Trypanosoma cruzi marinkellei

Taxonomy: cellular organisms; Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum; Trypanosoma cruzi

Average proteome isoelectric point is 6.54

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10052 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|K2NH72|K2NH72_TRYCR Dispersed gene family protein 1 (DGF-1) putative (Fragment) OS=Trypanosoma cruzi marinkellei OX=85056 GN=MOQ_007938 PE=4 SV=1
MM1 pKa = 6.85MTTCRR6 pKa = 11.84LLCALLVLALCCCPSVCGTEE26 pKa = 3.8VDD28 pKa = 3.92VNKK31 pKa = 10.94DD32 pKa = 3.29KK33 pKa = 11.6GNSSTPSQPGGTGVLGPGEE52 pKa = 4.28PQSLSQEE59 pKa = 4.08PGIQSGQSGEE69 pKa = 5.54DD70 pKa = 3.3GMQHH74 pKa = 5.33NTEE77 pKa = 4.17QVPGQPADD85 pKa = 3.33TALTEE90 pKa = 4.18NPNAGTPGPITEE102 pKa = 4.22QGPRR106 pKa = 11.84DD107 pKa = 3.84TDD109 pKa = 3.51TQEE112 pKa = 4.1AQSGDD117 pKa = 3.53TAASGQTDD125 pKa = 3.79TNVDD129 pKa = 3.64DD130 pKa = 4.3SAEE133 pKa = 4.27TTTANAPTTATTTTTAPEE151 pKa = 4.33APSTTTTEE159 pKa = 4.19APTTTTTRR167 pKa = 11.84APSRR171 pKa = 11.84LPEE174 pKa = 5.1IDD176 pKa = 3.88GSLSSSAWVIAPLLLAVSALAYY198 pKa = 6.39TTLGG202 pKa = 3.38

Molecular weight: 20.33 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|K2NUY0|K2NUY0_TRYCR DNA-directed RNA polymerase subunit OS=Trypanosoma cruzi marinkellei OX=85056 GN=MOQ_003349 PE=3 SV=1
MM1 pKa = 8.11DD2 pKa = 3.94VAQFLNVRR10 pKa = 11.84VEE12 pKa = 3.93EE13 pKa = 4.08LAAFSALLFRR23 pKa = 11.84KK24 pKa = 10.11RR25 pKa = 11.84PRR27 pKa = 11.84HH28 pKa = 4.86EE29 pKa = 3.92NEE31 pKa = 4.04GAFSCTARR39 pKa = 11.84SVVHH43 pKa = 5.44YY44 pKa = 9.69RR45 pKa = 11.84RR46 pKa = 11.84PSSANVPLSDD56 pKa = 3.94VMRR59 pKa = 11.84LAKK62 pKa = 10.1FRR64 pKa = 11.84SRR66 pKa = 11.84RR67 pKa = 11.84SKK69 pKa = 10.66RR70 pKa = 11.84FVRR73 pKa = 11.84LLAAEE78 pKa = 4.58EE79 pKa = 4.48PPPATPKK86 pKa = 10.57AVEE89 pKa = 4.08EE90 pKa = 4.32EE91 pKa = 4.0KK92 pKa = 11.32GRR94 pKa = 11.84MQKK97 pKa = 9.91KK98 pKa = 9.55RR99 pKa = 11.84RR100 pKa = 11.84LLTYY104 pKa = 10.15RR105 pKa = 11.84AWCLLLRR112 pKa = 11.84RR113 pKa = 11.84RR114 pKa = 11.84RR115 pKa = 11.84RR116 pKa = 11.84FLLRR120 pKa = 11.84RR121 pKa = 11.84RR122 pKa = 11.84ATTRR126 pKa = 11.84RR127 pKa = 11.84RR128 pKa = 11.84IRR130 pKa = 11.84RR131 pKa = 11.84RR132 pKa = 11.84IISLRR137 pKa = 11.84YY138 pKa = 9.86GKK140 pKa = 7.89TQLPFCNCGSAAGAPPPSFPPCLSTQSSSSGGGRR174 pKa = 11.84TAVLWLPSHH183 pKa = 6.17WRR185 pKa = 11.84FCRR188 pKa = 11.84RR189 pKa = 11.84FHH191 pKa = 6.73YY192 pKa = 10.69SVFKK196 pKa = 10.55TRR198 pKa = 11.84INGCSSSPDD207 pKa = 3.51DD208 pKa = 4.56DD209 pKa = 4.41FSRR212 pKa = 11.84LVNVRR217 pKa = 11.84IAVPTKK223 pKa = 8.66SQRR226 pKa = 11.84KK227 pKa = 4.49QHH229 pKa = 6.18RR230 pKa = 11.84VLQRR234 pKa = 11.84WAARR238 pKa = 11.84LPSCCALGKK247 pKa = 9.85PPGRR251 pKa = 11.84IKK253 pKa = 10.52SKK255 pKa = 10.33PMAVPPPLCFAAEE268 pKa = 4.0RR269 pKa = 11.84SHH271 pKa = 5.42MCVWAIQPRR280 pKa = 11.84EE281 pKa = 4.0NGHH284 pKa = 7.09LLTADD289 pKa = 3.41EE290 pKa = 4.61VMDD293 pKa = 3.3ILMIHH298 pKa = 6.09SCKK301 pKa = 10.4APPVALHH308 pKa = 5.93TRR310 pKa = 11.84DD311 pKa = 4.1LATMAQTSVGSVPHH325 pKa = 5.71EE326 pKa = 4.17KK327 pKa = 9.71CWRR330 pKa = 11.84RR331 pKa = 11.84TEE333 pKa = 3.98SAVFYY338 pKa = 10.44GYY340 pKa = 8.58MWSLGKK346 pKa = 10.58AMSKK350 pKa = 10.47SKK352 pKa = 9.94WLLRR356 pKa = 11.84GDD358 pKa = 4.25TEE360 pKa = 4.36PCASDD365 pKa = 3.12TTPIVVPVILLRR377 pKa = 11.84NEE379 pKa = 4.58DD380 pKa = 3.73GDD382 pKa = 3.65GGNYY386 pKa = 9.83HH387 pKa = 7.05LVASTPVYY395 pKa = 9.46IGARR399 pKa = 11.84ARR401 pKa = 11.84RR402 pKa = 11.84SLDD405 pKa = 3.04MRR407 pKa = 11.84LISHH411 pKa = 7.47WNPCSAPKK419 pKa = 9.62PLCSMFEE426 pKa = 3.88LWCCVDD432 pKa = 3.51AVSAKK437 pKa = 10.38GADD440 pKa = 3.64VPSTRR445 pKa = 11.84DD446 pKa = 3.11DD447 pKa = 3.72SFILKK452 pKa = 9.26WIRR455 pKa = 11.84GRR457 pKa = 11.84VHH459 pKa = 6.81AALGRR464 pKa = 11.84WCRR467 pKa = 11.84VNRR470 pKa = 11.84ISSFTEE476 pKa = 3.7QEE478 pKa = 4.05GCEE481 pKa = 4.18TNNNSSSLITRR492 pKa = 11.84TTVCVFPSIPPNLEE506 pKa = 4.2TIDD509 pKa = 4.53HH510 pKa = 6.59ISFPVHH516 pKa = 5.77RR517 pKa = 11.84CVMSILFLSKK527 pKa = 10.92GSFPQSDD534 pKa = 3.86TTGSAVRR541 pKa = 11.84LHH543 pKa = 6.96RR544 pKa = 11.84MRR546 pKa = 11.84HH547 pKa = 3.92FQFARR552 pKa = 11.84KK553 pKa = 9.13LFSSLSDD560 pKa = 3.25TTATAWRR567 pKa = 11.84TMCHH571 pKa = 6.93DD572 pKa = 4.06DD573 pKa = 5.3EE574 pKa = 5.97KK575 pKa = 11.15NAWAFRR581 pKa = 11.84LCQSLGYY588 pKa = 9.27RR589 pKa = 11.84RR590 pKa = 11.84NVRR593 pKa = 11.84IIGEE597 pKa = 4.24EE598 pKa = 3.86EE599 pKa = 4.35RR600 pKa = 11.84EE601 pKa = 4.2TLLSLIGCPAFTDD614 pKa = 3.79VSGNDD619 pKa = 3.0ASFQISRR626 pKa = 11.84MARR629 pKa = 11.84LRR631 pKa = 11.84CSPSNAHH638 pKa = 5.87QRR640 pKa = 11.84VLLKK644 pKa = 9.96FAARR648 pKa = 11.84GGRR651 pKa = 11.84EE652 pKa = 3.83HH653 pKa = 6.27QRR655 pKa = 11.84EE656 pKa = 4.2GSALFVLKK664 pKa = 10.27PGSPAEE670 pKa = 4.05LFHH673 pKa = 8.03VGAVTSAPFFSMRR686 pKa = 11.84FGTRR690 pKa = 11.84VAYY693 pKa = 10.09AWVWDD698 pKa = 3.96DD699 pKa = 5.44AGWEE703 pKa = 4.09LVKK706 pKa = 10.71LYY708 pKa = 11.06NRR710 pKa = 11.84FALRR714 pKa = 11.84TVSRR718 pKa = 11.84EE719 pKa = 3.58EE720 pKa = 3.83TEE722 pKa = 4.17IFHH725 pKa = 6.98EE726 pKa = 5.2GPKK729 pKa = 9.6MGSATEE735 pKa = 3.98HH736 pKa = 6.37SGAGSGGNIYY746 pKa = 10.67FFLRR750 pKa = 11.84PLKK753 pKa = 10.11RR754 pKa = 11.84SHH756 pKa = 5.47VLYY759 pKa = 10.41RR760 pKa = 11.84FLRR763 pKa = 11.84ILPFIFLAVLLPLLLLRR780 pKa = 11.84AKK782 pKa = 9.75QVNKK786 pKa = 10.71SGITGMARR794 pKa = 11.84RR795 pKa = 11.84GG796 pKa = 3.34

Molecular weight: 90.02 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

10052

0

10052

4945837

10

5150

492.0

54.58

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.372 ± 0.024

2.091 ± 0.011

4.85 ± 0.014

6.977 ± 0.03

3.774 ± 0.014

6.736 ± 0.027

2.54 ± 0.01

3.866 ± 0.016

4.372 ± 0.018

9.699 ± 0.025

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.505 ± 0.008

3.65 ± 0.014

4.837 ± 0.019

3.728 ± 0.016

6.882 ± 0.022

7.988 ± 0.022

5.838 ± 0.015

7.626 ± 0.023

1.21 ± 0.008

2.458 ± 0.01
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski