Amino acid dipepetide frequency for Luteococcus japonicus LSP_Lj1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.241AlaAla: 16.241 ± 0.175	1.139AlaCys: 1.139 ± 0.034	7.16AlaAsp: 7.16 ± 0.096	7.428AlaGlu: 7.428 ± 0.105	3.222AlaPhe: 3.222 ± 0.059	11.087AlaGly: 11.087 ± 0.112	2.721AlaHis: 2.721 ± 0.06	4.779AlaIle: 4.779 ± 0.088	3.505AlaLys: 3.505 ± 0.078	12.937AlaLeu: 12.937 ± 0.15	3.382AlaMet: 3.382 ± 0.073	2.475AlaAsn: 2.475 ± 0.048	5.651AlaPro: 5.651 ± 0.089	4.454AlaGln: 4.454 ± 0.072	8.466AlaArg: 8.466 ± 0.097	6.712AlaSer: 6.712 ± 0.101	7.19AlaThr: 7.19 ± 0.097	9.871AlaVal: 9.871 ± 0.11	2.02AlaTrp: 2.02 ± 0.054	1.957AlaTyr: 1.957 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.966CysAla: 0.966 ± 0.032	0.152CysCys: 0.152 ± 0.013	0.521CysAsp: 0.521 ± 0.025	0.435CysGlu: 0.435 ± 0.024	0.284CysPhe: 0.284 ± 0.016	1.012CysGly: 1.012 ± 0.036	0.257CysHis: 0.257 ± 0.015	0.294CysIle: 0.294 ± 0.015	0.159CysLys: 0.159 ± 0.012	0.913CysLeu: 0.913 ± 0.034	0.167CysMet: 0.167 ± 0.013	0.169CysAsn: 0.169 ± 0.014	0.599CysPro: 0.599 ± 0.027	0.28CysGln: 0.28 ± 0.018	0.589CysArg: 0.589 ± 0.024	0.555CysSer: 0.555 ± 0.026	0.567CysThr: 0.567 ± 0.023	0.649CysVal: 0.649 ± 0.025	0.169CysTrp: 0.169 ± 0.014	0.155CysTyr: 0.155 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.198AspAla: 7.198 ± 0.099	0.412AspCys: 0.412 ± 0.02	3.677AspAsp: 3.677 ± 0.081	4.987AspGlu: 4.987 ± 0.076	1.846AspPhe: 1.846 ± 0.044	5.792AspGly: 5.792 ± 0.092	1.459AspHis: 1.459 ± 0.042	2.07AspIle: 2.07 ± 0.049	1.597AspLys: 1.597 ± 0.048	6.289AspLeu: 6.289 ± 0.09	1.08AspMet: 1.08 ± 0.033	1.029AspAsn: 1.029 ± 0.039	3.827AspPro: 3.827 ± 0.069	2.117AspGln: 2.117 ± 0.055	3.876AspArg: 3.876 ± 0.07	2.524AspSer: 2.524 ± 0.055	2.34AspThr: 2.34 ± 0.05	4.93AspVal: 4.93 ± 0.068	0.916AspTrp: 0.916 ± 0.032	1.135AspTyr: 1.135 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.378GluAla: 7.378 ± 0.107	0.415GluCys: 0.415 ± 0.022	2.863GluAsp: 2.863 ± 0.054	3.02GluGlu: 3.02 ± 0.066	1.446GluPhe: 1.446 ± 0.041	4.259GluGly: 4.259 ± 0.074	1.679GluHis: 1.679 ± 0.042	2.311GluIle: 2.311 ± 0.056	1.734GluLys: 1.734 ± 0.052	7.01GluLeu: 7.01 ± 0.091	1.315GluMet: 1.315 ± 0.037	1.251GluAsn: 1.251 ± 0.038	2.903GluPro: 2.903 ± 0.057	2.887GluGln: 2.887 ± 0.066	4.739GluArg: 4.739 ± 0.08	2.484GluSer: 2.484 ± 0.055	2.717GluThr: 2.717 ± 0.056	5.315GluVal: 5.315 ± 0.077	0.779GluTrp: 0.779 ± 0.032	0.942GluTyr: 0.942 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.475PheAla: 3.475 ± 0.065	0.348PheCys: 0.348 ± 0.018	2.063PheAsp: 2.063 ± 0.048	1.594PheGlu: 1.594 ± 0.039	0.995PhePhe: 0.995 ± 0.037	3.202PheGly: 3.202 ± 0.055	0.634PheHis: 0.634 ± 0.026	1.051PheIle: 1.051 ± 0.034	0.654PheLys: 0.654 ± 0.029	2.605PheLeu: 2.605 ± 0.056	0.552PheMet: 0.552 ± 0.023	0.746PheAsn: 0.746 ± 0.03	1.272PhePro: 1.272 ± 0.032	0.72PheGln: 0.72 ± 0.03	1.539PheArg: 1.539 ± 0.036	1.645PheSer: 1.645 ± 0.038	2.081PheThr: 2.081 ± 0.045	2.493PheVal: 2.493 ± 0.052	0.474PheTrp: 0.474 ± 0.023	0.561PheTyr: 0.561 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	9.37GlyAla: 9.37 ± 0.122	0.978GlyCys: 0.978 ± 0.033	4.63GlyAsp: 4.63 ± 0.08	4.776GlyGlu: 4.776 ± 0.076	3.038GlyPhe: 3.038 ± 0.054	7.185GlyGly: 7.185 ± 0.11	2.251GlyHis: 2.251 ± 0.055	4.419GlyIle: 4.419 ± 0.075	2.992GlyLys: 2.992 ± 0.06	9.654GlyLeu: 9.654 ± 0.117	2.449GlyMet: 2.449 ± 0.058	2.028GlyAsn: 2.028 ± 0.045	3.851GlyPro: 3.851 ± 0.062	3.336GlyGln: 3.336 ± 0.062	6.618GlyArg: 6.618 ± 0.098	5.258GlySer: 5.258 ± 0.076	5.229GlyThr: 5.229 ± 0.077	7.125GlyVal: 7.125 ± 0.099	1.944GlyTrp: 1.944 ± 0.058	2.091GlyTyr: 2.091 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.481HisAla: 2.481 ± 0.052	0.24HisCys: 0.24 ± 0.015	1.581HisAsp: 1.581 ± 0.039	1.383HisGlu: 1.383 ± 0.039	0.682HisPhe: 0.682 ± 0.028	2.304HisGly: 2.304 ± 0.045	0.814HisHis: 0.814 ± 0.032	0.795HisIle: 0.795 ± 0.031	0.427HisLys: 0.427 ± 0.018	2.574HisLeu: 2.574 ± 0.056	0.419HisMet: 0.419 ± 0.022	0.459HisAsn: 0.459 ± 0.023	1.751HisPro: 1.751 ± 0.05	0.873HisGln: 0.873 ± 0.031	1.874HisArg: 1.874 ± 0.053	1.099HisSer: 1.099 ± 0.032	1.208HisThr: 1.208 ± 0.039	1.947HisVal: 1.947 ± 0.046	0.393HisTrp: 0.393 ± 0.021	0.465HisTyr: 0.465 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.184IleAla: 5.184 ± 0.082	0.415IleCys: 0.415 ± 0.022	2.815IleAsp: 2.815 ± 0.057	2.356IleGlu: 2.356 ± 0.05	1.193IlePhe: 1.193 ± 0.035	4.012IleGly: 4.012 ± 0.077	0.844IleHis: 0.844 ± 0.026	1.635IleIle: 1.635 ± 0.042	1.079IleLys: 1.079 ± 0.039	3.065IleLeu: 3.065 ± 0.062	0.764IleMet: 0.764 ± 0.03	0.996IleAsn: 0.996 ± 0.035	2.224IlePro: 2.224 ± 0.048	0.971IleGln: 0.971 ± 0.029	2.303IleArg: 2.303 ± 0.047	2.283IleSer: 2.283 ± 0.051	2.861IleThr: 2.861 ± 0.055	3.207IleVal: 3.207 ± 0.067	0.486IleTrp: 0.486 ± 0.025	0.72IleTyr: 0.72 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.662LysAla: 3.662 ± 0.08	0.137LysCys: 0.137 ± 0.011	1.624LysAsp: 1.624 ± 0.048	1.32LysGlu: 1.32 ± 0.041	0.634LysPhe: 0.634 ± 0.029	2.299LysGly: 2.299 ± 0.053	0.588LysHis: 0.588 ± 0.022	1.088LysIle: 1.088 ± 0.039	1.157LysLys: 1.157 ± 0.047	2.497LysLeu: 2.497 ± 0.062	0.669LysMet: 0.669 ± 0.026	0.73LysAsn: 0.73 ± 0.031	1.629LysPro: 1.629 ± 0.051	1.084LysGln: 1.084 ± 0.037	1.698LysArg: 1.698 ± 0.048	1.329LysSer: 1.329 ± 0.043	1.598LysThr: 1.598 ± 0.05	2.385LysVal: 2.385 ± 0.055	0.315LysTrp: 0.315 ± 0.016	0.549LysTyr: 0.549 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.604LeuAla: 14.604 ± 0.169	0.9LeuCys: 0.9 ± 0.03	6.868LeuAsp: 6.868 ± 0.091	5.391LeuGlu: 5.391 ± 0.074	2.741LeuPhe: 2.741 ± 0.055	9.593LeuGly: 9.593 ± 0.106	2.172LeuHis: 2.172 ± 0.054	3.045LeuIle: 3.045 ± 0.062	2.331LeuLys: 2.331 ± 0.062	10.498LeuLeu: 10.498 ± 0.161	2.23LeuMet: 2.23 ± 0.052	1.906LeuAsn: 1.906 ± 0.042	5.655LeuPro: 5.655 ± 0.076	2.851LeuGln: 2.851 ± 0.061	7.168LeuArg: 7.168 ± 0.09	5.369LeuSer: 5.369 ± 0.064	6.267LeuThr: 6.267 ± 0.077	10.541LeuVal: 10.541 ± 0.133	1.307LeuTrp: 1.307 ± 0.039	1.488LeuTyr: 1.488 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	3.136MetAla: 3.136 ± 0.058	0.178MetCys: 0.178 ± 0.012	1.213MetAsp: 1.213 ± 0.036	1.04MetGlu: 1.04 ± 0.038	0.596MetPhe: 0.596 ± 0.027	2.114MetGly: 2.114 ± 0.055	0.462MetHis: 0.462 ± 0.023	0.974MetIle: 0.974 ± 0.035	0.639MetLys: 0.639 ± 0.028	2.351MetLeu: 2.351 ± 0.057	0.629MetMet: 0.629 ± 0.028	0.677MetAsn: 0.677 ± 0.024	1.334MetPro: 1.334 ± 0.034	0.669MetGln: 0.669 ± 0.025	1.63MetArg: 1.63 ± 0.037	1.701MetSer: 1.701 ± 0.039	1.859MetThr: 1.859 ± 0.041	2.124MetVal: 2.124 ± 0.045	0.265MetTrp: 0.265 ± 0.019	0.334MetTyr: 0.334 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.449AsnAla: 2.449 ± 0.049	0.189AsnCys: 0.189 ± 0.013	1.181AsnAsp: 1.181 ± 0.042	1.067AsnGlu: 1.067 ± 0.035	0.676AsnPhe: 0.676 ± 0.027	1.938AsnGly: 1.938 ± 0.05	0.605AsnHis: 0.605 ± 0.025	0.836AsnIle: 0.836 ± 0.031	0.642AsnLys: 0.642 ± 0.025	2.224AsnLeu: 2.224 ± 0.042	0.484AsnMet: 0.484 ± 0.024	0.598AsnAsn: 0.598 ± 0.033	1.774AsnPro: 1.774 ± 0.041	0.829AsnGln: 0.829 ± 0.03	1.439AsnArg: 1.439 ± 0.038	1.204AsnSer: 1.204 ± 0.04	1.22AsnThr: 1.22 ± 0.036	1.62AsnVal: 1.62 ± 0.044	0.328AsnTrp: 0.328 ± 0.018	0.531AsnTyr: 0.531 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.503ProAla: 6.503 ± 0.092	0.393ProCys: 0.393 ± 0.018	3.693ProAsp: 3.693 ± 0.065	3.9ProGlu: 3.9 ± 0.074	1.384ProPhe: 1.384 ± 0.036	5.213ProGly: 5.213 ± 0.08	1.29ProHis: 1.29 ± 0.032	1.732ProIle: 1.732 ± 0.043	1.385ProLys: 1.385 ± 0.044	4.669ProLeu: 4.669 ± 0.064	1.297ProMet: 1.297 ± 0.035	1.049ProAsn: 1.049 ± 0.031	2.067ProPro: 2.067 ± 0.055	1.957ProGln: 1.957 ± 0.044	3.411ProArg: 3.411 ± 0.069	3.324ProSer: 3.324 ± 0.061	3.458ProThr: 3.458 ± 0.056	4.957ProVal: 4.957 ± 0.081	0.909ProTrp: 0.909 ± 0.029	0.96ProTyr: 0.96 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.754GlnAla: 4.754 ± 0.072	0.249GlnCys: 0.249 ± 0.015	1.564GlnAsp: 1.564 ± 0.047	1.728GlnGlu: 1.728 ± 0.04	0.831GlnPhe: 0.831 ± 0.032	2.799GlnGly: 2.799 ± 0.053	0.817GlnHis: 0.817 ± 0.029	1.504GlnIle: 1.504 ± 0.042	0.832GlnLys: 0.832 ± 0.033	3.924GlnLeu: 3.924 ± 0.066	0.897GlnMet: 0.897 ± 0.028	0.713GlnAsn: 0.713 ± 0.028	2.076GlnPro: 2.076 ± 0.051	1.708GlnGln: 1.708 ± 0.041	2.712GlnArg: 2.712 ± 0.065	1.436GlnSer: 1.436 ± 0.036	1.956GlnThr: 1.956 ± 0.045	3.41GlnVal: 3.41 ± 0.063	0.597GlnTrp: 0.597 ± 0.023	0.621GlnTyr: 0.621 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	7.797ArgAla: 7.797 ± 0.098	0.572ArgCys: 0.572 ± 0.025	3.813ArgAsp: 3.813 ± 0.065	4.39ArgGlu: 4.39 ± 0.076	2.042ArgPhe: 2.042 ± 0.042	5.372ArgGly: 5.372 ± 0.089	1.852ArgHis: 1.852 ± 0.053	3.39ArgIle: 3.39 ± 0.056	1.787ArgLys: 1.787 ± 0.049	7.276ArgLeu: 7.276 ± 0.097	1.992ArgMet: 1.992 ± 0.044	1.595ArgAsn: 1.595 ± 0.043	3.825ArgPro: 3.825 ± 0.07	2.568ArgGln: 2.568 ± 0.054	6.64ArgArg: 6.64 ± 0.118	3.806ArgSer: 3.806 ± 0.069	4.259ArgThr: 4.259 ± 0.069	5.506ArgVal: 5.506 ± 0.083	1.216ArgTrp: 1.216 ± 0.034	1.361ArgTyr: 1.361 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.016SerAla: 6.016 ± 0.091	0.445SerCys: 0.445 ± 0.024	2.789SerAsp: 2.789 ± 0.055	2.588SerGlu: 2.588 ± 0.057	1.735SerPhe: 1.735 ± 0.04	5.35SerGly: 5.35 ± 0.072	1.289SerHis: 1.289 ± 0.038	2.224SerIle: 2.224 ± 0.047	1.429SerLys: 1.429 ± 0.043	5.362SerLeu: 5.362 ± 0.078	1.496SerMet: 1.496 ± 0.039	1.227SerAsn: 1.227 ± 0.046	3.081SerPro: 3.081 ± 0.06	1.866SerGln: 1.866 ± 0.049	3.955SerArg: 3.955 ± 0.065	3.591SerSer: 3.591 ± 0.071	3.643SerThr: 3.643 ± 0.064	4.198SerVal: 4.198 ± 0.077	0.989SerTrp: 0.989 ± 0.03	1.158SerTyr: 1.158 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	6.882ThrAla: 6.882 ± 0.097	0.534ThrCys: 0.534 ± 0.024	3.462ThrAsp: 3.462 ± 0.058	2.987ThrGlu: 2.987 ± 0.054	1.67ThrPhe: 1.67 ± 0.038	5.748ThrGly: 5.748 ± 0.086	1.361ThrHis: 1.361 ± 0.041	2.6ThrIle: 2.6 ± 0.06	1.547ThrLys: 1.547 ± 0.044	5.654ThrLeu: 5.654 ± 0.069	1.391ThrMet: 1.391 ± 0.038	1.368ThrAsn: 1.368 ± 0.04	3.956ThrPro: 3.956 ± 0.073	1.88ThrGln: 1.88 ± 0.043	3.859ThrArg: 3.859 ± 0.068	3.688ThrSer: 3.688 ± 0.062	4.129ThrThr: 4.129 ± 0.073	5.274ThrVal: 5.274 ± 0.083	1.013ThrTrp: 1.013 ± 0.032	1.107ThrTyr: 1.107 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	10.719ValAla: 10.719 ± 0.13	0.834ValCys: 0.834 ± 0.029	5.712ValAsp: 5.712 ± 0.078	5.336ValGlu: 5.336 ± 0.084	2.44ValPhe: 2.44 ± 0.056	7.066ValGly: 7.066 ± 0.092	1.883ValHis: 1.883 ± 0.041	3.454ValIle: 3.454 ± 0.067	2.22ValLys: 2.22 ± 0.05	9.316ValLeu: 9.316 ± 0.118	1.984ValMet: 1.984 ± 0.051	1.988ValAsn: 1.988 ± 0.053	4.304ValPro: 4.304 ± 0.071	2.726ValGln: 2.726 ± 0.055	5.773ValArg: 5.773 ± 0.08	4.46ValSer: 4.46 ± 0.081	5.49ValThr: 5.49 ± 0.074	8.814ValVal: 8.814 ± 0.111	1.197ValTrp: 1.197 ± 0.033	1.25ValTyr: 1.25 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.67TrpAla: 1.67 ± 0.047	0.183TrpCys: 0.183 ± 0.013	0.699TrpAsp: 0.699 ± 0.03	0.689TrpGlu: 0.689 ± 0.026	0.606TrpPhe: 0.606 ± 0.023	1.118TrpGly: 1.118 ± 0.037	0.428TrpHis: 0.428 ± 0.021	0.634TrpIle: 0.634 ± 0.024	0.434TrpLys: 0.434 ± 0.021	2.027TrpLeu: 2.027 ± 0.056	0.44TrpMet: 0.44 ± 0.023	0.412TrpAsn: 0.412 ± 0.02	0.828TrpPro: 0.828 ± 0.032	0.734TrpGln: 0.734 ± 0.025	1.27TrpArg: 1.27 ± 0.036	1.0TrpSer: 1.0 ± 0.034	1.018TrpThr: 1.018 ± 0.035	1.159TrpVal: 1.159 ± 0.037	0.386TrpTrp: 0.386 ± 0.021	0.302TrpTyr: 0.302 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.912TyrAla: 1.912 ± 0.041	0.179TyrCys: 0.179 ± 0.013	1.174TyrAsp: 1.174 ± 0.032	1.03TyrGlu: 1.03 ± 0.036	0.642TyrPhe: 0.642 ± 0.024	1.758TyrGly: 1.758 ± 0.041	0.362TyrHis: 0.362 ± 0.02	0.579TyrIle: 0.579 ± 0.028	0.443TyrLys: 0.443 ± 0.022	2.081TyrLeu: 2.081 ± 0.048	0.286TyrMet: 0.286 ± 0.019	0.416TyrAsn: 0.416 ± 0.021	0.945TyrPro: 0.945 ± 0.033	0.618TyrGln: 0.618 ± 0.025	1.501TyrArg: 1.501 ± 0.041	0.964TyrSer: 0.964 ± 0.032	1.021TyrThr: 1.021 ± 0.035	1.441TyrVal: 1.441 ± 0.038	0.334TyrTrp: 0.334 ± 0.021	0.407TyrTyr: 0.407 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3244 proteins (992894 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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