnAsp: 1.722 ± 0.0
2.411AsnGlu: 2.411 ± 0.0
3.789AsnPhe: 3.789 ± 0.0
2.067AsnGly: 2.067 ± 0.0
1.033AsnHis: 1.033 ± 0.0
1.722AsnIle: 1.722 ± 0.0
3.789AsnLys: 3.789 ± 0.0
6.2AsnLeu: 6.2 ± 0.0
2.411AsnMet: 2.411 ± 0.0
3.1AsnAsn: 3.1 ± 0.0
6.545AsnPro: 6.545 ± 0.0
3.1AsnGln: 3.1 ± 0.0
2.756AsnArg: 2.756 ± 0.0
2.411AsnSer: 2.411 ± 0.0
2.067AsnThr: 2.067 ± 0.0
3.445AsnVal: 3.445 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
2.756AsnTyr: 2.756 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.445ProAla: 3.445 ± 0.0
0.344ProCys: 0.344 ± 0.0
2.411ProAsp: 2.411 ± 0.0
4.134ProGlu: 4.134 ± 0.0
2.067ProPhe: 2.067 ± 0.0
3.445ProGly: 3.445 ± 0.0
1.378ProHis: 1.378 ± 0.0
4.134ProIle: 4.134 ± 0.0
1.722ProLys: 1.722 ± 0.0
2.756ProLeu: 2.756 ± 0.0
0.344ProMet: 0.344 ± 0.0
2.411ProAsn: 2.411 ± 0.0
3.1ProPro: 3.1 ± 0.0
3.1ProGln: 3.1 ± 0.0
1.033ProArg: 1.033 ± 0.0
4.823ProSer: 4.823 ± 0.0
5.512ProThr: 5.512 ± 0.0
3.445ProVal: 3.445 ± 0.0
0.689ProTrp: 0.689 ± 0.0
3.1ProTyr: 3.1 ± 0.0
0.344ProXaa: 0.344 ± 0.0
Gln
1.722GlnAla: 1.722 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.411GlnAsp: 2.411 ± 0.0
3.789GlnGlu: 3.789 ± 0.0
3.1GlnPhe: 3.1 ± 0.0
2.756GlnGly: 2.756 ± 0.0
1.033GlnHis: 1.033 ± 0.0
1.722GlnIle: 1.722 ± 0.0
1.033GlnLys: 1.033 ± 0.0
3.1GlnLeu: 3.1 ± 0.0
0.689GlnMet: 0.689 ± 0.0
2.411GlnAsn: 2.411 ± 0.0
3.1GlnPro: 3.1 ± 0.0
2.067GlnGln: 2.067 ± 0.0
1.033GlnArg: 1.033 ± 0.0
1.722GlnSer: 1.722 ± 0.0
2.067GlnThr: 2.067 ± 0.0
1.378GlnVal: 1.378 ± 0.0
0.689GlnTrp: 0.689 ± 0.0
1.722GlnTyr: 1.722 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.1ArgAla: 3.1 ± 0.0
0.689ArgCys: 0.689 ± 0.0
3.789ArgAsp: 3.789 ± 0.0
4.478ArgGlu: 4.478 ± 0.0
3.445ArgPhe: 3.445 ± 0.0
1.033ArgGly: 1.033 ± 0.0
0.689ArgHis: 0.689 ± 0.0
3.1ArgIle: 3.1 ± 0.0
1.722ArgLys: 1.722 ± 0.0
4.823ArgLeu: 4.823 ± 0.0
0.689ArgMet: 0.689 ± 0.0
2.756ArgAsn: 2.756 ± 0.0
2.067ArgPro: 2.067 ± 0.0
2.067ArgGln: 2.067 ± 0.0
0.689ArgArg: 0.689 ± 0.0
2.067ArgSer: 2.067 ± 0.0
1.722ArgThr: 1.722 ± 0.0
5.167ArgVal: 5.167 ± 0.0
0.344ArgTrp: 0.344 ± 0.0
3.445ArgTyr: 3.445 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
8.267SerAla: 8.267 ± 0.0
1.033SerCys: 1.033 ± 0.0
2.411SerAsp: 2.411 ± 0.0
3.445SerGlu: 3.445 ± 0.0
4.478SerPhe: 4.478 ± 0.0
2.411SerGly: 2.411 ± 0.0
1.378SerHis: 1.378 ± 0.0
4.823SerIle: 4.823 ± 0.0
2.756SerLys: 2.756 ± 0.0
5.512SerLeu: 5.512 ± 0.0
2.067SerMet: 2.067 ± 0.0
5.167SerAsn: 5.167 ± 0.0
4.478SerPro: 4.478 ± 0.0
3.1SerGln: 3.1 ± 0.0
2.756SerArg: 2.756 ± 0.0
3.789SerSer: 3.789 ± 0.0
5.167SerThr: 5.167 ± 0.0
5.512SerVal: 5.512 ± 0.0
1.722SerTrp: 1.722 ± 0.0
2.756SerTyr: 2.756 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.1ThrAla: 3.1 ± 0.0
1.722ThrCys: 1.722 ± 0.0
4.478ThrAsp: 4.478 ± 0.0
2.067ThrGlu: 2.067 ± 0.0
2.756ThrPhe: 2.756 ± 0.0
3.789ThrGly: 3.789 ± 0.0
2.411ThrHis: 2.411 ± 0.0
6.2ThrIle: 6.2 ± 0.0
3.1ThrLys: 3.1 ± 0.0
6.889ThrLeu: 6.889 ± 0.0
2.411ThrMet: 2.411 ± 0.0
6.545ThrAsn: 6.545 ± 0.0
3.789ThrPro: 3.789 ± 0.0
2.067ThrGln: 2.067 ± 0.0
3.1ThrArg: 3.1 ± 0.0
8.267ThrSer: 8.267 ± 0.0
7.234ThrThr: 7.234 ± 0.0
4.478ThrVal: 4.478 ± 0.0
0.344ThrTrp: 0.344 ± 0.0
2.411ThrTyr: 2.411 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.789ValAla: 3.789 ± 0.0
0.689ValCys: 0.689 ± 0.0
2.756ValAsp: 2.756 ± 0.0
6.2ValGlu: 6.2 ± 0.0
1.378ValPhe: 1.378 ± 0.0
3.789ValGly: 3.789 ± 0.0
0.344ValHis: 0.344 ± 0.0
4.134ValIle: 4.134 ± 0.0
4.134ValLys: 4.134 ± 0.0
3.445ValLeu: 3.445 ± 0.0
0.344ValMet: 0.344 ± 0.0
3.445ValAsn: 3.445 ± 0.0
3.1ValPro: 3.1 ± 0.0
1.378ValGln: 1.378 ± 0.0
4.478ValArg: 4.478 ± 0.0
6.2ValSer: 6.2 ± 0.0
7.234ValThr: 7.234 ± 0.0
5.167ValVal: 5.167 ± 0.0
0.344ValTrp: 0.344 ± 0.0
2.411ValTyr: 2.411 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.344TrpAla: 0.344 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.689TrpAsp: 0.689 ± 0.0
0.689TrpGlu: 0.689 ± 0.0
0.344TrpPhe: 0.344 ± 0.0
0.344TrpGly: 0.344 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.378TrpIle: 1.378 ± 0.0
0.689TrpLys: 0.689 ± 0.0
0.689TrpLeu: 0.689 ± 0.0
1.033TrpMet: 1.033 ± 0.0
0.689TrpAsn: 0.689 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.344TrpGln: 0.344 ± 0.0
0.344TrpArg: 0.344 ± 0.0
1.378TrpSer: 1.378 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.344TrpVal: 0.344 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.689TrpTyr: 0.689 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.1TyrAla: 3.1 ± 0.0
0.689TyrCys: 0.689 ± 0.0
1.378TyrAsp: 1.378 ± 0.0
2.067TyrGlu: 2.067 ± 0.0
1.033TyrPhe: 1.033 ± 0.0
0.689TyrGly: 0.689 ± 0.0
1.722TyrHis: 1.722 ± 0.0
4.823TyrIle: 4.823 ± 0.0
0.689TyrLys: 0.689 ± 0.0
3.789TyrLeu: 3.789 ± 0.0
0.0TyrMet: 0.0 ± 0.0
2.756TyrAsn: 2.756 ± 0.0
1.033TyrPro: 1.033 ± 0.0
1.378TyrGln: 1.378 ± 0.0
2.411TyrArg: 2.411 ± 0.0
4.478TyrSer: 4.478 ± 0.0
4.134TyrThr: 4.134 ± 0.0
2.067TyrVal: 2.067 ± 0.0
0.344TyrTrp: 0.344 ± 0.0
2.067TyrTyr: 2.067 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.344XaaAsp: 0.344 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2904 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski