Amino acid dipepetide frequency for Klebsiella phage ST11-VIM1phi8.1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.766AlaAla: 11.766 ± 2.018
0.917AlaCys: 0.917 ± 0.306
5.883AlaAsp: 5.883 ± 0.761
8.328AlaGlu: 8.328 ± 0.947
2.216AlaPhe: 2.216 ± 0.385
7.334AlaGly: 7.334 ± 0.816
1.146AlaHis: 1.146 ± 0.312
5.119AlaIle: 5.119 ± 0.694
7.334AlaLys: 7.334 ± 0.925
9.015AlaLeu: 9.015 ± 0.833
3.362AlaMet: 3.362 ± 0.463
4.66AlaAsn: 4.66 ± 0.624
2.368AlaPro: 2.368 ± 0.401
4.966AlaGln: 4.966 ± 0.954
5.883AlaArg: 5.883 ± 0.851
6.57AlaSer: 6.57 ± 0.789
6.57AlaThr: 6.57 ± 0.834
4.813AlaVal: 4.813 ± 0.58
2.139AlaTrp: 2.139 ± 0.396
2.598AlaTyr: 2.598 ± 0.455
0.0AlaXaa: 0.0 ± 0.0
Cys
1.375CysAla: 1.375 ± 0.395
0.382CysCys: 0.382 ± 0.215
0.993CysAsp: 0.993 ± 0.26
0.84CysGlu: 0.84 ± 0.327
0.229CysPhe: 0.229 ± 0.142
0.688CysGly: 0.688 ± 0.263
0.382CysHis: 0.382 ± 0.203
0.535CysIle: 0.535 ± 0.229
0.535CysLys: 0.535 ± 0.187
1.222CysLeu: 1.222 ± 0.349
0.458CysMet: 0.458 ± 0.176
0.382CysAsn: 0.382 ± 0.159
0.688CysPro: 0.688 ± 0.229
0.535CysGln: 0.535 ± 0.213
0.993CysArg: 0.993 ± 0.269
0.993CysSer: 0.993 ± 0.267
0.611CysThr: 0.611 ± 0.256
0.458CysVal: 0.458 ± 0.191
0.458CysTrp: 0.458 ± 0.199
0.382CysTyr: 0.382 ± 0.179
0.0CysXaa: 0.0 ± 0.0
Asp
5.959AspAla: 5.959 ± 0.785
0.917AspCys: 0.917 ± 0.295
4.126AspAsp: 4.126 ± 0.588
3.896AspGlu: 3.896 ± 0.602
2.445AspPhe: 2.445 ± 0.459
4.355AspGly: 4.355 ± 0.673
0.688AspHis: 0.688 ± 0.217
2.368AspIle: 2.368 ± 0.445
3.132AspLys: 3.132 ± 0.667
3.667AspLeu: 3.667 ± 0.482
1.91AspMet: 1.91 ± 0.293
2.827AspAsn: 2.827 ± 0.575
1.986AspPro: 1.986 ± 0.431
2.368AspGln: 2.368 ± 0.385
2.75AspArg: 2.75 ± 0.492
2.75AspSer: 2.75 ± 0.571
3.438AspThr: 3.438 ± 0.572
3.591AspVal: 3.591 ± 0.721
1.986AspTrp: 1.986 ± 0.431
2.98AspTyr: 2.98 ± 0.509
0.0AspXaa: 0.0 ± 0.0
Glu
6.647GluAla: 6.647 ± 0.823
0.917GluCys: 0.917 ± 0.279
2.521GluAsp: 2.521 ± 0.456
3.973GluGlu: 3.973 ± 0.742
2.98GluPhe: 2.98 ± 0.498
3.896GluGly: 3.896 ± 0.641
0.917GluHis: 0.917 ± 0.31
3.591GluIle: 3.591 ± 0.587
4.966GluLys: 4.966 ± 0.626
6.341GluLeu: 6.341 ± 0.701
2.292GluMet: 2.292 ± 0.493
2.827GluAsn: 2.827 ± 0.493
2.063GluPro: 2.063 ± 0.516
3.591GluGln: 3.591 ± 0.461
4.737GluArg: 4.737 ± 0.604
3.667GluSer: 3.667 ± 0.622
2.292GluThr: 2.292 ± 0.402
4.278GluVal: 4.278 ± 0.498
1.07GluTrp: 1.07 ± 0.237
2.827GluTyr: 2.827 ± 0.487
0.0GluXaa: 0.0 ± 0.0
Phe
3.438PheAla: 3.438 ± 0.493
0.153PheCys: 0.153 ± 0.105
2.598PheAsp: 2.598 ± 0.455
1.91PheGlu: 1.91 ± 0.404
1.299PhePhe: 1.299 ± 0.463
2.292PheGly: 2.292 ± 0.393
0.84PheHis: 0.84 ± 0.232
1.986PheIle: 1.986 ± 0.409
1.222PheLys: 1.222 ± 0.342
1.91PheLeu: 1.91 ± 0.339
0.917PheMet: 0.917 ± 0.276
1.222PheAsn: 1.222 ± 0.334
0.917PhePro: 0.917 ± 0.258
0.84PheGln: 0.84 ± 0.256
2.368PheArg: 2.368 ± 0.58
2.445PheSer: 2.445 ± 0.406
2.521PheThr: 2.521 ± 0.426
2.139PheVal: 2.139 ± 0.375
0.611PheTrp: 0.611 ± 0.234
1.681PheTyr: 1.681 ± 0.381
0.0PheXaa: 0.0 ± 0.0
Gly
6.418GlyAla: 6.418 ± 0.728
1.757GlyCys: 1.757 ± 0.39
4.813GlyAsp: 4.813 ± 0.638
4.66GlyGlu: 4.66 ± 0.545
2.521GlyPhe: 2.521 ± 0.422
4.584GlyGly: 4.584 ± 0.607
0.535GlyHis: 0.535 ± 0.197
5.348GlyIle: 5.348 ± 0.557
5.272GlyLys: 5.272 ± 0.596
5.195GlyLeu: 5.195 ± 0.658
1.757GlyMet: 1.757 ± 0.288
2.445GlyAsn: 2.445 ± 0.412
1.604GlyPro: 1.604 ± 0.277
2.98GlyGln: 2.98 ± 0.568
3.896GlyArg: 3.896 ± 0.485
2.75GlySer: 2.75 ± 0.526
2.98GlyThr: 2.98 ± 0.542
4.431GlyVal: 4.431 ± 0.453
0.764GlyTrp: 0.764 ± 0.224
2.903GlyTyr: 2.903 ± 0.478
0.0GlyXaa: 0.0 ± 0.0
His
0.993HisAla: 0.993 ± 0.263
0.382HisCys: 0.382 ± 0.16
0.917HisAsp: 0.917 ± 0.257
0.993HisGlu: 0.993 ± 0.259
0.917HisPhe: 0.917 ± 0.279
1.222HisGly: 1.222 ± 0.337
0.458HisHis: 0.458 ± 0.175
0.993HisIle: 0.993 ± 0.324
0.84HisLys: 0.84 ± 0.218
1.681HisLeu: 1.681 ± 0.451
0.153HisMet: 0.153 ± 0.118
0.688HisAsn: 0.688 ± 0.278
0.993HisPro: 0.993 ± 0.318
0.535HisGln: 0.535 ± 0.209
1.146HisArg: 1.146 ± 0.221
0.84HisSer: 0.84 ± 0.215
0.917HisThr: 0.917 ± 0.246
1.375HisVal: 1.375 ± 0.293
0.611HisTrp: 0.611 ± 0.168
0.535HisTyr: 0.535 ± 0.191
0.0HisXaa: 0.0 ± 0.0
Ile
6.112IleAla: 6.112 ± 0.695
0.84IleCys: 0.84 ± 0.264
3.285IleAsp: 3.285 ± 0.458
3.514IleGlu: 3.514 ± 0.631
1.834IlePhe: 1.834 ± 0.419
4.049IleGly: 4.049 ± 0.582
1.222IleHis: 1.222 ± 0.28
2.674IleIle: 2.674 ± 0.364
3.285IleLys: 3.285 ± 0.406
3.056IleLeu: 3.056 ± 0.543
0.611IleMet: 0.611 ± 0.191
2.216IleAsn: 2.216 ± 0.497
1.757IlePro: 1.757 ± 0.408
1.375IleGln: 1.375 ± 0.266
2.674IleArg: 2.674 ± 0.488
4.89IleSer: 4.89 ± 0.522
4.813IleThr: 4.813 ± 0.479
3.132IleVal: 3.132 ± 0.404
0.917IleTrp: 0.917 ± 0.271
2.139IleTyr: 2.139 ± 0.449
0.0IleXaa: 0.0 ± 0.0
Lys
6.8LysAla: 6.8 ± 0.647
1.07LysCys: 1.07 ± 0.345
3.056LysAsp: 3.056 ± 0.648
3.591LysGlu: 3.591 ± 0.472
1.757LysPhe: 1.757 ± 0.311
3.209LysGly: 3.209 ± 0.444
1.375LysHis: 1.375 ± 0.374
2.827LysIle: 2.827 ± 0.456
3.744LysLys: 3.744 ± 0.583
4.278LysLeu: 4.278 ± 0.586
1.757LysMet: 1.757 ± 0.424
1.986LysAsn: 1.986 ± 0.399
2.827LysPro: 2.827 ± 0.503
2.98LysGln: 2.98 ± 0.39
4.508LysArg: 4.508 ± 0.761
4.049LysSer: 4.049 ± 0.604
3.973LysThr: 3.973 ± 0.652
3.667LysVal: 3.667 ± 0.463
0.764LysTrp: 0.764 ± 0.272
1.146LysTyr: 1.146 ± 0.294
0.0LysXaa: 0.0 ± 0.0
Leu
9.321LeuAla: 9.321 ± 0.958
0.993LeuCys: 0.993 ± 0.285
3.514LeuAsp: 3.514 ± 0.471
4.584LeuGlu: 4.584 ± 0.746
2.216LeuPhe: 2.216 ± 0.366
4.737LeuGly: 4.737 ± 0.615
1.452LeuHis: 1.452 ± 0.318
4.966LeuIle: 4.966 ± 0.564
4.584LeuLys: 4.584 ± 0.598
5.654LeuLeu: 5.654 ± 0.764
1.91LeuMet: 1.91 ± 0.339
3.896LeuAsn: 3.896 ± 0.565
3.438LeuPro: 3.438 ± 0.706
3.056LeuGln: 3.056 ± 0.437
5.73LeuArg: 5.73 ± 0.762
5.119LeuSer: 5.119 ± 0.587
4.355LeuThr: 4.355 ± 0.552
4.278LeuVal: 4.278 ± 0.739
0.764LeuTrp: 0.764 ± 0.291
2.445LeuTyr: 2.445 ± 0.387
0.0LeuXaa: 0.0 ± 0.0
Met
2.368MetAla: 2.368 ± 0.435
0.0MetCys: 0.0 ± 0.0
1.146MetAsp: 1.146 ± 0.33
1.222MetGlu: 1.222 ± 0.309
0.611MetPhe: 0.611 ± 0.196
1.375MetGly: 1.375 ± 0.373
0.458MetHis: 0.458 ± 0.222
0.993MetIle: 0.993 ± 0.304
2.139MetLys: 2.139 ± 0.52
0.993MetLeu: 0.993 ± 0.276
0.611MetMet: 0.611 ± 0.312
1.375MetAsn: 1.375 ± 0.291
1.681MetPro: 1.681 ± 0.46
1.07MetGln: 1.07 ± 0.312
1.757MetArg: 1.757 ± 0.314
2.445MetSer: 2.445 ± 0.331
2.521MetThr: 2.521 ± 0.562
2.139MetVal: 2.139 ± 0.399
0.535MetTrp: 0.535 ± 0.185
0.688MetTyr: 0.688 ± 0.195
0.0MetXaa: 0.0 ± 0.0
Asn
4.66AsnAla: 4.66 ± 0.799
0.611AsnCys: 0.611 ± 0.236
2.368AsnAsp: 2.368 ± 0.467
2.445AsnGlu: 2.445 ± 0.462
0.993AsnPhe: 0.993 ± 0.239
4.202AsnGly: 4.202 ± 0.615
0.764AsnHis: 0.764 ± 0.279
2.75AsnIle: 2.75 ± 0.449
2.292AsnLys: 2.292 ± 0.383
2.75AsnLeu: 2.75 ± 0.374
1.146AsnMet: 1.146 ± 0.353
2.598AsnAsn: 2.598 ± 0.409
2.216AsnPro: 2.216 ± 0.409
2.216AsnGln: 2.216 ± 0.563
2.521AsnArg: 2.521 ± 0.445
3.209AsnSer: 3.209 ± 0.516
1.834AsnThr: 1.834 ± 0.366
2.827AsnVal: 2.827 ± 0.471
0.458AsnTrp: 0.458 ± 0.173
1.375AsnTyr: 1.375 ± 0.276
0.0AsnXaa: 0.0 ± 0.0
Pro
3.82ProAla: 3.82 ± 0.622
0.306ProCys: 0.306 ± 0.149
2.827ProAsp: 2.827 ± 0.396
3.209ProGlu: 3.209 ± 0.458
0.84ProPhe: 0.84 ± 0.242
2.598ProGly: 2.598 ± 0.554
0.84ProHis: 0.84 ± 0.258
1.528ProIle: 1.528 ± 0.4
1.528ProLys: 1.528 ± 0.322
3.438ProLeu: 3.438 ± 0.568
0.84ProMet: 0.84 ± 0.243
1.375ProAsn: 1.375 ± 0.37
1.604ProPro: 1.604 ± 0.456
1.681ProGln: 1.681 ± 0.357
1.681ProArg: 1.681 ± 0.38
2.063ProSer: 2.063 ± 0.412
2.063ProThr: 2.063 ± 0.462
3.82ProVal: 3.82 ± 0.493
0.382ProTrp: 0.382 ± 0.192
0.688ProTyr: 0.688 ± 0.261
0.0ProXaa: 0.0 ± 0.0
Gln
5.042GlnAla: 5.042 ± 1.141
0.688GlnCys: 0.688 ± 0.2
1.375GlnAsp: 1.375 ± 0.25
2.139GlnGlu: 2.139 ± 0.422
1.681GlnPhe: 1.681 ± 0.369
2.674GlnGly: 2.674 ± 0.721
0.688GlnHis: 0.688 ± 0.237
2.063GlnIle: 2.063 ± 0.413
2.827GlnLys: 2.827 ± 0.486
3.591GlnLeu: 3.591 ± 0.532
1.452GlnMet: 1.452 ± 0.308
1.146GlnAsn: 1.146 ± 0.243
1.222GlnPro: 1.222 ± 0.367
3.209GlnGln: 3.209 ± 0.884
2.521GlnArg: 2.521 ± 0.429
3.056GlnSer: 3.056 ± 0.596
2.598GlnThr: 2.598 ± 0.551
3.591GlnVal: 3.591 ± 0.649
0.611GlnTrp: 0.611 ± 0.172
1.452GlnTyr: 1.452 ± 0.537
0.0GlnXaa: 0.0 ± 0.0
Arg
5.119ArgAla: 5.119 ± 0.636
0.688ArgCys: 0.688 ± 0.239
4.278ArgAsp: 4.278 ± 0.492
5.424ArgGlu: 5.424 ± 0.943
1.528ArgPhe: 1.528 ± 0.299
4.049ArgGly: 4.049 ± 0.551
1.299ArgHis: 1.299 ± 0.322
3.285ArgIle: 3.285 ± 0.397
3.973ArgLys: 3.973 ± 0.662
4.966ArgLeu: 4.966 ± 0.68
1.452ArgMet: 1.452 ± 0.388
2.75ArgAsn: 2.75 ± 0.359
2.139ArgPro: 2.139 ± 0.438
2.827ArgGln: 2.827 ± 0.474
4.355ArgArg: 4.355 ± 0.727
3.896ArgSer: 3.896 ± 0.514
2.674ArgThr: 2.674 ± 0.49
3.896ArgVal: 3.896 ± 0.565
1.834ArgTrp: 1.834 ± 0.393
1.91ArgTyr: 1.91 ± 0.419
0.0ArgXaa: 0.0 ± 0.0
Ser
6.418SerAla: 6.418 ± 0.598
0.611SerCys: 0.611 ± 0.247
3.896SerAsp: 3.896 ± 0.564
4.737SerGlu: 4.737 ± 0.58
2.75SerPhe: 2.75 ± 0.395
4.508SerGly: 4.508 ± 0.596
0.917SerHis: 0.917 ± 0.333
3.285SerIle: 3.285 ± 0.407
3.285SerLys: 3.285 ± 0.586
5.348SerLeu: 5.348 ± 0.689
1.757SerMet: 1.757 ± 0.418
3.132SerAsn: 3.132 ± 0.594
2.139SerPro: 2.139 ± 0.432
2.445SerGln: 2.445 ± 0.546
3.973SerArg: 3.973 ± 0.41
3.82SerSer: 3.82 ± 0.664
3.744SerThr: 3.744 ± 0.559
4.431SerVal: 4.431 ± 0.727
0.993SerTrp: 0.993 ± 0.242
1.299SerTyr: 1.299 ± 0.319
0.0SerXaa: 0.0 ± 0.0
Thr
6.494ThrAla: 6.494 ± 0.757
0.382ThrCys: 0.382 ± 0.228
3.209ThrAsp: 3.209 ± 0.508
4.202ThrGlu: 4.202 ± 0.428
1.986ThrPhe: 1.986 ± 0.346
5.424ThrGly: 5.424 ± 0.608
0.993ThrHis: 0.993 ± 0.31
3.514ThrIle: 3.514 ± 0.648
2.063ThrLys: 2.063 ± 0.375
4.966ThrLeu: 4.966 ± 0.595
0.993ThrMet: 0.993 ± 0.244
2.75ThrAsn: 2.75 ± 0.458
2.674ThrPro: 2.674 ± 0.391
2.445ThrGln: 2.445 ± 0.59
2.674ThrArg: 2.674 ± 0.425
3.667ThrSer: 3.667 ± 0.451
3.591ThrThr: 3.591 ± 0.617
4.431ThrVal: 4.431 ± 0.739
1.299ThrTrp: 1.299 ± 0.374
1.07ThrTyr: 1.07 ± 0.331
0.0ThrXaa: 0.0 ± 0.0
Val
6.112ValAla: 6.112 ± 0.712
0.611ValCys: 0.611 ± 0.207
4.126ValAsp: 4.126 ± 0.615
3.438ValGlu: 3.438 ± 0.625
2.368ValPhe: 2.368 ± 0.529
3.438ValGly: 3.438 ± 0.446
0.993ValHis: 0.993 ± 0.276
4.737ValIle: 4.737 ± 0.622
4.355ValLys: 4.355 ± 0.592
4.202ValLeu: 4.202 ± 0.575
1.604ValMet: 1.604 ± 0.31
3.667ValAsn: 3.667 ± 0.536
2.75ValPro: 2.75 ± 0.405
2.292ValGln: 2.292 ± 0.491
4.049ValArg: 4.049 ± 0.555
4.202ValSer: 4.202 ± 0.554
4.584ValThr: 4.584 ± 0.66
4.278ValVal: 4.278 ± 0.54
1.146ValTrp: 1.146 ± 0.249
1.91ValTyr: 1.91 ± 0.358
0.0ValXaa: 0.0 ± 0.0
Trp
1.07TrpAla: 1.07 ± 0.29
0.229TrpCys: 0.229 ± 0.148
0.917TrpAsp: 0.917 ± 0.199
1.375TrpGlu: 1.375 ± 0.344
0.611TrpPhe: 0.611 ± 0.188
0.84TrpGly: 0.84 ± 0.209
0.688TrpHis: 0.688 ± 0.303
0.611TrpIle: 0.611 ± 0.241
1.146TrpLys: 1.146 ± 0.35
2.674TrpLeu: 2.674 ± 0.482
0.382TrpMet: 0.382 ± 0.222
0.611TrpAsn: 0.611 ± 0.213
0.458TrpPro: 0.458 ± 0.183
0.764TrpGln: 0.764 ± 0.192
1.681TrpArg: 1.681 ± 0.314
1.07TrpSer: 1.07 ± 0.251
0.917TrpThr: 0.917 ± 0.266
1.299TrpVal: 1.299 ± 0.285
0.076TrpTrp: 0.076 ± 0.081
0.611TrpTyr: 0.611 ± 0.188
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.056TyrAla: 3.056 ± 0.423
0.688TyrCys: 0.688 ± 0.235
2.292TyrAsp: 2.292 ± 0.448
1.91TyrGlu: 1.91 ± 0.346
1.528TyrPhe: 1.528 ± 0.47
2.139TyrGly: 2.139 ± 0.39
0.535TyrHis: 0.535 ± 0.218
1.222TyrIle: 1.222 ± 0.364
0.84TyrLys: 0.84 ± 0.237
2.063TyrLeu: 2.063 ± 0.41
0.764TyrMet: 0.764 ± 0.259
1.681TyrAsn: 1.681 ± 0.449
1.604TyrPro: 1.604 ± 0.316
1.452TyrGln: 1.452 ± 0.333
2.445TyrArg: 2.445 ± 0.428
1.986TyrSer: 1.986 ± 0.441
1.834TyrThr: 1.834 ± 0.365
1.986TyrVal: 1.986 ± 0.389
0.611TyrTrp: 0.611 ± 0.219
1.146TyrTyr: 1.146 ± 0.428
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 66 proteins (13090 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski