Amino acid dipepetide frequency for Catellatospora citrea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.995AlaAla: 23.995 ± 0.147	1.101AlaCys: 1.101 ± 0.021	9.029AlaAsp: 9.029 ± 0.062	7.941AlaGlu: 7.941 ± 0.083	3.555AlaPhe: 3.555 ± 0.042	13.656AlaGly: 13.656 ± 0.08	2.732AlaHis: 2.732 ± 0.04	4.167AlaIle: 4.167 ± 0.044	2.709AlaLys: 2.709 ± 0.039	14.622AlaLeu: 14.622 ± 0.104	2.777AlaMet: 2.777 ± 0.033	2.439AlaAsn: 2.439 ± 0.04	6.924AlaPro: 6.924 ± 0.061	4.335AlaGln: 4.335 ± 0.045	9.727AlaArg: 9.727 ± 0.079	5.743AlaSer: 5.743 ± 0.054	8.071AlaThr: 8.071 ± 0.063	12.992AlaVal: 12.992 ± 0.091	2.121AlaTrp: 2.121 ± 0.03	2.97AlaTyr: 2.97 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	1.056CysAla: 1.056 ± 0.019	0.117CysCys: 0.117 ± 0.007	0.503CysAsp: 0.503 ± 0.014	0.337CysGlu: 0.337 ± 0.011	0.213CysPhe: 0.213 ± 0.01	0.912CysGly: 0.912 ± 0.021	0.21CysHis: 0.21 ± 0.008	0.176CysIle: 0.176 ± 0.008	0.104CysLys: 0.104 ± 0.007	0.752CysLeu: 0.752 ± 0.018	0.109CysMet: 0.109 ± 0.006	0.167CysAsn: 0.167 ± 0.009	0.45CysPro: 0.45 ± 0.015	0.191CysGln: 0.191 ± 0.01	0.6CysArg: 0.6 ± 0.014	0.401CysSer: 0.401 ± 0.013	0.493CysThr: 0.493 ± 0.014	0.631CysVal: 0.631 ± 0.017	0.131CysTrp: 0.131 ± 0.007	0.174CysTyr: 0.174 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	7.615AspAla: 7.615 ± 0.063	0.421AspCys: 0.421 ± 0.014	3.672AspAsp: 3.672 ± 0.04	3.558AspGlu: 3.558 ± 0.042	1.6AspPhe: 1.6 ± 0.026	6.482AspGly: 6.482 ± 0.06	1.338AspHis: 1.338 ± 0.025	1.729AspIle: 1.729 ± 0.031	1.067AspLys: 1.067 ± 0.022	6.617AspLeu: 6.617 ± 0.058	0.801AspMet: 0.801 ± 0.018	1.129AspAsn: 1.129 ± 0.026	4.708AspPro: 4.708 ± 0.048	1.711AspGln: 1.711 ± 0.025	4.798AspArg: 4.798 ± 0.051	2.279AspSer: 2.279 ± 0.027	3.212AspThr: 3.212 ± 0.038	4.896AspVal: 4.896 ± 0.047	1.035AspTrp: 1.035 ± 0.023	1.204AspTyr: 1.204 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	5.872GluAla: 5.872 ± 0.071	0.305GluCys: 0.305 ± 0.012	2.049GluAsp: 2.049 ± 0.03	2.13GluGlu: 2.13 ± 0.033	1.479GluPhe: 1.479 ± 0.023	3.068GluGly: 3.068 ± 0.04	1.539GluHis: 1.539 ± 0.024	2.093GluIle: 2.093 ± 0.028	0.961GluLys: 0.961 ± 0.024	6.425GluLeu: 6.425 ± 0.063	0.769GluMet: 0.769 ± 0.018	0.835GluAsn: 0.835 ± 0.02	3.192GluPro: 3.192 ± 0.044	2.502GluGln: 2.502 ± 0.031	4.273GluArg: 4.273 ± 0.043	2.135GluSer: 2.135 ± 0.033	2.308GluThr: 2.308 ± 0.032	4.145GluVal: 4.145 ± 0.039	0.673GluTrp: 0.673 ± 0.017	0.986GluTyr: 0.986 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	4.022PheAla: 4.022 ± 0.044	0.25PheCys: 0.25 ± 0.009	2.094PheAsp: 2.094 ± 0.033	1.245PheGlu: 1.245 ± 0.021	0.865PhePhe: 0.865 ± 0.019	3.141PheGly: 3.141 ± 0.039	0.586PheHis: 0.586 ± 0.014	0.808PheIle: 0.808 ± 0.021	0.491PheLys: 0.491 ± 0.013	2.529PheLeu: 2.529 ± 0.034	0.396PheMet: 0.396 ± 0.012	0.661PheAsn: 0.661 ± 0.018	1.306PhePro: 1.306 ± 0.022	0.684PheGln: 0.684 ± 0.015	1.714PheArg: 1.714 ± 0.024	1.403PheSer: 1.403 ± 0.024	2.203PheThr: 2.203 ± 0.033	2.343PheVal: 2.343 ± 0.029	0.459PheTrp: 0.459 ± 0.014	0.656PheTyr: 0.656 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	10.581GlyAla: 10.581 ± 0.073	0.835GlyCys: 0.835 ± 0.021	5.346GlyAsp: 5.346 ± 0.051	4.433GlyGlu: 4.433 ± 0.048	2.994GlyPhe: 2.994 ± 0.032	8.597GlyGly: 8.597 ± 0.102	2.2GlyHis: 2.2 ± 0.032	3.207GlyIle: 3.207 ± 0.039	2.084GlyLys: 2.084 ± 0.035	9.55GlyLeu: 9.55 ± 0.073	1.944GlyMet: 1.944 ± 0.025	1.989GlyAsn: 1.989 ± 0.039	4.969GlyPro: 4.969 ± 0.05	2.853GlyGln: 2.853 ± 0.039	7.231GlyArg: 7.231 ± 0.061	5.061GlySer: 5.061 ± 0.052	6.02GlyThr: 6.02 ± 0.075	7.937GlyVal: 7.937 ± 0.055	1.952GlyTrp: 1.952 ± 0.03	2.449GlyTyr: 2.449 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	2.743HisAla: 2.743 ± 0.037	0.209HisCys: 0.209 ± 0.009	1.458HisAsp: 1.458 ± 0.025	1.147HisGlu: 1.147 ± 0.021	0.575HisPhe: 0.575 ± 0.015	2.322HisGly: 2.322 ± 0.032	0.713HisHis: 0.713 ± 0.019	0.601HisIle: 0.601 ± 0.015	0.265HisLys: 0.265 ± 0.012	2.505HisLeu: 2.505 ± 0.033	0.3HisMet: 0.3 ± 0.011	0.391HisAsn: 0.391 ± 0.012	1.693HisPro: 1.693 ± 0.029	0.665HisGln: 0.665 ± 0.017	2.026HisArg: 2.026 ± 0.031	0.917HisSer: 0.917 ± 0.019	1.262HisThr: 1.262 ± 0.021	1.725HisVal: 1.725 ± 0.025	0.382HisTrp: 0.382 ± 0.011	0.485HisTyr: 0.485 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	5.212IleAla: 5.212 ± 0.049	0.299IleCys: 0.299 ± 0.01	2.351IleAsp: 2.351 ± 0.031	1.903IleGlu: 1.903 ± 0.025	0.838IlePhe: 0.838 ± 0.021	3.613IleGly: 3.613 ± 0.041	0.598IleHis: 0.598 ± 0.014	1.088IleIle: 1.088 ± 0.02	0.71IleLys: 0.71 ± 0.018	2.478IleLeu: 2.478 ± 0.033	0.544IleMet: 0.544 ± 0.013	0.813IleAsn: 0.813 ± 0.02	1.693IlePro: 1.693 ± 0.027	0.722IleGln: 0.722 ± 0.018	2.201IleArg: 2.201 ± 0.028	1.842IleSer: 1.842 ± 0.027	2.49IleThr: 2.49 ± 0.037	3.103IleVal: 3.103 ± 0.034	0.462IleTrp: 0.462 ± 0.011	0.597IleTyr: 0.597 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	2.479LysAla: 2.479 ± 0.037	0.122LysCys: 0.122 ± 0.008	0.934LysAsp: 0.934 ± 0.019	0.773LysGlu: 0.773 ± 0.019	0.474LysPhe: 0.474 ± 0.015	1.389LysGly: 1.389 ± 0.026	0.383LysHis: 0.383 ± 0.011	0.864LysIle: 0.864 ± 0.019	0.559LysLys: 0.559 ± 0.027	1.954LysLeu: 1.954 ± 0.029	0.337LysMet: 0.337 ± 0.012	0.415LysAsn: 0.415 ± 0.013	1.26LysPro: 1.26 ± 0.028	0.647LysGln: 0.647 ± 0.017	1.176LysArg: 1.176 ± 0.023	0.96LysSer: 0.96 ± 0.02	1.164LysThr: 1.164 ± 0.03	1.769LysVal: 1.769 ± 0.034	0.266LysTrp: 0.266 ± 0.01	0.412LysTyr: 0.412 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	16.68LeuAla: 16.68 ± 0.104	0.812LeuCys: 0.812 ± 0.017	6.752LeuAsp: 6.752 ± 0.059	3.753LeuGlu: 3.753 ± 0.046	2.666LeuPhe: 2.666 ± 0.034	9.335LeuGly: 9.335 ± 0.073	2.3LeuHis: 2.3 ± 0.032	3.649LeuIle: 3.649 ± 0.041	1.613LeuLys: 1.613 ± 0.026	11.655LeuLeu: 11.655 ± 0.102	1.544LeuMet: 1.544 ± 0.024	1.868LeuAsn: 1.868 ± 0.027	6.662LeuPro: 6.662 ± 0.063	2.302LeuGln: 2.302 ± 0.032	8.832LeuArg: 8.832 ± 0.066	5.415LeuSer: 5.415 ± 0.045	7.072LeuThr: 7.072 ± 0.055	9.193LeuVal: 9.193 ± 0.068	1.413LeuTrp: 1.413 ± 0.022	1.869LeuTyr: 1.869 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	2.197MetAla: 2.197 ± 0.028	0.124MetCys: 0.124 ± 0.007	0.791MetAsp: 0.791 ± 0.017	0.58MetGlu: 0.58 ± 0.014	0.53MetPhe: 0.53 ± 0.015	1.182MetGly: 1.182 ± 0.023	0.349MetHis: 0.349 ± 0.011	0.805MetIle: 0.805 ± 0.017	0.362MetLys: 0.362 ± 0.013	1.89MetLeu: 1.89 ± 0.027	0.306MetMet: 0.306 ± 0.012	0.416MetAsn: 0.416 ± 0.012	1.119MetPro: 1.119 ± 0.018	0.503MetGln: 0.503 ± 0.015	1.505MetArg: 1.505 ± 0.022	1.306MetSer: 1.306 ± 0.023	1.603MetThr: 1.603 ± 0.022	1.349MetVal: 1.349 ± 0.022	0.23MetTrp: 0.23 ± 0.008	0.31MetTyr: 0.31 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.401AsnAla: 2.401 ± 0.035	0.169AsnCys: 0.169 ± 0.008	1.067AsnAsp: 1.067 ± 0.024	0.771AsnGlu: 0.771 ± 0.018	0.567AsnPhe: 0.567 ± 0.017	2.156AsnGly: 2.156 ± 0.044	0.433AsnHis: 0.433 ± 0.012	0.7AsnIle: 0.7 ± 0.016	0.377AsnLys: 0.377 ± 0.014	1.985AsnLeu: 1.985 ± 0.03	0.323AsnMet: 0.323 ± 0.01	0.577AsnAsn: 0.577 ± 0.023	1.516AsnPro: 1.516 ± 0.028	0.628AsnGln: 0.628 ± 0.016	1.363AsnArg: 1.363 ± 0.024	1.04AsnSer: 1.04 ± 0.025	1.281AsnThr: 1.281 ± 0.03	1.565AsnVal: 1.565 ± 0.026	0.365AsnTrp: 0.365 ± 0.013	0.481AsnTyr: 0.481 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	9.52ProAla: 9.52 ± 0.086	0.301ProCys: 0.301 ± 0.011	4.569ProAsp: 4.569 ± 0.048	3.393ProGlu: 3.393 ± 0.039	1.459ProPhe: 1.459 ± 0.022	6.208ProGly: 6.208 ± 0.063	1.269ProHis: 1.269 ± 0.022	1.616ProIle: 1.616 ± 0.026	1.023ProLys: 1.023 ± 0.027	5.221ProLeu: 5.221 ± 0.043	1.086ProMet: 1.086 ± 0.02	1.079ProAsn: 1.079 ± 0.021	3.767ProPro: 3.767 ± 0.066	1.922ProGln: 1.922 ± 0.029	3.574ProArg: 3.574 ± 0.043	3.403ProSer: 3.403 ± 0.049	3.564ProThr: 3.564 ± 0.04	5.558ProVal: 5.558 ± 0.051	0.987ProTrp: 0.987 ± 0.02	1.293ProTyr: 1.293 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	4.411GlnAla: 4.411 ± 0.042	0.182GlnCys: 0.182 ± 0.008	1.205GlnAsp: 1.205 ± 0.024	1.182GlnGlu: 1.182 ± 0.021	0.787GlnPhe: 0.787 ± 0.017	2.081GlnGly: 2.081 ± 0.031	0.71GlnHis: 0.71 ± 0.017	1.189GlnIle: 1.189 ± 0.023	0.453GlnLys: 0.453 ± 0.014	3.584GlnLeu: 3.584 ± 0.04	0.46GlnMet: 0.46 ± 0.014	0.514GlnAsn: 0.514 ± 0.015	1.984GlnPro: 1.984 ± 0.032	1.41GlnGln: 1.41 ± 0.032	2.764GlnArg: 2.764 ± 0.037	1.268GlnSer: 1.268 ± 0.023	1.64GlnThr: 1.64 ± 0.03	2.948GlnVal: 2.948 ± 0.03	0.581GlnTrp: 0.581 ± 0.017	0.624GlnTyr: 0.624 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	9.452ArgAla: 9.452 ± 0.072	0.558ArgCys: 0.558 ± 0.015	4.342ArgAsp: 4.342 ± 0.037	3.908ArgGlu: 3.908 ± 0.047	2.346ArgPhe: 2.346 ± 0.031	5.39ArgGly: 5.39 ± 0.052	2.154ArgHis: 2.154 ± 0.034	2.997ArgIle: 2.997 ± 0.037	1.325ArgLys: 1.325 ± 0.026	8.84ArgLeu: 8.84 ± 0.079	1.76ArgMet: 1.76 ± 0.023	1.424ArgAsn: 1.424 ± 0.023	4.713ArgPro: 4.713 ± 0.047	2.513ArgGln: 2.513 ± 0.033	7.503ArgArg: 7.503 ± 0.07	3.663ArgSer: 3.663 ± 0.048	4.597ArgThr: 4.597 ± 0.047	5.744ArgVal: 5.744 ± 0.049	1.585ArgTrp: 1.585 ± 0.022	1.848ArgTyr: 1.848 ± 0.025	0.0ArgXaa: 0.0 ± 0.0
Ser	6.883SerAla: 6.883 ± 0.053	0.392SerCys: 0.392 ± 0.011	2.436SerAsp: 2.436 ± 0.032	1.897SerGlu: 1.897 ± 0.026	1.456SerPhe: 1.456 ± 0.023	5.713SerGly: 5.713 ± 0.056	0.975SerHis: 0.975 ± 0.018	1.617SerIle: 1.617 ± 0.027	0.866SerLys: 0.866 ± 0.016	4.567SerLeu: 4.567 ± 0.041	1.073SerMet: 1.073 ± 0.021	0.925SerAsn: 0.925 ± 0.023	3.434SerPro: 3.434 ± 0.051	1.267SerGln: 1.267 ± 0.024	3.511SerArg: 3.511 ± 0.035	2.761SerSer: 2.761 ± 0.04	3.338SerThr: 3.338 ± 0.044	4.068SerVal: 4.068 ± 0.042	1.021SerTrp: 1.021 ± 0.019	1.271SerTyr: 1.271 ± 0.025	0.0SerXaa: 0.0 ± 0.0
Thr	9.462ThrAla: 9.462 ± 0.07	0.462ThrCys: 0.462 ± 0.014	3.493ThrAsp: 3.493 ± 0.039	2.822ThrGlu: 2.822 ± 0.033	1.788ThrPhe: 1.788 ± 0.03	6.81ThrGly: 6.81 ± 0.066	1.105ThrHis: 1.105 ± 0.021	2.084ThrIle: 2.084 ± 0.035	1.083ThrLys: 1.083 ± 0.026	5.963ThrLeu: 5.963 ± 0.046	1.08ThrMet: 1.08 ± 0.022	1.223ThrAsn: 1.223 ± 0.03	4.25ThrPro: 4.25 ± 0.048	1.423ThrGln: 1.423 ± 0.028	3.863ThrArg: 3.863 ± 0.041	3.219ThrSer: 3.219 ± 0.044	3.998ThrThr: 3.998 ± 0.057	6.533ThrVal: 6.533 ± 0.055	1.105ThrTrp: 1.105 ± 0.024	1.376ThrTyr: 1.376 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	12.27ValAla: 12.27 ± 0.077	0.73ValCys: 0.73 ± 0.016	5.462ValAsp: 5.462 ± 0.046	4.256ValGlu: 4.256 ± 0.048	2.44ValPhe: 2.44 ± 0.033	6.91ValGly: 6.91 ± 0.054	1.84ValHis: 1.84 ± 0.029	3.085ValIle: 3.085 ± 0.037	1.675ValLys: 1.675 ± 0.032	9.752ValLeu: 9.752 ± 0.068	1.347ValMet: 1.347 ± 0.025	1.95ValAsn: 1.95 ± 0.031	5.099ValPro: 5.099 ± 0.045	2.195ValGln: 2.195 ± 0.03	6.523ValArg: 6.523 ± 0.055	4.574ValSer: 4.574 ± 0.041	6.196ValThr: 6.196 ± 0.061	8.247ValVal: 8.247 ± 0.061	1.204ValTrp: 1.204 ± 0.025	1.782ValTyr: 1.782 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.851TrpAla: 1.851 ± 0.029	0.156TrpCys: 0.156 ± 0.009	0.828TrpAsp: 0.828 ± 0.02	0.642TrpGlu: 0.642 ± 0.016	0.548TrpPhe: 0.548 ± 0.015	1.077TrpGly: 1.077 ± 0.023	0.477TrpHis: 0.477 ± 0.013	0.602TrpIle: 0.602 ± 0.015	0.297TrpLys: 0.297 ± 0.012	2.08TrpLeu: 2.08 ± 0.027	0.286TrpMet: 0.286 ± 0.01	0.455TrpAsn: 0.455 ± 0.014	0.913TrpPro: 0.913 ± 0.021	0.757TrpGln: 0.757 ± 0.018	1.577TrpArg: 1.577 ± 0.028	1.103TrpSer: 1.103 ± 0.022	1.215TrpThr: 1.215 ± 0.023	1.094TrpVal: 1.094 ± 0.022	0.437TrpTrp: 0.437 ± 0.014	0.389TrpTyr: 0.389 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.904TyrAla: 2.904 ± 0.034	0.182TyrCys: 0.182 ± 0.008	1.492TyrAsp: 1.492 ± 0.033	1.064TyrGlu: 1.064 ± 0.021	0.678TyrPhe: 0.678 ± 0.017	2.19TyrGly: 2.19 ± 0.033	0.476TyrHis: 0.476 ± 0.012	0.48TyrIle: 0.48 ± 0.013	0.312TyrLys: 0.312 ± 0.011	2.418TyrLeu: 2.418 ± 0.033	0.216TyrMet: 0.216 ± 0.009	0.493TyrAsn: 0.493 ± 0.016	1.159TyrPro: 1.159 ± 0.021	0.744TyrGln: 0.744 ± 0.018	1.903TyrArg: 1.903 ± 0.03	0.977TyrSer: 0.977 ± 0.021	1.417TyrThr: 1.417 ± 0.03	1.697TyrVal: 1.697 ± 0.026	0.373TyrTrp: 0.373 ± 0.012	0.52TyrTyr: 0.52 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8194 proteins (2768762 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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