Amino acid dipepetide frequency for Pararobbsia silviterrae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.095AlaAla: 17.095 ± 0.137	1.373AlaCys: 1.373 ± 0.031	7.04AlaAsp: 7.04 ± 0.07	5.777AlaGlu: 5.777 ± 0.07	4.545AlaPhe: 4.545 ± 0.054	10.018AlaGly: 10.018 ± 0.103	3.319AlaHis: 3.319 ± 0.054	6.33AlaIle: 6.33 ± 0.061	3.469AlaLys: 3.469 ± 0.059	14.546AlaLeu: 14.546 ± 0.114	3.219AlaMet: 3.219 ± 0.044	3.319AlaAsn: 3.319 ± 0.049	6.164AlaPro: 6.164 ± 0.088	5.299AlaGln: 5.299 ± 0.072	9.911AlaArg: 9.911 ± 0.104	8.56AlaSer: 8.56 ± 0.099	6.647AlaThr: 6.647 ± 0.087	8.594AlaVal: 8.594 ± 0.073	1.758AlaTrp: 1.758 ± 0.033	2.787AlaTyr: 2.787 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	1.273CysAla: 1.273 ± 0.028	0.111CysCys: 0.111 ± 0.008	0.548CysAsp: 0.548 ± 0.02	0.448CysGlu: 0.448 ± 0.016	0.306CysPhe: 0.306 ± 0.013	0.929CysGly: 0.929 ± 0.024	0.209CysHis: 0.209 ± 0.012	0.384CysIle: 0.384 ± 0.014	0.176CysLys: 0.176 ± 0.01	0.748CysLeu: 0.748 ± 0.02	0.196CysMet: 0.196 ± 0.011	0.19CysAsn: 0.19 ± 0.011	0.401CysPro: 0.401 ± 0.015	0.181CysGln: 0.181 ± 0.01	0.602CysArg: 0.602 ± 0.018	0.47CysSer: 0.47 ± 0.017	0.434CysThr: 0.434 ± 0.016	0.841CysVal: 0.841 ± 0.023	0.111CysTrp: 0.111 ± 0.008	0.203CysTyr: 0.203 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	9.272AspAla: 9.272 ± 0.086	0.415AspCys: 0.415 ± 0.016	3.601AspAsp: 3.601 ± 0.047	3.288AspGlu: 3.288 ± 0.054	1.973AspPhe: 1.973 ± 0.038	4.892AspGly: 4.892 ± 0.059	1.281AspHis: 1.281 ± 0.031	2.814AspIle: 2.814 ± 0.04	1.463AspLys: 1.463 ± 0.031	5.345AspLeu: 5.345 ± 0.06	1.112AspMet: 1.112 ± 0.022	1.319AspAsn: 1.319 ± 0.032	3.27AspPro: 3.27 ± 0.045	1.535AspGln: 1.535 ± 0.034	3.9AspArg: 3.9 ± 0.056	2.509AspSer: 2.509 ± 0.041	3.333AspThr: 3.333 ± 0.049	4.76AspVal: 4.76 ± 0.059	0.971AspTrp: 0.971 ± 0.021	1.54AspTyr: 1.54 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	6.168GluAla: 6.168 ± 0.078	0.365GluCys: 0.365 ± 0.016	2.132GluAsp: 2.132 ± 0.039	1.812GluGlu: 1.812 ± 0.039	1.672GluPhe: 1.672 ± 0.032	3.255GluGly: 3.255 ± 0.048	1.601GluHis: 1.601 ± 0.034	2.885GluIle: 2.885 ± 0.046	1.392GluLys: 1.392 ± 0.034	4.974GluLeu: 4.974 ± 0.061	1.077GluMet: 1.077 ± 0.03	1.265GluAsn: 1.265 ± 0.024	2.471GluPro: 2.471 ± 0.042	2.288GluGln: 2.288 ± 0.041	4.865GluArg: 4.865 ± 0.063	2.738GluSer: 2.738 ± 0.042	2.841GluThr: 2.841 ± 0.039	3.266GluVal: 3.266 ± 0.044	0.673GluTrp: 0.673 ± 0.019	1.117GluTyr: 1.117 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	4.65PheAla: 4.65 ± 0.052	0.373PheCys: 0.373 ± 0.015	2.903PheAsp: 2.903 ± 0.043	2.152PheGlu: 2.152 ± 0.035	1.27PhePhe: 1.27 ± 0.027	3.717PheGly: 3.717 ± 0.054	0.703PheHis: 0.703 ± 0.018	1.531PheIle: 1.531 ± 0.03	1.025PheLys: 1.025 ± 0.027	2.726PheLeu: 2.726 ± 0.042	0.765PheMet: 0.765 ± 0.019	1.124PheAsn: 1.124 ± 0.026	1.443PhePro: 1.443 ± 0.029	0.915PheGln: 0.915 ± 0.021	1.938PheArg: 1.938 ± 0.034	2.174PheSer: 2.174 ± 0.034	1.857PheThr: 1.857 ± 0.031	3.176PheVal: 3.176 ± 0.047	0.508PheTrp: 0.508 ± 0.016	0.932PheTyr: 0.932 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	9.949GlyAla: 9.949 ± 0.097	0.751GlyCys: 0.751 ± 0.023	4.272GlyAsp: 4.272 ± 0.051	3.968GlyGlu: 3.968 ± 0.054	3.293GlyPhe: 3.293 ± 0.045	6.631GlyGly: 6.631 ± 0.085	1.928GlyHis: 1.928 ± 0.039	4.409GlyIle: 4.409 ± 0.052	2.79GlyLys: 2.79 ± 0.051	8.195GlyLeu: 8.195 ± 0.079	1.997GlyMet: 1.997 ± 0.034	2.233GlyAsn: 2.233 ± 0.049	3.036GlyPro: 3.036 ± 0.044	2.624GlyGln: 2.624 ± 0.044	5.326GlyArg: 5.326 ± 0.055	4.574GlySer: 4.574 ± 0.074	5.033GlyThr: 5.033 ± 0.104	6.843GlyVal: 6.843 ± 0.068	1.285GlyTrp: 1.285 ± 0.03	2.4GlyTyr: 2.4 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	3.9HisAla: 3.9 ± 0.064	0.226HisCys: 0.226 ± 0.01	1.647HisAsp: 1.647 ± 0.032	1.251HisGlu: 1.251 ± 0.033	0.918HisPhe: 0.918 ± 0.021	2.204HisGly: 2.204 ± 0.042	0.661HisHis: 0.661 ± 0.023	0.969HisIle: 0.969 ± 0.023	0.476HisLys: 0.476 ± 0.017	2.182HisLeu: 2.182 ± 0.037	0.491HisMet: 0.491 ± 0.015	0.464HisAsn: 0.464 ± 0.019	1.455HisPro: 1.455 ± 0.033	0.621HisGln: 0.621 ± 0.017	1.704HisArg: 1.704 ± 0.035	1.015HisSer: 1.015 ± 0.025	1.149HisThr: 1.149 ± 0.028	1.916HisVal: 1.916 ± 0.031	0.386HisTrp: 0.386 ± 0.016	0.663HisTyr: 0.663 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	7.594IleAla: 7.594 ± 0.07	0.434IleCys: 0.434 ± 0.016	4.019IleAsp: 4.019 ± 0.046	3.548IleGlu: 3.548 ± 0.046	1.375IlePhe: 1.375 ± 0.029	5.168IleGly: 5.168 ± 0.066	1.028IleHis: 1.028 ± 0.025	1.576IleIle: 1.576 ± 0.031	1.34IleLys: 1.34 ± 0.029	3.289IleLeu: 3.289 ± 0.046	0.761IleMet: 0.761 ± 0.019	1.385IleAsn: 1.385 ± 0.031	2.141IlePro: 2.141 ± 0.032	1.341IleGln: 1.341 ± 0.024	3.116IleArg: 3.116 ± 0.044	2.628IleSer: 2.628 ± 0.042	2.44IleThr: 2.44 ± 0.045	4.754IleVal: 4.754 ± 0.066	0.56IleTrp: 0.56 ± 0.017	1.079IleTyr: 1.079 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.282LysAla: 3.282 ± 0.052	0.137LysCys: 0.137 ± 0.009	1.377LysAsp: 1.377 ± 0.034	1.082LysGlu: 1.082 ± 0.028	0.753LysPhe: 0.753 ± 0.021	1.955LysGly: 1.955 ± 0.035	0.707LysHis: 0.707 ± 0.02	1.565LysIle: 1.565 ± 0.032	0.998LysLys: 0.998 ± 0.032	2.907LysLeu: 2.907 ± 0.045	0.67LysMet: 0.67 ± 0.018	0.754LysAsn: 0.754 ± 0.025	1.743LysPro: 1.743 ± 0.036	1.18LysGln: 1.18 ± 0.03	2.177LysArg: 2.177 ± 0.04	1.58LysSer: 1.58 ± 0.03	1.792LysThr: 1.792 ± 0.036	2.049LysVal: 2.049 ± 0.038	0.333LysTrp: 0.333 ± 0.015	0.632LysTyr: 0.632 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	13.608LeuAla: 13.608 ± 0.109	0.97LeuCys: 0.97 ± 0.024	6.593LeuAsp: 6.593 ± 0.068	4.835LeuGlu: 4.835 ± 0.064	3.46LeuPhe: 3.46 ± 0.051	8.177LeuGly: 8.177 ± 0.081	2.207LeuHis: 2.207 ± 0.033	4.751LeuIle: 4.751 ± 0.061	3.013LeuLys: 3.013 ± 0.049	9.288LeuLeu: 9.288 ± 0.107	2.129LeuMet: 2.129 ± 0.037	2.757LeuAsn: 2.757 ± 0.039	5.234LeuPro: 5.234 ± 0.062	2.849LeuGln: 2.849 ± 0.043	6.923LeuArg: 6.923 ± 0.065	6.46LeuSer: 6.46 ± 0.068	5.678LeuThr: 5.678 ± 0.072	7.451LeuVal: 7.451 ± 0.076	1.047LeuTrp: 1.047 ± 0.029	2.089LeuTyr: 2.089 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.252MetAla: 2.252 ± 0.041	0.174MetCys: 0.174 ± 0.009	0.948MetAsp: 0.948 ± 0.023	0.763MetGlu: 0.763 ± 0.022	0.791MetPhe: 0.791 ± 0.022	1.465MetGly: 1.465 ± 0.033	0.596MetHis: 0.596 ± 0.021	1.139MetIle: 1.139 ± 0.024	0.834MetLys: 0.834 ± 0.022	2.606MetLeu: 2.606 ± 0.04	0.525MetMet: 0.525 ± 0.019	0.863MetAsn: 0.863 ± 0.024	1.453MetPro: 1.453 ± 0.027	0.893MetGln: 0.893 ± 0.023	1.905MetArg: 1.905 ± 0.033	1.7MetSer: 1.7 ± 0.031	1.698MetThr: 1.698 ± 0.029	1.363MetVal: 1.363 ± 0.027	0.184MetTrp: 0.184 ± 0.01	0.381MetTyr: 0.381 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.715AsnAla: 3.715 ± 0.052	0.214AsnCys: 0.214 ± 0.01	1.588AsnAsp: 1.588 ± 0.035	1.233AsnGlu: 1.233 ± 0.026	0.939AsnPhe: 0.939 ± 0.024	2.641AsnGly: 2.641 ± 0.052	0.528AsnHis: 0.528 ± 0.017	1.187AsnIle: 1.187 ± 0.029	0.621AsnLys: 0.621 ± 0.02	2.657AsnLeu: 2.657 ± 0.04	0.533AsnMet: 0.533 ± 0.017	0.779AsnAsn: 0.779 ± 0.024	1.722AsnPro: 1.722 ± 0.037	0.854AsnGln: 0.854 ± 0.023	1.689AsnArg: 1.689 ± 0.032	1.262AsnSer: 1.262 ± 0.029	1.577AsnThr: 1.577 ± 0.038	2.266AsnVal: 2.266 ± 0.041	0.393AsnTrp: 0.393 ± 0.015	0.722AsnTyr: 0.722 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	6.341ProAla: 6.341 ± 0.078	0.359ProCys: 0.359 ± 0.014	3.472ProAsp: 3.472 ± 0.052	2.743ProGlu: 2.743 ± 0.039	1.884ProPhe: 1.884 ± 0.035	3.89ProGly: 3.89 ± 0.051	1.312ProHis: 1.312 ± 0.026	2.344ProIle: 2.344 ± 0.035	1.357ProLys: 1.357 ± 0.027	4.736ProLeu: 4.736 ± 0.053	1.098ProMet: 1.098 ± 0.025	1.543ProAsn: 1.543 ± 0.032	2.357ProPro: 2.357 ± 0.049	1.585ProGln: 1.585 ± 0.034	3.083ProArg: 3.083 ± 0.055	3.165ProSer: 3.165 ± 0.047	2.818ProThr: 2.818 ± 0.041	4.186ProVal: 4.186 ± 0.057	0.659ProTrp: 0.659 ± 0.021	1.274ProTyr: 1.274 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.328GlnAla: 4.328 ± 0.055	0.263GlnCys: 0.263 ± 0.012	1.314GlnAsp: 1.314 ± 0.027	1.073GlnGlu: 1.073 ± 0.027	1.179GlnPhe: 1.179 ± 0.022	2.399GlnGly: 2.399 ± 0.043	0.877GlnHis: 0.877 ± 0.019	2.035GlnIle: 2.035 ± 0.034	0.956GlnLys: 0.956 ± 0.026	3.186GlnLeu: 3.186 ± 0.049	0.9GlnMet: 0.9 ± 0.024	0.916GlnAsn: 0.916 ± 0.023	1.701GlnPro: 1.701 ± 0.038	1.531GlnGln: 1.531 ± 0.046	2.763GlnArg: 2.763 ± 0.045	2.101GlnSer: 2.101 ± 0.037	2.229GlnThr: 2.229 ± 0.039	2.293GlnVal: 2.293 ± 0.046	0.539GlnTrp: 0.539 ± 0.017	0.885GlnTyr: 0.885 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	9.211ArgAla: 9.211 ± 0.097	0.606ArgCys: 0.606 ± 0.02	4.286ArgAsp: 4.286 ± 0.053	4.112ArgGlu: 4.112 ± 0.06	2.928ArgPhe: 2.928 ± 0.041	4.782ArgGly: 4.782 ± 0.052	2.019ArgHis: 2.019 ± 0.039	3.867ArgIle: 3.867 ± 0.058	1.978ArgLys: 1.978 ± 0.038	7.157ArgLeu: 7.157 ± 0.078	1.813ArgMet: 1.813 ± 0.032	1.788ArgAsn: 1.788 ± 0.032	3.085ArgPro: 3.085 ± 0.043	2.246ArgGln: 2.246 ± 0.038	5.598ArgArg: 5.598 ± 0.086	3.556ArgSer: 3.556 ± 0.05	3.75ArgThr: 3.75 ± 0.052	5.645ArgVal: 5.645 ± 0.062	1.075ArgTrp: 1.075 ± 0.022	2.001ArgTyr: 2.001 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	7.364SerAla: 7.364 ± 0.088	0.422SerCys: 0.422 ± 0.014	3.239SerAsp: 3.239 ± 0.047	2.607SerGlu: 2.607 ± 0.039	2.019SerPhe: 2.019 ± 0.038	5.576SerGly: 5.576 ± 0.085	1.308SerHis: 1.308 ± 0.027	3.182SerIle: 3.182 ± 0.047	1.591SerLys: 1.591 ± 0.032	5.772SerLeu: 5.772 ± 0.057	1.477SerMet: 1.477 ± 0.032	1.769SerAsn: 1.769 ± 0.039	2.983SerPro: 2.983 ± 0.046	1.788SerGln: 1.788 ± 0.033	3.71SerArg: 3.71 ± 0.046	3.683SerSer: 3.683 ± 0.073	3.657SerThr: 3.657 ± 0.069	4.532SerVal: 4.532 ± 0.058	0.692SerTrp: 0.692 ± 0.019	1.305SerTyr: 1.305 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	6.046ThrAla: 6.046 ± 0.078	0.419ThrCys: 0.419 ± 0.015	2.939ThrAsp: 2.939 ± 0.052	2.284ThrGlu: 2.284 ± 0.034	2.112ThrPhe: 2.112 ± 0.035	5.01ThrGly: 5.01 ± 0.089	1.527ThrHis: 1.527 ± 0.031	3.055ThrIle: 3.055 ± 0.053	1.111ThrLys: 1.111 ± 0.025	6.844ThrLeu: 6.844 ± 0.083	1.198ThrMet: 1.198 ± 0.025	1.386ThrAsn: 1.386 ± 0.035	3.697ThrPro: 3.697 ± 0.049	2.057ThrGln: 2.057 ± 0.036	3.905ThrArg: 3.905 ± 0.048	3.42ThrSer: 3.42 ± 0.06	3.375ThrThr: 3.375 ± 0.084	4.51ThrVal: 4.51 ± 0.058	0.688ThrTrp: 0.688 ± 0.019	1.354ThrTyr: 1.354 ± 0.029	0.001ThrXaa: 0.001 ± 0.001
Val	9.564ValAla: 9.564 ± 0.089	0.779ValCys: 0.779 ± 0.022	4.639ValAsp: 4.639 ± 0.057	4.221ValGlu: 4.221 ± 0.055	2.962ValPhe: 2.962 ± 0.042	5.724ValGly: 5.724 ± 0.066	1.632ValHis: 1.632 ± 0.038	3.845ValIle: 3.845 ± 0.049	2.152ValLys: 2.152 ± 0.039	8.102ValLeu: 8.102 ± 0.088	1.786ValMet: 1.786 ± 0.031	2.193ValAsn: 2.193 ± 0.039	3.959ValPro: 3.959 ± 0.052	2.262ValGln: 2.262 ± 0.037	5.296ValArg: 5.296 ± 0.053	4.989ValSer: 4.989 ± 0.052	4.518ValThr: 4.518 ± 0.06	6.494ValVal: 6.494 ± 0.068	0.965ValTrp: 0.965 ± 0.026	1.659ValTyr: 1.659 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.114TrpAla: 1.114 ± 0.025	0.132TrpCys: 0.132 ± 0.008	0.602TrpAsp: 0.602 ± 0.018	0.454TrpGlu: 0.454 ± 0.016	0.52TrpPhe: 0.52 ± 0.019	0.898TrpGly: 0.898 ± 0.025	0.383TrpHis: 0.383 ± 0.015	0.83TrpIle: 0.83 ± 0.023	0.362TrpLys: 0.362 ± 0.014	1.766TrpLeu: 1.766 ± 0.039	0.367TrpMet: 0.367 ± 0.013	0.447TrpAsn: 0.447 ± 0.017	0.677TrpPro: 0.677 ± 0.021	0.622TrpGln: 0.622 ± 0.018	1.233TrpArg: 1.233 ± 0.027	0.789TrpSer: 0.789 ± 0.022	0.758TrpThr: 0.758 ± 0.022	0.908TrpVal: 0.908 ± 0.024	0.198TrpTrp: 0.198 ± 0.011	0.315TrpTyr: 0.315 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.049TyrAla: 3.049 ± 0.046	0.237TyrCys: 0.237 ± 0.012	1.433TyrAsp: 1.433 ± 0.035	1.206TyrGlu: 1.206 ± 0.027	0.981TyrPhe: 0.981 ± 0.025	2.207TyrGly: 2.207 ± 0.038	0.475TyrHis: 0.475 ± 0.016	0.876TyrIle: 0.876 ± 0.023	0.569TyrLys: 0.569 ± 0.017	2.492TyrLeu: 2.492 ± 0.039	0.419TyrMet: 0.419 ± 0.015	0.625TyrAsn: 0.625 ± 0.021	1.215TyrPro: 1.215 ± 0.029	0.795TyrGln: 0.795 ± 0.021	1.862TyrArg: 1.862 ± 0.031	1.304TyrSer: 1.304 ± 0.027	1.353TyrThr: 1.353 ± 0.031	1.895TyrVal: 1.895 ± 0.032	0.348TyrTrp: 0.348 ± 0.015	0.629TyrTyr: 0.629 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.001XaaMet: 0.001 ± 0.001	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.001

Statistics based on 5622 proteins (1887409 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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