Amino acid dipepetide frequency for Undibacterium piscinae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.456AlaAla: 13.456 ± 0.176
1.169AlaCys: 1.169 ± 0.036
5.678AlaAsp: 5.678 ± 0.078
6.129AlaGlu: 6.129 ± 0.098
3.662AlaPhe: 3.662 ± 0.061
8.389AlaGly: 8.389 ± 0.129
2.298AlaHis: 2.298 ± 0.052
6.397AlaIle: 6.397 ± 0.09
5.325AlaLys: 5.325 ± 0.078
12.447AlaLeu: 12.447 ± 0.135
3.182AlaMet: 3.182 ± 0.06
3.76AlaAsn: 3.76 ± 0.074
4.309AlaPro: 4.309 ± 0.081
5.222AlaGln: 5.222 ± 0.082
5.654AlaArg: 5.654 ± 0.09
7.461AlaSer: 7.461 ± 0.108
5.532AlaThr: 5.532 ± 0.098
7.073AlaVal: 7.073 ± 0.108
1.35AlaTrp: 1.35 ± 0.039
2.853AlaTyr: 2.853 ± 0.05
0.0AlaXaa: 0.0 ± 0.0
Cys
1.005CysAla: 1.005 ± 0.031
0.139CysCys: 0.139 ± 0.012
0.53CysAsp: 0.53 ± 0.021
0.477CysGlu: 0.477 ± 0.02
0.323CysPhe: 0.323 ± 0.017
0.966CysGly: 0.966 ± 0.032
0.259CysHis: 0.259 ± 0.017
0.519CysIle: 0.519 ± 0.023
0.335CysLys: 0.335 ± 0.016
0.924CysLeu: 0.924 ± 0.028
0.247CysMet: 0.247 ± 0.017
0.283CysAsn: 0.283 ± 0.016
0.46CysPro: 0.46 ± 0.022
0.33CysGln: 0.33 ± 0.015
0.464CysArg: 0.464 ± 0.022
0.648CysSer: 0.648 ± 0.027
0.439CysThr: 0.439 ± 0.025
0.621CysVal: 0.621 ± 0.026
0.127CysTrp: 0.127 ± 0.012
0.252CysTyr: 0.252 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
6.108AspAla: 6.108 ± 0.074
0.467AspCys: 0.467 ± 0.021
2.514AspAsp: 2.514 ± 0.06
2.968AspGlu: 2.968 ± 0.064
2.252AspPhe: 2.252 ± 0.046
4.056AspGly: 4.056 ± 0.06
1.01AspHis: 1.01 ± 0.041
3.046AspIle: 3.046 ± 0.062
2.449AspLys: 2.449 ± 0.051
5.334AspLeu: 5.334 ± 0.075
1.361AspMet: 1.361 ± 0.037
1.597AspAsn: 1.597 ± 0.038
2.231AspPro: 2.231 ± 0.047
2.101AspGln: 2.101 ± 0.045
2.29AspArg: 2.29 ± 0.054
2.852AspSer: 2.852 ± 0.058
2.56AspThr: 2.56 ± 0.062
3.554AspVal: 3.554 ± 0.059
0.827AspTrp: 0.827 ± 0.029
1.553AspTyr: 1.553 ± 0.042
0.0AspXaa: 0.0 ± 0.0
Glu
5.421GluAla: 5.421 ± 0.094
0.409GluCys: 0.409 ± 0.019
2.184GluAsp: 2.184 ± 0.051
2.654GluGlu: 2.654 ± 0.06
2.073GluPhe: 2.073 ± 0.045
2.98GluGly: 2.98 ± 0.059
1.296GluHis: 1.296 ± 0.043
3.675GluIle: 3.675 ± 0.061
3.038GluLys: 3.038 ± 0.061
6.12GluLeu: 6.12 ± 0.089
1.571GluMet: 1.571 ± 0.037
2.011GluAsn: 2.011 ± 0.05
1.773GluPro: 1.773 ± 0.05
3.259GluGln: 3.259 ± 0.073
3.496GluArg: 3.496 ± 0.058
2.952GluSer: 2.952 ± 0.054
2.665GluThr: 2.665 ± 0.056
3.815GluVal: 3.815 ± 0.059
0.673GluTrp: 0.673 ± 0.024
1.3GluTyr: 1.3 ± 0.037
0.0GluXaa: 0.0 ± 0.0
Phe
4.108PheAla: 4.108 ± 0.065
0.447PheCys: 0.447 ± 0.021
2.46PheAsp: 2.46 ± 0.048
2.083PheGlu: 2.083 ± 0.048
1.753PhePhe: 1.753 ± 0.05
3.27PheGly: 3.27 ± 0.059
0.75PheHis: 0.75 ± 0.029
2.073PheIle: 2.073 ± 0.051
1.666PheLys: 1.666 ± 0.044
3.382PheLeu: 3.382 ± 0.062
0.939PheMet: 0.939 ± 0.031
1.515PheAsn: 1.515 ± 0.037
1.577PhePro: 1.577 ± 0.044
1.247PheGln: 1.247 ± 0.036
1.755PheArg: 1.755 ± 0.044
3.164PheSer: 3.164 ± 0.064
1.961PheThr: 1.961 ± 0.045
2.593PheVal: 2.593 ± 0.05
0.543PheTrp: 0.543 ± 0.025
1.085PheTyr: 1.085 ± 0.036
0.0PheXaa: 0.0 ± 0.0
Gly
6.839GlyAla: 6.839 ± 0.114
0.748GlyCys: 0.748 ± 0.028
3.543GlyAsp: 3.543 ± 0.088
3.723GlyGlu: 3.723 ± 0.067
3.195GlyPhe: 3.195 ± 0.067
5.411GlyGly: 5.411 ± 0.104
1.658GlyHis: 1.658 ± 0.04
4.641GlyIle: 4.641 ± 0.064
4.388GlyLys: 4.388 ± 0.074
7.615GlyLeu: 7.615 ± 0.098
2.345GlyMet: 2.345 ± 0.047
2.843GlyAsn: 2.843 ± 0.111
1.961GlyPro: 1.961 ± 0.044
2.946GlyGln: 2.946 ± 0.061
3.762GlyArg: 3.762 ± 0.069
4.791GlySer: 4.791 ± 0.091
3.73GlyThr: 3.73 ± 0.105
5.526GlyVal: 5.526 ± 0.08
1.089GlyTrp: 1.089 ± 0.034
2.329GlyTyr: 2.329 ± 0.048
0.0GlyXaa: 0.0 ± 0.0
His
2.471HisAla: 2.471 ± 0.06
0.299HisCys: 0.299 ± 0.017
1.06HisAsp: 1.06 ± 0.028
1.124HisGlu: 1.124 ± 0.034
0.946HisPhe: 0.946 ± 0.033
1.764HisGly: 1.764 ± 0.046
0.652HisHis: 0.652 ± 0.026
1.232HisIle: 1.232 ± 0.037
0.755HisLys: 0.755 ± 0.027
2.292HisLeu: 2.292 ± 0.056
0.492HisMet: 0.492 ± 0.023
0.626HisAsn: 0.626 ± 0.026
1.187HisPro: 1.187 ± 0.03
1.01HisGln: 1.01 ± 0.034
1.065HisArg: 1.065 ± 0.035
1.278HisSer: 1.278 ± 0.034
1.171HisThr: 1.171 ± 0.053
1.314HisVal: 1.314 ± 0.041
0.329HisTrp: 0.329 ± 0.019
0.74HisTyr: 0.74 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
7.416IleAla: 7.416 ± 0.077
0.594IleCys: 0.594 ± 0.022
3.459IleAsp: 3.459 ± 0.054
3.578IleGlu: 3.578 ± 0.067
2.003IlePhe: 2.003 ± 0.053
4.582IleGly: 4.582 ± 0.077
1.064IleHis: 1.064 ± 0.033
2.682IleIle: 2.682 ± 0.066
2.629IleLys: 2.629 ± 0.048
5.23IleLeu: 5.23 ± 0.074
1.19IleMet: 1.19 ± 0.037
2.299IleAsn: 2.299 ± 0.051
2.584IlePro: 2.584 ± 0.055
1.853IleGln: 1.853 ± 0.042
2.991IleArg: 2.991 ± 0.057
4.315IleSer: 4.315 ± 0.069
3.016IleThr: 3.016 ± 0.062
3.999IleVal: 3.999 ± 0.083
0.649IleTrp: 0.649 ± 0.024
1.367IleTyr: 1.367 ± 0.036
0.0IleXaa: 0.0 ± 0.0
Lys
4.608LysAla: 4.608 ± 0.079
0.218LysCys: 0.218 ± 0.015
2.316LysAsp: 2.316 ± 0.049
2.345LysGlu: 2.345 ± 0.051
1.602LysPhe: 1.602 ± 0.042
2.73LysGly: 2.73 ± 0.06
1.001LysHis: 1.001 ± 0.03
2.977LysIle: 2.977 ± 0.057
2.514LysLys: 2.514 ± 0.056
5.387LysLeu: 5.387 ± 0.084
1.514LysMet: 1.514 ± 0.048
2.16LysAsn: 2.16 ± 0.049
2.37LysPro: 2.37 ± 0.06
2.188LysGln: 2.188 ± 0.043
2.566LysArg: 2.566 ± 0.052
2.858LysSer: 2.858 ± 0.056
2.797LysThr: 2.797 ± 0.054
3.007LysVal: 3.007 ± 0.062
0.491LysTrp: 0.491 ± 0.021
1.051LysTyr: 1.051 ± 0.038
0.0LysXaa: 0.0 ± 0.0
Leu
13.078LeuAla: 13.078 ± 0.139
1.064LeuCys: 1.064 ± 0.034
5.648LeuAsp: 5.648 ± 0.084
5.511LeuGlu: 5.511 ± 0.088
3.857LeuPhe: 3.857 ± 0.07
7.629LeuGly: 7.629 ± 0.112
2.361LeuHis: 2.361 ± 0.052
5.808LeuIle: 5.808 ± 0.079
4.863LeuLys: 4.863 ± 0.072
11.618LeuLeu: 11.618 ± 0.153
2.732LeuMet: 2.732 ± 0.049
3.991LeuAsn: 3.991 ± 0.073
5.587LeuPro: 5.587 ± 0.08
4.767LeuGln: 4.767 ± 0.089
6.283LeuArg: 6.283 ± 0.087
8.147LeuSer: 8.147 ± 0.101
5.453LeuThr: 5.453 ± 0.078
6.677LeuVal: 6.677 ± 0.098
1.166LeuTrp: 1.166 ± 0.035
2.256LeuTyr: 2.256 ± 0.054
0.0LeuXaa: 0.0 ± 0.0
Met
2.787MetAla: 2.787 ± 0.053
0.2MetCys: 0.2 ± 0.014
1.231MetAsp: 1.231 ± 0.037
1.278MetGlu: 1.278 ± 0.032
0.882MetPhe: 0.882 ± 0.031
1.82MetGly: 1.82 ± 0.044
0.595MetHis: 0.595 ± 0.027
1.365MetIle: 1.365 ± 0.036
1.292MetLys: 1.292 ± 0.036
3.139MetLeu: 3.139 ± 0.055
0.776MetMet: 0.776 ± 0.03
1.066MetAsn: 1.066 ± 0.035
1.486MetPro: 1.486 ± 0.036
1.442MetGln: 1.442 ± 0.032
1.616MetArg: 1.616 ± 0.035
1.953MetSer: 1.953 ± 0.044
1.552MetThr: 1.552 ± 0.04
1.743MetVal: 1.743 ± 0.041
0.228MetTrp: 0.228 ± 0.014
0.486MetTyr: 0.486 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
3.927AsnAla: 3.927 ± 0.081
0.34AsnCys: 0.34 ± 0.018
1.718AsnAsp: 1.718 ± 0.043
1.69AsnGlu: 1.69 ± 0.043
1.425AsnPhe: 1.425 ± 0.036
2.887AsnGly: 2.887 ± 0.061
0.712AsnHis: 0.712 ± 0.027
2.079AsnIle: 2.079 ± 0.049
1.622AsnLys: 1.622 ± 0.043
3.954AsnLeu: 3.954 ± 0.067
0.884AsnMet: 0.884 ± 0.028
1.415AsnAsn: 1.415 ± 0.054
2.069AsnPro: 2.069 ± 0.048
1.582AsnGln: 1.582 ± 0.043
1.859AsnArg: 1.859 ± 0.045
2.256AsnSer: 2.256 ± 0.064
1.985AsnThr: 1.985 ± 0.052
2.288AsnVal: 2.288 ± 0.052
0.553AsnTrp: 0.553 ± 0.025
1.066AsnTyr: 1.066 ± 0.036
0.0AsnXaa: 0.0 ± 0.0
Pro
5.048ProAla: 5.048 ± 0.082
0.362ProCys: 0.362 ± 0.019
2.706ProAsp: 2.706 ± 0.051
3.084ProGlu: 3.084 ± 0.064
1.64ProPhe: 1.64 ± 0.045
3.215ProGly: 3.215 ± 0.06
0.925ProHis: 0.925 ± 0.031
2.102ProIle: 2.102 ± 0.048
1.891ProLys: 1.891 ± 0.042
4.4ProLeu: 4.4 ± 0.07
1.125ProMet: 1.125 ± 0.033
1.428ProAsn: 1.428 ± 0.034
1.654ProPro: 1.654 ± 0.05
1.895ProGln: 1.895 ± 0.046
1.908ProArg: 1.908 ± 0.042
2.551ProSer: 2.551 ± 0.044
1.967ProThr: 1.967 ± 0.043
3.587ProVal: 3.587 ± 0.066
0.538ProTrp: 0.538 ± 0.022
1.162ProTyr: 1.162 ± 0.038
0.0ProXaa: 0.0 ± 0.0
Gln
5.398GlnAla: 5.398 ± 0.087
0.295GlnCys: 0.295 ± 0.019
1.909GlnAsp: 1.909 ± 0.043
2.225GlnGlu: 2.225 ± 0.055
1.644GlnPhe: 1.644 ± 0.039
2.806GlnGly: 2.806 ± 0.057
1.149GlnHis: 1.149 ± 0.037
2.778GlnIle: 2.778 ± 0.056
1.929GlnLys: 1.929 ± 0.051
5.011GlnLeu: 5.011 ± 0.087
1.186GlnMet: 1.186 ± 0.032
1.506GlnAsn: 1.506 ± 0.042
1.588GlnPro: 1.588 ± 0.044
2.665GlnGln: 2.665 ± 0.071
2.992GlnArg: 2.992 ± 0.064
2.548GlnSer: 2.548 ± 0.055
2.237GlnThr: 2.237 ± 0.046
3.096GlnVal: 3.096 ± 0.061
0.564GlnTrp: 0.564 ± 0.022
1.012GlnTyr: 1.012 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
5.076ArgAla: 5.076 ± 0.076
0.467ArgCys: 0.467 ± 0.02
2.856ArgAsp: 2.856 ± 0.05
3.155ArgGlu: 3.155 ± 0.062
2.273ArgPhe: 2.273 ± 0.045
3.209ArgGly: 3.209 ± 0.054
1.348ArgHis: 1.348 ± 0.041
3.441ArgIle: 3.441 ± 0.06
2.334ArgLys: 2.334 ± 0.053
6.141ArgLeu: 6.141 ± 0.097
1.564ArgMet: 1.564 ± 0.04
2.013ArgAsn: 2.013 ± 0.042
2.083ArgPro: 2.083 ± 0.05
2.696ArgGln: 2.696 ± 0.059
2.974ArgArg: 2.974 ± 0.065
3.323ArgSer: 3.323 ± 0.058
2.406ArgThr: 2.406 ± 0.053
3.519ArgVal: 3.519 ± 0.064
0.791ArgTrp: 0.791 ± 0.028
1.747ArgTyr: 1.747 ± 0.04
0.0ArgXaa: 0.0 ± 0.0
Ser
7.314SerAla: 7.314 ± 0.108
0.578SerCys: 0.578 ± 0.027
3.296SerAsp: 3.296 ± 0.049
3.405SerGlu: 3.405 ± 0.056
2.685SerPhe: 2.685 ± 0.054
5.812SerGly: 5.812 ± 0.118
1.366SerHis: 1.366 ± 0.039
3.72SerIle: 3.72 ± 0.067
2.972SerLys: 2.972 ± 0.057
7.352SerLeu: 7.352 ± 0.105
1.696SerMet: 1.696 ± 0.039
2.356SerAsn: 2.356 ± 0.064
2.603SerPro: 2.603 ± 0.051
2.542SerGln: 2.542 ± 0.061
3.234SerArg: 3.234 ± 0.057
4.476SerSer: 4.476 ± 0.076
3.338SerThr: 3.338 ± 0.066
4.481SerVal: 4.481 ± 0.088
0.868SerTrp: 0.868 ± 0.028
1.82SerTyr: 1.82 ± 0.05
0.0SerXaa: 0.0 ± 0.0
Thr
5.538ThrAla: 5.538 ± 0.114
0.409ThrCys: 0.409 ± 0.018
2.54ThrAsp: 2.54 ± 0.059
2.686ThrGlu: 2.686 ± 0.059
1.673ThrPhe: 1.673 ± 0.046
4.18ThrGly: 4.18 ± 0.083
1.129ThrHis: 1.129 ± 0.036
2.981ThrIle: 2.981 ± 0.061
1.925ThrLys: 1.925 ± 0.051
6.109ThrLeu: 6.109 ± 0.085
1.199ThrMet: 1.199 ± 0.029
1.591ThrAsn: 1.591 ± 0.043
2.998ThrPro: 2.998 ± 0.055
2.107ThrGln: 2.107 ± 0.047
2.496ThrArg: 2.496 ± 0.055
3.22ThrSer: 3.22 ± 0.058
2.904ThrThr: 2.904 ± 0.062
3.886ThrVal: 3.886 ± 0.132
0.568ThrTrp: 0.568 ± 0.026
1.318ThrTyr: 1.318 ± 0.058
0.0ThrXaa: 0.0 ± 0.0
Val
8.018ValAla: 8.018 ± 0.111
0.685ValCys: 0.685 ± 0.03
3.556ValAsp: 3.556 ± 0.06
3.507ValGlu: 3.507 ± 0.061
2.715ValPhe: 2.715 ± 0.051
4.642ValGly: 4.642 ± 0.084
1.333ValHis: 1.333 ± 0.042
4.188ValIle: 4.188 ± 0.072
3.211ValLys: 3.211 ± 0.067
7.243ValLeu: 7.243 ± 0.091
1.919ValMet: 1.919 ± 0.047
2.556ValAsn: 2.556 ± 0.057
2.882ValPro: 2.882 ± 0.063
2.496ValGln: 2.496 ± 0.049
3.507ValArg: 3.507 ± 0.059
4.643ValSer: 4.643 ± 0.074
3.835ValThr: 3.835 ± 0.101
4.978ValVal: 4.978 ± 0.079
0.834ValTrp: 0.834 ± 0.03
1.563ValTyr: 1.563 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.004TrpAla: 1.004 ± 0.031
0.152TrpCys: 0.152 ± 0.013
0.589TrpAsp: 0.589 ± 0.025
0.511TrpGlu: 0.511 ± 0.023
0.509TrpPhe: 0.509 ± 0.021
0.757TrpGly: 0.757 ± 0.027
0.355TrpHis: 0.355 ± 0.016
0.727TrpIle: 0.727 ± 0.027
0.563TrpLys: 0.563 ± 0.021
1.804TrpLeu: 1.804 ± 0.046
0.451TrpMet: 0.451 ± 0.022
0.486TrpAsn: 0.486 ± 0.021
0.493TrpPro: 0.493 ± 0.021
0.815TrpGln: 0.815 ± 0.031
0.893TrpArg: 0.893 ± 0.035
0.811TrpSer: 0.811 ± 0.028
0.526TrpThr: 0.526 ± 0.023
0.809TrpVal: 0.809 ± 0.028
0.236TrpTrp: 0.236 ± 0.015
0.306TrpTyr: 0.306 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.725TyrAla: 2.725 ± 0.055
0.306TyrCys: 0.306 ± 0.017
1.333TyrAsp: 1.333 ± 0.04
1.233TyrGlu: 1.233 ± 0.036
1.262TyrPhe: 1.262 ± 0.036
1.978TyrGly: 1.978 ± 0.049
0.549TyrHis: 0.549 ± 0.022
1.07TyrIle: 1.07 ± 0.03
0.998TyrLys: 0.998 ± 0.033
2.995TyrLeu: 2.995 ± 0.063
0.564TyrMet: 0.564 ± 0.023
0.808TyrAsn: 0.808 ± 0.034
1.295TyrPro: 1.295 ± 0.041
1.375TyrGln: 1.375 ± 0.04
1.612TyrArg: 1.612 ± 0.039
1.666TyrSer: 1.666 ± 0.064
1.384TyrThr: 1.384 ± 0.049
1.743TyrVal: 1.743 ± 0.047
0.371TyrTrp: 0.371 ± 0.017
0.721TyrTyr: 0.721 ± 0.029
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3332 proteins (1065376 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski