Amino acid dipepetide frequency for Colletotrichum shisoi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.665AlaAla: 11.665 ± 0.085	1.107AlaCys: 1.107 ± 0.016	4.918AlaAsp: 4.918 ± 0.034	5.585AlaGlu: 5.585 ± 0.044	3.261AlaPhe: 3.261 ± 0.028	6.652AlaGly: 6.652 ± 0.041	1.848AlaHis: 1.848 ± 0.019	4.068AlaIle: 4.068 ± 0.03	4.169AlaLys: 4.169 ± 0.035	8.006AlaLeu: 8.006 ± 0.047	2.074AlaMet: 2.074 ± 0.022	3.087AlaAsn: 3.087 ± 0.026	5.508AlaPro: 5.508 ± 0.05	3.476AlaGln: 3.476 ± 0.032	5.509AlaArg: 5.509 ± 0.043	7.767AlaSer: 7.767 ± 0.053	5.661AlaThr: 5.661 ± 0.047	6.347AlaVal: 6.347 ± 0.041	1.302AlaTrp: 1.302 ± 0.017	2.209AlaTyr: 2.209 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.954CysAla: 0.954 ± 0.014	0.232CysCys: 0.232 ± 0.007	0.646CysAsp: 0.646 ± 0.011	0.562CysGlu: 0.562 ± 0.01	0.519CysPhe: 0.519 ± 0.01	0.969CysGly: 0.969 ± 0.017	0.314CysHis: 0.314 ± 0.007	0.613CysIle: 0.613 ± 0.011	0.479CysLys: 0.479 ± 0.011	1.163CysLeu: 1.163 ± 0.016	0.258CysMet: 0.258 ± 0.007	0.417CysAsn: 0.417 ± 0.011	0.661CysPro: 0.661 ± 0.012	0.415CysGln: 0.415 ± 0.01	0.778CysArg: 0.778 ± 0.014	0.856CysSer: 0.856 ± 0.015	0.63CysThr: 0.63 ± 0.012	0.795CysVal: 0.795 ± 0.014	0.213CysTrp: 0.213 ± 0.007	0.325CysTyr: 0.325 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.42AspAla: 5.42 ± 0.038	0.618AspCys: 0.618 ± 0.013	5.015AspAsp: 5.015 ± 0.052	4.578AspGlu: 4.578 ± 0.043	2.279AspPhe: 2.279 ± 0.021	4.622AspGly: 4.622 ± 0.037	1.232AspHis: 1.232 ± 0.016	2.75AspIle: 2.75 ± 0.024	2.444AspLys: 2.444 ± 0.026	4.98AspLeu: 4.98 ± 0.033	1.297AspMet: 1.297 ± 0.016	1.849AspAsn: 1.849 ± 0.017	3.389AspPro: 3.389 ± 0.025	1.761AspGln: 1.761 ± 0.018	3.175AspArg: 3.175 ± 0.029	3.842AspSer: 3.842 ± 0.031	2.841AspThr: 2.841 ± 0.023	4.033AspVal: 4.033 ± 0.034	0.9AspTrp: 0.9 ± 0.014	1.531AspTyr: 1.531 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.788GluAla: 5.788 ± 0.048	0.578GluCys: 0.578 ± 0.011	4.219GluAsp: 4.219 ± 0.036	5.246GluGlu: 5.246 ± 0.057	1.85GluPhe: 1.85 ± 0.019	3.811GluGly: 3.811 ± 0.031	1.348GluHis: 1.348 ± 0.017	2.67GluIle: 2.67 ± 0.023	3.498GluLys: 3.498 ± 0.033	4.901GluLeu: 4.901 ± 0.039	1.46GluMet: 1.46 ± 0.018	2.092GluAsn: 2.092 ± 0.022	2.943GluPro: 2.943 ± 0.041	2.273GluGln: 2.273 ± 0.025	3.904GluArg: 3.904 ± 0.038	4.026GluSer: 4.026 ± 0.035	3.503GluThr: 3.503 ± 0.03	3.601GluVal: 3.601 ± 0.03	0.875GluTrp: 0.875 ± 0.013	1.527GluTyr: 1.527 ± 0.019	0.001GluXaa: 0.001 ± 0.0
Phe	3.24PheAla: 3.24 ± 0.027	0.549PheCys: 0.549 ± 0.01	2.314PheAsp: 2.314 ± 0.024	2.056PheGlu: 2.056 ± 0.021	1.616PhePhe: 1.616 ± 0.019	2.946PheGly: 2.946 ± 0.03	0.874PheHis: 0.874 ± 0.012	1.615PheIle: 1.615 ± 0.021	1.442PheLys: 1.442 ± 0.018	3.339PheLeu: 3.339 ± 0.028	0.773PheMet: 0.773 ± 0.013	1.39PheAsn: 1.39 ± 0.015	1.91PhePro: 1.91 ± 0.022	1.314PheGln: 1.314 ± 0.016	2.006PheArg: 2.006 ± 0.019	2.853PheSer: 2.853 ± 0.026	2.071PheThr: 2.071 ± 0.024	2.543PheVal: 2.543 ± 0.027	0.643PheTrp: 0.643 ± 0.012	1.075PheTyr: 1.075 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	6.08GlyAla: 6.08 ± 0.041	0.883GlyCys: 0.883 ± 0.015	4.015GlyAsp: 4.015 ± 0.029	3.727GlyGlu: 3.727 ± 0.026	2.916GlyPhe: 2.916 ± 0.026	7.004GlyGly: 7.004 ± 0.06	1.774GlyHis: 1.774 ± 0.02	3.395GlyIle: 3.395 ± 0.031	3.367GlyLys: 3.367 ± 0.029	6.287GlyLeu: 6.287 ± 0.045	1.632GlyMet: 1.632 ± 0.022	2.624GlyAsn: 2.624 ± 0.028	3.72GlyPro: 3.72 ± 0.036	2.581GlyGln: 2.581 ± 0.024	4.546GlyArg: 4.546 ± 0.035	5.925GlySer: 5.925 ± 0.048	4.189GlyThr: 4.189 ± 0.05	4.7GlyVal: 4.7 ± 0.038	1.2GlyTrp: 1.2 ± 0.015	2.102GlyTyr: 2.102 ± 0.022	0.001GlyXaa: 0.001 ± 0.0
His	1.921HisAla: 1.921 ± 0.019	0.329HisCys: 0.329 ± 0.009	1.335HisAsp: 1.335 ± 0.016	1.272HisGlu: 1.272 ± 0.017	0.894HisPhe: 0.894 ± 0.012	1.755HisGly: 1.755 ± 0.019	0.967HisHis: 0.967 ± 0.021	1.023HisIle: 1.023 ± 0.016	0.861HisLys: 0.861 ± 0.013	2.158HisLeu: 2.158 ± 0.02	0.503HisMet: 0.503 ± 0.009	0.801HisAsn: 0.801 ± 0.013	1.638HisPro: 1.638 ± 0.021	1.041HisGln: 1.041 ± 0.019	1.572HisArg: 1.572 ± 0.021	1.665HisSer: 1.665 ± 0.02	1.186HisThr: 1.186 ± 0.015	1.498HisVal: 1.498 ± 0.018	0.339HisTrp: 0.339 ± 0.008	0.661HisTyr: 0.661 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.978IleAla: 3.978 ± 0.035	0.629IleCys: 0.629 ± 0.011	2.611IleAsp: 2.611 ± 0.028	2.545IleGlu: 2.545 ± 0.025	1.78IlePhe: 1.78 ± 0.021	3.026IleGly: 3.026 ± 0.027	1.067IleHis: 1.067 ± 0.016	2.167IleIle: 2.167 ± 0.025	1.965IleLys: 1.965 ± 0.019	4.046IleLeu: 4.046 ± 0.034	0.952IleMet: 0.952 ± 0.015	1.585IleAsn: 1.585 ± 0.019	2.775IlePro: 2.775 ± 0.022	1.65IleGln: 1.65 ± 0.019	2.658IleArg: 2.658 ± 0.023	3.267IleSer: 3.267 ± 0.029	2.58IleThr: 2.58 ± 0.026	3.099IleVal: 3.099 ± 0.025	0.666IleTrp: 0.666 ± 0.011	1.227IleTyr: 1.227 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.332LysAla: 4.332 ± 0.033	0.464LysCys: 0.464 ± 0.012	2.66LysAsp: 2.66 ± 0.029	3.102LysGlu: 3.102 ± 0.03	1.337LysPhe: 1.337 ± 0.018	2.957LysGly: 2.957 ± 0.029	1.062LysHis: 1.062 ± 0.016	2.035LysIle: 2.035 ± 0.021	3.339LysLys: 3.339 ± 0.045	3.798LysLeu: 3.798 ± 0.032	1.013LysMet: 1.013 ± 0.013	1.647LysAsn: 1.647 ± 0.021	2.724LysPro: 2.724 ± 0.029	1.72LysGln: 1.72 ± 0.019	3.233LysArg: 3.233 ± 0.027	3.222LysSer: 3.222 ± 0.028	2.89LysThr: 2.89 ± 0.026	2.7LysVal: 2.7 ± 0.026	0.651LysTrp: 0.651 ± 0.01	1.252LysTyr: 1.252 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.345LeuAla: 8.345 ± 0.047	1.119LeuCys: 1.119 ± 0.016	5.083LeuAsp: 5.083 ± 0.035	5.222LeuGlu: 5.222 ± 0.033	3.206LeuPhe: 3.206 ± 0.03	6.168LeuGly: 6.168 ± 0.041	2.075LeuHis: 2.075 ± 0.021	3.398LeuIle: 3.398 ± 0.033	3.856LeuLys: 3.856 ± 0.036	7.957LeuLeu: 7.957 ± 0.053	1.719LeuMet: 1.719 ± 0.019	2.838LeuAsn: 2.838 ± 0.025	5.503LeuPro: 5.503 ± 0.061	3.489LeuGln: 3.489 ± 0.03	5.869LeuArg: 5.869 ± 0.045	6.8LeuSer: 6.8 ± 0.045	4.751LeuThr: 4.751 ± 0.034	5.718LeuVal: 5.718 ± 0.043	1.199LeuTrp: 1.199 ± 0.016	2.165LeuTyr: 2.165 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.417MetAla: 2.417 ± 0.023	0.227MetCys: 0.227 ± 0.006	1.248MetAsp: 1.248 ± 0.015	1.215MetGlu: 1.215 ± 0.016	0.746MetPhe: 0.746 ± 0.011	1.487MetGly: 1.487 ± 0.022	0.453MetHis: 0.453 ± 0.009	0.894MetIle: 0.894 ± 0.013	0.967MetLys: 0.967 ± 0.015	1.808MetLeu: 1.808 ± 0.02	0.602MetMet: 0.602 ± 0.011	0.749MetAsn: 0.749 ± 0.013	1.349MetPro: 1.349 ± 0.017	0.81MetGln: 0.81 ± 0.014	1.329MetArg: 1.329 ± 0.017	1.875MetSer: 1.875 ± 0.02	1.353MetThr: 1.353 ± 0.016	1.319MetVal: 1.319 ± 0.017	0.266MetTrp: 0.266 ± 0.008	0.51MetTyr: 0.51 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.114AsnAla: 3.114 ± 0.026	0.419AsnCys: 0.419 ± 0.009	1.927AsnAsp: 1.927 ± 0.018	1.845AsnGlu: 1.845 ± 0.02	1.285AsnPhe: 1.285 ± 0.017	3.024AsnGly: 3.024 ± 0.03	0.807AsnHis: 0.807 ± 0.013	1.795AsnIle: 1.795 ± 0.02	1.476AsnLys: 1.476 ± 0.018	3.049AsnLeu: 3.049 ± 0.027	0.826AsnMet: 0.826 ± 0.013	1.54AsnAsn: 1.54 ± 0.031	2.398AsnPro: 2.398 ± 0.021	1.218AsnGln: 1.218 ± 0.019	1.886AsnArg: 1.886 ± 0.021	2.509AsnSer: 2.509 ± 0.023	2.077AsnThr: 2.077 ± 0.022	2.263AsnVal: 2.263 ± 0.022	0.529AsnTrp: 0.529 ± 0.01	0.976AsnTyr: 0.976 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	6.197ProAla: 6.197 ± 0.057	0.5ProCys: 0.5 ± 0.012	3.394ProAsp: 3.394 ± 0.026	3.929ProGlu: 3.929 ± 0.035	2.073ProPhe: 2.073 ± 0.02	4.362ProGly: 4.362 ± 0.041	1.314ProHis: 1.314 ± 0.019	2.331ProIle: 2.331 ± 0.023	2.628ProLys: 2.628 ± 0.027	4.73ProLeu: 4.73 ± 0.036	1.12ProMet: 1.12 ± 0.016	2.106ProAsn: 2.106 ± 0.021	5.79ProPro: 5.79 ± 0.093	2.469ProGln: 2.469 ± 0.034	3.754ProArg: 3.754 ± 0.031	5.934ProSer: 5.934 ± 0.068	4.081ProThr: 4.081 ± 0.043	3.937ProVal: 3.937 ± 0.033	0.773ProTrp: 0.773 ± 0.012	1.439ProTyr: 1.439 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.477GlnAla: 3.477 ± 0.03	0.416GlnCys: 0.416 ± 0.009	1.994GlnAsp: 1.994 ± 0.023	2.185GlnGlu: 2.185 ± 0.021	1.196GlnPhe: 1.196 ± 0.015	2.4GlnGly: 2.4 ± 0.025	1.127GlnHis: 1.127 ± 0.017	1.676GlnIle: 1.676 ± 0.018	1.816GlnLys: 1.816 ± 0.02	3.216GlnLeu: 3.216 ± 0.027	0.881GlnMet: 0.881 ± 0.016	1.36GlnAsn: 1.36 ± 0.017	2.574GlnPro: 2.574 ± 0.032	3.032GlnGln: 3.032 ± 0.071	2.623GlnArg: 2.623 ± 0.029	2.836GlnSer: 2.836 ± 0.023	2.303GlnThr: 2.303 ± 0.034	2.115GlnVal: 2.115 ± 0.02	0.538GlnTrp: 0.538 ± 0.01	1.061GlnTyr: 1.061 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.108ArgAla: 5.108 ± 0.035	0.748ArgCys: 0.748 ± 0.013	3.69ArgAsp: 3.69 ± 0.033	3.896ArgGlu: 3.896 ± 0.033	2.183ArgPhe: 2.183 ± 0.02	4.129ArgGly: 4.129 ± 0.033	1.653ArgHis: 1.653 ± 0.02	2.714ArgIle: 2.714 ± 0.023	3.306ArgLys: 3.306 ± 0.033	5.608ArgLeu: 5.608 ± 0.041	1.351ArgMet: 1.351 ± 0.018	2.215ArgAsn: 2.215 ± 0.02	3.927ArgPro: 3.927 ± 0.035	2.663ArgGln: 2.663 ± 0.025	5.599ArgArg: 5.599 ± 0.051	4.789ArgSer: 4.789 ± 0.041	3.376ArgThr: 3.376 ± 0.025	3.602ArgVal: 3.602 ± 0.029	0.961ArgTrp: 0.961 ± 0.012	1.604ArgTyr: 1.604 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.992SerAla: 6.992 ± 0.041	0.835SerCys: 0.835 ± 0.013	4.074SerAsp: 4.074 ± 0.034	3.815SerGlu: 3.815 ± 0.037	2.933SerPhe: 2.933 ± 0.025	5.646SerGly: 5.646 ± 0.049	1.817SerHis: 1.817 ± 0.02	3.531SerIle: 3.531 ± 0.033	3.396SerLys: 3.396 ± 0.031	6.796SerLeu: 6.796 ± 0.051	1.66SerMet: 1.66 ± 0.019	2.742SerAsn: 2.742 ± 0.023	5.542SerPro: 5.542 ± 0.053	3.05SerGln: 3.05 ± 0.032	5.071SerArg: 5.071 ± 0.043	8.483SerSer: 8.483 ± 0.089	5.256SerThr: 5.256 ± 0.071	4.713SerVal: 4.713 ± 0.043	1.098SerTrp: 1.098 ± 0.015	1.936SerTyr: 1.936 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.756ThrAla: 5.756 ± 0.04	0.721ThrCys: 0.721 ± 0.013	2.849ThrAsp: 2.849 ± 0.023	3.064ThrGlu: 3.064 ± 0.029	2.161ThrPhe: 2.161 ± 0.022	4.312ThrGly: 4.312 ± 0.053	1.215ThrHis: 1.215 ± 0.016	2.862ThrIle: 2.862 ± 0.028	2.517ThrLys: 2.517 ± 0.026	5.035ThrLeu: 5.035 ± 0.04	1.202ThrMet: 1.202 ± 0.016	2.044ThrAsn: 2.044 ± 0.021	4.509ThrPro: 4.509 ± 0.045	2.014ThrGln: 2.014 ± 0.021	3.259ThrArg: 3.259 ± 0.023	5.093ThrSer: 5.093 ± 0.073	4.629ThrThr: 4.629 ± 0.092	3.928ThrVal: 3.928 ± 0.069	0.866ThrTrp: 0.866 ± 0.014	1.56ThrTyr: 1.56 ± 0.02	0.001ThrXaa: 0.001 ± 0.0
Val	6.063ValAla: 6.063 ± 0.038	0.829ValCys: 0.829 ± 0.012	3.986ValAsp: 3.986 ± 0.031	3.971ValGlu: 3.971 ± 0.037	2.636ValPhe: 2.636 ± 0.029	4.361ValGly: 4.361 ± 0.035	1.382ValHis: 1.382 ± 0.017	2.835ValIle: 2.835 ± 0.03	2.854ValLys: 2.854 ± 0.03	5.807ValLeu: 5.807 ± 0.045	1.344ValMet: 1.344 ± 0.015	2.205ValAsn: 2.205 ± 0.019	3.946ValPro: 3.946 ± 0.045	2.289ValGln: 2.289 ± 0.02	3.754ValArg: 3.754 ± 0.027	4.754ValSer: 4.754 ± 0.037	3.778ValThr: 3.778 ± 0.053	4.953ValVal: 4.953 ± 0.054	0.949ValTrp: 0.949 ± 0.016	1.753ValTyr: 1.753 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.225TrpAla: 1.225 ± 0.017	0.196TrpCys: 0.196 ± 0.006	0.933TrpAsp: 0.933 ± 0.014	0.842TrpGlu: 0.842 ± 0.013	0.56TrpPhe: 0.56 ± 0.011	0.976TrpGly: 0.976 ± 0.015	0.377TrpHis: 0.377 ± 0.008	0.691TrpIle: 0.691 ± 0.01	0.743TrpLys: 0.743 ± 0.012	1.343TrpLeu: 1.343 ± 0.017	0.371TrpMet: 0.371 ± 0.008	0.626TrpAsn: 0.626 ± 0.013	0.647TrpPro: 0.647 ± 0.013	0.554TrpGln: 0.554 ± 0.01	0.999TrpArg: 0.999 ± 0.012	1.033TrpSer: 1.033 ± 0.014	0.938TrpThr: 0.938 ± 0.013	0.92TrpVal: 0.92 ± 0.013	0.293TrpTrp: 0.293 ± 0.008	0.434TrpTyr: 0.434 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.146TyrAla: 2.146 ± 0.021	0.397TyrCys: 0.397 ± 0.009	1.643TyrAsp: 1.643 ± 0.016	1.456TyrGlu: 1.456 ± 0.018	1.14TyrPhe: 1.14 ± 0.016	2.063TyrGly: 2.063 ± 0.024	0.714TyrHis: 0.714 ± 0.012	1.211TyrIle: 1.211 ± 0.014	1.013TyrLys: 1.013 ± 0.015	2.453TyrLeu: 2.453 ± 0.026	0.586TyrMet: 0.586 ± 0.011	1.043TyrAsn: 1.043 ± 0.015	1.408TyrPro: 1.408 ± 0.019	1.008TyrGln: 1.008 ± 0.016	1.597TyrArg: 1.597 ± 0.019	1.858TyrSer: 1.858 ± 0.021	1.506TyrThr: 1.506 ± 0.021	1.667TyrVal: 1.667 ± 0.02	0.438TyrTrp: 0.438 ± 0.008	0.86TyrTyr: 0.86 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.034XaaXaa: 0.034 ± 0.011

Statistics based on 11847 proteins (5593092 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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