Amino acid dipepetide frequency for Fibroporia radiculosa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.709AlaAla: 8.709 ± 0.062	1.029AlaCys: 1.029 ± 0.017	4.488AlaAsp: 4.488 ± 0.034	5.03AlaGlu: 5.03 ± 0.043	3.295AlaPhe: 3.295 ± 0.033	5.524AlaGly: 5.524 ± 0.039	2.196AlaHis: 2.196 ± 0.024	4.261AlaIle: 4.261 ± 0.035	3.556AlaLys: 3.556 ± 0.036	8.732AlaLeu: 8.732 ± 0.051	1.98AlaMet: 1.98 ± 0.022	2.735AlaAsn: 2.735 ± 0.029	5.222AlaPro: 5.222 ± 0.046	3.539AlaGln: 3.539 ± 0.031	5.579AlaArg: 5.579 ± 0.041	8.056AlaSer: 8.056 ± 0.052	5.127AlaThr: 5.127 ± 0.04	5.653AlaVal: 5.653 ± 0.041	1.143AlaTrp: 1.143 ± 0.017	2.228AlaTyr: 2.228 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.975CysAla: 0.975 ± 0.014	0.191CysCys: 0.191 ± 0.007	0.621CysAsp: 0.621 ± 0.011	0.569CysGlu: 0.569 ± 0.012	0.468CysPhe: 0.468 ± 0.011	0.846CysGly: 0.846 ± 0.016	0.292CysHis: 0.292 ± 0.009	0.647CysIle: 0.647 ± 0.013	0.422CysLys: 0.422 ± 0.01	1.14CysLeu: 1.14 ± 0.016	0.266CysMet: 0.266 ± 0.008	0.348CysAsn: 0.348 ± 0.011	0.668CysPro: 0.668 ± 0.013	0.362CysGln: 0.362 ± 0.009	0.719CysArg: 0.719 ± 0.013	0.882CysSer: 0.882 ± 0.017	0.692CysThr: 0.692 ± 0.014	0.803CysVal: 0.803 ± 0.013	0.187CysTrp: 0.187 ± 0.005	0.327CysTyr: 0.327 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.174AspAla: 5.174 ± 0.038	0.579AspCys: 0.579 ± 0.012	4.369AspAsp: 4.369 ± 0.05	4.4AspGlu: 4.4 ± 0.041	2.046AspPhe: 2.046 ± 0.023	3.979AspGly: 3.979 ± 0.033	1.236AspHis: 1.236 ± 0.016	3.103AspIle: 3.103 ± 0.028	2.127AspLys: 2.127 ± 0.027	5.022AspLeu: 5.022 ± 0.04	1.32AspMet: 1.32 ± 0.018	1.641AspAsn: 1.641 ± 0.019	3.431AspPro: 3.431 ± 0.03	1.636AspGln: 1.636 ± 0.021	3.001AspArg: 3.001 ± 0.031	4.196AspSer: 4.196 ± 0.039	3.052AspThr: 3.052 ± 0.028	4.305AspVal: 4.305 ± 0.034	0.863AspTrp: 0.863 ± 0.015	1.453AspTyr: 1.453 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.913GluAla: 4.913 ± 0.042	0.614GluCys: 0.614 ± 0.012	4.178GluAsp: 4.178 ± 0.04	5.137GluGlu: 5.137 ± 0.055	1.876GluPhe: 1.876 ± 0.02	3.595GluGly: 3.595 ± 0.029	1.461GluHis: 1.461 ± 0.019	2.872GluIle: 2.872 ± 0.03	2.976GluLys: 2.976 ± 0.034	5.425GluLeu: 5.425 ± 0.049	1.391GluMet: 1.391 ± 0.017	1.876GluAsn: 1.876 ± 0.021	2.609GluPro: 2.609 ± 0.03	2.278GluGln: 2.278 ± 0.023	4.195GluArg: 4.195 ± 0.037	4.14GluSer: 4.14 ± 0.032	3.037GluThr: 3.037 ± 0.03	3.695GluVal: 3.695 ± 0.029	0.908GluTrp: 0.908 ± 0.016	1.579GluTyr: 1.579 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.148PheAla: 3.148 ± 0.033	0.495PheCys: 0.495 ± 0.01	2.254PheAsp: 2.254 ± 0.023	1.976PheGlu: 1.976 ± 0.019	1.499PhePhe: 1.499 ± 0.022	2.707PheGly: 2.707 ± 0.029	0.867PheHis: 0.867 ± 0.013	1.731PheIle: 1.731 ± 0.019	1.369PheLys: 1.369 ± 0.018	3.46PheLeu: 3.46 ± 0.037	0.783PheMet: 0.783 ± 0.016	1.245PheAsn: 1.245 ± 0.016	2.105PhePro: 2.105 ± 0.025	1.247PheGln: 1.247 ± 0.017	1.967PheArg: 1.967 ± 0.021	3.158PheSer: 3.158 ± 0.028	2.12PheThr: 2.12 ± 0.025	2.612PheVal: 2.612 ± 0.027	0.557PheTrp: 0.557 ± 0.012	1.045PheTyr: 1.045 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.174GlyAla: 5.174 ± 0.04	0.779GlyCys: 0.779 ± 0.016	3.469GlyAsp: 3.469 ± 0.032	3.47GlyGlu: 3.47 ± 0.033	2.494GlyPhe: 2.494 ± 0.029	5.129GlyGly: 5.129 ± 0.057	1.679GlyHis: 1.679 ± 0.022	3.203GlyIle: 3.203 ± 0.034	3.122GlyLys: 3.122 ± 0.032	5.676GlyLeu: 5.676 ± 0.038	1.548GlyMet: 1.548 ± 0.023	2.125GlyAsn: 2.125 ± 0.023	3.328GlyPro: 3.328 ± 0.033	2.32GlyGln: 2.32 ± 0.025	4.173GlyArg: 4.173 ± 0.039	5.729GlySer: 5.729 ± 0.046	3.918GlyThr: 3.918 ± 0.034	4.307GlyVal: 4.307 ± 0.033	1.095GlyTrp: 1.095 ± 0.019	1.867GlyTyr: 1.867 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.205HisAla: 2.205 ± 0.021	0.293HisCys: 0.293 ± 0.008	1.357HisAsp: 1.357 ± 0.018	1.283HisGlu: 1.283 ± 0.02	0.956HisPhe: 0.956 ± 0.015	1.623HisGly: 1.623 ± 0.021	0.78HisHis: 0.78 ± 0.017	1.33HisIle: 1.33 ± 0.018	0.858HisLys: 0.858 ± 0.015	2.487HisLeu: 2.487 ± 0.024	0.505HisMet: 0.505 ± 0.011	0.791HisAsn: 0.791 ± 0.012	1.919HisPro: 1.919 ± 0.023	0.861HisGln: 0.861 ± 0.015	1.637HisArg: 1.637 ± 0.024	2.155HisSer: 2.155 ± 0.027	1.49HisThr: 1.49 ± 0.02	1.693HisVal: 1.693 ± 0.02	0.324HisTrp: 0.324 ± 0.007	0.683HisTyr: 0.683 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.287IleAla: 4.287 ± 0.031	0.662IleCys: 0.662 ± 0.013	2.771IleAsp: 2.771 ± 0.024	2.666IleGlu: 2.666 ± 0.027	1.871IlePhe: 1.871 ± 0.025	2.999IleGly: 2.999 ± 0.034	1.183IleHis: 1.183 ± 0.018	2.339IleIle: 2.339 ± 0.028	1.899IleLys: 1.899 ± 0.024	4.606IleLeu: 4.606 ± 0.042	1.014IleMet: 1.014 ± 0.015	1.516IleAsn: 1.516 ± 0.019	3.303IlePro: 3.303 ± 0.037	1.762IleGln: 1.762 ± 0.021	2.852IleArg: 2.852 ± 0.028	4.084IleSer: 4.084 ± 0.034	2.712IleThr: 2.712 ± 0.028	3.485IleVal: 3.485 ± 0.034	0.694IleTrp: 0.694 ± 0.014	1.308IleTyr: 1.308 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	3.788LysAla: 3.788 ± 0.041	0.425LysCys: 0.425 ± 0.01	2.338LysAsp: 2.338 ± 0.028	2.863LysGlu: 2.863 ± 0.031	1.245LysPhe: 1.245 ± 0.017	2.645LysGly: 2.645 ± 0.032	1.025LysHis: 1.025 ± 0.016	1.926LysIle: 1.926 ± 0.023	2.577LysLys: 2.577 ± 0.038	3.729LysLeu: 3.729 ± 0.031	0.902LysMet: 0.902 ± 0.015	1.308LysAsn: 1.308 ± 0.019	2.333LysPro: 2.333 ± 0.03	1.546LysGln: 1.546 ± 0.021	3.272LysArg: 3.272 ± 0.032	3.06LysSer: 3.06 ± 0.029	2.353LysThr: 2.353 ± 0.023	2.59LysVal: 2.59 ± 0.03	0.614LysTrp: 0.614 ± 0.013	1.155LysTyr: 1.155 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	8.503LeuAla: 8.503 ± 0.049	1.228LeuCys: 1.228 ± 0.018	5.351LeuAsp: 5.351 ± 0.037	5.446LeuGlu: 5.446 ± 0.051	3.35LeuPhe: 3.35 ± 0.033	5.743LeuGly: 5.743 ± 0.035	2.515LeuHis: 2.515 ± 0.024	3.954LeuIle: 3.954 ± 0.037	3.776LeuLys: 3.776 ± 0.037	8.87LeuLeu: 8.87 ± 0.063	1.783LeuMet: 1.783 ± 0.022	3.061LeuAsn: 3.061 ± 0.026	6.33LeuPro: 6.33 ± 0.043	3.824LeuGln: 3.824 ± 0.034	6.259LeuArg: 6.259 ± 0.046	8.414LeuSer: 8.414 ± 0.051	5.299LeuThr: 5.299 ± 0.039	6.01LeuVal: 6.01 ± 0.047	1.196LeuTrp: 1.196 ± 0.017	2.402LeuTyr: 2.402 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	1.922MetAla: 1.922 ± 0.021	0.248MetCys: 0.248 ± 0.007	1.235MetAsp: 1.235 ± 0.017	1.199MetGlu: 1.199 ± 0.015	0.782MetPhe: 0.782 ± 0.014	1.361MetGly: 1.361 ± 0.021	0.561MetHis: 0.561 ± 0.012	0.929MetIle: 0.929 ± 0.014	0.887MetLys: 0.887 ± 0.013	1.946MetLeu: 1.946 ± 0.022	0.516MetMet: 0.516 ± 0.013	0.765MetAsn: 0.765 ± 0.014	1.357MetPro: 1.357 ± 0.019	0.881MetGln: 0.881 ± 0.014	1.4MetArg: 1.4 ± 0.018	2.191MetSer: 2.191 ± 0.023	1.241MetThr: 1.241 ± 0.017	1.233MetVal: 1.233 ± 0.017	0.274MetTrp: 0.274 ± 0.008	0.539MetTyr: 0.539 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.092AsnAla: 3.092 ± 0.029	0.334AsnCys: 0.334 ± 0.01	1.709AsnAsp: 1.709 ± 0.021	1.706AsnGlu: 1.706 ± 0.022	1.177AsnPhe: 1.177 ± 0.018	2.484AsnGly: 2.484 ± 0.029	0.723AsnHis: 0.723 ± 0.014	1.831AsnIle: 1.831 ± 0.021	1.203AsnLys: 1.203 ± 0.02	3.004AsnLeu: 3.004 ± 0.03	0.77AsnMet: 0.77 ± 0.014	1.137AsnAsn: 1.137 ± 0.018	2.187AsnPro: 2.187 ± 0.022	0.99AsnGln: 0.99 ± 0.015	1.621AsnArg: 1.621 ± 0.02	2.501AsnSer: 2.501 ± 0.026	1.951AsnThr: 1.951 ± 0.023	2.457AsnVal: 2.457 ± 0.025	0.455AsnTrp: 0.455 ± 0.011	0.893AsnTyr: 0.893 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.645ProAla: 5.645 ± 0.051	0.467ProCys: 0.467 ± 0.011	3.337ProAsp: 3.337 ± 0.03	3.583ProGlu: 3.583 ± 0.03	2.202ProPhe: 2.202 ± 0.025	3.833ProGly: 3.833 ± 0.035	1.662ProHis: 1.662 ± 0.021	2.822ProIle: 2.822 ± 0.028	2.222ProLys: 2.222 ± 0.026	5.66ProLeu: 5.66 ± 0.04	1.135ProMet: 1.135 ± 0.015	2.043ProAsn: 2.043 ± 0.021	6.487ProPro: 6.487 ± 0.083	2.417ProGln: 2.417 ± 0.032	3.737ProArg: 3.737 ± 0.035	7.483ProSer: 7.483 ± 0.073	4.384ProThr: 4.384 ± 0.04	4.047ProVal: 4.047 ± 0.034	0.667ProTrp: 0.667 ± 0.012	1.646ProTyr: 1.646 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.36GlnAla: 3.36 ± 0.035	0.432GlnCys: 0.432 ± 0.012	1.993GlnAsp: 1.993 ± 0.021	2.215GlnGlu: 2.215 ± 0.024	1.259GlnPhe: 1.259 ± 0.016	2.084GlnGly: 2.084 ± 0.022	1.022GlnHis: 1.022 ± 0.016	1.74GlnIle: 1.74 ± 0.022	1.532GlnLys: 1.532 ± 0.022	3.518GlnLeu: 3.518 ± 0.03	0.81GlnMet: 0.81 ± 0.013	1.274GlnAsn: 1.274 ± 0.018	2.387GlnPro: 2.387 ± 0.03	1.823GlnGln: 1.823 ± 0.036	2.514GlnArg: 2.514 ± 0.025	3.111GlnSer: 3.111 ± 0.032	2.237GlnThr: 2.237 ± 0.025	2.213GlnVal: 2.213 ± 0.022	0.549GlnTrp: 0.549 ± 0.012	1.12GlnTyr: 1.12 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.446ArgAla: 5.446 ± 0.041	0.699ArgCys: 0.699 ± 0.013	3.416ArgAsp: 3.416 ± 0.031	3.97ArgGlu: 3.97 ± 0.038	2.15ArgPhe: 2.15 ± 0.027	3.685ArgGly: 3.685 ± 0.036	1.637ArgHis: 1.637 ± 0.021	3.063ArgIle: 3.063 ± 0.024	3.296ArgLys: 3.296 ± 0.033	5.918ArgLeu: 5.918 ± 0.045	1.439ArgMet: 1.439 ± 0.019	1.985ArgAsn: 1.985 ± 0.022	3.865ArgPro: 3.865 ± 0.045	2.457ArgGln: 2.457 ± 0.027	5.493ArgArg: 5.493 ± 0.048	5.381ArgSer: 5.381 ± 0.051	3.699ArgThr: 3.699 ± 0.034	3.808ArgVal: 3.808 ± 0.032	0.925ArgTrp: 0.925 ± 0.015	1.591ArgTyr: 1.591 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.656SerAla: 7.656 ± 0.053	0.872SerCys: 0.872 ± 0.015	4.592SerAsp: 4.592 ± 0.036	4.234SerGlu: 4.234 ± 0.032	3.099SerPhe: 3.099 ± 0.03	5.75SerGly: 5.75 ± 0.045	2.177SerHis: 2.177 ± 0.026	4.05SerIle: 4.05 ± 0.032	3.266SerLys: 3.266 ± 0.033	8.106SerLeu: 8.106 ± 0.05	1.863SerMet: 1.863 ± 0.023	2.739SerAsn: 2.739 ± 0.023	6.862SerPro: 6.862 ± 0.07	3.215SerGln: 3.215 ± 0.035	5.541SerArg: 5.541 ± 0.051	10.465SerSer: 10.465 ± 0.097	6.149SerThr: 6.149 ± 0.055	5.509SerVal: 5.509 ± 0.038	1.089SerTrp: 1.089 ± 0.017	2.135SerTyr: 2.135 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.088ThrAla: 5.088 ± 0.034	0.675ThrCys: 0.675 ± 0.014	2.828ThrAsp: 2.828 ± 0.026	2.839ThrGlu: 2.839 ± 0.027	2.372ThrPhe: 2.372 ± 0.024	3.808ThrGly: 3.808 ± 0.037	1.477ThrHis: 1.477 ± 0.021	3.066ThrIle: 3.066 ± 0.03	2.167ThrLys: 2.167 ± 0.028	5.797ThrLeu: 5.797 ± 0.045	1.176ThrMet: 1.176 ± 0.016	1.884ThrAsn: 1.884 ± 0.023	4.63ThrPro: 4.63 ± 0.052	2.041ThrGln: 2.041 ± 0.025	3.485ThrArg: 3.485 ± 0.032	5.836ThrSer: 5.836 ± 0.051	4.079ThrThr: 4.079 ± 0.043	3.903ThrVal: 3.903 ± 0.034	0.776ThrTrp: 0.776 ± 0.015	1.616ThrTyr: 1.616 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.548ValAla: 5.548 ± 0.038	0.861ValCys: 0.861 ± 0.014	4.052ValAsp: 4.052 ± 0.028	3.908ValGlu: 3.908 ± 0.029	2.555ValPhe: 2.555 ± 0.03	4.074ValGly: 4.074 ± 0.036	1.685ValHis: 1.685 ± 0.018	3.079ValIle: 3.079 ± 0.031	2.696ValLys: 2.696 ± 0.029	6.413ValLeu: 6.413 ± 0.044	1.332ValMet: 1.332 ± 0.018	2.181ValAsn: 2.181 ± 0.026	4.257ValPro: 4.257 ± 0.029	2.573ValGln: 2.573 ± 0.027	3.994ValArg: 3.994 ± 0.036	5.393ValSer: 5.393 ± 0.039	3.578ValThr: 3.578 ± 0.032	4.833ValVal: 4.833 ± 0.043	0.969ValTrp: 0.969 ± 0.017	1.82ValTyr: 1.82 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.119TrpAla: 1.119 ± 0.017	0.185TrpCys: 0.185 ± 0.007	0.906TrpAsp: 0.906 ± 0.017	0.83TrpGlu: 0.83 ± 0.016	0.54TrpPhe: 0.54 ± 0.012	0.846TrpGly: 0.846 ± 0.016	0.342TrpHis: 0.342 ± 0.009	0.712TrpIle: 0.712 ± 0.012	0.732TrpLys: 0.732 ± 0.014	1.297TrpLeu: 1.297 ± 0.022	0.355TrpMet: 0.355 ± 0.009	0.583TrpAsn: 0.583 ± 0.012	0.602TrpPro: 0.602 ± 0.013	0.5TrpGln: 0.5 ± 0.012	0.975TrpArg: 0.975 ± 0.017	1.072TrpSer: 1.072 ± 0.015	0.852TrpThr: 0.852 ± 0.015	0.848TrpVal: 0.848 ± 0.014	0.278TrpTrp: 0.278 ± 0.009	0.382TrpTyr: 0.382 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.329TyrAla: 2.329 ± 0.026	0.357TyrCys: 0.357 ± 0.01	1.668TyrAsp: 1.668 ± 0.02	1.43TyrGlu: 1.43 ± 0.02	1.111TyrPhe: 1.111 ± 0.018	1.891TyrGly: 1.891 ± 0.027	0.709TyrHis: 0.709 ± 0.012	1.355TyrIle: 1.355 ± 0.018	1.01TyrLys: 1.01 ± 0.015	2.508TyrLeu: 2.508 ± 0.023	0.582TyrMet: 0.582 ± 0.012	0.989TyrAsn: 0.989 ± 0.016	1.593TyrPro: 1.593 ± 0.023	0.919TyrGln: 0.919 ± 0.014	1.511TyrArg: 1.511 ± 0.019	2.063TyrSer: 2.063 ± 0.021	1.571TyrThr: 1.571 ± 0.02	1.798TyrVal: 1.798 ± 0.021	0.395TyrTrp: 0.395 ± 0.008	0.861TyrTyr: 0.861 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9251 proteins (4412171 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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