Amino acid dipepetide frequency for Hubei picorna-like virus 47

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.494AlaAla: 4.494 ± 0.0
1.605AlaCys: 1.605 ± 0.0
2.568AlaAsp: 2.568 ± 0.0
4.494AlaGlu: 4.494 ± 0.0
4.494AlaPhe: 4.494 ± 0.0
5.457AlaGly: 5.457 ± 0.0
1.926AlaHis: 1.926 ± 0.0
3.21AlaIle: 3.21 ± 0.0
4.494AlaLys: 4.494 ± 0.0
6.421AlaLeu: 6.421 ± 0.0
2.247AlaMet: 2.247 ± 0.0
4.494AlaAsn: 4.494 ± 0.0
2.568AlaPro: 2.568 ± 0.0
5.136AlaGln: 5.136 ± 0.0
2.889AlaArg: 2.889 ± 0.0
4.815AlaSer: 4.815 ± 0.0
5.778AlaThr: 5.778 ± 0.0
4.173AlaVal: 4.173 ± 0.0
0.642AlaTrp: 0.642 ± 0.0
2.247AlaTyr: 2.247 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.284CysAla: 1.284 ± 0.0
1.284CysCys: 1.284 ± 0.0
0.963CysAsp: 0.963 ± 0.0
1.284CysGlu: 1.284 ± 0.0
1.284CysPhe: 1.284 ± 0.0
1.926CysGly: 1.926 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.284CysIle: 1.284 ± 0.0
1.284CysLys: 1.284 ± 0.0
1.284CysLeu: 1.284 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.642CysAsn: 0.642 ± 0.0
1.284CysPro: 1.284 ± 0.0
0.642CysGln: 0.642 ± 0.0
1.926CysArg: 1.926 ± 0.0
0.963CysSer: 0.963 ± 0.0
0.321CysThr: 0.321 ± 0.0
2.568CysVal: 2.568 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.321CysTyr: 0.321 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.173AspAla: 4.173 ± 0.0
0.321AspCys: 0.321 ± 0.0
4.173AspAsp: 4.173 ± 0.0
4.494AspGlu: 4.494 ± 0.0
4.494AspPhe: 4.494 ± 0.0
2.889AspGly: 2.889 ± 0.0
0.963AspHis: 0.963 ± 0.0
1.605AspIle: 1.605 ± 0.0
4.815AspLys: 4.815 ± 0.0
3.21AspLeu: 3.21 ± 0.0
2.247AspMet: 2.247 ± 0.0
2.247AspAsn: 2.247 ± 0.0
2.568AspPro: 2.568 ± 0.0
0.963AspGln: 0.963 ± 0.0
2.247AspArg: 2.247 ± 0.0
1.926AspSer: 1.926 ± 0.0
2.889AspThr: 2.889 ± 0.0
5.457AspVal: 5.457 ± 0.0
1.605AspTrp: 1.605 ± 0.0
1.926AspTyr: 1.926 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.421GluAla: 6.421 ± 0.0
1.926GluCys: 1.926 ± 0.0
4.173GluAsp: 4.173 ± 0.0
7.384GluGlu: 7.384 ± 0.0
2.247GluPhe: 2.247 ± 0.0
6.742GluGly: 6.742 ± 0.0
1.605GluHis: 1.605 ± 0.0
2.568GluIle: 2.568 ± 0.0
2.247GluLys: 2.247 ± 0.0
5.457GluLeu: 5.457 ± 0.0
2.247GluMet: 2.247 ± 0.0
3.21GluAsn: 3.21 ± 0.0
5.136GluPro: 5.136 ± 0.0
3.852GluGln: 3.852 ± 0.0
4.494GluArg: 4.494 ± 0.0
3.21GluSer: 3.21 ± 0.0
2.247GluThr: 2.247 ± 0.0
5.778GluVal: 5.778 ± 0.0
2.568GluTrp: 2.568 ± 0.0
2.889GluTyr: 2.889 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.926PheAla: 1.926 ± 0.0
0.642PheCys: 0.642 ± 0.0
3.21PheAsp: 3.21 ± 0.0
3.531PheGlu: 3.531 ± 0.0
1.605PhePhe: 1.605 ± 0.0
3.21PheGly: 3.21 ± 0.0
1.284PheHis: 1.284 ± 0.0
1.926PheIle: 1.926 ± 0.0
3.531PheLys: 3.531 ± 0.0
1.926PheLeu: 1.926 ± 0.0
2.247PheMet: 2.247 ± 0.0
2.568PheAsn: 2.568 ± 0.0
3.531PhePro: 3.531 ± 0.0
1.605PheGln: 1.605 ± 0.0
2.568PheArg: 2.568 ± 0.0
2.889PheSer: 2.889 ± 0.0
2.247PheThr: 2.247 ± 0.0
4.494PheVal: 4.494 ± 0.0
1.284PheTrp: 1.284 ± 0.0
2.247PheTyr: 2.247 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.531GlyAla: 3.531 ± 0.0
0.963GlyCys: 0.963 ± 0.0
4.494GlyAsp: 4.494 ± 0.0
5.457GlyGlu: 5.457 ± 0.0
2.247GlyPhe: 2.247 ± 0.0
2.568GlyGly: 2.568 ± 0.0
0.642GlyHis: 0.642 ± 0.0
1.605GlyIle: 1.605 ± 0.0
6.421GlyLys: 6.421 ± 0.0
5.457GlyLeu: 5.457 ± 0.0
3.21GlyMet: 3.21 ± 0.0
3.21GlyAsn: 3.21 ± 0.0
2.568GlyPro: 2.568 ± 0.0
1.605GlyGln: 1.605 ± 0.0
3.531GlyArg: 3.531 ± 0.0
2.568GlySer: 2.568 ± 0.0
4.173GlyThr: 4.173 ± 0.0
3.852GlyVal: 3.852 ± 0.0
1.926GlyTrp: 1.926 ± 0.0
3.531GlyTyr: 3.531 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.284HisAla: 1.284 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.963HisAsp: 0.963 ± 0.0
1.284HisGlu: 1.284 ± 0.0
0.642HisPhe: 0.642 ± 0.0
2.568HisGly: 2.568 ± 0.0
1.284HisHis: 1.284 ± 0.0
0.642HisIle: 0.642 ± 0.0
1.605HisLys: 1.605 ± 0.0
2.247HisLeu: 2.247 ± 0.0
1.605HisMet: 1.605 ± 0.0
1.284HisAsn: 1.284 ± 0.0
0.642HisPro: 0.642 ± 0.0
0.321HisGln: 0.321 ± 0.0
1.284HisArg: 1.284 ± 0.0
1.926HisSer: 1.926 ± 0.0
0.642HisThr: 0.642 ± 0.0
1.284HisVal: 1.284 ± 0.0
0.642HisTrp: 0.642 ± 0.0
0.963HisTyr: 0.963 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.531IleAla: 3.531 ± 0.0
0.0IleCys: 0.0 ± 0.0
3.21IleAsp: 3.21 ± 0.0
2.247IleGlu: 2.247 ± 0.0
1.284IlePhe: 1.284 ± 0.0
1.926IleGly: 1.926 ± 0.0
1.605IleHis: 1.605 ± 0.0
2.889IleIle: 2.889 ± 0.0
2.568IleLys: 2.568 ± 0.0
2.568IleLeu: 2.568 ± 0.0
1.926IleMet: 1.926 ± 0.0
1.605IleAsn: 1.605 ± 0.0
3.852IlePro: 3.852 ± 0.0
2.247IleGln: 2.247 ± 0.0
2.889IleArg: 2.889 ± 0.0
2.889IleSer: 2.889 ± 0.0
2.889IleThr: 2.889 ± 0.0
2.247IleVal: 2.247 ± 0.0
0.642IleTrp: 0.642 ± 0.0
2.889IleTyr: 2.889 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
6.1LysAla: 6.1 ± 0.0
0.642LysCys: 0.642 ± 0.0
5.136LysAsp: 5.136 ± 0.0
3.852LysGlu: 3.852 ± 0.0
3.852LysPhe: 3.852 ± 0.0
3.21LysGly: 3.21 ± 0.0
1.605LysHis: 1.605 ± 0.0
4.173LysIle: 4.173 ± 0.0
2.889LysLys: 2.889 ± 0.0
5.457LysLeu: 5.457 ± 0.0
0.963LysMet: 0.963 ± 0.0
3.852LysAsn: 3.852 ± 0.0
2.568LysPro: 2.568 ± 0.0
1.605LysGln: 1.605 ± 0.0
1.926LysArg: 1.926 ± 0.0
2.247LysSer: 2.247 ± 0.0
4.815LysThr: 4.815 ± 0.0
3.21LysVal: 3.21 ± 0.0
0.963LysTrp: 0.963 ± 0.0
2.889LysTyr: 2.889 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.815LeuAla: 4.815 ± 0.0
1.926LeuCys: 1.926 ± 0.0
3.531LeuAsp: 3.531 ± 0.0
7.705LeuGlu: 7.705 ± 0.0
2.568LeuPhe: 2.568 ± 0.0
4.815LeuGly: 4.815 ± 0.0
1.605LeuHis: 1.605 ± 0.0
1.926LeuIle: 1.926 ± 0.0
5.136LeuLys: 5.136 ± 0.0
4.815LeuLeu: 4.815 ± 0.0
1.926LeuMet: 1.926 ± 0.0
2.889LeuAsn: 2.889 ± 0.0
2.889LeuPro: 2.889 ± 0.0
2.247LeuGln: 2.247 ± 0.0
6.1LeuArg: 6.1 ± 0.0
3.852LeuSer: 3.852 ± 0.0
4.173LeuThr: 4.173 ± 0.0
3.21LeuVal: 3.21 ± 0.0
1.926LeuTrp: 1.926 ± 0.0
3.21LeuTyr: 3.21 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.926MetAla: 1.926 ± 0.0
1.605MetCys: 1.605 ± 0.0
2.247MetAsp: 2.247 ± 0.0
3.21MetGlu: 3.21 ± 0.0
0.642MetPhe: 0.642 ± 0.0
0.642MetGly: 0.642 ± 0.0
0.963MetHis: 0.963 ± 0.0
0.963MetIle: 0.963 ± 0.0
1.926MetLys: 1.926 ± 0.0
4.173MetLeu: 4.173 ± 0.0
2.568MetMet: 2.568 ± 0.0
1.605MetAsn: 1.605 ± 0.0
1.605MetPro: 1.605 ± 0.0
1.284MetGln: 1.284 ± 0.0
2.889MetArg: 2.889 ± 0.0
3.21MetSer: 3.21 ± 0.0
1.605MetThr: 1.605 ± 0.0
0.642MetVal: 0.642 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.642MetTyr: 0.642 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.494AsnAla: 4.494 ± 0.0
1.605AsnCys: 1.605 ± 0.0
2.247AsnAsp: 2.247 ± 0.0
3.21AsnGlu: 3.21 ± 0.0
2.568AsnPhe: 2.568 ± 0.0
2.247AsnGly: 2.247 ± 0.0
1.605AsnHis: 1.605 ± 0.0
3.531AsnIle: 3.531 ± 0.0
2.568AsnLys: 2.568 ± 0.0
4.494AsnLeu: 4.494 ± 0.0
1.284AsnMet: 1.284 ± 0.0
1.605AsnAsn: 1.605 ± 0.0
1.284AsnPro: 1.284 ± 0.0
2.247AsnGln: 2.247 ± 0.0
2.247AsnArg: 2.247 ± 0.0
2.568AsnSer: 2.568 ± 0.0
2.247AsnThr: 2.247 ± 0.0
3.21AsnVal: 3.21 ± 0.0
1.284AsnTrp: 1.284 ± 0.0
0.963AsnTyr: 0.963 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.173ProAla: 4.173 ± 0.0
0.963ProCys: 0.963 ± 0.0
2.889ProAsp: 2.889 ± 0.0
2.568ProGlu: 2.568 ± 0.0
2.568ProPhe: 2.568 ± 0.0
2.889ProGly: 2.889 ± 0.0
1.284ProHis: 1.284 ± 0.0
2.889ProIle: 2.889 ± 0.0
2.889ProLys: 2.889 ± 0.0
2.889ProLeu: 2.889 ± 0.0
0.963ProMet: 0.963 ± 0.0
2.889ProAsn: 2.889 ± 0.0
1.926ProPro: 1.926 ± 0.0
0.642ProGln: 0.642 ± 0.0
3.21ProArg: 3.21 ± 0.0
3.21ProSer: 3.21 ± 0.0
1.926ProThr: 1.926 ± 0.0
3.531ProVal: 3.531 ± 0.0
0.642ProTrp: 0.642 ± 0.0
2.889ProTyr: 2.889 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.531GlnAla: 3.531 ± 0.0
0.642GlnCys: 0.642 ± 0.0
1.926GlnAsp: 1.926 ± 0.0
3.531GlnGlu: 3.531 ± 0.0
0.963GlnPhe: 0.963 ± 0.0
1.605GlnGly: 1.605 ± 0.0
0.642GlnHis: 0.642 ± 0.0
1.605GlnIle: 1.605 ± 0.0
1.926GlnLys: 1.926 ± 0.0
1.605GlnLeu: 1.605 ± 0.0
0.963GlnMet: 0.963 ± 0.0
0.963GlnAsn: 0.963 ± 0.0
1.284GlnPro: 1.284 ± 0.0
1.605GlnGln: 1.605 ± 0.0
2.247GlnArg: 2.247 ± 0.0
0.963GlnSer: 0.963 ± 0.0
3.21GlnThr: 3.21 ± 0.0
1.926GlnVal: 1.926 ± 0.0
0.963GlnTrp: 0.963 ± 0.0
1.926GlnTyr: 1.926 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.531ArgAla: 3.531 ± 0.0
1.605ArgCys: 1.605 ± 0.0
3.21ArgAsp: 3.21 ± 0.0
6.1ArgGlu: 6.1 ± 0.0
1.926ArgPhe: 1.926 ± 0.0
2.568ArgGly: 2.568 ± 0.0
0.642ArgHis: 0.642 ± 0.0
2.568ArgIle: 2.568 ± 0.0
4.815ArgLys: 4.815 ± 0.0
3.531ArgLeu: 3.531 ± 0.0
1.605ArgMet: 1.605 ± 0.0
2.247ArgAsn: 2.247 ± 0.0
1.926ArgPro: 1.926 ± 0.0
1.284ArgGln: 1.284 ± 0.0
5.136ArgArg: 5.136 ± 0.0
1.926ArgSer: 1.926 ± 0.0
4.494ArgThr: 4.494 ± 0.0
4.815ArgVal: 4.815 ± 0.0
0.642ArgTrp: 0.642 ± 0.0
1.284ArgTyr: 1.284 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.852SerAla: 3.852 ± 0.0
0.321SerCys: 0.321 ± 0.0
1.926SerAsp: 1.926 ± 0.0
3.531SerGlu: 3.531 ± 0.0
3.21SerPhe: 3.21 ± 0.0
5.457SerGly: 5.457 ± 0.0
2.247SerHis: 2.247 ± 0.0
3.531SerIle: 3.531 ± 0.0
3.531SerLys: 3.531 ± 0.0
3.531SerLeu: 3.531 ± 0.0
3.21SerMet: 3.21 ± 0.0
3.21SerAsn: 3.21 ± 0.0
1.926SerPro: 1.926 ± 0.0
0.642SerGln: 0.642 ± 0.0
1.926SerArg: 1.926 ± 0.0
2.889SerSer: 2.889 ± 0.0
1.605SerThr: 1.605 ± 0.0
4.815SerVal: 4.815 ± 0.0
1.605SerTrp: 1.605 ± 0.0
1.926SerTyr: 1.926 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.136ThrAla: 5.136 ± 0.0
1.284ThrCys: 1.284 ± 0.0
1.926ThrAsp: 1.926 ± 0.0
4.494ThrGlu: 4.494 ± 0.0
4.173ThrPhe: 4.173 ± 0.0
3.21ThrGly: 3.21 ± 0.0
0.642ThrHis: 0.642 ± 0.0
3.531ThrIle: 3.531 ± 0.0
2.889ThrLys: 2.889 ± 0.0
4.494ThrLeu: 4.494 ± 0.0
0.963ThrMet: 0.963 ± 0.0
2.247ThrAsn: 2.247 ± 0.0
3.531ThrPro: 3.531 ± 0.0
1.926ThrGln: 1.926 ± 0.0
2.247ThrArg: 2.247 ± 0.0
4.494ThrSer: 4.494 ± 0.0
1.605ThrThr: 1.605 ± 0.0
3.852ThrVal: 3.852 ± 0.0
0.642ThrTrp: 0.642 ± 0.0
3.21ThrTyr: 3.21 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
7.063ValAla: 7.063 ± 0.0
1.605ValCys: 1.605 ± 0.0
2.247ValAsp: 2.247 ± 0.0
3.531ValGlu: 3.531 ± 0.0
3.531ValPhe: 3.531 ± 0.0
6.421ValGly: 6.421 ± 0.0
1.605ValHis: 1.605 ± 0.0
3.21ValIle: 3.21 ± 0.0
3.852ValLys: 3.852 ± 0.0
3.531ValLeu: 3.531 ± 0.0
1.605ValMet: 1.605 ± 0.0
4.173ValAsn: 4.173 ± 0.0
4.494ValPro: 4.494 ± 0.0
1.605ValGln: 1.605 ± 0.0
3.531ValArg: 3.531 ± 0.0
3.852ValSer: 3.852 ± 0.0
5.136ValThr: 5.136 ± 0.0
4.173ValVal: 4.173 ± 0.0
1.605ValTrp: 1.605 ± 0.0
1.284ValTyr: 1.284 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.963TrpAla: 0.963 ± 0.0
1.284TrpCys: 1.284 ± 0.0
1.284TrpAsp: 1.284 ± 0.0
1.284TrpGlu: 1.284 ± 0.0
1.926TrpPhe: 1.926 ± 0.0
0.642TrpGly: 0.642 ± 0.0
0.321TrpHis: 0.321 ± 0.0
0.321TrpIle: 0.321 ± 0.0
0.963TrpLys: 0.963 ± 0.0
1.605TrpLeu: 1.605 ± 0.0
1.284TrpMet: 1.284 ± 0.0
0.963TrpAsn: 0.963 ± 0.0
0.321TrpPro: 0.321 ± 0.0
0.963TrpGln: 0.963 ± 0.0
1.284TrpArg: 1.284 ± 0.0
1.926TrpSer: 1.926 ± 0.0
1.284TrpThr: 1.284 ± 0.0
1.605TrpVal: 1.605 ± 0.0
0.963TrpTrp: 0.963 ± 0.0
0.321TrpTyr: 0.321 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.247TyrAla: 2.247 ± 0.0
0.321TyrCys: 0.321 ± 0.0
2.889TyrAsp: 2.889 ± 0.0
3.21TyrGlu: 3.21 ± 0.0
2.247TyrPhe: 2.247 ± 0.0
2.568TyrGly: 2.568 ± 0.0
0.642TyrHis: 0.642 ± 0.0
1.926TyrIle: 1.926 ± 0.0
1.605TyrLys: 1.605 ± 0.0
2.568TyrLeu: 2.568 ± 0.0
0.963TyrMet: 0.963 ± 0.0
1.605TyrAsn: 1.605 ± 0.0
1.926TyrPro: 1.926 ± 0.0
1.605TyrGln: 1.605 ± 0.0
1.284TyrArg: 1.284 ± 0.0
2.568TyrSer: 2.568 ± 0.0
3.21TyrThr: 3.21 ± 0.0
3.21TyrVal: 3.21 ± 0.0
0.963TyrTrp: 0.963 ± 0.0
1.284TyrTyr: 1.284 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3116 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski