Amino acid dipepetide frequency for Wild vitis virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.623AlaAla: 3.623 ± 1.414
2.717AlaCys: 2.717 ± 1.572
2.717AlaAsp: 2.717 ± 1.664
1.812AlaGlu: 1.812 ± 1.048
0.906AlaPhe: 0.906 ± 0.816
1.812AlaGly: 1.812 ± 1.04
0.0AlaHis: 0.0 ± 0.0
2.717AlaIle: 2.717 ± 1.651
0.906AlaLys: 0.906 ± 0.816
4.529AlaLeu: 4.529 ± 1.267
1.812AlaMet: 1.812 ± 1.079
2.717AlaAsn: 2.717 ± 1.55
0.906AlaPro: 0.906 ± 0.739
4.529AlaGln: 4.529 ± 2.369
6.341AlaArg: 6.341 ± 1.59
3.623AlaSer: 3.623 ± 1.282
1.812AlaThr: 1.812 ± 1.689
0.906AlaVal: 0.906 ± 0.816
0.0AlaTrp: 0.0 ± 0.0
0.906AlaTyr: 0.906 ± 0.816
0.0AlaXaa: 0.0 ± 0.0
Cys
0.906CysAla: 0.906 ± 0.739
0.906CysCys: 0.906 ± 0.816
2.717CysAsp: 2.717 ± 1.052
2.717CysGlu: 2.717 ± 1.716
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.906CysHis: 0.906 ± 0.819
0.0CysIle: 0.0 ± 0.0
1.812CysLys: 1.812 ± 1.057
2.717CysLeu: 2.717 ± 1.052
0.0CysMet: 0.0 ± 0.0
2.717CysAsn: 2.717 ± 1.334
1.812CysPro: 1.812 ± 1.027
0.906CysGln: 0.906 ± 0.739
0.906CysArg: 0.906 ± 0.844
2.717CysSer: 2.717 ± 1.767
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.529AspAla: 4.529 ± 0.978
0.0AspCys: 0.0 ± 0.0
5.435AspAsp: 5.435 ± 1.696
1.812AspGlu: 1.812 ± 1.082
2.717AspPhe: 2.717 ± 1.651
4.529AspGly: 4.529 ± 1.261
0.906AspHis: 0.906 ± 0.844
4.529AspIle: 4.529 ± 1.731
2.717AspLys: 2.717 ± 1.664
3.623AspLeu: 3.623 ± 1.808
0.906AspMet: 0.906 ± 0.794
0.906AspAsn: 0.906 ± 0.844
2.717AspPro: 2.717 ± 1.169
1.812AspGln: 1.812 ± 1.081
4.529AspArg: 4.529 ± 1.168
2.717AspSer: 2.717 ± 1.688
3.623AspThr: 3.623 ± 1.35
7.246AspVal: 7.246 ± 2.679
0.0AspTrp: 0.0 ± 0.0
1.812AspTyr: 1.812 ± 1.082
0.0AspXaa: 0.0 ± 0.0
Glu
2.717GluAla: 2.717 ± 1.064
0.0GluCys: 0.0 ± 0.0
3.623GluAsp: 3.623 ± 1.771
3.623GluGlu: 3.623 ± 1.569
1.812GluPhe: 1.812 ± 1.689
3.623GluGly: 3.623 ± 1.013
2.717GluHis: 2.717 ± 1.664
4.529GluIle: 4.529 ± 2.149
2.717GluLys: 2.717 ± 1.679
7.246GluLeu: 7.246 ± 2.309
0.906GluMet: 0.906 ± 0.906
3.623GluAsn: 3.623 ± 1.549
1.812GluPro: 1.812 ± 0.981
0.906GluGln: 0.906 ± 0.79
5.435GluArg: 5.435 ± 1.345
5.435GluSer: 5.435 ± 2.295
4.529GluThr: 4.529 ± 1.35
2.717GluVal: 2.717 ± 1.758
0.906GluTrp: 0.906 ± 0.816
3.623GluTyr: 3.623 ± 2.433
0.0GluXaa: 0.0 ± 0.0
Phe
2.717PheAla: 2.717 ± 0.834
0.0PheCys: 0.0 ± 0.0
1.812PheAsp: 1.812 ± 1.027
0.906PheGlu: 0.906 ± 0.816
5.435PhePhe: 5.435 ± 2.209
0.906PheGly: 0.906 ± 0.844
1.812PheHis: 1.812 ± 0.919
0.906PheIle: 0.906 ± 0.79
1.812PheLys: 1.812 ± 0.85
3.623PheLeu: 3.623 ± 2.313
2.717PheMet: 2.717 ± 0.993
5.435PheAsn: 5.435 ± 1.96
1.812PhePro: 1.812 ± 1.177
1.812PheGln: 1.812 ± 1.048
3.623PheArg: 3.623 ± 1.39
3.623PheSer: 3.623 ± 1.39
0.906PheThr: 0.906 ± 0.739
2.717PheVal: 2.717 ± 1.005
0.906PheTrp: 0.906 ± 0.739
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.623GlyAla: 3.623 ± 1.309
0.906GlyCys: 0.906 ± 0.816
3.623GlyAsp: 3.623 ± 0.875
4.529GlyGlu: 4.529 ± 2.643
0.0GlyPhe: 0.0 ± 0.0
5.435GlyGly: 5.435 ± 1.459
1.812GlyHis: 1.812 ± 0.85
4.529GlyIle: 4.529 ± 2.338
2.717GlyLys: 2.717 ± 1.651
4.529GlyLeu: 4.529 ± 1.344
0.906GlyMet: 0.906 ± 0.906
1.812GlyAsn: 1.812 ± 1.479
3.623GlyPro: 3.623 ± 1.526
0.0GlyGln: 0.0 ± 0.0
0.906GlyArg: 0.906 ± 0.739
9.964GlySer: 9.964 ± 2.854
0.906GlyThr: 0.906 ± 0.844
1.812GlyVal: 1.812 ± 1.479
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.812HisAla: 1.812 ± 1.689
0.906HisCys: 0.906 ± 0.844
1.812HisAsp: 1.812 ± 1.177
0.906HisGlu: 0.906 ± 0.844
0.906HisPhe: 0.906 ± 0.844
1.812HisGly: 1.812 ± 1.02
0.906HisHis: 0.906 ± 0.816
0.0HisIle: 0.0 ± 0.0
0.906HisLys: 0.906 ± 0.906
2.717HisLeu: 2.717 ± 2.533
0.906HisMet: 0.906 ± 0.844
1.812HisAsn: 1.812 ± 1.057
1.812HisPro: 1.812 ± 1.04
1.812HisGln: 1.812 ± 0.942
2.717HisArg: 2.717 ± 1.664
2.717HisSer: 2.717 ± 1.106
1.812HisThr: 1.812 ± 1.02
0.906HisVal: 0.906 ± 0.79
0.906HisTrp: 0.906 ± 0.844
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.717IleAla: 2.717 ± 0.834
0.0IleCys: 0.0 ± 0.0
3.623IleAsp: 3.623 ± 1.604
5.435IleGlu: 5.435 ± 1.556
2.717IlePhe: 2.717 ± 1.351
2.717IleGly: 2.717 ± 1.005
0.906IleHis: 0.906 ± 0.844
5.435IleIle: 5.435 ± 1.629
3.623IleLys: 3.623 ± 1.509
2.717IleLeu: 2.717 ± 1.633
1.812IleMet: 1.812 ± 1.812
1.812IleAsn: 1.812 ± 1.048
5.435IlePro: 5.435 ± 2.112
2.717IleGln: 2.717 ± 2.457
2.717IleArg: 2.717 ± 1.694
4.529IleSer: 4.529 ± 1.81
4.529IleThr: 4.529 ± 1.839
2.717IleVal: 2.717 ± 1.733
0.906IleTrp: 0.906 ± 0.906
1.812IleTyr: 1.812 ± 1.204
0.0IleXaa: 0.0 ± 0.0
Lys
1.812LysAla: 1.812 ± 1.057
0.906LysCys: 0.906 ± 0.816
3.623LysAsp: 3.623 ± 1.604
2.717LysGlu: 2.717 ± 1.694
0.906LysPhe: 0.906 ± 0.844
2.717LysGly: 2.717 ± 1.106
4.529LysHis: 4.529 ± 1.415
2.717LysIle: 2.717 ± 1.061
3.623LysLys: 3.623 ± 2.44
2.717LysLeu: 2.717 ± 1.355
0.0LysMet: 0.0 ± 0.0
1.812LysAsn: 1.812 ± 1.177
2.717LysPro: 2.717 ± 1.524
0.906LysGln: 0.906 ± 0.739
4.529LysArg: 4.529 ± 3.111
2.717LysSer: 2.717 ± 1.694
5.435LysThr: 5.435 ± 2.35
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
0.906LysTyr: 0.906 ± 0.79
0.0LysXaa: 0.0 ± 0.0
Leu
1.812LeuAla: 1.812 ± 0.85
0.906LeuCys: 0.906 ± 0.79
7.246LeuAsp: 7.246 ± 1.713
6.341LeuGlu: 6.341 ± 2.831
1.812LeuPhe: 1.812 ± 1.048
4.529LeuGly: 4.529 ± 2.222
2.717LeuHis: 2.717 ± 1.053
5.435LeuIle: 5.435 ± 3.109
5.435LeuLys: 5.435 ± 1.686
8.152LeuLeu: 8.152 ± 2.947
0.0LeuMet: 0.0 ± 0.0
1.812LeuAsn: 1.812 ± 1.638
4.529LeuPro: 4.529 ± 1.684
3.623LeuGln: 3.623 ± 1.543
4.529LeuArg: 4.529 ± 1.261
4.529LeuSer: 4.529 ± 2.369
7.246LeuThr: 7.246 ± 2.188
3.623LeuVal: 3.623 ± 1.196
0.906LeuTrp: 0.906 ± 0.816
2.717LeuTyr: 2.717 ± 1.351
0.0LeuXaa: 0.0 ± 0.0
Met
0.906MetAla: 0.906 ± 0.819
0.906MetCys: 0.906 ± 0.816
0.0MetAsp: 0.0 ± 0.0
1.812MetGlu: 1.812 ± 1.204
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.812MetLeu: 1.812 ± 1.081
0.906MetMet: 0.906 ± 1.04
0.906MetAsn: 0.906 ± 0.79
1.812MetPro: 1.812 ± 0.942
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.812MetSer: 1.812 ± 1.082
1.812MetThr: 1.812 ± 1.04
3.623MetVal: 3.623 ± 1.493
0.906MetTrp: 0.906 ± 0.79
1.812MetTyr: 1.812 ± 1.048
0.0MetXaa: 0.0 ± 0.0
Asn
0.906AsnAla: 0.906 ± 0.816
1.812AsnCys: 1.812 ± 1.027
3.623AsnAsp: 3.623 ± 1.69
3.623AsnGlu: 3.623 ± 1.013
1.812AsnPhe: 1.812 ± 1.048
3.623AsnGly: 3.623 ± 2.407
0.906AsnHis: 0.906 ± 0.844
2.717AsnIle: 2.717 ± 1.083
0.906AsnLys: 0.906 ± 0.739
1.812AsnLeu: 1.812 ± 0.981
0.906AsnMet: 0.906 ± 0.819
2.717AsnAsn: 2.717 ± 1.569
4.529AsnPro: 4.529 ± 2.542
0.906AsnGln: 0.906 ± 0.844
5.435AsnArg: 5.435 ± 2.125
8.152AsnSer: 8.152 ± 2.617
4.529AsnThr: 4.529 ± 3.076
1.812AsnVal: 1.812 ± 1.581
0.906AsnTrp: 0.906 ± 0.79
3.623AsnTyr: 3.623 ± 1.577
0.0AsnXaa: 0.0 ± 0.0
Pro
5.435ProAla: 5.435 ± 3.33
2.717ProCys: 2.717 ± 1.21
1.812ProAsp: 1.812 ± 1.134
2.717ProGlu: 2.717 ± 1.55
1.812ProPhe: 1.812 ± 1.048
0.906ProGly: 0.906 ± 0.816
2.717ProHis: 2.717 ± 0.949
2.717ProIle: 2.717 ± 1.355
1.812ProLys: 1.812 ± 1.082
2.717ProLeu: 2.717 ± 1.338
0.0ProMet: 0.0 ± 0.0
3.623ProAsn: 3.623 ± 1.551
3.623ProPro: 3.623 ± 1.884
3.623ProGln: 3.623 ± 1.7
3.623ProArg: 3.623 ± 1.493
5.435ProSer: 5.435 ± 1.775
6.341ProThr: 6.341 ± 2.144
2.717ProVal: 2.717 ± 0.834
0.906ProTrp: 0.906 ± 0.79
2.717ProTyr: 2.717 ± 1.061
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.812GlnCys: 1.812 ± 1.027
0.906GlnAsp: 0.906 ± 0.819
1.812GlnGlu: 1.812 ± 0.85
1.812GlnPhe: 1.812 ± 0.85
0.906GlnGly: 0.906 ± 0.739
0.906GlnHis: 0.906 ± 0.79
1.812GlnIle: 1.812 ± 1.027
0.906GlnLys: 0.906 ± 0.819
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
6.341GlnAsn: 6.341 ± 3.212
2.717GlnPro: 2.717 ± 1.696
0.906GlnGln: 0.906 ± 0.819
2.717GlnArg: 2.717 ± 0.949
1.812GlnSer: 1.812 ± 1.057
1.812GlnThr: 1.812 ± 1.027
0.906GlnVal: 0.906 ± 0.79
0.0GlnTrp: 0.0 ± 0.0
2.717GlnTyr: 2.717 ± 1.651
0.0GlnXaa: 0.0 ± 0.0
Arg
2.717ArgAla: 2.717 ± 2.218
3.623ArgCys: 3.623 ± 2.597
1.812ArgAsp: 1.812 ± 1.04
2.717ArgGlu: 2.717 ± 1.664
4.529ArgPhe: 4.529 ± 1.07
1.812ArgGly: 1.812 ± 1.632
0.906ArgHis: 0.906 ± 0.844
1.812ArgIle: 1.812 ± 0.85
4.529ArgLys: 4.529 ± 1.475
8.152ArgLeu: 8.152 ± 1.566
0.906ArgMet: 0.906 ± 0.819
7.246ArgAsn: 7.246 ± 2.05
4.529ArgPro: 4.529 ± 2.388
1.812ArgGln: 1.812 ± 0.942
19.022ArgArg: 19.022 ± 6.721
7.246ArgSer: 7.246 ± 2.514
2.717ArgThr: 2.717 ± 0.949
5.435ArgVal: 5.435 ± 2.369
0.0ArgTrp: 0.0 ± 0.0
1.812ArgTyr: 1.812 ± 0.919
0.0ArgXaa: 0.0 ± 0.0
Ser
1.812SerAla: 1.812 ± 1.027
0.906SerCys: 0.906 ± 0.816
4.529SerAsp: 4.529 ± 1.473
8.152SerGlu: 8.152 ± 2.454
7.246SerPhe: 7.246 ± 1.738
6.341SerGly: 6.341 ± 1.227
0.906SerHis: 0.906 ± 0.819
5.435SerIle: 5.435 ± 2.741
6.341SerLys: 6.341 ± 2.815
5.435SerLeu: 5.435 ± 2.112
3.623SerMet: 3.623 ± 1.568
3.623SerAsn: 3.623 ± 1.623
2.717SerPro: 2.717 ± 1.772
3.623SerGln: 3.623 ± 1.623
8.152SerArg: 8.152 ± 2.852
14.493SerSer: 14.493 ± 7.053
6.341SerThr: 6.341 ± 3.287
4.529SerVal: 4.529 ± 2.153
0.0SerTrp: 0.0 ± 0.0
5.435SerTyr: 5.435 ± 1.195
0.0SerXaa: 0.0 ± 0.0
Thr
0.906ThrAla: 0.906 ± 0.844
0.906ThrCys: 0.906 ± 0.819
3.623ThrAsp: 3.623 ± 1.821
4.529ThrGlu: 4.529 ± 1.839
3.623ThrPhe: 3.623 ± 1.503
5.435ThrGly: 5.435 ± 2.697
0.0ThrHis: 0.0 ± 0.0
4.529ThrIle: 4.529 ± 1.508
1.812ThrLys: 1.812 ± 1.689
7.246ThrLeu: 7.246 ± 2.734
1.812ThrMet: 1.812 ± 1.581
0.0ThrAsn: 0.0 ± 0.0
4.529ThrPro: 4.529 ± 2.177
0.0ThrGln: 0.0 ± 0.0
0.906ThrArg: 0.906 ± 0.739
10.87ThrSer: 10.87 ± 4.336
2.717ThrThr: 2.717 ± 1.55
3.623ThrVal: 3.623 ± 1.7
1.812ThrTrp: 1.812 ± 0.942
2.717ThrTyr: 2.717 ± 1.55
0.0ThrXaa: 0.0 ± 0.0
Val
1.812ValAla: 1.812 ± 0.85
0.0ValCys: 0.0 ± 0.0
3.623ValAsp: 3.623 ± 1.739
4.529ValGlu: 4.529 ± 1.619
3.623ValPhe: 3.623 ± 1.26
1.812ValGly: 1.812 ± 0.85
2.717ValHis: 2.717 ± 1.664
5.435ValIle: 5.435 ± 1.448
2.717ValLys: 2.717 ± 1.302
3.623ValLeu: 3.623 ± 2.117
0.0ValMet: 0.0 ± 0.0
1.812ValAsn: 1.812 ± 1.177
2.717ValPro: 2.717 ± 1.302
0.0ValGln: 0.0 ± 0.0
3.623ValArg: 3.623 ± 1.405
5.435ValSer: 5.435 ± 1.459
3.623ValThr: 3.623 ± 1.557
3.623ValVal: 3.623 ± 2.117
0.0ValTrp: 0.0 ± 0.0
2.717ValTyr: 2.717 ± 1.053
0.0ValXaa: 0.0 ± 0.0
Trp
2.717TrpAla: 2.717 ± 1.679
0.906TrpCys: 0.906 ± 0.79
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.906TrpPhe: 0.906 ± 0.816
0.0TrpGly: 0.0 ± 0.0
0.906TrpHis: 0.906 ± 0.79
1.812TrpIle: 1.812 ± 0.85
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.906TrpPro: 0.906 ± 0.844
0.0TrpGln: 0.0 ± 0.0
0.906TrpArg: 0.906 ± 0.906
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.906TrpTyr: 0.906 ± 0.819
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.812TyrAla: 1.812 ± 1.689
0.906TyrCys: 0.906 ± 0.739
0.906TyrAsp: 0.906 ± 0.816
1.812TyrGlu: 1.812 ± 1.134
0.906TyrPhe: 0.906 ± 0.739
2.717TyrGly: 2.717 ± 1.169
0.906TyrHis: 0.906 ± 0.844
1.812TyrIle: 1.812 ± 1.04
0.0TyrLys: 0.0 ± 0.0
4.529TyrLeu: 4.529 ± 1.168
0.906TyrMet: 0.906 ± 0.844
4.529TyrAsn: 4.529 ± 1.508
2.717TyrPro: 2.717 ± 1.524
0.906TyrGln: 0.906 ± 0.844
2.717TyrArg: 2.717 ± 1.005
1.812TyrSer: 1.812 ± 1.632
0.906TyrThr: 0.906 ± 0.819
4.529TyrVal: 4.529 ± 2.149
0.906TyrTrp: 0.906 ± 0.79
0.906TyrTyr: 0.906 ± 0.79
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1105 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski